Mercurial > repos > davidvanzessen > shm_csr
diff tests/data/1_Summary.txt @ 99:5b79485234e1 draft default tip
planemo upload commit 0d652311f9c4ccc26b27eebc44a3ae91a72e57b0
| author | rhpvorderman |
|---|---|
| date | Mon, 03 Feb 2025 13:37:26 +0000 |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/tests/data/1_Summary.txt Mon Feb 03 13:37:26 2025 +0000 @@ -0,0 +1,22434 @@ +Sequence number Sequence ID Functionality V-GENE and allele V-REGION score V-REGION identity % V-REGION identity nt V-REGION identity % (with ins/del events) V-REGION identity nt (with ins/del events) J-GENE and allele J-REGION score J-REGION identity % J-REGION identity nt D-GENE and allele D-REGION reading frame CDR1-IMGT length CDR2-IMGT length CDR3-IMGT length CDR-IMGT lengths FR-IMGT lengths AA JUNCTION JUNCTION frame Orientation Functionality comment V-REGION potential ins/del J-GENE and allele comment V-REGION insertions V-REGION deletions Sequence +1 JY8QFUQ01DD1I8 No results +2 JY8QFUQ01BR14W unknown (see comment) Homsap IGHV3-16*01 ORF, or Homsap IGHV3-16*02 ORF or Homsap IGHV3-19*01 P or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-35*01 ORF or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 134 88.24 30/34 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found tctggattcaccttcagcaaccataacatgaact +3 JY8QFUQ01DI33C No results +4 JY8QFUQ01AHA5U No results +5 JY8QFUQ01C6E2Q No results +6 JY8QFUQ01DTOF7 No results +7 JY8QFUQ01DTQZ4 No results +8 JY8QFUQ01CH7HW No results +9 JY8QFUQ01DRIUN No results +10 JY8QFUQ01DMFB3 No results +11 JY8QFUQ01DBKZ5 No results +12 JY8QFUQ01ALILW No results +13 JY8QFUQ01DQT5M No results +14 JY8QFUQ01CU1U5 No results +15 JY8QFUQ01AZ7M4 No results +16 JY8QFUQ01BJI4T No results +17 JY8QFUQ01A8WKP No results +18 JY8QFUQ01CDRAH No results +19 JY8QFUQ01BSZTH No results +20 JY8QFUQ01COV1I No results +21 JY8QFUQ01BYN3R No results +22 JY8QFUQ01BB6L9 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 121 69.81 37/53 nt 8 X X 8.X.X [1.8.X.X] null + No rearrangement found tccggattcacctttagtagttactggatgcactgggtccagggcttcttccc +23 JY8QFUQ01AK5S0 No results +24 JY8QFUQ01A3U3N No results +25 JY8QFUQ01DMJ3V No results +26 JY8QFUQ01DULTP No results +27 JY8QFUQ01DXFUU No results +28 JY8QFUQ01BDHX9 No results +29 JY8QFUQ01BFXXE No results +30 JY8QFUQ01DA0S9 No results +31 JY8QFUQ01A8RD7 No results +32 JY8QFUQ01DUD3G unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 167 94.59 35/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcacctttggttattatggcatgagctgg +33 JY8QFUQ01BAEVW unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 412 81.97 100/122 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found Low V-REGION identity (81,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgtttctacttacaccattttctacgcagagtctgtta +34 JY8QFUQ01C5VTQ No results +35 JY8QFUQ01DV0LO unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 442 93.07 94/101 nt 8 7 X 8.7.X [1.17.X.X] null + No rearrangement found ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgaca +36 JY8QFUQ01BQV49 No results +37 JY8QFUQ01BG2BI No results +38 JY8QFUQ01DDCUU unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 709 79.73 177/222 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 10 X 8.10.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (79,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcactgtcaataacgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgatggcgggacagcagactacgctccatttgtggacgacagattcaccatttcaacagatgattcaaaaatcacgttgtatctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +39 JY8QFUQ01DTYS9 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 122 69.09 38/55 nt 8 X X 8.X.X [1.9.X.X] null + No rearrangement found tctggattcacctttagtaaccattggatgaactgggtccagggcttcttcccca +40 JY8QFUQ01DWUUL No results +41 JY8QFUQ01BDC06 No results +42 JY8QFUQ01DQ6VG unknown (see comment) Homsap IGHV1-NL1*01 P 84 56.41 44/78 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccaga +43 JY8QFUQ01C3GCP No results +44 JY8QFUQ01A1UV9 No results +45 JY8QFUQ01CVLJY No results +46 JY8QFUQ01BAK18 No results +47 JY8QFUQ01CEPBG No results +48 JY8QFUQ01ART19 No results +49 JY8QFUQ01CA0L6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 95 57.32 47/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttcccgcaccagtcgacggtgtcgtggaactcag +50 JY8QFUQ01BLYKI No results +51 JY8QFUQ01CMHH0 No results +52 JY8QFUQ01DTU6H No results +53 JY8QFUQ01AFK93 No results +54 JY8QFUQ01CAQ1G No results +55 JY8QFUQ01DGVKY No results +56 JY8QFUQ01DTVWR No results +57 JY8QFUQ01DHF6P No results +58 JY8QFUQ01DW0GO unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +59 JY8QFUQ01B3H3U No results +60 JY8QFUQ01BG2D6 No results +61 JY8QFUQ01CU2N8 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 506 82.43 122/148 nt 8 8 X 8.8.X [4.17.12.X] null + No rearrangement found Low V-REGION identity (82,43% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgcagcctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactca +62 JY8QFUQ01DPEOQ No results +63 JY8QFUQ01DVW6F No results +64 JY8QFUQ01BZICQ No results +65 JY8QFUQ01DTLA9 No results +66 JY8QFUQ01DI96Y unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 206 97.67 42/43 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found tctggattcaccttcagtagctactggatgcactgggtccccc +67 JY8QFUQ01ASP3F No results +68 JY8QFUQ01DU9Q8 No results +69 JY8QFUQ01CUFKA No results +70 JY8QFUQ01DE7XG No results +71 JY8QFUQ01DDYY7 No results +72 JY8QFUQ01CKJ4D No results +73 JY8QFUQ01CE6UI No results +74 JY8QFUQ01B2WAW No results +75 JY8QFUQ01BZYKW No results +76 JY8QFUQ01DV6KB No results +77 JY8QFUQ01CVA7X unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcatcttcagtagctactggatgcactggg +78 JY8QFUQ01BWC41 No results +79 JY8QFUQ01DPMI5 No results +80 JY8QFUQ01BZF17 No results +81 JY8QFUQ01C8FAJ No results +82 JY8QFUQ01DM452 No results +83 JY8QFUQ01BJZEA No results +84 JY8QFUQ01BKHV9 unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F (see comment) 627 80.73 155/192 nt 80.21 154/192 nt 7 7 X 7.7.X [1.17.31.X] null + No rearrangement found Low V-REGION identity (80,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) tctggattcaccgtcaatagaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaaggactacttccccgaaccggtgacggtgtcgtggaactcag +85 JY8QFUQ01C942O No results +86 JY8QFUQ01CSVTG unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +87 JY8QFUQ01DVNMI No results +88 JY8QFUQ01CTXI4 No results +89 JY8QFUQ01BLB8J No results +90 JY8QFUQ01DLI1K No results +91 JY8QFUQ01CDDFH No results +92 JY8QFUQ01ANSE9 No results +93 JY8QFUQ01DTA69 No results +94 JY8QFUQ01CGH3T No results +95 JY8QFUQ01C79ZO No results +96 JY8QFUQ01BW552 No results +97 JY8QFUQ01A71P8 No results +98 JY8QFUQ01DM7US No results +99 JY8QFUQ01AUTO1 No results +100 JY8QFUQ01DFULG No results +101 JY8QFUQ01DU8HP No results +102 JY8QFUQ01CSLDE No results +103 JY8QFUQ01DJDQI unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 494 96.23 102/106 nt 8 8 X 8.8.X [1.17.1.X] null + No rearrangement found tctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatact +104 JY8QFUQ01CHLO2 No results +105 JY8QFUQ01C0YZ5 No results +106 JY8QFUQ01BFBEW unknown (see comment) Homsap IGHV7-81*01 ORF 119 77.5 31/40 nt 8 X X 8.X.X [1.4.X.X] null + No rearrangement found tctggattcagcctcgccacttatagtatgagttgggtcc +107 JY8QFUQ01DGR36 No results +108 JY8QFUQ01BZAA8 No results +109 JY8QFUQ01AK0R1 unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F (see comment) 612 75.58 164/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +110 JY8QFUQ01ALF4T unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggtagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +111 JY8QFUQ01CTJBP unknown (see comment) Homsap IGHV3-7*02 F 108 59.26 48/81 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +112 JY8QFUQ01BAW8J No results +113 JY8QFUQ01DSN7R No results +114 JY8QFUQ01CIMDF No results +115 JY8QFUQ01AEIQD No results +116 JY8QFUQ01ALOXD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +117 JY8QFUQ01AQN2C No results +118 JY8QFUQ01BGKOV No results +119 JY8QFUQ01DDRSG No results +120 JY8QFUQ01AHLWO unknown (see comment) Homsap IGHV3-7*01 F (see comment) 747 82.49 179/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggagtcacctttagtgactattggatgagctggatccgccaggctccagggaaggggccggagtgggtggccaacatagagcaagatgggagtgagataaattatgtggactctgtgaagggccgattcaccatctccagagacaacaccgagaatgcactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttcccctggcgcctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +121 JY8QFUQ01AN0SO unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 193 93.18 41/44 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found tctggattcaccttcagcaagtatgccatgagctgggtccgcca +122 JY8QFUQ01CT52V No results +123 JY8QFUQ01CWLUO No results +124 JY8QFUQ01A2ELS No results +125 JY8QFUQ01DOEGW No results +126 JY8QFUQ01CSUXL No results +127 JY8QFUQ01CT2OK No results +128 JY8QFUQ01DOFCV No results +129 JY8QFUQ01DGWX7 No results +130 JY8QFUQ01CGOFR unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-30*02 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*05 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*12 F or Homsap IGHV3-30*13 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 126 83.33 30/36 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found tctggattcagcctcacttcctatggcatgaactgg +131 JY8QFUQ01CNLGG No results +132 JY8QFUQ01AYFAD No results +133 JY8QFUQ01BVDR4 No results +134 JY8QFUQ01DOXX1 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 168 58.91 76/129 nt 8 6 X 8.6.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +135 JY8QFUQ01BDB4H No results +136 JY8QFUQ01DIGN2 unknown (see comment) Homsap IGHV7-81*01 ORF 98 76.47 26/34 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found tctggattcagcctcgccacttatagtatgagtt +137 JY8QFUQ01BIZ21 No results +138 JY8QFUQ01DB13R No results +139 JY8QFUQ01DAU01 No results +140 JY8QFUQ01BR5FT No results +141 JY8QFUQ01A37Q6 No results +142 JY8QFUQ01DUO5E No results +143 JY8QFUQ01C5YGF No results +144 JY8QFUQ01AO7LQ No results +145 JY8QFUQ01A3ZCN No results +146 JY8QFUQ01DP11J No results +147 JY8QFUQ01BJSFE No results +148 JY8QFUQ01CVDV0 No results +149 JY8QFUQ01COZ0J unknown (see comment) Homsap IGHV3-66*02 F 724 91.76 156/170 nt 90.59 154/170 nt 8 6 X 8.6.X [4.16.21.X] null - No rearrangement found in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 63 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 89 in the user submitted sequence), (cause frameshift) tctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccaggaagggctggactgcgtctcagttattatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgta +150 JY8QFUQ01BS64J No results +151 JY8QFUQ01CQ9CW No results +152 JY8QFUQ01DCLVR unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 87 51.94 67/129 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons tctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +153 JY8QFUQ01A1QTO No results +154 JY8QFUQ01A83B7 No results +155 JY8QFUQ01DWC5U No results +156 JY8QFUQ01BGBH9 No results +157 JY8QFUQ01DB7E1 No results +158 JY8QFUQ01DVKJB No results +159 JY8QFUQ01DG72B No results +160 JY8QFUQ01AY84U No results +161 JY8QFUQ01AEJBJ No results +162 JY8QFUQ01DB5ED No results +163 JY8QFUQ01C3EIC unknown (see comment) Homsap IGHV1-58*01 F, or Homsap IGHV1-58*02 F or Homsap IGHV3-11*01 F or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F 45 100.0 9/9 nt 2 X X 2.X.X [0.X.X.X] null + No rearrangement found ctggattca +164 JY8QFUQ01CAHKQ No results +165 JY8QFUQ01A1A0E No results +166 JY8QFUQ01BYHJD No results +167 JY8QFUQ01DOTCX No results +168 JY8QFUQ01CAYCB No results +169 JY8QFUQ01B5FJJ No results +170 JY8QFUQ01AH7DD No results +171 JY8QFUQ01BR117 No results +172 JY8QFUQ01BB0TH unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 462 70.77 138/195 nt 8 7 X 8.7.X [1.17.32.X] null + No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BB0TH ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (70,77% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +173 JY8QFUQ01CXC3R unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 348 86.02 80/93 nt 8 5 X 8.5.X [1.17.X.X] null + No rearrangement found tctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc +174 JY8QFUQ01BY61P No results +175 JY8QFUQ01A2HZI No results +176 JY8QFUQ01DAXAJ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 479 82.73 115/139 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (82,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc +177 JY8QFUQ01DLHM1 No results +178 JY8QFUQ01CH35Q No results +179 JY8QFUQ01A6JB1 No results +180 JY8QFUQ01A3M0Z unproductive (see comment) Homsap IGHV3-48*02 F 119 58.95 56/95 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 X X X X.X.X [X.X.31.11] CAGQWQGS#YGINVW out-of-frame + stop codons Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcaattcctataccatgatgtgggtcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcggggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +181 JY8QFUQ01BVB4O No results +182 JY8QFUQ01BYT51 No results +183 JY8QFUQ01DRQ90 No results +184 JY8QFUQ01CTBQK No results +185 JY8QFUQ01A8U9M unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 262 61.27 106/173 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found Low V-REGION identity (61,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccagg +186 JY8QFUQ01A13K0 No results +187 JY8QFUQ01B0KSX unknown (see comment) Homsap IGHV3-64*02 F, or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 138 56.06 74/132 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons tctggattcaccttcagtgactatgccatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +188 JY8QFUQ01A0UIS No results +189 JY8QFUQ01CTF2E No results +190 JY8QFUQ01C986B No results +191 JY8QFUQ01A52NX No results +192 JY8QFUQ01CP60A No results +193 JY8QFUQ01A0IDA No results +194 JY8QFUQ01BYV10 No results +195 JY8QFUQ01A1Z98 No results +196 JY8QFUQ01DWS1H unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F (see comment) 449 72.47 129/178 nt 71.91 128/178 nt 8 8 X 8.8.X [1.16.25.X] null + No rearrangement found Low V-REGION identity (72,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaagggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +197 JY8QFUQ01B39DQ No results +198 JY8QFUQ01BMPRJ No results +199 JY8QFUQ01CSA7J unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 86 94.74 18/19 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found tctggattcacctttaaca +200 JY8QFUQ01ALH3Y No results +201 JY8QFUQ01B0IJE No results +202 JY8QFUQ01CCW9C No results +203 JY8QFUQ01CTHJF No results +204 JY8QFUQ01CJ0PY No results +205 JY8QFUQ01CQDYQ No results +206 JY8QFUQ01BVQA9 No results +207 JY8QFUQ01CNN0N No results +208 JY8QFUQ01CTW86 No results +209 JY8QFUQ01CY6WQ productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [2.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); agtctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +210 JY8QFUQ01CFDPF No results +211 JY8QFUQ01CZBUH No results +212 JY8QFUQ01DH7FZ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-23*01 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 329 62.81 125/199 nt 8 8 X 8.8.X [1.17.32.X] null + No rearrangement found Low V-REGION identity (62,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcgacttcagtagatatatcatgaattgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +213 JY8QFUQ01CQK1N No results +214 JY8QFUQ01BLRBA No results +215 JY8QFUQ01C9N72 No results +216 JY8QFUQ01CWO5P No results +217 JY8QFUQ01A9JCI No results +218 JY8QFUQ01DE0PS No results +219 JY8QFUQ01DR84G unknown (see comment) Homsap IGHV3-7*02 F 99 58.02 47/81 nt 8 1 X 8.1.X [0.17.X.X] null + No rearrangement found ctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +220 JY8QFUQ01BARRD No results +221 JY8QFUQ01C1NR2 No results +222 JY8QFUQ01AHAFH No results +223 JY8QFUQ01A26OK No results +224 JY8QFUQ01CGWCE No results +225 JY8QFUQ01DVLDK No results +226 JY8QFUQ01CJXM7 No results +227 JY8QFUQ01DS8UG No results +228 JY8QFUQ01A5YUQ No results +229 JY8QFUQ01AYPSG No results +230 JY8QFUQ01DHCTP No results +231 JY8QFUQ01C2R6X No results +232 JY8QFUQ01DCWWX unknown (see comment) Homsap IGHV3-NL1*01 F (see comment) 237 65.85 81/123 nt 8 7 X 8.7.X [1.17.8.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DCWWX ; 8 AA in Homsap_IGHV3-NL1*01), and low V-REGION identity (65,85% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggatcccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +233 JY8QFUQ01BBIRD No results +234 JY8QFUQ01BUPUP unknown (see comment) Homsap IGHV3-52*01 P, or Homsap IGHV3-52*02 P or Homsap IGHV3-52*03 P or Homsap IGHV3-74*01 F or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 115 84.38 27/32 nt 8 X X 8.X.X [1.1.X.X] null + No rearrangement found gtctggatttaccttcagtaagttctggatgc +235 JY8QFUQ01A14E7 No results +236 JY8QFUQ01BPOEB No results +237 JY8QFUQ01BIXXS No results +238 JY8QFUQ01DEYOG No results +239 JY8QFUQ01DT1EA No results +240 JY8QFUQ01DDCTT No results +241 JY8QFUQ01C8365 No results +242 JY8QFUQ01AFEYM No results +243 JY8QFUQ01BLXFI No results +244 JY8QFUQ01CVJ8R No results +245 JY8QFUQ01DEM1N productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 692 80.47 173/215 nt 80.0 172/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 78 of V-REGION: 'AG' (2 nucleotides at position 136 to 137 in the user submitted sequence), (cause frameshift); tctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcgaAGtctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +246 JY8QFUQ01BJ01G No results +247 JY8QFUQ01C1OWK No results +248 JY8QFUQ01A4123 No results +249 JY8QFUQ01DBK0C No results +250 JY8QFUQ01AG8OC No results +251 JY8QFUQ01DK7J9 No results +252 JY8QFUQ01CZKX8 No results +253 JY8QFUQ01BSZE3 No results +254 JY8QFUQ01DMJ2K No results +255 JY8QFUQ01AYEJ5 unknown (see comment) Homsap IGHV4-61*02 F (see comment) 262 83.78 62/74 nt 10 X X 10.X.X [1.13.X.X] null + No rearrangement found Low V-REGION identity (83,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgcctggatccggcagccc +256 JY8QFUQ01DCN17 No results +257 JY8QFUQ01AB5K5 No results +258 JY8QFUQ01DVMBC No results +259 JY8QFUQ01DSA05 No results +260 JY8QFUQ01CTTZZ No results +261 JY8QFUQ01C428X No results +262 JY8QFUQ01CBV3X No results +263 JY8QFUQ01DHY8X unproductive Homsap IGHV3-15*04 F 979 93.69 208/222 nt 92.79 206/222 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-15*01 F 3 8 9 X 8.9.X [1.17.38.11] CAADGCPGGTCYHG#LDMW out-of-frame + in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtaacgtctggatgcactgggtccgccaggctccagggaaggggctggagtggttgggccgtattgaGaagcaaaactgctggtgggcaacagaatacgctgcgcccgtgagaggcatattctccatctcaagagatgattcaaagaacacgttgtatctgcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtgccgcagatggttgtcctggtggtacctgctatcatggttttggatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagcccctaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcncatgcctggtccagggcttcttcccc +264 JY8QFUQ01AV5JR unproductive (see comment) Homsap IGHV4-61*02 F (see comment) 757 83.11 182/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null + stop codons no junction found Low V-REGION identity (83,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggtggccccatcaacagtgatggtcaatattggaactggatccggcagcccgccgggaagggactggagtggatcggacatgtttacagtggtgggggtaccaattataattcgtccttcgggagtcgagtcaccatgtcattagacatgtccaacaaccagttctccctgatattgagctctgtgacggccgcagacacggccatatattactgtgcgagagaacgtggtagggcgactgccggagcgagagaccttgactcctggggccagggaatcctgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccaggatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +265 JY8QFUQ01DI7LG unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 353 86.17 81/94 nt 8 5 X 8.5.X [1.17.X.X] null + No rearrangement found ctctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc +266 JY8QFUQ01B15JZ No results +267 JY8QFUQ01AL59V No results +268 JY8QFUQ01BL0MP No results +269 JY8QFUQ01DFOIH No results +270 JY8QFUQ01C121A unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 91 52.34 67/128 nt 8 8 X 8.8.X [1.17.8.X] null + No rearrangement found stop codons tctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +271 JY8QFUQ01A6J9J No results +272 JY8QFUQ01BQ44V No results +273 JY8QFUQ01BV9HI No results +274 JY8QFUQ01DEZCV No results +275 JY8QFUQ01DXIEO No results +276 JY8QFUQ01BBTMB unknown (see comment) Homsap IGHV3-13*02 F 106 54.1 66/122 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found tctggattctccttcagggaccactatattgactgggtccgccaagctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaact +277 JY8QFUQ01DQ1GX No results +278 JY8QFUQ01ACHTP unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 364 82.24 88/107 nt 8 8 X 8.8.X [1.17.1.X] null + No rearrangement found Low V-REGION identity (82,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcggaattctccgtcagtgacagtcacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagccattagtggcagtggtagtcggacatatt +279 JY8QFUQ01C65ZI No results +280 JY8QFUQ01CV0X9 No results +281 JY8QFUQ01AQI9Z unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 110 53.24 74/139 nt 10 7 X 10.7.X [1.17.10.X] null + No rearrangement found stop codons tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +282 JY8QFUQ01C47CW No results +283 JY8QFUQ01AR7AS No results +284 JY8QFUQ01C1HDQ No results +285 JY8QFUQ01C6OZG No results +286 JY8QFUQ01A7RVP No results +287 JY8QFUQ01DLTX0 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 211 97.73 43/44 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found tctggattcaccttcagtagctactggatgcactgggtccccca +288 JY8QFUQ01BXUAZ No results +289 JY8QFUQ01AWANM No results +290 JY8QFUQ01BAYFL unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 949 93.06 201/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaact +291 JY8QFUQ01AB9J6 No results +292 JY8QFUQ01B3J0Z No results +293 JY8QFUQ01B452T No results +294 JY8QFUQ01AM7B2 No results +295 JY8QFUQ01BOC5Y No results +296 JY8QFUQ01DCO0T No results +297 JY8QFUQ01ARPT9 No results +298 JY8QFUQ01BTB20 No results +299 JY8QFUQ01A65TQ No results +300 JY8QFUQ01CF5J0 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-7*02 F 117 60.49 49/81 nt 8 X X 8.X.X [1.17.X.X] null - No rearrangement found cctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +301 JY8QFUQ01BOL3F No results +302 JY8QFUQ01CZJHH No results +303 JY8QFUQ01A885O No results +304 JY8QFUQ01BJQ8R unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 466 71.13 138/194 nt 70.62 137/194 nt 8 7 X 8.7.X [1.17.31.X] null + No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BJQ8R ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (71,13% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 118 in the user submitted sequence), (cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgagggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +305 JY8QFUQ01DM3J7 No results +306 JY8QFUQ01BQJMM No results +307 JY8QFUQ01AUM5I No results +308 JY8QFUQ01DQNQS No results +309 JY8QFUQ01CIIWH No results +310 JY8QFUQ01C4XTE No results +311 JY8QFUQ01DTPYG No results +312 JY8QFUQ01AP5CO No results +313 JY8QFUQ01AI1VB unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 110 53.24 74/139 nt 10 7 X 10.7.X [1.17.10.X] null + No rearrangement found stop codons tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +314 JY8QFUQ01ASZ6N No results +315 JY8QFUQ01BN97P unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F or Homsap IGHV1-18*04 F or Homsap IGHV1-2*01 F or Homsap IGHV1-2*02 F or Homsap IGHV1-2*04 F or Homsap IGHV1-2*05 F or Homsap IGHV1-24*01 F or Homsap IGHV1-3*01 F or Homsap IGHV1-3*02 F or Homsap IGHV1-46*01 F or Homsap IGHV1-46*02 F 61 92.86 13/14 nt X X X X.X.X [4.X.X.X] null + No rearrangement found gggaagaagcctgg +316 JY8QFUQ01C1J78 No results +317 JY8QFUQ01BW4EH No results +318 JY8QFUQ01C3NX6 No results +319 JY8QFUQ01DKFWF No results +320 JY8QFUQ01AE4WV No results +321 JY8QFUQ01C2JYZ No results +322 JY8QFUQ01C7IX0 No results +323 JY8QFUQ01DOGI5 No results +324 JY8QFUQ01B9NL7 No results +325 JY8QFUQ01DM71E unknown (see comment) Homsap IGHV3-72*01 F 110 53.85 70/130 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +326 JY8QFUQ01BJTSM No results +327 JY8QFUQ01DQW5Y No results +328 JY8QFUQ01DK75G No results +329 JY8QFUQ01BM2U2 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +330 JY8QFUQ01B3A93 unknown (see comment) Homsap IGHV1-2*02 F 491 87.4 111/127 nt 86.61 110/127 nt 7 8 X 7.8.X [0.17.9.X] null + No rearrangement found in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift) tggatacatttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcaggg +331 JY8QFUQ01B07TW unknown (see comment) Homsap IGHV1-58*01 F, or Homsap IGHV1-58*02 F or Homsap IGHV3-11*01 F or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F 50 100.0 10/10 nt 2 X X 2.X.X [1.X.X.X] null + No rearrangement found tctggattca +332 JY8QFUQ01A6ZXF unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 137 56.15 73/130 nt 8 8 X 8.8.X [1.17.9.X] null - No rearrangement found stop codons ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagccaccccaagatgggaacgtggtcgtcgcatgcctggtccaggcttcttccca +333 JY8QFUQ01DJ553 No results +334 JY8QFUQ01BLY2C No results +335 JY8QFUQ01CDHQA No results +336 JY8QFUQ01ALDHU No results +337 JY8QFUQ01AV95H No results +338 JY8QFUQ01DD7UW unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 449 67.91 146/215 nt 8 8 X 8.8.X [0.17.38.X] null + No rearrangement found stop codons Low V-REGION identity (67,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccagaaccggtgacggtgtcgtggaactcag +339 JY8QFUQ01DP56C No results +340 JY8QFUQ01DTAAY No results +341 JY8QFUQ01DPMM7 No results +342 JY8QFUQ01BETAF No results +343 JY8QFUQ01B3JPA No results +344 JY8QFUQ01B6YWG productive Homsap IGHV4-61*02 F 956 92.76 205/221 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD6-13*01 F 2 10 7 19 10.7.19 [1.17.38.11] CARETPKAAANSYSSYVMDVW in-frame + tctctggtggctccatcagtagtggtagttactactggagctggacccggcagcccgccgggaggggactggagtggattgggcgtgtccataacagtggtagttccaattacaagccctccctcacgagtcgagtcaccatattagtagacacgtccaagaatcagttctccctgaagctgacctccgtgaccgccgcagacacggccgtgtattactgtgcgagagaaacgcccaaggcagcagctaactcctacagctcttacgttatggacgtctggggccaagggaccacggtcaccgtcttctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +345 JY8QFUQ01DFHWB No results +346 JY8QFUQ01CVSSE No results +347 JY8QFUQ01BP11J No results +348 JY8QFUQ01BO0AK unknown (see comment) Homsap IGHV1-8*01 F (see comment) 399 65.42 140/214 nt 8 8 X 8.8.X [0.17.38.X] null + No rearrangement found stop codons Low V-REGION identity (65,42% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggaaacaccttcaccacttatgatatcaactgggtgcgacaggccactggacaagggcttgagtggatgggatggctgaaccctgacagtggtcacacaggctatgcacagaacttccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +349 JY8QFUQ01CXJI9 No results +350 JY8QFUQ01CMCF8 No results +351 JY8QFUQ01AZUKR No results +352 JY8QFUQ01CCVRD No results +353 JY8QFUQ01BUTJV No results +354 JY8QFUQ01BGV3T No results +355 JY8QFUQ01BVPUR unknown (see comment) Homsap IGHV3-52*01 P, or Homsap IGHV3-52*02 P or Homsap IGHV3-52*03 P or Homsap IGHV3-74*01 F or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 125 85.29 29/34 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found tctggatttaccttcagtaagttctggatgcatt +356 JY8QFUQ01AQQH4 No results +357 JY8QFUQ01CU1YS unknown (see comment) Homsap IGHV3-7*02 F 109 59.04 49/83 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +358 JY8QFUQ01C6R1U unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 140 78.26 36/46 nt 8 X X 8.X.X [1.6.X.X] null + No rearrangement found ctctggattcagcctcgccacttatagtatgagttgggtccgccag +359 JY8QFUQ01AFNDO No results +360 JY8QFUQ01DEJ4T No results +361 JY8QFUQ01BWHN8 No results +362 JY8QFUQ01CVRGF No results +363 JY8QFUQ01BR7JT No results +364 JY8QFUQ01DBTU5 No results +365 JY8QFUQ01DSRBO No results +366 JY8QFUQ01CRWD6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +367 JY8QFUQ01DNZXT No results +368 JY8QFUQ01DSPSC No results +369 JY8QFUQ01DPHDA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 393 87.25 89/102 nt 86.27 88/102 nt 8 8 X 8.8.X [1.15.1.X] null + No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 4 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) tctggattcacctttaatagctttgccatgagttgggtccgccagtcagggaggggctggagtgggtctcagccattagtggcagtggtagtcggacatatt +370 JY8QFUQ01CJKQL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 126 61.73 50/81 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttcccgcacagtcgacggtgtcgtggaactcag +371 JY8QFUQ01DCG2T No results +372 JY8QFUQ01DFQEL No results +373 JY8QFUQ01AEV0H No results +374 JY8QFUQ01ATH3X No results +375 JY8QFUQ01A1BVY No results +376 JY8QFUQ01DLH6V productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 839 86.88 192/221 nt 85.97 190/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARRHYGEGLFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 95 of V-REGION: 'N' (1 nucleotides at position 192 to 192 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 99 of V-REGION: 'T' (1 nucleotides at position 205 to 205 in the user submitted sequence), (cause frameshift); tctttggtggctccatcaccaataataattacttctggggctggatccgccagcccccagggaaggggctggagtggattggggatgtccagtatagtgggagcacctactccagcccgtccctcaagaggcgggtcaccatgtctgtggacgtgtccaaaagtcaggtctccctgagactgagctctgtgNaccgccacagacTacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggggcttcttcccccaa +377 JY8QFUQ01CGDOB unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 734 91.86 158/172 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found ctctggagtcacctttagtgactattggatgagctggatccgccaggctccagggaaggggccggagtgggtggccaacatagagcaagatgggagtgagataaattatgtggactctgtgaagggccgattcaccatctccagagacaacaccgagaatgcactgtatctg +378 JY8QFUQ01A0FTA No results +379 JY8QFUQ01BMCKP No results +380 JY8QFUQ01C32OL No results +381 JY8QFUQ01B4FU0 No results +382 JY8QFUQ01AY1UT No results +383 JY8QFUQ01DKHE4 No results +384 JY8QFUQ01AQJ6V No results +385 JY8QFUQ01B6N8I No results +386 JY8QFUQ01C3M6T No results +387 JY8QFUQ01DSQVV No results +388 JY8QFUQ01BWXFY No results +389 JY8QFUQ01BR779 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 471 94.29 99/105 nt 93.33 98/105 nt 8 8 X 8.8.X [1.16.1.X] null - No rearrangement found in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatacattagtaggagtagtactgacatatac +390 JY8QFUQ01COY2I No results +391 JY8QFUQ01B40WG No results +392 JY8QFUQ01BOBET No results +393 JY8QFUQ01CTE40 No results +394 JY8QFUQ01A7BCP unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F or Homsap IGHV7-81*01 ORF 138 59.05 62/105 nt 58.1 61/105 nt 8 8 X 8.8.X [0.16.2.X] null + No rearrangement found in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) cggttacattgttaccacctctggtttcagctgggtgcgacaggccctggacaaggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +395 JY8QFUQ01BHLHM No results +396 JY8QFUQ01DFGLR No results +397 JY8QFUQ01CRSMP No results +398 JY8QFUQ01DDODG No results +399 JY8QFUQ01C51RG unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 619 93.57 131/140 nt 92.86 130/140 nt 8 8 X 8.8.X [1.16.12.X] null + No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaagggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctc +400 JY8QFUQ01AWT70 No results +401 JY8QFUQ01DUGND No results +402 JY8QFUQ01C3JFU unknown (see comment) Homsap IGHV3-49*01 F, or Homsap IGHV3-49*03 F or Homsap IGHV3-49*05 F 83 51.54 67/130 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons tctggattcacctttggtgactatgctatgagctggttccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +403 JY8QFUQ01CQPF4 No results +404 JY8QFUQ01A9YCZ No results +405 JY8QFUQ01CLOT5 No results +406 JY8QFUQ01BC7U7 No results +407 JY8QFUQ01AV157 unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag +408 JY8QFUQ01B3JEK No results +409 JY8QFUQ01DKG75 No results +410 JY8QFUQ01AU5WK unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 467 70.92 139/196 nt 8 7 X 8.7.X [1.17.32.X] null + No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AU5WK ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (70,92% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +411 JY8QFUQ01DKO1R No results +412 JY8QFUQ01BOWEY No results +413 JY8QFUQ01CANUV No results +414 JY8QFUQ01BJQRL No results +415 JY8QFUQ01AOX45 No results +416 JY8QFUQ01DC5ET No results +417 JY8QFUQ01ALY4Y productive Homsap IGHV3-48*03 F, or Homsap IGHV3-48*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-74*03 F (see comment) 393 78.46 102/130 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 X 5 17 X.5.17 [X.X.38.11] CVRDSGPSGYARYESMDVW in-frame - Low V-REGION identity (78,46% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcagcctcacttcctatggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagtggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +418 JY8QFUQ01BBG0R No results +419 JY8QFUQ01C7G3C No results +420 JY8QFUQ01BEF8K No results +421 JY8QFUQ01BZX6I No results +422 JY8QFUQ01AZT9Z No results +423 JY8QFUQ01DJFJY No results +424 JY8QFUQ01AS5E1 No results +425 JY8QFUQ01A0QZV No results +426 JY8QFUQ01CQ9D6 No results +427 JY8QFUQ01BO8OD No results +428 JY8QFUQ01AFYA4 No results +429 JY8QFUQ01C1COE No results +430 JY8QFUQ01CXQPM No results +431 JY8QFUQ01DI9W4 No results +432 JY8QFUQ01CBZYI No results +433 JY8QFUQ01ANUSS No results +434 JY8QFUQ01BIKF1 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 652 89.51 145/162 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 X 7 11 X.7.11 [X.9.38.11] CVRHVRRFWFDPW in-frame - gagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +435 JY8QFUQ01CB5IP No results +436 JY8QFUQ01DLQOW No results +437 JY8QFUQ01CNVJN No results +438 JY8QFUQ01C3CZA No results +439 JY8QFUQ01DFRDQ No results +440 JY8QFUQ01AJKX6 No results +441 JY8QFUQ01DPZ2N No results +442 JY8QFUQ01A5M7E unknown (see comment) Homsap IGHV3-23*02 F, or Homsap IGHV3-23*03 F (see comment) 241 66.39 81/122 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found Low V-REGION identity (66,39% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagctttagcaactttgccatgacttgggtccgccaggctccagggaaggggctggagtgggtcccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +443 JY8QFUQ01CE24H No results +444 JY8QFUQ01AIQ17 unknown (see comment) Homsap IGHV3-22*01 P, or Homsap IGHV3-22*02 P 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons tgtctggattctccgtcagtttcaactacatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +445 JY8QFUQ01DK0QG No results +446 JY8QFUQ01BICC7 No results +447 JY8QFUQ01DQL67 No results +448 JY8QFUQ01BLB0P No results +449 JY8QFUQ01AN7ZY No results +450 JY8QFUQ01ARZSW No results +451 JY8QFUQ01A2N5I No results +452 JY8QFUQ01B8MWX No results +453 JY8QFUQ01A52H0 No results +454 JY8QFUQ01A24OC No results +455 JY8QFUQ01AZ6K0 No results +456 JY8QFUQ01CB16J No results +457 JY8QFUQ01AFUHA No results +458 JY8QFUQ01AQKLG No results +459 JY8QFUQ01AS1NJ No results +460 JY8QFUQ01AIIG0 No results +461 JY8QFUQ01DACF9 No results +462 JY8QFUQ01A1SWD No results +463 JY8QFUQ01B0WIV No results +464 JY8QFUQ01BA9X0 No results +465 JY8QFUQ01DN8SU No results +466 JY8QFUQ01AXCPB No results +467 JY8QFUQ01CUANZ No results +468 JY8QFUQ01BB6WW unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 993 96.26 206/214 nt 95.33 204/214 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.16.38.11] CARDNYGDY## out-of-frame + in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaagggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +469 JY8QFUQ01AG3W3 No results +470 JY8QFUQ01CPQER No results +471 JY8QFUQ01DTN1Y No results +472 JY8QFUQ01CY9NS No results +473 JY8QFUQ01DMY4I No results +474 JY8QFUQ01AJ09H No results +475 JY8QFUQ01BTYQ8 No results +476 JY8QFUQ01A408Y unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +477 JY8QFUQ01CFSDN No results +478 JY8QFUQ01C52OU No results +479 JY8QFUQ01CKAWP unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 487 83.94 115/137 nt 83.21 114/137 nt 8 8 X 8.8.X [1.16.12.X] null + No rearrangement found Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactca +480 JY8QFUQ01C9S8B unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 94 52.24 70/134 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +481 JY8QFUQ01C58WN unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 120 54.55 72/132 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons tctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +482 JY8QFUQ01DC64J unknown (see comment) Homsap IGHV3-11*01 F 882 89.86 195/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcactttcagtgactactacatgaattgggtccgccaggctccagggaagggcctggagtggctttcatacattactgcaagtggtgccatcatacactatgcagactctgtgaagggccgattcatcatctccagggacaacgccaagaactcactgtctctgcagatgaacagcctgagagccgacgacacggccgtctattattgtgctcgggggcaagggcaagggtggaactacctactaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +483 JY8QFUQ01DKRA1 unknown (see comment) Homsap IGHV4-31*06 F, or Homsap IGHV4-61*01 F or Homsap IGHV4-61*03 F or Homsap IGHV4-61*04 F 127 57.27 63/110 nt 10 7 X 10.7.X [1.17.1.X] null + No rearrangement found tctctggtgcctccgtcagcagtggtagtttctactggacctggattcgtcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +484 JY8QFUQ01A8ZYB No results +485 JY8QFUQ01DTNPF No results +486 JY8QFUQ01DRP22 No results +487 JY8QFUQ01AR674 No results +488 JY8QFUQ01DRSSU unknown (see comment) Homsap IGHV3-13*01 F (see comment) 355 67.65 115/170 nt 8 7 X 8.7.X [1.17.23.X] null + No rearrangement found stop codons Low V-REGION identity (67,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgctggattcaccctcagttcctacgacatgcactgggtccgccagactacaggaaaaggtctggagtgggtctcaggtataagcactgacggtgacacatactattcaggctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +489 JY8QFUQ01A72LA No results +490 JY8QFUQ01B9MV2 No results +491 JY8QFUQ01A8NUS No results +492 JY8QFUQ01ADSW9 No results +493 JY8QFUQ01DNO6S No results +494 JY8QFUQ01A77TK No results +495 JY8QFUQ01CJ228 No results +496 JY8QFUQ01AXNH6 No results +497 JY8QFUQ01AOMWB No results +498 JY8QFUQ01DTX5J productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +499 JY8QFUQ01ARHLG No results +500 JY8QFUQ01B476I No results +501 JY8QFUQ01DVKJP No results +502 JY8QFUQ01BYZ76 No results +503 JY8QFUQ01CYVVQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 822 87.38 187/214 nt 85.98 184/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKSVSSGWPIDEIDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'GA' (2 nucleotides at position 62 to 63 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 47 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggaggggcgtgGAgagtggtcatcagGccattagtggcagtggtagtcggacatattacgcagactccgtgaagggccggttcaccatctccagagacaagtccaagaaaacgttgtatctacaaatgaacagcctgagagccgaggacacggccactttctattgtgcgaagagtgtgagtagtggctggccgatcgacgaaattgactactggggccaggggacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +504 JY8QFUQ01DT7FQ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 904 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'GTC' (3 nucleotides at position 71 to 73 in the user submitted sequence), (do not cause frameshift); tctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggctgggagtgggGTCagtctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +505 JY8QFUQ01CWTEG No results +506 JY8QFUQ01C47A0 No results +507 JY8QFUQ01C2J7E No results +508 JY8QFUQ01C8OKN No results +509 JY8QFUQ01AG2Q1 No results +510 JY8QFUQ01DRK4R unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 170 58.65 78/133 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found tctggattcaccttcagcaaccataacatgaactgggtccgccaggctcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +511 JY8QFUQ01BL9TA No results +512 JY8QFUQ01CGZ96 No results +513 JY8QFUQ01BP11C unknown (see comment) Homsap IGHV3-72*01 F 119 54.62 71/130 nt 8 10 X 8.10.X [1.17.6.X] null + No rearrangement found stop codons cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +514 JY8QFUQ01BGOMP No results +515 JY8QFUQ01BMQFZ No results +516 JY8QFUQ01AE8A1 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 399 78.03 103/132 nt 75.76 100/132 nt 7 6 X 7.6.X [1.17.12.X] null + No rearrangement found Low V-REGION identity (78,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 78 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagctttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +517 JY8QFUQ01DHU4L unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 949 93.52 202/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaacctcag +518 JY8QFUQ01DVQHF productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 285 82.35 70/85 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame + Low V-REGION identity (82,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccta +519 JY8QFUQ01B65WE No results +520 JY8QFUQ01CXB1G No results +521 JY8QFUQ01BT6J3 No results +522 JY8QFUQ01CUUV5 No results +523 JY8QFUQ01DIF3I No results +524 JY8QFUQ01AFA56 No results +525 JY8QFUQ01CNA11 No results +526 JY8QFUQ01CSIVD No results +527 JY8QFUQ01CX5A6 No results +528 JY8QFUQ01BKEXQ No results +529 JY8QFUQ01AMJT2 No results +530 JY8QFUQ01C68TM No results +531 JY8QFUQ01BAOHD No results +532 JY8QFUQ01BRAT9 No results +533 JY8QFUQ01AKP6C unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + stop codons ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttagcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatcccctgaccagcccctaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +534 JY8QFUQ01A8HRS No results +535 JY8QFUQ01BKB83 unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F (see comment) 237 60.12 101/168 nt 8 8 X 8.8.X [0.17.22.X] null + No rearrangement found Low V-REGION identity (60,12% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcagcaactactatagacactgggtgcgacaggcccctggacaagggcttgagtggatgggaatgatcagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +536 JY8QFUQ01A4KPV unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 84 83.33 20/24 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found tctggattcagcgtcaacaacaac +537 JY8QFUQ01DE2KK unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 199 78.46 51/65 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found tctggattcagtttcagtacctatgcaatgcactgggtccgccaggctccagggcttcttccccc +538 JY8QFUQ01BGWW0 No results +539 JY8QFUQ01BALYU No results +540 JY8QFUQ01B3BH7 No results +541 JY8QFUQ01B2I04 No results +542 JY8QFUQ01CXHCH No results +543 JY8QFUQ01AD6ZM No results +544 JY8QFUQ01AZMNG No results +545 JY8QFUQ01A4K11 No results +546 JY8QFUQ01DQ3IY productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD3-10*01 F 1 8 8 19 8.8.19 [1.17.38.11] CARPAFLWFGDLPAEDGFDVW in-frame + tctggatacagctttaccaattactggatcggctgggtgcgccaggtgcccggaaaaggcctggagtggatggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcagtaccgcctaccttcagtggagcagtctagcgacctcggacaccgccatgtattactgtgcgagaccagcttttctctggttcggggacttaccggccgaggatggttttgatgtctggggccaaggaacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +547 JY8QFUQ01DQUSE productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 933 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt 8 10 7 8.10.7 [0.16.38.11] CTARNFDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift) ctggactcactttcaataacgcctggttgaactgggtccgccaggctccagggaagggactggagtggttggccatattaaacccgaggctgatggtgggacaacagactacaatgcacccgtgaaaggcagattcaccatctcaagagatgtttcagcaaacacgctgtatctgcaaatgaacagcctgaaaaccgaagacacagccgtctattactgtaccgcaagaaactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +548 JY8QFUQ01CU1FT No results +549 JY8QFUQ01CVRCR No results +550 JY8QFUQ01BSAFV No results +551 JY8QFUQ01DN9PB productive Homsap IGHV4-61*03 F 152 66.25 53/80 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 1 X X 13 X.X.13 [X.X.26.11] CATVRHLGERIFDFW in-frame + tctctggggccaccatgagtagtttctactggagctggctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +552 JY8QFUQ01A01FG No results +553 JY8QFUQ01BG9CW No results +554 JY8QFUQ01C9E33 No results +555 JY8QFUQ01C16F0 unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 135 77.78 35/45 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found ctctggattcagcctcgccacttatagtatgagttgggtccgcca +556 JY8QFUQ01ALN7Q No results +557 JY8QFUQ01DEYBF No results +558 JY8QFUQ01ANDSC No results +559 JY8QFUQ01CTY7U unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +560 JY8QFUQ01AMU1R unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag +561 JY8QFUQ01CU2L0 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 161 57.89 77/133 nt 8 6 X 8.6.X [1.17.11.X] null - No rearrangement found stop codons cctctggatacagttttaacagttatgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +562 JY8QFUQ01DOXZT No results +563 JY8QFUQ01CSG56 No results +564 JY8QFUQ01AIB60 No results +565 JY8QFUQ01CP7Q3 No results +566 JY8QFUQ01B48ZH No results +567 JY8QFUQ01DRKWV No results +568 JY8QFUQ01DQ4YE No results +569 JY8QFUQ01CVXN6 No results +570 JY8QFUQ01A56PJ No results +571 JY8QFUQ01BEZLP No results +572 JY8QFUQ01DO88X unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD3-16*02 F 3 8 7 X 8.7.X [1.17.38.11] CARAPGWMNPFDF## out-of-frame + tctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggccactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccgag +573 JY8QFUQ01BFHP5 No results +574 JY8QFUQ01CM61C No results +575 JY8QFUQ01A23JI No results +576 JY8QFUQ01DUGFP No results +577 JY8QFUQ01BLTM8 No results +578 JY8QFUQ01AHNAT No results +579 JY8QFUQ01ASTJ6 No results +580 JY8QFUQ01B1ZDH No results +581 JY8QFUQ01A6IGF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt 85.65 185/216 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.37.11] CVKEDHDSGLRVLLEW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 160 in the user submitted sequence), (cause frameshift) ctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggaggggcgtggagGtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +582 JY8QFUQ01AS1KI No results +583 JY8QFUQ01AI3IO No results +584 JY8QFUQ01C2SB7 No results +585 JY8QFUQ01AEO3Z No results +586 JY8QFUQ01B5XEH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 677 95.3 142/149 nt 94.63 141/149 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 1 8 8.1.8 [1.1.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01B5XEH ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 40 of V-REGION: 68 nucleotides (from position 33 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtagctactggatgcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa +587 JY8QFUQ01DOON7 No results +588 JY8QFUQ01AQYNY No results +589 JY8QFUQ01CMHYY No results +590 JY8QFUQ01CWE8D No results +591 JY8QFUQ01BO5WL No results +592 JY8QFUQ01AIZZR No results +593 JY8QFUQ01C9ZRF No results +594 JY8QFUQ01DE8IY No results +595 JY8QFUQ01AVNLI unknown (see comment) Homsap IGHV3-11*01 F (see comment) 618 76.78 162/211 nt 8 7 X 8.7.X [0.17.38.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AVNLI ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (76,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +596 JY8QFUQ01C2VVV No results +597 JY8QFUQ01B9Z61 No results +598 JY8QFUQ01ACK6B No results +599 JY8QFUQ01DLUGR No results +600 JY8QFUQ01DS5HR No results +601 JY8QFUQ01DRGVP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD4-11*01 ORF 3 8 8 17 8.8.17 [0.17.38.11] CAREVTRLTVPYYLYFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); cggattcacctttagtagttactggatgcactgggtccgccAaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagcctgagagccggggacacggctgtttattattgtgcaagagaggtgactagacttactgtcccctattacttatacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +602 JY8QFUQ01AHMRK No results +603 JY8QFUQ01AS4U6 No results +604 JY8QFUQ01DNYZ7 No results +605 JY8QFUQ01B7I0E No results +606 JY8QFUQ01C745G No results +607 JY8QFUQ01C7EWY No results +608 JY8QFUQ01C3IZ7 No results +609 JY8QFUQ01CR0HB No results +610 JY8QFUQ01CJ4IC No results +611 JY8QFUQ01BOBV7 No results +612 JY8QFUQ01BL2KM No results +613 JY8QFUQ01DKFYD No results +614 JY8QFUQ01CPNL9 No results +615 JY8QFUQ01A6WTE No results +616 JY8QFUQ01AMNJH No results +617 JY8QFUQ01BAUWF No results +618 JY8QFUQ01A6T2J No results +619 JY8QFUQ01AJ0OS No results +620 JY8QFUQ01BKBGF No results +621 JY8QFUQ01DB108 No results +622 JY8QFUQ01B7YYU No results +623 JY8QFUQ01BBASZ No results +624 JY8QFUQ01BQWDF No results +625 JY8QFUQ01AO955 No results +626 JY8QFUQ01AHDUP No results +627 JY8QFUQ01CSEK4 No results +628 JY8QFUQ01C2E4Q No results +629 JY8QFUQ01A0CIX No results +630 JY8QFUQ01B1FJP No results +631 JY8QFUQ01A46LO No results +632 JY8QFUQ01ASMJE productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'AG' (2 nucleotides at position 73 to 74 in the user submitted sequence), (cause frameshift); tctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggctgggagtgggtcAGtctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +633 JY8QFUQ01DOJG4 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 701 80.47 173/215 nt 80.0 172/215 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found Low V-REGION identity (80,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactca +634 JY8QFUQ01DI7CS unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 420 76.19 112/147 nt 8 7 X 8.7.X [1.17.15.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DI7CS ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (76,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtctgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactacttccccgaaccggtgacggtgtcgtggaactc +635 JY8QFUQ01BN181 No results +636 JY8QFUQ01DJYKG No results +637 JY8QFUQ01B28X1 No results +638 JY8QFUQ01AS1KQ No results +639 JY8QFUQ01CZDB6 No results +640 JY8QFUQ01CIKOL No results +641 JY8QFUQ01BUDPR unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +642 JY8QFUQ01DBTI3 unknown (see comment) Homsap IGHV3-74*03 F 108 50.79 96/189 nt 8 8 X 8.8.X [1.17.28.X] null + No rearrangement found stop codons ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +643 JY8QFUQ01CVVLT No results +644 JY8QFUQ01DP6R4 No results +645 JY8QFUQ01C8AIG No results +646 JY8QFUQ01A6HYZ unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 106 59.74 46/77 nt 58.44 45/77 nt 7 X X 7.X.X [1.17.X.X] null + No rearrangement found in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) tctggattcacgttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +647 JY8QFUQ01BAHEK No results +648 JY8QFUQ01DV2ZV No results +649 JY8QFUQ01C6PBL No results +650 JY8QFUQ01B5TWP No results +651 JY8QFUQ01AQLGT No results +652 JY8QFUQ01BBQ0C No results +653 JY8QFUQ01A82YB No results +654 JY8QFUQ01CT128 No results +655 JY8QFUQ01ANLP4 No results +656 JY8QFUQ01DJ71O No results +657 JY8QFUQ01DAI4Z No results +658 JY8QFUQ01A698F productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDREDSSGYYFFRDGFDIW in-frame + ctctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctccggtattggtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagatcgtgaagatagtagtggttattacttcttccgtgatggttttgatatttggggccaagggacaatggtcaccgtctcttcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttc +659 JY8QFUQ01AH6JY unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 805 86.11 186/216 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDPGNYWGYYYDS## out-of-frame + tctggattcacctttagtgattatgccttgagctgggtccgccagactcccgggaaggggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgagagatccgggaaattattggggatactattatgactcttggggcctggggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +660 JY8QFUQ01DSHN9 No results +661 JY8QFUQ01CVWH1 No results +662 JY8QFUQ01A9PO9 No results +663 JY8QFUQ01AU9D7 No results +664 JY8QFUQ01DA2A8 No results +665 JY8QFUQ01CSODU No results +666 JY8QFUQ01CMCU9 No results +667 JY8QFUQ01DU4DT No results +668 JY8QFUQ01CS1QJ No results +669 JY8QFUQ01DTA61 No results +670 JY8QFUQ01DAXBN No results +671 JY8QFUQ01CY465 No results +672 JY8QFUQ01B154Q productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 853 87.39 194/222 nt 86.94 193/222 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-22*01 F 2 8 10 11 8.10.11 [1.17.37.11] CTWDSTGYFRLTW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 80 of V-REGION: 1 nucleotides (from position 150 in the user submitted sequence), (cause frameshift) ctctggactcactttcagtgacgcctggatgacctgggtccgccaggttccagggaaggggctggagtgggttgcccatattagatggaactctgatgactggaccacagactacgctactcccgtgaagggcagattcaccatctcaaagatatttcagagaacacgctgtatctacaaatgaacagcctgataagcgaggatacaggcgtttattactgtacctgggacagcactggttattttcggcttacctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +673 JY8QFUQ01BLGF2 No results +674 JY8QFUQ01BOMJ1 productive Homsap IGHV3-23*05 F (see comment) 447 83.08 108/130 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 X 5 16 X.5.16 [X.X.38.11] CVRYDYSRLHRSNYFGPW in-frame + Low V-REGION identity (83,08% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcatcagttatgactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaacgataggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +675 JY8QFUQ01DR1HV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt 86.18 187/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKYVEGWSYTGGLL##SYAMDVW out-of-frame + in FR2-IMGT at codon 51 of V-REGION: 'A' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'AC' (2 nucleotides at position 117 to 118 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'TC' (2 nucleotides at position 157 to 158 in the user submitted sequence), (cause frameshift); ttctggattcgcctttagccgttatgccatgacttgggtccgccagactccagggaggggcgtggaAgtgggtctAcaggtctcagtggtagtggtgatagcacatactactcaaaACctccgtgaagggccggttcatcatcttcagagacaattTCcaaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggaggggtggtcatatacggggggcctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccatggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactca +676 JY8QFUQ01DW425 unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 180 53.7 116/216 nt 8 8 X 8.8.X [1.17.37.X] null + No rearrangement found gtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctgcctccaccaagggcccatcggtcttcccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +677 JY8QFUQ01CWGVS No results +678 JY8QFUQ01COA86 No results +679 JY8QFUQ01BLQBF No results +680 JY8QFUQ01DD2I0 No results +681 JY8QFUQ01CVQ5V productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcatctttgatgattttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +682 JY8QFUQ01CEUZZ No results +683 JY8QFUQ01CM1RQ No results +684 JY8QFUQ01C3RZV unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found agttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag +685 JY8QFUQ01C1MVU No results +686 JY8QFUQ01CWP9S No results +687 JY8QFUQ01CJ7U8 No results +688 JY8QFUQ01C74EW unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found ctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgaaccggtgacggtgtcgtggaactcag +689 JY8QFUQ01CV1KZ No results +690 JY8QFUQ01DOW2U No results +691 JY8QFUQ01DFFIC No results +692 JY8QFUQ01A9SLL No results +693 JY8QFUQ01C7H18 productive (see comment) Homsap IGHV3-7*01 F 895 90.74 196/216 nt 89.35 193/216 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD4-23*01 ORF 3 8 8 12 8.8.12 [1.17.38.11] CARGTSVDPGIDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 49 of V-REGION: 'C' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); tctggattcacctttagtaattattggatgcactgggtccgccaggtttcagggaggggCgctggagtgcgtggccaccataaacgaagatggaagtgaGgagacactatgtggacCtctgtgaagggccgattcaccgtctccagagacaacgccaagaactctctgtttttgcagatgaacagcctgagagccgaggacacggctgtctactactgtgcgagagggacctcagtggacccggggattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +694 JY8QFUQ01DI6GR No results +695 JY8QFUQ01AQS6J No results +696 JY8QFUQ01CW9LP No results +697 JY8QFUQ01DTOEH unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 348 86.02 80/93 nt 8 5 X 8.5.X [1.17.X.X] null + No rearrangement found tctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc +698 JY8QFUQ01CDT9Z No results +699 JY8QFUQ01B98W0 No results +700 JY8QFUQ01BJQT2 No results +701 JY8QFUQ01ADSZU No results +702 JY8QFUQ01CJAZY No results +703 JY8QFUQ01A0EHO No results +704 JY8QFUQ01DNR43 unknown (see comment) Homsap IGHV3-7*02 F (see comment) 232 57.73 112/194 nt 57.22 111/194 nt 8 8 X 8.8.X [1.16.31.X] null + No rearrangement found stop codons Low V-REGION identity (57,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaagggctggagtgggtggccaacataatgccagatggagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggcaacgtggtcgtcgcatgcctggtccagggcttcttcccccga +705 JY8QFUQ01CMW7Z No results +706 JY8QFUQ01CFB7L No results +707 JY8QFUQ01CE97L unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 109 60.81 45/74 nt 59.46 44/74 nt 7 X X 7.X.X [0.16.X.X] null + No rearrangement found in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift) ctggattcacgttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccaggcttcttcccca +708 JY8QFUQ01A8IAU No results +709 JY8QFUQ01DQ5TX No results +710 JY8QFUQ01CXXJ4 No results +711 JY8QFUQ01DXEL1 No results +712 JY8QFUQ01A9YYE unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F (see comment) 212 81.25 52/64 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found Low V-REGION identity (81,25% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagtttcagtacctatgcaatgcactgggtccgccaggctccagggcttcttccc +713 JY8QFUQ01AM6FE No results +714 JY8QFUQ01AIR6K No results +715 JY8QFUQ01AO1H5 No results +716 JY8QFUQ01BXGUS No results +717 JY8QFUQ01BF84M No results +718 JY8QFUQ01C5HO3 No results +719 JY8QFUQ01BG2IK No results +720 JY8QFUQ01CF2BM unknown (see comment) Homsap IGHV3-7*03 F (see comment) 706 80.56 174/216 nt 80.09 173/216 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found Low V-REGION identity (80,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctttaataactattggatgacatgggtccgccaggctccagggaagggctggagttggtggccaacataaagcaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +721 JY8QFUQ01CUHH5 unknown (see comment) Homsap IGHV3-66*02 F 743 92.44 159/172 nt 91.86 158/172 nt 8 7 X 8.7.X [4.16.21.X] null + No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) tctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaagggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgta +722 JY8QFUQ01DDJCP No results +723 JY8QFUQ01BCVWS No results +724 JY8QFUQ01DK9N6 unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 638 94.41 135/143 nt 93.01 133/143 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 160 80.0 40/50 nt Homsap IGHD3-16*01 F 3 7 X X 7.X.X [1.8.30.11] CARRDVGLH#FDLW out-of-frame + in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 72 nucleotides (from position 53 in the user submitted sequence), (do not cause frameshift) tctggatccaatttaactacgactggatcggctgggtgcgccagatgcccggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgctttgatctgtggggccaggggacaatggtcagcgtctcttcagcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +725 JY8QFUQ01DVXK9 No results +726 JY8QFUQ01CZDNQ No results +727 JY8QFUQ01CZFR8 No results +728 JY8QFUQ01C8TM1 No results +729 JY8QFUQ01DGT7R No results +730 JY8QFUQ01BAPJQ No results +731 JY8QFUQ01BZK37 No results +732 JY8QFUQ01BE8EU No results +733 JY8QFUQ01BJ1X4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + tctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +734 JY8QFUQ01A91H2 productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAYFSTGYW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +735 JY8QFUQ01B7U2A No results +736 JY8QFUQ01DAT0N No results +737 JY8QFUQ01DR2ZT productive (see comment) Homsap IGHV1-2*02 F (see comment) 777 84.58 181/214 nt 83.64 179/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARGLSYDSSPYWGYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); tggatacatcttcaatgacttctacatatattgggtgcgacaGggcccctggacaagGggcttgagtggatgggatggttcaaccctaatagtcgtgtcacagactatgcagagaaatttcagggcagggtcaccatgaccggggacccgtcccgcagcacagtccacctgaaactgacccgcctgaagtcggacgacacggccgtctattactgcgcgagaggtctctcctatgacagtagtccttattggggctactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +738 JY8QFUQ01C2RD7 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +739 JY8QFUQ01BBT7W No results +740 JY8QFUQ01ARSEU No results +741 JY8QFUQ01B3E3Q No results +742 JY8QFUQ01AJBL2 No results +743 JY8QFUQ01BG4HV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1012 96.76 209/216 nt 96.3 208/216 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.16.38.11] CAKSLYNSSPYYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacaactatgccatgaactgggtccgccaggctccagggaagggctggagtgggtctcatctattagtggtagtattagtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagagcttatataacagcagcccctactactttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaaggggccccatcggtcttcccctggcgccctgctccaggagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +744 JY8QFUQ01BZSLD No results +745 JY8QFUQ01BY3XK No results +746 JY8QFUQ01DW1LD No results +747 JY8QFUQ01A46E5 No results +748 JY8QFUQ01DAQTU No results +749 JY8QFUQ01CPRYN No results +750 JY8QFUQ01CUKXW No results +751 JY8QFUQ01C23RC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggcctgcctggtcaaggactatttccccgaaccggtgacggtgtcgtggaactcag +752 JY8QFUQ01C5MT6 No results +753 JY8QFUQ01BCER9 No results +754 JY8QFUQ01BJ9FO No results +755 JY8QFUQ01AZDYV No results +756 JY8QFUQ01C8T1H No results +757 JY8QFUQ01DL1WJ No results +758 JY8QFUQ01CA1LA No results +759 JY8QFUQ01DVPSG unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F (see comment) 266 57.8 126/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (57,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +760 JY8QFUQ01CR15T No results +761 JY8QFUQ01B51MO No results +762 JY8QFUQ01CLAUP No results +763 JY8QFUQ01BECNO No results +764 JY8QFUQ01B4THL unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 487 89.92 107/119 nt 88.24 105/119 nt 8 8 X 8.8.X [1.17.5.X] null - No rearrangement found in CDR1-IMGT at codon 28 of V-REGION: 'GT' (2 nucleotides at position 9 to 10 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); cctctggaGTtcagccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtCagtagtgacatatactacgcagaccca +765 JY8QFUQ01BUAXD No results +766 JY8QFUQ01CJS8T No results +767 JY8QFUQ01C24AK No results +768 JY8QFUQ01ATJUK No results +769 JY8QFUQ01DCOU8 No results +770 JY8QFUQ01BEP2R No results +771 JY8QFUQ01C0COZ No results +772 JY8QFUQ01BM1D1 No results +773 JY8QFUQ01CDNFM No results +774 JY8QFUQ01BU5NL productive Homsap IGHV3-66*02 F 858 89.25 191/214 nt Homsap IGHJ1*01 F 201 86.54 45/52 nt Homsap IGHD6-19*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAAVGVGSAVSFQYW in-frame + ctctggcttcaccgtcaataacaactacatgggctgggtccgccaggctccagggaaggggctggagtgggtctcgattatttattacggtggaaccacatattacgctgactccgtgaagggccgattcaccatctctagagacacctccaagaacacgttatttcttcaaatgaataccctaagaggtgaggacacggctgtgtactactgtgcggcagtcggagtgggaagtgcagtctccttccaatactggggccagggcaccctggtcaccgtctcctnagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +775 JY8QFUQ01DHHI6 No results +776 JY8QFUQ01BU7OF No results +777 JY8QFUQ01A6ZWI productive Homsap IGHV3-21*04 F 483 89.26 108/121 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 X 2 10 X.2.10 [X.X.38.11] CARAVSNQVDVW in-frame - ctctggattcgccttcaactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagccaccccaagatgggaacgtggtcgtcgcatgcctggtccaggcgttcttccccca +778 JY8QFUQ01A6Q2P No results +779 JY8QFUQ01CGWP9 unknown (see comment) Homsap IGHV3-48*02 F 895 90.28 195/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +780 JY8QFUQ01DHZ6E No results +781 JY8QFUQ01B9W2W No results +782 JY8QFUQ01BNHH9 No results +783 JY8QFUQ01CM6DN unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 559 78.57 143/182 nt 8 8 X 8.8.X [1.17.26.X] null + No rearrangement found Low V-REGION identity (78,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccgaaccggtgacggtgtcgtggaactcag +784 JY8QFUQ01DEPC1 No results +785 JY8QFUQ01CHUDH No results +786 JY8QFUQ01AGUL6 No results +787 JY8QFUQ01A85PF No results +788 JY8QFUQ01BUK3U No results +789 JY8QFUQ01BREWM No results +790 JY8QFUQ01C664S productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 952 92.34 205/222 nt 91.89 204/222 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.37.11] CTHLREEMSYEW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 161 in the user submitted sequence), (cause frameshift) ctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +791 JY8QFUQ01A6Y9U unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 99 52.59 71/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +792 JY8QFUQ01DSWAV No results +793 JY8QFUQ01DVBVI No results +794 JY8QFUQ01CDWXY No results +795 JY8QFUQ01BEZNM unknown (see comment) Homsap IGHV1-2*01 F, or Homsap IGHV1-2*05 F 597 94.7 125/132 nt 8 8 X 8.8.X [0.17.10.X] null + No rearrangement found tggatacaccttcaccaactactatcttcactgggtgcgacaggcccccggacaagggcttgagtggatgggacggatcaacccaaacagtggtggcacaacctatgcacagaagtttcagggcagggtcac +796 JY8QFUQ01BGZ27 No results +797 JY8QFUQ01DVSPM No results +798 JY8QFUQ01DBYSE No results +799 JY8QFUQ01BV7PO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +800 JY8QFUQ01DV0AR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 938 91.86 203/221 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [2.17.38.11] CASDLGGQKSYW in-frame - cagcctcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +801 JY8QFUQ01B9V81 No results +802 JY8QFUQ01C3S4F No results +803 JY8QFUQ01AZ3CP No results +804 JY8QFUQ01DUGYW No results +805 JY8QFUQ01AT8P8 No results +806 JY8QFUQ01DU4WR No results +807 JY8QFUQ01C8EOC No results +808 JY8QFUQ01CDEJP No results +809 JY8QFUQ01A4K8H No results +810 JY8QFUQ01DWME3 productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +811 JY8QFUQ01A4GQ1 No results +812 JY8QFUQ01DJIGF No results +813 JY8QFUQ01C2YDZ No results +814 JY8QFUQ01BLWTN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 87.61 191/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found cctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +815 JY8QFUQ01CJA85 No results +816 JY8QFUQ01AK99H No results +817 JY8QFUQ01AYY6J No results +818 JY8QFUQ01DAHAR No results +819 JY8QFUQ01C0TX2 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + tctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +820 JY8QFUQ01BDZZ6 No results +821 JY8QFUQ01AHM5M No results +822 JY8QFUQ01DTVIZ No results +823 JY8QFUQ01DBUHS unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +824 JY8QFUQ01DFSIO No results +825 JY8QFUQ01B6DKH No results +826 JY8QFUQ01B2GPJ No results +827 JY8QFUQ01A4NJN No results +828 JY8QFUQ01BIILY No results +829 JY8QFUQ01DQURD No results +830 JY8QFUQ01DTIAX No results +831 JY8QFUQ01BD2DM No results +832 JY8QFUQ01BFWOX No results +833 JY8QFUQ01BGN4A No results +834 JY8QFUQ01CSDSK No results +835 JY8QFUQ01C20Y3 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 102 53.03 70/132 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons tctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +836 JY8QFUQ01B4MJJ No results +837 JY8QFUQ01DDOJR unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.37.11] CVSDLAGQKGF# out-of-frame + in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 169 in the user submitted sequence), (cause frameshift) cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +838 JY8QFUQ01DEXOG No results +839 JY8QFUQ01BRI4Q unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 270 92.06 58/63 nt 8 X X 8.X.X [1.12.X.X] null - No rearrangement found tctggattcaccttcagcagctatagaatgaactgggtccgccaggctccagggaagggctgg +840 JY8QFUQ01ANOKI No results +841 JY8QFUQ01DUH2N No results +842 JY8QFUQ01BUA86 No results +843 JY8QFUQ01AE460 No results +844 JY8QFUQ01DQHKE No results +845 JY8QFUQ01A47P0 unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag +846 JY8QFUQ01AV8WH No results +847 JY8QFUQ01A1PUU No results +848 JY8QFUQ01BTDHW unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 124 54.55 72/132 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons tctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacntggtcatcgcctgcctggtccagggcttcttccccc +849 JY8QFUQ01C8V09 unknown (see comment) Homsap IGHV1-8*01 F 601 95.42 125/131 nt 8 8 X 8.8.X [0.17.10.X] null + No rearrangement found tggatacaccttcaccaattatgatatcaactgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaaaattggaaacacaggctctgcgcagaagttccagggcagagtca +850 JY8QFUQ01ASXZF unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 97 52.67 69/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons tctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +851 JY8QFUQ01DWSB4 No results +852 JY8QFUQ01BF7KJ unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F or Homsap IGHV1-69*01 F or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F 86 57.53 42/73 nt 56.16 41/73 nt X X X X.X.X [24.X.X.X] null - No rearrangement found in FR1-IMGT, from codon 7 of V-REGION: 3 nucleotides (from position 90 in the user submitted sequence), (do not cause frameshift) gagttccacgacaccgtcaccggttcgggaagtagtccttgaccaggcagcccagggccgctgtgctctcggaggtgctcctggagcagggcgccagggggaagaccgatgggcccttggtggaggtgacgaagccaccagaga +853 JY8QFUQ01ALKXU No results +854 JY8QFUQ01B41VG No results +855 JY8QFUQ01CE30D No results +856 JY8QFUQ01CJ6LP No results +857 JY8QFUQ01BL52H unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F or Homsap IGHV7-81*01 ORF 139 58.88 63/107 nt 8 8 X 8.8.X [0.17.2.X] null - No rearrangement found cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +858 JY8QFUQ01DPFUD No results +859 JY8QFUQ01BF4SK unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcatcttcagtagctactggatgcactggg +860 JY8QFUQ01BUIHI unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 671 78.44 171/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (78,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactatttccccgaaccggtgacggtgtcgtggaactcag +861 JY8QFUQ01A8AU3 No results +862 JY8QFUQ01BBWG2 No results +863 JY8QFUQ01BG99N unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 328 71.64 96/134 nt 70.9 95/134 nt 7 8 X 7.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (71,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) cctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaacggtgacggtgtcgtggaactcag +864 JY8QFUQ01CUU12 No results +865 JY8QFUQ01DV41N No results +866 JY8QFUQ01AKQLX No results +867 JY8QFUQ01DOBQP unproductive (see comment) Homsap IGHV4-59*10 F (see comment) 266 57.8 126/218 nt 57.34 125/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [3.17.37.X] null + stop codons no junction found The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01DOBQP ; 8 AA in Homsap_IGHV4-59*10), and low V-REGION identity (57,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT at codon 75 of V-REGION: 'C' (1 nucleotides at position 138 to 138 in the user submitted sequence), (cause frameshift); tccagtggcattgttaatggcgaaggtttggtcgtttctactggaactgggtccggcagatcgacgggcaggggctagagtggatcgggcgtgtttatcgtgatgggatcacaaactacaatccctccttcgggactCctggtcaccgtctcatctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +868 JY8QFUQ01CKWZR unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 643 77.31 167/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (77,31% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactatttccccgaaccggtgacggtgtcgtggaactcag +869 JY8QFUQ01DTX30 No results +870 JY8QFUQ01A1RCR No results +871 JY8QFUQ01CQ01A No results +872 JY8QFUQ01C5X6U unknown (see comment) Homsap IGHV3-66*03 F (see comment) 480 69.16 148/214 nt 68.69 147/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found stop codons Low V-REGION identity (69,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'TATGACTT' (8 nucleotides at position 83 to 90 in the user submitted sequence), (cause frameshift); ctctgggctcaccgtcagttacaactatttgacctgggtccgccaggcaccagggaaggggccggagtgagtctcacttattTATGACTTtataactgtggtaatacatactacgcagactccgtgaagggccgattcaccatctccagagacagggttcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +873 JY8QFUQ01DEX2B No results +874 JY8QFUQ01B7PLT No results +875 JY8QFUQ01CDZ1V No results +876 JY8QFUQ01B783U unknown (see comment) Homsap IGHV4-34*04 F, or Homsap IGHV4-34*07 F 102 53.03 70/132 nt 8 7 X 8.7.X [1.17.10.X] null + No rearrangement found gtctggtgagtccttcagtggttactactggagttggatccgccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +877 JY8QFUQ01CMDBC No results +878 JY8QFUQ01C2Q34 No results +879 JY8QFUQ01COLPI unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +880 JY8QFUQ01DO6FK No results +881 JY8QFUQ01CE65R unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-7*02 F 100 57.83 48/83 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +882 JY8QFUQ01BV5VD No results +883 JY8QFUQ01B91NW No results +884 JY8QFUQ01DXAE5 No results +885 JY8QFUQ01CJXCD No results +886 JY8QFUQ01DNNHI unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 119 57.28 59/103 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons ctctggattcaccttcagtcgttatagcatgaactgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +887 JY8QFUQ01AQBRP No results +888 JY8QFUQ01A5VGI No results +889 JY8QFUQ01C62I8 No results +890 JY8QFUQ01A5MLI unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 460 81.75 112/137 nt 81.02 111/137 nt 8 8 X 8.8.X [1.16.12.X] null + No rearrangement found Low V-REGION identity (81,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 33 in the user submitted sequence), (cause frameshift) tctggattcacctttaacagccatgccatgagttggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactca +891 JY8QFUQ01DVTUN No results +892 JY8QFUQ01DDYI9 No results +893 JY8QFUQ01A0ZHQ No results +894 JY8QFUQ01ACF7S productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame + tctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +895 JY8QFUQ01BHB8R No results +896 JY8QFUQ01CTM8X No results +897 JY8QFUQ01BSF5D No results +898 JY8QFUQ01CUDPM No results +899 JY8QFUQ01DUU48 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 895 90.74 196/216 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + tctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcttcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +900 JY8QFUQ01A9D8P No results +901 JY8QFUQ01CWDUG No results +902 JY8QFUQ01AP21K No results +903 JY8QFUQ01DS3Y4 No results +904 JY8QFUQ01AX9HH No results +905 JY8QFUQ01BK6NF productive Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-33*03 F (see comment) 379 80.0 96/120 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 X 2 17 X.2.17 [X.X.38.11] CAKDTITMGGDVAPLFDYW in-frame + Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttaactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +906 JY8QFUQ01C4K4T No results +907 JY8QFUQ01DG5GN No results +908 JY8QFUQ01AY698 No results +909 JY8QFUQ01B7E47 No results +910 JY8QFUQ01DQIR0 No results +911 JY8QFUQ01DFD3I unknown (see comment) Homsap IGHV1-NL1*01 P 90 56.79 46/81 nt 2 X X 2.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagagac +912 JY8QFUQ01AZ1G9 No results +913 JY8QFUQ01A9W1A No results +914 JY8QFUQ01DTQ02 productive Homsap IGHV3-7*01 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [2.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame - gcctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +915 JY8QFUQ01C9DSU No results +916 JY8QFUQ01A7FQQ No results +917 JY8QFUQ01BKVJZ No results +918 JY8QFUQ01CW6SK unknown (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 882 89.86 195/217 nt Homsap IGHJ5*02 F (see comment) 32 63.16 12/19 nt 8 8 X 8.8.X [1.17.38.0] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaccttcagtcgctatggcatgcactgggtccgccaggctccagggaaggggctggcatgggtttcatacattagtgccagtagcagcaccaagtactacgcaaattctctgaagggccggttcaccatctccagagacaacgccaagaattcactgtatctggaaatcaacagcctgagcgacgaggacacgtctgtgtattactgtgcgcgagatgactacggcttcttccccca +919 JY8QFUQ01AJBY4 No results +920 JY8QFUQ01B2UQO unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 80 80.0 20/25 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found tctggattcagcgtcaacaacaaca +921 JY8QFUQ01DCQ3Y No results +922 JY8QFUQ01BNSHZ unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F (see comment) 368 64.39 132/205 nt 63.9 131/205 nt 8 7 X 8.7.X [1.17.34.X] null - No rearrangement found Low V-REGION identity (64,39% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +923 JY8QFUQ01C31LE No results +924 JY8QFUQ01B19XO No results +925 JY8QFUQ01C2606 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F (see comment) 449 72.47 129/178 nt 71.91 128/178 nt 8 8 X 8.8.X [1.16.25.X] null + No rearrangement found Low V-REGION identity (72,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaagggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +926 JY8QFUQ01BEGQ1 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 91 52.34 67/128 nt 8 8 X 8.8.X [1.17.8.X] null + No rearrangement found stop codons tctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +927 JY8QFUQ01BK3H5 No results +928 JY8QFUQ01CV45O unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 634 77.31 167/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (77,31% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaaggtcttcccgctgagcctcgacagcaccccacagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +929 JY8QFUQ01BF1LO unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 119 54.62 71/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +930 JY8QFUQ01DKYKH unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-9*01 F or Homsap IGHV3-9*03 F 158 71.88 46/64 nt 70.31 45/64 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found in FR2-IMGT at codon 43 of V-REGION: 'CGC' (3 nucleotides at position 41 to 43 in the user submitted sequence), (do not cause frameshift); ctctggattccggtttgatgattatgccatacattgggttCGCctgcctggtccagggcttcttccc +931 JY8QFUQ01A1MA8 No results +932 JY8QFUQ01AJHU4 No results +933 JY8QFUQ01B4M1X No results +934 JY8QFUQ01DTX7W productive Homsap IGHV3-7*01 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [2.17.38.11] CAGGRGWLIDYW in-frame - gcctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +935 JY8QFUQ01ARIT8 No results +936 JY8QFUQ01CGVGC No results +937 JY8QFUQ01CS4OH No results +938 JY8QFUQ01B6UMA unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 245 58.55 113/193 nt 8 8 X 8.8.X [1.17.30.X] null - No rearrangement found Low V-REGION identity (58,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +939 JY8QFUQ01BAZV6 No results +940 JY8QFUQ01AWSFJ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 432 77.78 112/144 nt 8 8 X 8.8.X [1.17.13.X] null + No rearrangement found Low V-REGION identity (77,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctacgtggtcgtcgcatgcctggtccagggcttcttccc +941 JY8QFUQ01AG4YS No results +942 JY8QFUQ01DP7OF No results +943 JY8QFUQ01BC5DI unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F (see comment) 300 73.91 85/115 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-26*01 F 3 X 0 13 X.0.13 [X.X.38.11] CARFSGSYKSAFDIW in-frame - stop codons Low V-REGION identity (73,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctgaagatctcctgtaaggggttctggatacatctttaccgaccagtccatcaccaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagattcagtgggagttacaaatcggcttttgatatctggggccgagggacaatggtctccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +944 JY8QFUQ01BR526 No results +945 JY8QFUQ01CTTTC No results +946 JY8QFUQ01DFECA productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 957 94.39 202/214 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [0.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +947 JY8QFUQ01DU75V No results +948 JY8QFUQ01BRZZW No results +949 JY8QFUQ01BVK9J unproductive Homsap IGHV3-48*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAWGSQRR#DYW out-of-frame + ctctggattcaccttcggtaactcaaccatgaactgggtccgccaggctccagggaaggggctggaatggctgtcatatcttagtagtggtggtgatgtcaaatactacgcaggctctctgaagggccgattcaccatctccagagacagtgccaggaactcactgtatctgcaaatgaacagcctgacagacgaggacacggccgtatattactgtgcatgggggtcccaacggcgccgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +950 JY8QFUQ01BBFU0 No results +951 JY8QFUQ01CY5Z7 No results +952 JY8QFUQ01AL68M No results +953 JY8QFUQ01CFFD0 No results +954 JY8QFUQ01B8BOJ No results +955 JY8QFUQ01CCIY9 No results +956 JY8QFUQ01BI1O7 productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CATSPSDFDRRWGYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggatttagctttagaaccttttggatgagctgggtccgccaggctccagggaggggcgtggagtgggtggccaacataaagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +957 JY8QFUQ01B9LUD No results +958 JY8QFUQ01AEXV8 unknown (see comment) Homsap IGHV3-48*01 F (see comment) 482 71.36 142/199 nt 70.85 141/199 nt 8 7 X 8.7.X [1.17.33.X] null - No rearrangement found Low V-REGION identity (71,36% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +959 JY8QFUQ01AXMV3 No results +960 JY8QFUQ01DM849 No results +961 JY8QFUQ01DR9B3 productive Homsap IGHV3-13*01 F 881 90.23 194/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 10 8.7.10 [1.17.38.11] CATISDYRFEFW in-frame - tctctggaatcaccttcagtgactccgacatgcactgggtccgccaagctccaggagaaggtctggagtgggtcgcagctattggaactgctggtgatacatactatgcagactccgtgaagggccgattctccattaccagagagaatgccaagaactccttgtttcttcaaatgaacagcctgagagccgacgacacggctatttattactgtgcgaccattagtgactaccgatttgaattctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +962 JY8QFUQ01AHAOC No results +963 JY8QFUQ01CI89C No results +964 JY8QFUQ01BL574 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 179 59.4 79/133 nt 8 6 X 8.6.X [2.17.11.X] null - No rearrangement found stop codons cctcctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +965 JY8QFUQ01CXG76 No results +966 JY8QFUQ01BUMP8 unknown (see comment) Homsap IGHV1-3*01 F, or Homsap IGHV1-3*02 F (see comment) 265 63.82 97/152 nt 8 8 X 8.8.X [0.17.17.X] null + No rearrangement found Low V-REGION identity (63,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggattcaccttcactgactatgctatgcattgggtgcgccaggcccccggacaagggcttgagtggatgggatggatcaacgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +967 JY8QFUQ01B9HSO No results +968 JY8QFUQ01AXNBU No results +969 JY8QFUQ01CH6IV No results +970 JY8QFUQ01C80PM No results +971 JY8QFUQ01C8ML6 No results +972 JY8QFUQ01DTXID No results +973 JY8QFUQ01ATKPL unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 85 51.49 69/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggatccaccgtcagtacctatagcctgaactgggtccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +974 JY8QFUQ01A49XC unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +975 JY8QFUQ01BXXVF No results +976 JY8QFUQ01DACCQ No results +977 JY8QFUQ01DR4Q4 productive Homsap IGHV3-7*01 F (see comment) 778 84.72 183/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARERSAAGVVFFDFW in-frame - Low V-REGION identity (84,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaggggctggagtgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgcaaatgaacagcctgcgagtcgaggacacggctgtgtatttctgtgcgagagagagatcagcagctggagtcgtcttctttgacttttggggccagggagccccggtcaccgtctccagagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +978 JY8QFUQ01CP4TY No results +979 JY8QFUQ01AKR55 No results +980 JY8QFUQ01B1UTN No results +981 JY8QFUQ01BU42Z No results +982 JY8QFUQ01B5CG9 No results +983 JY8QFUQ01B1H6W No results +984 JY8QFUQ01CCGH3 No results +985 JY8QFUQ01BYK6X unknown (see comment) Homsap IGHV4-61*02 F (see comment) 707 80.73 176/218 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (80,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgccctttgtacacaccgcccgtcgctactaccgattggatggtttagtgaggccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +986 JY8QFUQ01CQI4W No results +987 JY8QFUQ01CC9PC No results +988 JY8QFUQ01ASVKR unknown (see comment) Homsap IGHV1-2*02 F 482 86.61 110/127 nt 8 8 X 8.8.X [0.17.9.X] null + No rearrangement found tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagg +989 JY8QFUQ01AJTX9 No results +990 JY8QFUQ01CW1ZW No results +991 JY8QFUQ01BRKI0 productive Homsap IGHV3-11*01 F 110 61.04 47/77 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 X X 8 X.X.8 [X.X.25.11] CTRRGFMDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tccggattcactttagtgactattggatgagttggatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +992 JY8QFUQ01CVEPJ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F (see comment) 616 75.93 164/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tcgggattcaacttcaagtccaacaccatgaattgggtccgccaggctccagggaaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcggcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccaccaatggatggacgtggtcgtcgcatgcctggtccagggcttct +993 JY8QFUQ01C19QG No results +994 JY8QFUQ01BMH34 No results +995 JY8QFUQ01DJ0DY No results +996 JY8QFUQ01BK19C No results +997 JY8QFUQ01DU3EC unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 199 78.46 51/65 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found tctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccagggcttcttccccc +998 JY8QFUQ01BI2UW No results +999 JY8QFUQ01C40SU No results +1000 JY8QFUQ01AN0PO No results +1001 JY8QFUQ01BTSGB unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1002 JY8QFUQ01BF7X1 No results +1003 JY8QFUQ01A1QF0 No results +1004 JY8QFUQ01DO27W unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 110 60.53 46/76 nt 59.21 45/76 nt 7 X X 7.X.X [1.16.X.X] null + No rearrangement found in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) tctggattcacgttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +1005 JY8QFUQ01DWMO7 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +1006 JY8QFUQ01AOG4M No results +1007 JY8QFUQ01COT7H unknown (see comment) Homsap IGHV1-8*01 F, or Homsap IGHV1-8*02 F (see comment) 242 82.86 58/70 nt 8 X X 8.X.X [0.15.X.X] null + No rearrangement found Low V-REGION identity (82,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatataccttcaccagatatgatatcaattgggtgcgacaggccactggacaagggcttcttccccca +1008 JY8QFUQ01APOXR unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 760 83.8 181/216 nt 83.33 180/216 nt 7 8 X 7.8.X [1.17.38.X] null + No rearrangement found stop codons Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) ctctggatccagtttcagtggtttggcgtgaactaggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1009 JY8QFUQ01DJXIF No results +1010 JY8QFUQ01B62MI No results +1011 JY8QFUQ01A7YQ1 No results +1012 JY8QFUQ01BAM0R productive Homsap IGHV3-21*04 F 958 93.98 203/216 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 163 76.79 43/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSHQVDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcgacttcagtagatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttgatagtaattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcgctgtttctgcaaatgaacagcctgagagccgatgacacggccgtgtattactgtgcgagagccgtgtcgcatcaggtggacgtctggggccaaggggccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1013 JY8QFUQ01B3HHR unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 97 52.67 69/131 nt 8 8 X 8.8.X [1.17.9.X] null - No rearrangement found stop codons tctggattcaccttcagtacctactggatgcactgggtccgccaagttccaaggtcttcccgctgagcctcgacagccaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +1014 JY8QFUQ01C4XVY No results +1015 JY8QFUQ01CU7WL unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 98 52.63 70/133 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1016 JY8QFUQ01BHJ7K No results +1017 JY8QFUQ01AD3VP unknown (see comment) Homsap IGHV1-8*01 F, or Homsap IGHV1-8*02 F (see comment) 246 84.06 58/69 nt 8 X X 8.X.X [0.14.X.X] null - No rearrangement found Low V-REGION identity (84,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatataccttcaccagatatgatatcaattgggtgcgacaggccactggacaagggcttcttcccca +1018 JY8QFUQ01BL6AV No results +1019 JY8QFUQ01CQE2I unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 120 54.55 72/132 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons tctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +1020 JY8QFUQ01C8HC8 productive Homsap IGHV3-21*04 F 990 95.39 207/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame + ctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1021 JY8QFUQ01AIWKD No results +1022 JY8QFUQ01DR3OF unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 467 70.92 139/196 nt 8 7 X 8.7.X [1.17.32.X] null + No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DR3OF ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (70,92% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1023 JY8QFUQ01BFB9X No results +1024 JY8QFUQ01CRXO0 No results +1025 JY8QFUQ01DG75B No results +1026 JY8QFUQ01CJZ05 No results +1027 JY8QFUQ01AY8M2 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 661 78.24 169/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (78,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactatttccccgaaccggtgacggtgtcgtggaactca +1028 JY8QFUQ01CC772 No results +1029 JY8QFUQ01CVZJH productive Homsap IGHV4-61*02 F (see comment) 749 82.35 182/221 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERGASIGEAGGLDSW in-frame + Low V-REGION identity (82,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggccccgtcaacaatggtgatcagtattggagctggatccggcagcccgccgggaaggggctggagtggatcggacgtgtttctgctagtgggacctacagctacaatccctccctcaggagtcggatcaccatctcaatagacatgtctaagaatcacttctccctgaggttgatttctgtgacggccgcagacacggccttatattattgtgcgagagagcgtggtgcgtcgattggcgaagcgggaggccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +1030 JY8QFUQ01C62PI productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F 325 88.1 74/84 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 X X 10 X.X.10 [X.X.28.11] CARLGQLALDYW in-frame + accctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctggggcagcagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaact +1031 JY8QFUQ01AO53D No results +1032 JY8QFUQ01CJY9B No results +1033 JY8QFUQ01CJDOK unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 302 59.63 130/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found stop codons Low V-REGION identity (59,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1034 JY8QFUQ01DMYZ4 No results +1035 JY8QFUQ01DR1XF No results +1036 JY8QFUQ01AFH41 No results +1037 JY8QFUQ01CE24O No results +1038 JY8QFUQ01DU0CJ No results +1039 JY8QFUQ01ABQC1 No results +1040 JY8QFUQ01CBNG6 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 288 65.36 100/153 nt 8 8 X 8.8.X [1.17.16.X] null + No rearrangement found Low V-REGION identity (65,36% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatatgaacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +1041 JY8QFUQ01DKGFO No results +1042 JY8QFUQ01A4GO7 No results +1043 JY8QFUQ01A9IQN No results +1044 JY8QFUQ01BPO33 No results +1045 JY8QFUQ01BM30W No results +1046 JY8QFUQ01DLARJ No results +1047 JY8QFUQ01BBCXQ No results +1048 JY8QFUQ01DRMBU unknown (see comment) Homsap IGHV3-7*03 F (see comment) 460 67.58 148/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (67,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +1049 JY8QFUQ01C35AN No results +1050 JY8QFUQ01DSILW No results +1051 JY8QFUQ01DFH83 No results +1052 JY8QFUQ01ARLLN unproductive Homsap IGHV3-7*01 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 2 8 8 X 8.8.X [1.17.37.11] CGRDERGADLPNDS# out-of-frame + in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 189 in the user submitted sequence), (cause frameshift) tctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagcccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctgggcctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1053 JY8QFUQ01DK988 No results +1054 JY8QFUQ01AZSSK No results +1055 JY8QFUQ01AJ0GL No results +1056 JY8QFUQ01BO45B unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 844 88.73 189/213 nt 87.32 186/213 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 7 8 X 7.8.X [0.16.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) ctggattcgtcttggcgactatgcgatgagctgggtccggcaggctccagggaggggctggagtgggCtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1057 JY8QFUQ01BS4SB No results +1058 JY8QFUQ01DUW53 No results +1059 JY8QFUQ01ALWWB No results +1060 JY8QFUQ01A9QTD productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 910 90.87 199/219 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [2.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame - gggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1061 JY8QFUQ01CCS8Y unknown (see comment) Homsap IGHV5-10-1*03 F 82 63.83 30/47 nt 61.7 29/47 nt X X X X.X.X [15.X.X.X] null + No rearrangement found in FR1-IMGT, from codon 9 of V-REGION: 2 nucleotides (from position 129 in the user submitted sequence), (cause frameshift) tgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggcaaggaccgatgggcccgttcggtggaggtgacgaagccaccagaga +1062 JY8QFUQ01BYQA7 No results +1063 JY8QFUQ01AWDZV No results +1064 JY8QFUQ01C3R1H unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 935 92.56 199/215 nt 92.09 198/215 nt 8 8 X 8.8.X [1.16.38.X] null - No rearrangement found in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccaggaaggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1065 JY8QFUQ01AYQO2 No results +1066 JY8QFUQ01DDCY9 No results +1067 JY8QFUQ01AUX9R unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 279 58.53 127/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (58,53% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaccctaggtacatactggatgcactgggtccgccaggctccagggaaggggccggagtgggtctcagctattactggtcttgatggtagaacattctacgcagactccgtatattattgtgcgaaagagatagcagtgagtggtgagggggcgttggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1068 JY8QFUQ01AGAC7 No results +1069 JY8QFUQ01CST73 productive Homsap IGHV3-9*01 F 792 85.25 185/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-9*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVKDLSGRPKDMHGMDVW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) ctctgggttcagttttagcaattatgccatgcactgggtccgtcaagctccagggaagggcctgcaatgggtctcacgtattaattggaacagtggaaacatagcctatgcggcctctgtgaggggccgattcaccgtctccagagacgacgccgagcactccctgtatttacaaatgaatggtctgacaactgaagacacggccttatactattgtgtgaaagatttgtctggccgaccaaaggacatgcacggcatggacgtctggggccaagggaccacggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1070 JY8QFUQ01B5EL9 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 123 50.95 107/210 nt 8 8 X 8.8.X [1.17.35.X] null - No rearrangement found cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1071 JY8QFUQ01CQUI4 No results +1072 JY8QFUQ01C9ZRN No results +1073 JY8QFUQ01BYZS1 No results +1074 JY8QFUQ01CWZ9S No results +1075 JY8QFUQ01DBEG4 No results +1076 JY8QFUQ01BK3YR No results +1077 JY8QFUQ01A89Y3 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame + ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +1078 JY8QFUQ01CPW4K No results +1079 JY8QFUQ01B0AUU productive (see comment) Homsap IGHV4-61*08 F 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD5-18*01 F 3 10 7 10 10.7.10 [1.16.38.11] CTRGVYTYDSPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) ctctggtgcctccatcagcagtagtggtcactactggagttggatccggcagcccccagggaagggactggaattcattggaaaatctattccaatgggaacgccaactacaacccctccttcaagagtcgagtcaccatttcagtggacacgtccgagaaccagttctccctgagcctgaggtctgtgaccgctgcggacacggccctttattactgtacgaggggggtatacacttatgacagcccgtggggccaggggattcaggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttctt +1080 JY8QFUQ01DTQET No results +1081 JY8QFUQ01CAWWF No results +1082 JY8QFUQ01DSK89 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 942 92.27 203/220 nt 90.45 199/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'GA' (2 nucleotides at position 91 to 92 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 77 of V-REGION: 'A' (1 nucleotides at position 142 to 142 in the user submitted sequence), (cause frameshift); agcctctggattGcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggGtgtgggtgtcacgtagtaatGAccgggggggactgacacagcctacgcggactccgtgaagggccgattcaAccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1083 JY8QFUQ01AV6IN No results +1084 JY8QFUQ01CIHK9 unknown (see comment) Homsap IGHV7-81*01 ORF 98 76.47 26/34 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found tctggattcagcctcgccacttatagtatgagtt +1085 JY8QFUQ01DC6KD productive Homsap IGHV3-7*01 F 1027 96.8 212/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-1*01 F 1 8 8 10 8.8.10 [2.17.38.11] CTKDTFGREDYW in-frame - gcctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1086 JY8QFUQ01AWGAC unknown (see comment) Homsap IGHV3-23*05 F 88 53.85 56/104 nt 52.88 55/104 nt 7 8 X 7.8.X [1.17.X.X] null + No rearrangement found stop codons in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift) ctctggattcgtcttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccac +1087 JY8QFUQ01AB5PD unknown (see comment) Homsap IGHV3-48*03 F, or Homsap IGHV3-48*04 F (see comment) 345 66.1 117/177 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (66,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcaccttcactagaagtcccatgaattgggtccgccaggctccggggaaggggctggaatgggttgcatacattagtagtgatggtagtaccctatactacgcagactctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1088 JY8QFUQ01B631L No results +1089 JY8QFUQ01CGXM9 unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1090 JY8QFUQ01AW87B No results +1091 JY8QFUQ01BA3U4 No results +1092 JY8QFUQ01BMGQY productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARPLRATYGDYVNW in-frame + ctctggattcaccttcgataactatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcaaaggatggaagtattgaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacaatttatctgcaaatgaacattgtgagggttgaggacacggctatgtattactgtgcgagaccccttcgggcaacttacggtgactacgtgaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1093 JY8QFUQ01C04FC No results +1094 JY8QFUQ01CTB7Y No results +1095 JY8QFUQ01CYGJK unknown (see comment) Homsap IGHV4-61*06 ORF (see comment) 328 61.11 132/216 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (61,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +1096 JY8QFUQ01CKMH6 unknown (see comment) Homsap IGHV3-13*02 F 87 51.94 67/129 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found ctctggattcagcttaagttcttatggcatgaactgggtccgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaact +1097 JY8QFUQ01B01ZN No results +1098 JY8QFUQ01A3GGK No results +1099 JY8QFUQ01BBM9Y No results +1100 JY8QFUQ01CQUMX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 506 87.79 115/131 nt 87.02 114/131 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 1 15 8.1.15 [1.17.16.11] CVRVKRFGSGNVLFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 86 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) ctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccaacagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +1101 JY8QFUQ01DJV40 No results +1102 JY8QFUQ01C8PC1 productive Homsap IGHV3-7*01 F 1030 97.69 211/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + tctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +1103 JY8QFUQ01B70IY No results +1104 JY8QFUQ01DC1VC unproductive Homsap IGHV3-48*01 F 1080 99.54 216/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CASIFGSGSPG##YYYGMDVW out-of-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttgggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggcctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc +1105 JY8QFUQ01DO9NG No results +1106 JY8QFUQ01C24ZT productive Homsap IGHV3-9*01 F 1026 97.24 211/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-20*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKDMGYTWKYIDHW in-frame + ctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattacttggaacagtggtaggataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattattgtgcaaaagatatggggtatacctggaagtacattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1107 JY8QFUQ01AQSH7 No results +1108 JY8QFUQ01DWGXO productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 730 81.28 178/219 nt 79.91 175/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 10 8.8.10 [2.17.37.11] CAKDDSAGLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 90 of V-REGION: 'G' (1 nucleotides at position 178 to 178 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 100 of V-REGION: 1 nucleotides (from position 207 in the user submitted sequence), (cause frameshift) agcctccggattcatcttcagtgccgcttggatggagtgggtccgccaagttccagggcacgggctcgtgtgggtcgcgcgtatcgagagtagtggcagcggcaCacgtttacgcggactacgtgaagggccgattcaccgtctccagagacaacgccatgaacatagtgtatcttcGaaatgaattctctgactgccgaggacacggtgtgtattactgcgcaaaggatgattcggccggccttgaccattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1109 JY8QFUQ01ASB5I No results +1110 JY8QFUQ01DCWY7 productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1111 JY8QFUQ01BVEDT productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc +1112 JY8QFUQ01BW39X unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +1113 JY8QFUQ01A2Z61 No results +1114 JY8QFUQ01CMY95 No results +1115 JY8QFUQ01CPVHO No results +1116 JY8QFUQ01DRPK1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1117 JY8QFUQ01DDZDR unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt 91.36 201/220 nt 10 7 X 10.7.X [1.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagcagtgataatttctactggggctggatccgccagccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgaaccggtgacggtgtcgtggaactcag +1118 JY8QFUQ01CWDLL No results +1119 JY8QFUQ01DKIIE No results +1120 JY8QFUQ01DUAQJ No results +1121 JY8QFUQ01BZSHA No results +1122 JY8QFUQ01BVUN8 No results +1123 JY8QFUQ01BQK5C productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +1124 JY8QFUQ01DEC6U No results +1125 JY8QFUQ01DJDJH No results +1126 JY8QFUQ01A5Z0G productive Homsap IGHV4-30-4*07 F, or Homsap IGHV4-31*01 F or Homsap IGHV4-31*02 F or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F or Homsap IGHV4-31*06 F or Homsap IGHV4-31*07 F or Homsap IGHV4-31*08 F or Homsap IGHV4-34*09 F or Homsap IGHV4-59*06 F (see comment) 248 75.0 69/92 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 X X 18 X.X.18 [X.X.30.11] CARSAYCGADCYSADYLQHW in-frame - Low V-REGION identity (75,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggctccgtcagcaacacgtctaagaaccaattctccctgaagttgacctctatgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +1127 JY8QFUQ01AN2IT No results +1128 JY8QFUQ01A7NI5 No results +1129 JY8QFUQ01C0IMB No results +1130 JY8QFUQ01DR8PG productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 925 90.99 202/222 nt 90.54 201/222 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [1.17.38.11] CTTAPSETYATEYFAMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 121 to 121 in the user submitted sequence), (cause frameshift); tctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgccCcccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactanttccccgaaccggtgacggtgtcgtggaactc +1131 JY8QFUQ01DC95U No results +1132 JY8QFUQ01DQ0U7 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +1133 JY8QFUQ01DRSJM No results +1134 JY8QFUQ01CGGKR No results +1135 JY8QFUQ01DIWKI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1136 JY8QFUQ01A604Q No results +1137 JY8QFUQ01CBA2P productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctggctgcctggtcaaggactacttccccgaaccgtgacggtgtcgtggaactcag +1138 JY8QFUQ01DQ2FL No results +1139 JY8QFUQ01BT3ET unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 104 75.68 28/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcagtatttataattattggatgaattgg +1140 JY8QFUQ01CUB57 No results +1141 JY8QFUQ01B2KH9 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 967 96.62 200/207 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 6 8 16 6.8.16 [X.17.38.11] CARQIDYGDFSRHGLDVW in-frame + aactttaccggctactggatcggctgggtgcgccagcggcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgataccagatacagcccatccttccaaggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccgtgtattactgtgcgagacaaatagactacggtgacttctctaggcacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1142 JY8QFUQ01BZJNZ unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1143 JY8QFUQ01AZJQY No results +1144 JY8QFUQ01BY4UF No results +1145 JY8QFUQ01CYT8I productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDFW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtaatgtctcctagcatcccgaccagcccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +1146 JY8QFUQ01DWMEP No results +1147 JY8QFUQ01C9FUL unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*03 F or Homsap IGHV4-34*04 F or Homsap IGHV4-34*06 F or Homsap IGHV4-34*07 F or Homsap IGHV4-34*09 F or Homsap IGHV4-34*10 F or Homsap IGHV4-34*12 F or Homsap IGHV4-59*10 F 103 58.75 47/80 nt 8 X X 8.X.X [2.16.X.X] null + No rearrangement found gtctatggtgggtccttcagtacttactactggacatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +1148 JY8QFUQ01CW2ZQ unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt +1149 JY8QFUQ01DJ6VW No results +1150 JY8QFUQ01BIZZ1 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +1151 JY8QFUQ01DLX1J No results +1152 JY8QFUQ01A00IV No results +1153 JY8QFUQ01C8PKK No results +1154 JY8QFUQ01DA5XZ No results +1155 JY8QFUQ01DK0VJ No results +1156 JY8QFUQ01CGZHZ No results +1157 JY8QFUQ01C2JYS No results +1158 JY8QFUQ01DJJED No results +1159 JY8QFUQ01C6R2Q unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 87 51.94 67/129 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons tctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +1160 JY8QFUQ01DRI4N No results +1161 JY8QFUQ01A8XXA productive Homsap IGHV3-11*01 F 938 93.87 199/212 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 7 8 13 7.8.13 [X.17.38.11] CARDLQLGDDSGFSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gattcaccctcagtgactactacatgacttggatccgccaggctccagggaaggggctggagtgggtttcgtacattagtagtctcactagttccatatattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactatatctgcaaatggacagcctgagagccgaggacacggccgtgtattactgtgcgagagatcttcagctgggggatgatagtgggttttcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +1162 JY8QFUQ01C72YN No results +1163 JY8QFUQ01C05LQ No results +1164 JY8QFUQ01C89I5 No results +1165 JY8QFUQ01CO70A No results +1166 JY8QFUQ01A9Y62 No results +1167 JY8QFUQ01BMSRM unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null - stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); gcctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtactaataCgtggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattattgtgcaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1168 JY8QFUQ01BCUQT No results +1169 JY8QFUQ01CP7NH productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F (see comment) 688 80.09 173/216 nt 79.17 171/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.16.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaagggccggagtgggtggccaacatatccccagacggaatacgaaatacttttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1170 JY8QFUQ01AP0N2 unproductive Homsap IGHV4-61*02 F 803 85.07 188/221 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-16*01 F 1 10 7 X 10.7.X [1.17.38.11] CAREHSSSIGGERELDS## out-of-frame + tgtctggtggccccatcagcagtagtggcttcgcctggacctggatccggcagaccgccgggaagggactggagtggatcggacgtgtttatggtagtgggaataccaattacagtccttccctccagagtcgagtcaccatatcagtagagacgtccaagaatcagttctccctgaggttgacttctgtgaccgccgcagacacgggcctatattactgtgcgagagaacatagtagttcgattggcggagagagagaacttgactcctggggccagggaacccgaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1171 JY8QFUQ01A4CK6 No results +1172 JY8QFUQ01CPBZS No results +1173 JY8QFUQ01DRYJ8 No results +1174 JY8QFUQ01BF63V No results +1175 JY8QFUQ01CPQ1I No results +1176 JY8QFUQ01A6S5X No results +1177 JY8QFUQ01BFEB0 No results +1178 JY8QFUQ01A5T2M No results +1179 JY8QFUQ01BHKZ9 No results +1180 JY8QFUQ01CQJTH No results +1181 JY8QFUQ01DGCF0 No results +1182 JY8QFUQ01BLI8D No results +1183 JY8QFUQ01AQO2N unknown (see comment) Homsap IGHV1-8*01 F, or Homsap IGHV1-8*02 F (see comment) 246 84.06 58/69 nt 8 X X 8.X.X [0.14.X.X] null + No rearrangement found Low V-REGION identity (84,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatataccttcaccagatatgatatcaattgggtgcgacaggccactggacaagggcttcttcccca +1184 JY8QFUQ01AKIMH No results +1185 JY8QFUQ01BK3VC No results +1186 JY8QFUQ01B18O2 No results +1187 JY8QFUQ01CM65D unknown (see comment) Homsap IGHV3-30*09 F, or Homsap IGHV3-33*01 F or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F (see comment) 363 64.22 131/204 nt 63.73 130/204 nt 8 7 X 8.7.X [1.17.34.X] null + No rearrangement found Low V-REGION identity (64,22% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 99 in the user submitted sequence), (cause frameshift) tctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1188 JY8QFUQ01CDTPI No results +1189 JY8QFUQ01DHVD2 No results +1190 JY8QFUQ01DIQYK productive (see comment) Homsap IGHV1-8*01 F 826 87.79 187/213 nt 86.85 185/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 12 8.8.12 [0.17.37.11] CARGRGYGSYADHW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 71 of V-REGION: 1 nucleotides (from position 118 in the user submitted sequence), (cause frameshift) tggatacagcttcagcaattatgatatcaactgggtgcggcaggccactggacaagggcttcagtggatggggtggatgaaGcccccacagtgccaatatcgtctacgcgcagaaattcagggcagagtcaccatgaccagtgacgcctccataaccacagcctacatggaactgagcaacctgaaatctgacgacacggccgtgtattattgtgcgaggggccgagggtacggaagttacgctgaccactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +1191 JY8QFUQ01DC8AC No results +1192 JY8QFUQ01CT6QT No results +1193 JY8QFUQ01DSZ8X unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 730 81.74 179/219 nt 80.82 177/219 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD3-3*02 F 1 8 8 X 8.8.X [2.17.38.11] CARIWDSWSG#FDVW out-of-frame - Low V-REGION identity (81,74% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 44 of V-REGION: 'CAA' (3 nucleotides at position 47 to 49 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); gcctctggattcccctttagtgtgtactggatgtactgggtccgccCAAaagtcccgggaagggggccggtatgggtcgcacgtatcCagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagctttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1194 JY8QFUQ01AX7M1 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 166 58.21 78/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found tctggattcaccttcagcaaccataacatgaactgggtccgccaggctcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1195 JY8QFUQ01C5CLM No results +1196 JY8QFUQ01DFYDB No results +1197 JY8QFUQ01BOEUU No results +1198 JY8QFUQ01BJ9BI unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*02 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*04 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*08 F or Homsap IGHV3-30*10 F or Homsap IGHV3-30*11 F or Homsap IGHV3-30*16 F or Homsap IGHV3-30*17 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-3*01 F 402 92.55 87/94 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 1 X X X X.X.X [X.X.31.11] CAKDELPWDTIEYYFDY# out-of-frame + ctctggattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatgagctgccttgggacacaattgaatattattttgactattgggccagggaagcctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1199 JY8QFUQ01DSOKK productive Homsap IGHV3-11*01 F 942 92.27 203/220 nt Homsap IGHJ6*01 F 252 88.89 56/63 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [2.17.38.11] CVRYWGSYYYYNGLDVW in-frame - gcctctgggattcaccttcactgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcacacattagtagtggtggtagaaccattgcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtttctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgagatattggggcagctactattactataacggtctggacgtctgggggcaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +1200 JY8QFUQ01DB8H0 No results +1201 JY8QFUQ01BBHB9 No results +1202 JY8QFUQ01A2SDF unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 315 60.37 131/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (60,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcacctttagcagctatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaagtatcagttttagtggtgagagaacatattatgcagactccgtatattactgtgcgaaagatctggtggtgactagtattggcccccagggaatccatggccactgggccagggaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccctccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +1203 JY8QFUQ01CUBOD No results +1204 JY8QFUQ01BP4KM unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 449 67.44 145/215 nt 66.05 142/215 nt 8 8 X 8.8.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (67,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 67 of V-REGION: 'ATGGTGCATGCTATGT' (16 nucleotides at position 109 to 124 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'TCTGGGGC' (8 nucleotides at position 133 to 140 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 72 of V-REGION: 2 nucleotides (from position 124 in the user submitted sequence), (cause frameshift) ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactaATGGTGCATGCTATGTcgccgactTCTGGGGCcagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1205 JY8QFUQ01AVYPI No results +1206 JY8QFUQ01B8SVY No results +1207 JY8QFUQ01AU3G2 No results +1208 JY8QFUQ01BHUZH No results +1209 JY8QFUQ01BV4GW productive Homsap IGHV4-39*02 F 839 86.88 192/221 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggacgtggtcatcgcctgcctggtccagggcttcttccccg +1210 JY8QFUQ01AD9B1 No results +1211 JY8QFUQ01ARPTV No results +1212 JY8QFUQ01DH04C unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.16.38.11] CARKRVPGGTFYGTT# out-of-frame + in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaagggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatgggactactgggccagggaaccctggtcaccgtctcctcagccgtccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +1213 JY8QFUQ01BNGHE No results +1214 JY8QFUQ01ALASO No results +1215 JY8QFUQ01C8ZD0 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 563 72.94 159/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (72,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctagattcatctttagtagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactatcagtggtagtggtgataacacatactacgcagactccgtgaagggccggttcaccatctccagagacaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +1216 JY8QFUQ01BMX3R No results +1217 JY8QFUQ01CF8LE No results +1218 JY8QFUQ01BRBF4 No results +1219 JY8QFUQ01DFQZQ No results +1220 JY8QFUQ01DDPAR No results +1221 JY8QFUQ01AR8WH No results +1222 JY8QFUQ01BB4FI unknown (see comment) Homsap IGHV7-81*01 ORF 156 60.95 64/105 nt 8 8 X 8.8.X [0.17.1.X] null - No rearrangement found cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggccagatgggaacgtggtcatcgcctgcctggtccaggcttcttcccca +1223 JY8QFUQ01AIT8M unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 467 68.37 147/215 nt 67.91 146/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (68,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) tctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1224 JY8QFUQ01C2NS9 No results +1225 JY8QFUQ01AZ5C6 No results +1226 JY8QFUQ01CTWUE unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 756 82.95 180/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1227 JY8QFUQ01AQY8E No results +1228 JY8QFUQ01C9LXB No results +1229 JY8QFUQ01DRL69 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +1230 JY8QFUQ01CARXR No results +1231 JY8QFUQ01CKVI0 No results +1232 JY8QFUQ01A4RVS unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt 92.79 206/222 nt 8 7 X 8.7.X [4.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaagggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +1233 JY8QFUQ01C41HM unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*03 F or Homsap IGHV3-48*04 F (see comment) 322 64.77 114/176 nt 64.2 113/176 nt 8 8 X 8.8.X [1.16.24.X] null + No rearrangement found Low V-REGION identity (64,77% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcactagaagtcccatgaattgggtccgccaggctccggggaagggctggaatgggttgcatacattagtagtgatggtagtaccctatactacgcagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +1234 JY8QFUQ01B8HKV unknown (see comment) Homsap IGHV4-61*02 F (see comment) 671 78.44 171/218 nt 10 7 X 10.7.X [1.17.37.X] null - No rearrangement found Low V-REGION identity (78,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgactccatcaccagtggtaattattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggatcaccaactacaatccctccctcaagagtcgagtcaccatactattagacacgtccagcaaccggttctccctgaagctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1235 JY8QFUQ01A1SBX No results +1236 JY8QFUQ01DOHBI No results +1237 JY8QFUQ01DMOR8 No results +1238 JY8QFUQ01BGVNK No results +1239 JY8QFUQ01A6GVM productive (see comment) Homsap IGHV1-2*02 F 790 85.51 183/214 nt 84.11 180/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDWGGTYAPLDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'C' (1 nucleotides at position 207 to 207 in the user submitted sequence), (cause frameshift); tggatacattttcaccggGctactatttacactgggngcgccaggccgctggacaagggcttgagtggatgggatAcaatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaaccttgaccagtgacacgtccatcagtacagcctacatggaaatgagcgggctgacgtctgaggacacggccatCattttactgtgcgagagattggggtggcacgtacgctccgcttgacaattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1240 JY8QFUQ01CIBS1 No results +1241 JY8QFUQ01CH2HJ No results +1242 JY8QFUQ01C5WR5 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 197 95.35 41/43 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found tctggattcaccttcagtagctactggatgcactgggtcccca +1243 JY8QFUQ01DAQWO No results +1244 JY8QFUQ01DDXDI No results +1245 JY8QFUQ01BHLRQ No results +1246 JY8QFUQ01DQ3GA unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +1247 JY8QFUQ01BNQZ4 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 474 82.61 114/138 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (82,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc +1248 JY8QFUQ01C2265 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 89 58.57 41/70 nt 8 X X 8.X.X [1.14.X.X] null + No rearrangement found ctctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttcccc +1249 JY8QFUQ01CSEV0 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 795 85.98 184/214 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD2-21*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSVGRYGMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tcgggggttcagcgtcaataataacttcatgacttggttccgccaggttccagggaaggggctggagtgggtctcagttatctatacaaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccgagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtactactgtgcgagagaatttcgggcgccttctgtgggcagatatggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1250 JY8QFUQ01A3SXJ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1251 JY8QFUQ01ASIZV No results +1252 JY8QFUQ01DGWCG unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 774 83.87 182/217 nt Homsap IGHJ2*01 F (see comment) 32 63.16 12/19 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttcccgaaccggtgacggtgtcgtggaactcag +1253 JY8QFUQ01CS0CM unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 503 93.04 107/115 nt 8 8 X 8.8.X [1.17.4.X] null + No rearrangement found ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagac +1254 JY8QFUQ01CYKYB No results +1255 JY8QFUQ01AF6RU unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 278 64.9 98/151 nt 8 8 X 8.8.X [1.17.16.X] null + No rearrangement found Low V-REGION identity (64,90% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatatgaacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +1256 JY8QFUQ01B5FVD No results +1257 JY8QFUQ01A1IOS No results +1258 JY8QFUQ01DPWH7 No results +1259 JY8QFUQ01BDH34 productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1260 JY8QFUQ01BHLIP No results +1261 JY8QFUQ01DEJND unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*04 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*03 F or Homsap IGHV3-66*04 F (see comment) 259 72.12 75/104 nt 8 7 X 8.7.X [1.17.1.X] null + No rearrangement found Low V-REGION identity (72,12% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggcttcaccgtcaataacaactacatgggctgggtccgccaggctccagggaaggggctggagtgggtcatcgcctgcctggtccagggcttcttcctcca +1262 JY8QFUQ01A7P9Y No results +1263 JY8QFUQ01CCKWW No results +1264 JY8QFUQ01BJYX3 No results +1265 JY8QFUQ01CROHU No results +1266 JY8QFUQ01AVYK5 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 169 76.27 45/59 nt 8 X X 8.X.X [1.10.X.X] null + No rearrangement found ctctggattcaacttcagaacctattggatgggctgggtccgccaggcttcttccccca +1267 JY8QFUQ01AFCOL No results +1268 JY8QFUQ01AZOHA No results +1269 JY8QFUQ01DQPKO No results +1270 JY8QFUQ01A0KS4 No results +1271 JY8QFUQ01BPLHT No results +1272 JY8QFUQ01AJKSG No results +1273 JY8QFUQ01CR0BH No results +1274 JY8QFUQ01B8REL No results +1275 JY8QFUQ01DVIPJ No results +1276 JY8QFUQ01AP99O No results +1277 JY8QFUQ01CZYVE productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 879 89.09 196/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + ctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1278 JY8QFUQ01BJG1Z productive Homsap IGHV4-61*02 F 960 93.18 205/220 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + ctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +1279 JY8QFUQ01CYA4K No results +1280 JY8QFUQ01BLI2G No results +1281 JY8QFUQ01DV6CZ No results +1282 JY8QFUQ01C8713 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1283 JY8QFUQ01ANMZ3 No results +1284 JY8QFUQ01DOD03 No results +1285 JY8QFUQ01CGBI4 No results +1286 JY8QFUQ01CJK9L No results +1287 JY8QFUQ01AA6QP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + tctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +1288 JY8QFUQ01C2R2R No results +1289 JY8QFUQ01BPPKV productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 854 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 7 8 10 7.8.10 [1.17.38.11] CTKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) ctctggattcacttcagtagatactggatgcactgggtccgccaggctccagggaatggggctggantggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1290 JY8QFUQ01BW5D4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 813 86.92 186/214 nt 85.98 184/214 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.16.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 32 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) tctggattcacatttagaagctattccatgaattggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +1291 JY8QFUQ01BSEMY unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 764 84.19 181/215 nt 83.72 180/215 nt 7 8 X 7.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) tctggatccagtttcagtggtttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgctttattcggctacgctaggtacgacgctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1292 JY8QFUQ01BSEQW No results +1293 JY8QFUQ01CGVDD unknown (see comment) Homsap IGHV4-61*02 F (see comment) 262 83.78 62/74 nt 10 X X 10.X.X [1.13.X.X] null + No rearrangement found Low V-REGION identity (83,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgcctggatccggcagccc +1294 JY8QFUQ01DKZY8 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +1295 JY8QFUQ01ABF0G No results +1296 JY8QFUQ01DFO71 No results +1297 JY8QFUQ01AOLHE productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 732 82.71 177/214 nt 82.24 176/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.16.38.11] CARDWGGSFDRYYFDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 72 in the user submitted sequence), (cause frameshift) tccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1298 JY8QFUQ01CCCWF No results +1299 JY8QFUQ01CV38P No results +1300 JY8QFUQ01DHU9H No results +1301 JY8QFUQ01A8R7D No results +1302 JY8QFUQ01AFEL3 No results +1303 JY8QFUQ01C6OUF No results +1304 JY8QFUQ01BUCPI No results +1305 JY8QFUQ01DGGI5 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +1306 JY8QFUQ01C9LSL No results +1307 JY8QFUQ01CLT61 No results +1308 JY8QFUQ01B7VCF productive (see comment) Homsap IGHV4-61*02 F (see comment) 672 78.64 173/220 nt 78.18 172/220 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.37.11] CARDRRRSIAGARHFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (78,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) tctctggtggccccaccatcgatgatggtgatttgtggacctggatccggcagcccgccggcaagggactggaatggatcggttatgtctatgatgggcggggcaccaactccaaccctccctccggagtcgcgttaccctgtcacaagacacctcaaacaatcagttcttcttgaggttgaagtctgtgaccgcctcagacacggccgtctattactgtgcgcgagaccgccgtaggtcgattgccggagcgagacactttgactcctggggccagggaatcctggccaccgtcgccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1309 JY8QFUQ01CX09A No results +1310 JY8QFUQ01DS2IL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1311 JY8QFUQ01BJS3X No results +1312 JY8QFUQ01B9JVU No results +1313 JY8QFUQ01CTJN4 No results +1314 JY8QFUQ01A15NY No results +1315 JY8QFUQ01AKU5E No results +1316 JY8QFUQ01DDRDF No results +1317 JY8QFUQ01CIM27 unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 845 88.37 190/215 nt 87.44 188/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 2 8 8 X 8.8.X [1.16.38.11] CARPPSGNLR*LR##W out-of-frame + stop codons in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) tctggattcagtttcagtgactactacatgagttggatccgccaggctccagggaggggctggagtgggAtggcagttatatcaaaggatggaagtattgaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacaatttatctgcaaatgaacattgtgagggttgaggacacggctatgtattactgtgcgagacccccttcgggcaacttacggtgactacgtgaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1318 JY8QFUQ01CN504 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +1319 JY8QFUQ01C4DMZ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 7 11 8.7.11 [1.17.38.11] CARVGTFNWFGPW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatcccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +1320 JY8QFUQ01CUZGQ No results +1321 JY8QFUQ01B2PD2 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 186 97.44 38/39 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found cctctggattcatcttcagtagctactggatgcactggg +1322 JY8QFUQ01AK2U7 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +1323 JY8QFUQ01CBZLK No results +1324 JY8QFUQ01DDBZE No results +1325 JY8QFUQ01C1F2F No results +1326 JY8QFUQ01ANVQ1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccgggcttcttccccca +1327 JY8QFUQ01BUDKT productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 822 89.27 183/205 nt 87.8 180/205 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 49 of V-REGION: 'GAC' (3 nucleotides at position 52 to 54 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 9 nucleotides (from position 14 in the user submitted sequence), (do not cause frameshift) ctctggtgactcccacttctggagctggatccggcagcccccgggcaaaggGACcgtggagtggattggttatgtctataacagtgGggaccaccaactacaacccctccctcaggagtcgagtcaccatgtctatagacacgtccaagaagcagatctctctgaggttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactcctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +1328 JY8QFUQ01AOUHJ No results +1329 JY8QFUQ01A781M No results +1330 JY8QFUQ01AI9X8 No results +1331 JY8QFUQ01CCSB5 No results +1332 JY8QFUQ01BM6J4 No results +1333 JY8QFUQ01AI0EO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - gcctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1334 JY8QFUQ01CF5LR No results +1335 JY8QFUQ01DI64T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + tctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1336 JY8QFUQ01AMGQO No results +1337 JY8QFUQ01BL0WC productive (see comment) Homsap IGHV3-7*02 F, or Homsap IGHV3-7*03 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 7 8 8 7.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) tccggattcattttggtgactattggatgagctgggtccgccaggttccagggaaaggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttctt +1338 JY8QFUQ01CI2RN No results +1339 JY8QFUQ01DBKKS No results +1340 JY8QFUQ01CGQRQ No results +1341 JY8QFUQ01AJJSD unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +1342 JY8QFUQ01DJRW9 No results +1343 JY8QFUQ01BT69S No results +1344 JY8QFUQ01BH3O9 No results +1345 JY8QFUQ01DKVGF No results +1346 JY8QFUQ01DT06M No results +1347 JY8QFUQ01CTS9U No results +1348 JY8QFUQ01BO326 No results +1349 JY8QFUQ01AZLQP No results +1350 JY8QFUQ01BQ2TE unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 116 96.0 24/25 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found tccggggacagtgtctctaccaaca +1351 JY8QFUQ01AEAZN No results +1352 JY8QFUQ01AJ6QO No results +1353 JY8QFUQ01C9GES No results +1354 JY8QFUQ01DVP6C No results +1355 JY8QFUQ01BK8J7 No results +1356 JY8QFUQ01B6GEZ No results +1357 JY8QFUQ01CX2G5 No results +1358 JY8QFUQ01CT4TV No results +1359 JY8QFUQ01AHIYN No results +1360 JY8QFUQ01DSN5H unknown (see comment) Homsap IGHV4-31*06 F, or Homsap IGHV4-61*01 F or Homsap IGHV4-61*03 F or Homsap IGHV4-61*04 F 140 58.72 64/109 nt 10 7 X 10.7.X [2.17.X.X] null - No rearrangement found gtctctggtgcctccgtcagcagtggtagtttctactggacctggattcgtcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +1361 JY8QFUQ01DR0EH No results +1362 JY8QFUQ01BPUDU No results +1363 JY8QFUQ01DA687 productive (see comment) Homsap IGHV3-11*01 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1364 JY8QFUQ01CUQXS No results +1365 JY8QFUQ01DE6AA productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 937 92.24 202/219 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [2.17.38.11] CARGMATAESW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gcctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1366 JY8QFUQ01CZVUB unknown (see comment) Homsap IGHV3-7*01 F 1040 97.71 213/218 nt 96.79 211/218 nt 8 8 X 8.8.X [2.16.38.X] null - No rearrangement found in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 44 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) agcctctggattcaggtttagcatctattggatgagctgggtcgccaggctccagggaaggggctggagtggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +1367 JY8QFUQ01CVJ6V No results +1368 JY8QFUQ01A7KDU unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 103 52.99 71/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1369 JY8QFUQ01B4FNK unknown (see comment) Homsap IGHV3-72*01 F 110 53.85 70/130 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +1370 JY8QFUQ01DGFLY productive Homsap IGHV1-69*08 F 930 92.99 199/214 nt Homsap IGHJ4*03 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARDSNGYSSGYIDCW in-frame + tggaggctccttcggcagctacactatcacctgggtgcgacaggcccctggacaagggcttgagtggatgggaaggatcacccctatccttggttcaacaagctactcacagaagttccagggcagagtcacgattaccgcggacacattcacgggcacagcctacatggagctgagcagcctgacatctgaagacacggccgtatattactgtgcgcgagactcgaatggatacagttctggttatattgactgctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +1371 JY8QFUQ01CC6Q7 No results +1372 JY8QFUQ01CC0O7 No results +1373 JY8QFUQ01DBP2G unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 434 77.03 114/148 nt 8 8 X 8.8.X [1.17.14.X] null - No rearrangement found Low V-REGION identity (77,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctacgtggtcgtcgcatgcctggtccagggcttcttccccca +1374 JY8QFUQ01A4FRD No results +1375 JY8QFUQ01AZQDI No results +1376 JY8QFUQ01CY2SC No results +1377 JY8QFUQ01A7W88 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 97 52.67 69/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +1378 JY8QFUQ01DP5C8 No results +1379 JY8QFUQ01A68NC No results +1380 JY8QFUQ01C968T unknown (see comment) Homsap IGHV3-74*03 F 113 54.33 69/127 nt 8 8 X 8.8.X [1.17.7.X] null - No rearrangement found cctctggattcaccttcagtagctactggatgcactgggtccgccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1381 JY8QFUQ01A2IM0 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 151 57.25 75/131 nt 8 6 X 8.6.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccagcatggagacgtggtcgtcgcatgcctggtccagggcttcttccccc +1382 JY8QFUQ01BHB4N No results +1383 JY8QFUQ01BNESV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARRTITAAGRGDDYW in-frame + ctctgaattcacctttagcagttttgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagcattggtactagtgttgttaacacatggtacgcagactcagtgaagggccggttcgccatttccagagacaattccaagagcacgctgtatttgcaaatgaatagcctgagagtcgaggacacggccgtatattactgtgcgaggaggacaataacagcagctggccgtggggatgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1384 JY8QFUQ01AVAWG unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 751 82.87 179/216 nt 82.41 178/216 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found Low V-REGION identity (82,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaagggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1385 JY8QFUQ01DUNEQ No results +1386 JY8QFUQ01CDFK1 productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcc +1387 JY8QFUQ01AMW7J No results +1388 JY8QFUQ01DEGDT No results +1389 JY8QFUQ01B3HPK No results +1390 JY8QFUQ01AFBP7 No results +1391 JY8QFUQ01BSOH5 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 78 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggcgtggagtgggtctctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +1392 JY8QFUQ01DULGP productive Homsap IGHV3-48*03 F, or Homsap IGHV3-48*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P (see comment) 357 75.38 98/130 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 X 5 13 X.5.13 [X.X.38.11] CATSPSDFDRRWGYW in-frame + Low V-REGION identity (75,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggatttagctttagaaccttttggatgagctggggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +1393 JY8QFUQ01CT5ZJ unknown (see comment) Homsap IGHV1-NL1*01 P 90 56.79 46/81 nt 2 X X 2.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagagac +1394 JY8QFUQ01DWD6E productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 878 89.45 195/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + cctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +1395 JY8QFUQ01AHAAA unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt 99.54 216/217 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDFFIGGYYGMDV# out-of-frame + in FR3-IMGT at codon 94 of V-REGION: 'CG' (2 nucleotides at position 186 to 187 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagccCGtgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctgggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgtgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +1396 JY8QFUQ01BSWTU unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*05 F or Homsap IGHV3-30*13 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F (see comment) 286 72.57 82/113 nt 8 8 X 8.8.X [2.17.2.X] null + No rearrangement found Low V-REGION identity (72,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgctctggattcaacttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagtcatcgcctgcctggtccagggcttcttccccca +1397 JY8QFUQ01DXHWW unknown (see comment) Homsap IGHV3-16*01 ORF, or Homsap IGHV3-16*02 ORF or Homsap IGHV3-19*01 P or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-35*01 ORF or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 139 88.57 31/35 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found ctctggattcaccttcagcaaccataacatgaact +1398 JY8QFUQ01CQG7G productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 777 85.05 182/214 nt 84.58 181/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD2-21*01 F 2 8 8 13 8.8.13 [0.17.37.11] CARRSGRDGGWFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 75 of V-REGION: 1 nucleotides (from position 126 in the user submitted sequence), (cause frameshift) ctggattcatctttgccgactatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtcgcagatattaatggaagaggtgctgccgcacactacgcagactccgtgacgggcgcttcaccctctacaaagacggttccaagaatacgatgtatctgcaaatgaggaccctgagagacgacgacacggccaaatattactgtgcgagacgaagtgggcgtgatgggggctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1399 JY8QFUQ01CHINB No results +1400 JY8QFUQ01CWJ1D No results +1401 JY8QFUQ01BWRJM No results +1402 JY8QFUQ01APTE0 No results +1403 JY8QFUQ01DH93K No results +1404 JY8QFUQ01A74DO No results +1405 JY8QFUQ01A3LNS No results +1406 JY8QFUQ01AX86C No results +1407 JY8QFUQ01C49LY No results +1408 JY8QFUQ01BP7AC No results +1409 JY8QFUQ01BSO0Y unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +1410 JY8QFUQ01BS5BQ No results +1411 JY8QFUQ01CEMVD No results +1412 JY8QFUQ01DG5H6 No results +1413 JY8QFUQ01DFDK1 No results +1414 JY8QFUQ01CAA11 unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF (see comment) 299 70.0 91/130 nt 8 8 X 8.8.X [1.17.8.X] null - No rearrangement found Low V-REGION identity (70,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaacgtggtcatcgcctgcctggtccagggcctcttccccca +1415 JY8QFUQ01A3VDJ unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +1416 JY8QFUQ01CNXZU No results +1417 JY8QFUQ01BLPYK No results +1418 JY8QFUQ01BOG7A productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + tctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +1419 JY8QFUQ01B21I3 No results +1420 JY8QFUQ01CD61F unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F 144 59.26 64/108 nt 8 8 X 8.8.X [0.17.2.X] null + No rearrangement found cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaagggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1421 JY8QFUQ01A2TDY No results +1422 JY8QFUQ01C8YUG productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame + tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1423 JY8QFUQ01AUCXY No results +1424 JY8QFUQ01CWYOD unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. gtctggattcacctttagtgattatgccttgagctgggtccgccagactcccgggaaggggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgagagatccgggaaattattggggatactattatgactcttgggggcctggggaaacccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1425 JY8QFUQ01C9RSP No results +1426 JY8QFUQ01A5ZE0 No results +1427 JY8QFUQ01CQUPE No results +1428 JY8QFUQ01AJALL unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDNYGDYW# out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1429 JY8QFUQ01C42EK No results +1430 JY8QFUQ01C9WTB No results +1431 JY8QFUQ01A2U9H unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 774 83.87 182/217 nt Homsap IGHJ2*01 F (see comment) 32 63.16 12/19 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttcccgaaccggtgacggtgtcgtggaactcag +1432 JY8QFUQ01BTOWM unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 382 76.12 102/134 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (76,12% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +1433 JY8QFUQ01AG2OG productive Homsap IGHV3-64*02 F (see comment) 769 84.26 182/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-9*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVRGRPMAGFHGILYDNW in-frame + Low V-REGION identity (84,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggatttagtatcagtaattatggtattcactgggtccgccaggctccagggaggggactggaacttgtttcagctattaccaacaatgcgcatagtgtagtctatgtagactctgtgaagggcagattcatcatctccagagactattccaagaacacgttgtatcttcaaatgggcagactgagaccagaagacacggctgtgtactactgtgtcagagggcggcctatggctggctttcatggaatcctttatgacaactggggcctgggaacccttgtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1434 JY8QFUQ01C26A4 No results +1435 JY8QFUQ01CB0O0 No results +1436 JY8QFUQ01DL2NW No results +1437 JY8QFUQ01DUBH3 unknown (see comment) Homsap IGHV3-22*01 P, or Homsap IGHV3-22*02 P 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons tgtctggattctccgtcagtttcaactacatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +1438 JY8QFUQ01CLXH8 No results +1439 JY8QFUQ01AEUEN unproductive (see comment) Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CATSPLR*LLGRT#YW out-of-frame - stop codons cctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctcccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +1440 JY8QFUQ01AUSWA unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 273 69.11 85/123 nt 8 8 X 8.8.X [1.17.7.X] null + No rearrangement found Low V-REGION identity (69,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +1441 JY8QFUQ01CTJC0 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +1442 JY8QFUQ01BI9UV No results +1443 JY8QFUQ01BVNHA No results +1444 JY8QFUQ01BDGPP No results +1445 JY8QFUQ01CHY6B No results +1446 JY8QFUQ01DRO6Z productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 973 92.11 210/228 nt 91.67 209/228 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [2.17.38.11] CARGGNYYDSGGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); tctccgggggacagtgtctctagcagcagtgttgTtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcgaataactatcaagccagacgcatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtatattactgtgcaagagggggtaattactatgatagtggtggtcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +1447 JY8QFUQ01DULSH No results +1448 JY8QFUQ01BVM0S No results +1449 JY8QFUQ01DKWYM No results +1450 JY8QFUQ01DD498 No results +1451 JY8QFUQ01BBVFC productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); ctctggattcacctttactagttacagtttcaactgggtccgccCaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +1452 JY8QFUQ01ATQS0 unknown (see comment) Homsap IGHV3-11*01 F (see comment) 633 77.1 165/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01ATQS0 ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (77,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +1453 JY8QFUQ01DJJ2U No results +1454 JY8QFUQ01BLKB1 No results +1455 JY8QFUQ01ARGE6 No results +1456 JY8QFUQ01BUAN5 No results +1457 JY8QFUQ01DMFF2 No results +1458 JY8QFUQ01DEVVA No results +1459 JY8QFUQ01AX6JI No results +1460 JY8QFUQ01CYZSJ productive Homsap IGHV3-11*01 F 823 87.04 188/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-7*01 F 1 8 8 15 8.8.15 [1.17.38.11] CVRESRSWTGSTLPAYW in-frame + tctggattcaccttcagtgactattacatgagttggtaccgccaggctccaggtcaggggctggagtggctttcatatataagtcaaactggcaaaaccacatacttcgcagactctgtgaagggccgattcaccatctccagggacaatgccaagacatcagtgtttctgcaaatgaacagcctgagagttgacgacacggccgtgtatttttgtgtgagagaatctaggagttggactggaagtacacttccagcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +1461 JY8QFUQ01C2H4R No results +1462 JY8QFUQ01A2DHA No results +1463 JY8QFUQ01CCUUB No results +1464 JY8QFUQ01A6213 unproductive Homsap IGHV1-3*01 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [0.17.38.11] CARDGESLGGD#FDYW out-of-frame + tggatacaccttcagtaattatgctatacattggttgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctggcacgggtaacacaaaatattcacagaagttccagggcagagtcaccattaccagggacacagccgcgaccacagcctacatggaattgagcagcctgaaatctgaggacacggccgtgtattactgtgcgagagatggggagtcactgggaggcgactatttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1465 JY8QFUQ01BMD3G unknown (see comment) Homsap IGHV1-2*02 F 491 87.4 111/127 nt 86.61 110/127 nt 7 8 X 7.8.X [0.17.9.X] null + No rearrangement found in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift) tggatacatttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcaggg +1466 JY8QFUQ01CDBCN unknown (see comment) Homsap IGHV3-66*02 F (see comment) 687 79.91 171/214 nt 8 7 X 8.7.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1467 JY8QFUQ01DF0MT No results +1468 JY8QFUQ01CF4HL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 401 89.0 89/100 nt 8 7 X 8.7.X [1.17.X.X] null + No rearrangement found ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagggtgttgaca +1469 JY8QFUQ01C8D76 No results +1470 JY8QFUQ01DW98C No results +1471 JY8QFUQ01C6KJV No results +1472 JY8QFUQ01CT0HD productive (see comment) Homsap IGHV3-7*02 F 917 92.09 198/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.16.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 33 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggagccctggtcaccgtcttctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +1473 JY8QFUQ01BZ11O No results +1474 JY8QFUQ01C83Q9 No results +1475 JY8QFUQ01CUE0P No results +1476 JY8QFUQ01C0R3Y No results +1477 JY8QFUQ01DSN92 productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame + ctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttgcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca +1478 JY8QFUQ01DNURL No results +1479 JY8QFUQ01BL2YO productive Homsap IGHV3-11*01 F 855 88.48 192/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVDIRLGDWFFDLW in-frame + ctctggattcaccttcagtgaccactacatgagctgggtccgccaggctccggggaagggtctggaatggatctcatatatcagtacaagtggtaatatggtttattacgcggactctgtgaagggccgattcaccgtctccagggacaacaccaagagctcactgtatctgcaaatgaacggcctcagagtcgaggacacggccgtctattactgtgtcgacataagactgggagattggttcttcgatctctggggccgtggcaccctggtaactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1480 JY8QFUQ01AL3MP No results +1481 JY8QFUQ01AJN29 No results +1482 JY8QFUQ01BC3V3 No results +1483 JY8QFUQ01C7F7K No results +1484 JY8QFUQ01AVMY4 No results +1485 JY8QFUQ01C8W2Q No results +1486 JY8QFUQ01CRZ6P No results +1487 JY8QFUQ01CMH9H No results +1488 JY8QFUQ01AX1TT No results +1489 JY8QFUQ01B6TW6 productive (see comment) Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 388 91.4 85/93 nt 89.25 83/93 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD5-18*01 F 3 X X 15 X.X.15 [X.X.31.11] CARSDEEYSYGDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'ACTAT' (5 nucleotides at position 21 to 25 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 90 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift) gtctggattcaccttcagtaACTATgagacaattccaagaacacgctgtatctgcaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatcggacgaggaatacagctatggggatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1490 JY8QFUQ01A1UND productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) gcctcctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1491 JY8QFUQ01ADO15 No results +1492 JY8QFUQ01AHJ9R unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag +1493 JY8QFUQ01DTXW3 No results +1494 JY8QFUQ01ATI6H No results +1495 JY8QFUQ01AOK66 productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaatagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1496 JY8QFUQ01A6GAE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVKEDHDSGLRVLLEW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 51 of V-REGION: 'AG' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift); ctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggaggggcgtggaAGgtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1497 JY8QFUQ01BIWEF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggttaaggactacttccccgaaccggtgacggtgtcgtggaact +1498 JY8QFUQ01A50M4 unproductive Homsap IGHV3-30*08 F, or Homsap IGHV3-30*16 F 918 91.71 199/217 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGKAGHTHYGLDV## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctgcattcaccttcagtagttatgctatgcactgggtccgccaggccccaggcaaggggctagagtgggtggcagttatatcaaatgatggaaattataacgactatgcagactccgtgaaggggcgattcaccatttccagagacaactccaagaacacgctatttctacaaatgaatagcctgagagttgaggacacggctgtctataactgtgcgagaggaaaggctggccatacccactacggattggacgtctggggccaaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1499 JY8QFUQ01C8L2Z No results +1500 JY8QFUQ01BRQW6 unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 105 100.0 21/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattcactttcagtaa +1501 JY8QFUQ01DNLCD No results +1502 JY8QFUQ01DK6B2 No results +1503 JY8QFUQ01CSULX No results +1504 JY8QFUQ01AR3XO productive (see comment) Homsap IGHV3-7*03 F 927 92.17 200/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'GA' (2 nucleotides at position 65 to 66 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); ctctggatttagctttagaaccttttggatgagctgggtccgccaggctccagggaggggcgtgGAgagtgggtggccaaTcataaagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1505 JY8QFUQ01DFEJE No results +1506 JY8QFUQ01DMEUX No results +1507 JY8QFUQ01C0DJQ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 387 76.3 103/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (76,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +1508 JY8QFUQ01CT3AM productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1509 JY8QFUQ01BBQA5 No results +1510 JY8QFUQ01AZSN7 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 98 60.0 42/70 nt 58.57 41/70 nt 8 X X 8.X.X [0.14.X.X] null - No rearrangement found in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 38 in the user submitted sequence), (cause frameshift) ctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1511 JY8QFUQ01AT9ZL No results +1512 JY8QFUQ01CYS4U unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 270 68.25 86/126 nt 8 8 X 8.8.X [1.17.7.X] null - No rearrangement found Low V-REGION identity (68,25% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +1513 JY8QFUQ01CCP15 No results +1514 JY8QFUQ01BB2S8 No results +1515 JY8QFUQ01DSXCD No results +1516 JY8QFUQ01BNWTF No results +1517 JY8QFUQ01BZVYZ No results +1518 JY8QFUQ01C7KGD No results +1519 JY8QFUQ01C4PQJ No results +1520 JY8QFUQ01CTOHD No results +1521 JY8QFUQ01AVF2G No results +1522 JY8QFUQ01C9SAD productive (see comment) Homsap IGHV4-39*03 F, or Homsap IGHV4-39*07 F 870 88.58 194/219 nt 87.67 192/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'C' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggtggctccatcaacagtggtagttatcactggggCctggatccgccagTcccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +1523 JY8QFUQ01CTJGE productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +1524 JY8QFUQ01BBTKL No results +1525 JY8QFUQ01C4OPG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1526 JY8QFUQ01CXEZM No results +1527 JY8QFUQ01DMH48 productive Homsap IGHV1-24*01 F 988 96.24 205/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame - ggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +1528 JY8QFUQ01DW6RS No results +1529 JY8QFUQ01CWB23 No results +1530 JY8QFUQ01DWHTO productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 682 95.33 143/150 nt 94.67 142/150 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 X 8 8.X.8 [1.15.26.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 66 nucleotides (from position 73 in the user submitted sequence), (do not cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacacaccccccaacgatgggaacgtggtccgtcgcatgcctggtccagggccttcttcccccga +1531 JY8QFUQ01CZYGW No results +1532 JY8QFUQ01AL6QG No results +1533 JY8QFUQ01CGTYC No results +1534 JY8QFUQ01A7RTJ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 492 84.06 116/138 nt 83.33 115/138 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (84,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggcGtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc +1535 JY8QFUQ01C8WKL unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 92 51.8 72/139 nt 10 9 X 10.9.X [1.17.9.X] null - No rearrangement found stop codons ctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1536 JY8QFUQ01CQAGH No results +1537 JY8QFUQ01AIGGL No results +1538 JY8QFUQ01B0I9T No results +1539 JY8QFUQ01BS4TM unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F 197 57.4 97/169 nt 8 8 X 8.8.X [1.17.22.X] null + No rearrangement found tctggattcaccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaatggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +1540 JY8QFUQ01C233A unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*03 F or Homsap IGHV4-34*04 F or Homsap IGHV4-34*06 F or Homsap IGHV4-34*07 F or Homsap IGHV4-34*09 F or Homsap IGHV4-34*10 F or Homsap IGHV4-34*12 F 98 58.23 46/79 nt 8 X X 8.X.X [1.17.X.X] null - No rearrangement found ctatggtgggtccttcagtacttactactggacatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1541 JY8QFUQ01AEBZX unknown (see comment) Homsap IGHV3-30*19 F (see comment) 298 74.55 82/110 nt 8 8 X 8.8.X [1.17.2.X] null + No rearrangement found Low V-REGION identity (74,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcaacttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagtcatcgcctgcctggtccagggcttcttccccca +1542 JY8QFUQ01DHO1I No results +1543 JY8QFUQ01DVHFD productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +1544 JY8QFUQ01DG1MM No results +1545 JY8QFUQ01C6NYA No results +1546 JY8QFUQ01AOIZ2 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 876 96.77 180/186 nt 8 8 X 8.8.X [1.17.27.X] null + No rearrangement found ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcca +1547 JY8QFUQ01BF3C4 No results +1548 JY8QFUQ01AF4P6 No results +1549 JY8QFUQ01AHA6F No results +1550 JY8QFUQ01B1R1V No results +1551 JY8QFUQ01AX41Q No results +1552 JY8QFUQ01AIX26 No results +1553 JY8QFUQ01A9NCZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 867 89.72 192/214 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVSDLAGQKGSW in-frame - aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1554 JY8QFUQ01C4MF5 No results +1555 JY8QFUQ01A8DGZ No results +1556 JY8QFUQ01ADA0I No results +1557 JY8QFUQ01CYDVX No results +1558 JY8QFUQ01CHSNE No results +1559 JY8QFUQ01DEI8T No results +1560 JY8QFUQ01A5AEL No results +1561 JY8QFUQ01BY3ME No results +1562 JY8QFUQ01BZ1UD No results +1563 JY8QFUQ01CSG2N No results +1564 JY8QFUQ01CX7CX No results +1565 JY8QFUQ01CPO8G No results +1566 JY8QFUQ01C4AN6 No results +1567 JY8QFUQ01A7DEU No results +1568 JY8QFUQ01AM9GW unproductive Homsap IGHV3-11*01 F 977 94.5 206/218 nt Homsap IGHJ2*01 F (see comment) 94 64.15 34/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARRRDYGDYGDGFDYW# out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactgggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1569 JY8QFUQ01CR49L productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +1570 JY8QFUQ01B506K unknown (see comment) Homsap IGHV4-61*06 ORF (see comment) 328 61.11 132/216 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (61,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +1571 JY8QFUQ01BP7DL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARGEFYYETSGRRGFDYW in-frame + ctctggattcaccttcactacctcctggatgcactgggtccgccaagctccagggaaggggctaatgtgggtctcacgtgtgaataaggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaccacgctgtacttggaaatgaacagtctgagagtcgaggacacggctatgtattattgtgcaagaggagaattttattatgaaactagtggtcgaaggggttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1572 JY8QFUQ01CS6JH productive Homsap IGHV3-7*01 F 922 92.13 199/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame + tctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcgggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1573 JY8QFUQ01DC99E No results +1574 JY8QFUQ01CDR1Q No results +1575 JY8QFUQ01BWF7R No results +1576 JY8QFUQ01AF5F2 unknown (see comment) Homsap IGHV3-7*01 F 900 90.78 197/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1577 JY8QFUQ01CJG83 No results +1578 JY8QFUQ01AQA2P No results +1579 JY8QFUQ01C3DCT unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 85 51.49 69/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcacctttaacctctatgtcatgcactggttccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1580 JY8QFUQ01CEDL3 No results +1581 JY8QFUQ01BPHP1 No results +1582 JY8QFUQ01DC6L2 productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame + ctctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca +1583 JY8QFUQ01AMF2G No results +1584 JY8QFUQ01DSXER productive Homsap IGHV3-7*03 F 837 87.56 190/217 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcacttttagtgactattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1585 JY8QFUQ01DESV3 No results +1586 JY8QFUQ01CCPG5 No results +1587 JY8QFUQ01AQXSC unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 670 78.7 170/216 nt 78.24 169/216 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found Low V-REGION identity (78,70% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +1588 JY8QFUQ01DQ1Q4 productive (see comment) Homsap IGHV4-61*02 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 9 7 15 9.7.15 [1.17.38.11] CARGRTVVTVVDYVDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) tctctggtgctccatcagcagtggtagtttctacCtggagctggatccggcagcccgccgggaagggactggagtggatggggcgtgtctatgccagtggaaccaccaagttcaacccctccctcaagagtcgagtcactttatcagtagacacgtccaagaaccagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacgaacggtggtgactgttgttgactacgttgacttttggggtcagggagtcctggtcaacgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1589 JY8QFUQ01A40Z9 No results +1590 JY8QFUQ01BT13P unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 998 96.28 207/215 nt 95.81 206/215 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDNYGDY## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1591 JY8QFUQ01B42CS No results +1592 JY8QFUQ01DCAUV unknown (see comment) Homsap IGHV3-13*02 F 82 51.56 66/128 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found tctggattcagcttaagttcttatggcatgaactgggtccgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaact +1593 JY8QFUQ01BOEMI No results +1594 JY8QFUQ01DGRKS No results +1595 JY8QFUQ01CYSQX unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 709 81.69 174/213 nt 81.22 173/213 nt Homsap IGHJ2*01 F 103 66.04 35/53 nt Homsap IGHD1-7*01 F 2 8 7 X 8.7.X [1.17.37.11] CARLDGHFD#LG out-of-frame + Low V-REGION identity (81,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 130 in the user submitted sequence), (cause frameshift) ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctgggggcccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +1596 JY8QFUQ01CL5D9 No results +1597 JY8QFUQ01C7A04 unknown (see comment) Homsap IGHV1-3*01 F (see comment) 340 61.97 132/213 nt 61.5 131/213 nt Homsap IGHJ1*01 F, or Homsap IGHJ4*03 F or Homsap IGHJ5*02 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.16.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (61,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) tggatacagcttcactaactacaatatccattgggtgcgccaggccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1598 JY8QFUQ01A115T No results +1599 JY8QFUQ01DC99U No results +1600 JY8QFUQ01C7LLU No results +1601 JY8QFUQ01BSUYS No results +1602 JY8QFUQ01BWI1R No results +1603 JY8QFUQ01BD39D No results +1604 JY8QFUQ01ANEJ0 No results +1605 JY8QFUQ01CZFYF unknown (see comment) Homsap IGHV3-38-3*01 ORF 87 51.94 67/129 nt 8 7 X 8.7.X [1.17.10.X] null - No rearrangement found stop codons gtctggattctccgtcagtttcaactacatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccca +1606 JY8QFUQ01DSJJ1 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 624 93.66 133/142 nt 91.55 130/142 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 7 1 10 7.1.10 [1.X.37.11] CVSDLAGQKGFW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01DSJJ1 ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'T' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 38 of V-REGION: 75 nucleotides (from position 27 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) cctcaggattcaccttcagtagctacacagatcacgcggactccgtgaaTgggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1607 JY8QFUQ01B8BQK No results +1608 JY8QFUQ01AE5UH No results +1609 JY8QFUQ01DSSRA No results +1610 JY8QFUQ01AKT2V No results +1611 JY8QFUQ01AT43H productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.16.38.11] CSKDTFGREDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 2 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattctccgtcagtaattactggatgcactgggtccgccaggctccagggagggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1612 JY8QFUQ01DMC3P productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKINNDFGDYDWFDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactgggggcaccgactccaaccCcctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaatcaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccgag +1613 JY8QFUQ01BCGX5 unproductive Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 651 78.04 167/214 nt Homsap IGHJ2*01 F 27 61.11 11/18 nt 8 8 X 8.8.X [0.17.38.6] RTGD (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Low V-REGION identity (78,04% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggccctgggctgcctggtcaaggactacttccccgaaccggtgacagtgtcgtggaactcag +1614 JY8QFUQ01CSQQE productive Homsap IGHV4-61*02 F 987 94.55 208/220 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame + ctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +1615 JY8QFUQ01BDYZI No results +1616 JY8QFUQ01DAF6H unknown (see comment) Homsap IGHV3-7*02 F 108 59.26 48/81 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +1617 JY8QFUQ01A7MDG No results +1618 JY8QFUQ01BA4CQ No results +1619 JY8QFUQ01CATXG unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F or Homsap IGHV3-9*01 F or Homsap IGHV3-9*03 F 116 62.86 44/70 nt 61.43 43/70 nt 8 X X 8.X.X [1.14.X.X] null - No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 48 in the user submitted sequence), (do not cause frameshift) ctctggattccggtttgatgattatgccatacattgggttcgcctgcctggtccagggcttcttccccca +1620 JY8QFUQ01A76UO No results +1621 JY8QFUQ01A9J93 No results +1622 JY8QFUQ01A8DDZ No results +1623 JY8QFUQ01DXIJH No results +1624 JY8QFUQ01BGTEX No results +1625 JY8QFUQ01DGTT9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +1626 JY8QFUQ01BYDQM No results +1627 JY8QFUQ01BB2G6 No results +1628 JY8QFUQ01BGV4K unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 190 76.92 50/65 nt 8 X X 8.X.X [0.13.X.X] null - No rearrangement found ctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggcttcttccccca +1629 JY8QFUQ01A8XJR productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 997 94.59 210/222 nt 93.69 208/222 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 199 to 199 in the user submitted sequence), (cause frameshift); tctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaaGtatgctgtatctgcaattgaacagcctgaaaacCcgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +1630 JY8QFUQ01BVKDE No results +1631 JY8QFUQ01BBFMH No results +1632 JY8QFUQ01CSY85 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 93 52.27 69/132 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons tctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +1633 JY8QFUQ01AJ1SS unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 100 53.12 68/128 nt 8 8 X 8.8.X [1.17.8.X] null + No rearrangement found stop codons ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt +1634 JY8QFUQ01CJL2W No results +1635 JY8QFUQ01CBN2X No results +1636 JY8QFUQ01CXT5I No results +1637 JY8QFUQ01DW8QQ No results +1638 JY8QFUQ01C466A No results +1639 JY8QFUQ01A6H47 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 637 82.26 153/186 nt 81.72 152/186 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD4-11*01 ORF 3 X 8 X X.8.X [X.16.38.11] DSRNPRV# out-of-frame + Low V-REGION identity (82,26% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 28 in the user submitted sequence), (cause frameshift) gagtgggtgccgccaggctccagggaagggctggagtgggtctcagggctttgtggaagtgctcctaccacacactacgcagactccgtgaagggccggttcagcatctccagagacctctccaagaatgttctgtttctgcaaacgagcagcctgagagccgaggacacgaccgttttttctgactccagaaatcccagggtaggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccatggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaacctcaggc +1640 JY8QFUQ01CB3G5 No results +1641 JY8QFUQ01BNQ9Y No results +1642 JY8QFUQ01ABDNP productive (see comment) Homsap IGHV3-7*01 F 805 86.11 186/216 nt 85.19 184/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [1.17.38.11] CARGDGYNFGGLDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'GA' (2 nucleotides at position 64 to 65 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); tctggatttagctttagaaccttttggatgagctgggtccgccaggctccagggaggggcgtgGAgagtgggtggccaaTcataaagtcagatggaagtgacaaatggtatgtggactccgtgaggggccgatccatcatttccagagacgattctaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +1643 JY8QFUQ01BLJQY No results +1644 JY8QFUQ01DNQRU unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +1645 JY8QFUQ01AG942 unknown (see comment) Homsap IGHV3-23*05 F 97 54.81 57/104 nt 8 8 X 8.8.X [1.17.X.X] null + No rearrangement found stop codons ctctggattcgtctttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1646 JY8QFUQ01AWAV5 No results +1647 JY8QFUQ01AEHLA No results +1648 JY8QFUQ01CCCUV No results +1649 JY8QFUQ01A8KZQ productive Homsap IGHV3-7*03 F 837 87.56 190/217 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcacttttagtgactattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1650 JY8QFUQ01C77C5 No results +1651 JY8QFUQ01CFYO5 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 55 100.0 11/11 nt 2 X X 2.X.X [1.X.X.X] null + No rearrangement found ctctggattca +1652 JY8QFUQ01AW8AK No results +1653 JY8QFUQ01B7Y0I No results +1654 JY8QFUQ01BGOA2 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 604 79.58 152/191 nt 8 8 X 8.8.X [2.17.28.X] null - No rearrangement found Low V-REGION identity (79,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacgcctgcctggtccagggcttcttccccca +1655 JY8QFUQ01ASF1C unknown (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 929 91.4 202/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggagcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagagcatccccgaccagccccaaggctcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +1656 JY8QFUQ01DHAVX No results +1657 JY8QFUQ01DJLNB No results +1658 JY8QFUQ01DSWRX No results +1659 JY8QFUQ01CU3Q6 No results +1660 JY8QFUQ01DDW01 No results +1661 JY8QFUQ01BWZ4E No results +1662 JY8QFUQ01CZB0R No results +1663 JY8QFUQ01DO1CE No results +1664 JY8QFUQ01BYRY4 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 769 83.8 181/216 nt Homsap IGHJ2*01 F (see comment) 32 63.16 12/19 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttcccgaaccggtgacggtgtcgtggaactcag +1665 JY8QFUQ01DKO56 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [2.17.38.11] CANASPV*LE#YFYYYGMDVW out-of-frame - stop codons gcctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctcccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1666 JY8QFUQ01BMXOK unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1030 97.69 211/216 nt 97.22 210/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattaGgtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaagccctggctnaccgtctcctcagcatccccgaccagccccaaggtcttcccgntgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggctccagggcttcttccc +1667 JY8QFUQ01ALR6B No results +1668 JY8QFUQ01A9M5C productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt 94.5 206/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [2.16.38.11] CARDPVGISGSVNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'G' (1 nucleotides at position 138 to 138 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaagggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccGatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1669 JY8QFUQ01A6VX5 No results +1670 JY8QFUQ01CTAKI unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 213 80.3 53/66 nt 8 X X 8.X.X [1.12.X.X] null - No rearrangement found Low V-REGION identity (80,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggcttcttcccca +1671 JY8QFUQ01BHD1H No results +1672 JY8QFUQ01BBU8N No results +1673 JY8QFUQ01DJWHU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +1674 JY8QFUQ01BSNEK No results +1675 JY8QFUQ01B1925 No results +1676 JY8QFUQ01BFQJR No results +1677 JY8QFUQ01A765R unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 494 92.17 106/115 nt 8 8 X 8.8.X [0.17.5.X] null + No rearrangement found tggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagaccca +1678 JY8QFUQ01C34PH unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 112 53.73 72/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1679 JY8QFUQ01CZTSH No results +1680 JY8QFUQ01C6A2R No results +1681 JY8QFUQ01DWH6E unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 167 94.59 35/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcacctttggttattatggcatgagctgg +1682 JY8QFUQ01DVPDB unproductive (see comment) Homsap IGHV4-61*01 F 947 92.31 204/221 nt 91.86 203/221 nt Homsap IGHJ5*02 F 97 64.71 33/51 nt Homsap IGHD6-6*01 F 2 10 7 X 10.7.X [1.17.38.11] CTRGAVXL*QPV# out-of-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcggtagtactaactactggagctggattcggcagcCccccagggaagggactggaattcattgggtatatctattccagtgggaggaccaactacaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccagttctccctgaggctggcgtctgtgaccgctgcggacacggccgtgtattactgtacgaggggggcagtacanttatgacagcccgtggggacaggggacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1683 JY8QFUQ01BBU79 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 139 63.75 51/80 nt 8 X X 8.X.X [1.17.X.X] null + No rearrangement found stop codons tctggattcacctttagcagctatgccatgagctgggtcaaggactacttcccgaaccggtgacggtgtcgtggaactca +1684 JY8QFUQ01CE73H No results +1685 JY8QFUQ01AV27O No results +1686 JY8QFUQ01B8EZR No results +1687 JY8QFUQ01AOGA6 No results +1688 JY8QFUQ01AFRYT No results +1689 JY8QFUQ01C98A9 productive Homsap IGHV1-18*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARENYYTSGIHSGFRHW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggttacatctttaccacctatggtatcagttgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcaacacttacaatggtaacacgaactatggacagaggatccagggcagagtcaccatgaccacagacacatccacgagcacagcctacatggagctgaggagcctgagatctgacgacacggccgtatattattgtgcgagagaaaactactatacttcgggaattcattccggcttcaggcactggggccagggaaccctggtcaccgtctcctcagctccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1690 JY8QFUQ01AHYWT productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 678 79.91 171/214 nt 78.97 169/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 71 of V-REGION: 'C' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'AGT' (3 nucleotides at position 137 to 139 in the user submitted sequence), (do not cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccCgtgaggggcgggcttatcgaAGTctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1691 JY8QFUQ01AZS8E unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 80 51.13 68/133 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggatccaccgtcagtacctatagcctgaactgggtccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +1692 JY8QFUQ01CFTY8 No results +1693 JY8QFUQ01DTGVP No results +1694 JY8QFUQ01A6M8L No results +1695 JY8QFUQ01BIK9K No results +1696 JY8QFUQ01CQTRT No results +1697 JY8QFUQ01DMOXH No results +1698 JY8QFUQ01AFK77 No results +1699 JY8QFUQ01DC0HE No results +1700 JY8QFUQ01BSGS4 No results +1701 JY8QFUQ01C0P59 No results +1702 JY8QFUQ01CMY3L No results +1703 JY8QFUQ01DSU07 No results +1704 JY8QFUQ01CHJWZ unknown (see comment) Homsap IGHV3-66*02 F 748 92.49 160/173 nt 8 7 X 8.7.X [4.17.21.X] null + No rearrangement found tctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgta +1705 JY8QFUQ01BR08D productive (see comment) Homsap IGHV3-48*04 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 76 of V-REGION: 'G' (1 nucleotides at position 133 to 133 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgactatagcatgaactgggtccgccagactccagggaagggggtggagtggatttcatacatcggccgtggtggtgatgggatatactacgcggactccgtggaggaccgattGcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1706 JY8QFUQ01BPJB6 No results +1707 JY8QFUQ01BI4C1 No results +1708 JY8QFUQ01DF3F1 No results +1709 JY8QFUQ01BNFPE No results +1710 JY8QFUQ01DK75T No results +1711 JY8QFUQ01BA4G5 productive (see comment) Homsap IGHV3-11*01 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1712 JY8QFUQ01C8JNJ No results +1713 JY8QFUQ01AJRAI No results +1714 JY8QFUQ01C5U0P No results +1715 JY8QFUQ01DSUT3 No results +1716 JY8QFUQ01A501N No results +1717 JY8QFUQ01AKC7U No results +1718 JY8QFUQ01CUV5O unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F (see comment) 366 67.82 118/174 nt 8 10 X 8.10.X [1.17.21.X] null - No rearrangement found Low V-REGION identity (67,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1719 JY8QFUQ01B0PMZ No results +1720 JY8QFUQ01CCGCT unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +1721 JY8QFUQ01BWFT2 No results +1722 JY8QFUQ01DKW91 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +1723 JY8QFUQ01A86GB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-7*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKVFQVPGEHHFYYFGMNVW in-frame - cctctggattcatgtttaggaactatgccatgagttgggtccgccaggctccagggagggggctggagtgggtctcaactattagcaataatggaagccacacatactacgcagactccgtcaagggccggttcaccatctccagagacaattccaagaacacggtgtatatgcagatgaacaggctgagagtcgaggagacggccctgtactactgtgcgaaagtcttccaggtgcctggcgagcaccacttctactacttcggaatgaatgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +1724 JY8QFUQ01A7BSR No results +1725 JY8QFUQ01AGMEL No results +1726 JY8QFUQ01CTF5B unknown (see comment) Homsap IGHV3-23*05 F 87 51.94 67/129 nt 8 8 X 8.8.X [1.17.8.X] null - No rearrangement found stop codons cctctggatacagttttaacagttatgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccaggcttcttcc +1727 JY8QFUQ01AU61S productive Homsap IGHV1-24*01 F 957 94.39 202/214 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD3-16*01 F 2 8 8 11 8.8.11 [0.17.38.11] CVGDVGWGYPQGW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cggatacaccctcaatgaattatccatgcactgggtgcgacagactcctggaaaagggcttgagtcgatgggcggttttgatcctgaatatggtaaaacaatctacgcgcagaagttccagggcagagtcaccatgaccgaggacacatctgcagacacagcctacatggagttgagaagcctgagatttgaggacacggccgtgtattattgtgtcggagatgtcggctggggatacccccaaggctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1728 JY8QFUQ01A2WKZ No results +1729 JY8QFUQ01AGQ6F No results +1730 JY8QFUQ01BOLV9 No results +1731 JY8QFUQ01CHRWV No results +1732 JY8QFUQ01BZMVP No results +1733 JY8QFUQ01BUEFY No results +1734 JY8QFUQ01DBD2S unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F (see comment) 355 63.59 131/206 nt 63.11 130/206 nt 8 8 X 8.8.X [1.17.34.X] null - No rearrangement found Low V-REGION identity (63,59% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); gtctggattcaAttttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtcaaaaatattacgcagactcagtgaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1735 JY8QFUQ01CFU2I No results +1736 JY8QFUQ01BDDZ2 productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1737 JY8QFUQ01BHBIU No results +1738 JY8QFUQ01CURR2 No results +1739 JY8QFUQ01C53TF unproductive Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDGPPYLYGSHGNSFDQ## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggcccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1740 JY8QFUQ01CUUA0 unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +1741 JY8QFUQ01C0UXJ No results +1742 JY8QFUQ01A358V No results +1743 JY8QFUQ01CEAGF No results +1744 JY8QFUQ01CVR09 unproductive Homsap IGHV3-21*04 F 990 95.39 207/217 nt 94.47 205/217 nt Homsap IGHJ6*02 F 128 68.97 40/58 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARAVSNQVDVW# out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); ctctggattcgccGttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagAttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctgggggcccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1745 JY8QFUQ01DQ2MG No results +1746 JY8QFUQ01DLEQI No results +1747 JY8QFUQ01CUKWF No results +1748 JY8QFUQ01AL7F8 No results +1749 JY8QFUQ01A702R productive Homsap IGHV3-48*02 F (see comment) 724 81.48 176/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1750 JY8QFUQ01DHU2N productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 285 82.35 70/85 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame - Low V-REGION identity (82,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1751 JY8QFUQ01DPCAF No results +1752 JY8QFUQ01B26JL productive Homsap IGHV3-9*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDRKGSNWYYFENW in-frame - ctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1753 JY8QFUQ01BPXVZ No results +1754 JY8QFUQ01C3YIQ No results +1755 JY8QFUQ01AD96J unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 709 79.73 177/222 nt 8 10 X 8.10.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (79,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcactgtcaataacgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgatggcgggacagcagactacgctccatttgtggacgacagattcaccatttcaacagatgattcaaaaatcacgttgtatctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +1756 JY8QFUQ01DCKY3 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 901 90.41 198/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDLYGADDLW in-frame - acctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1757 JY8QFUQ01BSCCC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 94 of V-REGION: 'A' (1 nucleotides at position 187 to 187 in the user submitted sequence), (cause frameshift); ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctAggggcccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctcggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +1758 JY8QFUQ01BTY9A No results +1759 JY8QFUQ01ABU7T No results +1760 JY8QFUQ01DQFTI No results +1761 JY8QFUQ01CZ8S7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1762 JY8QFUQ01B0QD1 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 96.32 183/190 nt 95.26 181/190 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.29.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 94 of V-REGION: 25 nucleotides (from position 185 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtcttactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1763 JY8QFUQ01CUVTH unknown (see comment) Homsap IGHV1-NL1*01 P 90 56.79 46/81 nt 2 X X 2.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagagac +1764 JY8QFUQ01BEARQ No results +1765 JY8QFUQ01DC4QI productive Homsap IGHV3-48*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARESTWEFTPDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcagtttcagtgactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagttctagtagtaccctatattatgcagactctgtgaagggccgattcaccgtctccagagacaatgacaagagttctctgtatctgcaaatgaccggcctgagagccgaagacacggcgacttattactgtgcgagagagtcgacgtgggaatttactcctgactcctggggcccggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccaggcccagcatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag +1766 JY8QFUQ01CL5V0 productive (see comment) Homsap IGHV3-7*01 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.37.11] CSRLLEEW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaagcgtggtcgtcgcatgcctggtccagggcttcttccccc +1767 JY8QFUQ01DALFI No results +1768 JY8QFUQ01ALIFQ No results +1769 JY8QFUQ01AO96D unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 817 87.32 186/213 nt 86.38 184/213 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-10*02 F 2 8 7 X 8.7.X [1.16.38.11] CAKESLFGESS#YYFDDW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) ctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaagggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggtttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctgttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1770 JY8QFUQ01BYQY5 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +1771 JY8QFUQ01A015U productive (see comment) Homsap IGHV3-30*13 F (see comment) 228 77.22 61/79 nt 75.95 60/79 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 1 X X 14 X.X.14 [X.X.26.11] CAKDLFQVSTTYFDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (77,22% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 87 of V-REGION: 12 nucleotides (from position 38 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcagtgactatcacatgtactggatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1772 JY8QFUQ01DIXGW unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 639 76.96 167/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (76,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1773 JY8QFUQ01ATDNN No results +1774 JY8QFUQ01A5728 No results +1775 JY8QFUQ01AZY3T unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 245 58.55 113/193 nt 8 8 X 8.8.X [1.17.30.X] null + No rearrangement found Low V-REGION identity (58,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +1776 JY8QFUQ01BZ5SX productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 907 90.09 200/222 nt 89.19 198/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaAggggctggagtggaTttgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1777 JY8QFUQ01DOTS5 No results +1778 JY8QFUQ01B8BR0 No results +1779 JY8QFUQ01A9NA9 unknown (see comment) Homsap IGHV3-66*02 F 754 92.05 162/176 nt 8 7 X 8.7.X [5.17.21.X] null - No rearrangement found gcctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgta +1780 JY8QFUQ01CV75P No results +1781 JY8QFUQ01BCGSW No results +1782 JY8QFUQ01A6XI0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +1783 JY8QFUQ01DSK9X No results +1784 JY8QFUQ01DTS0X No results +1785 JY8QFUQ01B2SD9 No results +1786 JY8QFUQ01DITLY productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacatactGggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1787 JY8QFUQ01CUUSO unknown (see comment) Homsap IGHV3-7*02 F 109 59.04 49/83 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1788 JY8QFUQ01ARL85 No results +1789 JY8QFUQ01DCNFO productive (see comment) Homsap IGHV1-69*06 F, or Homsap IGHV1-69*14 F 993 96.26 206/214 nt 94.86 203/214 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD5-12*01 F 3 8 8 19 8.8.19 [0.17.38.11] CAREVSGYDLTVAGWWGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'T' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); tggaggcaccttcagcagctatgctatcagctgggtgcgacaggcccctggacaagggcttgagtggatgggaGgggatcatAccctatgtttggaaaaTccaaactacgcacagaagttccagggcagagtcacgataaccgcggacaagtccacgaacacagcctacttggagctgagcagcctgagatctgaggacacggccgtgtattactgtgcgagagaagttagtggctacgatttaacagtcgcggggtggtggggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1790 JY8QFUQ01BW0AI No results +1791 JY8QFUQ01B3BDQ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 670 78.7 170/216 nt 78.24 169/216 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found Low V-REGION identity (78,70% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +1792 JY8QFUQ01DJTPF productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1793 JY8QFUQ01A7FYC No results +1794 JY8QFUQ01C0WGL No results +1795 JY8QFUQ01CTYO2 unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F (see comment) 373 64.56 133/206 nt 64.08 132/206 nt 8 7 X 8.7.X [1.17.34.X] null - No rearrangement found Low V-REGION identity (64,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift) cgtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1796 JY8QFUQ01DPDG7 No results +1797 JY8QFUQ01BBPY9 unproductive (see comment) Homsap IGHV3-7*01 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKGGW*R##LDYW out-of-frame - stop codons in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); acctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1798 JY8QFUQ01CGCZI No results +1799 JY8QFUQ01B2VBD No results +1800 JY8QFUQ01AV9ZT No results +1801 JY8QFUQ01AT1TK unknown (see comment) Homsap IGHV1-2*01 F, or Homsap IGHV1-2*02 F or Homsap IGHV1-2*04 F or Homsap IGHV1-2*05 F or Homsap IGHV1-46*01 F or Homsap IGHV1-46*03 F (see comment) 254 69.64 78/112 nt 8 8 X 8.8.X [0.17.4.X] null + No rearrangement found Low V-REGION identity (69,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcaccgaccactatctgcactgggtccgacaggcccctggacaagggcttgagtggatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +1802 JY8QFUQ01BJOJ3 No results +1803 JY8QFUQ01CF40R productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1804 JY8QFUQ01AYVPB No results +1805 JY8QFUQ01CD1QI No results +1806 JY8QFUQ01A302F unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 120 53.9 76/141 nt 10 7 X 10.7.X [1.17.11.X] null - No rearrangement found stop codons tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1807 JY8QFUQ01AFT4R productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 922 92.13 199/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'AG' (2 nucleotides at position 74 to 75 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggctgggagtgggtcAGtctggtataatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +1808 JY8QFUQ01A2D85 No results +1809 JY8QFUQ01BL1DX productive (see comment) Homsap IGHV3-9*01 F 796 85.65 185/216 nt 84.26 182/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [2.16.37.11] CVKDMVAGQGLLSRFDHW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 67 of V-REGION: 3 nucleotides (from position 111 in the user submitted sequence), (do not cause frameshift) agcctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaaggcctggagtgggtcgcgggcatcaactggaatcgggCaaagcattgtatgggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1810 JY8QFUQ01BBZV8 No results +1811 JY8QFUQ01B9QST No results +1812 JY8QFUQ01DPAXM No results +1813 JY8QFUQ01C1QLG unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 863 89.3 192/215 nt 88.84 191/215 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaggggcgtggagtggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +1814 JY8QFUQ01AZD08 productive Homsap IGHV3-30-3*01 F, or Homsap IGHV3-30-3*02 F (see comment) 411 80.0 104/130 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 X 5 18 X.5.18 [X.X.38.11] CARDDFYSSGNYGGFGMDVW in-frame + Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtcactatgactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctcgacagcacccccaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +1815 JY8QFUQ01DQUG3 No results +1816 JY8QFUQ01CGARJ No results +1817 JY8QFUQ01C1OTY unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P 173 59.23 77/130 nt 8 6 X 8.6.X [1.17.11.X] null - No rearrangement found stop codons ctctggattcatcttcagtgactactacatgacctggatccgccaggctccaaggtcttcccgctgagcctcgacaacaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccca +1818 JY8QFUQ01B5IEN No results +1819 JY8QFUQ01DPAHM productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 718 82.16 175/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDWGGSFDRYYFDYW in-frame + Low V-REGION identity (82,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release caccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccaggctcttccccca +1820 JY8QFUQ01BITXO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 779 84.4 184/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1821 JY8QFUQ01BYKOU No results +1822 JY8QFUQ01ASKRO No results +1823 JY8QFUQ01C2X9R No results +1824 JY8QFUQ01CSYUI No results +1825 JY8QFUQ01AEH3Q No results +1826 JY8QFUQ01AR6WE No results +1827 JY8QFUQ01AF8BR No results +1828 JY8QFUQ01DGHZL No results +1829 JY8QFUQ01A30EO No results +1830 JY8QFUQ01COJ91 unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +1831 JY8QFUQ01BIXDD No results +1832 JY8QFUQ01C6E9M No results +1833 JY8QFUQ01CJJV5 No results +1834 JY8QFUQ01A8YRJ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 782 85.12 183/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 8 13 8.8.13 [0.17.38.11] CATYGRFSFSPLDYW in-frame + ctggattcgacttcagtagttatggcttccattgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctaagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctccccttgactactggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1835 JY8QFUQ01DEBHG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + tctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +1836 JY8QFUQ01DGJ7B No results +1837 JY8QFUQ01BPNLJ No results +1838 JY8QFUQ01CE6TX No results +1839 JY8QFUQ01BZB27 No results +1840 JY8QFUQ01DSD1J No results +1841 JY8QFUQ01A9CF3 No results +1842 JY8QFUQ01BJXL8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); ctctggattcacCctttaacaactacgccatgtcctgggtccgccaggctccagggaAaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1843 JY8QFUQ01BOVNW No results +1844 JY8QFUQ01CS04S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1845 JY8QFUQ01C6JP8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1846 JY8QFUQ01DHBAE unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 747 82.49 179/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +1847 JY8QFUQ01DJQS6 productive (see comment) Homsap IGHV3-72*01 F 884 89.14 197/221 nt 88.69 196/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 10 9 8.10.9 [0.17.38.11] CAVAGPPYDGW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); ctggattcaccttaagtgacttctacatggGactggctccgccaggctccagggaaggggctggagtgggttggtcgcagtagaaacaaagctaatggttacagtacacaattcgccgcatctgtgatgggcagattcaccatctcaagagatgactcaaagaatttactatatctacaaatgagcagcctgaaaaccgaggacacggccatttattactgtgctgtcgcaggccccccttatgacggctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1848 JY8QFUQ01ASZ4D No results +1849 JY8QFUQ01DV61W No results +1850 JY8QFUQ01AZTRZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +1851 JY8QFUQ01BMEV3 No results +1852 JY8QFUQ01DBVHS No results +1853 JY8QFUQ01AS5AX No results +1854 JY8QFUQ01AP1CY unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.16.38.11] CVSDLAGQKGF# out-of-frame + in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaagggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1855 JY8QFUQ01CY3DA No results +1856 JY8QFUQ01AKAUZ No results +1857 JY8QFUQ01DV9ZH No results +1858 JY8QFUQ01BQI0I No results +1859 JY8QFUQ01CRM8S unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 684 79.72 173/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (79,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag +1860 JY8QFUQ01B5RFY No results +1861 JY8QFUQ01AVBNZ No results +1862 JY8QFUQ01A1HYP No results +1863 JY8QFUQ01DATML unknown (see comment) Homsap IGHV4-30-2*01 F, or Homsap IGHV4-30-2*02 F or Homsap IGHV4-30-2*03 F or Homsap IGHV4-30-2*05 F or Homsap IGHV4-30-2*06 F 103 70.45 31/44 nt 68.18 30/44 nt X X X X.X.X [14.X.X.X] null + No rearrangement found stop codons in FR1-IMGT, from codon 7 of V-REGION: 6 nucleotides (from position 126 in the user submitted sequence), (do not cause frameshift) ggggaagaagccctggaccaggcatgcgacgaccacgttcccatcttgggggtgctgtcgaggctcagcgggaagaccttggggctggtcggggatgctggggctggcggatgcagttccaggagtaaccactgaaggacccaccacagac +1864 JY8QFUQ01B2MWG No results +1865 JY8QFUQ01DR09H unknown (see comment) Homsap IGHV4-61*02 F 865 88.58 194/219 nt 87.67 192/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 9 7 X 9.7.X [1.17.37.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 27 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 117 in the user submitted sequence), (cause frameshift) tctctggtggctccgtcagtagtggttttactactggagctggacccggcagcccgccgggaagggactggagtggattgggcgtgtccatagcggtggtagttccgactacaaccctccctcacgggtcgagtcaccatcttagtggactcctccaagaatcagttctccctgaggctgacctctgtgacggccgcagacgcggccgtgtatttctgtgcgagagaagcgcctgcctggtccagggcttcttccccca +1866 JY8QFUQ01CLYWH No results +1867 JY8QFUQ01BBW0Y No results +1868 JY8QFUQ01C97D9 No results +1869 JY8QFUQ01BHCHY unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 476 94.34 100/106 nt 8 8 X 8.8.X [1.17.1.X] null + No rearrangement found tctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatact +1870 JY8QFUQ01BJSGI No results +1871 JY8QFUQ01COQXJ No results +1872 JY8QFUQ01AT5DJ unknown (see comment) Homsap IGHV4-4*07 F, or Homsap IGHV4-61*02 F 657 87.13 149/171 nt 8 7 X 8.7.X [1.17.23.X] null + No rearrangement found tatctggtggttcgatcgtcagttactactggagttggatccggcagtccgccgggaagggactggagtggattgggcgcatctactccaatggagatacgaactacaatccctccctcaagggtcgagtcaccatgtcagtagacccttccaacaaccagttctccctga +1873 JY8QFUQ01ACPKI No results +1874 JY8QFUQ01AJ2E8 No results +1875 JY8QFUQ01AZW0U No results +1876 JY8QFUQ01CYDQN unproductive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 X 9.7.X [1.17.38.11] CARGETDC##YYFDYW out-of-frame + stop codons tctctggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaactgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +1877 JY8QFUQ01A3GDX No results +1878 JY8QFUQ01BFJNO No results +1879 JY8QFUQ01ABNRN No results +1880 JY8QFUQ01A72XQ productive Homsap IGHV3-11*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame + cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +1881 JY8QFUQ01CY7BO No results +1882 JY8QFUQ01DH3ZN No results +1883 JY8QFUQ01CFKHZ unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPLGVG#FDNW out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1884 JY8QFUQ01A11WE No results +1885 JY8QFUQ01C5HZ1 productive (see comment) Homsap IGHV4-61*05 F (see comment) 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARDQRGRFGTSSTFDYW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (8 AA in JY8QFUQ01C5HZ1 ; 10 AA in Homsap_IGHV4-61*05) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 89 to 94 in the user submitted sequence), (do not cause frameshift); ctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccgtccctcaagagtcgagtcaccatatcactcgacaagtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacgcggccgtctattactgtgcgagagatcagcggggccgatttggcacctcgtcaacctttgactactggggccagggagcccaggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +1886 JY8QFUQ01AROJ8 No results +1887 JY8QFUQ01DVTFY productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 188 78.69 48/61 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CAREGGRGYDMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtatctatgccatgacctgggtccgccaggctccagggaaggggctggagtggatttcatttatcactgataggggtagtacccaatactacgcagactctgtgaagggccgattcaccgtctccagggaccaagccaagaactcactgtatctacaaatgaacaacctgggagtcgaggacacggctgtgtattattgtgcgagagaggggggacgtggctacgatatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1888 JY8QFUQ01B82PT No results +1889 JY8QFUQ01C8OKU unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 107 53.38 71/133 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +1890 JY8QFUQ01C0DF1 No results +1891 JY8QFUQ01CS4AR No results +1892 JY8QFUQ01DC442 No results +1893 JY8QFUQ01A1LA4 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 94 52.24 70/134 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1894 JY8QFUQ01BIHQJ No results +1895 JY8QFUQ01BLL9W No results +1896 JY8QFUQ01ARX0K No results +1897 JY8QFUQ01B7MV6 productive Homsap IGHV1-24*01 F 970 95.31 203/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame + cggaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +1898 JY8QFUQ01ADVDL unproductive Homsap IGHV1-2*02 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [0.17.38.11] CARDGISMTLVRGVRPFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); tggatacaccttcatcggccattatatacattgggtgcgacaggcccctggacaagggcttgaatgggtAggggtggatcaaccctaacagtggtgttacaaactatgcacagcagtttcaggacagggtcaccatgaccgtcgacacgtccatcagcactgcctacatggacctcaaaagtctaaagtctgacgacacggccatctattactgtgcgagagacggaataagtatgactctggttcggggagttaggcccttcgactactggggccagggaacccctggtcagcgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagccctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1899 JY8QFUQ01C9OGI unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ4*03 F (see comment) 19 63.64 7/11 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. gtctggattcaccttcagtacctatggcacacattgggtccgccaggctccaggcaaggggctggactgggtggcagttagttggcatgatggaagtcaggaatattatgcagactccgtgaggggccgattcactgtctccagagacaattccaagaacacggcatatctgcatatgaatgtcctgagaggcgaagacacggctgtctactactgtgtgagagcggcggggtactgtcctgcctggtccagggcttcttcccc +1900 JY8QFUQ01CJTD8 No results +1901 JY8QFUQ01CC49B productive Homsap IGHV3-48*01 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggatttaccttcagttcttatagtgtcaactgggtccgccaggctccagggaagggcctggagtgggtctcatatattgataatagtggttctaccatatattatgcagactctgtgaagggccgattcaccatctccagagacaatgcccagaactcactgtttctgcaaatgaacagcctgcgagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1902 JY8QFUQ01BJH2P productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccacaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +1903 JY8QFUQ01APY8H No results +1904 JY8QFUQ01B2IGB unproductive Homsap IGHV3-66*02 F 916 92.49 197/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CSTPTYCRGGSCSQ#FDYW out-of-frame + tctggattcaccgtcagtaactaccacatgaggtgggtccgccaggctccagggaaggggctggagtgggtctcagttatttacagcggtggtagtacatattacatagactccgtgaagggccgattcaccatctcgagagacgattccgagaacacagtgtatcttcaaatgaagagcctgagagctgaggacacggctgtatattactgttcgacgcccacatattgtaggggcggtagctgttcccagattttgactattggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +1905 JY8QFUQ01B31PX No results +1906 JY8QFUQ01B0KRM unproductive Homsap IGHV3-33*03 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 X 8.7.X [1.17.38.11] CARDGEQWLVWTL#DVW out-of-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1907 JY8QFUQ01CWAWI No results +1908 JY8QFUQ01CJ7TJ No results +1909 JY8QFUQ01DJ6T7 No results +1910 JY8QFUQ01DWSAC productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'CT' (2 nucleotides at position 24 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagcaacCTgactggatgcactgggtccgccaagctccagggaaggggctggGtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +1911 JY8QFUQ01B9JJ8 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + tctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1912 JY8QFUQ01C5R9N unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 697 80.09 173/216 nt 79.63 172/216 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found stop codons Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactatttcccctgaaccggtgacggtgtcgtggaactca +1913 JY8QFUQ01CPPSP unknown (see comment) Homsap IGHV5-10-1*03 F 82 63.83 30/47 nt 61.7 29/47 nt X X X X.X.X [15.X.X.X] null + No rearrangement found in FR1-IMGT, from codon 9 of V-REGION: 2 nucleotides (from position 130 in the user submitted sequence), (cause frameshift) ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggcaaggaccgatgggcccgttcggtggaggtgacgaagccaccagaga +1914 JY8QFUQ01BRFWK No results +1915 JY8QFUQ01AV6NY No results +1916 JY8QFUQ01B3BE0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 809 86.51 186/215 nt 85.12 183/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 14 8.8.14 [1.16.38.11] CATRNKMGISTPVDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctggactcaacattggcaactatgacatgacctgggtccgccaggctcctgggaagggctggagtgggtctcAagatattggaactactgagggtagctcatattatgcGagactccgtgaagggccggttcaccatctccagagacaactcccagactacgctgtttttggagatgagcagcctgagagacgaggacacggccgtatattactgtgcgacaaggaataaaatgggaattagtacgcctgttgactactggggccagggaaccctagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1917 JY8QFUQ01AWJKI No results +1918 JY8QFUQ01CMR9A unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 94 52.24 70/134 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1919 JY8QFUQ01B6DU1 No results +1920 JY8QFUQ01BCEL1 unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 81 64.44 29/45 nt X X X X.X.X [15.X.X.X] null + No rearrangement found tgggggaagaagccctggaccaggcatgcgacgaccacgttccatcttgggggtgctggtcgaggctcagcgggaagaccttggggctggtcggggatggcatagg +1921 JY8QFUQ01BHCHA No results +1922 JY8QFUQ01BO45P unknown (see comment) Homsap IGHV3-23*05 F 130 52.51 94/179 nt 8 6 X 8.6.X [1.17.27.X] null - No rearrangement found tctggattcccctttagcaactatgccatgacctgggtccgccaggctccaggggagggactggaatgcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1923 JY8QFUQ01A8H23 No results +1924 JY8QFUQ01BSOUI No results +1925 JY8QFUQ01DC38A No results +1926 JY8QFUQ01BZ15F No results +1927 JY8QFUQ01BDX2I unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*05 F or Homsap IGHV3-30*13 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 141 84.62 33/39 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found cctctggattcagcctcacttcctatggcatgaactggg +1928 JY8QFUQ01CLR24 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 998 96.28 207/215 nt 95.35 205/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.16.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1929 JY8QFUQ01CXNVM No results +1930 JY8QFUQ01DG57V No results +1931 JY8QFUQ01B5M1X No results +1932 JY8QFUQ01AP4KF productive (see comment) Homsap IGHV3-9*01 F 986 94.95 207/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [2.16.38.11] CAKSGTYSSSSGHFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gcctctggattcaactttaataaGttatgccatgcactggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1933 JY8QFUQ01A32DB No results +1934 JY8QFUQ01BKBQ4 unproductive Homsap IGHV1-18*01 F 880 90.61 193/213 nt 90.14 192/213 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD1-1*01 F 2 8 7 X 8.7.X [0.17.38.11] CARVIRTNWL#PL out-of-frame + in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) tggttacacctttactacctatggcgtcacctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggtaatacaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacagccgtatattattgtgcgcgagtgattcggaccaactggctcgacccctgggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +1935 JY8QFUQ01DFGBA No results +1936 JY8QFUQ01DPJVA No results +1937 JY8QFUQ01A6727 No results +1938 JY8QFUQ01DII0D unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 799 86.38 184/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 7 X 8.7.X [1.17.38.11] CATLRGV#FDYW out-of-frame + tctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagaggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggctgacggtgtcgtggaactcag +1939 JY8QFUQ01A6BFE unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 3 10 7 X 10.7.X [1.17.38.11] CARHSRLVRYLNS# out-of-frame - in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggaTttgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtacttgaattctgggccagggagccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +1940 JY8QFUQ01CIUY9 No results +1941 JY8QFUQ01BK841 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 913 91.67 198/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + tctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1942 JY8QFUQ01BRJJ1 unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt 97.33 219/225 nt 10 9 X 10.9.X [1.17.38.X] null + No rearrangement found in FR3-IMGT at codon 74 of V-REGION: 'T' (1 nucleotides at position 134 to 134 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaaTgtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcgggggagatatga +1943 JY8QFUQ01A6ZJF unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 387 76.3 103/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (76,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +1944 JY8QFUQ01B76V5 No results +1945 JY8QFUQ01DP6RJ No results +1946 JY8QFUQ01BTUJ4 No results +1947 JY8QFUQ01B3HMS No results +1948 JY8QFUQ01C1W9I No results +1949 JY8QFUQ01DFAVE No results +1950 JY8QFUQ01DFETT No results +1951 JY8QFUQ01BAB6B unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 704 81.6 173/212 nt 81.13 172/212 nt Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD1-7*01 F 1 8 7 X 8.7.X [1.17.37.11] CARLDGHFDL## out-of-frame + Low V-REGION identity (81,60% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 129 in the user submitted sequence), (cause frameshift) tctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggcccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +1952 JY8QFUQ01DVKOS productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARPGVGASSFIDFW in-frame + ttctggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +1953 JY8QFUQ01B74TN unproductive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F (see comment) 408 65.12 140/215 nt 64.65 139/215 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt Homsap IGHD7-27*01 F 3 8 8 2 8.8.2 [1.16.38.6] NR*R in-frame + stop codons Low V-REGION identity (65,12% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctggatttacttttaacaacnattggatgacctgggttcgccaggctccagggaagggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1954 JY8QFUQ01ARCKY No results +1955 JY8QFUQ01C6D1R No results +1956 JY8QFUQ01BJTWV productive (see comment) Homsap IGHV3-13*01 F 961 94.84 202/213 nt 94.37 201/213 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.37.11] CARGSSKAYNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 191 in the user submitted sequence), (cause frameshift) ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccgggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +1957 JY8QFUQ01CQ4P5 No results +1958 JY8QFUQ01CNW3U No results +1959 JY8QFUQ01CZ8KK No results +1960 JY8QFUQ01DSK5G productive (see comment) Homsap IGHV4-39*02 F 853 87.39 194/222 nt 86.04 191/222 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [2.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); gtctctggtgaccccatcggcaacagCtgcttactcctggggctggatccgccagTcccccagggaaTggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1961 JY8QFUQ01DM9PX productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1962 JY8QFUQ01CS3SE No results +1963 JY8QFUQ01ARKFZ productive Homsap IGHV3-9*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + ctctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcc +1964 JY8QFUQ01A1QF8 productive (see comment) Homsap IGHV3-9*01 F 792 85.25 185/217 nt 84.79 184/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); ctctggattcGacctttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +1965 JY8QFUQ01A57Q0 No results +1966 JY8QFUQ01DGXW2 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 1 8 7 X 8.7.X [1.17.38.11] CARADNYDSLGLKFDP# out-of-frame + tctctggtgactccatcagtagtaactactggaactggatccggcagcccccagggaagggactggagtggattgggtatatctatcacagtgggagcaccagctacaacccctccctcaggagtcgagtcaccatatcattagacacgtccaagaaccagttctccctgaaactgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggcggataattatgatagtcttgggctgaagttcgacccctgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +1967 JY8QFUQ01DUGCM No results +1968 JY8QFUQ01CW1IT No results +1969 JY8QFUQ01DVF0A unknown (see comment) Homsap IGHV3-7*01 F 900 90.78 197/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgagcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactcag +1970 JY8QFUQ01BTR5S No results +1971 JY8QFUQ01BCRE0 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 868 89.35 193/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame + tctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc +1972 JY8QFUQ01B23X3 No results +1973 JY8QFUQ01AT12O No results +1974 JY8QFUQ01C8M0Q productive Homsap IGHV3-NL1*01 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 8 12 8.8.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame - ctctggattcacctttagtaactatgacatgggctgggtccgccaggctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +1975 JY8QFUQ01DNNNP unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 700 91.02 152/167 nt 8 7 X 8.7.X [1.17.22.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DNNNP ; 8 AA in Homsap_IGHV3-11*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatct +1976 JY8QFUQ01A62HZ productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 934 93.43 199/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CATAPPGPSYSLEYW in-frame + tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttatgtttagcggtggtggcacaaactacgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacactgtatcttcaaatgaacagcctgagagccgcggacacggccgtgtattactgtgcgaccgccccaccggggccttcttactcgcttgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +1977 JY8QFUQ01BDAGX unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 387 76.3 103/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (76,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +1978 JY8QFUQ01CDNAA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 489 82.98 117/141 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (82,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag +1979 JY8QFUQ01BGV6Q No results +1980 JY8QFUQ01A35OA No results +1981 JY8QFUQ01ALQ2E No results +1982 JY8QFUQ01B1D65 No results +1983 JY8QFUQ01BWP2N No results +1984 JY8QFUQ01ASV3A No results +1985 JY8QFUQ01AG4US No results +1986 JY8QFUQ01BS3RQ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 114 66.67 38/57 nt 8 X X 8.X.X [1.9.X.X] null + No rearrangement found ctctggattcacctttagtaaccattggatggactgggtccagggcttcttccccca +1987 JY8QFUQ01BDQD1 unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + in FR2-IMGT at codon 50 of V-REGION: 'TG' (2 nucleotides at position 64 to 65 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggcgTGgaggtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +1988 JY8QFUQ01DM0QX No results +1989 JY8QFUQ01BQABP No results +1990 JY8QFUQ01BWBEV No results +1991 JY8QFUQ01B6DV5 No results +1992 JY8QFUQ01CBD3F No results +1993 JY8QFUQ01CTQN9 productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARELGGSGTCGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccaggcactatatgcactgggtgcgacaggCcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggggcagagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +1994 JY8QFUQ01CQIDJ No results +1995 JY8QFUQ01CI73V No results +1996 JY8QFUQ01AXXVL No results +1997 JY8QFUQ01DOTOU productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKDHSSGWYYYYGMDVW in-frame + gtctggattcaccttcagtagctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcatttatacggtatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgaaagatcatagcagtggctggtactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagggagtgcatccgccccaaccct +1998 JY8QFUQ01BLQOD No results +1999 JY8QFUQ01DUO6I No results +2000 JY8QFUQ01BH4OY productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F (see comment) 794 84.62 187/221 nt 84.16 186/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 9 15 8.9.15 [1.17.38.11] CTTDSFHIAVHGVFDFW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) tctgcattcatgttcaacaaagcctggatgaattgggtccgccaggctccaggaaagggactggagtgggttggccgtattaaagtaacggcgacggtgcgacagtcgactacgctgcacccgtgaaaggccgattcaccatctcaagagatgattcacagaataccctcttcttacaaatgagcagcctgaaagccgaggacacagccgtctattattgtaccacagatagcttccatattgcagtgcatggcgtctttgacttctggggccagggagccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt +2001 JY8QFUQ01BNCV6 productive Homsap IGHV3-30-3*01 F, or Homsap IGHV3-30-3*02 F (see comment) 411 80.0 104/130 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 X 5 18 X.5.18 [X.X.38.11] CARDDFYSSGNYGGFGMDVW in-frame - Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtcactatgactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2002 JY8QFUQ01A2RVR No results +2003 JY8QFUQ01BG8MK No results +2004 JY8QFUQ01AI06K productive (see comment) Homsap IGHV3-30*01 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ4*03 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 2 8 8 11 8.8.11 [1.16.38.11] CAREWAASHFDHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift) cgctggattcaccttcagtggctttgcttgcactggctccgccaggctccagacaaggggctagagtgggtgggatttacatcatttgatgggagtaacagagactacgcagactccgtgaagggccgattcacgatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagacctgacgacacggctgtatattactgtgcgagagagtgggcagccagtcactttgaccactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2005 JY8QFUQ01DDZUD unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*03 F 810 86.18 187/217 nt Homsap IGHJ6*02 F (see comment) 157 72.58 45/62 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDQRDYDYIYYY#GMDLW out-of-frame + Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) ctctggattctccctcaggaatcatgctatgcactgggtccgccagactccaggcaagggactcgagtgggtggcagttatctcatttaatggacgaaggaagtattatgcagacttcgtgaagggccgattcaccatcaccagggacaattcccagaacactctgtctctgcaattgaatagcctgggaactgaggacacggctgtctattactgtgcgagagatcagcgtgactacgattacatctactattacggggatggacctctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +2006 JY8QFUQ01A3LWV unproductive (see comment) Homsap IGHV4-59*02 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-2*01 F 3 8 7 X 8.7.X [1.17.38.11] CARPVLF*YQLLV#FDYW out-of-frame + stop codons ctctggtggccccggcagtagttaggactggacctggatccggcagcccccagggaagggactggagtggattggatatatttattacagtgggagcaccaactacaaccccttcctcaagagtcgagtcaccatatcagtagacacgtccaagaacttgttctccttgaggctgagctctgtgaccgctgcggacacggccatatattactgtgcgagacccgtattgttttagtaccagctgttagtcactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2007 JY8QFUQ01AYO4H No results +2008 JY8QFUQ01CU4N0 No results +2009 JY8QFUQ01CO7MH No results +2010 JY8QFUQ01BKBUH No results +2011 JY8QFUQ01DJWN9 unproductive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 777 85.05 182/214 nt 83.64 179/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*01 F 2 8 8 X 8.8.X [0.17.38.11] CARGILR##HFDSW out-of-frame - stop codons in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'T' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); tggatacaccttcagcgactactacatacactggctgcgacagGgcccctggacaacgacttgagtggatgggatggctGgaaccctaaTaaatggtgacacagcttatggccagagcttcaagggccgggtcaccatgaccagggacacgtccgtcagcacagtgtacgtggaggtgaggaggctgagatctgacgacacagccctttatttctgtgcgagaggcattttacggtgaccactttgactcctggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2012 JY8QFUQ01BJ0J7 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 84.62 187/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); tctctggtgactcCcatcagtagtactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2013 JY8QFUQ01DT1ZM productive (see comment) Homsap IGHV3-33*03 F 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 7 8 13 7.8.13 [1.17.38.11] CARSDLSMVRDLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift) cgtctggattcacctcagtacctatggcatgcactgggtccgccaggctccaggcaaggGggctggagtgggtggcaatgatttggtatgatggaagccttacatattatgaagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgctgtttctgcaaatgaatagcctgagagtcgaggacacggctctgtattactgtgcgagatccgacctctctatggttagagatcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2014 JY8QFUQ01DG8YX No results +2015 JY8QFUQ01CI1V6 No results +2016 JY8QFUQ01AYX4Y productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2017 JY8QFUQ01B68YS productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARPLRATYGDYVNW in-frame + ctctggattcaccttcgataactatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcaaaggatggaagtattgaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacaatttatctgcaaatgaacattgtgagggttgaggacacggctatgtattactgtgcgagaccccttcgggcaacttacggtgactacgtgaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2018 JY8QFUQ01A2G8U productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 709 81.69 174/213 nt 81.22 173/213 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.37.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 130 in the user submitted sequence), (cause frameshift) ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2019 JY8QFUQ01DK569 No results +2020 JY8QFUQ01DXFTY No results +2021 JY8QFUQ01A1YTY No results +2022 JY8QFUQ01B6HFK No results +2023 JY8QFUQ01DUD3U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcacttttaggagtcatatgatgagttgggtccgccagactccagggaaggggctggaatgggtctcaagtattcgagccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaactccaagaacacgatgtatttgcaaatgcacagcctgagagtcgacgacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggcccagggagccctggtctccgtctgcctcagcatccccgaccagccccaaggtcttcccgctgaccctcgncagcaccccccaagatgggaacgtggtcgtcgcatgccctggtccaggggcttcttccccca +2024 JY8QFUQ01DEMJX productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 1029 98.13 210/214 nt 97.2 208/214 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-2*02 F 2 8 7 15 8.7.15 [1.17.38.11] CARGVGVSWHTEYFQHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); ctctgggttcaccgtcagtagcGaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttaCtttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagaggggtcggcgtcagctggcatactgaatacttccagcactggggccagggcaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2025 JY8QFUQ01ACURH productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 7 12 8.7.12 [1.17.38.11] CARAPGWMNPFDFW in-frame + tctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +2026 JY8QFUQ01CTXHU unknown (see comment) Homsap IGHV3-11*03 F, or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F 89 51.88 69/133 nt 8 10 X 8.10.X [2.17.9.X] null - No rearrangement found stop codons agcctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2027 JY8QFUQ01C3TXW No results +2028 JY8QFUQ01B7828 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 401 77.21 105/136 nt 76.47 104/136 nt 8 8 X 8.8.X [1.16.11.X] null - No rearrangement found Low V-REGION identity (77,21% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccgggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +2029 JY8QFUQ01CTQ8T No results +2030 JY8QFUQ01BZ8E5 No results +2031 JY8QFUQ01DS2MQ productive (see comment) Homsap IGHV3-48*03 F 796 85.65 185/216 nt 85.19 184/216 nt Homsap IGHJ6*02 F (see comment) 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 7 8 14 7.8.14 [1.17.38.11] CVRQTGDYYFFGLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) ctctggattcgccttcaaaagtttaacatgaattgggtccgccaggcttcagggaaggggccggagtggattgcatacattaatggaagagggactaacatctactatgcagactctgtgaagggccggttcaccatctccagagacaacgcccagaacgcagtgcatctgcagatggaccgcctgagagtcgaggacacggccctatattactgtgtgagacaaactggagactactatttcttcggtctggacgtctggggccaaggaaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2032 JY8QFUQ01DLJDT No results +2033 JY8QFUQ01AX4GW No results +2034 JY8QFUQ01CHGVS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 594 75.12 163/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGRSWNHEVEYW in-frame + Low V-REGION identity (75,12% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacacttaggaattatgatatgaactggatccgccaggctccggggaaggggctagagtgggtctcaagtcttagacttgggtcctatgacacaaattatgcagagtctgtagcgggccggttcgtcgtctccaaagacgaggccagaaacacaatgtttctcctgatgaacgacctgcgagtcgaggacacggccttatattactgtgcgggaaggagttggaatcatgaagttgaatactggggccagggaaccctggtcaccgtctcttcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2035 JY8QFUQ01A6EXK No results +2036 JY8QFUQ01CFUGF No results +2037 JY8QFUQ01BZC7E No results +2038 JY8QFUQ01DSOJF unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 684 94.12 144/153 nt 8 8 X 8.8.X [1.17.16.X] null - No rearrangement found cctctggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaacg +2039 JY8QFUQ01DS062 No results +2040 JY8QFUQ01BXYLF productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaatcctggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctcgacaacacccccaagtggtcgtcgcatgcctggtccagggcttcttccccca +2041 JY8QFUQ01DR5PE No results +2042 JY8QFUQ01A9S9F No results +2043 JY8QFUQ01AENCQ unproductive (see comment) Homsap IGHV3-48*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKCQDLFLWFGELFP#FDYW out-of-frame + stop codons ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcaaaatgccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +2044 JY8QFUQ01DFZH3 No results +2045 JY8QFUQ01DMKZ0 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 118 67.86 38/56 nt 8 X X 8.X.X [1.9.X.X] null + No rearrangement found tctggattcacctttagtaaccattggatgaactgggtccagggcttcttccccca +2046 JY8QFUQ01BFRM4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame - tctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagatagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2047 JY8QFUQ01BRNVT No results +2048 JY8QFUQ01AYNGJ productive Homsap IGHV3-NL1*01 F (see comment) 393 78.46 102/130 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 X 5 11 X.5.11 [X.X.38.11] CACGHMRDGYDVW in-frame + Low V-REGION identity (78,46% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcatcagttatgactccgtgaagggccggttcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2049 JY8QFUQ01BPXE5 unknown (see comment) Homsap IGHV3-21*04 F (see comment) 733 81.94 177/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (81,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcaccttcagtagctatagcatgatctgggtccgccaggctccagggaaggggctggagtgggtctcatccattaggagtagttgtacttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2050 JY8QFUQ01BOIQS No results +2051 JY8QFUQ01CE71S No results +2052 JY8QFUQ01AYKXY No results +2053 JY8QFUQ01AKKUX productive (see comment) Homsap IGHV3-7*01 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.37.11] CASGSGWTAEYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 103 in the user submitted sequence), (cause frameshift) tctgaattcaccgttagcagtcattggatgaattgggtccgccaggctccagggaaggggctggaatgggtggccaacataaaacaagatgcaagtgagaaaactatgtggactctgtgaagggccgattcaccatctcccgagacaacgccaagaattcactgtatctgcaaatgaacagcctgagactcgaggacacggctgtgtatttctgtgcgagtggcagtggctggacagctgaatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +2054 JY8QFUQ01ADWFW No results +2055 JY8QFUQ01A4G76 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 871 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 6 16 8.6.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 83 in the user submitted sequence), (cause frameshift) cctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttattatagcaatggtgaaacaatctacgcagactccntgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2056 JY8QFUQ01CD1T0 unknown (see comment) Homsap IGHV3-74*03 F 119 54.62 71/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +2057 JY8QFUQ01C6T9J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKGDSGIRPIDYW in-frame + cctctggattcacctctagcgcctataccatgagttgggtccgccaggctccagggaaggggctggagtgcgtctcagctattagtggtggtggtactagcacatactacgcagactccgtgaagggccggttcaccatctccagagacacttccaagaacacactgtctctgcacctgaacagcctgagagtcgaggacacggccatatatttctgtgcgaaaggtgattctggtataagacctattgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +2058 JY8QFUQ01DRHHV No results +2059 JY8QFUQ01AV72D unproductive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 1080 100.0 217/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGFPWFGEEYYF*LL# out-of-frame + stop codons ctctggattcacctttgatgattatggcatgagctgggtccgccaagctccagggaaggggctggagtgggtctctggtattaattggaatggtggtagcacaggttatgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccttgtatcactgtgcgagaggtttcccatggttcggggaggaatactacttttgactactggggccagggtaaccctggtcaccgtctcctcagggagtgcatccgccccaa +2060 JY8QFUQ01B04MT unproductive Homsap IGHV2-5*02 F, or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F 834 86.82 191/220 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD6-6*01 F 2 10 7 X 10.7.X [1.17.38.11] CAHFGPQEHFDFW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattctcactcagcaccaatggaatgggtgtgggttggatccgccagcccccgggagaggccccagactggctcgctctcatttattgggatgatgataagcgataccggccatccctagagagtagactcaccatcaccaaggacatctccacaaaccaggtggtccttagaatgaccgacatgggccctgcagacacagccacatatttctgtgcacactttggaccacaggagcacttcgacttttgggggtccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2061 JY8QFUQ01B3HZ7 No results +2062 JY8QFUQ01BI0JQ No results +2063 JY8QFUQ01DVXTX No results +2064 JY8QFUQ01BF1N2 No results +2065 JY8QFUQ01AXU4F unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARLGATRS*LL# out-of-frame + stop codons ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttggggcaactcgctcttgactactgggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +2066 JY8QFUQ01AMV8F No results +2067 JY8QFUQ01DVMY3 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2068 JY8QFUQ01C389G No results +2069 JY8QFUQ01BI6HV productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGXYYDSGGLDNW in-frame + tccggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtnattattatgatagtggtggtcttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtctcgcctgcctggtccagggcttcttccccca +2070 JY8QFUQ01AA3TT No results +2071 JY8QFUQ01A9HTT No results +2072 JY8QFUQ01AIVTV No results +2073 JY8QFUQ01DJPKB No results +2074 JY8QFUQ01DOVP6 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 462 70.77 138/195 nt 8 7 X 8.7.X [1.17.32.X] null + No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DOVP6 ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (70,77% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2075 JY8QFUQ01DRQV8 No results +2076 JY8QFUQ01DIRXR No results +2077 JY8QFUQ01COTM3 No results +2078 JY8QFUQ01BLIBB No results +2079 JY8QFUQ01DE488 No results +2080 JY8QFUQ01DXA71 No results +2081 JY8QFUQ01BWJXL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 7 12 8.7.12 [1.17.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2082 JY8QFUQ01C3ER5 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 113 55.08 65/118 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found ctctggattcaccttcagtgactactacatgaactggatccgccaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +2083 JY8QFUQ01CT9PI No results +2084 JY8QFUQ01CZFE8 productive Homsap IGHV3-7*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 8 8 8 8.8.8 [1.17.38.11] CGTSRSLDYW in-frame - ctctggattcacatttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatgggagtgagaaatactatgtcgactctgtgaagggccgattcaccatctccagagacaacgccgagaactcactacatttgcaaatgaacagcctgagagccgaagacacggctgtgtattactgtgggacgagcaggtcccttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2085 JY8QFUQ01CCRB7 unknown (see comment) Homsap IGHV3-7*02 F 109 59.04 49/83 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2086 JY8QFUQ01DIV7A productive (see comment) Homsap IGHV1-18*01 F 966 94.86 203/214 nt 94.39 202/214 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARENYYTSGIHSGFRHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggttacatctttaccacctatggtatcagttgggtgcgacaggCcccctggacaagggcttgagtggatgggatggatcaacacttacaatggtaacacgaactatggacagaggatccagggcagagtcaccatgaccacagacacatccacgagcacagcctacatggagctgaggagcctgagatctgacgacacggccgtatattattgtgcgagagaaaactactatacttcgggaattcattccggcttcaggcactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2087 JY8QFUQ01BQ1MZ No results +2088 JY8QFUQ01DN3N9 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 900 90.78 197/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) ggcctctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2089 JY8QFUQ01C8KTQ No results +2090 JY8QFUQ01AA6NJ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 913 91.67 198/216 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDHGHCNSGVCMNYGLDVW in-frame + Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) tctggattcagcttcagtacttatggcatgcactgggtccgccaggctccaggcaaggggctggaatgggtggcaggcacgtcatctgatggcagtcataaataccaggcagactccgtgaagggccgattcaccatctccagagacaactccgagaacacggtgtatctgcaaatgaacagcctgagagttgaggatacggctgtgtattactgtgcgaaagatcatggacattgtaatagtggagtgtgtatgaactacggtttggacgtctggggccaagggaccacggtcaccgtcttcccagcttccaccaagggcccatccgtcttcccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +2091 JY8QFUQ01DIQ9W No results +2092 JY8QFUQ01A21H5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARPLSGSSRSPSGYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatggtgatgggactagcacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgttgtatttgcaactgagcagtctgagagccgaggacacggctgtgtatttctgtgcaagacccttgagtgggagttccagatcccccagcggctactggggccagggaaccctggtcaccgtctcctccgcatcccgaccagctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcatcgcctgcctggtccagggcttcttccccca +2093 JY8QFUQ01AO7GC No results +2094 JY8QFUQ01BAXIB No results +2095 JY8QFUQ01BLHNK No results +2096 JY8QFUQ01BLH9B productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'TG' (2 nucleotides at position 65 to 66 in the user submitted sequence), (cause frameshift); cctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggcgTGggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccctctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2097 JY8QFUQ01BDUVW No results +2098 JY8QFUQ01CSKOX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDQSCIVGPCGFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2099 JY8QFUQ01CRX44 No results +2100 JY8QFUQ01BXIPW No results +2101 JY8QFUQ01BIYZO No results +2102 JY8QFUQ01CFUT5 unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2103 JY8QFUQ01BCVOY unproductive (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F (see comment) 413 80.8 101/125 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 X 3 X X.3.X [X.X.38.11] CASFAGPVVVTL*WLLVRLT#YCDYR out-of-frame - stop codons Low V-REGION identity (80,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgcattcaccgtcagtaggctccgtgacgggccgagtcatcatctccagagagaatgcccagaactccgtgtatcttccactgaacagcctgagagccgggaacacggctgtgtatcactgcgcaagttttgctggccctgtggtggtgactctatagtggctgttggtccgtctgaccactactgtgactaccggggcctgggaaccccggtccccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2104 JY8QFUQ01AN9S9 No results +2105 JY8QFUQ01CKNXR No results +2106 JY8QFUQ01BFLW8 No results +2107 JY8QFUQ01DGS48 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 779 83.94 183/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtggaactcag +2108 JY8QFUQ01DJAK2 No results +2109 JY8QFUQ01ACS0O No results +2110 JY8QFUQ01BVLI5 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2111 JY8QFUQ01A8G4W No results +2112 JY8QFUQ01ASMWW productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcacctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2113 JY8QFUQ01DXHW0 No results +2114 JY8QFUQ01AF1CO No results +2115 JY8QFUQ01BK1E5 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CASFACPGK#GYW out-of-frame + ctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttgcgtgtcctggaaagtggctactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +2116 JY8QFUQ01AEU7T No results +2117 JY8QFUQ01C1U2A No results +2118 JY8QFUQ01C1NGM No results +2119 JY8QFUQ01BHOKR No results +2120 JY8QFUQ01C3O3B No results +2121 JY8QFUQ01BG6XX unproductive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 392 64.22 140/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found Low V-REGION identity (64,22% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. gctacggatttgtcttcagtggcactaatatgaattggctccgccaggctccagggaaggggctggagtggatttcacacattagtcacaatagtgaaaccatattctatgcagactctgtgaggggccgagtcaccatctccagagataaatacaattttgacgactggggccagggaaccctggtcaccgtctcccttgcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2122 JY8QFUQ01DGW16 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - tctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2123 JY8QFUQ01A5QNH No results +2124 JY8QFUQ01BUOZE productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 7 8 14 7.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) tctggattcaccttcaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +2125 JY8QFUQ01DNIB4 No results +2126 JY8QFUQ01DJ168 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.37.11] CARGLAVILGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2127 JY8QFUQ01CVAW1 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggcgtgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2128 JY8QFUQ01CRPAZ productive Homsap IGHV3-48*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDQSPGVAVAGPDYW in-frame + ctctggattcaccttcagtagatatagtatgaactgggtccgccaggctccaggaaaggggctggagtgggttgcatacattagaagtagcagtagtgtcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcaaagtccgggtgtagcagtggctggtcctgattactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaanatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2129 JY8QFUQ01AR7ZE productive (see comment) Homsap IGHV3-7*01 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.37.11] CSRLLEEW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +2130 JY8QFUQ01CWBX3 No results +2131 JY8QFUQ01A38VY No results +2132 JY8QFUQ01A2ZSI No results +2133 JY8QFUQ01B6KUR No results +2134 JY8QFUQ01AL7P8 No results +2135 JY8QFUQ01B5HCF unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.12 203/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2136 JY8QFUQ01C2945 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [2.17.38.11] CARFGPLTRPDY## out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); gcctctggaGttcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaacctttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2137 JY8QFUQ01DJTI7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 915 90.5 200/221 nt 90.05 199/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [2.17.38.11] CIMDLVGRADYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'A' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift); cagccnctggattcaactttaacagctttgccatgagctAgggtccgccaggttccagggatggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactccgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2138 JY8QFUQ01A0EFO unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 700 91.02 152/167 nt 8 7 X 8.7.X [1.17.22.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01A0EFO ; 8 AA in Homsap_IGHV3-11*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatct +2139 JY8QFUQ01AHSGI unproductive Homsap IGHV1-69*02 F 813 86.92 186/214 nt Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [0.17.38.11] CATDHPAGVSP#YW out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tggggccaccttcaacagttatactttcagctgggtgcgacaggcccctggacaagggcttgagtggatgggaatgatcatctccacccttggtgtgacaaactacgcgcagaggttccagggcagagtcacgatctccgcggacaagtccacgacgacagcctacatggagttgacaaggctgacatttgaagacacggccgtttattattgtgcgacagatcatcccgcgggcgtcagtccgtgtactggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2140 JY8QFUQ01BEKEH productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1057 99.07 214/216 nt 98.61 213/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [2.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2141 JY8QFUQ01C2H6O No results +2142 JY8QFUQ01CE5UM productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F (see comment) 347 75.0 96/128 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-16*02 F 3 X 4 11 X.4.11 [X.X.38.11] CARGDLPHYIDYW in-frame + Low V-REGION identity (75,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacatcttcaccagctacttttatgcactggggcagagtcaccatgaccagcgacacgtccacgaccacagtctacatggagctgagcagcctgagatccgacgacacggccatatattactgtgcgagaggcgatctcccccactacattgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +2143 JY8QFUQ01DS048 No results +2144 JY8QFUQ01BP2O3 No results +2145 JY8QFUQ01B8PL6 No results +2146 JY8QFUQ01C6EBM No results +2147 JY8QFUQ01BRDLB productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - ctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2148 JY8QFUQ01CAX4Q productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 828 87.1 189/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARLRSFGDYPLDVW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +2149 JY8QFUQ01DEDQY No results +2150 JY8QFUQ01CYNMU No results +2151 JY8QFUQ01CQRVK productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 976 94.91 205/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.16.38.11] CARGEMTAEYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) ctctggtggctccatcagcagtgttCaactggtggagttgggtccgccagcccccagggaaggggctggagtggattgggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2152 JY8QFUQ01DK0LQ No results +2153 JY8QFUQ01DPXYW No results +2154 JY8QFUQ01BUOSY productive Homsap IGHV4-34*03 F 881 90.19 193/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 228 94.12 48/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CVRNYYDFSGYFNWFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tgtctggtaggtccttcagtggttactactggagttggatccgccagcccccagggaaggggctggagtggattggggaaatcaattatagaggaagtaccaactacaatccgtccctcaaaagtcgagtcaccgtgtcttcagacacgtccaagaatcagttctccctggagttgatctctgtgaccgccgcggacacggccatatattattgtgtgagaaattactatgattttagtggttatttcaattggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2155 JY8QFUQ01AOEAZ No results +2156 JY8QFUQ01CS6F1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt Homsap IGHJ6*02 F 263 94.83 55/58 nt Homsap IGHD1-26*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDYYYYGMDVW in-frame + tctggattcacctttagcaactttgccatgagctgggtccgccaggctccagggaagggactggagtgggtctcgactattagtcctagtggtggtaccacatattacgcagactccgtgaagggccggttcaccatctccagagacagttccaagaacacgctgtatctgcaaatgaacatcctgagagtcgacgacacggccatgtatttctgtgtgagagactactattattacgggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2157 JY8QFUQ01DV5VI No results +2158 JY8QFUQ01CQE4K No results +2159 JY8QFUQ01A5IOF productive Homsap IGHV3-11*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2160 JY8QFUQ01BFIN2 No results +2161 JY8QFUQ01DRC1V No results +2162 JY8QFUQ01AUJFT No results +2163 JY8QFUQ01DSE2Q No results +2164 JY8QFUQ01A2RMY No results +2165 JY8QFUQ01CS41F unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 858 89.25 191/214 nt 88.79 190/214 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD2-21*01 F 2 10 7 X 10.7.X [1.17.37.11] CARGA*YL*Q#PW out-of-frame + stop codons The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01CS41F ; 8 AA in Homsap_IGHV4-59*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 92 of V-REGION: 1 nucleotides (from position 184 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagcggcagtaccaactactggacctggatccggcagcccccaggaaagggactggaattcattgggtatatctataacagtggcaacaccaactacaacccctccctcaagagccgagtctccatttctttggacaggtccaagaaccagttctccctgaggctgaccccgtgaccgctgcggacacggccatgtattactgtgcgaggggggcatgatacctatgacagcccgtggggccagggaacccgggtcaccgtctcctcggcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccctcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2166 JY8QFUQ01ADC3R No results +2167 JY8QFUQ01BBP1D No results +2168 JY8QFUQ01B2S6H No results +2169 JY8QFUQ01BTTXM unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 489 83.1 118/142 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 1 X 7 X X.7.X [X.2.38.11] CVSDLAGQKGS# out-of-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BTTXM ; 8 AA in Homsap_IGHV3-74*01), and low V-REGION identity (83,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcaggattcaccttcagtagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtgggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagcatggaagcgtggtcgtcgcatgcctggtccagggcttcttccccca +2170 JY8QFUQ01ADH67 productive (see comment) Homsap IGHV3-43*01 F, or Homsap IGHV3-9*01 F 332 91.25 73/80 nt 90.0 72/80 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 X 16 8.X.16 [1.3.14.11] CAKDGSAIPVTGTYFEYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 138 nucleotides (from position 39 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttcatgattataccatgcactggatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2171 JY8QFUQ01DS1QC No results +2172 JY8QFUQ01C9X8X unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 96 52.71 68/129 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons tctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +2173 JY8QFUQ01DKV9P No results +2174 JY8QFUQ01CSUWR unknown (see comment) Homsap IGHV3-64*03 F, or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 161 57.89 77/133 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccaaggtcttcccgctgagcctcgacagcaccccccaagatgggcaacgtggtcgtcgcatgcctggtccagggcttcttcccc +2175 JY8QFUQ01CF034 No results +2176 JY8QFUQ01AJGJC No results +2177 JY8QFUQ01CXTYT No results +2178 JY8QFUQ01DKJE8 No results +2179 JY8QFUQ01DUCDS unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F 330 88.24 75/85 nt Homsap IGHJ2*01 F 76 60.38 32/53 nt Homsap IGHD4-17*01 F 3 X X X X.X.X [X.X.28.11] CARLGQLALDY## out-of-frame + caccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggcaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +2180 JY8QFUQ01CQ9CQ No results +2181 JY8QFUQ01CBRRR No results +2182 JY8QFUQ01CBWKF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2183 JY8QFUQ01BXJ7S No results +2184 JY8QFUQ01ATV5U No results +2185 JY8QFUQ01AMCBG No results +2186 JY8QFUQ01ATKWD productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +2187 JY8QFUQ01A5287 No results +2188 JY8QFUQ01BJD14 No results +2189 JY8QFUQ01DSUH3 No results +2190 JY8QFUQ01CVTAB No results +2191 JY8QFUQ01C989A No results +2192 JY8QFUQ01DP1YW No results +2193 JY8QFUQ01AVAVU No results +2194 JY8QFUQ01C7CV2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKDPGNYWGYYYDSW in-frame + ctctggattcacctttagcagttatgccatgagctgggtccgccagactccagggaaggggctggagtggatctcagaaattactggtgatggcgataacatatactacgcagactccgtgaagggccgtttcaccatctccagagacaattccaagaacactctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatccggggaactattgggggtactactatgactcttggggcctgggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2195 JY8QFUQ01CWN4G unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 639 76.96 167/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (76,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2196 JY8QFUQ01A1BZT No results +2197 JY8QFUQ01DN2ZY unproductive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDQVTEDY# out-of-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactgggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2198 JY8QFUQ01CRNHB No results +2199 JY8QFUQ01BOBP5 No results +2200 JY8QFUQ01C2QIG No results +2201 JY8QFUQ01BDLFT No results +2202 JY8QFUQ01CI5VP No results +2203 JY8QFUQ01AW9VS unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRQLGFGDLFRFD#PW out-of-frame + ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgaccccttggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2204 JY8QFUQ01ATYMV productive (see comment) Homsap IGHV3-74*03 F 926 92.56 199/215 nt 92.09 198/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.16.38.11] CAREDGSGRRHFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagccactggatgcactgggtccgccaaggtatagggaggggctggtgtggcttgcacgtattaacagtgatggcagtagtacagcttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaagacgctttatctgcaaatgaacagtctgagagtcgaggacacggctgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2205 JY8QFUQ01C19UU No results +2206 JY8QFUQ01AOAG7 No results +2207 JY8QFUQ01AV9Y3 No results +2208 JY8QFUQ01DMXUS No results +2209 JY8QFUQ01B0KMP productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 947 92.31 204/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARQSFDFAWQWQVDYYFEYW in-frame + tctctggtggctccgtcagcagtagcacttactactggggctggctccgccagtccccagggaaggctctggagtggattgggactatccatcatagtgggagcacctaccagaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaggaaccagttctccctgaggctgagctctgtgaccgccgcagacacggctctttattactgtgcgagacaaagctttgatttcgcgtggcagtggcaggtagattattactttgaatactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +2210 JY8QFUQ01AVWI5 No results +2211 JY8QFUQ01C2RY1 No results +2212 JY8QFUQ01AGGEA productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 696 80.84 173/214 nt 80.37 172/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [1.16.38.11] CARAYTFSLFGVASHWYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tctctgatgggtcgttcatgggttacctctggaattggatccgccagccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2213 JY8QFUQ01BFFQA No results +2214 JY8QFUQ01CZINL No results +2215 JY8QFUQ01C9B9C No results +2216 JY8QFUQ01CSZZY productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 849 88.79 190/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD6-25*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRMAAARDGVDIW in-frame + ctctgggttcgccgtcagtagcaagttcatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatcctgatgggactacacactatggagactccgtgaggggccgattcaccacctccagagacaattctaagaacatcttggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggatggctgcggcgcgtgatggtgttgacatctggggccaaggcacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +2217 JY8QFUQ01B0CWS No results +2218 JY8QFUQ01DBFGV No results +2219 JY8QFUQ01A5RHY No results +2220 JY8QFUQ01BI6AD productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2221 JY8QFUQ01AWM45 productive Homsap IGHV3-7*01 F 904 91.2 197/216 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + tctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +2222 JY8QFUQ01CZHVS productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*07 F 813 85.2 190/223 nt 84.75 189/223 nt Homsap IGHJ5*02 F 110 69.39 34/49 nt Homsap IGHD1-26*01 F 2 8 10 5 8.10.5 [1.17.38.11] CREAIAW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 86 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); ctctgggttcgtgttcggtaacttctttatgaattggttccgccagcctccgggaaaggggctggagtgggttggccgcatcaaaaccaaagttgatggtgagacaacagactacgctgcagccgtgaaagacagattcatcatttcaagagatgattcaaaaaatTacgatgtatctgcaaatgaacgacctgaagaccgaggacacggccgtatattattgtcgggaggccatcgcgtggggccagggaaccctggtcaaggtctcatcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +2223 JY8QFUQ01DHJ1Z productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +2224 JY8QFUQ01BKNX7 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 85 52.0 65/125 nt 8 7 X 8.7.X [1.17.8.X] null - No rearrangement found tctggattcaccttcagtgactactacatgaactggatccgccaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2225 JY8QFUQ01DWYF2 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 184 59.7 80/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +2226 JY8QFUQ01DWVJO unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 888 89.55 197/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD5-18*01 F 3 10 7 X 10.7.X [1.17.38.11] CARHSRLVRYFEF## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactataacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggcccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2227 JY8QFUQ01B0642 No results +2228 JY8QFUQ01A98D6 unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 X 10.9.X [1.17.38.11] CTRGSSRGGDMMRTTMS#DFW out-of-frame + tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcgggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccg +2229 JY8QFUQ01ATAVU No results +2230 JY8QFUQ01BD3Z5 No results +2231 JY8QFUQ01BTO0L productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2232 JY8QFUQ01CF4VF No results +2233 JY8QFUQ01CUWFA unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +2234 JY8QFUQ01BX70E No results +2235 JY8QFUQ01CYQUJ productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 882 89.86 195/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [2.17.38.11] CARPTYSSGRDAFDTW in-frame - tgtatatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaatagtcgagtcatcatatcgatagacacgtccaagaaccaggtctccctgaagctcttctctgtgaccgccgcggacacgggtgtgtactattgtgcgaggcccacgtatagtagcggccgggacgcctttgatacctggggccaagggacgacggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2236 JY8QFUQ01CGN24 No results +2237 JY8QFUQ01DNGB1 No results +2238 JY8QFUQ01CGEHA productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtacttactactggacatGggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2239 JY8QFUQ01B7X9B No results +2240 JY8QFUQ01A8RFP unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 523 93.28 111/119 nt 8 8 X 8.8.X [1.17.5.X] null - No rearrangement found cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatctattggtagtagtagtagtgacatatactacgcagaccca +2241 JY8QFUQ01CUYWA No results +2242 JY8QFUQ01DKXJ4 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 406 89.11 90/101 nt 8 7 X 8.7.X [1.17.X.X] null - No rearrangement found cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagggtgttgaca +2243 JY8QFUQ01BH8AQ unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2244 JY8QFUQ01AQH3D productive (see comment) Homsap IGHV3-7*01 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.37.11] CSRLLEEW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 103 in the user submitted sequence), (cause frameshift) tctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaacgatggaagcgtggtcgtcgcatgccctggtccagggcttcttccccc +2245 JY8QFUQ01DN5JE No results +2246 JY8QFUQ01BB93P unproductive Homsap IGHV3-7*01 F 1027 96.8 212/219 nt 96.35 211/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [2.17.38.11] CAISSGFTRR#YW out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGcctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2247 JY8QFUQ01DW2P7 productive (see comment) Homsap IGHV3-23*05 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggctccagggcttcttccccc +2248 JY8QFUQ01BSP8D unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 425 76.35 113/148 nt 8 7 X 8.7.X [1.17.16.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BSP8D ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (76,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactacttccccgaaccggtgacggtgtcgtggaactca +2249 JY8QFUQ01CAUAC No results +2250 JY8QFUQ01AFWZL No results +2251 JY8QFUQ01BLQKE productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccgtcagcagtggtaattactactggaactggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2252 JY8QFUQ01BS4DR No results +2253 JY8QFUQ01AS7FQ No results +2254 JY8QFUQ01CUTG2 No results +2255 JY8QFUQ01BJKIG No results +2256 JY8QFUQ01DXIMW productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1062 96.9 219/226 nt 96.02 217/226 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'A' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); taccggggacagtgtctctaccaacagagctgcAttggaactggatcaggcagtGccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2257 JY8QFUQ01BUJC8 No results +2258 JY8QFUQ01C57KK No results +2259 JY8QFUQ01A4FOX No results +2260 JY8QFUQ01BQA7E unproductive Homsap IGHV4-61*02 F 883 89.5 196/219 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 10 7 X 10.7.X [1.17.38.11] CARQGDSSGPWNDY## out-of-frame + tccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +2261 JY8QFUQ01ABVZ2 unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 118 58.7 54/92 nt 56.52 52/92 nt 8 X X 8.X.X [21.1.X.X] null - No rearrangement found in FR1-IMGT, from codon 14 of V-REGION: 2 nucleotides (from position 100 in the user submitted sequence), (cause frameshift)in FR1-IMGT, from codon 20 of V-REGION: 10 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) gggggaagaagccctggaccaggcaggcgatgaccacgttcccatctggctgggtgctgcagaggctcagcgggaagaccttggggctggtcggggatgctgggggctggcggatgcagttccaggagtaaccactgaaggacccaccacaga +2262 JY8QFUQ01C1XGN No results +2263 JY8QFUQ01CYFW8 unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF (see comment) 284 69.29 88/127 nt 68.5 87/127 nt 8 8 X 8.8.X [1.16.8.X] null + No rearrangement found Low V-REGION identity (69,29% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaagggctggaatgggtcggtggtgttaattggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2264 JY8QFUQ01CCBHV No results +2265 JY8QFUQ01AU12V No results +2266 JY8QFUQ01AO7RK No results +2267 JY8QFUQ01BID9F unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 872 89.77 193/215 nt Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGS## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) caggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagcccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2268 JY8QFUQ01ADMXB unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 146 56.92 74/130 nt 8 6 X 8.6.X [1.17.11.X] null + No rearrangement found tctggattcaactttggcatctataccatggcctgggtccgccaggctccaaggtcttccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +2269 JY8QFUQ01AZDDJ unproductive Homsap IGHV1-18*01 F 966 94.86 203/214 nt 94.39 202/214 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [0.17.38.11] CARETTILREFIPASG#W out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggttacatctttaccacctatggtatcagttgggtgcgacaggCcccctggacaagggcttgagtggatgggatggatcaacacttacaatggtaacacgaactatggacagaggatccagggcagagtcaccatgaccacagacacatccacgagcacagcctacatggagctgaggagcctgagatctgacgacacggccgtatattattgtgcgagagaaactactatacttcgggaattcattccggcttcaggcactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2270 JY8QFUQ01CYMX9 unknown (see comment) Homsap IGHV1-NL1*01 P 90 56.79 46/81 nt 2 X X 2.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagagac +2271 JY8QFUQ01ATJJY No results +2272 JY8QFUQ01CM08J No results +2273 JY8QFUQ01BGHPH unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame + ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +2274 JY8QFUQ01DVKHO unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactanttccccgaaccggtgacggtgtcgtggaactc +2275 JY8QFUQ01BACNA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +2276 JY8QFUQ01DW7FA unknown (see comment) Homsap IGHV3-7*02 F 108 59.26 48/81 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +2277 JY8QFUQ01AO4GZ No results +2278 JY8QFUQ01BSHN4 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.37.11] CVSDLAGQKGF# out-of-frame + in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2279 JY8QFUQ01BV06C unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDNYGDYW# out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccagggaacccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2280 JY8QFUQ01DD56X productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +2281 JY8QFUQ01C07BL No results +2282 JY8QFUQ01A5997 No results +2283 JY8QFUQ01AH0X0 productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt 90.5 200/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); tctctgatgactccgtcagcagtggtcgCttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2284 JY8QFUQ01DSP02 productive Homsap IGHV3-9*01 F 792 85.25 185/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CGRIAKPGLGALDLW in-frame - cgttggattcacttttaatgaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctggggccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2285 JY8QFUQ01C92ZP unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-59*08 F (see comment) 607 75.93 164/216 nt 75.0 162/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [2.17.38.X] null - stop codons no junction found Low V-REGION identity (75,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcaggagttactactggaactCggatccggcagTccccccgggaaggcactgtaatgaagcgagtatatgtcttgcagtgggagcaccaatttaaacccctccctcaagggtctagtcaccatatcaccagacacggccaagaaccagctctccctgaagctgagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2286 JY8QFUQ01DH3KU No results +2287 JY8QFUQ01C3YS3 No results +2288 JY8QFUQ01AVZ2U No results +2289 JY8QFUQ01DWLP4 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 92 52.31 68/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +2290 JY8QFUQ01CRB5W No results +2291 JY8QFUQ01CYYET No results +2292 JY8QFUQ01B123L productive Homsap IGHV3-9*01 F (see comment) 783 84.79 184/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcatcttcagtagctactggatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2293 JY8QFUQ01B0YFD productive (see comment) Homsap IGHV4-39*02 F 951 92.27 203/220 nt 91.82 202/220 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [1.16.38.11] CARRYSWNYERFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtactaataattactactgggcctggatccgccagcccccagggaggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatngtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2294 JY8QFUQ01CU4ME productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +2295 JY8QFUQ01BIWUQ No results +2296 JY8QFUQ01DW8GO No results +2297 JY8QFUQ01DJ43Y unknown (see comment) Homsap IGHV3-16*01 ORF 93 53.51 61/114 nt 8 X X 8.X.X [25.5.X.X] null + No rearrangement found ctctggattcacctttagtagttctgccatgaactggaggagtctgggggaggcttggttcagccgggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2298 JY8QFUQ01CBV55 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 7 8 14 7.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2299 JY8QFUQ01BO7J4 No results +2300 JY8QFUQ01A1P0U No results +2301 JY8QFUQ01DFCJZ No results +2302 JY8QFUQ01BUO0C productive (see comment) Homsap IGHV1-3*01 F 961 94.84 202/213 nt 94.37 201/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 7 9 8.7.9 [0.17.38.11] CARWNNDLDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2303 JY8QFUQ01DWACQ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 412 88.46 92/104 nt 87.5 91/104 nt 8 8 X 8.8.X [1.16.1.X] null - No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 47 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggagggggctggagtgggtctcagccattagtggcagtggtagtcggacatatt +2304 JY8QFUQ01C7TE5 productive Homsap IGHV3-9*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2305 JY8QFUQ01BBS32 No results +2306 JY8QFUQ01BE96R productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F (see comment) 731 81.45 180/221 nt 81.0 179/221 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 10 7 12 10.7.12 [1.17.38.11] CASGPHGWYHFDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,45% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); tctctgggggTcgccgtcaccaccggttcctactactggacctggatccggcagcccccagggaagggactggagtggattggggatttctcctttactggggacaccaaagaaaactcctccctcaggagtcgagtcaccttatcaatagacaggatcaacaatcaggtctccctgcaattaaagtctgtgaccactgcggactcggccatgtatttctgtgcgagcggtccccatggctggtaccactttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2307 JY8QFUQ01BBCFP No results +2308 JY8QFUQ01CTLWV No results +2309 JY8QFUQ01BMIUM No results +2310 JY8QFUQ01DV17G No results +2311 JY8QFUQ01BZ5MM productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 97 of V-REGION: 'C' (1 nucleotides at position 196 to 196 in the user submitted sequence), (cause frameshift); ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaCggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +2312 JY8QFUQ01AER7A unproductive Homsap IGHV3-7*01 F 981 94.93 206/217 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGGGGVHDY# out-of-frame - ctctggattcacctttagtgactattacatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagccagatggaagtcagaaaaactatgtggactctgtgaagggccgattctccatctccagagacaacgccaagaactcactatatctgcaaatgaacagcctgagagccgaagacacggctgtgtattactgtgcgagagggggaggaggtgttcacgactattgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2313 JY8QFUQ01AXJ5N No results +2314 JY8QFUQ01A6T0C No results +2315 JY8QFUQ01CUWCS unproductive Homsap IGHV3-7*01 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSGFTRR#YW out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'T' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); gctctggaGttcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaTggggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2316 JY8QFUQ01A04I5 No results +2317 JY8QFUQ01C8C69 unproductive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 2 10 7 X 10.7.X [1.17.38.11] CATVRAG#AFDIW out-of-frame - stop codons tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtgcgcgccgggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2318 JY8QFUQ01CY2J0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD2-8*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKGASTAVMVSGTDCYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattccccttcagcacctatcccatgagctgggtccgccaggctccagggaggggactggagtgggtcgcaactataagtggtggaggttatagtatatatgacgcagactccgtgaagggcaggttcaccatctccagagacaactccaagaccaccttgtttctggaaatgaaaagtctgagagtcgatgatacggccgtctattactgtgcgaaaggggcctcgactgcagtaatggtgtctggaacagattgttacggtttggacgtctggggccacgggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2319 JY8QFUQ01A992X No results +2320 JY8QFUQ01DNZGU No results +2321 JY8QFUQ01CGAAX unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 125 54.89 73/133 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +2322 JY8QFUQ01CLP1Z No results +2323 JY8QFUQ01BQV1A No results +2324 JY8QFUQ01BKVCM No results +2325 JY8QFUQ01CY3HZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame + ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgccctggtccagggcttcttcccccgag +2326 JY8QFUQ01C1R7I productive (see comment) Homsap IGHV3-11*01 F 929 93.4 198/212 nt 92.92 197/212 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [0.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2327 JY8QFUQ01DQ243 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 264 59.49 116/195 nt 8 8 X 8.8.X [1.17.30.X] null + No rearrangement found Low V-REGION identity (59,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2328 JY8QFUQ01A0DCZ No results +2329 JY8QFUQ01BQM1M No results +2330 JY8QFUQ01DQXMN unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +2331 JY8QFUQ01A0LBC productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 8 13 8.8.13 [1.17.38.11] CATYGRFSFSPLDYW in-frame + gtctggattcgacttcagtagttatggcttccattgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctccccttgactactggggccagggaacccttgtcactgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgagaacgtggctcatcgcctgcctggtccagggcttnttccccc +2332 JY8QFUQ01BMTSW productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 806 85.78 187/218 nt 85.32 186/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.16.38.11] CARRWARQRLVMDYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) tctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggagggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca +2333 JY8QFUQ01BQB6I No results +2334 JY8QFUQ01AJEE9 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 904 91.2 197/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-16*01 F 2 8 7 16 8.7.16 [2.17.38.11] CVRYDYSRLHRSNYFGPW in-frame - gcctctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtattacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2335 JY8QFUQ01CQWZY No results +2336 JY8QFUQ01A02HL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-21*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - gctctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtttattactgtgcgagaggccgaatagtgtcggttggtatgtcaggctggttcgacccctggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2337 JY8QFUQ01AVELH No results +2338 JY8QFUQ01C3RMW unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 454 72.63 130/179 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (72,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2339 JY8QFUQ01CTDSS No results +2340 JY8QFUQ01CEGUK No results +2341 JY8QFUQ01AY1M4 No results +2342 JY8QFUQ01DVCNS No results +2343 JY8QFUQ01BR1UG productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 808 86.85 185/213 nt 85.45 182/213 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 7 17 8.7.17 [1.16.38.11] CVRDSGPSGYARYESMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 57 of V-REGION: 2 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) ctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggcgtggagtggtctcacacgtaatatggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2344 JY8QFUQ01BCK56 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*02 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*04 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*08 F or Homsap IGHV3-30*10 F or Homsap IGHV3-30*11 F or Homsap IGHV3-30*16 F or Homsap IGHV3-30*17 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-3*01 F 398 91.58 87/95 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 1 X X 16 X.X.16 [X.X.31.11] CAKDELPWDTIEYYFDYW in-frame - cctctggattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatgagctgccttgggacacaattgaatattattttgactattggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +2345 JY8QFUQ01B5CFK unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 129 55.3 73/132 nt 8 6 X 8.6.X [1.17.11.X] null - No rearrangement found stop codons ctctggattcaacgtcagtggatactggatgcactgggtccgccaagtgccaaggtcttcccgctgagcctcgacagcaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2346 JY8QFUQ01CC6VD No results +2347 JY8QFUQ01CSA21 unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag +2348 JY8QFUQ01ACBHD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTTRPRGWEPLGLDYW in-frame + ctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtaccacacggccccgggggtgggaaccacttggccttgactactggggcctggaaccctgggtcaccgtctcctcagcatcccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2349 JY8QFUQ01ACXS7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVKEDHDSGLRVLLEW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 51 of V-REGION: 'AG' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift); ctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggaggggcgtggaAGgtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2350 JY8QFUQ01DSULQ unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 708 81.99 173/211 nt Homsap IGHJ3*01 F (see comment) 88 64.0 32/50 nt Homsap IGHD3-3*02 F 1 7 8 X 7.8.X [X.17.38.11] CARIWDSWSGAFD#VG out-of-frame + Low V-REGION identity (81,99% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ4*03 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) attcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtgggggccaagggcacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +2351 JY8QFUQ01AYSZW No results +2352 JY8QFUQ01AE6X4 productive (see comment) Homsap IGHV3-11*01 F 828 87.1 189/217 nt 86.64 188/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CVREVTGVWDWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); ctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccaGtttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2353 JY8QFUQ01C3FN6 productive (see comment) Homsap IGHV3-7*01 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATDDSNGWDEVADYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); cctctggattcaccttGcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2354 JY8QFUQ01BWWEL unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CAREKVRGPP#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 93 of V-REGION: 'G' (1 nucleotides at position 180 to 180 in the user submitted sequence), (cause frameshift); cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggacGagactgagccccgaggacacggccgtctactactgtgcgagagaaaaggttcggggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2355 JY8QFUQ01DTPZS No results +2356 JY8QFUQ01DEPOD unknown (see comment) Homsap IGHV4-61*02 F (see comment) 253 82.43 61/74 nt 10 X X 10.X.X [1.13.X.X] null - No rearrangement found Low V-REGION identity (82,43% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgcctggatccggcagccca +2357 JY8QFUQ01BQYHT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +2358 JY8QFUQ01CB5R8 No results +2359 JY8QFUQ01ANI3M No results +2360 JY8QFUQ01AFJBJ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD3-10*01 F 1 8 8 19 8.8.19 [1.17.38.11] CARPAFLWFGDLPAEDGFDVW in-frame + ttctggatacagctttaccaattactggatcggctgggtgcgccaggtgcccggaaaaggcctggagtggatggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcagtaccgcctaccttcagtggagcagtctagcgacctcggacaccgccatgtattactgtgcgagaccagcttttctctggttcggggacttaccggccgaggatggttttgatgtctggggccaaggaacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactactttcccgaaccggtgacggtgtcgtggaactc +2361 JY8QFUQ01A9PVH No results +2362 JY8QFUQ01ANG04 productive (see comment) Homsap IGHV3-7*01 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ3*01 F (see comment) 151 78.0 39/50 nt Homsap IGHD3-16*01 F 2 7 8 8 7.8.8 [1.17.38.11] CARATNADVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) tctggattcacctttaggggtactggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaccataaatcacgatggaagtcaaatttactatatggaccttgtgaagggccggttcaccatctccagagacaacgccgagacctcactctatttgcaaatgaacaccctgagagccgaagacacggctgtctattactgtgcgagggcgactaatgccgacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2363 JY8QFUQ01COQPL No results +2364 JY8QFUQ01C2OA9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +2365 JY8QFUQ01B70GQ No results +2366 JY8QFUQ01BPY1E productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [1.17.38.11] CAKEGNLGYFDDW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +2367 JY8QFUQ01A250U No results +2368 JY8QFUQ01DOI0C No results +2369 JY8QFUQ01C3REN No results +2370 JY8QFUQ01B7MB6 No results +2371 JY8QFUQ01AR75U No results +2372 JY8QFUQ01CXR6M unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found ctctggattcatcttcagtagctactggatgcactggg +2373 JY8QFUQ01BA8HP unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 994 95.83 207/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPGGLPIVVVV#CYDPW out-of-frame + tctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccagggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2374 JY8QFUQ01AZPH8 No results +2375 JY8QFUQ01C3E97 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 1 8 8 11 8.8.11 [1.17.38.11] CVRHTAMERGDYW in-frame + ttctggatatgactttatcaactactggatcggctgggtgcgccagatgcccgggagaggcctggaatggatgggaatcatctttcctgatgactctgatgccagatatagtccgtccttccagggccacgtcaccatctcagccgacaagtccacaagcaccgcctacctggagtggagcagcctgaaggcctcggacaccgccatctactactgtgtgagacatacagctatggagaggggtgactactggggcccgggaaccctggtcaccgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2376 JY8QFUQ01DUOQ1 unproductive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARASTFYYDGSGYRD#FDIW out-of-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2377 JY8QFUQ01CRV4E unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 149 89.19 33/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcacgtttggcatctatgccatgagttgg +2378 JY8QFUQ01DSPAX unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 985 95.37 206/216 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [1.17.38.11] CAEIGWDKWKC#NWFDPW out-of-frame - tctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcggagatcggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgggtcatcgcctgctcgtgccaggcgttcttccccc +2379 JY8QFUQ01B3I35 No results +2380 JY8QFUQ01B036X productive Homsap IGHV4-61*03 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 10 7 12 10.7.12 [1.17.38.11] CTRHPKSNVEGDSW in-frame + ccctggtggctccgtcagcagtggtagttatttctggagctggatccggcagcccccagggcaggggctggaatggatcggttatgtctataacaatgggaacaccaattacaacccttccctcaagagtcgagtcaccatttctatagacacgtccgagaatcacgtctccctgaagctggcctctgtgaccgctgcggacacggccgtgtactactgtacgaggcacccgaagtctaatgtagagggtgactcctggggccagggagccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2381 JY8QFUQ01CUFT2 productive Homsap IGHV3-11*03 F, or Homsap IGHV3-11*05 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*03 F or Homsap IGHV3-69-1*02 P or Homsap IGHV3-7*03 F or Homsap IGHV3-71*01 P 165 68.35 54/79 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 X X 19 X.X.19 [X.X.26.11] CATDGVGSTVKLMVMGPFDFR in-frame + ctctggattcgtctttaacaactatgccatgggctggatgaacagcctgagagccgaggacacggccgtttattactgtgcgacagatggagtagggtctactgtgaagttgatggttatgggcccttttgacttcaggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2382 JY8QFUQ01BKL42 No results +2383 JY8QFUQ01CZX48 No results +2384 JY8QFUQ01BRMKY No results +2385 JY8QFUQ01B5BK5 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 492 84.06 116/138 nt 83.33 115/138 nt 8 8 X 8.8.X [1.16.12.X] null + No rearrangement found Low V-REGION identity (84,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactca +2386 JY8QFUQ01BT391 No results +2387 JY8QFUQ01AUAML productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 783 84.79 184/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcgcatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +2388 JY8QFUQ01CFLZL productive Homsap IGHV3-9*02 F 891 90.32 196/217 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + ctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga +2389 JY8QFUQ01BPI88 productive Homsap IGHV3-72*01 F 912 90.13 201/223 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 10 12 8.10.12 [1.17.38.11] CARDLGNGWGYDYW in-frame + ctctggattcatcttcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagagttgcatctaacatttacgccacagaatacgccgcgtctttcaaaggcagattcgtcatctcaagagacaattcaaggaactcattgtttctccaaatgaacagcctgaaaaccgacgacacggccatgtattattgtgctagagatctgggcaatggctggggctatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccc +2390 JY8QFUQ01A10H4 productive Homsap IGHV3-23*02 F (see comment) 220 75.31 61/81 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*02 F 3 X X 16 X.X.16 [X.X.27.11] CAKDRYPRSTAITAPDYW in-frame + Low V-REGION identity (75,31% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcccctttagcaagaacacggtgtatctgcagctgaacaacctgagagccgaggacagggccgaatattactgtgcgaaagatcgctaccctcggtcgacagctattacagcgcctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2391 JY8QFUQ01C4V3B No results +2392 JY8QFUQ01BLI3J No results +2393 JY8QFUQ01BE1BT No results +2394 JY8QFUQ01AP137 No results +2395 JY8QFUQ01BJ0UN productive (see comment) Homsap IGHV4-4*07 F, or Homsap IGHV4-59*10 F (see comment) 696 80.84 173/214 nt 80.37 172/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERGTSIGGAREFDSW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01BJ0UN ; 8 AA in Homsap_IGHV4-4*07), and low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 63 of V-REGION: 'AGAACATCTCTTCAATCCCTCCCTCAGGAGTC' (32 nucleotides at position 99 to 130 in the user submitted sequence), (cause frameshift); ttctggtggcgccatcagcgatattggctccttctggagctgggtccgacagcccgccgggagttcgctggagtacatcggacgtgtctataatagtgAGAACATCTCTTCAATCCCTCCCTCAGGAGTCgaatcaccaactacaatcctgccctaaggagtcgagtcaccatgtcagtggacacgtccaagaaccaattttacttgaggttggggtctgtgaccgccgacgacacagccgtctattactgtgcgagagagcgtggtacttcgatcggcggagcgagagaatttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2396 JY8QFUQ01CP4FS unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2397 JY8QFUQ01DMWVA No results +2398 JY8QFUQ01BLE7I No results +2399 JY8QFUQ01DV5WU unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 121 69.81 37/53 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVVWSLWYFDL## out-of-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctgggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2400 JY8QFUQ01A6HGP productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 795 84.3 188/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 10 15 8.10.15 [1.17.38.11] CTTDSFHIAVHGVFDFW in-frame + Low V-REGION identity (84,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttctgcattcatgttcaacaaagcctggatgaattgggtccgccaggctccaggaaagggactggagtgggttggccgtattaaaagtaacggcgacggtgcgacagtcgactacgctgcacccgtgaaaggccgattcaccatctcaagagatgattcacagaataccctcttcttacaaatgagcagcctgaaagccgaggacacagccgtctattattgtaccacagatagcttccatattgcagtgcatggcgtctttgacttctggggccagggagccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccaggcttcttccccca +2401 JY8QFUQ01DWTJW No results +2402 JY8QFUQ01DCD47 No results +2403 JY8QFUQ01DCID1 No results +2404 JY8QFUQ01DSY8S No results +2405 JY8QFUQ01BDK6D productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccc +2406 JY8QFUQ01DOC37 unproductive Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 882 89.4 194/217 nt 88.48 192/217 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.16.38.11] CVVSSGWLFHY# out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaagggctggagtgggtggccaacataaagcaagacggaagtgagGaaaacctttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactgggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2407 JY8QFUQ01BYXJU productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 936 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggcgtgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2408 JY8QFUQ01DJLW5 productive Homsap IGHV3-11*01 F 883 89.5 196/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARDDSCSGGSCYEYW in-frame - acctctggattcagtttcagtgactactacatgagttggatccgccaggctccagggagggggctggagtgggtttcatatattgatagcggtggtaccgccatgtactactcagactccgtgaagggccgattcaccatctccagggacaacgccaagaagtcactgtttctgcaaatgagtagcctgagagccgaagacacggccgtgtactattgtgcgagagatgactcttgtagtggtggtagctgttacgaatactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2409 JY8QFUQ01CAMWW No results +2410 JY8QFUQ01DV2EL unproductive (see comment) Homsap IGHV3-48*02 F 123 59.57 56/94 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 X X 12 X.X.12 [X.X.31.11] CAGSGRDPYGINVW in-frame + stop codons Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tctggattcaccttcaattcctataccatgatgtgggtcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2411 JY8QFUQ01C028P No results +2412 JY8QFUQ01A8UWT No results +2413 JY8QFUQ01AXKJM unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 535 71.76 155/216 nt Homsap IGHJ1*01 F (see comment) 22 75.0 6/8 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (71,76% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctgggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccaaggtcttcccgctgagcctcgacagcacccccaacgatggaagcgtggtcgtcgcatgcctggtccagggcttcttccccc +2414 JY8QFUQ01B3ST5 No results +2415 JY8QFUQ01B6YGS unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found tgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +2416 JY8QFUQ01A80C2 No results +2417 JY8QFUQ01B020G productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 281 81.4 70/86 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame - Low V-REGION identity (81,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2418 JY8QFUQ01CTP63 No results +2419 JY8QFUQ01B569F productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDYW in-frame + tctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct +2420 JY8QFUQ01BK4RL productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1046 97.29 215/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2421 JY8QFUQ01BD3L3 No results +2422 JY8QFUQ01DR0DH productive Homsap IGHV3-66*02 F (see comment) 754 84.04 179/213 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-21*01 F 3 8 7 11 8.7.11 [1.17.38.11] CARHLMVYALDVW in-frame + Low V-REGION identity (84,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaggggctggagtgggtctcagtcttatttagtactggcactgcatactacgcagactccgtgaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcccctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2423 JY8QFUQ01AVUJJ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2424 JY8QFUQ01BR14I No results +2425 JY8QFUQ01C1L00 No results +2426 JY8QFUQ01CCR5Z unproductive (see comment) Homsap IGHV1-2*02 F 822 87.38 187/214 nt 86.92 186/214 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [0.17.38.11] CARRVPPGDLW##VFDIW out-of-frame + stop codons in FR3-IMGT at codon 95 of V-REGION: 'C' (1 nucleotides at position 185 to 185 in the user submitted sequence), (cause frameshift); tggatacaccttcaacgcctactacatacactgggtgcgacaggtccctggacaagggcttgaatggatgggatacgtcaaccccagtcgtggtggcacaaactatgcacagacgtttcagggcagggtcaccttgaccagggacatgtccatcaacacagtctacttggagttgaacgggctgCaagtctaacgacacggccatttattactgtgcgaggagggtcccccctggggatctctggttatgtttttgatatctggggccaagggacacaggtcaccgtttcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2427 JY8QFUQ01DGJRC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD3-3*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKQTIFDYYYYGLDVW in-frame + ctctggattcatgtttagtagctttcccatggcctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc +2428 JY8QFUQ01DUWRL productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*04 F or Homsap IGHV3-49*05 F 1073 98.64 218/221 nt 97.74 216/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 1 7 10 11 7.10.11 [1.17.38.11] CTPWWRGGYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) tctggattcacctctgtgattatgctatgagctggctccgccaggctccagggaaggggctggagtgggtaggAtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaaccatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtaccccgtggtggcggggaggttactttgactactggggccagggaaccccggtcaccgtgtccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2429 JY8QFUQ01DS7VP unproductive (see comment) Homsap IGHV3-48*01 F 855 88.48 192/217 nt 87.1 189/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.16.38.11] CARASTFYYDGSGYRDA#FDIW out-of-frame - stop codons in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggcttcagtttgagtacttataccatgGaactgggtccgccaggctccaggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggGactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgctttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2430 JY8QFUQ01BQ23L No results +2431 JY8QFUQ01C53RL No results +2432 JY8QFUQ01BT5A6 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 909 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'GTC' (3 nucleotides at position 72 to 74 in the user submitted sequence), (do not cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggctgggagtgggGTCagtctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2433 JY8QFUQ01AJJ2J No results +2434 JY8QFUQ01CP1R5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 951 92.73 204/220 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-21*01 F 2 8 8 27 8.8.27 [2.17.38.11] CARARGGPPAEYCNDGRCRPVGTAALDIW in-frame - agcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgaagacacggctgtctattattgtgcaagagcacgaggggggcctcccgcagaatattgtaatgatggaagatgccgccccgttggaacggcggcccttgatatctggggccaagggacaatggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2435 JY8QFUQ01DNUH4 No results +2436 JY8QFUQ01CEC3V productive Homsap IGHV1-18*01 F 921 92.52 198/214 nt Homsap IGHJ6*01 F 117 65.08 41/63 nt 8 8 16 8.8.16 [0.17.38.11] CARDYIQNYYYYVMWTRH (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION tggttacacctttagcaactatggtctcagctgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcaatccttactatggtaacacagattatgcacagaaattccaggacagaatcaccatgaccacagacacatccacgggcacagcctacttggagttgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagactatatccaaaactactactactacgtgatgtggactcggcatgggcaaggcaccgacgtcaccgtctcctcagcattcccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +2437 JY8QFUQ01BMUYA unproductive Homsap IGHV3-72*01 F 1078 98.65 219/222 nt 98.2 218/222 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.16.38.11] CLRPPRYD#PG out-of-frame + in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2438 JY8QFUQ01AV39T No results +2439 JY8QFUQ01B33NP No results +2440 JY8QFUQ01C26RM No results +2441 JY8QFUQ01DT048 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDPSGSGWAFESW in-frame + gtctggattccctttcagtagagatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatggtatggtatgatggaagtaatacacaccatgcagattccgtgaagggccgattcatcatttccagagacaattccaagaataaagtgtatctgcaaatgaacagtctgagagacgaggacacggctgtctattattgtgcgagagatccgagcggcagtggctgggcctttgagtcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +2442 JY8QFUQ01CBOEK productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD3-16*01 F 2 8 7 10 8.7.10 [1.17.38.11] CAREVSDALDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 99 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctacagtgggtctctgggattaattggaatggtgctaaacaggttatgcagcctctgtgcagggccgattcaccatctccagagacaacgacaacaacgtcctgtatctgcaaatgaacagtttgagacccgaggacacggccttgtatcgctgtgcgagagaggtttcggacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca +2443 JY8QFUQ01DT5ZE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 7 8 12 7.8.12 [2.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) gcctctacattcgccttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2444 JY8QFUQ01CD3AP No results +2445 JY8QFUQ01DVY06 No results +2446 JY8QFUQ01CXH8O unknown (see comment) Homsap IGHV5-51*05 F 149 56.62 77/136 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found gttctgcatatagtttttccagttactggatcgcctgggtgcgccagatgcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2447 JY8QFUQ01AXPVH No results +2448 JY8QFUQ01DA70A productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctcggcgcctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +2449 JY8QFUQ01A2I1Q No results +2450 JY8QFUQ01A4DX4 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 817 87.32 186/213 nt 86.85 185/213 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-19*01 F 2 7 8 X 7.8.X [0.17.38.11] CAKVYTGASGGS*#FDSW out-of-frame - stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) tggattcagcttagcaactttgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtacatttagcacccattatgccgactccgtgaagggccgcttcaccatctccagagacaatttcaggagcaccttatatctgcagatgaacaacctgagagccgacgacacggccatatattactgtgcgaaagtgtacaccggtgcctcggggggatcctaattttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2451 JY8QFUQ01BB7SG No results +2452 JY8QFUQ01A3I1N productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARRPAAGSHFALDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ttctggatacaactttgacaccgattggatcgcctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctgctgactctgataccagatacagtccgtccttccaaggccaagtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagcggcctgaaggcctcggacaccgccatctattattgtgcgaggcgtccagcagctggtagccacttcgctttggacgtctggggccaggggaccacggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +2453 JY8QFUQ01BHA2N unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 845 87.91 189/215 nt 87.44 188/215 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +2454 JY8QFUQ01DSMOW No results +2455 JY8QFUQ01A868D unproductive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 930 92.99 199/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [0.17.38.11] CAKGSFDSSGRPEAFDI## out-of-frame + Other possibilities: Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggaggcaccttcagtagatatgctttcagctgggtgcgacaggcccctggacaagggcttgagtggatgggagggatcgtccctctctttggttccataaagtacgcacagaagtaccagggcagagccacgattaccgcggacgaatccacgagcacagtctacatggagctgagcagcctgagatctgacgacacggccatgtattactgtgcgaagggttcctttgatagtagtggtcgccctgaggcttttgatatctggggccaagggtacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +2456 JY8QFUQ01AT3W2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 942 92.27 203/220 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARDQSLGMPEAFDIW in-frame - agcctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2457 JY8QFUQ01C82WJ No results +2458 JY8QFUQ01BAWMT No results +2459 JY8QFUQ01DRHOK productive (see comment) Homsap IGHV3-48*01 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 7 17 8.7.17 [1.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +2460 JY8QFUQ01AY5MA productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 3 8 8 10 8.8.10 [1.17.38.11] CASFRVLESGYW in-frame + ctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2461 JY8QFUQ01B4Z6K unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 718 85.64 167/195 nt 84.62 165/195 nt 8 2 X 8.2.X [1.16.36.X] null + No rearrangement found stop codons in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) ctgtggtgggtccttcagtggtttctactagagatgcatccgccagccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgcacggtgtcgtggaactcag +2462 JY8QFUQ01C7IDB unknown (see comment) Homsap IGHV3-74*03 F 119 54.62 71/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons tctggattcaccttcagtacctactggatgcactgggtccgccaagttccaaggtcttcccgctgagcctcgacaggcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +2463 JY8QFUQ01BBMRP unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 461 70.98 137/193 nt 8 7 X 8.7.X [0.17.31.X] null + No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BBMRP ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (70,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +2464 JY8QFUQ01CU1XI productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 889 91.08 194/213 nt 90.61 193/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 6 12 8.6.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) ttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgtttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +2465 JY8QFUQ01APTCB No results +2466 JY8QFUQ01CMICY No results +2467 JY8QFUQ01AYN2M No results +2468 JY8QFUQ01DDLK7 No results +2469 JY8QFUQ01CCIQV unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 106 53.44 70/131 nt 8 8 X 8.8.X [1.17.9.X] null - No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +2470 JY8QFUQ01BL5TH unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD3-16*01 F 1 7 8 X 7.8.X [1.17.38.11] CAREVSDAFEM# out-of-frame + Other possibilities: Homsap_IGHJ3*02 and Homsap_IGHJ3*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 23 in the user submitted sequence), (cause frameshift) tctggattcatctttgatgatttggcatgaattgggtccgccaagctccagggaaggggctggagtgggtcgctggtatcagttggaatggtggcaaagcaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtgggtcaagggacaacggtcaatgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2471 JY8QFUQ01DBVCU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2472 JY8QFUQ01ATSWA unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ6*01 F 84 62.75 32/51 nt Homsap IGHD6-6*01 F 2 8 10 X 8.10.X [0.16.38.11] CTSNSWLDR# out-of-frame - in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) tggattctctttcagtaatgcctggatgaattgggtccgccaggctccagggaagggctggaatgggttggccatattaaaagggaaattgatggtgggataacaaactacgctgcacccgtgaagggcagattctccatcgcaagagatgattcaaagaatatgatgtatttgcaaatgaacagcctgaacaccgaggacacaggcgtgtattactgtacctcaaattcgtggctcgaccgctggggccagggaaccccgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +2473 JY8QFUQ01BA14W No results +2474 JY8QFUQ01CPUKD No results +2475 JY8QFUQ01DKCM5 No results +2476 JY8QFUQ01C0T7U unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 116 54.14 72/133 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +2477 JY8QFUQ01ARC7L productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2478 JY8QFUQ01CQB35 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CGKPIVGATGREMPVS## out-of-frame + ctctggattcacctttagcaactatgccatgaactgggtccgccaggttccaggggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttcctggggcccagggaaccctggtcaccgtctccgtcagcatcccctgaccagcccctaaggtcttcccgctgagcctctgcagcatccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaat +2479 JY8QFUQ01BZZLJ No results +2480 JY8QFUQ01A622C productive Homsap IGHV3-21*04 F 483 89.26 108/121 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 X 2 10 X.2.10 [X.X.38.11] CARAVSNQVDVW in-frame - ctctggattcgccttcaactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccaagatgggaacgtggtcgtcgcatgcctggtccaggcgttcttccccca +2481 JY8QFUQ01BR57P productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacttccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2482 JY8QFUQ01BKRAY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2483 JY8QFUQ01C9QBA productive (see comment) Homsap IGHV1-18*01 F 953 93.95 202/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt 8 8 8 8.8.8 [0.17.38.11] CARGDYFDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); ctggttacaGcctttaccagctatggtctcagctgggtgcgacaggcccctggccaagggcttgagtggatgggatggatcttcgGtttttaacggtaacacaaaatatgcacagcacctccagggcagagtcaccatgaccacagacacatccacggacacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagaggtgactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +2484 JY8QFUQ01BE5D4 productive (see comment) Homsap IGHV3-23*05 F 841 87.96 190/216 nt 87.5 189/216 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD3-9*01 F 2 8 7 18 8.7.18 [2.17.38.11] CVKVAGDYRTPNYGWHFDLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 97 in the user submitted sequence), (do not cause frameshift) gcctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactggatctgcaaatgaatagcctgagaggcgaagacacggccgcatattactgtgtgaaagtggccggtgactatagaactcccaactacggctggcacttcgatctctggggccgaggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +2485 JY8QFUQ01AT7WL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 489 83.1 118/142 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 X 7 10 X.7.10 [X.2.38.11] CVSDLAGQKGSW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AT7WL ; 8 AA in Homsap_IGHV3-74*01), and low V-REGION identity (83,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcaggattcaccttcagtagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2486 JY8QFUQ01B1545 No results +2487 JY8QFUQ01DUM85 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame + ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +2488 JY8QFUQ01AXUND unknown (see comment) Homsap IGHV1-8*01 F, or Homsap IGHV1-8*02 F (see comment) 242 82.86 58/70 nt 8 X X 8.X.X [0.15.X.X] null + No rearrangement found Low V-REGION identity (82,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatataccttcaccagatatgatatcaattgggtgcgacaggccactggacaagggcttcttccccca +2489 JY8QFUQ01BQ5HS unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 134 63.29 50/79 nt 8 X X 8.X.X [0.17.X.X] null + No rearrangement found stop codons ctggattcacctttagcagctatgccatgagctgggtcaaggactacttcccgaaccggtgacggtgtcgtggaactca +2490 JY8QFUQ01CL5YX No results +2491 JY8QFUQ01DV6BW No results +2492 JY8QFUQ01DRKBX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaCcctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2493 JY8QFUQ01BX9AL No results +2494 JY8QFUQ01B1UIQ No results +2495 JY8QFUQ01C7DXS No results +2496 JY8QFUQ01DT7MS No results +2497 JY8QFUQ01AFNSC No results +2498 JY8QFUQ01A5Q00 No results +2499 JY8QFUQ01BWSC5 No results +2500 JY8QFUQ01DQ3L4 No results +2501 JY8QFUQ01AXVCU No results +2502 JY8QFUQ01C1FRP No results +2503 JY8QFUQ01CPRDH productive (see comment) Homsap IGHV3-69-1*01 P (see comment) 739 89.62 164/183 nt 88.52 162/183 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 X 8 13 X.8.13 [X.16.38.11] CARGLAVILGGFDYW in-frame + Potentially, because of detected insertion/deletion however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01CPRDH ; 7 AA in Homsap_IGHV3-69-1*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 28 in the user submitted sequence), (cause frameshift) gagtgggtgccgccaggctccagggaagggctggagtgggtctcagGgcttttgtggaagtgctcctaccacacactacgcagactccgtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaacctcag +2504 JY8QFUQ01C7P46 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 913 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 76 to 78 in the user submitted sequence), (do not cause frameshift); tctacattcgcctttagcaactatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2505 JY8QFUQ01AD53G No results +2506 JY8QFUQ01DUC3R unknown (see comment) Homsap IGHV4-61*02 F 893 89.59 198/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +2507 JY8QFUQ01DTY3N productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F (see comment) 780 84.09 185/220 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-9*01 F 2 10 7 11 10.7.11 [1.17.38.11] CARILDGYFFDPW in-frame + Low V-REGION identity (84,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggtggctccatcgacactcaaaattactactggggctggattcgccagcccccagggacgggactggagtgggttggcagtgtccgctatggcgagagcacctattacaacccgaccctcaaaagtcgactcaccatatccatagacacgtccaggagccagttatccctgagactgagttctgtcaccgccgccgacacggcagtttactactgtgcgaggatcttggatggttacttcttcgacccctggggccagggaacccacgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2508 JY8QFUQ01ANCKN No results +2509 JY8QFUQ01BTEGL productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAKDFTYAFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gtctggattcacgGttcagtagttatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatcatctggtatgatggaagtaatcaatattatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacggtgtatctacaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgaaagattttacgtacgcctttgatctctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccacccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2510 JY8QFUQ01BE8LJ No results +2511 JY8QFUQ01B75Q6 No results +2512 JY8QFUQ01DIM6B unproductive Homsap IGHV3-7*03 F 918 91.71 199/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.16.38.11] CARDDSCSGGSCYEY# out-of-frame - in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) gctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaagggctggagtgtgtggccgacataaAagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtttctgcaaatgagtagcctgagagccgaagacacggccgtgtactattgtgcgagagatgactcttgtagtggtggtagctgttacgaatactgggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +2513 JY8QFUQ01AS4PV No results +2514 JY8QFUQ01DTWCT No results +2515 JY8QFUQ01AP23I productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +2516 JY8QFUQ01DQGIC No results +2517 JY8QFUQ01CA0LZ productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2518 JY8QFUQ01AJKNH unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 406 89.11 90/101 nt 8 7 X 8.7.X [1.17.X.X] null - No rearrangement found cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagggtgttgaca +2519 JY8QFUQ01DME78 No results +2520 JY8QFUQ01DBYWE No results +2521 JY8QFUQ01DJTIE unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F or Homsap IGHV7-81*01 ORF 146 60.19 62/103 nt 59.22 61/103 nt 8 8 X 8.8.X [0.16.1.X] null + No rearrangement found in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) cggttacattgttaccacctctggtttcagctgggtgcgacaggccctggacaaggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +2522 JY8QFUQ01DERGA unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD6-6*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRDSGPSGYARYESMDVW# out-of-frame + in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); ctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggcgtggaagGtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctgggggccaaagggaccgcggtcaccgtctcctcagcctccaccaagggcatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +2523 JY8QFUQ01DVV9D No results +2524 JY8QFUQ01DW5H9 productive Homsap IGHV3-66*02 F 948 93.93 201/214 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD6-13*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARDSPYSSGWSDGFDVW in-frame + ctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatatcagtggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaagaacacggtgtatcttcagatgaacagtctgagagctgaggacacggctgtgtattactgtgcgagagatagtccatatagcagcggctggtctgatggctttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag +2525 JY8QFUQ01DQLUI productive Homsap IGHV3-11*01 F 1071 99.54 216/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*02 F 3 8 8 16 8.8.16 [1.17.38.11] CARDGLSSIPRYNWFDPW in-frame - ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtggtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtttctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatgggttatcttctataccgcgatacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2526 JY8QFUQ01BMUM8 No results +2527 JY8QFUQ01CHCC5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 768 82.96 185/223 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [3.17.38.11] CARDDGGHMTLDVW in-frame - Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ccaatgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2528 JY8QFUQ01CTIK4 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 816 85.91 189/220 nt 85.0 187/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.37.11] CARRWARQRLVMDYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 130 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtactcattactattggggctggatccggcagCcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaacatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcaccctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +2529 JY8QFUQ01A4BI4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-17*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKEMIRYGDDVFGGLNVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggatttacctttagcagttatgccatgaactgggtccgccaggctccagggaaggggctgcagtgggtctctggtattagtggtggtggtgatgacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtgtattactgtgcgaaagaaatgatccgctacggggacgacgtttttggcggtctgaacgtctggggccaagggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +2530 JY8QFUQ01A9QX6 No results +2531 JY8QFUQ01AI0QW productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F (see comment) 324 84.62 77/91 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-26*01 F 3 X X 13 X.X.13 [X.X.30.11] CARFSGSYKSAFDIW in-frame + Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttctggatacatctttaccgaccagtccatcaccaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagattcagtgggagttacaaatcggcttttgatatctggggccgagggacaatggtctccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +2532 JY8QFUQ01AUAZ1 No results +2533 JY8QFUQ01DQQ6W No results +2534 JY8QFUQ01DRVXM No results +2535 JY8QFUQ01C1GF6 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*05 F or Homsap IGHV3-30*13 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 131 83.78 31/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcagcctcacttcctatggcatgaactgg +2536 JY8QFUQ01BEHNP No results +2537 JY8QFUQ01BZ8L3 No results +2538 JY8QFUQ01CSHBV No results +2539 JY8QFUQ01BX8J8 No results +2540 JY8QFUQ01AV3PU No results +2541 JY8QFUQ01AXI1X No results +2542 JY8QFUQ01DXAOK No results +2543 JY8QFUQ01AQ5RD productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 7 12 8.7.12 [1.17.38.11] CARAPGWMNPFDFW in-frame + tctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2544 JY8QFUQ01B369H No results +2545 JY8QFUQ01AEVL7 No results +2546 JY8QFUQ01DNI65 No results +2547 JY8QFUQ01B5XWQ No results +2548 JY8QFUQ01B5RFD No results +2549 JY8QFUQ01CD6UL No results +2550 JY8QFUQ01AL1NI unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*05 F 943 91.89 204/222 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 1 8 10 X 8.10.X [1.17.38.11] CVVDIPEVGVG#FDYW out-of-frame + tctggattctctttcacttatgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttgcccttattaaaagcaaaactagtggtgggacaacacactacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcagagaacacgttctatctacaaatgaatagactgaaaaccgaggacacagccgtgtattattgtgtcgtagatataccagaagttggtgtggggaatttgactactggggccagggagccctggtttccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +2551 JY8QFUQ01AENYV No results +2552 JY8QFUQ01B4RSD No results +2553 JY8QFUQ01DGLU4 No results +2554 JY8QFUQ01A6P6Z productive Homsap IGHV3-64*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcatactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2555 JY8QFUQ01CA3YC No results +2556 JY8QFUQ01DJU9H productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggttaaggactacttccccgaaccggtgacggtgtcgtggaact +2557 JY8QFUQ01DLWTU unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYLNL#DYW out-of-frame - gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatatttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2558 JY8QFUQ01DNYHK unknown (see comment) Homsap IGHV1-NL1*01 P 95 57.32 47/82 nt 2 X X 2.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagagaca +2559 JY8QFUQ01CUV3Y unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 434 77.03 114/148 nt 75.68 112/148 nt 8 8 X 8.8.X [1.17.14.X] null - No rearrangement found Low V-REGION identity (77,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtaaccattggatgaAcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagAaaattctacgtggtcgtcgcatgcctggtccagggcttcttccccca +2560 JY8QFUQ01CQGEM No results +2561 JY8QFUQ01A9PLD productive (see comment) Homsap IGHV3-7*01 F 900 90.78 197/217 nt 89.86 195/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.37.11] CARVNKDSTDMW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 169 in the user submitted sequence), (cause frameshift) cctctggattcacctttagtgactattggatgaggtggttccgccagcctccaggaaagGgggctggagtgggtggccagcataaaagaagatggaagtgagaaaggttatgtggactctgtgaagggccgcttcaccatcgccagagacaacgcccagaaatcactgttttgcagatgaacagcctgagaggcgaggacacggctgtgtattcctgtgcgagagtcaacaaggactctactgatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +2562 JY8QFUQ01BJCOA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +2563 JY8QFUQ01BXFLY productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 7 12 8.7.12 [1.17.38.11] CARAPGWMNPFDFW in-frame + tctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccga +2564 JY8QFUQ01DJ6AS unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 955 93.15 204/219 nt 91.78 201/219 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [2.17.38.11] CAKIIPPMTGVVHYTDY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'GG' (2 nucleotides at position 128 to 129 in the user submitted sequence), (cause frameshift); gcctctggattcaccGtttagccactttgccgtgacctgggtccgccaggctccagggaagggtctgGgaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaaGGgggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatattactgtgcgaaaataatcccccctatgacaggagtggtccattataccgactactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2565 JY8QFUQ01BTEHZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagcatgggagacgtggtcgtcgcatgcctggtcccaggggcttcttccccca +2566 JY8QFUQ01A053Y No results +2567 JY8QFUQ01B2881 No results +2568 JY8QFUQ01AL0BU No results +2569 JY8QFUQ01DT394 productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctca +2570 JY8QFUQ01A7UQW productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2571 JY8QFUQ01AX5SQ No results +2572 JY8QFUQ01CNY4M No results +2573 JY8QFUQ01B10SN unknown (see comment) Homsap IGHV3-33*04 F, or Homsap IGHV3-48*03 F or Homsap IGHV3-62*01 P or Homsap IGHV3-NL1*01 F 91 54.46 55/101 nt 8 7 X 8.7.X [1.17.X.X] null + No rearrangement found stop codons ctctggattcacctttagtagttctggcatgtattgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +2574 JY8QFUQ01C2LW8 productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F (see comment) 754 80.95 187/231 nt 79.65 184/231 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD3-10*01 F 3 8 10 16 8.10.16 [4.17.38.11] CARIWEPSITFLHTFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 93 of V-REGION: 'A' (1 nucleotides at position 198 to 198 in the user submitted sequence), (cause frameshift); aggggttcgggggctttcacctttggtgaCtgatgctatcagttggttccgccaggctcctgggaAaggggctggagtggattgctctccttaggagcaaaccttataattcaccaacacaattcgccacgtctgtgaaaggccgattcactgtctcaagagatgactcggaaagtgtcgcctatctgcacatgaacAagcctgcaaaccggggacacagccgtgtattattgtgccagaatatgggaaccaagtattactttccttcatacatttgatgtctggggccgagggacacgggtcaccgtttcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +2575 JY8QFUQ01DCPE5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); cctctggattcacGtttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +2576 JY8QFUQ01DQN4D productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggcactacttccccgaaccggtgacggtgtcgtggaactc +2577 JY8QFUQ01AUCEO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 528 90.0 117/130 nt 89.23 116/130 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 X 12 8.X.12 [1.3.31.11] CVKDISRSGCFEYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 38 in the user submitted sequence), (do not cause frameshift) ctctggattccagtttagcaactatgccatgagctggggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2578 JY8QFUQ01BTHDM No results +2579 JY8QFUQ01ATMQR No results +2580 JY8QFUQ01CCTYG productive Homsap IGHV3-7*01 F 940 93.06 201/216 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGHW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaatgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2581 JY8QFUQ01DTZBY No results +2582 JY8QFUQ01C70TW No results +2583 JY8QFUQ01DOFMA No results +2584 JY8QFUQ01CXJMK No results +2585 JY8QFUQ01BYHF0 No results +2586 JY8QFUQ01ANQIJ unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 805 85.65 185/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2587 JY8QFUQ01CTKHD No results +2588 JY8QFUQ01AUT05 unknown (see comment) Homsap IGHV3-66*03 F 114 58.06 54/93 nt 8 4 X 8.4.X [1.17.X.X] null - No rearrangement found cctctgggttgaccgtcagtgccgaccacatgtactgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2589 JY8QFUQ01CRUH8 No results +2590 JY8QFUQ01A3VC8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2591 JY8QFUQ01DDAOB unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [1.17.38.11] CATYGRFSF#SLDYW out-of-frame + ctctggattcacctttagcagctatgccatgaactgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctcccttgactactggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2592 JY8QFUQ01DKDYZ No results +2593 JY8QFUQ01CWD36 No results +2594 JY8QFUQ01CZQ6V productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt 86.11 186/216 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacagtgtcgtggaactcag +2595 JY8QFUQ01BGDUG No results +2596 JY8QFUQ01B1ZYW No results +2597 JY8QFUQ01DJ6HA unproductive Homsap IGHV3-72*01 F 1043 96.43 216/224 nt 94.64 212/224 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD3-22*01 F 1 8 10 X 8.10.X [1.17.38.11] CVRGLHSNYYGMDVR# out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'A' (1 nucleotides at position 172 to 172 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 184 to 184 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'A' (1 nucleotides at position 199 to 199 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgaccactacatggactgggtccgccaggctccagggaaggGggctggagtgggttggccgtagtagagacaaagttaacagttacagcacagaatacgccgcgtctgcgaagggcagattcaccatctcaagagatgaatcaaagaactcaActgtatctgcaAaatgaacagcctgaAaaagcgaggacacggccgtgtattactgtgttagaggcctacacagtaattactacggtatggacgtcagggggccaaggggaccacggtcaccgtctcctcagcatcccccgaccagcccccaagggtcttcccgctgagcctcgacagcaccccccaagatggggaaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +2598 JY8QFUQ01DHC7V No results +2599 JY8QFUQ01BAS1J unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CTREVGATDY## out-of-frame - cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2600 JY8QFUQ01DSBXN unproductive (see comment) Homsap IGHV3-72*01 F 854 87.05 195/224 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 1 8 10 X 8.10.X [1.17.38.11] CAVAAPPL#DGW out-of-frame + stop codons tctccggattcacctttagtaaatattccatgaactgggtccgccaggctccagggaaggggctggagtgggttggtcgcagtagaaacaaagctaatggttacagtacacaattcgccgcatctgtgatgggcagattcaccatctcaagagatgactcaaagaatttactatatctacaaatgagcagcctgaaaaccgaggacacggccatttattactgtgctgtcgcagcccccccgttatgacggctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagcccgaaggtcttcccgctgagcctcgacagcaccccccaatgatgggaacgtgtcgtcgcatgcctggtccagggcttcttcccc +2601 JY8QFUQ01BBOEJ No results +2602 JY8QFUQ01B1YYJ No results +2603 JY8QFUQ01BAO50 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [2.17.38.11] CATSRGSANWY#FDHW out-of-frame - gcctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtaccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2604 JY8QFUQ01CFLF8 No results +2605 JY8QFUQ01A0P1M No results +2606 JY8QFUQ01C813I productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2607 JY8QFUQ01B6GS0 No results +2608 JY8QFUQ01B2HC6 No results +2609 JY8QFUQ01BCCIF No results +2610 JY8QFUQ01AURRA No results +2611 JY8QFUQ01C91GZ No results +2612 JY8QFUQ01A92YU No results +2613 JY8QFUQ01B5Q6J productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2614 JY8QFUQ01AGB56 No results +2615 JY8QFUQ01AYDED unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 97 52.14 73/140 nt 10 9 X 10.9.X [1.17.9.X] null - No rearrangement found stop codons tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2616 JY8QFUQ01BO7UV unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 942 91.82 202/220 nt 90.91 200/220 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); agcctctggattcaccttTtagtagttttgGccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2617 JY8QFUQ01DLFYU No results +2618 JY8QFUQ01BB6CS No results +2619 JY8QFUQ01CN4JA unproductive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 X 8.7.X [1.17.38.11] CAKFGGYWRVEQPHLLF#W out-of-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaatttggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +2620 JY8QFUQ01AK0R9 unproductive Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CLAEVGGRQFDN## out-of-frame + Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccaggggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +2621 JY8QFUQ01BM964 unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-9*01 F or Homsap IGHV3-9*03 F 162 73.02 46/63 nt 71.43 45/63 nt 8 X X 8.X.X [1.11.X.X] null + No rearrangement found in FR2-IMGT at codon 43 of V-REGION: 'CGC' (3 nucleotides at position 41 to 43 in the user submitted sequence), (do not cause frameshift); ctctggattccggtttgatgattatgccatacattgggttCGCctgcctggtccagggcttcttcc +2622 JY8QFUQ01AWITC No results +2623 JY8QFUQ01C0CP5 No results +2624 JY8QFUQ01AWXRB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 748 82.65 181/219 nt 82.19 180/219 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [2.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2625 JY8QFUQ01BK4WK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2626 JY8QFUQ01DHPUK productive (see comment) Homsap IGHV4-34*06 F (see comment) 681 80.48 169/210 nt 79.05 166/210 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 7 7 14 7.7.14 [1.16.38.11] CSRGGQSAGWHSFEAW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift)in CDR1-IMGT, from codon 38 of V-REGION: 2 nucleotides (from position 26 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift) tccatggtgggtccctcagggttaccctggactggatccgccacaccgcagagaagggactggagtgattggtcaaatcaatagtgatggaaggacaacctacaactcggccctcatgggtcgagtcaccatttcaacagacacatccaagaatcagttctcgctgactgtggtttctgttgtcgccgcggacacggcaatgtattattgttcgagaggaggccaaagtgctggctggcactcctttgaagcctggggccagggaacccaggtaatcgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2627 JY8QFUQ01DTUPK No results +2628 JY8QFUQ01ASS7S No results +2629 JY8QFUQ01BCXZR No results +2630 JY8QFUQ01CAZ6G No results +2631 JY8QFUQ01A4GLP unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-16*01 ORF or Homsap IGHV3-16*02 ORF or Homsap IGHV3-19*01 P or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-30*01 F or Homsap IGHV3-30*03 F 91 95.0 19/20 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattcaccttcatta +2632 JY8QFUQ01DF84X productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRGTREWSGIDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccgattcaccatctcccgagacaacgccaagaacacgctgtatttgcaaatggacaatctcagaggcgacgacacggctctatattattgtgtaagagggacaagggaatggagcgggattgactactggggtcagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +2633 JY8QFUQ01DTGG9 productive (see comment) Homsap IGHV4-61*07 F (see comment) 766 83.56 183/219 nt 82.65 181/219 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 173 to 173 in the user submitted sequence), (cause frameshift); gtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactGgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctcCcctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggctcatcggtcttcccccatggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2634 JY8QFUQ01DMF6C No results +2635 JY8QFUQ01DFMJ0 No results +2636 JY8QFUQ01AGCI5 No results +2637 JY8QFUQ01DUWP8 No results +2638 JY8QFUQ01B5XDP unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 138 64.1 50/78 nt 8 X X 8.X.X [1.16.X.X] null - No rearrangement found ctctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +2639 JY8QFUQ01A7KJZ productive (see comment) Homsap IGHV3-7*01 F 870 88.64 195/220 nt 88.18 194/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDPYKPGSGNPGFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); agcctctggaGttcacctttagtgactatttgatgacttgggtccgccaggctccaggaaagggactggagtgggtggccaacataaaagaagatggacttgctacattctatgtggactctgtgagggaccgattcaccatctccagagacaacgccaagaactcactttatttgcaaatgaattacctgagagtcgaggacacggctgtttattattgtgcgagggatccctataaacctggttcgggcaatccgggctttgactactggggccagggagcgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2640 JY8QFUQ01BJTTM unproductive Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.16.38.11] CAKGVVTATLTT## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaagggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggtggtaacggcgaccttgactactgggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2641 JY8QFUQ01DCFZ0 No results +2642 JY8QFUQ01BF83J unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F (see comment) 366 67.82 118/174 nt 8 10 X 8.10.X [1.17.21.X] null - No rearrangement found Low V-REGION identity (67,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2643 JY8QFUQ01DOIT3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactanttccccgaaccggtgacggtgtcgtggaactc +2644 JY8QFUQ01DPYJO No results +2645 JY8QFUQ01CIJUJ No results +2646 JY8QFUQ01ATNFH No results +2647 JY8QFUQ01C4NTG No results +2648 JY8QFUQ01C2I90 No results +2649 JY8QFUQ01DXF41 productive (see comment) Homsap IGHV3-7*01 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.37.11] CAISSGYYSTGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 78 of V-REGION: 1 nucleotides (from position 138 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccactccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2650 JY8QFUQ01BY9AG productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-3*01 F 1 8 8 20 8.8.20 [0.17.38.11] CARDHRSGALEWSHHYHGMDVW in-frame + tggttacatcttcacccactatggtatcaactgggtgcgccaggcccctggacaagggcttgagtggatgggatggatcagcgcctacagtggtaacacaaagtatgcacagaaggtccagggcagagtcaccatgaccacagacacttccacgagtacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagatcacagaagcggggctttggagtggtctcaccactaccacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +2651 JY8QFUQ01BG6CL No results +2652 JY8QFUQ01C062K No results +2653 JY8QFUQ01AS67A No results +2654 JY8QFUQ01B1X0K No results +2655 JY8QFUQ01CUV81 No results +2656 JY8QFUQ01CJ8FQ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 901 90.41 198/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDLYGADDLW in-frame - acctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +2657 JY8QFUQ01BFUYH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVKDISRSGCFEYW in-frame + ctctggattccagtttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +2658 JY8QFUQ01BNOH6 No results +2659 JY8QFUQ01CYL1O No results +2660 JY8QFUQ01AVGL3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1075 100.0 216/216 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 20 8.8.20 [1.17.38.11] CAKAAYYYGSGSISSSTHFDYW in-frame + tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagccgcgtattactatggttcggggagtatcagttcctctacccactttgactactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaaccc +2661 JY8QFUQ01BMHAR unknown (see comment) Homsap IGHV3-52*01 P, or Homsap IGHV3-52*02 P or Homsap IGHV3-52*03 P or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 101 53.08 69/130 nt 8 6 X 8.6.X [1.17.10.X] null + No rearrangement found cctctggattcatcttcagtagctactggatgcactgggtccgccaagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +2662 JY8QFUQ01DESM8 No results +2663 JY8QFUQ01BJPBW No results +2664 JY8QFUQ01DLJH0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 834 86.82 191/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [2.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame - agcctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2665 JY8QFUQ01C1KS5 No results +2666 JY8QFUQ01BDWKJ No results +2667 JY8QFUQ01DQW9S No results +2668 JY8QFUQ01ABSTL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatcatgcaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2669 JY8QFUQ01APACT productive (see comment) Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 393 91.49 86/94 nt 90.43 85/94 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD5-18*01 F 3 X X 15 X.X.15 [X.X.31.11] CARSDEEYSYGDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'ACTAT' (5 nucleotides at position 21 to 25 in the user submitted sequence), (cause frameshift); gtctggattcaccttcagtaACTATgagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatcggacgaggaatacagctatggggatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2670 JY8QFUQ01BI2SK unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 161 53.17 109/205 nt 8 8 X 8.8.X [1.17.34.X] null + No rearrangement found stop codons ctctggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2671 JY8QFUQ01ABL1C unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 481 68.98 149/216 nt 68.52 148/216 nt Homsap IGHJ1*01 F (see comment) 27 77.78 7/9 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (68,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 51 of V-REGION: 'GA' (2 nucleotides at position 66 to 67 in the user submitted sequence), (cause frameshift); tctggatttacctttacaaattattggatgagctgggtccgccaggctccagggaggggcgtggaGAgtgggtggccagcgtaaaacaagatggaggtgagaaatactatgtggactctgtgaagggccgattcaccatccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2672 JY8QFUQ01AD0NY productive (see comment) Homsap IGHV4-61*08 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 10 7 11 10.7.11 [1.17.37.11] CARGRDAYKVGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 87 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) tctggtgactccgccagcagtggtgattcgtactggagctggatccggcagcccccagggaagggactggagtggattggatatatctataagagtggggacaccgattataacccctccctcaggagtcgagtcaccatatcagtggacacgtccaagacccagtttccctgaagctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgaggggaagagatgcctacaaggtgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2673 JY8QFUQ01BK12H No results +2674 JY8QFUQ01BY9V7 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*03 F 828 88.94 185/208 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 6 8 21 6.8.21 [X.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + ctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2675 JY8QFUQ01CJ2BM No results +2676 JY8QFUQ01BRMG1 No results +2677 JY8QFUQ01BNM74 unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 137 55.4 77/139 nt 10 7 X 10.7.X [1.17.10.X] null - No rearrangement found tctctggtggctccatcagcagtagtagttactactggggctggatccgccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2678 JY8QFUQ01BIWCY No results +2679 JY8QFUQ01BU16O productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [2.16.38.11] CAKDGPGGGWYAEQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 72 in the user submitted sequence), (cause frameshift) gcgtctggattcagtttcagtgactatggcatgcactgggtccgccagactccaggcaaggggctggagtggtggcagttatttcatatgatgggagagagaagtactatgcagactccctgaagggccgattcaccacctccagagacaactccaagaaaatgctgtatctccaagtgaatagcctgagacctggagacacggctgtgtattactgtgcgaaagatgggccggggggtggctggtacgctgagcagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2680 JY8QFUQ01DPH29 No results +2681 JY8QFUQ01BXM5S unknown (see comment) Homsap IGHV2-26*01 F, or Homsap IGHV2-5*01 F or Homsap IGHV2-5*02 F or Homsap IGHV2-5*03 F or Homsap IGHV2-5*04 F or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F or Homsap IGHV2-70*09 ORF or Homsap IGHV2-70*12 F 50 100.0 10/10 nt X X X X.X.X [3.X.X.X] null + No rearrangement found accctcacgc +2682 JY8QFUQ01BL8LZ No results +2683 JY8QFUQ01CYWI2 No results +2684 JY8QFUQ01BYMDC No results +2685 JY8QFUQ01CEK8F unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 106 53.44 70/131 nt 8 8 X 8.8.X [1.17.9.X] null - No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +2686 JY8QFUQ01ACUD8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 361 88.17 82/93 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 1 X X X X.X.X [X.X.31.11] CANWLSGHILSLTT# out-of-frame + tctggattcaccttcagcaaagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcgggacacattctaagtttgactactgggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +2687 JY8QFUQ01CCFND unknown (see comment) Homsap IGHV4-61*02 F (see comment) 712 80.82 177/219 nt 10 7 X 10.7.X [2.17.37.X] null - No rearrangement found Low V-REGION identity (80,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgccctttgtacacaccgcccgtcgctactaccgattggatggtttagtgaggccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2688 JY8QFUQ01A5VSB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2689 JY8QFUQ01DFS3F productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 733 82.41 178/216 nt 81.02 175/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 7 8 13 7.8.13 [1.17.38.11] CAKDQYGSPSDFDNW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'GAG' (3 nucleotides at position 83 to 85 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) ctcagggttcgttttgagaaatacgccatgagttgggtccgccaggctcccggaaaggggctggagtgggtctcggctattgGAGgtgttgatgatgttggcacatactacgcagcctccgtgaAagggtcggttcaccatatccagagacgattccagggagattctctatctacaaatgagtaacctgagagtcgacgatacggccgtctattactgtgcgaaagatcaatatgggagcccatccgactttgacaactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2690 JY8QFUQ01BE5CI No results +2691 JY8QFUQ01A8RAK unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 102 91.67 22/24 nt 7 X X 7.X.X [0.X.X.X] null + No rearrangement found tccgggacagtgtctctagcaaca +2692 JY8QFUQ01AUQRD No results +2693 JY8QFUQ01A2OX9 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 792 85.25 185/217 nt 84.33 183/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); ctctgaattcagtttcactgaccaccacatgagctgggtccgccaagctccaggcaaGggggctggtgtgggtctcaCgcattaaaaagtgatgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcactccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2694 JY8QFUQ01C3F7Z No results +2695 JY8QFUQ01BAA94 unproductive (see comment) Homsap IGHV3-48*01 F 999 95.85 208/217 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CARVGSDA##FDVW out-of-frame + stop codons ctctggattcaccctcagtagctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtattagtagtggtaccatatactatgcagactctgtgaagggccgattcaccatctccagggacaatgccgagaactcactgtatctgcaaatgagcagcctgagagccgacgacacggctgtgtattactgtgcgagagttgggagcgacgctttcttttgatgtctggggccaagggacaacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +2696 JY8QFUQ01DW16O No results +2697 JY8QFUQ01A7HLN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame + cctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggaccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +2698 JY8QFUQ01A4ZVI No results +2699 JY8QFUQ01B7LRA productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 844 86.94 193/222 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-22*01 F 2 8 10 11 8.10.11 [1.17.38.11] CTWDSTGYFRLTW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggactcactttcagtgacgcctggatgacctgggtccgccaggttccagggaaggggctggagtgggttgcccatattagatggaactctgatgactggaccacagactacgctactcccgtgaagggcagattcaccatctcaaaagatatttcagagaacacgctgtatctacaaatgaacagcctgataagcgaggatacaggcgtttattactgtacctgggacagcactggttattttcggcttacctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2700 JY8QFUQ01CTU0J No results +2701 JY8QFUQ01BH8NM unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 387 76.3 103/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (76,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +2702 JY8QFUQ01BU9Y0 No results +2703 JY8QFUQ01BW717 No results +2704 JY8QFUQ01AZEHJ No results +2705 JY8QFUQ01DK8X9 No results +2706 JY8QFUQ01B6N08 No results +2707 JY8QFUQ01A9VOL No results +2708 JY8QFUQ01BD45K No results +2709 JY8QFUQ01BTJRN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 94 52.24 70/134 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2710 JY8QFUQ01DANVN productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +2711 JY8QFUQ01DFS2N No results +2712 JY8QFUQ01AORCI productive Homsap IGHV4-4*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [1.17.38.11] CARGKDYYDTTGSLEDGFDIW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctctggtggctccataagaagttactattggagttggatacggcactccgccgggaagggactggagtggatcgggcgcatatatgacagtggtagtacaaactacaatccctccctcaagagtcgagtcagcatgtcagtggacacgtccaagaaccaggtctccctgaagttgatctctgtgaccgccgcggacacggccatgtattattgtgcgagagggaaggattactatgatacaactggctccctcgaggatggttttgatatttggggccaagggacgatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2713 JY8QFUQ01CKQ8F No results +2714 JY8QFUQ01AF005 No results +2715 JY8QFUQ01B5RIA No results +2716 JY8QFUQ01ASMQO productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 867 89.72 192/214 nt 88.79 190/214 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 7 8 17 7.8.17 [1.16.38.11] CARDSGSSDYTRYDAQDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) tctggattcagtttagttcttatggcatgaactgggtccgccaggctccaggggggggctggagtgggtctcattcattaacagtgttagtagttacaaatactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaagaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagatagcggctcgtccgactacactaggtacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctggggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +2717 JY8QFUQ01AJHPY No results +2718 JY8QFUQ01CD6TE productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctctggattcacctttgatgactatggcatgcactgggtccggcaagctccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2719 JY8QFUQ01CM9UW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*02 F 2 8 8 16 8.8.16 [1.17.38.11] CARDLASFCGGDCPIDYW in-frame + ctctggattcacctttggcaagtatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtcctagtactggttacacatactatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacagtgtatctgcaaatgaatagcctgagacgtgaggacacggctgtgtatttctgtgcgagagatctggcatcattttgtggtggtgactgccccattgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc +2720 JY8QFUQ01ARFVX No results +2721 JY8QFUQ01AV7MG unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +2722 JY8QFUQ01CEOEX productive (see comment) Homsap IGHV3-11*01 F 886 90.28 195/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.16.38.11] CARDDSCSSGSCYEYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcagtttcagtgactactacatgagttggatccgccaggctccagggaggggctggagtgggtttcGatatattgatagcggtggtaccgccatgtactactcagactccgtgaagggccgattcaccatctccagggacaacgccaagaagtcactgtttctgcaaatgagtagcctgagagccgaagacacggccgtgtactattgtgcgagagatgactcttgtagtagtggtagctgttacgaatactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2723 JY8QFUQ01AF9QC No results +2724 JY8QFUQ01CMAIQ unknown (see comment) Homsap IGHV2-5*03 F 114 51.04 98/192 nt 10 7 X 10.7.X [9.17.25.X] null - No rearrangement found gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagccccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2725 JY8QFUQ01B6T4I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 693 80.18 174/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGLGLNAVYAFDVW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcgcttttggagattatgccatgaactgggtccgccaggccccagggaagggactggagtgggtctcaggtttgagcggtagaggcgtcagcaaatattatgcagactccgtgaggggccggttctccatttccagagacaactccgggagcgaggcagtccttcaaatgagcagcctgagagtcgaggacacggccacttactactgtgcgaggggcctagggcttaatgctgtctacgcatttgacgtctggggacaggggaccacggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2726 JY8QFUQ01BUZEN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKRLEGVADDAFDIW in-frame + ctctggattcacctttagcacctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggtagtggtggcagcacattctactcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacggtgtctgtgcaaatgaacagcctgagagtcgaggacacggccgtttattattgtgtgaaaaggttggagggagtggctgatgatgcttttgatatctggggcccagggacaatggtcaccgtctcttcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2727 JY8QFUQ01AE3XC productive (see comment) Homsap IGHV4-39*02 F 957 91.93 205/223 nt 91.48 204/223 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [2.16.38.11] CARRYSWNYERFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) ctgtctctggtgactccatcagtactaataattactactgggcctggatccgccagccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2728 JY8QFUQ01DFO3S unknown (see comment) Homsap IGHV3-48*03 F 878 89.45 195/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactc +2729 JY8QFUQ01C2JX7 No results +2730 JY8QFUQ01B8GPR No results +2731 JY8QFUQ01BW0GE productive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F (see comment) 732 81.17 181/223 nt Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 10 13 8.10.13 [1.17.38.11] CAITKIDVWGGADQW in-frame + Low V-REGION identity (81,17% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcagtttcagtggctcttctgttcactgggtccgccagacttccggaaaagggctggagtggattggccgtatcagaagtaaggcgaacgataacgcggcagtgtatcgtaagccgctgacgggcaggtttttcatctccagagatgattcacagagcacggcatatctgcaactgaacaacctgggagtcgacgacacggccacatattactgtgctatcactaaaatcgatgtttggggcggcgctgaccagtggggccaggggaccctggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagcatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca +2732 JY8QFUQ01C9KPR productive (see comment) Homsap IGHV3-30*10 F (see comment) 706 81.02 175/216 nt 80.56 174/216 nt Homsap IGHJ1*01 F 152 76.92 40/52 nt Homsap IGHD1-1*01 F 1 8 8 16 8.8.16 [1.17.37.11] CSRGTTGTTDDSRLFQHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 157 in the user submitted sequence), (cause frameshift) ctctggattcagcttcggcaattacgccatgcactgggtccgccaggctccaggcaagggcctagagtgggtggctgtcataaataaggctgggaagactaaacattatatagactccgtgaagggccgattcaacgtctccagagacaactccgaaaaacactctatttggagatgaataacgtgggagttgaggacacggctgtatattattgttcgagaggtaccacggggacgacagacgactcgaggttgttccaacactggggccagggcgccctggtcaccgtttcgtcaacatccccgaccagcccccaaaggtcttcccgctgagccttgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +2733 JY8QFUQ01DIQ0Q productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame + ctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcagcgtctcctctgcatcccgaccagccccaaggtcttcctgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2734 JY8QFUQ01BE4D2 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 822 87.38 187/214 nt 86.45 185/214 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.37.11] CAKESLVRGVISYYFDDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 131 in the user submitted sequence), (cause frameshift) cctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctggttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2735 JY8QFUQ01BISA3 unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctgtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcacctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2736 JY8QFUQ01CWMWI productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2737 JY8QFUQ01CDSVQ No results +2738 JY8QFUQ01AZ6G0 No results +2739 JY8QFUQ01DTW05 unproductive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 862 87.84 195/222 nt 87.39 194/222 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 3 10 7 X 10.7.X [2.17.38.11] CARGGGWT#YFDSW out-of-frame - in FR3-IMGT at codon 67 of V-REGION: 'G' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); gtctctggtggctccgtcagcagtggtaattactactggaactggatccgccaacccccagggaagggactggagtggattggatatatctactatgctggggccaccaacGtcgaccccctccctcaagaaccgagtcaccataacgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccgtatattactgtgcgaggggcggtggctggacccctactttgactcctggggccagggaaatctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2740 JY8QFUQ01A4766 unknown (see comment) Homsap IGHV3-13*01 F (see comment) 356 67.44 116/172 nt 8 7 X 8.7.X [1.17.24.X] null - No rearrangement found stop codons Low V-REGION identity (67,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgctggattcaccctcagttcctacgacatgcactgggtccgccagactacaggaaaaggtctggagtgggtctcaggtataagcactgacggtgacacatactattcaggctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2741 JY8QFUQ01DGTPL No results +2742 JY8QFUQ01A5DCU unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +2743 JY8QFUQ01C3YG7 No results +2744 JY8QFUQ01BG981 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 858 89.25 191/214 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2745 JY8QFUQ01B9EKE unknown (see comment) Homsap IGHV3-7*01 F 1021 96.76 209/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagg +2746 JY8QFUQ01AN8VU productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 867 87.44 195/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-14*01 ORF 2 8 10 13 8.10.13 [1.17.38.11] CTADVPSPLAQNDFW in-frame + ctctggattcactttcaatggcgcctggatgaactgggtccgccaggctccagggaagggtctggagtgggttgcccgtataaaaacttttggtgaaggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcaaaaaaagggctgtatctgcagatggacagcctgagaatcgaggacacagccaagtattactgcaccgcagatgtcccgtcaccattagcgcaaaatgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2747 JY8QFUQ01BDIS1 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame - tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2748 JY8QFUQ01CU928 No results +2749 JY8QFUQ01A3EUV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2750 JY8QFUQ01BOI0A No results +2751 JY8QFUQ01CTN4T No results +2752 JY8QFUQ01DVYCW unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 X 8.7.X [4.17.38.11] CARGGPIL** (see Functionality comment) out-of-frame + stop codons, IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +2753 JY8QFUQ01BKY33 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 836 87.91 189/215 nt 86.51 186/215 nt Homsap IGHJ6*02 F 112 64.52 40/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.16.37.11] CAGSGRDPYGINVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 46 of V-REGION: 2 nucleotides (from position 54 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 167 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccgggaaggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagtcagtgttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2754 JY8QFUQ01C3COR productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + tctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcacgcctgcctggtccagggcttcttccccca +2755 JY8QFUQ01B035T productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - ctctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2756 JY8QFUQ01BT24V No results +2757 JY8QFUQ01DJJM6 productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); ctctggattcacctttagGtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaAagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttccttccccca +2758 JY8QFUQ01DEOHD No results +2759 JY8QFUQ01DWCV7 No results +2760 JY8QFUQ01CSAME productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 868 89.35 193/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame + tctggattctccgtcagtaattactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggttttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2761 JY8QFUQ01COKCL No results +2762 JY8QFUQ01ALM3T unproductive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*05 F 975 95.33 204/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [0.17.38.11] CAGDRGPVLGWFI*AK#YGLDVW out-of-frame + stop codons tggatacaccttcaccaactactatcttcactgggtgcgacaggcccccggacaagggcttgagtggatgggacggatcaacccaaacagtggtggcacaacctatgcacagaagtttcagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgagcaggctgagatctgacgacacggccgtctattactgtgcgggagatcggggtccggttttggggtggttcatataggccaaatctacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +2763 JY8QFUQ01DCCX8 unproductive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKARIYFYGSGSYSLFDY## out-of-frame + ctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggcccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2764 JY8QFUQ01A4ZWL No results +2765 JY8QFUQ01CULZK productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1026 97.24 211/217 nt 96.77 210/217 nt Homsap IGHJ6*02 F (see comment) 157 72.58 45/62 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.16.38.11] CTKDKVTVGFRGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagctatggcatgcactgggtccgccaggctccaggcaagggctggagtgggtggcaagtatatcatatgatggaagtaataaataccatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgctgtatctgcaaatgaacagcctgagaactgaggacacggctgtgtattattgtacgaaagacaaagtcacggtaggatttcgaggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2766 JY8QFUQ01BP9OK productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 808 86.85 185/213 nt 86.38 184/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-6*01 F 1 8 7 12 8.7.12 [1.17.38.11] CVRSYSRTSEFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagttttagtacctttggcatgagttggatccgccagacgccaggcaaggggctggagtgggtgacagttatatggtcggatggaactaaaaattatgcagactccgtgaagggccgattcaccatctccagagacaatgtcaagaacacggtttatctgcagatgagcagcctgagagtcgaggacacgggcgtatattattgtgtgaggtcgtatagtaggacatctgagtttgactactggggcccgggaacccaagtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +2767 JY8QFUQ01CIKHF productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 840 88.32 189/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [1.17.38.11] CTRGRSDAWELSDHW in-frame + cgacgatgggtcctgcagaaactgcttctggagttggatccgccagtccccagggaaggggctggagtggattggggaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagtcgagtcaccatatcattagacacgtccaacaaccaagtctccctgaggttgagctctgtgaccgccgcggacacggctgtgtattactgtacgcgagggcgatccgacgcgtgggaattatcggaccactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +2768 JY8QFUQ01CIGEV unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 87.56 190/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +2769 JY8QFUQ01B8KNK No results +2770 JY8QFUQ01AWBZD No results +2771 JY8QFUQ01DFX3W No results +2772 JY8QFUQ01BO9X3 productive Homsap IGHV3-33*03 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDTITMGGDVAPLFDYW in-frame + gtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +2773 JY8QFUQ01A9HGK productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + tctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2774 JY8QFUQ01C7BRV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2775 JY8QFUQ01DT5DZ No results +2776 JY8QFUQ01DP67Y productive Homsap IGHV3-11*01 F 944 93.49 201/215 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD1-26*01 F 3 8 8 16 8.8.16 [0.17.38.11] CARDGDDYRSYYYGMDVW in-frame - ctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcatggtatacctggcagactctgtgaagggccgattcatcatctccagggacaacggcgagaactcactgtatcttcaaatgaacagcctgagagccgaagacacggccgtgtattactgtgcgagagatggggacgactacaggtcgtactactatggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2777 JY8QFUQ01AZQUO No results +2778 JY8QFUQ01BEYVN No results +2779 JY8QFUQ01AW87R unknown (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F (see comment) 342 61.75 134/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (61,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattacttggaacagtggtaggataggctatgcggactcttgtattattgtgcaaaagatatggggtatacctggaagtacattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +2780 JY8QFUQ01CUCK5 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 721 82.38 173/210 nt 7 8 X 7.8.X [X.17.38.X] null - No rearrangement found Low V-REGION identity (82,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2781 JY8QFUQ01CW0TP No results +2782 JY8QFUQ01BWVQL No results +2783 JY8QFUQ01DNHMW No results +2784 JY8QFUQ01CO6CM No results +2785 JY8QFUQ01B8WN1 productive Homsap IGHV1-2*02 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDWGGTYAPLDNW in-frame - tggatacattttcaccggctactatatacattgggtgcgacaggccgctggacaagggcttgagtggatgggatacatcgacccttacagaggtgacacaaggtttgcagagaaatttcagggcagggtcaccttgaccagagacacgtccatcagtacagcctacatggaaatgaccggcctgacgtctgaggacacggccatcttttactgtgcgagagattggggtggcacgtacgcaccgcttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2786 JY8QFUQ01AGL4Y No results +2787 JY8QFUQ01DUXY7 productive Homsap IGHV3-7*01 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDPYKPGSGNPGFDYW in-frame + ctctggattcacctttagtgactatttgatgacttgggtccgccaggctccaggaaagggactggagtgggtggccaacataaaagaagatggacttgctacattctatgtggactctgtgagggaccgattcaccatctccagagacaacgccaagaactcactttatttgcaaatgaattacctgagagtcgaggacacggctgtttattattgtgcgagggatccctataaacctggttcgggcaatccgggctttgactactggggccagggagcgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgc +2788 JY8QFUQ01BZZIK No results +2789 JY8QFUQ01AQ4YS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +2790 JY8QFUQ01DWH9C productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +2791 JY8QFUQ01AU8DV productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [0.17.38.11] CAKVGNLYFFEYW in-frame - tggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2792 JY8QFUQ01A25KE No results +2793 JY8QFUQ01DCE3W productive Homsap IGHV3-7*01 F 882 89.4 194/217 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2794 JY8QFUQ01DM5DI productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*15 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F (see comment) 648 77.88 169/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-1*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRSPNHNWFDPW in-frame + Low V-REGION identity (77,88% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaaattcaataattatgcaatgcactgggtccgccagtctccaagagcggggctgcaagtgggtggcgctatatcgactgacggcaataaagaatatcatgcagactccgtgaagggccggctcaccctctccagagacaattcgaggagtacgctgtctctgcaattgcgcaacctgacagctgacgactcggctctgtattattgtgtcagatctcccaaccacaattggttcgacccctggggccagggagccctggtcactgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +2795 JY8QFUQ01BHMP6 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +2796 JY8QFUQ01CYIMP No results +2797 JY8QFUQ01AHCLK No results +2798 JY8QFUQ01BSHPP No results +2799 JY8QFUQ01BMMST unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 89 51.88 69/133 nt 8 6 X 8.6.X [1.17.12.X] null + No rearrangement found ctctggattcaccttcagctcccattggatgagctgggtccgccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2800 JY8QFUQ01AZRHY unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 705 91.07 153/168 nt 8 7 X 8.7.X [1.17.22.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AZRHY ; 8 AA in Homsap_IGHV3-11*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatct +2801 JY8QFUQ01DBTL8 No results +2802 JY8QFUQ01CLWKZ unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 412 81.97 100/122 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found Low V-REGION identity (81,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgtttctacttacaccattttctacgcagagtctgtta +2803 JY8QFUQ01B3IJX productive (see comment) Homsap IGHV3-30*01 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 7 11 8.7.11 [1.17.38.11] CACGHMRDGYDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2804 JY8QFUQ01B6DMM No results +2805 JY8QFUQ01DQ880 No results +2806 JY8QFUQ01A9EFS unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 777 85.05 182/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CARERGSGPP#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaagaggttcgggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2807 JY8QFUQ01BA7AY No results +2808 JY8QFUQ01BXHD1 No results +2809 JY8QFUQ01CH7NR productive Homsap IGHV3-72*01 F 894 89.24 199/223 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-18*01 F 3 8 10 10 8.10.10 [1.17.38.11] CANELGYCSGGG in-frame + ctctggactcaccttcagtgcccagtacttagactgggtccgccaggctccagggaagggactggagtgggttggccgtattagaagcaaaactaacagttacaccacagaatacgccgcgtctgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggcccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +2810 JY8QFUQ01BY2LS unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 120 54.55 72/132 nt 8 7 X 8.7.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +2811 JY8QFUQ01AJL5U productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 2 9 7 11 9.7.11 [1.17.38.11] CARASTLRYLDRW in-frame - tctctggtggctccatcagcagtgataattggtggagttgggtccgccagcccccagggaagggactggaatggattggggaaatatatcatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacaagtccaagagtcaattcttcctggagctgaggtctgtgaccgccgcggacacggccgtatattattgtgcgagagcctccacactacgatatcttgaccgctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2812 JY8QFUQ01C1A5Y No results +2813 JY8QFUQ01CHIH6 unproductive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F (see comment) 418 65.74 142/216 nt 65.28 141/216 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt Homsap IGHD7-27*01 F 3 8 8 2 8.8.2 [1.16.38.6] NR*R in-frame + stop codons Low V-REGION identity (65,74% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaagggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2814 JY8QFUQ01CK7KN productive Homsap IGHV4-61*03 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 10 7 12 10.7.12 [1.17.38.11] CTRHPKSNVEGDSW in-frame + tccctggtggctccgtcagcagtggtagttatttctggagctggatccggcagcccccagggcaggggctggaatggatcggttatgtctataacaatgggaacaccaattacaacccttccctcaagagtcgagtcaccatttctatagacacgtccgagaatcacgtctccctgaagctggcctctgtgaccgctgcggacacggccgtgtactactgtacgaggcacccgaagtctaatgtagagggtgactcctggggccagggagccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2815 JY8QFUQ01C3VSO No results +2816 JY8QFUQ01DU0CR productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 899 91.16 196/215 nt 90.23 194/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [1.17.38.11] CTRELRVAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); cctctggattcaccgtcagtaccaagttcatgagctgggtccgccaggctccagggaaGggggctggagtgggtctcagtaatttatcctggAtggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2817 JY8QFUQ01CN93A No results +2818 JY8QFUQ01COXWN productive Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2819 JY8QFUQ01BCGF2 No results +2820 JY8QFUQ01BTB9J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccgaccgaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcaccagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggcaactcag +2821 JY8QFUQ01C17IZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F (see comment) 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKLENSSGNEDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctgaattaacgtttgatatatatgccatgacttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactggtagtggtgataatgcctactacgcagacttcgtgaagggccgattcgccatctccagagacaattccaagaacatgttgtatttgcaaatgaacaacctgcgaggcgaggacacggccgtttattactgtgcgaaactggaaaatagcagtgggaatgaagactcctggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2822 JY8QFUQ01DGAHD productive (see comment) Homsap IGHV3-74*03 F 856 88.13 193/219 nt 87.21 191/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); gcctctggattcacGtttccacacctcctggatgGcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +2823 JY8QFUQ01BA129 No results +2824 JY8QFUQ01A5591 No results +2825 JY8QFUQ01C1UEP productive (see comment) Homsap IGHV3-9*01 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 7 8 14 7.8.14 [1.17.38.11] CARGHSYYVSSGPDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) ctctggattcagctttgatgatttgtcatgcactgggtccggcaagttccagggaagggcctggagtgggtctcaagtattacttggaatagtggtaagattgtctatgcggactctgtgaagggccgattcaccatctccagagacaacgcccagaactccctgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2826 JY8QFUQ01BHI1R productive Homsap IGHV3-48*01 F 1003 96.3 208/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDQSPGVAVAGPDYW in-frame + tctggattcaccttcagtagatatagtatgaactgggtccgccaggctccaggaaaggggctggagtgggttgcatacattagaagtagcagtagtgtcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcaaagtccgggtgtagcagtggctggtcctgattactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaangtggtcgtcgcatgcctggtccagggcttcttccccca +2827 JY8QFUQ01DM8R5 unproductive Homsap IGHV3-48*03 F, or Homsap IGHV3-48*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P (see comment) 357 75.38 98/130 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*02 F 2 X 5 X X.5.X [X.X.38.11] CATSPSDFDRRW#YW out-of-frame + Low V-REGION identity (75,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttagctttagaaccttttggatgagctggggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2828 JY8QFUQ01DF7UJ unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 531 71.43 155/217 nt 70.97 154/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (71,43% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctgggttcaccttcagtgactactacatgggctGggatccgccaggctccagggaaggggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +2829 JY8QFUQ01CSFJ0 No results +2830 JY8QFUQ01AVSNK No results +2831 JY8QFUQ01AW6PH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2832 JY8QFUQ01DWVML unproductive Homsap IGHV3-11*01 F 819 86.64 188/217 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CADIKLGDWCFDL## out-of-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattcaccttcagggactactatatgagttggattcgcctggcacctgggaaggggctggagtgggtttcatatattagtggtaatgtgtttaccaaacactacgcagactctgtgcagggccgattcaccatctccagggacaacgacaataagacagtctatctacagatggacaacctgagagccgaggacacggccgtctatttctgtgccgatataaaactgggtgactggtgcttcgatctctggggccggtggcaccctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +2833 JY8QFUQ01CDI9D No results +2834 JY8QFUQ01AZMO9 unproductive Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 912 92.06 197/214 nt 91.12 195/214 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.16.37.11] CAGAEAGLLTY## out-of-frame + in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 188 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaagggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagcccgaggacacggctgtatatttctgtgcgggggcagaggctggcttattgacgtactggggccctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2835 JY8QFUQ01BWD6M No results +2836 JY8QFUQ01AIAIN productive (see comment) Homsap IGHV3-7*01 F (see comment) 665 79.07 170/215 nt 78.14 168/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [0.17.38.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,07% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 51 of V-REGION: 'A' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); tgggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccgAgtggtgggtgccaacatatccccagacggaaatacgaaatattttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgacgagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +2837 JY8QFUQ01B38M7 No results +2838 JY8QFUQ01BQ1XG No results +2839 JY8QFUQ01DN4L1 unknown (see comment) Homsap IGHV3-9*01 F 882 89.86 195/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctcgggattcaagtttgatgaatatgccatgcactgggtccggcgagttccagggaggggcctggagtgggtctcagttataagttgggatggtgatgacatcgcctatgcggactctgtgaagggccgattcagcatctccagagacaacgccaagaactccctgtacctggaaatgagcagtctgagagttgaggacacggccttctattactgtgcaaaggatgtcacatctgaaagtcacttcttcgctttggacgtctggggccaagggtaccgcggtcaacgtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2840 JY8QFUQ01A7TW1 productive Homsap IGHV3-48*04 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDAGGSGWYLYYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagttataccatgcactgggtccgccaggctccagggaaggggctggaatgggtctcatccattagtagtagtagtactaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacggcctgagagccgaggacacggctgtttattcctgtgcgagagatgcggggggcagtggctggtacctttactactttgactcctggggccagggaaccctggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +2841 JY8QFUQ01CRE35 No results +2842 JY8QFUQ01DRLTE unknown (see comment) Homsap IGHV3-30*08 F 716 90.7 156/172 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found tctgcattcaacttcgatagctatactatccattgggtccgccaggctccaggcaaggggctagagtgggtggcacttatatcatatgatggaggtattgaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgttgtatttac +2843 JY8QFUQ01B28TZ No results +2844 JY8QFUQ01BJPML productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +2845 JY8QFUQ01CLSSD No results +2846 JY8QFUQ01AZFFH unproductive Homsap IGHV3-48*01 F 859 88.89 192/216 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARASTFYYDGSGYRD#FDIW out-of-frame + tctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2847 JY8QFUQ01B3H4D No results +2848 JY8QFUQ01CYE3A productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*03 F 142 65.38 51/78 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 X X 8 X.X.8 [X.X.26.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tccggattcacttttagtgactattggatgagttggatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2849 JY8QFUQ01C1CC3 productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaccggtgacggtgtcgtgaactcag +2850 JY8QFUQ01C2IB9 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + stop codons ctctggattcaccttcagtacatactggatgcactgggtccaccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgtaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggcgacggtgtcgtggaactcagg +2851 JY8QFUQ01DEIHL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CNLHPYGDSSDYW in-frame + ctctggactcaccttcagtcgcctctggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtatagatagtgatgggaataacataatctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaaaacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtaaccttcatccctacggtgactcctccgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +2852 JY8QFUQ01B1S0P unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 103 52.99 71/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcactttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2853 JY8QFUQ01BDCGW productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.16.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaagggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2854 JY8QFUQ01DI73D No results +2855 JY8QFUQ01BDSLH No results +2856 JY8QFUQ01BLYA9 No results +2857 JY8QFUQ01DO575 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2858 JY8QFUQ01B0VMA unknown (see comment) Homsap IGHV4-30-2*04 F, or Homsap IGHV4-34*01 F or Homsap IGHV4-34*02 F or Homsap IGHV4-34*08 F or Homsap IGHV4-34*12 F or Homsap IGHV4-34*13 F or Homsap IGHV4-38-2*01 F or Homsap IGHV4-38-2*02 F or Homsap IGHV4-39*01 F or Homsap IGHV4-39*05 F or Homsap IGHV4-59*04 F or Homsap IGHV4-59*05 F or Homsap IGHV4-59*08 F 414 91.0 91/100 nt X X X X.X.X [X.X.33.X] null + No rearrangement found stop codons tctatggagtcgagtcaccatatgagtagacacctccaagaaccagttctccctgaaggtgagctctgtgatcgccgcagacacggctgtgtattactgtgcgagacgtaagggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +2859 JY8QFUQ01DIDLY No results +2860 JY8QFUQ01AGHR6 No results +2861 JY8QFUQ01B3QIS No results +2862 JY8QFUQ01BBO0P No results +2863 JY8QFUQ01CHNGE No results +2864 JY8QFUQ01AXQ8Q No results +2865 JY8QFUQ01BFQXZ No results +2866 JY8QFUQ01DS8C4 unproductive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-7*01 F 3 8 8 X 8.8.X [1.17.38.11] CAREGGITGTTG#NWFDPW out-of-frame - ctctggattcacctttagtaactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaatcaagatggacgtgagaaatactttgtggactctgtgaagggccgattcatcatctcccgagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggctgtgtattactgtgcgagagagggcggtataactggaactacagggggaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2867 JY8QFUQ01A5YKU No results +2868 JY8QFUQ01BL86G productive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 826 87.79 187/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 7 8 12 7.8.12 [0.17.38.11] CARGPVSGWYGDFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) tggatacatcttcaaaactactatatattctgggtgcgacgggcccctggacaagggcttgagtggatgggttgggtcaaccctaacagtggtgccacacactatgcaccgaaatatcagggccgggtcaccatgaccagggacacgtcattcgccacagcctacatggatttgagcatgttgacatctgacgacacggccatgtattactgtgcgagaggccctgtcagtggttggtatggtgacttctggggccagggaaccctagtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2869 JY8QFUQ01B0XNO productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 867 89.72 192/214 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + atatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaatagtcgagtcatcatatcgatagacacgtccaagaaccaggtctccctgaagctcctctctgtgaccgccgcggacacgggtgtgtactattgtgcgaggcccacgtatagtagcggccgggacgcctttgatacctggggccaagggacgacggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2870 JY8QFUQ01C6TP1 No results +2871 JY8QFUQ01AZ8FQ productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*03 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 930 92.99 199/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 7 16 8.7.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcagtacctattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggGcagttatatcatatgatggaaaaaagtattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtacctgcaaatggacagcctgaggcctgaagacacggctgtatattactgtgccagagatgagctcccttgggatacaatagagtactactttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2872 JY8QFUQ01B8ECU productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + ctctggactcagtttcactaacgcctggatgagctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttct +2873 JY8QFUQ01AEE1L No results +2874 JY8QFUQ01C4IDC No results +2875 JY8QFUQ01AYEER productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.37.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 124 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgagggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagccctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2876 JY8QFUQ01CTAVK unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 95 82.14 23/28 nt 7 X X 7.X.X [2.X.X.X] null + No rearrangement found tctccgggggacagtgtctctagcaaca +2877 JY8QFUQ01AYTFX No results +2878 JY8QFUQ01BJDN7 productive Homsap IGHV1-24*01 F 956 94.81 201/212 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 7 8 7 7.8.7 [X.17.38.11] CAIGAMATW in-frame + cggaaaacctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +2879 JY8QFUQ01AOOZC No results +2880 JY8QFUQ01BQN6H No results +2881 JY8QFUQ01C9EJA unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 270 68.25 86/126 nt 8 8 X 8.8.X [1.17.7.X] null - No rearrangement found Low V-REGION identity (68,25% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +2882 JY8QFUQ01AS3R6 No results +2883 JY8QFUQ01CE8RM No results +2884 JY8QFUQ01CT2ZA productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2885 JY8QFUQ01A0ZPP No results +2886 JY8QFUQ01CIO2I unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 493 92.92 105/113 nt 92.04 104/113 nt 8 8 X 8.8.X [1.16.4.X] null + No rearrangement found in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaagggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagac +2887 JY8QFUQ01BXRY4 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [2.17.38.11] CVRDSGPSGYARYESMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2888 JY8QFUQ01BZZMG No results +2889 JY8QFUQ01DE40U productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARDQSLGMPEAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'AG' (2 nucleotides at position 38 to 39 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtcgctatagcatgaactAGggtgccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2890 JY8QFUQ01DAKI0 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 559 78.57 143/182 nt 8 8 X 8.8.X [1.17.26.X] null + No rearrangement found Low V-REGION identity (78,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccgaaccggtgacggtgtcgtggaactcag +2891 JY8QFUQ01DMMHT No results +2892 JY8QFUQ01CAJ88 No results +2893 JY8QFUQ01DCYGN productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2894 JY8QFUQ01ADWC9 No results +2895 JY8QFUQ01DV6H5 productive (see comment) Homsap IGHV1-2*02 F 939 93.46 200/214 nt 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 83 to 88 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacgGggcccctggacAaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2896 JY8QFUQ01DPNFS unknown (see comment) Homsap IGHV3-7*01 F 953 93.95 202/215 nt 93.02 200/215 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggaggggctggagtgggtggccaacataaagGcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccagccccaaggtcttcccgctgagcctctgcagcacccagcagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +2897 JY8QFUQ01A7VUV productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 948 91.93 205/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.38.11] CTHLREEMSYEW in-frame + ctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaatcacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +2898 JY8QFUQ01DXIXR unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 154 89.47 34/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcaccttcagtcagtactggatgtactggg +2899 JY8QFUQ01AEOM7 No results +2900 JY8QFUQ01CEVZB unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 971 94.88 204/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [0.17.38.11] CARDTLEVVSNMDDAFDL## out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaattacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2901 JY8QFUQ01COTVM No results +2902 JY8QFUQ01CV25T productive Homsap IGHV3-48*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +2903 JY8QFUQ01C113P No results +2904 JY8QFUQ01CUZAY No results +2905 JY8QFUQ01CRNOZ unknown (see comment) Homsap IGHV3-74*03 F, or Homsap IGHV3-NL1*01 F 124 55.74 68/122 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found tctggattcaccttcagtagctactggatgcactgggtccgccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +2906 JY8QFUQ01C7IZ8 No results +2907 JY8QFUQ01COZH8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAREGGRGSSSEDYFDYW in-frame + ctctggattcaccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaatggtgcttacatatactacgcagactcaatggagggccgattcaccatctccagagacaacgccaggaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgcgagagggggggcggggcagttcgtcggaagactactttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2908 JY8QFUQ01A186V No results +2909 JY8QFUQ01C9067 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 83 51.54 67/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found ctctggattcaccttcagctcccattggatgagctgggtccgccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +2910 JY8QFUQ01C4OEJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +2911 JY8QFUQ01A9CVU No results +2912 JY8QFUQ01BSB46 No results +2913 JY8QFUQ01ASL2A No results +2914 JY8QFUQ01CF7TY productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); cctctggattcacCctttggttattatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2915 JY8QFUQ01CTQQY unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CARALIVVAGAPVYW# out-of-frame + ctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcgccatctcaagagacaacgacaagaactcactgtatctgcaaatgaccagcctgagagccgaggacacggctgtctactactgtgcgagagccctaatagtagtggctggtgcccctgtctattgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2916 JY8QFUQ01DEGFN productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2917 JY8QFUQ01DOW2F unproductive Homsap IGHV3-33*03 F 927 92.17 200/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDGGSSGWFGRC#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggcagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2918 JY8QFUQ01AFH3O No results +2919 JY8QFUQ01ATHAC unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2920 JY8QFUQ01AKNG3 No results +2921 JY8QFUQ01BAEXS No results +2922 JY8QFUQ01DXCKR No results +2923 JY8QFUQ01AWHNG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 915 90.91 200/220 nt 90.45 199/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [2.17.38.11] CANELGYCSGGG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); agcctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgAaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtggggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2924 JY8QFUQ01A073Z productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKSVSSGWPIDEIDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 2 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) ctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggaggggcgtgggagtgggtctcagccattagtggcagtggtagtcggacatattacgcagactccgtgaagggccggttcaccatctccagagacaagtccaagaaaacgttgtatctacaaatgaacagcctgagagccgaggacacggccactttctattgtgcgaagagtgtgagtagtggctggccgatcgacgaaattgactactggggccaggggacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2925 JY8QFUQ01A54Y4 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +2926 JY8QFUQ01C21UC No results +2927 JY8QFUQ01B32AH No results +2928 JY8QFUQ01DFRMM productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 978 94.09 207/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 9 9 14 9.9.14 [X.17.38.11] CARGGDYYDSGGLDYW in-frame + ggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtgattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +2929 JY8QFUQ01C2MXI No results +2930 JY8QFUQ01BCJET productive (see comment) Homsap IGHV3-11*01 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARGYSYGCFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'GGAGGGACT' (9 nucleotides at position 89 to 97 in the user submitted sequence), (do not cause frameshift); ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcaaacatcaatagtGGAGGGACTagtgggaggaccatatattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagaggatacagctatggctgctttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2931 JY8QFUQ01CHVRC No results +2932 JY8QFUQ01C6A6Y unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 890 97.33 182/187 nt 8 8 X 8.8.X [2.17.27.X] null - No rearrangement found gcctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcc +2933 JY8QFUQ01AVPQN unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 705 91.07 153/168 nt 8 7 X 8.7.X [1.17.22.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AVPQN ; 8 AA in Homsap_IGHV3-11*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatct +2934 JY8QFUQ01BHHKX productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + ctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2935 JY8QFUQ01BHJF4 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.16.38.11] CAGSGRDPYGINVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccgggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2936 JY8QFUQ01AMZZA productive (see comment) Homsap IGHV4-61*02 F 890 90.7 195/215 nt 87.91 189/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 7 13 8.7.13 [2.16.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'TGGTTA' (6 nucleotides at position 24 to 29 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 218 to 218 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) gtctccggtggctccatcagtacTGGTTAttactactgGgagctggatccggcagtccgccgggaagggactgaatggattgggcgcatgtctgccagagggggAcagcaactacaAacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtaCtttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2937 JY8QFUQ01B8EPZ No results +2938 JY8QFUQ01DH1RB No results +2939 JY8QFUQ01DAIQP No results +2940 JY8QFUQ01DDO4S No results +2941 JY8QFUQ01DTUTS No results +2942 JY8QFUQ01DS5IV No results +2943 JY8QFUQ01BJXDC unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F (see comment) 235 60.37 99/164 nt 7 8 X 7.8.X [X.17.22.X] null - No rearrangement found Low V-REGION identity (60,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atacaccttcagcaactactatagacactgggtgcgacaggcccctggacaagggcttgagtggatgggaatgatcagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +2944 JY8QFUQ01C1TQQ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 169 58.78 77/131 nt 8 7 X 8.7.X [1.17.10.X] null + No rearrangement found tctggattcaccttcagcaaccataacatgaactgggtccgccaggctcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +2945 JY8QFUQ01ALRLE unproductive Homsap IGHV1-3*01 F (see comment) 783 84.79 184/217 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD2-8*02 F 1 8 8 X 8.8.X [1.17.38.11] CARDGYLPGNGAD#W out-of-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagtcttaataactactggatgacctgggtccgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgactttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +2946 JY8QFUQ01C7XPE No results +2947 JY8QFUQ01CNQRD No results +2948 JY8QFUQ01C2CGB No results +2949 JY8QFUQ01AB3LB unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CAKDLVVTSIGPQGIHGH## out-of-frame + ctctgggttcacctttagcagctatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaagtatcagttttagtggtgagagaacatattatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacagtacatttgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaagatctggtggtgactagtattggcccccagggaatccatggccactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +2950 JY8QFUQ01DIUF8 productive Homsap IGHV3-7*01 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDPYKPGSGNPGFDYW in-frame + ctctggattcacctttagtgactatttgatgacttgggtccgccaggctccaggaaagggactggagtgggtggccaacataaaagaagatggacttgctacattctatgtggactctgtgagggaccgattcaccatctccagagacaacgccaagaactcactttatttgcaaatgaattacctgagagtcgaggacacggctgtttattattgtgcgagggatccctataaacctggttcgggcaatccgggctttgactactggggccagggagcgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2951 JY8QFUQ01CLVLV No results +2952 JY8QFUQ01A6B5R productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [2.17.38.11] CTKEGNLGYFDDW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) gcctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtacgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2953 JY8QFUQ01DO9XE No results +2954 JY8QFUQ01AF5OM No results +2955 JY8QFUQ01DLOAU unknown (see comment) Homsap IGHV3-11*01 F 954 93.55 203/217 nt 93.09 202/217 nt 8 7 X 8.7.X [2.17.38.X] null - No rearrangement found in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) agcctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2956 JY8QFUQ01CCZ4E unproductive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 1 10 7 X 10.7.X [1.17.38.11] CARCPNYNIGTR#FDYW out-of-frame - tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +2957 JY8QFUQ01A22P2 No results +2958 JY8QFUQ01BA422 productive (see comment) Homsap IGHV3-7*01 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 7 8 10 7.8.10 [1.17.38.11] CIMDLVGRADYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) cctctggattcaccttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2959 JY8QFUQ01AVP09 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F 335 88.37 76/86 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 X X 10 X.X.10 [X.X.28.11] CARLGQLALDYW in-frame - tcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2960 JY8QFUQ01AG0D6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 833 87.16 190/218 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARLRSFGDYPLDVW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2961 JY8QFUQ01DROJA No results +2962 JY8QFUQ01B4VR2 unproductive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.37.11] CARDLEVPTI*W#YW out-of-frame - stop codons in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2963 JY8QFUQ01DU9R7 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt 94.42 203/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcgatagttactacCtggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +2964 JY8QFUQ01CW9IN unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 770 83.49 182/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagccccgaggacacggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagcatggaatgcgtggtcgtcgcatgcctggtccagggcttcttccccca +2965 JY8QFUQ01C9BGT No results +2966 JY8QFUQ01AG377 unproductive Homsap IGHV3-7*01 F 938 92.99 199/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [0.17.38.11] CVRDRFMIVVVMSLGNWG#YSDHW out-of-frame - tggattcacatttagtaactactggatgagctgggtccgccaggntccagggaaggggctggagtgggtggccaacntaaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctgtgtgagagatcgatttatgatagtagtggttatgagtttggggaattgggggactactctgaccactggggccagggaacccaggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2967 JY8QFUQ01CA2V4 productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +2968 JY8QFUQ01AAUM2 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 7 8 14 7.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2969 JY8QFUQ01BODE6 productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-24*01 ORF 2 8 8 8 8.8.8 [1.17.38.11] CARGRPQPHW in-frame + ctctggattcacctttagtacctattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataacgccagatggaagtgacagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgctaagagttcactgtttctccaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggacggccccaaccccactggggccggggaaccctggtcatcgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc +2970 JY8QFUQ01CU3QA No results +2971 JY8QFUQ01BH32Y No results +2972 JY8QFUQ01DVZ77 No results +2973 JY8QFUQ01DALUO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctacattcgGcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattaatgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2974 JY8QFUQ01DV5EE No results +2975 JY8QFUQ01AERR3 No results +2976 JY8QFUQ01B35KF No results +2977 JY8QFUQ01AHF1U No results +2978 JY8QFUQ01BPQ6O productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2979 JY8QFUQ01AY2PJ unproductive (see comment) Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [1.17.38.11] CARPAGAG*PFFA#YYSGLDVW out-of-frame + stop codons ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggcagggtgacccttttttgccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2980 JY8QFUQ01DVBKX unknown (see comment) Homsap IGHV3-48*02 F 949 93.06 201/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggattcagcttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccataaactatgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +2981 JY8QFUQ01CTJRF unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 157 57.46 77/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +2982 JY8QFUQ01AM3C3 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2983 JY8QFUQ01DU3W2 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 935 91.07 204/224 nt 90.62 203/224 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [1.17.38.11] CTTAPSETYATEYFAMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 185 to 185 in the user submitted sequence), (cause frameshift); cctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatTgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2984 JY8QFUQ01A0AUL unknown (see comment) Homsap IGHV3-66*02 F (see comment) 649 82.2 157/191 nt 81.68 156/191 nt 7 7 X 7.7.X [1.17.31.X] null + No rearrangement found stop codons Low V-REGION identity (82,20% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) tctggattcaccgtcaatagaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaaggactacttcccgaaccggtgacggtgtcgtggaactcag +2985 JY8QFUQ01C4BFT No results +2986 JY8QFUQ01BHV1C productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 66 of V-REGION: 'G' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacaGccctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2987 JY8QFUQ01AB23J unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 471 71.28 139/195 nt 70.77 138/195 nt 8 7 X 8.7.X [1.17.31.X] null + No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AB23J ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (71,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 119 in the user submitted sequence), (cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgagggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2988 JY8QFUQ01DQCQO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +2989 JY8QFUQ01BHPGU No results +2990 JY8QFUQ01BLE2H No results +2991 JY8QFUQ01DEYF4 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 811 85.84 188/219 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [2.17.38.11] CVRDLNWSFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2992 JY8QFUQ01A0J40 unknown (see comment) Homsap IGHV3-48*01 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT at codon 59 of V-REGION: 'GGAGGGACT' (9 nucleotides at position 89 to 97 in the user submitted sequence), (do not cause frameshift); ctctggattcaccttcaaaaagtatggcatgaactggatccgccaggctccagggaaggggctggagtggatttcaaacatcaatagtGGAGGGACTagtgggaggaccatatattacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +2993 JY8QFUQ01BCT87 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 611 75.81 163/215 nt 75.35 162/215 nt 7 8 X 7.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) tctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2994 JY8QFUQ01DSKER unknown (see comment) Homsap IGHV3-13*05 F 98 50.27 94/187 nt 8 6 X 8.6.X [1.17.30.X] null - No rearrangement found tctggactcaccttcagtagcttcgacatgcactgggtccgcaaacctacacgaaaagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +2995 JY8QFUQ01C2Q5E No results +2996 JY8QFUQ01C602K No results +2997 JY8QFUQ01AWD51 No results +2998 JY8QFUQ01AOWN0 unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*04 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*03 F or Homsap IGHV3-66*04 F (see comment) 259 72.12 75/104 nt 8 7 X 8.7.X [1.17.1.X] null + No rearrangement found Low V-REGION identity (72,12% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggcttcaccgtcaataacaactacatgggctgggtccgccaggctccagggaaggggctggagtgggtcatcgcctgcctggtccagggcttcttcccca +2999 JY8QFUQ01CUPL9 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [1.17.38.11] CSNGYGDFPRR## out-of-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3000 JY8QFUQ01DN0GK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'A' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggagggAccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3001 JY8QFUQ01AH6J6 unproductive (see comment) Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CATSPLR*LLGRT#YW out-of-frame - stop codons cctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctcccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3002 JY8QFUQ01ASCI5 No results +3003 JY8QFUQ01CJAMU No results +3004 JY8QFUQ01AU72L No results +3005 JY8QFUQ01BFHSP productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctgggcaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3006 JY8QFUQ01AXUG2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDLTGYSSERNYW in-frame + ctctgggttcacctttagcagctatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaagtatcagttttagtggtgagagaacatattatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3007 JY8QFUQ01DP8EA productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3008 JY8QFUQ01BYFM4 productive Homsap IGHV3-11*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3009 JY8QFUQ01B7IXH No results +3010 JY8QFUQ01AV68T productive Homsap IGHV3-9*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + ctctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3011 JY8QFUQ01DIUW1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [2.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) agcctccgaattcatccttgacagttatgccatgagttgggtccgcaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3012 JY8QFUQ01AILJF No results +3013 JY8QFUQ01A018V productive Homsap IGHV4-61*02 F 811 85.84 188/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARCPNYNIGTRGFDYW in-frame + tctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3014 JY8QFUQ01C7SVR unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.16.38.11] CARDPYNGGGYSAFDI# out-of-frame + Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaagggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgcaaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagacccctataatggtggtggttatagtgcttttgatatctggggccaaggacaatggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3015 JY8QFUQ01CQ4I9 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CTKRLSGRPLVESGAP#FFDDW out-of-frame + stop codons cctctggattcacctttagcgactatggcatgagttgggtccgccaggctccagggaagggactggagtgggtctcaagtattatcgctaatggtggtgacacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagatgaacagccttagaggcgaggacacggccgtatattattgtacgaaaagactatccggacggccgcttgttgaatcaggtgcgccccttctttgacgactgggaccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3016 JY8QFUQ01DC1W2 No results +3017 JY8QFUQ01DSY6A productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CAREKGSGPPTGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggccaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacgtgtcgtggaactca +3018 JY8QFUQ01AUI27 No results +3019 JY8QFUQ01ASKXZ productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*03 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 7 16 8.7.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 2 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtacctattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcatatgatggaaaaaaagtattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtacctgcaaatggacagcctgaggcctgaagacacggctgtatattactgtgccagagatgagctcccttgggatacaatagagtactactttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3020 JY8QFUQ01BE8R5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame - cctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3021 JY8QFUQ01C7K91 No results +3022 JY8QFUQ01CEWEC No results +3023 JY8QFUQ01C6CVD No results +3024 JY8QFUQ01DAS90 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 504 92.31 108/117 nt 91.45 107/117 nt 8 8 X 8.8.X [1.16.5.X] null + No rearrangement found in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagaccca +3025 JY8QFUQ01DA6DQ No results +3026 JY8QFUQ01CB5ZL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +3027 JY8QFUQ01BSEF6 No results +3028 JY8QFUQ01BLIG3 No results +3029 JY8QFUQ01AO498 No results +3030 JY8QFUQ01A7MWW productive Homsap IGHV3-9*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDRKGSNWYYFENW in-frame + ctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca +3031 JY8QFUQ01AAQ5Z productive Homsap IGHV4-61*02 F 821 85.52 189/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 10 7 18 10.7.18 [1.17.38.11] CARENYYGSGSYGRAWFDYW in-frame + tctctggaggctccatcagcagtggaagctacttctggacctggatccggcagcccgccgggaaggatctggagtggattgggcgcttctacagtagtgacagtgtcgactacaacccctccctcaggggtcgagccaccatttcagcggacacgtccaagagccagttctcccttaatctgaagtctgcgaccgccgcagacacggccgtttattactgcgcgagagagaattactacggttcggggagttatgggcgggcctggtttgactactggggcccgggaatccaggtcaccgtctctgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3032 JY8QFUQ01CJCMS productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 7 7 13 7.7.13 [1.17.38.11] CARPHHNSGYSFDHW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) gtctgatttcaacgtcggtgacttgacatgcactgggtccgccagactccagacaaggggctggagtgggtggcactttttggtatgacggaaagaggaaatattatgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacaccctgtatctgcaaatggacagcctgagagccgacgacacggctacctacttttgtgcgaggcctcatcataatagtggttattcctttgaccactggggccagggaacccaggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +3033 JY8QFUQ01AEVED unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 130 55.22 74/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3034 JY8QFUQ01A1HD7 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt 95.81 206/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARADNYDSLGLKFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtaactacCtggaactggatccggcagcccccagggaagggactggagtggattgggtatatctatcacagtgggagcaccagctacaacccctccctcaggagtcgagtcaccatatcattagacacgtccaagaaccagttctccctgaaactgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggcggataattatgatagtcttgggctgaagttcgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3035 JY8QFUQ01DLCBP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3036 JY8QFUQ01BOBM0 No results +3037 JY8QFUQ01DIODI productive (see comment) Homsap IGHV1-18*01 F 845 88.37 190/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 8 8 8 8.8.8 [0.17.38.11] CARDRPNEFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'GCC' (3 nucleotides at position 8 to 10 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'AGG' (3 nucleotides at position 47 to 49 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); ctggttaGCCccctttaaatacctatggtatcacctgggtgcgacaAGGgccccctgaacacggccttgagtggatAggggtggatcagcgttcacgatggcaacacaaactatgcacagaatctccagggcagagtcaccctgaccacagacacatctacgagcacagcctacatggaactgaggggtctcagatctgacgacacggccgtttattattgtgcgagagatcgcccgaatgaattctggggccagggaaccctggtcaccgtcttctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3038 JY8QFUQ01CY80E No results +3039 JY8QFUQ01CY9YF No results +3040 JY8QFUQ01AJ3WA productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + tctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3041 JY8QFUQ01CQ4SH No results +3042 JY8QFUQ01C4GKI No results +3043 JY8QFUQ01DE5HN productive (see comment) Homsap IGHV3-48*01 F 1016 97.21 209/215 nt 96.28 207/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 7 10 8.7.10 [1.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaagggctggagtggatttcatacattagtagtagtggtatatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3044 JY8QFUQ01CWVA7 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + ctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3045 JY8QFUQ01DIGYO No results +3046 JY8QFUQ01DMW4C No results +3047 JY8QFUQ01CRVX3 unknown (see comment) Homsap IGHV3-38*01 ORF, or Homsap IGHV3-38*02 ORF or Homsap IGHV3-38*03 ORF or Homsap IGHV3-38-3*01 ORF or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 100 100.0 20/20 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found tctggattcaccgtcagtag +3048 JY8QFUQ01A8WP7 No results +3049 JY8QFUQ01DKRMQ unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 198 57.31 98/171 nt 8 8 X 8.8.X [1.17.23.X] null - No rearrangement found tctggattcaccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatacattagtagcaatggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3050 JY8QFUQ01BDI9Q No results +3051 JY8QFUQ01C39OT productive (see comment) Homsap IGHV4-4*07 F 859 88.89 192/216 nt 87.96 190/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 7 9 8.7.9 [2.17.38.11] CARDSGDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'T' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); gtctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtccaaaccagtgggagCcccccactacaacccctTccctcaagagtcgagtcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccacttttttctgtgcgagagactccggggactttgactactggggcccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3052 JY8QFUQ01DOM0M No results +3053 JY8QFUQ01BM6Z0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKCKAPGKVDWFDPW in-frame - tctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctggtaaggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3054 JY8QFUQ01CCPRB unproductive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 805 86.11 186/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtggcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3055 JY8QFUQ01CKINT No results +3056 JY8QFUQ01BME7S No results +3057 JY8QFUQ01AU45S unknown (see comment) Homsap IGHV1-NL1*01 P 90 56.79 46/81 nt 2 X X 2.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagagac +3058 JY8QFUQ01B7PED No results +3059 JY8QFUQ01BGLLH productive Homsap IGHV3-9*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKVGSQWELLRPIDYW in-frame + ctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagtggggtcccagtgggagctactaaggcccattgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccc +3060 JY8QFUQ01DCQBH No results +3061 JY8QFUQ01BX1V4 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD2-21*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSVGRYGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); cctcggggttcagcgtcaataataacttcatgacttggttccgccaggttccagggaaggggctggagtgggtctcagttatctataCaaaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccgagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtactactgtgcgagagaatttcgggcgccttctgtgggcagatatggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3062 JY8QFUQ01CKNLX No results +3063 JY8QFUQ01BRVNO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CAKKSDINNIGWHGLFDYW in-frame - ctctggatttacctttacaaattattggatgagctgggtccgccaggctccagggagggggctggagtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagctgaggacacggccttgtattactgtgcgaaaaaatcggatataaataacattggctggcacggcctatttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3064 JY8QFUQ01AS24X productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CILLYYDSRGVFSTDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggcgtgggtctcacgtattaaaagtgatggcagtggcacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagagcacgctgtttctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtatactgctttactatgatagtagaggtgtcttttcaaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3065 JY8QFUQ01CUTTF No results +3066 JY8QFUQ01CXBZV No results +3067 JY8QFUQ01DJTMW No results +3068 JY8QFUQ01C16HI No results +3069 JY8QFUQ01DG5DA No results +3070 JY8QFUQ01BARXE unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 146 53.26 98/184 nt 8 7 X 8.7.X [1.17.28.X] null + No rearrangement found tctggattcaccttcagttctcacactatgaactgggtccggcaggctccagggaaggggccggagtgggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +3071 JY8QFUQ01AV09F productive Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 740 81.82 180/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARVWVAGSRDENFDSW in-frame + Low V-REGION identity (81,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgggtgcttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgccctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3072 JY8QFUQ01AHMII No results +3073 JY8QFUQ01AF6XR No results +3074 JY8QFUQ01BLD2R No results +3075 JY8QFUQ01CU4F2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-25*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGAAV#FNSW out-of-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttaacagccatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtgcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +3076 JY8QFUQ01DHXZ0 No results +3077 JY8QFUQ01AUXE0 No results +3078 JY8QFUQ01AX27R No results +3079 JY8QFUQ01B70HN No results +3080 JY8QFUQ01CVUKJ No results +3081 JY8QFUQ01B127A unknown (see comment) Homsap IGHV3-23*05 F 100 55.45 56/101 nt 54.46 55/101 nt 7 8 X 7.8.X [1.17.X.X] null + No rearrangement found stop codons in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) tctggattcgtcttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +3082 JY8QFUQ01BW6UO No results +3083 JY8QFUQ01A24XX No results +3084 JY8QFUQ01BK2W2 No results +3085 JY8QFUQ01AXQ6G productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3086 JY8QFUQ01AY7GI productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 7 11 8.7.11 [1.17.38.11] CARVGTFNWFGPW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) tctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +3087 JY8QFUQ01BS0WR No results +3088 JY8QFUQ01B1DTR No results +3089 JY8QFUQ01AMDJ3 No results +3090 JY8QFUQ01DWKAP unproductive Homsap IGHV3-74*03 F (see comment) 842 87.16 190/218 nt 86.7 189/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] XVLEIQTVAPRTSP#W out-of-frame - Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcactttccacacctcctGggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattatttngtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +3091 JY8QFUQ01BSH4W No results +3092 JY8QFUQ01DKKW7 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 449 72.47 129/178 nt 8 8 X 8.8.X [1.17.25.X] null - No rearrangement found Low V-REGION identity (72,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3093 JY8QFUQ01DOWWF No results +3094 JY8QFUQ01BVC70 No results +3095 JY8QFUQ01CHHAT No results +3096 JY8QFUQ01BAK7Q No results +3097 JY8QFUQ01B0F0I No results +3098 JY8QFUQ01COB21 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARLRSFGDYPLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 99 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggggaagggactggtgtgggtctcacatattaatactgatggtactaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3099 JY8QFUQ01DE3I7 productive Homsap IGHV4-61*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERSISIGGAREFDSW in-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tcactggtggccccatgggcagtagtttatacttctggaattgggtccgacagcccgccgggaagagactggagtggatcggacgtgtttatgatgatgggagtacccgctacaatccctccctcaggggtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaggttgagttttgtgaccgccgcagacacggcccgttattactgtgcgagagaacggagtatttcgattggcggagcgagagaatttgactcttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3100 JY8QFUQ01DAOHD unknown (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcacatttagtaactactggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctcttccaccaagggcccatccgtcttccccctggcgccctgctccaggcagcacctccgagagcacagccgcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3101 JY8QFUQ01DG09I No results +3102 JY8QFUQ01B4ZK0 No results +3103 JY8QFUQ01AR168 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 2 8 7 12 8.7.12 [1.17.38.11] CVRHRRLELLPDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcaataattacttctggacctggatccgccagTcccccagggaaggggccggagtggattggggaaatcaatcatagtggtagcaccaactacaatccgtccctcaagagtcgagtcaccatctcaatagacacgtccaagatccagttctccctgcagctgagctctgtgaccgccgcggacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +3104 JY8QFUQ01CGD2D productive Homsap IGHV1-58*02 F 930 92.99 199/214 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD3-9*01 F 1 8 8 14 8.8.14 [0.17.38.11] CAAVLAGWGFYYFDFW in-frame - tggattcacctttaaaagttctgctatacagtgggtgcgacaggcccgtggacaacgccttgagtggataggatggaccgccgttggcagcggtaacacagactacgcacagaagttccaggaaagagtcaccattacgagggacatgtccacaagcacagtctacatggagatgatcaacctgggatccgaggacacggccgtgtattactgtgcggcagtcttggccggctggggattctattacttcgatttctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3105 JY8QFUQ01BJIX5 unproductive Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDGPPYLYGSHGNSFDQ## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggcccagggaaccctagtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgggaactcag +3106 JY8QFUQ01DV19Z unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F or Homsap IGHV1-69*01 F or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F 86 57.53 42/73 nt 56.16 41/73 nt X X X X.X.X [24.X.X.X] null - No rearrangement found in FR1-IMGT, from codon 7 of V-REGION: 3 nucleotides (from position 90 in the user submitted sequence), (do not cause frameshift) agttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgctctcggaggtgctcctggagcagggcgccagggggaagaccgatgggcccttggtggaggtgacgaagccaccagaga +3107 JY8QFUQ01DI014 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CANEVGYCSGGG in-frame + ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccgaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +3108 JY8QFUQ01DOBZY productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); ctccggattcaccGtttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3109 JY8QFUQ01BQ9WT No results +3110 JY8QFUQ01AZQ2B productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 662 77.98 170/218 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIVREGLDHW in-frame + Low V-REGION identity (77,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tgtctggtggctccatcgccacttatcattggtggaattgggtccgccagacccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3111 JY8QFUQ01CF936 unproductive Homsap IGHV3-7*01 F 975 95.33 204/214 nt 94.86 203/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.37.11] CAKGVVTA#LDYW out-of-frame + in FR3-IMGT, from codon 66 of V-REGION: 3 nucleotides (from position 104 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaatttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +3112 JY8QFUQ01CGZG3 No results +3113 JY8QFUQ01AICJL No results +3114 JY8QFUQ01B3B91 No results +3115 JY8QFUQ01ACBJX unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*04 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*03 F or Homsap IGHV3-66*04 F (see comment) 263 72.82 75/103 nt 71.84 74/103 nt 8 7 X 8.7.X [1.16.1.X] null + No rearrangement found Low V-REGION identity (72,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 31 in the user submitted sequence), (cause frameshift) tctggcttcaccgtcaataacaactacatggctgggtccgccaggctccagggaaggggctggagtgggtcatcgcctgcctggtccagggcttcttcctcca +3116 JY8QFUQ01AWJ7L No results +3117 JY8QFUQ01BWBZA No results +3118 JY8QFUQ01DGGFP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctagattcaccttcagtagctataatatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +3119 JY8QFUQ01AQQ9J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDREDSSGYYFFRDGFDIW in-frame + ctctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctccggtattggtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagatcgtgaagatagtagtggttattacttcttccgtgatggttttgatatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3120 JY8QFUQ01BJLT6 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 737 82.79 178/215 nt 82.33 177/215 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.37.11] CARIWDSWSGAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) tctggattcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgagggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagagcttcttccccca +3121 JY8QFUQ01DNCVB No results +3122 JY8QFUQ01BX1Y8 No results +3123 JY8QFUQ01DFBZM productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVKDISRSGCFEYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtaCtaaaaagctacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag +3124 JY8QFUQ01B0LE9 No results +3125 JY8QFUQ01COKDY No results +3126 JY8QFUQ01CAZ5U No results +3127 JY8QFUQ01A8OUJ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3128 JY8QFUQ01DDPR3 productive (see comment) Homsap IGHV3-9*01 F 986 94.95 207/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [2.16.38.11] CAKSGTYSSSSGHFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gcctctggattcaactttaataaGttatgccatgcactggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3129 JY8QFUQ01B6NV3 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 160 80.0 40/50 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDRLNGDYTFGA#FDLW out-of-frame + stop codons Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) ctctaaatttgacttcagtgactatggcatgaactgggtccgccaggttccagggaaggggctggagtgggtctcctacataagtcgtctgagtcgccaaatatatgtcgctgacccagtgaagggccgattcaacatctccagagacaacgccaagaattcactgtatctgcaaatgaacaacttgcgggtcgaagacacggctgtgtatttttgtgccaaagatcgcctgaacggtgactacacattcggcgcattttgatctgtggggcccagggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca +3130 JY8QFUQ01AVE52 No results +3131 JY8QFUQ01CG3T2 unknown (see comment) Homsap IGHV1-8*01 F, or Homsap IGHV1-8*02 F (see comment) 246 84.06 58/69 nt 8 X X 8.X.X [0.14.X.X] null + No rearrangement found Low V-REGION identity (84,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatataccttcaccagatatgatatcaattgggtgcgacaggccactggacaagggcttcttccccc +3132 JY8QFUQ01CTRTT No results +3133 JY8QFUQ01A66X0 No results +3134 JY8QFUQ01AQ3MO No results +3135 JY8QFUQ01B7SCL No results +3136 JY8QFUQ01BLUZD unproductive (see comment) Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARVIPGRGK##AFDVW out-of-frame + stop codons ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggcaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +3137 JY8QFUQ01AU8LW No results +3138 JY8QFUQ01CP1IY No results +3139 JY8QFUQ01B80QR unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 619 93.62 132/141 nt 92.2 130/141 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 7 1 X 7.1.X [1.X.37.11] CVMRFGWSERF#W out-of-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01B80QR ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 38 of V-REGION: 75 nucleotides (from position 26 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttatgcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3140 JY8QFUQ01C7HP4 No results +3141 JY8QFUQ01ADZ41 No results +3142 JY8QFUQ01BAYGY No results +3143 JY8QFUQ01AYQGT productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +3144 JY8QFUQ01CNYI4 No results +3145 JY8QFUQ01BXVRF No results +3146 JY8QFUQ01CRHFL No results +3147 JY8QFUQ01AH5QJ productive Homsap IGHV3-64*02 F 953 93.95 202/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVTCGDYSYEYW in-frame - ctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3148 JY8QFUQ01BLQS0 No results +3149 JY8QFUQ01A7LAD No results +3150 JY8QFUQ01ALUCO unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 853 89.2 190/213 nt Homsap IGHJ3*02 F (see comment) 187 86.0 43/50 nt Homsap IGHD6-13*01 F 2 8 7 X 8.7.X [1.17.38.11] CARPTYSSGRD#AFDTW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) tatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggactgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3151 JY8QFUQ01AO1ZP No results +3152 JY8QFUQ01DLDAU No results +3153 JY8QFUQ01DKHL3 productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 999 93.81 212/226 nt 92.92 210/226 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 10 9 19 10.9.19 [1.16.38.11] CARASRRDRQSDRNYYELDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'A' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 63 in the user submitted sequence), (cause frameshift) cctccggggacagtgtctctagcaacagtgccacAttggaactggatcaggcagtccccaacggaggccttgagtggctgggaaggacatcctacaggtccaaatggtatagtgattatgcggtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcaattgaactccgttagtcccgaggacacggctgtgtattactgtgcaagagcttccagacgcgatcgtcagtctgatcggaactactatgagctggacttctggggccagggaatcttggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3154 JY8QFUQ01AP4EW No results +3155 JY8QFUQ01DBAHL No results +3156 JY8QFUQ01C4HCZ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 851 88.07 192/218 nt 87.16 190/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 7 8 17 7.8.17 [2.16.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) agcctctggattcagtttagtacacatggcatgaactgggtccgccaggctccagggaagggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3157 JY8QFUQ01BPIK6 unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3158 JY8QFUQ01AISKV No results +3159 JY8QFUQ01BASM2 unknown (see comment) Homsap IGHV3-23*05 F 97 54.81 57/104 nt 8 8 X 8.8.X [1.17.X.X] null + No rearrangement found stop codons ctctggattcgtctttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3160 JY8QFUQ01CMQFU No results +3161 JY8QFUQ01BWGBV No results +3162 JY8QFUQ01B2BAU No results +3163 JY8QFUQ01DGYOV No results +3164 JY8QFUQ01A0QXW productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt 99.53 213/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagtagttactactggagctggatccggcagAcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3165 JY8QFUQ01AX2ZP No results +3166 JY8QFUQ01DS6X3 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 977 94.5 206/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-13*01 F 3 8 7 12 8.7.12 [2.17.38.11] CARGVGQQLPPLDW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 27 of V-REGION: 'C' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'CC' (2 nucleotides at position 27 to 28 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); ctgtctctCgctgcctccatcaatagCCtttttactggagctggatccggcagcccccagggaagggactggagtggattggatatatctaCtgatagtgggagcaccaactacaAacccctccctcaagagtcgagtcaccatatctatagacacgtccaagaaccagttctccctgaggctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagaggggtggggcagcaactgccccccttagactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3167 JY8QFUQ01CEPQD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccaggaagctttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3168 JY8QFUQ01BXDO8 No results +3169 JY8QFUQ01C04M5 No results +3170 JY8QFUQ01BQRTA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 498 83.69 118/141 nt 8 8 X 8.8.X [2.17.12.X] null - No rearrangement found Low V-REGION identity (83,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactca +3171 JY8QFUQ01DMVX2 productive (see comment) Homsap IGHV3-7*01 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.16.38.11] CARDPYNGGGYGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 77 in the user submitted sequence), (cause frameshift) tctggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccacataaagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgcaaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagacccctataatggtggtggttatggtgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3172 JY8QFUQ01CAM4X No results +3173 JY8QFUQ01DO7TR unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +3174 JY8QFUQ01CF2XO unproductive (see comment) Homsap IGHV4-4*07 F 854 88.84 191/215 nt 87.91 189/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcaatggcatttaCctggagttggattcgacaatccgccggaaagggactggagtggattgggcgcatccataccagtgggagcaccaactacaaccCcctccctcaaaagtcgagtcaccatgtcgatagacacgtccaagaaccagttctccctaaggttgacctctgtgaccgccgcggacacggccatttattactgtgcaaaagacatacaggatgaggataattactgggggccagggagcccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3175 JY8QFUQ01B6D3V productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccgag +3176 JY8QFUQ01DHZV7 unproductive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 8 X 8.8.X [0.17.38.11] CARGFTV#HFDSW out-of-frame - tggatacaccttcagcgactactacatacactggctgcgacaggcccctggacaacgacttgagtggatgggatggctgaaccctaataatggtgacacagcttatggccagagctttcagggccgggtcaccatgaccagggacacgtccgtcagcacagtgtacgtggaggtgaggaggctgagatctgacgacacagccctttatttctgtgcgagaggctttacggtgaccactttgactcctggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3177 JY8QFUQ01BKMU4 No results +3178 JY8QFUQ01C1OCG No results +3179 JY8QFUQ01AXBZZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +3180 JY8QFUQ01DU14G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDVSTRITMRVVVPALDYW in-frame + gtctggattcacgtttagaaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattagtgataatggtgacagcatattccacgcagactccgtgaagggccggttcaccatcaccagagacaactctaagaacatcctgtatctgcacatgaacagcctgagagccgaggactcggccgtatattactgtgcgaaggatgtttccacgcgtattactatgagagttgtggtgccagcccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +3181 JY8QFUQ01B2IY1 unproductive Homsap IGHV4-4*07 F (see comment) 1016 97.21 209/215 nt Homsap IGHJ2*01 F (see comment) 94 64.15 34/53 nt Homsap IGHD6-19*01 F 3 10 7 X 10.7.X [1.17.38.11] CARDFSNRGWYFDL# out-of-frame - The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01B2IY1 ; 8 AA in Homsap_IGHV4-4*07) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) tctctggtgactccatttccagtactagttattactggggctgggtccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctgggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3182 JY8QFUQ01BM5OL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 766 87.06 175/201 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 4 8 14 4.8.14 [X.17.38.11] CAKEEGATGVYYVDHW in-frame - accacctccgccatggcctgggtccgccaggttccagggaaggagctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3183 JY8QFUQ01BQWVC unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 694 81.43 171/210 nt 8 7 X 8.7.X [X.17.38.X] null + No rearrangement found Low V-REGION identity (81,43% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag +3184 JY8QFUQ01DJP57 No results +3185 JY8QFUQ01DLJ14 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 829 86.76 190/219 nt 86.3 189/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 7 8 8 7.8.8 [2.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 30 in the user submitted sequence), (cause frameshift) gcctctggggttcgccgtcagtagcaagtcatgagttgggtccgccaggctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +3186 JY8QFUQ01C6DJA unproductive (see comment) Homsap IGHV3-7*01 F (see comment) 414 65.44 142/217 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt Homsap IGHD7-27*01 F 3 8 8 2 8.8.2 [1.17.38.6] NR*R in-frame + stop codons Low V-REGION identity (65,44% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaagcgtactatgcggactctgtgaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3187 JY8QFUQ01CHUV9 productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3188 JY8QFUQ01BVKTT unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 428 77.24 112/145 nt 8 8 X 8.8.X [1.17.14.X] null + No rearrangement found Low V-REGION identity (77,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctacgtggtcgtcgcatgcctggtccagggcttcttcccc +3189 JY8QFUQ01BGC9V No results +3190 JY8QFUQ01COBGR unproductive Homsap IGHV3-33*03 F 927 92.17 200/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGGSSGWFGRCGRL# out-of-frame + gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggcagcagtggctggtttggacgttgtggacgtctggggccaagggtaccacggtcaccgtcgcctcagcctccaccaagggccctatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3191 JY8QFUQ01DTF77 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 922 92.13 199/216 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + tctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +3192 JY8QFUQ01CYJU0 No results +3193 JY8QFUQ01AP21C productive (see comment) Homsap IGHV1-18*01 F 876 90.19 193/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD1-14*01 ORF 3 8 8 8 8.8.8 [0.17.38.11] CARDRPNEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 104 of V-REGION: 'T' (1 nucleotides at position 213 to 213 in the user submitted sequence), (cause frameshift); tggttacccctttaatacctatggtatcacctgggtgcgacaggCcccctggacacggccttgagtggatggggtggatcagcgttcacgatggcaacacaaactatgcacagaatctccagggcagagtcaccctgaccacagacacatctacgagcacagcctacatggaactgaggggtctcagatctgacgacacggccgtttattatTtgtgcgagagatcgcccgaatgaattctggggccagggaaccctggtcaccgtcttcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3194 JY8QFUQ01AAP53 No results +3195 JY8QFUQ01BAO9A productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 7 18 8.7.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3196 JY8QFUQ01B4NFZ unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 X 8.7.X [4.17.38.11] CARGGPIL** (see Functionality comment) out-of-frame + stop codons, IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +3197 JY8QFUQ01A2KWU unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F (see comment) 567 73.27 159/217 nt Homsap IGHJ2*01 F 31 64.71 11/17 nt Homsap IGHD5-18*01 F 3 8 8 X 8.8.X [1.17.38.5] PV## out-of-frame + Low V-REGION identity (73,27% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +3198 JY8QFUQ01BCEXD No results +3199 JY8QFUQ01CYZLO No results +3200 JY8QFUQ01DV3LY productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 2 8 7 16 8.7.16 [2.17.38.11] CARVDFYGSSKYKGFDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); gtctctggtaactccatcacagattattactggagctggctccggcagtctccagggaagggactggagtggattggaaatgtcCttttacagtgggagagccaactacaacccctccctcaagagtcgagtcaccatatcagtagccacgtccaggaaccagttctccctgaagctcaggtctgtgaccactgcggacacggccatatattattgtgcgagagttgatttctatggttcgagtaaatataaggggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3201 JY8QFUQ01CJWCW No results +3202 JY8QFUQ01B9JK5 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 88 51.91 68/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +3203 JY8QFUQ01BJSP8 unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F (see comment) 676 80.38 168/209 nt 8 8 X 8.8.X [1.17.35.X] null + No rearrangement found Low V-REGION identity (80,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagcacgaccataggctacgcagactctgtgaggggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggatagcctgcctggtccagggcttcttcccca +3204 JY8QFUQ01DSDCP unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-3*02 F 2 8 8 X 8.8.X [1.17.38.11] CATYGRFSFSPLDY## out-of-frame - gtctggattcgacttcagtagttatggcttccattgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctccccttgactactgggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3205 JY8QFUQ01B2EAY No results +3206 JY8QFUQ01BQM0J No results +3207 JY8QFUQ01CD3DH productive (see comment) Homsap IGHV3-7*03 F 886 90.28 195/216 nt 89.35 193/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 8 16 8.8.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); tctagattcacctttaatggttaCtgggatgagttgggtccgccaggctccaggaaAaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3208 JY8QFUQ01BGNVA productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt 84.79 184/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-10*02 F 2 8 8 13 8.8.13 [1.17.37.11] CAKERDNNVLPVDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 123 in the user submitted sequence), (cause frameshift) cctctggattcagcttcaatagttatactttgagttgggtccgccaggctccagggaaggggctggagtgggtctcagctatcagtggaacaggtgaaacaaccttctacgcggactccgtgagggccggttcaccgtctccagagacaatttcaagaatactctgtacttgcaattgagcgacctgagagccgaagacacggccgtctattactgtgcgaaggagagagataacaatgttctgcccgttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +3209 JY8QFUQ01BCL4D No results +3210 JY8QFUQ01BT6IL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 99.54 216/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 84 62.75 32/51 nt 8 8 16 8.8.16 [1.17.38.11] CAYGGMTRWLAHQFDYWG (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgcgcatatgggggcatgacgcggtggctggctcaccagtttgactactggggcccaggggaacccctggtcaccgtctcctcagggagtgcatccgcccccaaccctt +3211 JY8QFUQ01CE5ND productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF (see comment) 887 91.87 192/209 nt 90.43 189/209 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [0.15.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CE5ND ; 8 AA in Homsap_IGHV3-20*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 55 of V-REGION: 4 nucleotides (from position 74 in the user submitted sequence), (cause frameshift) ctggattcacctttggttattatggcatgagctgggtccgccaagctccagggagggcgtggagtggtctctgtatatcggatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3212 JY8QFUQ01DAOOD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaacccctggtcaccgtctcctcagctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3213 JY8QFUQ01CGF4V productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3214 JY8QFUQ01CNJJ3 productive Homsap IGHV4-59*08 F 1061 99.53 214/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-8*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARGYCSNAVCYQIMNW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggccgtgtattactgtgcgagaggatattgttctaatgctgtatgctatcaaatcatgaactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggcctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +3215 JY8QFUQ01AQVWM No results +3216 JY8QFUQ01DJRT2 productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +3217 JY8QFUQ01BOVP9 No results +3218 JY8QFUQ01BXC3X unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 193 93.18 41/44 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found tctggattcaccttcagcaagtatgccatgagctgggtccgcca +3219 JY8QFUQ01BJMU2 No results +3220 JY8QFUQ01BJQK4 No results +3221 JY8QFUQ01BE7WZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + tctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3222 JY8QFUQ01B4PWC productive Homsap IGHV3-7*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3223 JY8QFUQ01AZ8A1 unproductive (see comment) Homsap IGHV4-61*02 F (see comment) 731 81.45 180/221 nt Homsap IGHJ4*02 F (see comment) 114 70.83 34/48 nt Homsap IGHD3-16*02 F 2 10 7 X 10.7.X [1.17.38.11] CARERAASSH*RVRELDF## out-of-frame + stop codons Low V-REGION identity (81,45% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) tctctggtgactccattaccagtggtttttactactggaattggatcagacagcccgccgggaggggactggagtggatcggacgtgtctatattactgggagtgtcaactacagtccatccctcgaacacagagtcagtatatctctagacacgtccaagaggcaattcttcttgaggttggtctctgtgaccgccgcagacacggccgtgtattactgtgcgagagagcgggctgccagttcgcattgacgagtgagagaacttgacttctggggccagggggaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3224 JY8QFUQ01C02Y6 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3225 JY8QFUQ01DEMQ9 unproductive (see comment) Homsap IGHV3-30*01 F 927 92.17 200/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CVKN*PVLGHNRALP*LL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacgttcaacatttatggtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaattgacctgtcttggggcacaatagagcactaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtagtcatcgcctgcctggtccagggcttcttcccccag +3226 JY8QFUQ01DS8S2 productive Homsap IGHV3-48*03 F 865 88.58 194/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDKGWSGYGMDVW in-frame - gcctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3227 JY8QFUQ01A58CS productive Homsap IGHV3-7*03 F 900 90.78 197/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame + ctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccgattcaccatctccagagacaatgcccagaactcactgtttctgcaaatgaacagcctgcgagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagnacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3228 JY8QFUQ01DNNPU unproductive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*03 F (see comment) 387 64.52 140/217 nt 63.59 138/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [2.17.38.11] CTRELRVAAARDGVDIW in-frame - stop codons Low V-REGION identity (64,52% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'ATG' (3 nucleotides at position 61 to 63 in the user submitted sequence), (do not cause frameshift); gcctctggattcaccgtcagtaccaaggtTcatgagctgggtccgccaggctccagggcaATGggggctggagtgggtctcagtaactttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3229 JY8QFUQ01DINN6 No results +3230 JY8QFUQ01CO8CX No results +3231 JY8QFUQ01AOHOF productive Homsap IGHV4-59*03 F 899 91.16 196/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-23*01 ORF 3 8 7 9 8.7.9 [1.17.38.11] CARGVTPEGYW in-frame + tctcgggtgactccatcactcctaactcctggagctggatccggcagcccccagggaagggactggagtggattggttatatctattacagtggaatcaccaagcacaacccctccctcaagagtcgagtcgccatttcagtagacacgtccaagaaccaattttccctgaggctgagttctgtgaccgctgcggacacggccgtttatttctgtgcgaggggggtcactccggagggctactggggccagggaatcttagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +3232 JY8QFUQ01AH1TD No results +3233 JY8QFUQ01ASY07 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 886 89.86 195/217 nt 88.94 193/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD4-11*01 ORF 2 8 8 11 8.8.11 [2.16.37.11] CVKAGDISWYDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 209 in the user submitted sequence), (cause frameshift) gcctctggattcacctttagcagctacaccatgggctgggtccgccaggctccagggaagggctggagtgggtctcagatatcaataggagcggtggtacgacatactacgtagactccgtgaggggccggttcaccatttccngagacaactccaaaaacacgctgtatctgcagatggacagcctgagagtcgaggacacggccatttttactgtgtgaaagccggcgacatcagttggtacgactactggggccagggagccctggtcaccgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3234 JY8QFUQ01B02NC No results +3235 JY8QFUQ01DI29B No results +3236 JY8QFUQ01DFAXC productive (see comment) Homsap IGHV3-9*02 F 838 87.21 191/219 nt 86.76 190/219 nt Homsap IGHJ2*01 F (see comment) 157 77.36 41/53 nt Homsap IGHD4-11*01 ORF 3 8 8 17 8.8.17 [2.16.38.11] CARAPSVTFSGQGHYYDLW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) aggcactggattcagctctgagaattatgccatgcactgggtccggcagcctccaggaagggcctagagtgggtctcacacatcagttggaatggcgaaggcatcgactacgcggactcagtgaagggccgattcaccgtctccagagacaacggcaagaattccctgtatttgcaaatgaacagtctgacaactgacgacacggccttgtattactgtgcaagagccccttcagtcacattcagcgggcaggggcactactatgatctctggggccgtggcaccctggtcgtggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3237 JY8QFUQ01A6G0B unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 302 96.88 62/64 nt 8 X X 8.X.X [1.12.X.X] null - No rearrangement found tctggattcaccttcagcagctatagaatgaactgggtccgccaggctccagggaaggggctgg +3238 JY8QFUQ01BOYGD No results +3239 JY8QFUQ01C2U0I No results +3240 JY8QFUQ01BF4BW No results +3241 JY8QFUQ01DN8Y7 unproductive Homsap IGHV3-7*03 F (see comment) 540 71.89 156/217 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt Homsap IGHD5-18*01 F 3 8 8 X 8.8.X [1.17.38.6] PV## out-of-frame + Low V-REGION identity (71,89% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactccgtgaagggccgattcaccatctccagagacaattccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3242 JY8QFUQ01DRIZW No results +3243 JY8QFUQ01C8XFG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 892 89.95 197/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - gcctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3244 JY8QFUQ01CLCPQ No results +3245 JY8QFUQ01DAFCH No results +3246 JY8QFUQ01BLMEC No results +3247 JY8QFUQ01DRSFS unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 945 93.09 202/217 nt 92.63 201/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); ctctggattcacctttgatgattttggcatgagatgggtccgccaagtcccagggaaggggctacagtgggtctctgggattaattGggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaaggggcaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtccatcgcctgcctggtccagggcttcttcccccg +3248 JY8QFUQ01AXBY3 No results +3249 JY8QFUQ01CFQIN No results +3250 JY8QFUQ01BUZB4 unproductive Homsap IGHV3-66*02 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 1 8 7 X 8.7.X [1.17.38.11] CVGRSSKGITIS#YW out-of-frame + ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtggggagatcgtcaaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +3251 JY8QFUQ01AHBZ8 No results +3252 JY8QFUQ01DV3Q9 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame + cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3253 JY8QFUQ01BK1U9 No results +3254 JY8QFUQ01CELX5 No results +3255 JY8QFUQ01A2ZLE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 883 89.5 196/219 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - ggctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcatcgtttcctcagcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3256 JY8QFUQ01BWZOD No results +3257 JY8QFUQ01DCAPL productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3258 JY8QFUQ01BJI1W No results +3259 JY8QFUQ01C70X6 productive Homsap IGHV3-48*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 2 8 8 9 8.8.9 [1.17.38.11] CAWGPNGADYW in-frame + ctctggattcaccttcggtaactcaaccatgaactgggtccgccaggctccagggaaggggctggaatggctgtcatatcttagtagtggtggtgatgtcaaatactacgcaggctctctgaagggccgattcaccatctccagagacagtgccaggaactcactgtatctgcaaatgaacagcctgacagacgaggacacggccgtatattactgtgcatgggggcccaacggcgccgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +3260 JY8QFUQ01CGYIW No results +3261 JY8QFUQ01B1HQ0 No results +3262 JY8QFUQ01CLXYH unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 746 82.79 178/215 nt 8 8 X 8.8.X [0.17.38.X] null - No rearrangement found Low V-REGION identity (82,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3263 JY8QFUQ01DXDU5 productive Homsap IGHV4-39*02 F (see comment) 771 83.64 184/220 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD2-15*01 F 2 10 7 19 10.7.19 [1.17.38.11] CARHLTNSDVVHHFYSGVDVW in-frame + Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggtgcctccatcagtaatgataattatttctgggcctgggtccgccagtccccagggaagggtctgcagtggattggcagtatgtattatagtgggggcaccttttacgacccgtccctcaagggtcgaatcaagttgtccgttgacgtgtcgaagagccacttcctcctgaacctgacctctgcgaccgccgcagacacggctgtctattactgtgcgaggcatttgaccaactcagatgtggtccatcacttctactccggagtagacgtctggggcctcgggaccacggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3264 JY8QFUQ01CXO2O unknown (see comment) Homsap IGHV3-48*01 F 1017 96.77 210/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtggctactgggggccagggtaaccccgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +3265 JY8QFUQ01BWUVE No results +3266 JY8QFUQ01CL3UU productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggttcagggcttcttccccca +3267 JY8QFUQ01C8IAO No results +3268 JY8QFUQ01DV057 productive Homsap IGHV3-48*04 F 991 94.98 208/219 nt Homsap IGHJ4*02 F (see comment) 231 97.92 47/48 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CARDAGGSGWYLYYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcaccttcagtagttataccatgcactgggtccgccaggctccagggaaggggctggaatgggtctcatccattagtagtagtagtactaccatatactacgcagactctgtgaagtgccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacggcctgagagccgaggacacggctgtttattcctgtgcgagagatgcggggggcagtggctggtacctttactactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3269 JY8QFUQ01AIC3H productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctgacaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3270 JY8QFUQ01CRFZZ No results +3271 JY8QFUQ01A6ZI7 productive Homsap IGHV3-30*19 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKSPSQVGYYLDCW in-frame + tctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccggcaaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcaccatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3272 JY8QFUQ01DRGJF No results +3273 JY8QFUQ01B5WDT No results +3274 JY8QFUQ01BKKCI unproductive Homsap IGHV3-48*01 F 859 88.89 192/216 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARASTFYYDGSGYRD#FDIW out-of-frame + tctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgttttgatatatggggccaagggacaatggtcaccgtctcctcagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag +3275 JY8QFUQ01A56F5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKDMGGDYYIFHYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'C' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); ttctggattctcctttagcaactatgccctgggCctgggtccgccaggctccagggaaggGggctggagtgggtctcaattgttagtggaagtggtactggcacaggccacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggatatgggtggcgactattacatctttcactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3276 JY8QFUQ01AJL7I productive Homsap IGHV4-61*02 F 1005 95.45 210/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*02 F 2 10 7 15 10.7.15 [1.17.38.11] CARAGKQDFWSGYSDDW in-frame + ctctggtggctccatcggcagtggtagttattactggagctggatccggcagcccgccgggaagggactggaataccttgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgctgacacggccatttattactgtgcgagagcggggaaacaggatttttggagtggttattctgacgactggggccagggaaccctggtcatagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3277 JY8QFUQ01CXEVJ productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +3278 JY8QFUQ01CU80D unproductive Homsap IGHV3-48*03 F 810 85.71 186/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDPREGA#FFDYW out-of-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccagattccagggaaggggctggagtgggtagggtacattagtagtactgggaataccatatattacgcagactctgtgaggggccgattcaccatctcccgcgacattgccgaaaattcactgtatctgcaaatgaatagcctgacacccgacgacacggctgtctattactgcgcgagagatccccgagagggggcaccttctttgactactggggccggggaaccctggtcaccgtctcctctgcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3279 JY8QFUQ01AZJ1G unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSDFYSTGPL# out-of-frame + ctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggcccactggggcccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa +3280 JY8QFUQ01AEQU4 productive (see comment) Homsap IGHV4-39*03 F 902 90.0 198/220 nt 89.55 197/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'TT' (2 nucleotides at position 71 to 72 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaacagtagaaattattattggggctggatccgccagccccccagggaagggttTTggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +3281 JY8QFUQ01A0TRH No results +3282 JY8QFUQ01A1D4S No results +3283 JY8QFUQ01AO2QZ No results +3284 JY8QFUQ01BE4X5 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 976 92.89 209/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGDYYDSGGLDYW in-frame - ctccgggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtgattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3285 JY8QFUQ01BCUCE unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 89 58.57 41/70 nt 8 X X 8.X.X [1.14.X.X] null + No rearrangement found ctctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttcccc +3286 JY8QFUQ01AXDJ6 No results +3287 JY8QFUQ01CKBC1 No results +3288 JY8QFUQ01BTHHB No results +3289 JY8QFUQ01DN5IU unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 193 93.18 41/44 nt 8 X X 8.X.X [1.5.X.X] null - No rearrangement found ctctggattcaccttcagcaagtatgccatgagctgggtccgcc +3290 JY8QFUQ01CH3N0 No results +3291 JY8QFUQ01A764V No results +3292 JY8QFUQ01BDU33 unknown (see comment) Homsap IGHV3-7*02 F (see comment) 226 57.59 110/191 nt 57.07 109/191 nt 8 8 X 8.8.X [1.16.30.X] null + No rearrangement found stop codons Low V-REGION identity (57,59% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaagggctggagtgggtggccaacataatgccagatggagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatggcaacgtggtcgtcgcatgcctggtccagggcttcttcccca +3293 JY8QFUQ01A38XN No results +3294 JY8QFUQ01DU0GI productive (see comment) Homsap IGHV3-48*02 F 781 85.45 182/213 nt 84.04 179/213 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD6-13*01 F 1 7 7 13 7.7.13 [1.17.37.11] CATARKYTINWRDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'GGC' (3 nucleotides at position 88 to 90 in the user submitted sequence), (do not cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 71 of V-REGION: 1 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) tctctggattgacttcaatagctttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtggcgtacatcagttgGGCcagtacaaacatattccacgcagagtctttcagggccgattcaccatctccagagacgatgcgaaggagtcactctatttgcaaatggaccgcctgacacacgacgacacggcagtatattactgtgcgacggcccgaaaatataccatcaattggagggactattggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3295 JY8QFUQ01CZP1B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3296 JY8QFUQ01DFS61 unproductive Homsap IGHV3-48*02 F 976 94.91 205/216 nt Homsap IGHJ6*02 F (see comment) 224 83.87 52/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGEGDPFFP##YSGLDVW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ5*02 (shorter alignment but highest percentage of identity) tctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgttttttccacnactactccggtttggacgtctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3297 JY8QFUQ01BB1ZL productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARPFSGRWCFDLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattCaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +3298 JY8QFUQ01CBDNC unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 709 85.13 166/195 nt 84.62 165/195 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) tgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcagg +3299 JY8QFUQ01CX1TO productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 639 93.79 136/145 nt 93.1 135/145 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 1 8 X 12 8.X.12 [1.8.31.11] CARRDVGLHAFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 72 nucleotides (from position 53 in the user submitted sequence), (do not cause frameshift) ttctggatccaattttaactacgactggatcggctgggtgcgccagatgcccggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgcttttgatctgtggggccaggggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +3300 JY8QFUQ01B71SX No results +3301 JY8QFUQ01B1AO1 No results +3302 JY8QFUQ01BLTJO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 815 86.24 188/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD2-8*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKGASTAVMVSGTDCYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattccccttcagcacctatcccatgagctgggtccgccaggctccagggaggggactggagtgggtcgcaactataagtggtggaggttatagtatatatgacgcagactccgtgaagggcaggttcaccatctccagagacaactccaagaccaccttgtttctggaaatgaaaagtctgagagtcgatgatacggccgtctattactgtgcgaaaggggcctcgactgcagtaatggtgtctggaacagattgttacggtttggacgtctggggccacgggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3303 JY8QFUQ01DNOF4 No results +3304 JY8QFUQ01AW13H productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - cctctggattccccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaggggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3305 JY8QFUQ01BWDIP productive (see comment) Homsap IGHV1-24*01 F 957 94.39 202/214 nt 93.93 201/214 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD3-16*01 F 2 8 8 11 8.8.11 [0.17.38.11] CVGDVGWGYPQGW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); cggatacaccctcaatgaattatccatgcactgggtgcgacagactcctggaaaagggcttgagtcgatgggcggAttttgatcctgaatatggtaaaacaatctacgcgcagaagttccagggcagagtcaccatgaccgaggacacatctgcagacacagcctacatggagttgagaagcctgagatttgaggacacggccgtgtattattgtgtcggagatgtcggctggggatacccccaaggctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3306 JY8QFUQ01DV0CS productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1038 98.6 211/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3307 JY8QFUQ01CYTUQ No results +3308 JY8QFUQ01DMRDJ unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 123 68.42 39/57 nt 8 X X 8.X.X [1.9.X.X] null - No rearrangement found cctccggattcacctttagtagtttctggatgcactgggtccagggcttcttcccca +3309 JY8QFUQ01A0APK unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 121 54.48 73/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcagatttagcagctatggcatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3310 JY8QFUQ01AIPBE No results +3311 JY8QFUQ01CAL51 No results +3312 JY8QFUQ01B27X3 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [2.16.38.11] CARDTLEVVSNMDDAFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3313 JY8QFUQ01DH22E No results +3314 JY8QFUQ01DR9HF unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3315 JY8QFUQ01BSPXT productive Homsap IGHV3-7*01 F 837 87.56 190/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CGRDERGADLPNDSW in-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagccccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctggggcctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3316 JY8QFUQ01CH3RZ unproductive (see comment) Homsap IGHV4-4*07 F 885 90.65 194/214 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD6-19*01 F 2 8 7 18 8.7.18 [1.17.38.11] CTKM*GHWAVTRTGDTLIIW in-frame + stop codons ctctggtgactccatcaatactttctactggagctgggtccggcagtccgccgggaagggactggagtggattgggcgtatctattccagtggggacaccaactacaacccctccctcaggagtcgagtcaccatgtcaatagacacgtccaggagtcagttctccctgaggctgacgtctgtgagcgccgcggacacggccatatattactgtacaaagatgtagggccactgggcagtgactcgtactggggatactcttattatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +3317 JY8QFUQ01B6JM9 No results +3318 JY8QFUQ01APNUG productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +3319 JY8QFUQ01ARXPV No results +3320 JY8QFUQ01AWH7M productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3321 JY8QFUQ01ARM46 No results +3322 JY8QFUQ01AHRGK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.37.11] CARGGLEPVDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 105 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaactacgcggactccgtgaatggccaattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +3323 JY8QFUQ01BF675 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3324 JY8QFUQ01DBSK6 unproductive Homsap IGHV4-59*02 F 894 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*01 F 2 8 7 X 8.7.X [1.17.38.11] CARGGSGGALLESDPG#W out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'GAT' (3 nucleotides at position 20 to 22 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'TACGATCCCTCC' (12 nucleotides at position 107 to 118 in the user submitted sequence), (do not cause frameshift); ctctggtggctccgtcagaGATttttattactggagttgggtccggcagcccccagggaagggactggagtggcttggatatctctattacagagggagcaccaagTACGATCCCTCCtataatccctccctcgagagtcgagtcaccatttcagttgacccgtccaagaaccagttctccctgaagctaaactctgtgaccgctgcggacacggccgtgtattactgcgcgagaggtgggtccggtggggccctactggaatctgatccggggactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +3325 JY8QFUQ01BVFXH No results +3326 JY8QFUQ01CRKC4 No results +3327 JY8QFUQ01CA3C0 productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3328 JY8QFUQ01BVMA3 No results +3329 JY8QFUQ01CH3TH productive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3330 JY8QFUQ01BXY7M productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 7 8 13 7.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 23 in the user submitted sequence), (cause frameshift) cctctggattcacctttagtagtttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +3331 JY8QFUQ01DE0O0 productive Homsap IGHV4-61*03 F, or Homsap IGHV4-61*08 F 861 88.18 194/220 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD5-24*01 ORF 1 10 7 19 10.7.19 [1.17.38.11] CARLRRMVPVSTYYYHSLDVW in-frame + ctccggtgcctccgtcaactatgatgcttactactggagttggatccggcagcccccagggagtccactggagtggattgggtatgcccatcacagtgggagcaccaactacaacccctccctcaggagtcgagtcaccatttcagttgacccgtcgaagaataacttctccctgaggctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacttcgaaggatggttccagtttcgacctactactaccacagtttggacgtctggggccaagggaccacggtcaccgtcttctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcacgcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +3332 JY8QFUQ01AJX06 No results +3333 JY8QFUQ01BBTR2 unknown (see comment) Homsap IGHV3-13*01 F (see comment) 356 67.44 116/172 nt 8 7 X 8.7.X [1.17.24.X] null + No rearrangement found stop codons Low V-REGION identity (67,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgctggattcaccctcagttcctacgacatgcactgggtccgccagactacaggaaaaggtctggagtgggtctcaggtataagcactgacggtgacacatactattcaggctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3334 JY8QFUQ01CH6O1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 1 8 8 X 8.8.X [1.17.37.11] CAREGGGAVRRK#YFDYW out-of-frame - in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccaggggactctgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgcgagaggggggcggggcagttcgtcggaagactactttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3335 JY8QFUQ01DEWRA productive (see comment) Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 99.07 214/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctcctccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3336 JY8QFUQ01BIQ9H unknown (see comment) Homsap IGHV3-11*01 F (see comment) 707 80.28 175/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcaccttcagcgacaactacatgagctggatccgccaggctccagggaaggggctggattgggtttcatacattagtagtagtggtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcacttttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3337 JY8QFUQ01DK7UI No results +3338 JY8QFUQ01DA2I2 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 840 88.32 189/214 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 12 8.8.12 [0.17.38.11] CAKQTVASSSFDFW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) tggatacacttttgccttctactggatcgcctgggtgcgccaggagcccgggaaaggcctggagtggatgggaatgatctatcctgatgactctagaagcagatatagtccgtccttccaaggccaggtcaccatgtcagtcgacaagtccatcgacaccgcctacctgcaatggagtagcctgaaggcctcggacaccgccacttattactgtgcgaaacaaacggttgcttcatcttcctttgacttttggggccaggggaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3339 JY8QFUQ01C18QQ No results +3340 JY8QFUQ01CGLB0 No results +3341 JY8QFUQ01CZNP8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 922 92.13 199/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagcctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3342 JY8QFUQ01CIF07 No results +3343 JY8QFUQ01C09L3 No results +3344 JY8QFUQ01ALPU7 No results +3345 JY8QFUQ01CCDML productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 823 87.04 188/216 nt 85.65 185/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); gtctctggggactccattagtggttactattggacgtggatccggcagAgccccagggaagggactggagtggattggaaatgtccattacacCtgggagtaCccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +3346 JY8QFUQ01DRFQG productive (see comment) Homsap IGHV4-39*02 F 839 86.88 192/221 nt 86.43 191/221 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtgaccccatcggcaacactgcttactcctGggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +3347 JY8QFUQ01BSHAA No results +3348 JY8QFUQ01AP9X6 No results +3349 JY8QFUQ01BQ4Y6 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 119 54.62 71/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +3350 JY8QFUQ01CLJK6 productive Homsap IGHV3-72*01 F 975 93.27 208/223 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD4-11*01 ORF 1 8 10 13 8.10.13 [1.17.38.11] CVRGLQSNYYGMDVR in-frame + ctctggattcaccttcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtagtagagacaaaattaacagttacagtacagaatatgccgcgtctgcgaagggcagattcaccatctcaagagatgaatcaaagaatttactgtatctgcaaatgaacagcctgagaagcgaggacacggccgtatattactgtgttagaggcctacagagtaattactacggtatggacgtcaggggccaggggaccacggtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +3351 JY8QFUQ01C186Z productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD4-23*01 ORF 3 8 8 13 8.8.13 [1.17.38.11] CAKVGSTVVGDFDYW in-frame + ctctggattcaccttcagtagctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgaaagtagggtcgacggtggtaggggactttgactactggggccagggaacccgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +3352 JY8QFUQ01AYOID productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggaacacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +3353 JY8QFUQ01CKTZ9 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 320 72.44 92/127 nt 8 8 X 8.8.X [1.17.8.X] null - No rearrangement found Low V-REGION identity (72,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttaacaactatgccatgggctgggtccgccaggctccagggaaggggttggagtgggtctcatctattagtactagtggtcatcgcctgcctggtccagggcttcttccccca +3354 JY8QFUQ01BNVVK unproductive Homsap IGHV3-30*01 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD3-3*01 F 1 8 7 X 8.7.X [1.17.38.11] CACGHMRDGYDVW# out-of-frame + in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctgggggcccaagggacaaaggtcaccgtctcttcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +3355 JY8QFUQ01B09D0 productive Homsap IGHV3-11*01 F 833 87.16 190/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CVREVTGVWDWFDPW in-frame - cctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3356 JY8QFUQ01C7O3Y No results +3357 JY8QFUQ01A6T30 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 696 80.84 173/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +3358 JY8QFUQ01DG9SE productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); cctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtCaaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3359 JY8QFUQ01DTUR2 productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctccgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3360 JY8QFUQ01A3HCE productive Homsap IGHV3-11*01 F 823 87.04 188/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CVREVTGVWDWFDPW in-frame + tctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3361 JY8QFUQ01COCTJ productive Homsap IGHV1-18*01 F 1002 96.73 207/214 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [0.17.38.11] CARGALGGYSYGMDVW in-frame - aggttacacctttaccagctatggtattagctgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcagcgtttacaatggtaacacaaactatgcagagaagctccagggcagagtcaccatgaccacagacagatccacgagaacagcctacatggagttgaggagcctgagatctgacgacacggccgtgtattactgtgcgagaggggctctagggggctactcctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +3362 JY8QFUQ01DV1Y1 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 336 72.73 96/132 nt 8 7 X 8.7.X [1.17.10.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DV1Y1 ; 8 AA in Homsap_IGHV3-74*01), and low V-REGION identity (72,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcccctttagtatgtattggatgtattgggtccgccaagctcccgggaaggggccggtatgggtcgcacgtatcagtaatgatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +3363 JY8QFUQ01CLZRS productive Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +3364 JY8QFUQ01CZ0HC No results +3365 JY8QFUQ01ANAO8 No results +3366 JY8QFUQ01DKIYF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +3367 JY8QFUQ01AVEXE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 585 92.65 126/136 nt 91.91 125/136 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 X 16 8.X.16 [1.1.35.11] CVRYDYSRLHRSNYFGPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 81 nucleotides (from position 32 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcatcagttatggcatgaactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatctccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +3368 JY8QFUQ01AT5GR No results +3369 JY8QFUQ01AER6E unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 492 84.06 116/138 nt 83.33 115/138 nt 8 8 X 8.8.X [1.16.12.X] null + No rearrangement found Low V-REGION identity (84,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactca +3370 JY8QFUQ01BEQ83 productive Homsap IGHV3-7*01 F 882 89.4 194/217 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactcag +3371 JY8QFUQ01CAR29 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 993 96.26 206/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.16.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaagggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccag +3372 JY8QFUQ01AV54J No results +3373 JY8QFUQ01CGQFF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame + ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagcatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3374 JY8QFUQ01CWZUH No results +3375 JY8QFUQ01A62R0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVKGWNYHSATFGFDYW in-frame + ctctggattcacctttagtgactatgccataagctgggtccgccaggctccaggaaaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccattttcagagacaactccaaagacacgctgtatctgcaaatgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaacctttgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3376 JY8QFUQ01AQVZH No results +3377 JY8QFUQ01CNXIB No results +3378 JY8QFUQ01BJWBZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 922 92.13 199/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CARAYSGPGPYYFDYW in-frame + tccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca +3379 JY8QFUQ01DK8UH productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATDDSNGWDEVADYW in-frame + ctctggattcaccttcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtcagggcttcttccc +3380 JY8QFUQ01AOGMF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +3381 JY8QFUQ01A1LNA productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtctagggcttcttccccca +3382 JY8QFUQ01BX9J5 No results +3383 JY8QFUQ01CRWBY No results +3384 JY8QFUQ01BLPQB unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 471 94.29 99/105 nt 93.33 98/105 nt 8 8 X 8.8.X [1.16.1.X] null + No rearrangement found in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatacattagtaggagtagtactgacatatact +3385 JY8QFUQ01DGLN7 No results +3386 JY8QFUQ01DT1VZ No results +3387 JY8QFUQ01BI9ZZ No results +3388 JY8QFUQ01DT88Q unproductive (see comment) Homsap IGHV4-61*01 F 830 86.43 191/221 nt 85.52 189/221 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 10 7 12 10.7.12 [1.17.38.11] CARAGGWTPYFDSW in-frame - stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 58 of V-REGION: 'T' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 86 of V-REGION: 'A' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcaacagtggtaattactactggaactggatccgccaatccccagggaagggactggagtggattggatatatctactaTgcttggggccaccaacctgcccccctccctcaagaaccgagtcaccatatcgagagacacgtccaagaaccaAgttttccctgaggttgacttctgtgaccgctgcggacacggccatatattactgtgcgagggccggtggctggaccccctactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3389 JY8QFUQ01AXAUU No results +3390 JY8QFUQ01C6VR6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3391 JY8QFUQ01CH3X2 productive Homsap IGHV3-48*03 F 825 88.15 186/211 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 7 8 13 7.8.13 [X.17.38.11] CARDKGWSGYGMDVW in-frame + attcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +3392 JY8QFUQ01DD3NU unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +3393 JY8QFUQ01DSA0R unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 117 54.76 69/126 nt 8 8 X 8.8.X [1.17.8.X] null + No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttctt +3394 JY8QFUQ01DDMLQ No results +3395 JY8QFUQ01BLBRH unproductive Homsap IGHV3-49*01 F, or Homsap IGHV3-49*03 F or Homsap IGHV3-49*05 F (see comment) 660 77.13 172/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 10 X 8.10.X [1.17.38.11] CAGLLSHLT#W out-of-frame + Low V-REGION identity (77,13% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgatgtggtcggcttcggggcttacacaatgacttggttccgcttgcctccagggaggggcctggaattggtaggtttcatcaggagcacgggaaacggtgggacaacagagtacgccgcgtctgtgagaggcagagtcttcatctcaagagatagatccaacaatgtcgcctatctacaaatgaacaatctgaagaccgaggacaccgccatatattattgcgctggactcctttcccatttgacatatggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3396 JY8QFUQ01DFF6W unknown (see comment) Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagatttacggattactggggcccagggaaccctggtcaccgtttgcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtccgcatgcctggtccagggcttcttccccca +3397 JY8QFUQ01DPAO2 productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +3398 JY8QFUQ01DQRIP No results +3399 JY8QFUQ01CW5LL productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-11*01 ORF 2 8 7 17 8.7.17 [1.17.38.11] CARVGRSVGYSDSGWFDPW in-frame + tctctggtggctccatgagtagttactactggaactggattcggcagcccccagggaagggactggagtggattgggtatatctattacactgggatcaccaactacaatccctccctcaagagtcgagtcaccatgtcaatagacacgtccaggaagcagttctccctgaccctgacctctgtgaccgctgcggacacggccgtctatttctgtgcgagagtcggccggagtgtgggctacagtgactctgggtggttcgacccctggggccagggaaccctggtcaccgtctcctcaccatccccgaccagcccaaggtcttccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggggcttcttcccc +3400 JY8QFUQ01DMBMA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 949 93.52 202/216 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + tctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3401 JY8QFUQ01DNDYD unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 388 87.13 88/101 nt 8 7 X 8.7.X [1.17.X.X] null - No rearrangement found cctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcagctattagtggtagggtgttgaca +3402 JY8QFUQ01AVUV9 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccagggaaggggctggagtgggtctcaactattcgtgcccgtggtgataggacacactacgcggactccgtgaagggccgcttcaccatctctagagacaattcaaaggacaccctgtatttgcaaatgtacagcctgcgagtcgaggacacggccgtctattactgtgcgaacgaagtcgggtactgtagtagtgggggggaccaggggaccctggtcaccggtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3403 JY8QFUQ01CVSFA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 856 90.0 189/210 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [X.17.38.11] CTRDIGGRYSYW in-frame + ttcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3404 JY8QFUQ01CJJOB productive (see comment) Homsap IGHV3-7*03 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tccggattcacttttagtgactattggatgagttgggtccgccaggctccagGggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3405 JY8QFUQ01AKAN3 productive (see comment) Homsap IGHV3-11*01 F 925 92.96 198/213 nt 92.49 197/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagaaccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3406 JY8QFUQ01CXXIO productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGHSYYVSSGPDYW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01CXXIO ; 7 AA in Homsap_IGHV3-53*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ttcggggttcaccgtcagtagcaagtacatgacctCgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagcagtgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3407 JY8QFUQ01DE4P9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctatatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +3408 JY8QFUQ01AIVPA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 178 to 178 in the user submitted sequence), (cause frameshift); ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatTgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa +3409 JY8QFUQ01CLL6Y productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1013 96.33 210/218 nt 95.87 209/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 3 8 8 20 8.8.20 [1.17.38.11] CARLPYIVVLTNIISPTYFDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); tttctggaGtacagttttaccagttactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctgctgactctgataccagatacagcccgtccttccaaggccaggtcagcatctcagccgacaagtccatcgacaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgcggctgccatatattgtggtgctgactaatataatctccccaacctactttgacttctggggccagggaacccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3410 JY8QFUQ01C2IMN No results +3411 JY8QFUQ01A35DO unproductive (see comment) Homsap IGHV4-61*01 F 947 92.31 204/221 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctctggtggctccatcagcggtagtactaactactggagctggattcggcagcccccagggaagggactggaattcattgggtatatctattccagtgggaggaccaactacaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccagttctccctgaggctggcgtctgtgaccgctgcggacacggccgtgtattactgtacgaggggggcagtacacttatgacagcccgtggggacaggggacccctggtcagccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3412 JY8QFUQ01CY6QY No results +3413 JY8QFUQ01DA7X2 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 856 87.67 192/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found gcctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3414 JY8QFUQ01DO5F5 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1071 99.54 216/217 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARLHGYCGGGYCYDWYFDLW in-frame + ttctggatacagctttaccagctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgattccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgagactccatgggtattgtggtggtggttattgctacgactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3415 JY8QFUQ01CXQMU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 895 90.74 196/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAGDLTGVPYYYDSSGLKYW in-frame + tctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +3416 JY8QFUQ01A9YP9 No results +3417 JY8QFUQ01APABC productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 875 88.24 195/221 nt 87.78 194/221 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARQRYYESDGQTW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaccggaagtagttattattggggctggattcgccagTcccccagggaaggggctggagtggattggaagtatgtattacactgggagcaccgactacaacccgtccctcaagagtcgggtcacgatatccgcagacaagtcgaagagccaggtctacctgaagttggactctgtgaccgccgcagacacaggtgtttattactgcgcgagacaaaggtactatgaaagtgatggccaaacctggggccagggaatcctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttc +3418 JY8QFUQ01B4IUJ No results +3419 JY8QFUQ01ATC1E No results +3420 JY8QFUQ01ABR6O No results +3421 JY8QFUQ01B6YN6 unknown (see comment) Homsap IGHV3-11*01 F (see comment) 756 83.41 181/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccctcagtgactacagtatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatacatcagccgaagtggaagtaatgtggaaactgcggactctgtgaggggccgattcaccgcctccagggacaccgccaataattcactgtttctgcggatgaatagcctgacagtcgaggacacggccctctattactgtgcgagagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccgag +3422 JY8QFUQ01DNCXN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-16*02 F 1 8 8 16 8.8.16 [1.16.38.11] CAKDPQQLLEDINWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) ctctggattcacctttcgcagctatgccatgagctgggtccgccaggctcaggaagggggctagagtgggtctcatctatcagtggtagtggtgataaaacaaagtacgcagactccgtgaagggccggttcaccatctccagagacaacgccaggaacacattttatctgcaaatggacagcctcagagccgaggacacggccgtctattactgtgcgaaagatcctcagcagttattggaagacataaactggttcgacccctggggccagggcacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +3423 JY8QFUQ01DVO9C unproductive (see comment) Homsap IGHV3-15*04 F 1011 95.07 212/223 nt 93.72 209/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 X 8.10.X [1.17.38.11] CTTGGWN*L##W out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttGggccgtattgcCaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaaGtatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggttggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccagtcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3424 JY8QFUQ01CIQ3V productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 644 93.84 137/146 nt 93.15 136/146 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 1 8 X 12 8.X.12 [1.8.31.11] CARRDVGLHAFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 72 nucleotides (from position 54 in the user submitted sequence), (do not cause frameshift) gttctggatccaattttaactacgactggatcggctgggtgcgccagatgcccggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgcttttgatctgtggggccaggggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct +3425 JY8QFUQ01DLASW No results +3426 JY8QFUQ01A8HR6 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F (see comment) 728 82.33 177/215 nt Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-3*01 F 2 8 7 10 8.7.10 [1.17.38.11] CARNRWSGFDVW in-frame + Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (highest number of consecutive identical nucleotides) tgtctggtggctccctcacaaattactattacagttggatacggcagaccccagggagaggactggagtggattgcatatatctatgcccgtggcaataccaactacaatccctcctttaggagccgggccaccatatcagtcgacacggctaagaaccagttttccctggagttgaattctgtgaccgcagcggacacggccgtttattactgtgcgagaaaccggtggagcggctttgatgtctggggcccagggacactcatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +3427 JY8QFUQ01CTLVA unproductive Homsap IGHV4-61*02 F 848 86.88 192/221 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CARGMATIKRS#FDPW out-of-frame + tctctggtggctccatgaggagtggaattaattcctggacatggatccggcagcccgccgggaagggactggagtggattgggcgtatctatatcaatggagacaccaactacaatccctccctcaagagtcgggccagcatatcaatggacacgtccaagaaccagttctccctgcacttgacctctgtgaccgccgcagattcggccgtctattattgcgcgagagggatggccacaataaaacggtccgattcgacccctggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3428 JY8QFUQ01BPHVF unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaaggaacctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccctcgcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +3429 JY8QFUQ01AS5EL productive Homsap IGHV4-4*07 F 1061 99.53 214/215 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD4-11*01 ORF 2 8 7 13 8.7.13 [1.17.38.11] CARDFSNRGWYFDLW in-frame + tctctggtggctccatcagtagtttctactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +3430 JY8QFUQ01AHAEV unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 464 91.74 100/109 nt 90.83 99/109 nt 8 8 X 8.8.X [1.16.2.X] null + No rearrangement found in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcacatttagcaactatgccatgagctgggtccgccaggctccagggaagggccggagtgggtctcagctattactggtcttgatggtagaacattctacgc +3431 JY8QFUQ01BMQPR No results +3432 JY8QFUQ01CJAJA No results +3433 JY8QFUQ01DWP1K unproductive Homsap IGHV3-30*10 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CLAEVEAD#FDNW out-of-frame - Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaaggggActagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3434 JY8QFUQ01AOD6D No results +3435 JY8QFUQ01AR4UO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3436 JY8QFUQ01B5293 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKGIVGETFFDHW in-frame + ctctggattcacctttaataactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtactagtggtagtcacactaactacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagggatagtgggagaaactttctttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc +3437 JY8QFUQ01BII7Q No results +3438 JY8QFUQ01AR3J4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3439 JY8QFUQ01DXCD1 No results +3440 JY8QFUQ01DQAM2 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 892 89.95 197/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame - ctctggagttcagccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3441 JY8QFUQ01CDKOP No results +3442 JY8QFUQ01B8A2A productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3443 JY8QFUQ01AMBWC productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3444 JY8QFUQ01ALCRS No results +3445 JY8QFUQ01BMGV5 No results +3446 JY8QFUQ01CCPK9 No results +3447 JY8QFUQ01AV0YA unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggaacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3448 JY8QFUQ01B2MRJ No results +3449 JY8QFUQ01CV95R unproductive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 280 82.14 69/84 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-13*01 F 3 X X X X.X.X [X.X.28.11] CVKIERAAIGTTLRT# out-of-frame + Low V-REGION identity (82,14% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaagatcgaaagggcagcaattggtactactttgagaactgggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3450 JY8QFUQ01BWP0D No results +3451 JY8QFUQ01CMFQ9 No results +3452 JY8QFUQ01BRPAV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3453 JY8QFUQ01BBXWK No results +3454 JY8QFUQ01AYHQQ productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 979 93.69 208/222 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 2 8 10 16 8.10.16 [1.17.38.11] CAADGCPGGTCYHGFDMW in-frame + tctggattcactttcagtaacgtctggatgcactgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgctggtggggcaacagaatacgctgcgcccgtgagaggcatattctccatctcaagagatgattcaaagaacacgttgtatctgcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtgccgcagatggttgtcctggtggtacctgctatcatggttttgatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +3455 JY8QFUQ01CKKEJ No results +3456 JY8QFUQ01DO5OF productive (see comment) Homsap IGHV4-55*03 P (see comment) 734 82.03 178/217 nt 81.57 177/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 9 7 15 9.7.15 [1.17.38.11] CARDQSVYTAGSYFDSW in-frame + Potentially, because of detected insertion/deletion however the closest V is a pseudogene Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); tctctggtgactccatgagtagcgacacgtggtggagctgggtccgccagacgccagagaagggactggaatggattggggagatcaatcaaagagggacgacctcctacaacccgtccctcaggagtcgagtcgtcctgtcagtgggcgagtccaaaaaGtcaattctccctgaggctgacctctgtgaccgccgcggactcggccatctattattgtgcgagagatcagtctgtctatactgcgggaagttactttgactcctggggccagggaacgctggtcaccgtctcttcagcctccacaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3457 JY8QFUQ01BCDBF No results +3458 JY8QFUQ01CIV7S productive (see comment) Homsap IGHV3-7*01 F 880 90.61 193/213 nt 89.2 190/213 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 7 14 7.7.14 [0.17.38.11] CARGSYWHYDTFGDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) ctggatttactttaacaactattggatgacctgggttcgccaggctccagggaagggctggcaatgggtggccaacataaacaacatggaggtgaaacgtactatCgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3459 JY8QFUQ01CRXS1 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 867 89.72 192/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 2 8 7 11 8.7.11 [1.17.38.11] CARDRQSWGIDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccgtcagtaacaactacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggtgacacatactacgcagactccgtgaagggccgattcaccatctccagagacaacgccaagaatacactttttcttcaaatgacttccctgagagtcgaagatacggccatttattactgtgcgagagatcgtcagagctgggggattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3460 JY8QFUQ01AE5BH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactca +3461 JY8QFUQ01CMJK0 No results +3462 JY8QFUQ01B3P8Z productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3463 JY8QFUQ01BUVIO No results +3464 JY8QFUQ01AVY3P No results +3465 JY8QFUQ01CD0J1 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 78 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggcgtggagtgggtctctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3466 JY8QFUQ01AVQLE productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3467 JY8QFUQ01DCZ30 No results +3468 JY8QFUQ01A77JN No results +3469 JY8QFUQ01DDF5Y productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3470 JY8QFUQ01B9X9X productive (see comment) Homsap IGHV3-72*01 F 956 92.76 205/221 nt 92.31 204/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.16.38.11] CITSFGGRSLAYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) tctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +3471 JY8QFUQ01C82CC productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.16.38.11] CARGRIVSVGMSGWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaagggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3472 JY8QFUQ01AJCZV unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 998 96.28 207/215 nt 95.81 206/215 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDNYGDYW# out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3473 JY8QFUQ01A0GMU No results +3474 JY8QFUQ01B5U1N productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARMGYGYRGIYFFDYW in-frame - cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagaatgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +3475 JY8QFUQ01AFC6N unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDLYGADDL## out-of-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccggctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccc +3476 JY8QFUQ01C8SMK No results +3477 JY8QFUQ01CSNZ8 No results +3478 JY8QFUQ01DUM9Y productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +3479 JY8QFUQ01CRXX8 No results +3480 JY8QFUQ01DEFOC productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + ctctggattccccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaggggccgattcaccatctccagagacaacgccaggaactcattgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3481 JY8QFUQ01C5EQN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 558 72.81 158/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (72,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctagattcatctttagtagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactatcagtggtagtggtgataacacatactacgcagactccgtgaagggccggttcaccatctccagagacaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3482 JY8QFUQ01BUTXF No results +3483 JY8QFUQ01AOO53 No results +3484 JY8QFUQ01AF8ND productive Homsap IGHV4-61*02 F 974 93.67 207/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSAPWNDHW in-frame + tctctggtggctccatcagcagcggttattactactggagctggatccggcagcccgccggggagggactggagtgggttgggcgtatctctgccagtggggacaccaactacaacccctccctcaagagtcgagtcaccatatcagtgaacacgtccaagaaccagttctccttgaggctgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagacaaggggacagtagtgctccctggaatgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +3485 JY8QFUQ01BIHMA No results +3486 JY8QFUQ01CGWZP productive (see comment) Homsap IGHV3-7*02 F 899 91.16 196/215 nt 90.23 194/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.38.11] CTRSSNSAYDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 32 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) ctctggattcacgtttagtaacagttggatggctgggcccgccaggctccagggaagggctggagtgggtggccagcacaaaccaagatgcaagtgagaaaaagtatgtggactctgtgaggggccgattcaccatctcaagagacaacgccaagaactcactgtatttacaaatgaacagcctaagagccgaggacacggctttatatttctgtacgaggtccagtaacagcgcttatgactattggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3487 JY8QFUQ01AAQKM No results +3488 JY8QFUQ01AEYEY productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1014 95.91 211/220 nt 95.45 210/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3489 JY8QFUQ01A6RSK unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 302 96.88 62/64 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found ctctggattcaccttcagcagctatagaatgaactgggtccgccaggctccagggaaggggctg +3490 JY8QFUQ01C0RM5 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1010 95.48 211/221 nt 95.02 210/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 2 8 10 10 8.10.10 [0.17.38.11] CTTLPWEPLDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); ctggattcactttcagtaatgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaactagaactgatggtgagacaacagactacgctgcacccgtcaaaggcagattcaccatctcaagagatgattcCaaaaaacacgttgtttcttcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtaccactcttccttgggagcctctcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3491 JY8QFUQ01BY1TX No results +3492 JY8QFUQ01C88VO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3493 JY8QFUQ01DVH7K unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*R##LDYW out-of-frame + stop codons ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggctggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccgag +3494 JY8QFUQ01DJBZ7 No results +3495 JY8QFUQ01B5YDP unproductive (see comment) Homsap IGHV3-66*02 F 854 88.84 191/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD3-3*01 F 1 8 7 19 8.7.19 [1.17.38.11] CATTPAGEPIGSRQ*WF*YLG in-frame + stop codons cctctggactcatcgtcagtggcagctacatgagttgggtccgccaggctcctgggaaggggctagaatggatctcagttatttatagcgatggtagcgcatactacgcagagtccgtgaagggccggttcaccatctccagagacgcttctaagaacacagtttatcttctgatgaacaacctgagaactgaggacacggctgtatattactgtgcgactacccccgcgggggagcccatcggatcccgacaatgatggttttaatatttgggggcccaagggacaatggtcaccgtctcttcagcatcccctgaccagccccaaggtcttcccgctgngcctcctgagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttcccccaa +3496 JY8QFUQ01BGJ03 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-21*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtttattactgtgcgagaggccgaatagtgtcggttggtatgtcaggctggttcgacccctggggccagggaaccctggtctccgtctcctcagcatccccgaccagctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaagggcttcttcccccag +3497 JY8QFUQ01BIMRE No results +3498 JY8QFUQ01A3ZWX productive Homsap IGHV3-23*05 F (see comment) 447 83.08 108/130 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 X 5 16 X.5.16 [X.X.38.11] CVRYDYSRLHRSNYFGPW in-frame + Low V-REGION identity (83,08% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcatcagttatgactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3499 JY8QFUQ01CGAYM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKQKHSYGYYFDQW in-frame - ctctggattcacgtttaaaacacatgccatgagctgggtccgccaggctccaggaaaggggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaaacatagttatggatactactttgaccagtggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3500 JY8QFUQ01B4H2V productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame + tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3501 JY8QFUQ01BOBM8 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcgtctttggcgactatgcgatgagctgggtccggcaggctccagggaggggcgtggagtgggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +3502 JY8QFUQ01C51YK No results +3503 JY8QFUQ01CXKTJ No results +3504 JY8QFUQ01DMIAX No results +3505 JY8QFUQ01AB42J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3506 JY8QFUQ01AQQHX No results +3507 JY8QFUQ01AVFZY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3508 JY8QFUQ01BGC21 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ5*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.16.38.10] CAKSPLSVAGTRQNWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaagggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcct +3509 JY8QFUQ01DE44E productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 89.77 193/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [2.17.37.11] CAKNNNDFGDYDWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 111 in the user submitted sequence), (cause frameshift) gtctctggtgtctccatcagtagttcctactggagttggatccggcagGcccccagggaagggcctggagtggattggttatgtctattatactgggggcaccgactccaaccctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3510 JY8QFUQ01AEQ4Q productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.14 211/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctaCctggagctGggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3511 JY8QFUQ01DW8OU No results +3512 JY8QFUQ01CR4UL No results +3513 JY8QFUQ01BK72L No results +3514 JY8QFUQ01B6617 No results +3515 JY8QFUQ01DLOAA productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaaggGgccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3516 JY8QFUQ01DCFM0 No results +3517 JY8QFUQ01A4L2D No results +3518 JY8QFUQ01APPM5 No results +3519 JY8QFUQ01BMMXG No results +3520 JY8QFUQ01DEN0P No results +3521 JY8QFUQ01B4P0Q No results +3522 JY8QFUQ01AV67L No results +3523 JY8QFUQ01C7T8Q No results +3524 JY8QFUQ01COB96 No results +3525 JY8QFUQ01CCIZW unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 842 87.61 191/218 nt 86.7 189/218 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDQSCIVGPCGFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 91 of V-REGION: 'C' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 98 of V-REGION: 'AGGA' (4 nucleotides at position 199 to 202 in the user submitted sequence), (cause frameshift); cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatCgaacaagcctaggggccagAGGAgcgacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3526 JY8QFUQ01A2P8W unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [1.16.38.11] CVRDRDFLWGSYRLQLEY## out-of-frame + in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) ctctggattcagatttagcagctatggcatgagctgggtccgccaggctccaaaaaggggctggagtgggtctcaggaattagtgcgaatggtggtagtataaattatgcagactccgtgaagggccgattcatcatctccagagacaattccaagaacacattgtttctgcaaatgaatagcctgagagccgaagacacggccgtatattactgtgtgagagatcgcgatttcctgtgggggagttatcgtcttcaacttgaatattggggccaaggaaccctgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3527 JY8QFUQ01A1485 No results +3528 JY8QFUQ01CXERX unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +3529 JY8QFUQ01A7A3Y No results +3530 JY8QFUQ01AGGIL productive Homsap IGHV3-7*01 F 933 91.82 202/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 2 8 8 18 8.8.18 [2.17.38.11] CSRHGGYTRLYNQNVYLDYW in-frame - ggcctctggattcacatttagcaacttttggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaaaataaacccagacggaagtgagaaatactatgtggactctgtgaagggccgattcaccacctccagagacaactctagaaactcgctgtgtctgcaaatggacagcctgagagccgaggacacggctgtgtattactgttcgagacatggaggttacacgagactctacaatcaaaatgtctaccttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3531 JY8QFUQ01CYTT3 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 895 90.74 196/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 7 8 13 7.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) cctctggatcaccttggttattgatggcatgagctggtccgccaagctccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3532 JY8QFUQ01B4JGT No results +3533 JY8QFUQ01CPSCG unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 491 84.56 115/136 nt 83.82 114/136 nt 8 8 X 8.8.X [1.16.11.X] null + No rearrangement found Low V-REGION identity (84,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc +3534 JY8QFUQ01CWIF1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame - cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcatgcctggtccagggcttcttccccc +3535 JY8QFUQ01ANZNP productive Homsap IGHV3-9*02 F 882 89.86 195/217 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD3-9*01 F 3 8 8 11 8.8.11 [1.17.38.11] CGKDMRLGGMDVW in-frame + ctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgaaagttgaggacacggccatgtattactgtggaaaagatatgcgactgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3536 JY8QFUQ01A8U8B No results +3537 JY8QFUQ01CCQKT No results +3538 JY8QFUQ01AURV3 No results +3539 JY8QFUQ01BDTBC unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 1 8 8 X 8.8.X [1.17.37.11] CAREGGGQFVG##YFDYW out-of-frame - stop codons in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 156 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccaggggactctgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgcgagaggggggcgggcagttcgtcggaagactactttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3540 JY8QFUQ01CNTXZ No results +3541 JY8QFUQ01C9T65 productive Homsap IGHV3-30*01 F 878 89.45 195/218 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [1.17.38.11] CACGHMRDGYDVW in-frame - cctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3542 JY8QFUQ01B9OYU productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.16.38.11] CARDPVGISGSVNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaagggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3543 JY8QFUQ01A88IP productive Homsap IGHV3-9*01 F 968 94.04 205/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*03 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - cctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3544 JY8QFUQ01CCSP4 No results +3545 JY8QFUQ01APOI8 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 85 51.49 69/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcacctttaacctctatgtcatgcactggttccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3546 JY8QFUQ01ARWSX No results +3547 JY8QFUQ01BBZ9B No results +3548 JY8QFUQ01CBJ3B No results +3549 JY8QFUQ01BA6WI productive Homsap IGHV4-39*03 F 920 90.91 200/220 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-14*01 ORF 2 10 7 12 10.7.12 [1.17.38.11] CTREGPYYYGMDVW in-frame + tctctggtgactccatcagtaatactgattactactgggtctggatccgccagaccccagggaagggactggagtggattgggagtatcgatttcagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccatagacacgtccgagaaccggttctccctgaggttgacctctatgaccgccgcagacacggccgtctattactgtacgagagagggaccctactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3550 JY8QFUQ01DRIVX productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +3551 JY8QFUQ01CR8FZ No results +3552 JY8QFUQ01B9CQM No results +3553 JY8QFUQ01B2Q8V No results +3554 JY8QFUQ01B9ZY4 No results +3555 JY8QFUQ01DH2JR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 917 92.09 198/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDQSLGMPEAFDIW in-frame + ctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +3556 JY8QFUQ01DQXN3 productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDGYYYYHSGMDVW in-frame + ctctggattcacttttagcagtttttggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagtgggatggaagtgataaaaagtatatggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactatatctgcaaatgaacagcctgagagccgaggacacggctgtatattattgtgcgaaagacggctattattattatcacagcggtatggacgtctggggccaagggaccacggtcatcgtctccccaagcatccccgaccagccccgaaggtcttcccagctgacgctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +3557 JY8QFUQ01AU1X2 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 2 9 7 11 9.7.11 [2.17.38.11] CARASTLRYLDRW in-frame - gtctctggtggctccatcagcagtgataattggtggagttgggtccgccagcccccagggaagggactggaatggattggggaaatatatcatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacaagtccaagagtcaattcttcctggagctgaggtctgtgaccgccgcggacacggccgtatattattgtgcgagagcctccacactacgatatcttgaccgctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +3558 JY8QFUQ01DG3GX productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 982 94.52 207/219 nt 94.06 206/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaAGggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3559 JY8QFUQ01BN2A0 No results +3560 JY8QFUQ01ALROO unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaact +3561 JY8QFUQ01DCAFK productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggcGtggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccCctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3562 JY8QFUQ01BE1SO unknown (see comment) Homsap IGHV4-30-2*04 F, or Homsap IGHV4-34*01 F or Homsap IGHV4-34*02 F or Homsap IGHV4-34*08 F or Homsap IGHV4-34*12 F or Homsap IGHV4-34*13 F or Homsap IGHV4-38-2*01 F or Homsap IGHV4-38-2*02 F or Homsap IGHV4-39*01 F or Homsap IGHV4-39*05 F or Homsap IGHV4-59*04 F or Homsap IGHV4-59*05 F or Homsap IGHV4-59*08 F 418 91.92 91/99 nt X X X X.X.X [X.X.33.X] null - No rearrangement found stop codons ctatggagtcgagtcaccatatgagtagacacctccaagaaccagttctccctgaaggtgagctctgtgatcgccgcagacacggctgtgtattactgtgcgagacgtaagggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3563 JY8QFUQ01DW4KO unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 89 58.57 41/70 nt 8 X X 8.X.X [1.14.X.X] null + No rearrangement found ctctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttcccc +3564 JY8QFUQ01AYH21 No results +3565 JY8QFUQ01DPK2Q productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCGNGACHVADYW in-frame + ctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3566 JY8QFUQ01C608B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3567 JY8QFUQ01BHUTE No results +3568 JY8QFUQ01AYYZI No results +3569 JY8QFUQ01B393V No results +3570 JY8QFUQ01AXYLH No results +3571 JY8QFUQ01AQUPN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1006 97.18 207/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 11 8.8.11 [X.17.38.11] CVVQILGATIDYW in-frame + ggattcaccttcaatacctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtggtagtacttacataaagtacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtggtccagatcctaggggctacgattgactactggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +3572 JY8QFUQ01BB2PN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccagtgacggtgtcgtggaactca +3573 JY8QFUQ01CWLL0 productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaactcag +3574 JY8QFUQ01BGMHI No results +3575 JY8QFUQ01CG65B No results +3576 JY8QFUQ01CWI6C productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 768 82.96 185/223 nt 82.51 184/223 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [2.17.38.11] CARHRSFGVIIVNYFESW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); atttcccggtgactccatcaccagtactaattattactggggctgggtccgccagtccccagggaagggtctggagtggattggaagtgtctattatCggggggacccagtacctcaacccgtctctccacaatcgagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtcttttggagtgataattgttaactactttgagtcctggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3577 JY8QFUQ01BAR2U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGRATGLVDWFDPW in-frame + ctctggattcaccttcaccaactacgccatgacctgggtccgccaggctccagggaaggggctggagtggatctcgactgttgtgggtggcggtggtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattcccagaacacgctgtatttgcaaatgtacaatttgggagccgaggacacggccctatattactgtgcgagaggtagagcgactggtctggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagcagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3578 JY8QFUQ01C9E4I unproductive Homsap IGHV3-48*01 F 859 88.89 192/216 nt 87.5 189/216 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.16.38.11] CARASTFYYDGSGYRD#FDIW out-of-frame - in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggcttcagtttgagtacttataccatgGaactgggtccgccaggctccaggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggGactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3579 JY8QFUQ01BKVA2 productive Homsap IGHV3-7*01 F 928 91.78 201/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [2.17.38.11] CARGSYWHYDTFGDYW in-frame - gcctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +3580 JY8QFUQ01C2JLD productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +3581 JY8QFUQ01BNZDJ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 377 75.94 101/133 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (75,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +3582 JY8QFUQ01A3HY6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 825 86.36 190/220 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found agcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccaggggaaggggctgagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3583 JY8QFUQ01CMS5Z No results +3584 JY8QFUQ01ANNT6 productive (see comment) Homsap IGHV3-30*07 F, or Homsap IGHV3-30*16 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.16.38.11] CARDSVPRASEAAYYFDSW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtatttattctatgcattgggtccgccaggccccaggcaagggctagagtgggtggcagttatatcacatgatggaactaataaatattactcagactccgtgaagggccgattcaccatctccagagacaattccaagagcgcgctgtatctgcagctgaacgtcctgagcgccgaggacacggctgtctatttctgtgcgagagattccgtacctcgggcgtcagaggctgcctactactttgactcttggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3585 JY8QFUQ01DNX9B unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 849 88.79 190/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-14*01 ORF 1 8 8 X 8.8.X [0.17.38.11] CARGIVVYSESESPTTPK#DYW out-of-frame + tggatacaccttcagcaacttctatatatattgggttcgacaggcccctggacaagggcttgattacataggagtattcaaccctagtggtggtaacaccaggtacgcacagaagttccaggacagagtcaccgtgaccagtgacacgtccacgaacacagtgtacatggagctgagtaggctgagatctgaagacacggccgtgtattactgtgcgagagggatagtggtttactctgaatcggaaagtccgacaaccccgaaaatgactactggggccagggaacccgggtcatcgtctcctcagcttccaccaagggcccatccgtcttccccgtggcgccctgctccaggagcacctccgagagcacagccgcccatgggctgcctggtcaaggactacttccccagaaccggtgacggtgtcgtggaactcag +3586 JY8QFUQ01C7CBC productive Homsap IGHV1-2*02 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame + tggatatactttcaccgaccattatgtttactggatgcgacaggcccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3587 JY8QFUQ01BX1RT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +3588 JY8QFUQ01AJX0L No results +3589 JY8QFUQ01AVVL2 No results +3590 JY8QFUQ01C8N0Q No results +3591 JY8QFUQ01C84TZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 883 89.5 196/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [2.17.38.11] CSKDTFGREDYW in-frame - gcctctggattctccgtcagtaattactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3592 JY8QFUQ01DD1D4 unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 777 83.41 186/223 nt 82.51 184/223 nt Homsap IGHJ3*01 F (see comment) 151 78.0 39/50 nt Homsap IGHD3-9*01 F 3 7 9 X 7.9.X [2.17.38.11] CATDSPTGYYA#FDVW out-of-frame - stop codons Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 27 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 88 in the user submitted sequence), (cause frameshift) gcctctgggtcgatttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcattttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3593 JY8QFUQ01DBXJG No results +3594 JY8QFUQ01DW47I No results +3595 JY8QFUQ01CCVPU productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 903 91.59 196/214 nt Homsap IGHJ3*02 F (see comment) 133 74.0 37/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaacggtcaccggtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +3596 JY8QFUQ01CS83G unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagg +3597 JY8QFUQ01DSAWM productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcacctttgatgattttggcatgagatgggtccgccaagtcccagggaaggggctacagtgggtctctgggattaattggaatggtgctaaaacaggttatgcagcctctgtgcagggccgattcaccatctccagagacaacgacaacaacgtcctgtatctgcaaatgaacagtttgagacccgaggacacggccttgtatcgctgtgcgagagaggtttcggacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +3598 JY8QFUQ01CJV25 No results +3599 JY8QFUQ01AJSSD productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD3-10*01 F 1 8 8 19 8.8.19 [1.17.38.11] CARPAFLWFGDLPAEDGFDVW in-frame + tctggatacagctttaccaattactggatcggctgggtgcgccaggtgcccggaaaaggcctggagtggatggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcagtaccgcctaccttcagtggagcagtctagcgacctcggacaccgccatgtattactgtgcgagaccagcttttctctggttcggggacttaccggccgaggatggttttgatgtctggggccaaggaacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +3600 JY8QFUQ01CJ8QL No results +3601 JY8QFUQ01AYBE9 productive (see comment) Homsap IGHV3-33*03 F 926 92.56 199/215 nt 92.09 198/215 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 99 in the user submitted sequence), (cause frameshift) tctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3602 JY8QFUQ01CCYFS No results +3603 JY8QFUQ01BGN8C unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 199 78.46 51/65 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found tctggattcagtttcagtacctatgcaatgcactgggtccgccaggctccagggcttcttccccc +3604 JY8QFUQ01C03FW No results +3605 JY8QFUQ01BPADK No results +3606 JY8QFUQ01AN937 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 776 83.71 185/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARQSEPANNFNDPSRYFFDTW in-frame + Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcccgtgtctccatttccattaatgattactactggggctggatccgccagcccccaggaaagccgctggagtggattgggactgtccattcccttgggtacaattacaacaacccgtccctcaagagtcgactcaccatttccgcagacacgtccaggaatcagatctccctgaaactgacgtctgtgaccgccgcagacacggctgtctatttctgtgcgagacagagcgagcccgccaataacttcaatgacccaagtcgttatttctttgacacttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3607 JY8QFUQ01A2748 No results +3608 JY8QFUQ01A0EII No results +3609 JY8QFUQ01AA9N3 unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F (see comment) 363 64.22 131/204 nt 63.73 130/204 nt 8 7 X 8.7.X [1.17.34.X] null + No rearrangement found Low V-REGION identity (64,22% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +3610 JY8QFUQ01DCC4H unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt 84.79 184/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CARRSGRDGG#WFDSW out-of-frame + in FR3-IMGT at codon 84 of V-REGION: 'C' (1 nucleotides at position 155 to 155 in the user submitted sequence), (cause frameshift); ctctggattcatctttgccgactatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtcgcagatattaatggaagaggtgctgccgcacactacgcagactccgtgacgggccgcttcaccctctacaaagacggttccCaagaatacgatgtatctgcaaatgaggaccctgagagacgacgacacggccaaatattactgtgcgagacgaagtgggcgtgatgggggcctggttcgactcctggggccagggaacccgtggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +3611 JY8QFUQ01C0QV3 No results +3612 JY8QFUQ01DNCPQ productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 709 81.69 174/213 nt 81.22 173/213 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.37.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 130 in the user submitted sequence), (cause frameshift) ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +3613 JY8QFUQ01CILSN No results +3614 JY8QFUQ01DNNQS No results +3615 JY8QFUQ01AZWL7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATSRGSANWYPFDHW in-frame - cctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3616 JY8QFUQ01C9XRD productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaacctcag +3617 JY8QFUQ01BLQLI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [1.17.38.11] CAKEGNLGYFDDW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3618 JY8QFUQ01B2DEP unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 97 66.0 33/50 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.37.11] CARRDVGLHAFDL## out-of-frame + in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 127 in the user submitted sequence), (cause frameshift) ttctggatccaattttaactacgactggatcggctgggtgcgccagatgcccggtaaaggcctggagtggatgggaatggtctatgttggtgactctgatgctagatacagcccgtcctcccaaggcaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgcttttgatctgtggggcccaggggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3619 JY8QFUQ01DGCW9 No results +3620 JY8QFUQ01AAXZI No results +3621 JY8QFUQ01CVZ9K productive Homsap IGHV3-7*01 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [2.17.38.11] CAGGRGWLIDYW in-frame - gcctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3622 JY8QFUQ01AYFJR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 103 66.04 35/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcacccgtggtcactgtctcctcagcctccaccaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3623 JY8QFUQ01AZRBP No results +3624 JY8QFUQ01BAC4O No results +3625 JY8QFUQ01BCU1Y productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1009 93.86 214/228 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [2.17.38.11] CARGSSRGGRSDVNYYELDFW in-frame + tctccgggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggcctcgagtggctgggaaggacatactacaggtccaagtggtattatgactatgcagtgtctgtccaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagctgaattctgtgactcccgaggacacggctgtgtattactgtgcaagagggtccagccgcggggggagatctgatgtgaactactatgagctggacttctggggccagggaatcctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +3626 JY8QFUQ01C2UF8 No results +3627 JY8QFUQ01DHR7Q unproductive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-8*02 F 3 8 7 X 8.7.X [1.17.38.11] CARGSSK#YNWFDPW out-of-frame - cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3628 JY8QFUQ01B2B42 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 216 97.78 44/45 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found ctctggattcaccttcagtagctactggatgcactgggtccccca +3629 JY8QFUQ01DH7E7 No results +3630 JY8QFUQ01BCLRL productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3631 JY8QFUQ01BDV0U unknown (see comment) Homsap IGHV4-61*07 F 853 88.73 189/213 nt 87.79 187/213 nt 8 7 X 8.7.X [2.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 36 of V-REGION: 'GAT' (3 nucleotides at position 22 to 24 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'TACGATCCCTCC' (12 nucleotides at position 109 to 120 in the user submitted sequence), (do not cause frameshift); tctctgggtggctccgtcagaGATttttattactggagttgggtccggcagcccccagggaagggactggagtggcttggatatctctattacagagggagcaccaagTACGATCCCTCCtataatccctccctcgagagtcgagtcaccatttcagttgacccgtccaagaaccagttctccctgaagctaaactctgtgaccgctgcggacacggccgtgtattactgcgcgagagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3632 JY8QFUQ01CYTFV No results +3633 JY8QFUQ01CCPCW No results +3634 JY8QFUQ01DKHTU productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD3-10*01 F 1 8 8 19 8.8.19 [1.17.38.11] CARPAFLWFGDLPAEDGFDVW in-frame + ttctggatacagctttaccaattactggatcggctgggtgcgccaggtgcccggaaaaggcctggagtggatggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcagtaccgcctaccttcagtggagcagtctagcgacctcggacaccgccatgtattactgtgcgagaccagcttttctctggttcggggacttaccggccgaggatggttttgatgtctggggccaaggaacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3635 JY8QFUQ01AHJC8 No results +3636 JY8QFUQ01AELXN unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 449 72.47 129/178 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (72,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3637 JY8QFUQ01ATTEO productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1057 99.07 214/216 nt 98.61 213/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [2.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3638 JY8QFUQ01BIJ6A productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattccccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaggggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatcccgaccagccccaagggtcttcccgctgagcctcganagcaccccccaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccccca +3639 JY8QFUQ01BIM1I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3640 JY8QFUQ01CQ3VH unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEQGAIL*WW*LP#FDYW out-of-frame + stop codons ctctggattcacctttagcagaaatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtagtggtggtagcacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtttatgcaaatgaacagcctgagagacgaggacacggccgtatattactgtgcgaaagaacaaggggcgatattgtagtggtggtagctgccccatttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3641 JY8QFUQ01BOZDA No results +3642 JY8QFUQ01BGZCE No results +3643 JY8QFUQ01DR19K No results +3644 JY8QFUQ01CWJC9 No results +3645 JY8QFUQ01A2ZZU unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +3646 JY8QFUQ01ATX94 productive (see comment) Homsap IGHV3-72*01 F 961 92.79 206/222 nt 92.34 205/222 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.16.38.11] CITSFGGRSLAYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +3647 JY8QFUQ01CBXG3 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 102 53.03 70/132 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3648 JY8QFUQ01A3DOT No results +3649 JY8QFUQ01BYNF3 productive (see comment) Homsap IGHV3-48*01 F 859 88.89 192/216 nt 87.5 189/216 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.16.38.11] CARASTFYYDGSGYRDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggcttcagtttgagtacttataccatgGaactgggtccgccaggctccaggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggGactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgcttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3650 JY8QFUQ01DC8LT productive (see comment) Homsap IGHV3-7*01 F (see comment) 702 80.65 175/217 nt 79.72 173/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); ctctggattcgtctttactaatcattggatgagAttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaatacgaaatacttttggggactctgtgaaggGgccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3651 JY8QFUQ01ATSDY No results +3652 JY8QFUQ01DFOZG productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaTggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagGaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3653 JY8QFUQ01A9M3F No results +3654 JY8QFUQ01CB1JU productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-7*01 F 3 8 7 10 8.7.10 [1.17.38.11] CARDLGGSLDYW in-frame - tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagagatctcgggggatccttggactattggggccagggaaccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3655 JY8QFUQ01B2NLS No results +3656 JY8QFUQ01COYPY productive Homsap IGHV3-66*02 F 921 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 7 17 8.7.17 [1.17.38.11] CSTPTYCRGGSCSQIFDYW in-frame + ctctggattcaccgtcagtaactaccacatgaggtgggtccgccaggctccagggaaggggctggagtgggtctcagttatttacagcggtggtagtacatattacatagactccgtgaagggccgattcaccatctcgagagacgattccgagaacacagtgtatcttcaaatgaagagcctgagagctgaggacacggctgtatattactgttcgacgcccacatattgtaggggcggtagctgttcccagatttttgactattggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +3657 JY8QFUQ01C09X0 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt 99.55 219/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3658 JY8QFUQ01AQJM4 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F (see comment) 775 84.02 184/219 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-9*01 F 2 10 7 11 10.7.11 [1.17.38.11] CARILDGYFFDPW in-frame + Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggtggctccatcgacactcaaaattactactggggctggattcgccagcccccagggacgggactggagtgggttggcagtgtccgctatggcgagagcacctattacaacccgaccctcaaaagtcgactcaccatatccatagacacgtccaggagccagttatccctgagactgagttctgtcaccgccgccgacacggcagtttactactgtgcgaggatcttggatggttacttcttcgacccctggggccagggaacccacgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3659 JY8QFUQ01AIYRL No results +3660 JY8QFUQ01CUCNH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame + ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +3661 JY8QFUQ01DCRYR No results +3662 JY8QFUQ01CXWCQ No results +3663 JY8QFUQ01CEP21 productive Homsap IGHV1-2*02 F 831 87.85 188/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [0.17.38.11] CARDGISMTLVRGVRPFDYW in-frame + tggatacaccttcatcggccattatatacattgggtgcgacaggcccctggacaagggcttgaatgggtggggtggatcaaccctaacagtggtgttacaaactatgcacagcagtttcaggacagggtcaccatgaccgtcgacacgtccatcagcactgcctacatggacctcaaaagtctaaagtctgacgacacggccatctattactgtgcgagagacggaataagtatgactctggttcggggagttaggcccttcgactactggggccagggaaccctggtcagcgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +3664 JY8QFUQ01DS4NL unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 698 80.28 175/218 nt 79.82 174/218 nt 8 8 X 8.8.X [2.17.37.X] null - No rearrangement found Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 124 in the user submitted sequence), (cause frameshift) gcctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgagggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3665 JY8QFUQ01DF7LK unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F 194 56.98 98/172 nt 8 8 X 8.8.X [1.17.23.X] null - No rearrangement found ctctggattcaccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaatggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3666 JY8QFUQ01DE20Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3667 JY8QFUQ01C6LBX productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 937 92.24 202/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'TCC' (3 nucleotides at position 18 to 20 in the user submitted sequence), (do not cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); cctgctggattcgacttTCCaggtagctactgGgatgcactgggtccgccaagctccagggaaggGggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +3668 JY8QFUQ01DDIPQ unknown (see comment) Homsap IGHV3-74*03 F 116 51.34 96/187 nt 8 8 X 8.8.X [1.17.28.X] null + No rearrangement found stop codons tctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3669 JY8QFUQ01CFRXM unknown (see comment) Homsap IGHV3-74*03 F 846 88.02 191/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggcagccctggtccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttcccccaa +3670 JY8QFUQ01CXKD6 No results +3671 JY8QFUQ01DJE9A productive (see comment) Homsap IGHV3-9*01 F 1040 97.71 213/218 nt 97.25 212/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARMTLAPFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); cctctggattcacctttgatgattatgccatgcactgggtccggcaagcGtccagggaagggcctggagtgggtctcaggtattagttggaatagtggtagtataggctatgcggcctctgtgaagggccgattcaccatctccagagacaacgccaagagctccctgtatctgcaaatgaacagtctaagagctgaggacacggccttatattactgtgcaaggatgacactggctccttttgactattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3672 JY8QFUQ01DNH7I unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 714 85.2 167/196 nt 84.69 166/196 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) ctgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttccccctggcgcccttgctccaggagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag +3673 JY8QFUQ01DU08B No results +3674 JY8QFUQ01DEA85 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 76 of V-REGION: 'C' (1 nucleotides at position 133 to 133 in the user submitted sequence), (cause frameshift); ctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcGagctgtgagtagtaggggtgAgtaccacacactacgcagacttcgtgaagggccggCgtcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +3675 JY8QFUQ01BQEZK No results +3676 JY8QFUQ01DBVT7 No results +3677 JY8QFUQ01CHT9Y unproductive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 849 88.79 190/214 nt 87.85 188/214 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*01 F 1 8 8 X 8.8.X [0.17.38.11] CARAGGFQ*TSGE##YYNGLDVW out-of-frame - stop codons in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 75 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); tggatacaccttcagcagttattatatacactgggtgcgacaggAcccccggacaggggcttgagtggatggcaatgatcaacccaagtggtggtagtaccacgtacgcacagaagttccagggcaGgactcatcgtgaccagggacacgtccacgagtagtgtctacatggacctgagtagcctgagatctgaggacacgggcgtctatttctgtgcgagagcgggggggttccagtaaacgtcaggtgaaggactactacaacggtctggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3678 JY8QFUQ01CW4P0 No results +3679 JY8QFUQ01AVTUT No results +3680 JY8QFUQ01AR9R2 No results +3681 JY8QFUQ01DOFOM unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F (see comment) 648 77.42 168/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (77,42% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3682 JY8QFUQ01AV8OV No results +3683 JY8QFUQ01AYE2N No results +3684 JY8QFUQ01CH6ZO No results +3685 JY8QFUQ01CLL92 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3686 JY8QFUQ01A80P5 No results +3687 JY8QFUQ01CMTWR No results +3688 JY8QFUQ01BBJK4 productive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*03 F 558 93.7 119/127 nt 92.91 118/127 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 X 12 8.X.12 [0.3.31.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 35 in the user submitted sequence), (do not cause frameshift) tggatacaccttcaccgtctactatctattctggggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3689 JY8QFUQ01AQ7RC No results +3690 JY8QFUQ01B4WUM No results +3691 JY8QFUQ01AIURT productive Homsap IGHV3-11*03 F, or Homsap IGHV3-11*05 F or Homsap IGHV3-21*04 F 959 93.58 204/218 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 159 75.44 43/57 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSHQVDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtctcatccattagttttgatagtaattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcgctgtttctgcaaatgaacagcctgagagccgatgacacggccgtgtattactgtgcgagagccgtgtcgcatcaggtggacgtctggggccaaggggccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3692 JY8QFUQ01A24Q4 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 454 72.63 130/179 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (72,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3693 JY8QFUQ01AE8PF No results +3694 JY8QFUQ01A2XPS No results +3695 JY8QFUQ01BWXQJ productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame + tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3696 JY8QFUQ01DHQS7 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 387 76.3 103/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (76,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +3697 JY8QFUQ01AU798 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 872 89.77 193/215 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 X 8.7.X [1.17.38.11] CARDRQSW#IDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccgtcagtaacaactacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggtgacacatactacgcagactccgtgaagggccgattcaccatctccagagacaacgccaagaatacactttttcttcaaatgacttccctgagagtcgaagatacggccatttattactgtgcgagagatcgtcagagctggggattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +3698 JY8QFUQ01DACXR No results +3699 JY8QFUQ01BH8Y1 No results +3700 JY8QFUQ01CBC50 No results +3701 JY8QFUQ01CR5SB No results +3702 JY8QFUQ01DG06B productive Homsap IGHV1-18*01 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt 8 8 8 8.8.8 [0.17.38.11] CARGDYFDHW in-frame + tggttacacctttaccagctatggtctcagctgggtgcgacaggcccctggccaagggcttgagtggatgggatggatcttcgtttttaacggtaacacaaaatatgcacagcacctccagggcagagtcaccatgaccacagacacatccacggacacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagaggtgactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +3703 JY8QFUQ01C5K8B unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 215 62.41 83/133 nt 8 6 X 8.6.X [2.17.11.X] null - No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (6 AA in JY8QFUQ01C5K8B ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (62,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +3704 JY8QFUQ01AQY3A productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-16*02 F 3 8 8 11 8.8.11 [1.16.38.11] CAKGQFGTVMDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggattcacctttaacgactatggcatgacttgggtccgccaggctccagggatgggctgcagtgggtcgcaaccattagtggaagtggcgacagaacattctacgcagactccgtgaagggccgcttcatcgtttccagagacaactccaagaacacgctgtatctgcaaattaccagcccgagagccgaggacacggccgttttttattgtgcgaaaggccagtttggtaccgtcatggactattggggccagggaacccaggtcgtcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +3705 JY8QFUQ01A657R No results +3706 JY8QFUQ01CP60I No results +3707 JY8QFUQ01AHSTY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt 86.11 186/216 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcanttccccgaaccggtgacggtgtgcgtgactca +3708 JY8QFUQ01DUOE0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3709 JY8QFUQ01CAMZ2 No results +3710 JY8QFUQ01CQXUA No results +3711 JY8QFUQ01B11DM productive Homsap IGHV4-61*02 F (see comment) 785 84.16 186/221 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARAKDHDDYLVDPW in-frame + Low V-REGION identity (84,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgcctccatcactagtggtacttactactggagttggttccggcagcccgccgggaagacactggaatgggttgggcgtatctatacaactaggagcacctattacaacccctctctcaaaagccgagtcaccgtttcagtcgacgagtcccagaatcagctcttcctggacctgacttctgtgaccgccgcggacacggccgtctacttctgtgcgcgagctaaggaccacgatgactacctggtcgacccctggggccaggggatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3712 JY8QFUQ01BFEAG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt 90.41 198/219 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [2.17.38.11] CANELGYCSGG# out-of-frame - in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgAaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3713 JY8QFUQ01CCYR6 productive Homsap IGHV1-3*01 F 849 88.79 190/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3714 JY8QFUQ01BO1K0 No results +3715 JY8QFUQ01BCAH5 No results +3716 JY8QFUQ01CT1JU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3717 JY8QFUQ01AMILA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 594 77.78 154/198 nt 8 8 X 8.8.X [1.17.31.X] null - No rearrangement found Low V-REGION identity (77,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3718 JY8QFUQ01CBOUK No results +3719 JY8QFUQ01DDJ56 No results +3720 JY8QFUQ01ARU4C No results +3721 JY8QFUQ01DIK53 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYYYHFDYW in-frame - ctctggattcaccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaatggtgcttacatatactacgcagactcaatggagggccgattcaccatctccagagacaacgccaggaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgaaaaagtatcactatggttcggggacttattattaccacttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +3722 JY8QFUQ01DQSCV productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3723 JY8QFUQ01DKEC5 unknown (see comment) Homsap IGHV3-7*01 F 864 88.48 192/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3724 JY8QFUQ01CUPSC No results +3725 JY8QFUQ01AGL22 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 389 75.54 105/139 nt 8 8 X 8.8.X [1.17.11.X] null - No rearrangement found Low V-REGION identity (75,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3726 JY8QFUQ01AF9Z6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcaaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3727 JY8QFUQ01A4TVI productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 937 92.24 202/219 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD6-6*01 F 2 8 8 17 8.8.17 [2.17.38.11] CVRDLAARPPYYYYGMDVW in-frame - gcctctggatttaccttcagtctctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatctattactagtggtagtcattacatctactacgcagactcagtgaagggccgattcaccatctccagagacgactccaagaactcactgtttctgcagatgaacagcctcagagccgaggacacggctgtttattattgtgtgagggatttggcggctcgtcccccttattattactacggtatggacgtctggggccagggggccacggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3728 JY8QFUQ01A98RV No results +3729 JY8QFUQ01DTUI2 productive Homsap IGHV3-48*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3730 JY8QFUQ01B2WK4 No results +3731 JY8QFUQ01CFEC1 No results +3732 JY8QFUQ01A58YS No results +3733 JY8QFUQ01BNO6U No results +3734 JY8QFUQ01A0B46 unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*04 F (see comment) 606 75.7 162/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,70% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +3735 JY8QFUQ01DTTWE No results +3736 JY8QFUQ01CAN9N productive Homsap IGHV3-11*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKDRGKSGSYGLDHW in-frame + tctgggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccagggtcaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgaaagatcgggggaaaagtgggagctacggacttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3737 JY8QFUQ01BUVJJ No results +3738 JY8QFUQ01C3UP7 No results +3739 JY8QFUQ01ALBVT productive Homsap IGHV4-59*03 F 890 90.7 195/215 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-23*01 ORF 3 8 7 9 8.7.9 [1.17.38.11] CARGVTPEGYW in-frame + tctcgggtgactccatcactcctaactcctggagctggatccggcagcccccagggaagggactggagtggattggttatatctattacagtggaatcaccaagcacaacccctccctcaagagtcgagtcgccatttcagtagacacgtccaggaaccaattttccctgaggctgagttctgtgaccgctgcggacacggccgtttatttctgtgcgaggggggtcactccggagggctactggggccagggaatcttagtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +3740 JY8QFUQ01DGY3A No results +3741 JY8QFUQ01AC7VV No results +3742 JY8QFUQ01DPEQC No results +3743 JY8QFUQ01AY97C productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); agtttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3744 JY8QFUQ01BOQIM productive Homsap IGHV4-61*01 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame + tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgggaactcag +3745 JY8QFUQ01DB155 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 176 97.3 36/37 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found ctctggattcatcttcagtagctactggatgcactgg +3746 JY8QFUQ01BLNZS No results +3747 JY8QFUQ01CUIMO No results +3748 JY8QFUQ01CQC4S No results +3749 JY8QFUQ01AD66K productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*03 F 399 86.79 92/106 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 X X 15 X.X.15 [X.X.35.11] CTRELRLAAARDGVDIW in-frame + ctctgggttcaccggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatttggggccaagggacaatggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3750 JY8QFUQ01DJ2BM No results +3751 JY8QFUQ01CA7EB unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 620 76.74 165/215 nt 76.28 164/215 nt Homsap IGHJ2*01 F, or Homsap IGHJ4*01 F or Homsap IGHJ4*02 F or Homsap IGHJ5*01 F or Homsap IGHJ5*02 F (see comment) 22 75.0 6/8 nt 8 8 X 8.8.X [1.16.38.0] null + stop codons no junction found Low V-REGION identity (76,74% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*02 and Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides). The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag +3752 JY8QFUQ01CVHWF No results +3753 JY8QFUQ01DXHW7 unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F or Homsap IGHV1-69*01 F or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F 90 58.33 42/72 nt 56.94 41/72 nt X X X X.X.X [24.X.X.X] null - No rearrangement found in FR1-IMGT, from codon 7 of V-REGION: 3 nucleotides (from position 90 in the user submitted sequence), (do not cause frameshift) agttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgctctcggaggtgctcctggagcagggcgccagggggaagaccgatgggcccttggtggaggtgacgaagccaccagag +3754 JY8QFUQ01BJDTP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3755 JY8QFUQ01AMSEM No results +3756 JY8QFUQ01C3WCI No results +3757 JY8QFUQ01BSG5U unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 606 80.21 150/187 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD4-11*01 ORF 3 X 8 X X.8.X [X.16.38.11] DSRNPRV# out-of-frame + Low V-REGION identity (80,21% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) agtggggtccagccaggctccagggaaggggctggagtgggtctcagggctttgtggaagtgctcctaccacacactacgcagactccgtgaagggccggttcagcatctccagagacctctccaagaatgttctgtttctgcaaacgagcagcctgagagccgaggacacgaccgttttttctgactccagaaatcccagggtaggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3758 JY8QFUQ01CCRE0 No results +3759 JY8QFUQ01CBEL2 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +3760 JY8QFUQ01DISGH No results +3761 JY8QFUQ01BGWBK productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1046 97.29 215/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3762 JY8QFUQ01ASXQO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFD#PW out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggtttgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +3763 JY8QFUQ01A8ODQ No results +3764 JY8QFUQ01A4CAM unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +3765 JY8QFUQ01CB9SZ productive Homsap IGHV3-11*01 F 1003 96.3 208/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRWVWGYSYGSVSYYFEYW in-frame + tctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggctttcatacattagtggtagtggaactaccatatcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaggaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgaggtgggtgtggggatatagttatggttccgtttcgtactactttgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +3766 JY8QFUQ01CMDKZ No results +3767 JY8QFUQ01A8XAD No results +3768 JY8QFUQ01BB890 No results +3769 JY8QFUQ01C8BMK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDLYGADDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); acctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaAaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3770 JY8QFUQ01AMDD8 No results +3771 JY8QFUQ01C1UWI productive Homsap IGHV3-11*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame + ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggctttcatacattagtggtagtggaactaccatatactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +3772 JY8QFUQ01BEU4Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3773 JY8QFUQ01ARIHM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 88 of V-REGION: 'A' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); tctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtaAtctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +3774 JY8QFUQ01BQ0Z3 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 669 79.44 170/214 nt 78.97 169/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 74 of V-REGION: 'GG' (2 nucleotides at position 122 to 123 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactcccgtgagGGggtcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcgggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +3775 JY8QFUQ01AYPZ6 No results +3776 JY8QFUQ01DXB21 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 2 8 7 X 8.7.X [1.17.38.11] CARAPRTATLLDP#W out-of-frame + ctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgaccccgtggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3777 JY8QFUQ01A48DI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3778 JY8QFUQ01DSET8 unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*02 F or Homsap IGHV3-13*03 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-16*01 ORF or Homsap IGHV3-16*02 ORF or Homsap IGHV3-19*01 P or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-30*01 F 76 94.12 16/17 nt 5 X X 5.X.X [0.X.X.X] null + No rearrangement found tggattcaccttcaata +3779 JY8QFUQ01A4B73 unproductive Homsap IGHV3-72*01 F 1083 98.65 220/223 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYD#PG out-of-frame + ctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3780 JY8QFUQ01CK4S1 unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +3781 JY8QFUQ01AC05Z productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3782 JY8QFUQ01CAAYX No results +3783 JY8QFUQ01CI18Q unknown (see comment) Homsap IGHV3-16*01 ORF 88 53.1 60/113 nt 8 X X 8.X.X [25.4.X.X] null + No rearrangement found ctctggattcacctttagtagttctgccatgaactggaggagtctgggggaggcttggttcagccgggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +3784 JY8QFUQ01DO7RH unknown (see comment) Homsap IGHV3-52*01 P, or Homsap IGHV3-52*02 P or Homsap IGHV3-52*03 P or Homsap IGHV3-74*01 F or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 121 82.86 29/35 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found gtctggatttaccttcagtaagttctggatgcatt +3785 JY8QFUQ01A6FV3 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 418 87.85 94/107 nt 8 8 X 8.8.X [1.17.1.X] null + No rearrangement found ctctggattctccgtcagtaattactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcatacattagtaggagtagtactgacatatact +3786 JY8QFUQ01AOKPD No results +3787 JY8QFUQ01CWHMD No results +3788 JY8QFUQ01BS7EV No results +3789 JY8QFUQ01A2RKH unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F (see comment) 286 60.1 122/203 nt 10 9 X 10.9.X [2.17.29.X] null - No rearrangement found Low V-REGION identity (60,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release acctccggggacggtgtctctaccaacagtgctgcttggagttcgatcaggcagcccccatcgagaggccttgagtggctgggaaggacatactccgggtccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3790 JY8QFUQ01BSHEV unproductive Homsap IGHV3-9*01 F 797 85.32 186/218 nt 84.86 185/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CSKRHGRGSGTLVT#FDHW out-of-frame + in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); cctctggattcGacctttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtagtaaaagacatggtcgcgggtcagggactcttgtcacggttttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +3791 JY8QFUQ01DHJ01 unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3792 JY8QFUQ01CJT9B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDAVGLTRLFGDW in-frame + ctctggatttgtctttagtagatatgccatggcctgggtccgccaggctccagggcaggggctggagtgggtcgccagtattggcgggagtggtgataacacatactacgcggactccgtgaagggccggttcaccatctccagagacaactccaataacaaactgtttctgcaaatggacagtttgcgagccggggacacggccagatatttctgtgcgaaagatgcggtgggacttacccgactctttggtgactggggccagggaaccgtggtcagcgccgcctctgcatccccgacagccccaaaggtcttcccgctgagcctcgacagcacccccctcaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +3793 JY8QFUQ01DL9F7 unproductive Homsap IGHV1-18*01 F 1001 97.17 206/212 nt 95.28 202/212 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [0.16.37.11] CARDWYPNLEMATTLPFDY## out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'T' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 73 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift) tggttacacctttaTcgaactatggtatcagctgggtgcgacaggcCccctggacaagggcttgagtggatgggtggatcagcgcttacaatcataacacaactatgcacagaagctccagggcagagtcaccatgaccacagacacatccacgagcacagcctacatggaactgaggagcctgagatctgacgacacggccgtgtattattgtgcgagagattggtatcctaacctagagatggctacaaccctcccttttgactactggggccacgggaaccctggtcaccgtctcctctgcctccaccaagggccccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactccag +3794 JY8QFUQ01DEPU9 No results +3795 JY8QFUQ01AKUEW No results +3796 JY8QFUQ01AP6ET unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-59*08 F (see comment) 583 74.65 159/213 nt 74.18 158/213 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 7 7 X 7.7.X [1.17.38.X] null + stop codons no junction found Low V-REGION identity (74,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) ctttggtgtctccatctattgttctactgaagatggatccggcagcccccagaattgggactggagtggattggggatctctcttacagtgggaacaccaattacgacccctccctcaagagtcgagtcaccagatcaatagacacgtccaggaaacagttctccccgaacctcacactggggccagggaaccctgggcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3797 JY8QFUQ01ARD7M unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPGGNCLL*WW*#CYDPW out-of-frame + stop codons ctctgaattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggaattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3798 JY8QFUQ01AW5U8 productive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3799 JY8QFUQ01CF63C No results +3800 JY8QFUQ01DDWWQ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 179 60.48 75/124 nt 8 8 X 8.8.X [1.17.7.X] null - No rearrangement found stop codons ctctggattcaacttcaattattatagcatgagttgggtccgccaggctccgggaaagggactggagtgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3801 JY8QFUQ01CWJS5 productive Homsap IGHV3-7*03 F 1031 97.25 212/218 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDAFEMW in-frame - cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcaatgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3802 JY8QFUQ01BRSE6 productive Homsap IGHV3-9*01 F 820 86.3 189/219 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD5-24*01 ORF 3 8 8 17 8.8.17 [2.17.38.11] CVKDRKAGGYNLLDAFDIW in-frame - gcctctggattcaccttcgacgactatgtcatgcattgggtccggcaagttccagagaggggcctggagtgggtcgcaggcattaatggggaaagtaatagttttggctctgtggactctgtaaagggccgattcaccatctccagagacaaggccaagaataccctgtatttgcaaatgaatagcctgagagttgaggacacggccttgtattattgtgtgaaagatagaaaagctggtggctacaatctgttggatgcttttgatatctggggccaagggacaatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3803 JY8QFUQ01AO2QK No results +3804 JY8QFUQ01A13MR productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAREDGSGRRHFDYW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccaggaaagggactggagtggattgggtatatcttttacactaggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3805 JY8QFUQ01AT9NZ unproductive Homsap IGHV3-7*01 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [0.17.38.11] CVRGRDGVNFGEMDY## out-of-frame - in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctgggttcatctttagtagacattggatggcctgggtccgccaggctccagGggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactgggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3806 JY8QFUQ01DBU2R productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 871 89.72 192/214 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccntgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3807 JY8QFUQ01CC515 productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F (see comment) 778 84.72 183/216 nt 84.26 182/216 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD2-8*01 F 2 8 8 12 8.8.12 [1.17.38.11] CAGETSSTFYFESW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); tggaaaacacctttcgtcaactaccttatacactgggtgcgacaggcccctggtcaagggcCttgaatggatggggtgtatcaaccctagtgacccttacacaaactacgcacagaagttccagggcagactcaccatgaccggggacacgtccacgaacacagtctacatggagctgagcagcctgagatctgaggatgcggccgtgtattactgtgctggagagacatcctctacattctactttgagtcctggggccagggaaccttagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtgatcgtcgcatgcctggtccagggcttcttccccca +3808 JY8QFUQ01C4A6Q No results +3809 JY8QFUQ01DA6FV No results +3810 JY8QFUQ01CF194 No results +3811 JY8QFUQ01C0VVG unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 262 62.2 102/164 nt 8 10 X 8.10.X [1.17.20.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (10 AA in JY8QFUQ01C0VVG ; 8 AA in Homsap_IGHV3-7*01), and low V-REGION identity (62,20% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcactttcactaacgcctggatgagctgggtccgccaggctccagggaaggggctggagtggattggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3812 JY8QFUQ01CABKE No results +3813 JY8QFUQ01AX2TW unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 639 76.96 167/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (76,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3814 JY8QFUQ01A2SRW productive Homsap IGHV3-13*01 F 981 94.93 206/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame - agcctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3815 JY8QFUQ01B7SLG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASDLGGQKSYW in-frame - ctcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3816 JY8QFUQ01BKOGA unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 112 53.73 72/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3817 JY8QFUQ01CMDGF No results +3818 JY8QFUQ01AZB12 No results +3819 JY8QFUQ01DPR9B No results +3820 JY8QFUQ01A7Y0G No results +3821 JY8QFUQ01CK8G7 No results +3822 JY8QFUQ01DV1ZT No results +3823 JY8QFUQ01B6HOD productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 709 81.69 174/213 nt 81.22 173/213 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.37.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 119 in the user submitted sequence), (cause frameshift) ctctgggttcaccatcactcactactccatggcctgggtccgccaggctccggggaaggggctggagtgggtctcattgatttatcccggcgggagcacattccacgcagactccgtgaggggcgcctcatcatctccagagacgagtccaagggtgaggtgtatcttcggatgacgagggtgaaaaccgaagacgcggccgtgtattactgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtctctgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +3824 JY8QFUQ01BG5LR productive (see comment) Homsap IGHV3-7*03 F 819 86.64 188/217 nt 85.71 186/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 8 12 8.8.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); ctccggattcacattcagtaattattggatgagctggatccgccagactccagggaggggcgtggagtAgggtggccaacataaagtacgatggaggtgaagaatactttgcggactctgtgaggggccgagccaccatctccagggacaacaccaaaaaTttctctttatctgcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtccgtcgcatgcctggtc +3825 JY8QFUQ01BQ8KG No results +3826 JY8QFUQ01ALPIB No results +3827 JY8QFUQ01BL7OE No results +3828 JY8QFUQ01C6BX0 productive Homsap IGHV3-66*02 F 876 90.19 193/214 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD3-16*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAALHDPPWGWLDPW in-frame + ctctggattcagcgtcaacaacaactacatgaactgggtccgcctggctccagggaagggtctggagtgggtctcagttatttatagaggtggtaatacattctacacagactccgtgaagggccggttcaccatctccagagacatttccaagaacactttgtatcttcaaatgaacagtctgacaactgaggacacggctgtgtactattgtgcggccctccacgaccctccttggggttggctcgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3829 JY8QFUQ01CR7CX productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 7 12 8.7.12 [1.17.38.11] CARAPGWMNPFDFW in-frame + tctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3830 JY8QFUQ01ATWJQ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEEVWYGSGRGGPK#DYW out-of-frame + in CDR2-IMGT at codon 59 of V-REGION: 'GGA' (3 nucleotides at position 89 to 91 in the user submitted sequence), (do not cause frameshift); ctctggattcacctttaggagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtGGAaatgttgatagcacagactacgcagattccgtgaagggccggttcaccatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaaagaagaagtgtggtatggttcggggagaggggggcccaaaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +3831 JY8QFUQ01AUMS2 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttactggatgcactGgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccttgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +3832 JY8QFUQ01CQOIV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 738 82.49 179/217 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDKAGFTLHAFDVW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttgccagccacgccatggcttgggtccgccggactccaaggaagggcctggagtgggtctcaggcataagtagtagtggtggaaccacgtattacgcagacttcgtgaagggccgcgccactgtctccagagacaattccgagaacacagtgtctctggaactccacagcctgagagccgatgacacggccatatattattgtgtgaaggacaaagcgggcttcaccctccatgcttttgatgtctggggccgagggacggtggtcactgtttcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3833 JY8QFUQ01DDBEG No results +3834 JY8QFUQ01B5HXY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDVSTRITMRVVVPALDYW in-frame + gtctggattcacgtttagaaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattagtgataatggtgacagcatattccacgcagactccgtgaagggccggttcaccatcaccagagacaactctaagaacatcctgtatctgcacatgaacagcctgagagccgaggactcggccgtatattactgtgcgaaggatgtttccacgcgtattactatgagagttgtggtgccagcccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +3835 JY8QFUQ01DGQGM productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F (see comment) 121 66.13 41/62 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGFNFGEMQYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaccataaaccaagacggaagtcggagacactttgtggactctgtggagggccgattcagcatctccagagacagcgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgtgaggggtagagatggcttcaacttcggcgaaatgcagtactggggccagggagccccggtcagcgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3836 JY8QFUQ01CS7JW productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 696 80.84 173/214 nt 80.37 172/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 78 of V-REGION: 'AG' (2 nucleotides at position 135 to 136 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcgaAGtctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3837 JY8QFUQ01DTUHV No results +3838 JY8QFUQ01B1E0J No results +3839 JY8QFUQ01CED09 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 447 93.14 95/102 nt 8 7 X 8.7.X [1.17.X.X] null - No rearrangement found cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgaca +3840 JY8QFUQ01B4NF6 unproductive (see comment) Homsap IGHV3-7*01 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.16.38.11] CATSPYGDYWEGR#YW out-of-frame - stop codons in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 78 in the user submitted sequence), (cause frameshift) cctctagatcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +3841 JY8QFUQ01CH02B productive Homsap IGHV3-11*01 F 828 87.1 189/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CVREVTGVWDWFDPW in-frame + ctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3842 JY8QFUQ01A0D2K productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3843 JY8QFUQ01CUE1Y productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-25*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARHEGYNSRYYYFGYW in-frame + ttctggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3844 JY8QFUQ01C559L unproductive (see comment) Homsap IGHV3-7*01 F (see comment) 423 65.9 143/217 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt Homsap IGHD7-27*01 F 3 8 8 2 8.8.2 [1.17.38.6] NR*R in-frame + stop codons Low V-REGION identity (65,90% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3845 JY8QFUQ01ANMGM No results +3846 JY8QFUQ01B6WTL No results +3847 JY8QFUQ01CBJ3P productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3848 JY8QFUQ01A444V No results +3849 JY8QFUQ01B1G48 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 869 88.99 194/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ggcctcctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3850 JY8QFUQ01BZZFO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCGNGACHVADYW in-frame + ctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatcccctggaccagccccaaggctcttccgctgagcctccgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +3851 JY8QFUQ01DNBP1 No results +3852 JY8QFUQ01BP2VQ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) cctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3853 JY8QFUQ01BXOZU unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +3854 JY8QFUQ01CVHT1 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 104 52.94 72/136 nt 8 8 X 8.8.X [2.17.10.X] null - No rearrangement found stop codons gcctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3855 JY8QFUQ01B7NMF No results +3856 JY8QFUQ01BC4J6 No results +3857 JY8QFUQ01BLZAU No results +3858 JY8QFUQ01C1T5U No results +3859 JY8QFUQ01BJ353 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.16.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaagggctggagtgggtctccggtattggtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3860 JY8QFUQ01A1V7G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDLALGGGSCWHYW in-frame + ctctggattcacctttagcagatatgccatgacctgggtccgccaggctccagggaagggactggagtgtgtctcagctattagtggtgatggcgctaacacattctacccaagttccgtgaagggccggttcaccatctccagagacaattccaagaacacgctatatctgcagatggacagcctgagagccgaagacacggccgtatattactgtgcgaaagatctggcgttgggtggtggtagctgctggcactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcca +3861 JY8QFUQ01DHBP6 unproductive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ6*01 F (see comment) 94 61.29 38/62 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSGYYSTGY# out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ1*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3862 JY8QFUQ01ADM37 No results +3863 JY8QFUQ01CNW28 productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +3864 JY8QFUQ01AQ8FC productive Homsap IGHV4-39*03 F 929 91.36 201/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3865 JY8QFUQ01BSGAY productive (see comment) Homsap IGHV4-61*02 F 893 89.59 198/221 nt 89.14 197/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 104 of V-REGION: 'C' (1 nucleotides at position 220 to 220 in the user submitted sequence), (cause frameshift); tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttCgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaact +3866 JY8QFUQ01CO2BZ No results +3867 JY8QFUQ01BIC0A unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*05 F 178 55.68 98/176 nt 8 7 X 8.7.X [1.17.25.X] null + No rearrangement found ctctgcattcaccttcagtagctacgacatgcactgggtccgccaagcaacaggaagaggtctggagtgggtctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3868 JY8QFUQ01A0V1E productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 864 88.94 193/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 8 8 20 8.8.20 [1.17.38.11] CTRTQFDPDYGDYETGYGMDVW in-frame + ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagacaattccaagaacacattgtttctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtacgaggacgcaatttgaccctgactacggtgactacgagacggggtacggtatggacgtctggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +3869 JY8QFUQ01C8AF9 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P 134 55.64 74/133 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcatcttcagtgactactacatgacctggatccgccaggctccaaggtcttcccgctgagcctcgacagccacccccgaagatgggaacgtgtcgtcgcatgcctggtccagggcttcttccccc +3870 JY8QFUQ01B5NZK unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 943 93.9 200/213 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD6-13*01 F 2 8 7 X 8.7.X [1.17.38.11] CARGVGQQLPP*#W out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctagtggctccatcaatgcttactactggagctggatccggcagtccccggggaagggactggagtggatgggatatatctatgacagtgggagcaccaactacaacccctccttcaagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtttattactgtgcgagaggggtggggcagcaactgcccccttagagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc +3871 JY8QFUQ01C7KW5 No results +3872 JY8QFUQ01BCTSU No results +3873 JY8QFUQ01AVO0G productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 845 90.29 186/206 nt 89.81 185/206 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 9 nucleotides (from position 15 in the user submitted sequence), (do not cause frameshift) tctctggtgactctcacttctggagctggatccggcagcccccagggaagggcccggagtggattggttatgtttataacagtgggaccaccaactacaacccctccctcaggagtcgagtcaccatttctatcgacacgtccaagaagcagatctccctgaagttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3874 JY8QFUQ01CPKQV unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 80 51.13 68/133 nt 8 6 X 8.6.X [1.17.12.X] null + No rearrangement found ctctggattcacctttggcagctatatcatgagctgggtccaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3875 JY8QFUQ01APVVP productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDMIIFGGALDNW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggagcccttgacaactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3876 JY8QFUQ01BHWUR No results +3877 JY8QFUQ01DW734 No results +3878 JY8QFUQ01B8OTM No results +3879 JY8QFUQ01C9T80 No results +3880 JY8QFUQ01AOUC3 unknown (see comment) Homsap IGHV3-11*01 F (see comment) 746 83.26 179/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctggattcaccctcagtgactacagtatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatacatcagccgaagtggaagtaatgtggaaactgcggactctgtgaggggccgattcaccgcctccagggacaccgccaataattcactgtttctgcggatgaatagcctgacagtcgaggacacggccctctattactgtgcgagagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3881 JY8QFUQ01ADQHC unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 103 52.99 71/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3882 JY8QFUQ01CFBFI productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 9 7 12 9.7.12 [1.17.38.11] CAANLGHGSYFKYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtgactccgtcagcagtgataactggtggaGgttgggtccgccagaccccagggaaggggctggagtggattggagaaatctatcatggtgggaccaccaactacaatccgtccctcaagggtcgagtcaccttatcggtcgacaagtccaagaaccaattctctctgagaatgacctcttttaccgccgcagacacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3883 JY8QFUQ01DGVL6 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 900 90.78 197/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + gtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3884 JY8QFUQ01CO7LQ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc +3885 JY8QFUQ01DELV5 productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3886 JY8QFUQ01AJ9A6 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F (see comment) 756 83.41 181/217 nt 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-6*01 F 1 8 7 12 8.7.12 [1.17.38.11] CVRSYSRTSEFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) cgtctggattcagttcagtaccctttggcatgagttggatccgccagacgccaggcaaggggctggagtgggtgacagttatatggtcggatggactcaaaaaaattatgcagactccgtgaagggccgattcaccatctccagagacaatgtcaagaacacggtttatttgcagatgagcagcctgagagtcgaggacacgggcgtatattattgtgtgaggtcgtatagtaggacatctgagtttgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3887 JY8QFUQ01AMH2G No results +3888 JY8QFUQ01A3RHO No results +3889 JY8QFUQ01BEVNG unknown (see comment) Homsap IGHV5-51*05 F 156 52.94 108/204 nt 8 8 X 8.8.X [X.17.38.X] null + No rearrangement found stop codons ggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3890 JY8QFUQ01ABTRX No results +3891 JY8QFUQ01A8ALV productive Homsap IGHV3-48*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDRGGSAYPIFDYW in-frame + tctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3892 JY8QFUQ01ATUS3 No results +3893 JY8QFUQ01BIDT5 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 796 85.65 185/216 nt 84.72 183/216 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.16.38.11] CARDSGSSEYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) ctctgggattcagcttaagttcttatggcatgaactggtccgccagcgtccatgggggggctggagtgggtctcattcattaacagtattagtagttataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3894 JY8QFUQ01DEI6W No results +3895 JY8QFUQ01BJ183 No results +3896 JY8QFUQ01B63PV productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*03 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 103 62.9 39/62 nt Homsap IGHD5-12*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDQRDYDYIYYYGMDLW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 83 of V-REGION: 'T' (1 nucleotides at position 152 to 152 in the user submitted sequence), (cause frameshift); ctctggattctccctcaggaatcatgctatgcactgggtccgccagactccaggcaagggactcgagtgggtggcagttatctcatttaatggacgaaggaagtattatgcagacttcgtgaagggccgattcaccatcaccagggacaatTtcccagaacactctgtctctgcaattgaatagcctgggaactgaggacacggctgtctattactgtgcgagagatcagcgtgactacgattacatctactattacgggatggacctctggggccaaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttccgctgagcctctgcgcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +3897 JY8QFUQ01AFS6I unproductive (see comment) Homsap IGHV3-7*01 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDPRSVSRYSLFDSW# out-of-frame - stop codons in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 214 to 214 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtgactattggatgagctgggtccgccaggctccagggaaggggctagagtgggtggccaacataaaataGagatggaagtgagcaacactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacatggctatgtatTttttgtgcgagagatcctcgttccgtgagcaggtactctttatttgactcctgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3898 JY8QFUQ01B2UFO productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagccCcgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3899 JY8QFUQ01ATJND No results +3900 JY8QFUQ01BNYIU productive (see comment) Homsap IGHV4-61*02 F 897 90.0 198/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.16.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) tctccggtggctccatcagtactggttattactactGggagctggatccggcagtccgccgggaagggactgaatggattgggcgcatgtctgccagagggggAcagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3901 JY8QFUQ01ATMYD productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +3902 JY8QFUQ01AX0UJ No results +3903 JY8QFUQ01DVMEJ No results +3904 JY8QFUQ01A9KHI productive (see comment) Homsap IGHV1-2*02 F 921 92.52 198/214 nt 91.59 196/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARWGATWELLLGNLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); tggatacacgttcaccgactactatgtccactgggtgcgacaggAcccctggacaagggcttgagtggatggcgtggatcaaccctaacattggtgtcaccaagtctgcacGaaaaatttcagggcagggtcaccatgaccagggacacgtccatcagcacagccttcatggagctgagcagcctgagatctgacgacacggccgtttattactgtgcgagatggggggcgacgtgggaactattattggggaatcttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3905 JY8QFUQ01BR91W No results +3906 JY8QFUQ01AT5T6 No results +3907 JY8QFUQ01CNIKN unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*03 F or Homsap IGHV3-48*04 F (see comment) 327 64.97 115/177 nt 64.41 114/177 nt 7 8 X 7.8.X [1.17.25.X] null - No rearrangement found Low V-REGION identity (64,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) tctggattcaccttcactagaagtccatgaattgggtccgccaggctccggggaaggggctggaatgggttgcatacattagtagtgatggtagtaccctatactacgcagactctgcagcacccagccagatgggaacgtggtcatcacctgcctggtccagggcttcttccccca +3908 JY8QFUQ01BZUY8 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + ctctggattcagcttcagtacctataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3909 JY8QFUQ01AT14G productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 7 8 15 7.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) ttctggattcagtcctaccgattttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccatccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +3910 JY8QFUQ01DTNQN unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CANELGYCSGA## out-of-frame - in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 121 to 121 in the user submitted sequence), (cause frameshift); tctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgAaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgcgggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3911 JY8QFUQ01C9728 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +3912 JY8QFUQ01A5RXF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [2.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); ccctctggattcaccttcagtacatactggatgcactgggtccgccCaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccaattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3913 JY8QFUQ01A24L7 productive Homsap IGHV1-24*01 F (see comment) 279 66.91 91/136 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD3-16*01 F 2 X 7 8 X.7.8 [X.X.38.11] CARRSVLDIW in-frame + Low V-REGION identity (66,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacgcgttcagaaatcatgacattaactggaagtttcagggcagagccaccatgaccagggatacgtccacagatacagcctatttagaagtgaacggcctgggacctgaggacacggccgtgtattactgcgcgaggcggagtgttcttgatatctggggccaaggaacaagggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3914 JY8QFUQ01C0P9U productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +3915 JY8QFUQ01B1GX5 unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD5-24*01 ORF 1 8 7 9 8.7.9 [4.17.38.11] CARGAPFS**C in-frame + stop codons ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +3916 JY8QFUQ01BLTOE No results +3917 JY8QFUQ01A4IGN productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +3918 JY8QFUQ01C15AT unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.37.11] CANEVGYCSGG# out-of-frame - in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtgggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +3919 JY8QFUQ01DKID1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3920 JY8QFUQ01DFWGJ unknown (see comment) Homsap IGHV1-NL1*01 P 84 56.41 44/78 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccaga +3921 JY8QFUQ01BSY1C productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.17.38.11] CARGEMTAEYYFDYW in-frame + tctctggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3922 JY8QFUQ01A4005 No results +3923 JY8QFUQ01BVLE3 unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggaacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3924 JY8QFUQ01CC9XC productive Homsap IGHV3-21*04 F 963 94.01 204/217 nt Homsap IGHJ6*01 F 252 88.89 56/63 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [1.17.38.11] CVRYWGSYYYYNGLDVW in-frame + ctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtttctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgagatattggggcagctactattactataacggtctggacgtctgggggcaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3925 JY8QFUQ01DF6AO No results +3926 JY8QFUQ01DVYEJ No results +3927 JY8QFUQ01BHN92 No results +3928 JY8QFUQ01CHC60 productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1022 94.71 215/227 nt 94.27 214/227 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 9 9 14 9.9.14 [2.17.38.11] CARGGNYYDSGGLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) atctccggggacagtgtctctagcagcagtgttgttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcgaataactatcaagccagacgcatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtatattactgtgcaagagggggtaattactatgatagtggtggtcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3929 JY8QFUQ01DJCKC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKDLGLVGATGLDYW in-frame + ctctggattcacctttcgcagatatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattaataatagtggtggtagcacatactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcaactgagcagcctgagagccgaggacacggccatgtatttctgtgtgaaagatctgggactagtgggcgctactgggctggactactggggccagggaacccgggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccggctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3930 JY8QFUQ01AFD8Y No results +3931 JY8QFUQ01AT4CD No results +3932 JY8QFUQ01C7LJW productive (see comment) Homsap IGHV4-4*07 F 782 85.12 183/215 nt 83.72 180/215 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 8 7 18 8.7.18 [1.17.38.11] CAREDYYGSGSYGRAWFDSW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'CAGTGG' (6 nucleotides at position 20 to 25 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); tctctggaggctccatcagCAGTGGaagttactactggacctggatccggcagcccgccgggaagactctggagtggatTtgggcgcttctacagtcgtCgggggtgtcgactacaacccctccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggctgtgtatttctgtgcgagagaggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3933 JY8QFUQ01CQWKF productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 7 8 13 7.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) tctggattcaactcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3934 JY8QFUQ01BRC8T No results +3935 JY8QFUQ01CMMDZ No results +3936 JY8QFUQ01B2SZG unproductive (see comment) Homsap IGHV3-7*01 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKGGW*R##LDYW out-of-frame - stop codons in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); acctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3937 JY8QFUQ01BUJLR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ6*02 F (see comment) 188 78.69 48/61 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CAREGGRGYDMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtgcgagagaggggggacgtggctacgatatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +3938 JY8QFUQ01DPX3I No results +3939 JY8QFUQ01B3ZD4 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 981 94.93 206/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccaggggaaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3940 JY8QFUQ01DW3GZ No results +3941 JY8QFUQ01DEEDN productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAKDFYYGCDYW in-frame + ctctggattcaacttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagtcattgcatacaatggaggaaatatatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaaggataccctgtacttgcacatgaccagtctgagacctgatgacacggccatgtattactgtgcgaaagacttttattatggttgcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +3942 JY8QFUQ01AW2Y4 productive Homsap IGHV3-11*01 F 1044 98.16 213/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARVVGATLYYFDYW in-frame + ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtgttagtgccatatactacgcagactctgtgaagggccgattcaccatctccagggacaacgcccagaactcactgtatctgcaaatgcacagcctgagagccgaggacacggccgtgtattactgtgcgagagtagtgggagctaccctgtactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3943 JY8QFUQ01B2VIG productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 924 91.36 201/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 10 7 11 10.7.11 [1.17.38.11] CARSYGFSRFDPW in-frame + ctctggtggctccatcaccagtagtctttaccgctggggctggatccgccagtccccagggaagggcctggagtggatagggaatatcttttatggtgggaccacctactacaacccgtccctcaagagtcgagtcaccttatccatagacacgtccaagagccagttctccctgaagctgtcctctgtgaccgccgcagacacggctctatattactgtgcgagatcgtacggtttctctcggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3944 JY8QFUQ01BOS92 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAREASNGNYNLVFDYW in-frame + gtctggattcaccttcagtgaccatgccatgcactgggtccgccaggctccaggcaaggggctggagtcggtggcagttatatggtatgatggaagtaataaactttatgcggactccgtgaagggccgcttcaccatctccagagacaattccaagaacatgctgtatctgcagatgagcagcctgagagccgaagacacggctgtgtatttctgtgcgagagaagcctctaatgggaactacaacctcgtctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3945 JY8QFUQ01CUM4N productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 8 8 10 8.8.10 [1.17.38.11] CATWIQSHFDYW in-frame + ctctggattcacatttagtcactataccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagccattaatcaagatgccattaccacacactacccagactccgtgaagggccgcttcaccgtctccagagacaattccaagaacacactctatctgcaaatgagcagcctgagagccgacgacacggccgtatattattgtgcgacgtggatacagtctcactttgactattggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3946 JY8QFUQ01B74LF unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3947 JY8QFUQ01CQ64D No results +3948 JY8QFUQ01CAGK7 No results +3949 JY8QFUQ01A5U3W productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgagaacgtggtcatcgcctgcctggtccagggcttcttccccca +3950 JY8QFUQ01AGNL8 productive (see comment) Homsap IGHV3-7*03 F 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [0.17.38.11] CTRRGFMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctggattcaccttcaggagctattggatgagctgggtccgccaggctccagGggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3951 JY8QFUQ01C9A0A productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +3952 JY8QFUQ01CU1O9 No results +3953 JY8QFUQ01BCYGH No results +3954 JY8QFUQ01BW5IP productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 859 95.24 180/189 nt 94.18 178/189 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.7.37.11] CVRSEYSSSNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 28 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 77 of V-REGION: 1 nucleotides (from position 108 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagctatagaatgaactggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcacatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca +3955 JY8QFUQ01BZ3ER unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 95 100.0 19/19 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found tctggattcacctttagta +3956 JY8QFUQ01BX34R productive Homsap IGHV3-9*01 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDKGGSNWKYFDLW in-frame + ctttggattcaagtttgatgattatgccatgcactgggtccgacaagttccagggaagggcctggagtgggtctcaagtataagttggggtagtaggaccatagtctatgcggactctgtgaaggaccgattcaccgtctccagagacaacatcaggaagtccctctatctgcaaatggacagcctgagacctgacgacacggccctctattactgtgcaaaagacaagggcggcagcaactggaaatactttgacctctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3957 JY8QFUQ01CJSXO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVAVGMSGWFDPW in-frame + ctctggattcaccttcagtgggtcttggatgcactgggtccgccaagctccagggaaggggctggtgtgggtttcacgtattaatcgtgatggcagtagcacaagctacggggactccgtgaagggccgattcaccgtctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgcgagtcgacgacacggctctatattattgtgcaagaggccgtatagtagcagttgggatgtcaggctggttcgacccttggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3958 JY8QFUQ01DDNJZ No results +3959 JY8QFUQ01A1BIU No results +3960 JY8QFUQ01A5ZKW productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 930 91.03 203/223 nt 90.58 202/223 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 10 14 8.10.14 [1.17.38.11] CTTRPRGWEPLGLDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 128 to 128 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatggtctgggtccgccaggctccagggaaggggctggagtgggttggccttattaagaccaaacctgatggttggacaacaatctactctgcacccgtgAaaaggcagattcatcatttcaagagatgattcaaaaaacatggtgtttctgcaaatgaacaacctgagaaccgaggacacagccctttattactgtaccacacggccccgggggtgggaaccacttggccttgactactggggcctgggaaccctggtcaccgtctcctcagcatccccggaccagccccaaaggtcttccccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3961 JY8QFUQ01DEIMF No results +3962 JY8QFUQ01DE72N productive Homsap IGHV4-34*06 F (see comment) 701 80.84 173/214 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 14 8.7.14 [1.17.38.11] CSRGGQSAGWHSFEAW in-frame + Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tccatggtgggtccctcaggggttacccctggacctggatccgccacaccgcagagaagggactggagtggattggtcaaatcaatagtgatggaaggacaacctacaactcggccctcatgggtcgagtcaccatttcaacagacacatccaagaatcagttctcgctgactgtggtttctgttgtcgccgcggacacggcaatgtattattgttcgagaggaggccaaagtgctggctggcactcctttgaagcctggggccagggaacccaggtaatcgtcacctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +3963 JY8QFUQ01DI5ZW unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 998 96.28 207/215 nt 95.35 205/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.16.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaagggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccaggggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3964 JY8QFUQ01CEUVW No results +3965 JY8QFUQ01BS8OE productive (see comment) Homsap IGHV3-11*01 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD2-21*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARGKMVSTGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 96 of V-REGION: 'G' (1 nucleotides at position 192 to 192 in the user submitted sequence), (cause frameshift); gctctggattcacgtttagtgactactacatgacctggattcgtcaggctccagggaagggcctggagtgggttacatatattagtagtagtggtggtaacacacattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaacgcactgtatctgcaaatgaacagcctgaggGgccgaggacacggccgtgtattactgtgcgcgagggaagatggtgagcaccggtatggacgtctggggccaagggaccacggtcgccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3966 JY8QFUQ01CLT9N No results +3967 JY8QFUQ01AJ6YX No results +3968 JY8QFUQ01C8XBU No results +3969 JY8QFUQ01AEKWU productive Homsap IGHV3-48*02 F (see comment) 719 81.4 175/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [0.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3970 JY8QFUQ01AJCMG productive (see comment) Homsap IGHV3-11*01 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ6*02 F 263 94.83 55/58 nt Homsap IGHD1-26*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDYYYYGMDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'GGG' (3 nucleotides at position 95 to 97 in the user submitted sequence), (do not cause frameshift); ttctgggttctccttcagcgactacttcatgagttgggtccgccaggctccagggaagggactggagtgggttgcatacattagtagtagtggtGGGactactaaatactacgcagactctgtgaagggccgattcaccatctccagggacaacggcaagaattcattgtttctgcaaatggacagcctgagagtcgacgacacggccatgtatttctgtgtgagagactactattattacgggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttcccccag +3971 JY8QFUQ01BR4UW unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 231 57.81 111/192 nt 8 8 X 8.8.X [1.17.30.X] null + No rearrangement found Low V-REGION identity (57,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +3972 JY8QFUQ01C77T7 No results +3973 JY8QFUQ01A21B3 No results +3974 JY8QFUQ01DURUL productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-NL1*01 F 844 88.73 189/213 nt 88.26 188/213 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [1.17.38.11] CTRELRVAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggGggctggagtgggtctcagtaatttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +3975 JY8QFUQ01CIVDS No results +3976 JY8QFUQ01B933L productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3977 JY8QFUQ01DSZ8R No results +3978 JY8QFUQ01BHZCF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +3979 JY8QFUQ01C4JWB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.37.11] CARRTITAAGRGDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 132 in the user submitted sequence), (cause frameshift) cctctgaattcacctttagcagAttttgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagcattggtactagtgttgttaacacatggtacgcagactcagtgaagggccggtcgccatttccagagacaattccaagagcacgctgtatttgcaaatgaatagcctgagagtcgaggacacggccgtatattactgtgcgaggaggacaataacagcagctggccgtggggatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3980 JY8QFUQ01BNKOY No results +3981 JY8QFUQ01AS6KG No results +3982 JY8QFUQ01AMWVF productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARPGVGASSFIDFW in-frame + ttctggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +3983 JY8QFUQ01B0OXJ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + ctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3984 JY8QFUQ01DENNK No results +3985 JY8QFUQ01A5C0K No results +3986 JY8QFUQ01CCIHD No results +3987 JY8QFUQ01BOCYN No results +3988 JY8QFUQ01DMKY7 No results +3989 JY8QFUQ01BZ1D4 productive Homsap IGHV3-7*03 F 832 87.5 189/216 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tccggattcacttttagtgactattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3990 JY8QFUQ01CGNEG unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +3991 JY8QFUQ01AL3H2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ3*02 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDRMIHTMRG#FDMW out-of-frame - cctctggattcaccttcagaaccaatgccatgaactgggtccgccaggctccagggaaggggctggagtggatctcagttattaatggtcccggtgatatcacatactacgcagactccgtgaagggccggttcaccatgtcccgagacaattccaaggacacgttgtatttgcaaatgatcagcctgagaggcgaggacacggccatatattactgtgcaaaagatcgtatgatacacacgatgaggggagctttgatatgtggggccgagggacaatggtcaccgtctcttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +3992 JY8QFUQ01A0GSS No results +3993 JY8QFUQ01B6AJY No results +3994 JY8QFUQ01BPA4Z No results +3995 JY8QFUQ01AIKEQ No results +3996 JY8QFUQ01DB2BI No results +3997 JY8QFUQ01CYCIU No results +3998 JY8QFUQ01AROLJ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 89 51.88 69/133 nt 8 6 X 8.6.X [1.17.12.X] null - No rearrangement found ctctggattcaccttcagctcccattggatgagctgggtccgccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +3999 JY8QFUQ01C35HE No results +4000 JY8QFUQ01DMY5F unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggcccaggggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccttggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4001 JY8QFUQ01AZQGR unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*05 F 948 91.93 205/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 3 8 10 X 8.10.X [1.17.38.11] CVVDIPEVGVGA#FDYW out-of-frame + stop codons ctctggattctctttcacttatgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttgcccttattaaaagcaaaactagtggtgggacaacacactacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcagagaacacgttctatctacaaatgaatagactgaaaaccgaggacacagccgtgtattattgtgtcgtagatataccagaagttggtgtgggggcaatttgactactggggccagggagccctggtttccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgatcatcgcctgcctggtccagggcttcttccccca +4002 JY8QFUQ01DRHQR No results +4003 JY8QFUQ01C10GW unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 442 93.07 94/101 nt 8 7 X 8.7.X [1.17.X.X] null + No rearrangement found ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgaca +4004 JY8QFUQ01AYXGF No results +4005 JY8QFUQ01BGU6I unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 474 82.61 114/138 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (82,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc +4006 JY8QFUQ01BZPQW No results +4007 JY8QFUQ01BLGYX productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 894 91.12 195/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-1*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARRQLALAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); tggatacacctttatcacctactggatcgcctgggtgcgccaaatgcccgggaaAaggcctggagttgatgggagtcatctatcctggtgactctgagaccagatacagcccgtCccttccaaggccacatcaccctctcagtcgacaagtccatcgataccgcctacctggagtggagcagcctgaaggcctcggacaccgccatgtacttctgtgcaagaagacaactggcccttgcctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4008 JY8QFUQ01B3Q8U No results +4009 JY8QFUQ01BNVNO productive (see comment) Homsap IGHV3-74*03 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 7 14 8.7.14 [1.17.38.11] CAKVDSDGWHGTIDRW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggatagcgatggctggcacggaacaatagaccgctggggccagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4010 JY8QFUQ01BMI6W productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggGcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4011 JY8QFUQ01C4WW4 productive Homsap IGHV3-9*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + ctctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4012 JY8QFUQ01AV66V No results +4013 JY8QFUQ01ADD8V productive Homsap IGHV3-11*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame + ctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +4014 JY8QFUQ01DC351 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 468 68.2 148/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (68,20% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4015 JY8QFUQ01B30JH No results +4016 JY8QFUQ01C0RZ5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + ctctggattcactttcagtagctactggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4017 JY8QFUQ01DQS4M No results +4018 JY8QFUQ01AF1GF No results +4019 JY8QFUQ01CCM2W No results +4020 JY8QFUQ01AP8KN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 845 88.37 190/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [0.17.38.11] CVKGWNYHSATFGFDYW in-frame + ctggattcacctttagtgactatgccataagctgggtccgccaggctccaggaaaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccattttcagagacaactccaaagacacgctgtatctgcaaatgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaacctttgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4021 JY8QFUQ01DUEJN productive Homsap IGHV3-33*04 F (see comment) 688 80.09 173/216 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame - Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release attggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4022 JY8QFUQ01B4TSY unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 918 91.71 199/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 97 66.0 33/50 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CARRDVGLHAFDL## out-of-frame + ttctggatccaattttaactacgactggatcggctgggtgcgccagatgcccggtaaaggcctggagtggatgggaatggtctatgttggtgactctgatgctagatacagcccgtcctcccaaggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgcttttgatctgtggggcccaggggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4023 JY8QFUQ01AHN2J No results +4024 JY8QFUQ01A6E0M productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [0.17.38.11] CVREGRGTAAYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 92 of V-REGION: 'A' (1 nucleotides at position 177 to 177 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgAaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4025 JY8QFUQ01BUEWQ No results +4026 JY8QFUQ01A80I1 unproductive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*04 F or Homsap IGHV3-49*05 F 1083 98.65 220/223 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 8 10 X 8.10.X [1.17.38.11] CTPWWRGGYFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ttctggattcacctctggtgattatgctatgagctggctccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaaccatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtaccccgtggtggcggggaggttactttgactactgggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +4027 JY8QFUQ01CAW1S productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 959 93.58 204/218 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 14 8.8.14 [1.17.38.11] CATDRKYSGVRGDDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcaggaactatgctatgcactgggtccgccaggctcctggcaaggggctagaatgggtggcttttatatcatatgatggaagtagtcaatactacgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacactttatctgcaaatgaacagcctgagaggtgacgacacggctgtgttttactgtgcgacggaccggaaatatagtggtgtacgaggcgatgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4028 JY8QFUQ01CST6S productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4029 JY8QFUQ01DAV14 unknown (see comment) Homsap IGHV3-48*03 F 873 89.4 194/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4030 JY8QFUQ01COVOC No results +4031 JY8QFUQ01A1LZR No results +4032 JY8QFUQ01BIUX6 unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 674 94.04 142/151 nt 8 8 X 8.8.X [1.17.16.X] null + No rearrangement found ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaat +4033 JY8QFUQ01C238V productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4034 JY8QFUQ01C9757 productive Homsap IGHV4-61*02 F (see comment) 735 81.82 180/220 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 10 7 16 10.7.16 [1.17.38.11] CARERFRSTGGARDFDSW in-frame + Low V-REGION identity (81,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtgaccccatcagcagtggtgatcacttctggagctggatccggcagcccgccgggaagggactggagtggattggacatgttcactatggtggggtcaccaattacaatccttccctccagggtcgggtcatggtgtctatggacacgtccaagagccagttcttcctgacgatgacctccgtgaccgccgcagacacggccacatattactgtgcgagagagcgtttcaggtcgacgggcggagcgagagattttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +4035 JY8QFUQ01A1FEA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CGKQLGPIKG#DYW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcacctttagtagttctggcatgtattgggcccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatgccacaaattacgcagactccgtgaagggccggttcaccatctccagagacaactccatgaacacactgtatctgcaaatgaacagcctgggaaccgatgacacggccttatattactgtggaaagcaattggggcccataaaggggctgactactggggccaggggaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +4036 JY8QFUQ01AVG7B unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 794 84.62 187/221 nt 83.71 185/221 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 10 7 X 10.7.X [1.17.38.11] CARHRSFWSDNC##YFESW out-of-frame + stop codons Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tttccggtgactccatcaccagtactaattattactgGgggctgggtccgccagTcccccagggaagggtctggagtggattggaagtgtctattatcgggggacccagtacctcaacccgtctctccacaatcgagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtctttttggagtgataattgttaactactttgagtcctggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +4037 JY8QFUQ01AGRO9 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 55 100.0 11/11 nt 2 X X 2.X.X [1.X.X.X] null + No rearrangement found ctctggattca +4038 JY8QFUQ01CLT7T No results +4039 JY8QFUQ01DS2A4 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 428 77.24 112/145 nt 8 8 X 8.8.X [1.17.14.X] null + No rearrangement found Low V-REGION identity (77,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctacgtggtcgtcgcatgcctggtccagggcttcttcccc +4040 JY8QFUQ01BBL67 No results +4041 JY8QFUQ01CQ084 No results +4042 JY8QFUQ01BG6U2 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactca +4043 JY8QFUQ01AQYW8 unknown (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 924 91.36 201/220 nt 90.91 200/220 nt 10 7 X 10.7.X [1.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagccccagggaagggactggagtggattggtcatttctatcacattgggagcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagagcatccccgaccagccccaaggctcttcccgctgagcctctgcagcacccagccacgatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +4044 JY8QFUQ01CUEVN productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4045 JY8QFUQ01DCCBW unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4046 JY8QFUQ01BJV9I productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVKDISRSGCFEYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtaCtaaaaagctacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag +4047 JY8QFUQ01A5J2Z No results +4048 JY8QFUQ01DT092 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4049 JY8QFUQ01ATQQA No results +4050 JY8QFUQ01A50E7 No results +4051 JY8QFUQ01CH3O2 No results +4052 JY8QFUQ01CY3N7 unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 964 93.61 205/219 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 8 8 X 8.8.X [2.17.38.11] CAREGEIR*RRRG#WFDPW out-of-frame - stop codons gcgtctggattcaccttcagtgactctggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcacttatatggtatgatggatattataaacaacatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattactgtgcgagagaaggtgaaatacggtgacgacgacggggggtggttcgacccctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4053 JY8QFUQ01CREG4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4054 JY8QFUQ01AJSWL No results +4055 JY8QFUQ01DMRZW productive (see comment) Homsap IGHV4-39*03 F 902 90.0 198/220 nt 89.55 197/220 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-14*01 ORF 2 10 7 12 10.7.12 [2.16.38.11] CTREGPYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) tgctctggtgactccatcagtaatactgattactactgggtctggatccgccagaccccagggaagggactggagtggattgggagatcgatttcagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccatagacacgtccgagaaccggttctccctgaggttgacctctatgaccgccgcagacacggccgtctattactgtacgagagagggaccctactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4056 JY8QFUQ01BM7RX No results +4057 JY8QFUQ01AG74C productive Homsap IGHV1-8*01 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 12 8.8.12 [0.17.38.11] CARGRGYGSYADHW in-frame + tggatacagcttcagcaattatgatatcaactgggtgcggcaggccactggacaagggcttcagtggatggggtggatgaacccccacagtgccaatatcgtctacgcgcagaaatttcagggcagagtcaccatgaccagtgacgcctccataaccacagcctacatggaactgagcaacctgaaatctgacgacacggccgtgtattattgtgcgaggggccgagggtacggaagttacgctgaccactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4058 JY8QFUQ01DHMPB No results +4059 JY8QFUQ01DEL0X unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSEFLLDG#YW out-of-frame - ctctggattcagctttagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaaatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtttttgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgattagtagtgagtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4060 JY8QFUQ01DNF0K productive Homsap IGHV3-7*01 F 882 89.4 194/217 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4061 JY8QFUQ01B6ARD No results +4062 JY8QFUQ01CRH4Y No results +4063 JY8QFUQ01CU6OD No results +4064 JY8QFUQ01CDU8X No results +4065 JY8QFUQ01C7NRF productive (see comment) Homsap IGHV3-23*05 F 826 87.79 187/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa +4066 JY8QFUQ01CKFJO No results +4067 JY8QFUQ01DP9WU No results +4068 JY8QFUQ01BL0WJ No results +4069 JY8QFUQ01DTMAK unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 401 89.0 89/100 nt 8 7 X 8.7.X [1.17.X.X] null - No rearrangement found ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagggtgttgaca +4070 JY8QFUQ01DD7YS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4071 JY8QFUQ01DLWK8 productive (see comment) Homsap IGHV1-8*01 F 835 87.79 187/213 nt 87.32 186/213 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.37.11] CARVGGTHYHYGVDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 96 of V-REGION: 1 nucleotides (from position 189 in the user submitted sequence), (cause frameshift) cggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagattgacgacacggccgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4072 JY8QFUQ01AZDAE unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 440 76.82 116/151 nt 8 7 X 8.7.X [2.17.16.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AZDAE ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (76,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactacttccccgaaccggtgacggtgtcgtggaactcag +4073 JY8QFUQ01BCLHY productive (see comment) Homsap IGHV1-24*01 F 957 94.39 202/214 nt 93.93 201/214 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD3-16*01 F 2 8 8 11 8.8.11 [0.17.38.11] CVGDVGWGYPQGW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); cggatacaccctcaatgaattatccatgcactgggtgcgacagactcctggaaaagggcttgagtcgatgggcggAttttgatcctgaatatggtaaaacaatctacgcgcagaagttccagggcagagtcaccatgaccgaggacacatctgcagacacagcctacatggagttgagaagcctgagatttgaggacacggccgtgtattattgtgtcggagatgtcggctggggatacccccaaggctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4074 JY8QFUQ01BDD2F No results +4075 JY8QFUQ01CDTDW No results +4076 JY8QFUQ01A1E4A No results +4077 JY8QFUQ01DHS0J productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) ctctggattcacctttagaagctatgccatgagctggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4078 JY8QFUQ01ANPYU unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPLGVG#FDNW out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4079 JY8QFUQ01BRMTT productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 800 86.05 185/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] FARDSSNWSDAFDIW in-frame - Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactttgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4080 JY8QFUQ01DRNVI productive Homsap IGHV3-21*04 F 963 94.01 204/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 163 76.79 43/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSHQVDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcgacttcagtagatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttgatagtaattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcgctgtttctgcaaatgaacagcctgagagccgatgacacggccgtgtattactgtgcgagagccgtgtcgcatcaggtggacgtctggggccaaggggccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4081 JY8QFUQ01BB4R2 unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPLGVG#FDNW out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaaccaagatgGgaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4082 JY8QFUQ01B95P9 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4083 JY8QFUQ01BKUF9 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 933 91.82 202/220 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKAGRGLIRPNNWFDPW in-frame - agcctctggatttaccttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcggggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4084 JY8QFUQ01AECJJ No results +4085 JY8QFUQ01A6UXG No results +4086 JY8QFUQ01C39VS unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 789 84.55 186/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD2-21*01 F 1 8 8 X 8.8.X [2.17.38.11] CARRSGRDG#WFDSW out-of-frame - Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) aatctctggattcatctttgccgactatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtcgcagatattaatggaagaggtgctgccgcacactacgcagactccgtgacgggccgcttcaccctctacaaagacggttccaagaatacgatgtatctgcaaatgaggaccctgagagacgacgacacggccaaatattactgtgcgagacgaagtgggcgtgatggggctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4087 JY8QFUQ01AM7GA No results +4088 JY8QFUQ01BH8UX unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 998 96.28 207/215 nt 95.35 205/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.16.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaagggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataatttacggtgactactgggggcccaggggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4089 JY8QFUQ01DE15S No results +4090 JY8QFUQ01BT9VW productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARVRGYYGGQYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +4091 JY8QFUQ01B44L7 No results +4092 JY8QFUQ01AYT06 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 245 58.55 113/193 nt 8 8 X 8.8.X [1.17.30.X] null - No rearrangement found Low V-REGION identity (58,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4093 JY8QFUQ01AYQNM unknown (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacatttagtaactactggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4094 JY8QFUQ01C0ALR productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 868 89.35 193/216 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [2.17.38.11] CASGGYSGSGEYFLRW in-frame - gcctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4095 JY8QFUQ01ACUIR No results +4096 JY8QFUQ01DWE3X productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame - gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +4097 JY8QFUQ01A5EAU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARDLYGTDDLW in-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtaccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +4098 JY8QFUQ01DFR67 No results +4099 JY8QFUQ01DGFY7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame - ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4100 JY8QFUQ01C8KXH No results +4101 JY8QFUQ01A2VEW unknown (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F 121 50.97 105/206 nt 8 8 X 8.8.X [1.17.34.X] null + No rearrangement found ctctggattcaactttgaagattatgccatgtactgggtccgacaacctccagggaagggcctggagtgggtctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4102 JY8QFUQ01BOMRH No results +4103 JY8QFUQ01BSU32 No results +4104 JY8QFUQ01AX4Q2 unproductive Homsap IGHV3-7*01 F 1022 96.79 211/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CARYDFLEWLFLRG#YYFDYW out-of-frame + cctctggattcacctttagtgactattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcagatgaacagcctgagagtcgaggacacggctatgtattactgtgcgaggtacgattttttggagtggttattcctccggggcactactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccc +4105 JY8QFUQ01BUW2X unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 134 68.85 42/61 nt 8 X X 8.X.X [1.10.X.X] null + No rearrangement found cctctggattcacctttagtaaccattggatgaactgggtccagggcttcttcccccagga +4106 JY8QFUQ01CU30H productive (see comment) Homsap IGHV3-9*01 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [1.17.37.11] CAKATTAWYSGGLDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 123 in the user submitted sequence), (cause frameshift) ctctggattcaactttgatgattacggcatgcactgggtccggcaacgcccagggatgggcctggagtgggtcgcaggtattagttataataatggccacaaagaatatgcggactctgtgagggccgattcaccatctctagagacaacgccaggaagtccctgtatctgcagatggacagtctgagagttgaggacacggccttgtattattgtgcaaaggctacaactgcctggtattcaggcggtctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4107 JY8QFUQ01BRYZC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4108 JY8QFUQ01CYMFP No results +4109 JY8QFUQ01A5V13 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1056 98.61 213/216 nt 97.69 211/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.16.38.11] CARDFFIGGYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) ctctggattcaccGttcagtagctatagcatgaactgggtccgccagntccagggaacgggctggantgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4110 JY8QFUQ01CDGEE No results +4111 JY8QFUQ01CVP6Z No results +4112 JY8QFUQ01BRVEF No results +4113 JY8QFUQ01C1EOS unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 998 96.28 207/215 nt 95.81 206/215 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDNYGDY## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4114 JY8QFUQ01CUZCV No results +4115 JY8QFUQ01C70SB productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +4116 JY8QFUQ01BTJ0N productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +4117 JY8QFUQ01C88JT productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4118 JY8QFUQ01C26RF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 720 81.11 176/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 2 8 8 16 8.8.16 [1.17.38.11] CAKGGHDLGSYYYGLDVW in-frame + Low V-REGION identity (81,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaattctccatgtattggatccgccaggctccaggggaggggctggagtggatctcaggtatgaggggacaagattcggccacacactatgcagactccgtgaagggccagttcaccatctcgagagacaacgccaagaacacactgtatctgcagatgaacagtctcagacccgatgacacggccatttattattgcgcgaaaggaggtcatgaccttggcagttactactacggtctggacgtttggggccaagggactacggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4119 JY8QFUQ01CS08M unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 858 89.25 191/214 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CASGGYSGSGEYFLR## out-of-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctgggggccagggcaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4120 JY8QFUQ01DGRQC No results +4121 JY8QFUQ01C1R8S No results +4122 JY8QFUQ01AQTR0 unproductive (see comment) Homsap IGHV3-9*01 F 792 85.25 185/217 nt 84.79 184/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CSKRHGRGSGTLVT#FDHW out-of-frame + stop codons in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); ctctggattcGacctttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtagtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4123 JY8QFUQ01CWANU unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGAGAEGKGGMDV## out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcaccttcaaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggcccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4124 JY8QFUQ01DHKDQ No results +4125 JY8QFUQ01CRD7R productive Homsap IGHV3-9*01 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-11*01 ORF 2 8 8 21 8.8.21 [1.17.38.11] CAKDLFRWNDYSDSNNYYAMGVW in-frame + ctctggattcagttttgaccattttgccttccactgggtccgactagctccagggaagggcctggagtgggtctcaggcattagttgggatagttctgatgtagtctatgcggactctgtgaggggccgcttcatcatctccagagacaacgtcaagaagtccctgtatctggacatgaacagtctgagagttgaggacacggccttgtactactgtgcaaaagatctttttaggtggaacgactatagtgactcgaataactactatgcaatgggcgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +4126 JY8QFUQ01DT8AO productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 813 86.92 186/214 nt Homsap IGHJ1*01 F (see comment) 188 84.62 44/52 nt Homsap IGHD1-26*01 F 1 8 7 13 8.7.13 [1.17.38.11] CVGVGVGSSVSFQYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcactgtcaataacaactacatgggttgggtccgccaggctccagggaaggggctggagtgggtctcgactatttattacggtggcaccacatattacgcagactccgcgaagggccgattcaccatctccagagacacctccaggaacacactttttcttcagatgaacagcctgagaagcgacgacacggctctatattattgtgtgggagtcggagtgggatcttcagtctccttccaatactggggccagggcacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4127 JY8QFUQ01APAFI productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatCccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4128 JY8QFUQ01CDAWJ productive Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame + Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +4129 JY8QFUQ01CQ9EF unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 845 87.91 189/215 nt 87.44 188/215 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4130 JY8QFUQ01AO78J unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 489 82.98 117/141 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (82,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag +4131 JY8QFUQ01ANQ9X No results +4132 JY8QFUQ01C4DFU No results +4133 JY8QFUQ01CT3S3 No results +4134 JY8QFUQ01AHPZ4 unproductive (see comment) Homsap IGHV3-11*06 F, or Homsap IGHV3-48*04 F 781 85.45 182/213 nt 83.57 178/213 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 7 X 8.7.X [1.17.38.11] CAKR*#YGDYW out-of-frame - stop codons in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 86 of V-REGION: 'A' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 82 in the user submitted sequence), (do not cause frameshift) tctggattcaccttcgggaaCctatgccatgacgtgggtccgcctgactcctgggaAaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaacgccaagaacAcctctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcgaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +4135 JY8QFUQ01BSRK2 No results +4136 JY8QFUQ01BBQG8 productive Homsap IGHV4-4*07 F 953 93.95 202/215 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt 8 7 9 8.7.9 [1.17.38.11] CARGDWYFDLW in-frame + tctctggtggctccatcattaatcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtagtcataccagtggaagcaccaggtacaacccctccctcaagagtcgagtcaccgtgtcagcagacacgtccaagaaccagttctccctgaagcttagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggagactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4137 JY8QFUQ01AH6V1 No results +4138 JY8QFUQ01BYX7U No results +4139 JY8QFUQ01DDMNP productive Homsap IGHV3-7*01 F 857 89.15 189/212 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 7 8 10 7.8.10 [X.17.38.11] CVVSSGWLFHYW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4140 JY8QFUQ01A528Y productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 918 91.71 199/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKAGRGLIRPNNWFDPW in-frame - ctctggatttaccttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcggggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4141 JY8QFUQ01CZGPL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame + Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4142 JY8QFUQ01C3CBO productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 835 88.26 188/213 nt 87.79 187/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 3 7 8 10 7.8.10 [0.17.38.11] CASFRVLESGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) tggattcacattcggagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4143 JY8QFUQ01CXP6H unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4144 JY8QFUQ01BBTVQ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 865 88.58 194/219 nt 87.67 192/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) ggcctcctggattcacCctttggttattatggcatgactggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4145 JY8QFUQ01DTK6X No results +4146 JY8QFUQ01AZ8WQ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 807 85.45 188/220 nt 85.0 187/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); ctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggaAgcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactgggaccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactc +4147 JY8QFUQ01DH217 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1036 97.26 213/219 nt 96.8 212/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.16.38.11] CARLDYTRYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggtggctccatcagcagtagtagttactactggggctggatccgccagccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4148 JY8QFUQ01B5YSY unknown (see comment) Homsap IGHV4-59*02 F 894 90.65 194/214 nt 89.72 192/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in CDR1-IMGT at codon 36 of V-REGION: 'GAT' (3 nucleotides at position 20 to 22 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'TACGATCCCTCC' (12 nucleotides at position 107 to 118 in the user submitted sequence), (do not cause frameshift); ctctggtggctccgtcagaGATttttattactggagttgggtccggcagcccccagggaagggactggagtggcttggatatctctattacagagggagcaccaagTACGATCCCTCCtataatccctccctcgagagtcgagtcaccatttcagttgacccgtccaagaaccagttctccctgaagctaaactctgtgaccgctgcggacacggccgtgtattactgcgcgagagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4149 JY8QFUQ01A216B unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 405 77.78 105/135 nt 76.3 103/135 nt 7 6 X 7.6.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (77,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 97 in the user submitted sequence), (cause frameshift) cctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4150 JY8QFUQ01AJAE8 No results +4151 JY8QFUQ01BULC2 No results +4152 JY8QFUQ01AXRKK No results +4153 JY8QFUQ01DOYU9 No results +4154 JY8QFUQ01BRAIG No results +4155 JY8QFUQ01AJJ06 productive Homsap IGHV3-11*01 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 2 8 8 18 8.8.18 [1.17.38.11] CAGSFCGGGCLWPTYHFENW in-frame + ctctggattcccctttaaggactactccatgaactggatccgccaggctccagggaagggactggagtggatttcatacatgagcagcactggtgagaccatatattacgcggactttgtgaagggccgattcaccatctccagggacaccgccaagaatctgttgtttctgcaaatgaattacctgcgagacgaggacacggccatgtattactgtgcgggatcattttgtggtggtggctgcttgtggcccacatatcactttgaaaactggggccagggagccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4156 JY8QFUQ01AOR7N productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctcag +4157 JY8QFUQ01C8YU1 No results +4158 JY8QFUQ01DXHVC unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 459 68.2 148/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (68,20% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctcctcagcctccaccaagggcccatcggtcttcccctgcgcctcgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4159 JY8QFUQ01BL8LS unproductive Homsap IGHV3-21*03 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD1-7*01 F 1 8 8 X 8.8.X [1.17.38.11] CATGAGNWNYIFNF## out-of-frame + cctccggcttcgacttcagtagatacaacataaactgggtccgccaggctccagggcagggactggagtgggtctcctctattagttatagtagcacttacatatactacgcagactcggtgaaaggccgcttcaccatctccagggacaacgccaagaactcggcatctctgcaaatgaacaacctgagagccgaggacacagctgtgtattactgtgcgacaggggccggaaactggaactacatttttaacttctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4160 JY8QFUQ01CHCVV No results +4161 JY8QFUQ01CBF1Z No results +4162 JY8QFUQ01CTSJZ productive Homsap IGHV4-34*03 F 917 92.06 197/214 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 8 7 18 8.7.18 [1.17.38.11] CARSAYCGADCYSADYLQHW in-frame - tgtatggtgggtccttcagtgataactcctggacctggatccgccagcccccagggaaggggctggagtggattggagagatcaatcatagtggaaacaccaactacaacccgtccctcaggagtcgagtaatcatgtcaatagacacgtccatgaaccaattctccctgaagctgacttctgtgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4163 JY8QFUQ01CKW45 productive Homsap IGHV3-9*02 F 891 90.32 196/217 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + ctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4164 JY8QFUQ01DW86D productive Homsap IGHV3-74*03 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKVDSDGWHGTIDRW in-frame + ctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggatagcgatggctggcacggaacaatagaccgctggggccagggagtcctggtcaccgtctccgcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +4165 JY8QFUQ01ASR1L No results +4166 JY8QFUQ01AI26Z No results +4167 JY8QFUQ01BGUEI unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 60 100.0 12/12 nt 2 X X 2.X.X [1.X.X.X] null + No rearrangement found cctctggattca +4168 JY8QFUQ01CXFTI No results +4169 JY8QFUQ01COANG No results +4170 JY8QFUQ01C6K15 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 375 89.25 83/93 nt 88.17 82/93 nt 8 6 X 8.6.X [1.15.X.X] null + No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 4 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggaggggctggagtgggtctcagccattagtggcagtggtagt +4171 JY8QFUQ01BD39R productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame + ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaatatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca +4172 JY8QFUQ01A6LU1 unproductive Homsap IGHV3-7*01 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSAYFSTGY# out-of-frame + tctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaaaggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4173 JY8QFUQ01C0CV0 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CAKEGPTLLTRPLS#W out-of-frame + tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaacttttggtggtagtggtggttctacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaatacgctatatcttcaaatgagcagcctgagagccgaggacacggccatatacttctgtgcgaaagaaggacctacgcttctaactcgccccctctcaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4174 JY8QFUQ01BAQF9 No results +4175 JY8QFUQ01CZ6D5 No results +4176 JY8QFUQ01C02GH No results +4177 JY8QFUQ01A6V15 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-16*02 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGQFGTVMDYW in-frame + cctctggattcacctttaacgactatggcatgacttgggtccgccaggctccagggatggggctgcagtgggtcgcaaccattagtggaagtggcgacagaacattctacgcagactccgtgaagggccgcttcatcgtttccagagacaactccaagaacacgctgtatctgcaaattaccagcccgagagccgaggacacggccgttttttattgtgcgaaaggccagtttggtaccgtcatggactattggggccagggaacccaggtcgtcgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccg +4178 JY8QFUQ01DM4VX productive Homsap IGHV3-7*03 F 865 88.58 194/219 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [2.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame - gcctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +4179 JY8QFUQ01AA4FG No results +4180 JY8QFUQ01ADRD7 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 845 90.29 186/206 nt 89.81 185/206 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 30 of V-REGION: 9 nucleotides (from position 15 in the user submitted sequence), (do not cause frameshift) tctctggtgactcccacttctggagctggatccggcagcccccgggaaagggcctggagtggattggttatgtctataacagtgggaccaccaactacaacccctccctcaggagtcgagtcaccatgtctatagacacgtccaagaagcagatctctctgaggttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactcctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +4181 JY8QFUQ01AIQK6 No results +4182 JY8QFUQ01DDSRJ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4183 JY8QFUQ01BAM3C productive Homsap IGHV3-7*01 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + tctggattccagtttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +4184 JY8QFUQ01C4VFW productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4185 JY8QFUQ01DJ70M unknown (see comment) Homsap IGHV3-23*05 F 102 55.24 58/105 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons cctctggattcgtctttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4186 JY8QFUQ01BZLBZ productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAYFSTGYW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4187 JY8QFUQ01DS8U8 productive Homsap IGHV3-11*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame - cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4188 JY8QFUQ01DJGQ4 productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaAagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4189 JY8QFUQ01BBNNQ No results +4190 JY8QFUQ01CY764 productive Homsap IGHV3-21*04 F 990 95.39 207/217 nt Homsap IGHJ3*01 F 142 76.0 38/50 nt Homsap IGHD4-17*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame + ctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4191 JY8QFUQ01DUPRD productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 95 of V-REGION: 'G' (1 nucleotides at position 193 to 193 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgaGcccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4192 JY8QFUQ01CBXSO unproductive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1043 96.43 216/224 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD4-11*01 ORF 2 8 10 X 8.10.X [1.17.38.11] CTRGGIQL#AYW out-of-frame + cttctggattcacctttggtgattatgctatgagttggttccgccaggctccagggaaggggctggagtgggtaggtttcattggaggcagagctcatggtggggcaacagaatacgccgcgtctgtgaaaggcagattcatcatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattattgtactagagggggaatacagttatgcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +4193 JY8QFUQ01ABKEP No results +4194 JY8QFUQ01AZK7Y productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARAGYCNNGVCYSSYFDFW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccggggaaggggctggtgtgggtctcacgtatgaatagtgatggcagtgacataaggtacgcggactccgtgaggggccgattcaccatctccagagacaacaccaagaacacgctgtatctacaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagcgggatattgtaataatggtgtatgctactccagttactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +4195 JY8QFUQ01AN73J productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacct +4196 JY8QFUQ01DKQIL productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [0.17.38.11] CARGFYGDHFDSW in-frame + tggatacaccttcagcgactactacatacactggctgcgacaggcccctggacaacgacttgagtggatgggatggctgaaccctaataatggtgacacagcttatggccagagctttcagggccgggtcaccatgaccagggacacgtccgtcagcacagtgtacgtggaggtgaggaggctgagatctgacgacacagccctttatttctgtgcgagaggcttttacggtgaccactttgactcctggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +4197 JY8QFUQ01AHM6C No results +4198 JY8QFUQ01C7M32 unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 995 93.39 212/227 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 10 9 X 10.9.X [1.17.38.11] CARGSSRGGILMGSTMN#DYW out-of-frame - tctccggggacagtgtctctaccacccgtgctgcttggaactggatcaggcagtccccatcgggaggccttgagtggctgggaaggacatactacaggtccaagtggcttaatgattatgcagtgtctgtgaaaagtcgaattaccatcaatccagacacatccaagaaccagttttccctgcagttgaaatctgtcattcccgaggacacggctgtttattactgtgcaagaggttccagtcgcgggggaattctgatggggtctactatgaacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +4199 JY8QFUQ01CRMOX productive (see comment) Homsap IGHV3-9*01 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.16.38.11] CAKDGDSGWDYYDHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift) ctctggatttaactttgatcaatatgccatgtattggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaaggacccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4200 JY8QFUQ01DWDCF No results +4201 JY8QFUQ01DPSK7 unknown (see comment) Homsap IGHV3-11*01 F (see comment) 468 68.2 148/217 nt 67.28 146/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (68,20% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'T' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); ctctggattcaccttcaGgtgactactacatgagctggatccgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcaTgggtatacctggcagactccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4202 JY8QFUQ01CXSTH unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F (see comment) 576 73.73 160/217 nt 73.27 159/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (73,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 74 of V-REGION: 'T' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggTccgattcaccatctccagagacaattccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4203 JY8QFUQ01AF6KD unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*03 F or Homsap IGHV4-59*07 F 481 94.44 102/108 nt 93.52 101/108 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD4-17*01 F 1 8 X X 8.X.X [1.16.10.11] CAKTTMTSVTTTGS#PL out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 55 of V-REGION: 106 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) ctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttaaccgctgcggacacggccgtctattactgtgcgaaaacaacaatgacttcggtgactacgactggttcgacccctgggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4204 JY8QFUQ01B5FLY productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CAREKGSGPPTGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggccaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4205 JY8QFUQ01ATAE0 No results +4206 JY8QFUQ01BY0E2 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 949 93.52 202/216 nt 92.59 200/216 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARFSGSYKSAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); tctggatacatctttaccgactattggatcggctgggtgcgccagacggccgggaaAaggcctggagtggatggggaAtcatctatcctggtgactctgacaccagttatggcccgtccttccaaggccaggtcaccatttcagccgaccagtccatcaccaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagattcagtgggagttacaaatcggcttttgatatctggggccgagggacaatggtctccgtctcttcagcatcccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccgagg +4207 JY8QFUQ01BDAQ6 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 949 91.56 206/225 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 7 11 8.7.11 [5.17.38.11] CARFGPLTRPDYW in-frame - gcctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4208 JY8QFUQ01DGVPH No results +4209 JY8QFUQ01AI4VB unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 420 76.19 112/147 nt 8 7 X 8.7.X [1.17.16.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AI4VB ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (76,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactacttccccgaaccggtgacggtgtcgtggaactca +4210 JY8QFUQ01BH58R productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 769 84.26 182/216 nt 82.87 179/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 7 7 9 7.7.9 [2.16.38.11] CTGLTYPDDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 30 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) cgtctgggatttaccttcagtaagttctgatgcattgggtccgccaagctccagggaagggctgacttgggtctcacgtataatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +4211 JY8QFUQ01CHR9J No results +4212 JY8QFUQ01BG0NL unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANYW# out-of-frame + ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4213 JY8QFUQ01A5JH6 No results +4214 JY8QFUQ01CNH36 productive Homsap IGHV3-66*02 F, or Homsap IGHV3-66*03 F 863 89.3 192/215 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-25*01 F 1 8 7 11 8.7.11 [1.17.38.11] CARDGRGGDLDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tgtctgggttctccgtcagtttcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatctatgccgatggaagtacattctatgcagactccgtgaagggccgattcatcatctccagagacaattcaaagaacacgctcaatcttcaaatgaatagtttgagagttgacgacacggctgtgtattactgtgcgagagatgggcgcggcggtgaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4215 JY8QFUQ01CO5QA productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 728 82.33 177/215 nt 81.86 176/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 3 8 7 15 8.7.15 [1.17.38.11] CARDWGGSFDRYYFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); tccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggctgggAgacatcaactttaaaggaagcaccaattacaacccgtccctcaagagtcgactcaccatattagcagacttgtccaggaatcgcttctctctagaactaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtgggagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4216 JY8QFUQ01A78YS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 8 8 8.8.8 [1.17.38.11] CARGVPFYDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION cctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggtcccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4217 JY8QFUQ01CDD8G productive (see comment) Homsap IGHV3-11*01 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4218 JY8QFUQ01B16GZ No results +4219 JY8QFUQ01AH7E6 No results +4220 JY8QFUQ01BIFZI unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 96 95.24 20/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattcaccttaagtga +4221 JY8QFUQ01A0B86 productive Homsap IGHV3-33*02 F, or Homsap IGHV3-33*03 F 148 65.43 53/81 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 X X 14 X.X.14 [X.X.27.11] CATDDSNGWDEVADYW in-frame - gcctctggattcaccttcagctcccattggatgagctggatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4222 JY8QFUQ01BTH6E unproductive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 281 81.4 70/86 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD6-13*01 F 2 X X X X.X.X [X.X.28.11] CVKDRKGSNWYYFEN## out-of-frame + Low V-REGION identity (81,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggcccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +4223 JY8QFUQ01DLXBB unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 509 92.37 109/118 nt 8 8 X 8.8.X [1.17.5.X] null + No rearrangement found ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagaccca +4224 JY8QFUQ01AKMZK productive Homsap IGHV3-7*01 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + tctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggattctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4225 JY8QFUQ01DRQX0 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.37.11] CARGRIVSVGMSGWFDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 86 of V-REGION: 1 nucleotides (from position 163 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4226 JY8QFUQ01AL7AV productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 846 88.02 191/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactctgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +4227 JY8QFUQ01AEQWG No results +4228 JY8QFUQ01DHW5J No results +4229 JY8QFUQ01BLLMD productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt 89.14 197/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 65 to 65 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaAggggctggagtggaTttgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4230 JY8QFUQ01CV6T1 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 926 92.56 199/215 nt 92.09 198/215 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 86 in the user submitted sequence), (cause frameshift) tctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtactaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacggtaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattattgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +4231 JY8QFUQ01DU4I8 No results +4232 JY8QFUQ01AOKIY productive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4233 JY8QFUQ01AQYMH No results +4234 JY8QFUQ01CH5ZD No results +4235 JY8QFUQ01BQYEH productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactanttccccgaaccggtgacggtgtcgtggaactc +4236 JY8QFUQ01CHECP No results +4237 JY8QFUQ01DCPGQ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 918 91.24 198/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKGRGYNDYGLDYW in-frame + ctctggattcaccttcagtgactatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtgacagttattttatatgatggaagtagaaaatactatgcagactccgtgaagggccgattcgccatctccagagacgtttcgaggaacacgttgtatctgcagatgaatagcctgagacctgaggacacggctgtatactactgcgcgaaaggacgtggatataatgactacggcctcgactactggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtctcccctggcacctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +4238 JY8QFUQ01B3N8H productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag +4239 JY8QFUQ01DSHP5 productive (see comment) Homsap IGHV4-59*02 F 899 90.7 195/215 nt 89.77 193/215 nt Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD1-26*01 F 3 8 7 15 8.7.15 [1.17.38.11] CARGGSGGAYWNLIRDW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'GAT' (3 nucleotides at position 21 to 23 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'TACGATCCCTCC' (12 nucleotides at position 108 to 119 in the user submitted sequence), (do not cause frameshift); tctctggtggctccgtcagaGATttttattactggagttgggtccggcagcccccagggaagggactggagtggcttggatatctctattacagagggagcaccaagTACGATCCCTCCtataatccctccctcgagagtcgagtcaccatttcagttgacccgtccaagaaccagttctccctgaagctaaactctgtgaccgctgcggacacggccgtgtattactgcgcgagaggtgggtccggtggggcctactggaatctgatccgggactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4240 JY8QFUQ01A4D36 productive (see comment) Homsap IGHV4-61*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 15 10.7.15 [0.17.37.11] CARNPSYSNSHQHCDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 113 in the user submitted sequence), (cause frameshift) ctggtgcctccatcaacagtggtagttactactggagttgggttcggcagcccgccgggaagggactggagtggattgggcgtatctacaccagtgggagcaccaactacaaccctccctcaagagtcgagtcgccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctatttttgtgcgagaaatccctcttatagcaattcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4241 JY8QFUQ01C7YVI No results +4242 JY8QFUQ01B1TWL No results +4243 JY8QFUQ01AV6UJ No results +4244 JY8QFUQ01ATA76 productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1110 100.0 223/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD4-17*01 F 3 8 10 12 8.10.12 [1.17.38.11] CTKCSVTIYFLTTG in-frame + ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttactttttgactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4245 JY8QFUQ01A68R4 No results +4246 JY8QFUQ01BWBBF No results +4247 JY8QFUQ01DF0UH No results +4248 JY8QFUQ01CPHAF No results +4249 JY8QFUQ01DPUG7 No results +4250 JY8QFUQ01DS4KK unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*03 F or Homsap IGHV4-34*06 F 796 85.19 184/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [2.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. gtctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagtcccaactacagcccgtccctcaatagtcgagtcatcatatcgatagacatgtccaagaaccaggtctccctgaagctcttctctgtgaccgccgcggactcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4251 JY8QFUQ01AE4IA No results +4252 JY8QFUQ01BPN3H productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.17 200/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKIDSRNYDFWSGYYAHW in-frame + ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtttattactgcgcgaaaatagatagtcggaattacgatttttggagtggttattatgcacactggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4253 JY8QFUQ01CL6BN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggtccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4254 JY8QFUQ01AT12H No results +4255 JY8QFUQ01BLAOP productive Homsap IGHV3-30*10 F (see comment) 724 81.94 177/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame + Low V-REGION identity (81,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4256 JY8QFUQ01DOIL0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcttccccgaaccggtgacggtgtcgtggaactca +4257 JY8QFUQ01DUKA9 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGggcacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctncctggtcaaggactcanttccccgaaccggtgacggtcgtgcgtggaactcag +4258 JY8QFUQ01BYE5H productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 770 85.65 179/209 nt 85.17 178/209 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 2 8 6 14 8.6.14 [X.17.38.11] CARERGSGPPTGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 76 in the user submitted sequence), (cause frameshift) gggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttcttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaagaggttcggggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4259 JY8QFUQ01CDHQW productive (see comment) Homsap IGHV3-48*03 F 853 89.2 190/213 nt 87.79 187/213 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 7 8 13 7.8.13 [1.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 27 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 2 nucleotides (from position 45 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagttcttatgcatgaactggtccgcctgtccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +4260 JY8QFUQ01C1GO1 productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4261 JY8QFUQ01CU1LQ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggcGtggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4262 JY8QFUQ01DHUMB productive (see comment) Homsap IGHV1-2*02 F 785 85.85 182/212 nt 85.38 181/212 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.37.11] CARDWGGTYAPLDNW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 99 of V-REGION: 2 nucleotides (from position 197 in the user submitted sequence), (cause frameshift) tggatacattttcaccggctactatatacattgggtgcgacaggccgctggacaagggcttgagtggatgggatacatcgacccttacagaggtgacacaaggtttgcagagaaatttcagggcagggtcaccttgaccagagacacgtccatcagtacagcctacatggaaatgaccggcctgacgtctgaggacggccatcttttactgtgcgagagattggggtggcacgtacgcaccgcttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4263 JY8QFUQ01AY2ED unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 432 77.78 112/144 nt 8 8 X 8.8.X [1.17.13.X] null + No rearrangement found Low V-REGION identity (77,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctacgtggtcgtcgcatgcctggtccagggcttcttccc +4264 JY8QFUQ01CVUGR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 786 85.51 183/214 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [0.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ctctgatacaattagtcgttatggcatgcactgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtccgtggaactcag +4265 JY8QFUQ01ANN07 productive (see comment) Homsap IGHV4-4*07 F 844 88.73 189/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 7 11 8.7.11 [1.17.37.11] CARSGWDNQFDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'TGGCAC' (6 nucleotides at position 22 to 27 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 214 to 214 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 109 in the user submitted sequence), (cause frameshift) ctctggtgtcgccaccagtagTGGCACttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaaccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtatTtactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctcaggagcacctccgagancacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4266 JY8QFUQ01A7QYN No results +4267 JY8QFUQ01BA9KM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccGagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4268 JY8QFUQ01DNJKW No results +4269 JY8QFUQ01A7C84 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 940 93.06 201/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'CAG' (3 nucleotides at position 73 to 75 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'T' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggctgggatgggtcCAGtctggtTattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4270 JY8QFUQ01DUX6F productive Homsap IGHV3-11*01 F (see comment) 783 84.79 184/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVRDGARRTNQWLAHDFW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagctttaatgccttctatatgggttgggtccgccaggctccaggaaaggggctggagtggatttcgtacattaactctggtggtagtgacacatattacgcagactctgtgaagggccgattcaccatctccagggacaacgcctgggacacaatgtacttggaaatgaacagcctgagagccgaagacacggccgtctactattgtgtgagagatggcgctagaaggacgaatcagtggctggcccatgacttctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcancgctgcctggtcagggcttcttccc +4271 JY8QFUQ01DJILO productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 814 86.57 187/216 nt 85.65 185/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 7 8 9 7.8.9 [1.16.38.11] CTGLTYPDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 28 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) cgtctggatttaccttcagtaagttctgatgcattgggtccgccaagctccagggaagggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4272 JY8QFUQ01C3R6B productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CARAYSGPGPYYFDYW in-frame + cctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +4273 JY8QFUQ01AZ2OV productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 860 88.53 193/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CTRVGTFNWFGPW in-frame + cctctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4274 JY8QFUQ01AE3KX No results +4275 JY8QFUQ01CHVDW productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 678 79.91 171/214 nt 79.44 170/214 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) ctctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +4276 JY8QFUQ01DTEQ6 No results +4277 JY8QFUQ01BNJV1 No results +4278 JY8QFUQ01CJLZD No results +4279 JY8QFUQ01DXF7R productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame - gttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4280 JY8QFUQ01DAGZ3 No results +4281 JY8QFUQ01AG95A No results +4282 JY8QFUQ01BECR8 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 769 83.8 181/216 nt Homsap IGHJ2*01 F (see comment) 32 63.16 12/19 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttcccgaaccggtgacggtgtcgtggaactcag +4283 JY8QFUQ01CT0C1 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 13 8.8.13 [1.17.38.11] CARGGGGKSIPLDNW in-frame + gtctggcttcacgttcagtagttatggcatgcaatgggtccgccaggctccaggcaaggggctggagtgggtggcagttatttggtatgatggaagtaataaatattatgcagactccgtgaagggccgattcgacatctccagagacaattccaagaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatgtaccattgtgcgagaggcggcggtggtaagtccattccacttgacaactggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4284 JY8QFUQ01DUQPM productive (see comment) Homsap IGHV4-61*02 F 986 94.95 207/218 nt 93.58 204/218 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-10*01 F 2 9 7 13 9.7.13 [1.17.38.11] CARGSGTYYNPMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'ACTG' (4 nucleotides at position 34 to 37 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 3 nucleotides (from position 30 in the user submitted sequence), (do not cause frameshift) tttctggtgcctccatcagcagtggtagttactACTGgggactggatccggcagcccgccgggaagggactggagtggattgggcgtatccataccagtgggggAcaccaactacaccccctccctcaagagtcgactcaccatatcagtagacgcgtccaagaaccaggtctccctgaggctgagctctgtgaccgccgcagacacggccgtgtattactgtgcgagaggttcggggacttattacaaccctatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +4285 JY8QFUQ01BY39E productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 94.17 210/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaaGtatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4286 JY8QFUQ01BHPUL No results +4287 JY8QFUQ01DJ6ES productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*03 F or Homsap IGHV4-59*07 F 486 94.5 103/109 nt 92.66 101/109 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 X 15 8.X.15 [1.16.10.11] CAKNNNDFGDYDWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 106 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) tctctggtgtctccatcagtagttcctactggagttggatccggcagTcccccagggaagggcctggagtggattggttaaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4288 JY8QFUQ01B7RGK No results +4289 JY8QFUQ01CZK7C productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 143 75.0 39/52 nt Homsap IGHD6-19*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAGAEAGLLTYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcgggggcagaggctggcttattgacgtactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +4290 JY8QFUQ01DSLQR unproductive (see comment) Homsap IGHV3-43*01 F 999 95.85 208/217 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAK**DWVLVLL*PL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctcaggattcacatttgctgaatataccatgcactgggtccgtcaagttccggggaagggtccggagtgggtctctcttattagttgggatggtggcagcacatactatgcagactctgtgaagggccgattcaccatctccagagacaacagcaaggactccctgtatctgcaaatgaacagtctgagaactgaggacaccgccttgtattactgtgcaaaatgataggattgggtccttgtactactttgaccactggggccaggggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcc +4291 JY8QFUQ01A9QSI No results +4292 JY8QFUQ01C85OD No results +4293 JY8QFUQ01BGZM8 No results +4294 JY8QFUQ01BYFP6 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 88 51.91 68/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +4295 JY8QFUQ01BHC1U productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD5-12*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARDGSAHSSIYHYYYGMDVW in-frame - ctctggattcaccttcagttctcacactatgaactgggtccggcaggctccagggaaggggccggagtgggtctcaaccattggtactagaggtagatccatatactacgcggactcagtgaagggccgattcaccacctccagagacaacgccaagaaatcactttatctggatatgcacagcctgagagccgaggacacggctatctattactgtgcgagagatggcagtgcacactcgtcgatctatcattactattacggcatggacgtctggggccaagggaccacggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4296 JY8QFUQ01A4PHC unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CANEVGYCSSGG# out-of-frame + ctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccagggaaggggctggagtgggtctcaactattcgtgcccgtggtgataggacacactacgcggactccgtgaagggccgcttcaccatctctagagacaattcaaaggacaccctgtatttgcaaatgtacagcctgcgagtcgaggacacggccgtctattactgtgcgaacgaagtcgggtactgtagtagtggggggggaccaggggacccctggtcaccgtctcctcagcatcccctgaccagccccaaggctcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4297 JY8QFUQ01CR7MJ No results +4298 JY8QFUQ01BDCL8 No results +4299 JY8QFUQ01C33A4 productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 678 79.91 171/214 nt 79.44 170/214 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) ctctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +4300 JY8QFUQ01DKOPH No results +4301 JY8QFUQ01BCKHU No results +4302 JY8QFUQ01CVL8I No results +4303 JY8QFUQ01CM840 No results +4304 JY8QFUQ01BXQ3T No results +4305 JY8QFUQ01DUUTN productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 803 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggttcctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca +4306 JY8QFUQ01CLSTN productive (see comment) Homsap IGHV1-69*02 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD2-8*01 F 2 8 8 20 8.8.20 [0.17.38.11] CARGYCTNGVCYRGSYNWLDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggaggcccctccggcagttataccatcaactgggtgcgacaggCcccctggacaagaccttgagtggatgggaaggatcatccctacccttggcatagtaaactacgcacagaagttccagagcagagtaacgattaccgcggacaagtggacgagcacaatcttcatggagctgagcaacctgagacctgaggacacggccgtgtattattgtgcgagaggatattgtactaatggtgtgtgttatcgcggctcgtacaactggctcgacccctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4307 JY8QFUQ01AFV38 No results +4308 JY8QFUQ01A6HOT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-6*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRSYSRTSEFDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaatgtcaagaacacggtttatctgcagatgagcagcctgagagtcgaggacacgggcgtatattattgtgtgaggtcgtatagtaggacatctgagtttgactactggggcccgggaacccaagtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4309 JY8QFUQ01AT40O No results +4310 JY8QFUQ01AZ2OO No results +4311 JY8QFUQ01DWGDY unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRRGMVAGRYD##FDIW out-of-frame - stop codons in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttatagcatgaacCtgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgccttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4312 JY8QFUQ01ASYKF No results +4313 JY8QFUQ01CWHMR No results +4314 JY8QFUQ01AS3UT unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagnacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4315 JY8QFUQ01BN6SA unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*03 F (see comment) 123 72.92 35/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDTLEVVSNMDDAFDL# out-of-frame + Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtgggccaagggacagtggtcaatgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4316 JY8QFUQ01DLJ3Q productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1069 98.2 218/222 nt 97.75 217/222 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD5-18*01 F 3 8 10 19 8.10.19 [1.17.37.11] CTTDYGGYSYGFAGMRAFDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 161 in the user submitted sequence), (cause frameshift) ctctggattcactttcaataacgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgttttaaaagcaaaactgatggtggggcaacagactacgcttcacccgtgaaaggcagattcaccatctcaagagatgattcaaaaacacgctgtatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtaccactgactacggtggatacagctatggttttgcggggatgcgcgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4317 JY8QFUQ01BJ0Q1 No results +4318 JY8QFUQ01BW1R0 No results +4319 JY8QFUQ01CTGCU No results +4320 JY8QFUQ01C3JQ3 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame + ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +4321 JY8QFUQ01BYP7W No results +4322 JY8QFUQ01ATVY4 unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F or Homsap IGHV7-81*01 ORF 139 58.88 63/107 nt 8 8 X 8.8.X [0.17.2.X] null - No rearrangement found cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4323 JY8QFUQ01AYZBR productive (see comment) Homsap IGHV3-9*01 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*02 F 1 8 8 16 8.8.16 [1.17.38.11] CVKDMQGVGDIAIGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); tctggattcagccttgatgattatgccatgaactgggtccggcaagctccagggaaTgggcctggagtgggtctcatttatcagttggaatagtggtattatagcctatgcggactctgttaagggccgcttcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagcctgagacctgaagacacggctttgtattactgtgtaaaagatatgcaaggagtcggggacatagcgattggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4324 JY8QFUQ01AVUES No results +4325 JY8QFUQ01APS2Q unknown (see comment) Homsap IGHV4-61*02 F 888 89.55 197/220 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4326 JY8QFUQ01AL95Z productive Homsap IGHV3-7*01 F 928 91.78 201/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [2.17.38.11] CVSSPYFYDSNGYW in-frame - gcctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4327 JY8QFUQ01CXG7S No results +4328 JY8QFUQ01BYGTR No results +4329 JY8QFUQ01BV3K1 productive Homsap IGHV1-18*01 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt 8 8 8 8.8.8 [0.17.38.11] CARGDYFDHW in-frame + tggttacacctttaccagctatggtctcagctgggtgcgacaggcccctggccaagggcttgagtggatgggatggatcttcgtttttaacggtaacacaaaatatgcacagcacctccagggcagagtcaccatgaccacagacacatccacggacacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagaggtgactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4330 JY8QFUQ01A6013 No results +4331 JY8QFUQ01ABGJ8 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4332 JY8QFUQ01AI6N9 productive (see comment) Homsap IGHV3-48*01 F (see comment) 753 84.36 178/211 nt 83.41 176/211 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [0.17.38.11] CSRDGRRGYDLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,36% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 80 in the user submitted sequence), (do not cause frameshift) tggattcaccttcggaacctatggcCatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4333 JY8QFUQ01BXJV2 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 643 77.31 167/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (77,31% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactatttccccgaaccggtgacggtgtcgtggaactcag +4334 JY8QFUQ01AHKVZ No results +4335 JY8QFUQ01DRF8N No results +4336 JY8QFUQ01AZZUP productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 919 91.32 200/219 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKAGRGLIRPNNWFDPW in-frame - gcctctggatttaccttcagtggctatggcgtgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcggggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4337 JY8QFUQ01BK5AV unproductive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ6*01 F (see comment) 94 61.29 38/62 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSGYYSTGY# out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ1*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +4338 JY8QFUQ01AZ72P productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 21 8.8.21 [0.16.38.11] CARGWLTAADTGVASGHDWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tggatacaccttcaccagctactatatgcactggatacgacaggcccctggacaaggcttgagtggatgggaataatcaaccctagtggtggtaccacaaggtacgcacagaagttccagggcagagtcttcatgaccagagacacgtccacgagcacagtccacatggaggtgaacggcgtaagatctgacgacacggccgtgtattactgtgcccgagggtggctgacagcagctgataccggggtggcgtcagggcacgattggttcgactcctggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4339 JY8QFUQ01DF7F3 No results +4340 JY8QFUQ01DQQU9 No results +4341 JY8QFUQ01CDRDN No results +4342 JY8QFUQ01A04MA No results +4343 JY8QFUQ01AJY9D No results +4344 JY8QFUQ01AF4NQ No results +4345 JY8QFUQ01AI1BW No results +4346 JY8QFUQ01B0MWW unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found tgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +4347 JY8QFUQ01CN403 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 939 93.46 200/214 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-2*01 F 2 8 7 10 8.7.10 [1.17.38.11] CARDASGWFDRW in-frame + ctctggtggctccatcagcggtttctactggaactggatccggcagcccccagggaagggactggagtggattgggtttatccattccagtgggagcaccgactacaatgcctccctcaagagtcgagtcaccatgtcagtagacacgtccaagcaccagttctccctgaggctgagctctgtaaccgctgcggacacggccgtgtattactgtgcgagagatgcctcaggctggttcgaccgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccctcaagatgggaacgtggtcgtcgcatgcctggtccaggcttcttccccca +4348 JY8QFUQ01DBG2T unknown (see comment) Homsap IGHV3-7*01 F 1026 96.77 210/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttcccccgag +4349 JY8QFUQ01CZ44B No results +4350 JY8QFUQ01B54RP No results +4351 JY8QFUQ01BD8JG No results +4352 JY8QFUQ01BYVUD productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 948 93.93 201/214 nt 92.99 199/214 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD2-8*01 F 3 7 8 10 7.8.10 [1.16.38.11] CAREVSDAFEMW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 23 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 31 in the user submitted sequence), (cause frameshift) tctggattcatctttgatgatttggcatgaattggtccgccaagctccagggaaggggctggagtgggtcgctggtatcagttggaatggtggcaaagcaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4353 JY8QFUQ01CIDTD productive Homsap IGHV3-66*02 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame + ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccccttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4354 JY8QFUQ01ADNPS productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDPRSVSRYSLFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtgactattggatgagctgggtccgccaggctccagggaaggggctagagtgggtggccaacataaatagagatggaagtgagcaacactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacatggctatgtatttttgtgcgagagatcctcgttccgtgagcaggtactctttatttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4355 JY8QFUQ01BA89B No results +4356 JY8QFUQ01CHBDO productive Homsap IGHV4-34*10 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame + tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4357 JY8QFUQ01AHW9S productive Homsap IGHV3-11*01 F 913 91.67 198/216 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARADCDDACYIINSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaacttactgtatctgcaaatgaacggtctgagaactgacgacacggccttctattattgtgcgagagccgattgtgacgatgcctgctacataattaactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctccgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4358 JY8QFUQ01BFAXK productive (see comment) Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 393 91.49 86/94 nt 90.43 85/94 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD5-18*01 F 3 X X 15 X.X.15 [X.X.31.11] CARSDEEYSYGDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'ACTAT' (5 nucleotides at position 21 to 25 in the user submitted sequence), (cause frameshift); gtctggattcaccttcagtaACTATgagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatcggacgaggaatacagctatggggatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccctggcaccctcctcaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4359 JY8QFUQ01DA04L productive (see comment) Homsap IGHV3-23*05 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [2.17.38.11] CAKRPPGTIDRW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) agcctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4360 JY8QFUQ01A4SRM No results +4361 JY8QFUQ01BQPRR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4362 JY8QFUQ01CUTLJ productive Homsap IGHV3-7*01 F 975 95.33 204/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [0.17.38.11] CAKGGGNGDLDYW in-frame - tggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4363 JY8QFUQ01B28XE unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 85 62.26 33/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + stop codons ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcaagattcggcccacttactcgacctgactactggggcccagggtaactttggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4364 JY8QFUQ01CJDFB productive (see comment) Homsap IGHV3-7*01 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'T' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); ctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaTggggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4365 JY8QFUQ01B9W5S No results +4366 JY8QFUQ01DFK28 No results +4367 JY8QFUQ01C5NXR No results +4368 JY8QFUQ01CK1GE No results +4369 JY8QFUQ01DTPH2 No results +4370 JY8QFUQ01BJ1UU productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CAREKGSGPPTGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggccaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +4371 JY8QFUQ01C2CQM No results +4372 JY8QFUQ01DBCQJ productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4373 JY8QFUQ01CCLE2 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 828 87.1 189/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARLRSFGDYPLDVW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4374 JY8QFUQ01DD6ZQ productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctaaatttgacttcagtgactatggcatgaactgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +4375 JY8QFUQ01BET5U No results +4376 JY8QFUQ01COX6B No results +4377 JY8QFUQ01BGQVH No results +4378 JY8QFUQ01CLSNL productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 818 86.98 187/215 nt Homsap IGHJ1*01 F (see comment) 188 84.62 44/52 nt Homsap IGHD1-26*01 F 1 8 7 13 8.7.13 [1.17.38.11] CVGVGVGSSVSFQYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcactgtcaataacaactacatgggttgggtccgccaggctccagggaaggggctggagtgggtctcgactatttattacggtggcaccacatattacgcagactccgcgaagggccgattcaccatctccagagacacctccaggaacacactttttcttcagatgaacagcctgagaagcgacgacacggctctatattattgtgtgggagtcggagtgggatcttcagtctccttccaatactggggccagggcacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4379 JY8QFUQ01AUVES No results +4380 JY8QFUQ01AO9JD unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgaaccggtgacggtgtcgtggaactcag +4381 JY8QFUQ01BK60E No results +4382 JY8QFUQ01C4PDI No results +4383 JY8QFUQ01CKO6K No results +4384 JY8QFUQ01BDCRM No results +4385 JY8QFUQ01BOEKT unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 126 54.81 74/135 nt 8 8 X 8.8.X [2.17.10.X] null - No rearrangement found gcctctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +4386 JY8QFUQ01BVKEQ No results +4387 JY8QFUQ01CZSZQ No results +4388 JY8QFUQ01ANV1B unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-25*01 F 3 8 7 X 8.7.X [1.17.38.11] CMNELGYCSGG# out-of-frame - in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcagtaccaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagtaaAtttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccttatattactgtatgaacgaactcggatattgtagtggtgggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4389 JY8QFUQ01AVP8E productive Homsap IGHV3-72*01 F 1088 98.66 221/224 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-15*01 F 1 8 10 8 8.10.8 [1.17.38.11] CLRPPRYDPW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4390 JY8QFUQ01AVPBF productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4391 JY8QFUQ01BO6U2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctgtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4392 JY8QFUQ01CK7KF No results +4393 JY8QFUQ01A3N6V No results +4394 JY8QFUQ01APYTK unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt 88.58 194/219 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'TG' (2 nucleotides at position 39 to 40 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); atgtctggattcacAgtttagaagctattccatgaattTGgggtccgccaggctccagggaaggggctggagtgggtctccgctgttagtgataCctggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4395 JY8QFUQ01BG7PE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDPGNYWGYYYDSW in-frame + gtctggattcacctttagtgattatgccttgagctgggtccgccagactcccgggaaggggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgagagatccgggaaattattggggatactattatgactcttggggcctgggaaccctggtcgccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4396 JY8QFUQ01CA7GK productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CATSPSVGSTTVGYW in-frame + ctctggattcacctttagaaactattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgacagatggaggtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgccacatcccctagcgtgggatctacgacggtgggctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +4397 JY8QFUQ01ABJ2H unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 320 72.44 92/127 nt 8 8 X 8.8.X [1.17.8.X] null - No rearrangement found Low V-REGION identity (72,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttaacaactatgccatgggctgggtccgccaggctccagggaaggggttggagtgggtctcatctattagtactagtggtcatcgcctgcctggtccagggcttcttccccca +4398 JY8QFUQ01AEX25 productive (see comment) Homsap IGHV3-11*01 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARGYSYGCFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'GGAGGGACT' (9 nucleotides at position 89 to 97 in the user submitted sequence), (do not cause frameshift); ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcaaacatcaatagtGGAGGGACTagtgggaggaccatatattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagaggatacagctatggctgctttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +4399 JY8QFUQ01C0WB8 No results +4400 JY8QFUQ01CGRI4 No results +4401 JY8QFUQ01AOVXH unproductive Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CLAEVGGRQFDN## out-of-frame + Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccaggggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4402 JY8QFUQ01BSYCR No results +4403 JY8QFUQ01CS0U6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4404 JY8QFUQ01AQUGR unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4405 JY8QFUQ01DE7BX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4406 JY8QFUQ01BEJQP productive Homsap IGHV4-61*02 F (see comment) 681 79.09 174/220 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-9*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARERDRSIGGASELDSW in-frame + Low V-REGION identity (79,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctcttctgtccccataagcagtggtggttactattggaactggatccggcagcccgccgggaaggggctggagtggatcggacgtgttgacagtaatgggttcgtcaggtacaacagttccctcaagagtcgactttctatgtcggtggacatgtccaagagtcaggtctccctgaggttgaggtctgtgatcgccgcggacacggccgtatactattgtgcgcgagaacgcgataggtcgattggcggagcgtcagaacttgactcctggggccagggatctctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +4407 JY8QFUQ01A1YIH productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4408 JY8QFUQ01B3ND5 No results +4409 JY8QFUQ01DU4YB productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4410 JY8QFUQ01CRGJG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgtgtcgtggaact +4411 JY8QFUQ01BINTP unknown (see comment) Homsap IGHV3-64*03 F, or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 169 58.78 77/131 nt 8 7 X 8.7.X [1.17.10.X] null + No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggcaacgtggtcgtcgcatgcctggtccagggcttcttccc +4412 JY8QFUQ01CZQLG No results +4413 JY8QFUQ01BUEG5 productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 591 95.38 124/130 nt 94.62 123/130 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 X 11 8.X.11 [1.3.31.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 38 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagtaaccattggatgaactggggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4414 JY8QFUQ01AWQNO unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 656 78.14 168/215 nt 76.74 165/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (78,14% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'CG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) tctggattcacctttaacagccatgccatgagttgggtccgccaggctccCaggggagggggCGtggagtgggtcgcagattctgtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactatttccccgaaccggtgacggtgtcgtggaactcag +4415 JY8QFUQ01A6QI8 No results +4416 JY8QFUQ01CUORM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARAGYCNNGVCYSSYFDFW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccggggaaggggctggtgtgggtctcacgtatgaatagtgatggcagtgacataaggtacgcggactccgtgaggggccgattcaccatctccagagacaacaccaagaacacgctgtatctacaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagcgggatattgtaataatggtgtatgctactccagttactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +4417 JY8QFUQ01DIBA9 No results +4418 JY8QFUQ01B7IH4 No results +4419 JY8QFUQ01BZUOB productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 937 92.24 202/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gcctctggatcaccctttggttattGatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4420 JY8QFUQ01DTZGD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD6-25*01 F 1 8 8 8 8.8.8 [1.17.38.11] CAKFPSISGW in-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaattcccctctatcagtggctggtacacgccaaaactggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +4421 JY8QFUQ01A3CVF productive Homsap IGHV3-48*03 F, or Homsap IGHV3-48*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-74*03 F (see comment) 393 78.46 102/130 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 X 5 17 X.5.17 [X.X.38.11] CVRDSSPSGYARYESMDVW in-frame + Low V-REGION identity (78,46% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcagcctcacttcctatggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtagcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagtggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcagg +4422 JY8QFUQ01CJR1R productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); ttctggaGtacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4423 JY8QFUQ01C0YWV productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 922 90.22 203/225 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-11*01 ORF 2 8 10 22 8.10.22 [2.17.38.11] CATDRPYYKNAAGRLWYYYGMDVW in-frame - tgctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaacgctgctggccgactctggtattactacggtatggacgtttggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +4424 JY8QFUQ01C9GA0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1017 96.77 210/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKDRITIFSYNWFDPW in-frame + ctctggattcagttttagttcttatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4425 JY8QFUQ01BFMSP No results +4426 JY8QFUQ01BXBXN unknown (see comment) Homsap IGHV3-23*05 F 92 54.37 56/103 nt 8 8 X 8.8.X [1.17.X.X] null + No rearrangement found stop codons tctggattcgtctttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4427 JY8QFUQ01B54JA No results +4428 JY8QFUQ01AF3OP No results +4429 JY8QFUQ01DCEOK unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 845 88.37 190/215 nt 87.91 189/215 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-25*01 F 2 7 8 X 7.8.X [1.17.38.11] CASFRVLESGY## out-of-frame - in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift) tctggattcacattcggagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactgggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4430 JY8QFUQ01DQ43M No results +4431 JY8QFUQ01CO8R0 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagTcccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtctctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcttctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggcttcttccca +4432 JY8QFUQ01A2FAU productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 94.17 210/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaaGtatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4433 JY8QFUQ01BUBB2 productive Homsap IGHV3-9*01 F 1053 98.62 214/217 nt Homsap IGHJ6*02 F (see comment) 265 91.94 57/62 nt Homsap IGHD4-11*01 ORF 3 8 8 17 8.8.17 [1.17.38.11] CAKETTLTHPYYDYAMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagtggtagcataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagctctgaggacacggccttgtattactgtgcaaaggaaactacactgacgcatccctactacgactacgctatggacgtctggggccaggggaccacggtcaccgtctcctcagggagtgcatccgccccaaccc +4434 JY8QFUQ01CYYF8 productive Homsap IGHV3-74*03 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKVDSDGWHGTIDRW in-frame + ctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggatagcgatggctggcacggaacaatagaccgctggggccagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaagg +4435 JY8QFUQ01A7WE6 No results +4436 JY8QFUQ01DLG3Q No results +4437 JY8QFUQ01CLBE1 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 83 51.54 67/130 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcatcttcagtgactactacatgacctggatccgccaggctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4438 JY8QFUQ01DUBJT unproductive (see comment) Homsap IGHV4-61*02 F 1005 95.45 210/220 nt 94.55 208/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 2 10 7 X 10.7.X [1.16.38.11] CARAGKQDFLEWLF#DDW out-of-frame - stop codons in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tctctggtggctccatcggcagtggtagttattactggagctggatccgcagcccgccgggaagggactggaataccttgggcgtatctataccagtgGggagcaccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgctgacacggccatttattactgtgcgagagcggggaaacaggactttttggagtggttattctgacgactggggccagggaaccctggtcatagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4439 JY8QFUQ01CWM41 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4440 JY8QFUQ01B33QK productive (see comment) Homsap IGHV4-61*02 F (see comment) 779 84.4 184/218 nt 83.03 181/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 9 7 13 9.7.13 [1.17.38.11] CARAKDHDDYLVDPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 37 of V-REGION: 'CTT' (3 nucleotides at position 28 to 30 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 3 nucleotides (from position 27 in the user submitted sequence), (do not cause frameshift) tctctggtgcctccatcactagtggtaCTTactactggagttggttccggcagcccgccgggaagacactggaatgggttgggcgtatctatacaactgggagcacctattacaaTcccctctctcaaaagccgagtcaccgtttcagtcgacgagtcccagaatcagctcttcctggacctgacttctgtgaccgccgcggacacggccgtctacttctgtgcgcgagctaaggaccacgatgactacctggtcgacccctggggccaggggatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4441 JY8QFUQ01ARVQK No results +4442 JY8QFUQ01CN1JX No results +4443 JY8QFUQ01BQ1Q3 No results +4444 JY8QFUQ01DJHPC No results +4445 JY8QFUQ01BODJI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKNRGSAMADWYFDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'ATG' (3 nucleotides at position 87 to 89 in the user submitted sequence), (do not cause frameshift); ctctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattactaATGgtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttatttctgtgcgaaaaatagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +4446 JY8QFUQ01B9FB8 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 762 83.18 183/220 nt 82.73 182/220 nt Homsap IGHJ1*01 F (see comment) 107 67.31 35/52 nt Homsap IGHD3-3*01 F 1 10 7 X 10.7.X [1.17.37.11] CARRWSGTYPFAS# out-of-frame - Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 210 in the user submitted sequence), (cause frameshift) tctctggtggctcactcagaagtagtagtcaccattggggctggattcgtcagtcccccgggaaggggctggagtggcttgggactgtcgactttcgtgggaccacccactacaacccgtccctcatgggtcgactcacgatatccgtcgacgcgcccaagagtcaaatgtccctgcacttgagctctgtgaccgccgcagacacggcttttacttctgtgcgagacgctggagtgggacttatccgtttgcctcctgggccagggcatcccggtcatcgtctccccagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4447 JY8QFUQ01AVK6F productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 678 79.91 171/214 nt 79.44 170/214 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) ctctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +4448 JY8QFUQ01CPETI No results +4449 JY8QFUQ01ALJH7 No results +4450 JY8QFUQ01BBE54 productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt 97.33 219/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctaccaaGcagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4451 JY8QFUQ01B85AM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + tccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4452 JY8QFUQ01DKDK7 No results +4453 JY8QFUQ01DRSWV No results +4454 JY8QFUQ01AFRNE unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 705 91.07 153/168 nt 8 8 X 8.8.X [X.17.23.X] null + No rearrangement found ggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctg +4455 JY8QFUQ01CG46A unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +4456 JY8QFUQ01DID0M productive (see comment) Homsap IGHV3-7*01 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 192 to 192 in the user submitted sequence), (cause frameshift); cctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagcCcccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +4457 JY8QFUQ01AT1ET unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 606 75.7 162/214 nt 74.77 160/214 nt 7 8 X 7.8.X [1.16.38.X] null + No rearrangement found Low V-REGION identity (75,70% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaagggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4458 JY8QFUQ01C26ES productive (see comment) Homsap IGHV4-4*07 F 844 88.73 189/213 nt 87.79 187/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 7 11 8.7.11 [1.17.37.11] CARSGWDNQFDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'TGGCAC' (6 nucleotides at position 22 to 27 in the user submitted sequence), (do not cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 109 in the user submitted sequence), (cause frameshift) ctctggtgtcgccaccagtagTGGCACttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaaccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4459 JY8QFUQ01DBD5L productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccccca +4460 JY8QFUQ01AL3HV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4461 JY8QFUQ01BV960 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 847 87.67 192/219 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD2-8*01 F 1 8 8 19 8.8.19 [2.17.38.11] CAKVFQVPGEHHSYYYGMNAW in-frame - gcctctggattcatctttactaactatgccatgagttgggtccgccaggctccagggaagggggctgagtgggtctcaactatcagtgccaatggaggcaacacatactacgcggactccgtgaagggccgattcaccatctccagagacaactccaagaacacagtggatatgcaaatgaacagcctgaaagccgaggagacggccgtctattattgtgcgaaagtcttccaggtgcctggcgaacatcactcctactactatggtatgaatgcctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4462 JY8QFUQ01DOBPZ unproductive Homsap IGHV3-72*01 F 1083 98.65 220/223 nt Homsap IGHJ6*04 F (see comment) 108 66.67 36/54 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYDP## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4463 JY8QFUQ01BUOBI No results +4464 JY8QFUQ01AN9G4 No results +4465 JY8QFUQ01C55O4 productive (see comment) Homsap IGHV3-11*01 F (see comment) 712 80.82 177/219 nt 79.91 175/219 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-25*01 F 2 8 8 11 8.8.11 [2.17.38.11] CVRDRSRGIADPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 169 to 169 in the user submitted sequence), (cause frameshift); acctctggattcatcttcactgacttctggatgagttGgggtccgcctgactccagggaagggcctcgagtgggtttcgtttataagtgggagtggcaatagtgtctggtatgcagactctgtgaagggccgattcactatctccagggacaacgccaagaatttaatCatttttggagatgaacagcctgagagtcgaggactcggccacatattattgtgtgagagaccgcagcaggggaatagcagatccttggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4466 JY8QFUQ01DEFN6 No results +4467 JY8QFUQ01DPT7F unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [1.17.38.11] CANASPLYNWN#YFYYYGMDVW out-of-frame + ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctcccccctgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtggaactca +4468 JY8QFUQ01CXGNA productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGcctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4469 JY8QFUQ01AHYMR unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 190 100.0 38/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found tctggattcaccttcagtagctactggatgcactgggt +4470 JY8QFUQ01DBZNN productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +4471 JY8QFUQ01DI3WZ No results +4472 JY8QFUQ01BU96X No results +4473 JY8QFUQ01AQDC9 No results +4474 JY8QFUQ01B0L20 No results +4475 JY8QFUQ01CQB3G productive Homsap IGHV3-74*03 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKVDSDGWHGTIDRW in-frame + ctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggatagcgatggctggcacggaacaatagaccgctggggccagggagtcctggtcaccgtctccgcagcatcccctgaccagcccctaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaag +4476 JY8QFUQ01B8LWB productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 926 92.56 199/215 nt 92.09 198/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 77 in the user submitted sequence), (cause frameshift) tctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggcgtggagtgggtctctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +4477 JY8QFUQ01BOPD4 No results +4478 JY8QFUQ01CX0BC productive Homsap IGHV3-7*01 F 940 93.06 201/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAYFSTGYW in-frame + tctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +4479 JY8QFUQ01C8ASE productive Homsap IGHV3-48*03 F 792 85.25 185/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [1.17.38.11] CVRQTGDYYFFGLDVW in-frame - ctctggattcgccttcaaaagttttaacatgaattgggtccgccaggcttcagggaaggggccggagtggattgcatacattaatggaagagggactaacatctactatgcagactctgtgaagggccggttcaccatctccagagacaacgcccagaacgcagtgcatctgcagatggaccgcctgagagtcgaggacacggccctatattactgtgtgagacaaactggagactactatttcttcggtctggacgtctggggccaaggaaccacggtcaccgtctcttcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4480 JY8QFUQ01CJ77N No results +4481 JY8QFUQ01AD2TV No results +4482 JY8QFUQ01BWW8O productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.14 211/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctaCctggagctggatccggcagTcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4483 JY8QFUQ01C2XJR productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4484 JY8QFUQ01AVLXC No results +4485 JY8QFUQ01CGGWD unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 97 52.67 69/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +4486 JY8QFUQ01A942D No results +4487 JY8QFUQ01AHP3S productive Homsap IGHV4-4*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [1.17.38.11] CARGKDYYDTTGSLEDGFDIW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctctggtggctccataagaagttactattggagttggatacggcactccgccgggaagggactggagtggatcgggcgcatatatgacagtggtagtacaaactacaatccctccctcaagagtcgagtcagcatgtcagtggacacgtccaagaaccaggtctccctgaagttgatctctgtgaccgccgcggacacggccatgtattattgtgcgagagggaaggattactatgatacaactggctccctcgaggatggttttgatatttggggccaagggacgatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccgctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +4488 JY8QFUQ01DOREV productive Homsap IGHV3-11*01 F 114 61.84 47/76 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 X X 8 X.X.8 [X.X.25.11] CTRRGFMDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ccggattcactttagtgactattggatgagttggatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4489 JY8QFUQ01A9V5D productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggGggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +4490 JY8QFUQ01B2FPL productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 877 89.81 194/216 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAARIDSGHYWNAFDIW in-frame - tctggatccaattttaactacgactggatcggctgggtgcgccagatgcccggtaaaggcctggagtggatgggaatggtctatgttggtgactctgatgctagatacagcccgtcctcccaaggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtgggacagcctgaagaccttggacaccgccaagtattactgtgcggcgagaattgatagtggtcattactggaatgctttcgatatatggggccaagggacgatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4491 JY8QFUQ01BB098 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.37.11] CANEVGYCSGGG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtggggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4492 JY8QFUQ01BW8IT productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt 92.79 206/222 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.37.11] CARGAPFYDS (see Functionality comment) in-frame - Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 182 in the user submitted sequence), (cause frameshift) ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4493 JY8QFUQ01B07DP unproductive Homsap IGHV3-7*01 F 887 89.45 195/218 nt Homsap IGHJ1*01 F 134 73.08 38/52 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CVVSSGWLFHY## out-of-frame + cctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactgggggccagggctcccgggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4494 JY8QFUQ01CNNJJ productive (see comment) Homsap IGHV3-11*01 F 867 89.72 192/214 nt 88.79 190/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.16.38.11] CARDPYCSSTNCYPYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) cctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaagggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4495 JY8QFUQ01B4D86 No results +4496 JY8QFUQ01A3R50 unproductive Homsap IGHV4-39*02 F (see comment) 762 83.18 183/220 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD2-15*01 F 3 10 7 X 10.7.X [1.17.38.11] CATIVPSSVTALINDQGRFYFDH## out-of-frame + Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccagaaccggtgacggtcgtcgtggaactcag +4497 JY8QFUQ01DAQHJ unproductive Homsap IGHV3-11*01 F 867 89.72 192/214 nt 88.79 190/214 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD2-2*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDPYCSSTNCYPY## out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggatTtcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactgggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4498 JY8QFUQ01A4RES No results +4499 JY8QFUQ01DS3ZC unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4500 JY8QFUQ01A92C9 productive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 784 86.19 181/210 nt 84.76 178/210 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [X.16.37.11] CAKHPLRSTSGHSYLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 72 of V-REGION: 2 nucleotides (from position 118 in the user submitted sequence), (cause frameshift) ggatacatattcaccgacctttatatacactgggtgcgacaggcccctgacaagggcttgagtggatCgggatccatcaatcccaacagtggtgtcacaacctacgaagagaagtttcgggcaggtcaccatgaccagggacacgtccatcactacagcctacatggaactgacaagccttacatcagacgacacggccgtatattactgtgcgaaacatcctcttcgatcaacaagtggacattcctacttagattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4501 JY8QFUQ01AI5JW productive Homsap IGHV3-48*01 F 810 86.18 187/217 nt Homsap IGHJ6*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 1 8 8 8 8.8.8 [1.17.38.11] CVRGAGLDVW in-frame + ctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaggggctggagtgtgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctggacgtctggggccaagggaccacggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4502 JY8QFUQ01BJH23 No results +4503 JY8QFUQ01A9XW7 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 316 60.27 132/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null - stop codons no junction found Low V-REGION identity (60,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. gcctctggattcacatttagcaactatgccatgagctgggtccgccaggctccagggaaggggccggagtgggtctcagctattactggtcttgatggtagaacattctacgcagactcgtatattattgtgcgaaagagatagcagtgagtggtgaggggcgttggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4504 JY8QFUQ01DUXII No results +4505 JY8QFUQ01CPIP8 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPGGNCLL*WW*#CYDPW out-of-frame + stop codons ctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggaattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4506 JY8QFUQ01DCXHM unproductive (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F (see comment) 413 80.8 101/125 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 X 3 X X.3.X [X.X.38.11] CASFAGPVVVTL*WLLVRLT#YCDYR out-of-frame + stop codons Low V-REGION identity (80,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgcattcaccgtcagtaggctccgtgacgggccgagtcatcatctccagagagaatgcccagaactccgtgtatcttccactgaacagcctgagagccgggaacacggctgtgtatcactgcgcaagttttgctggccctgtggtggtgactctatagtggctgttggtccgtctgaccactactgtgactaccggggcctgggaaccccggtccccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +4507 JY8QFUQ01C21XG unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag +4508 JY8QFUQ01CWJQ8 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 297 59.45 129/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found stop codons Low V-REGION identity (59,45% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4509 JY8QFUQ01B6XM5 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctggatccgccaagctccggggagggcgtggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4510 JY8QFUQ01BPWE6 No results +4511 JY8QFUQ01AJ3CD productive (see comment) Homsap IGHV3-NL1*01 F (see comment) 353 74.81 98/131 nt 74.05 97/131 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 3 X 5 14 X.5.14 [X.X.38.11] CVRGRDGVNFGEMDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (74,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); cctctggattcagctttttcaattatggcatgaactggggccgattcgccatctccagagacgattcgaGgggacacactgtatctccaaatggacagcctgagagccgaggacacggctgtgtattactgtgtgaggggtagagatggtgttaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4512 JY8QFUQ01B6STP No results +4513 JY8QFUQ01BETLC productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame + ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4514 JY8QFUQ01DFE9Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctncctggtcaaggactcanttccccgaaccggtgacggtcgtgcgtggaactcag +4515 JY8QFUQ01CDOYZ No results +4516 JY8QFUQ01BMXPA unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 186 97.44 38/39 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found cctctggattcatcttcagtagctactggatgcactggg +4517 JY8QFUQ01CPU5E productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4518 JY8QFUQ01C8PPT productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4519 JY8QFUQ01C0KOY productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 661 78.24 169/216 nt 77.31 167/216 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.16.38.11] CAREDIVREGLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (78,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) gtctggtggctccatcgccacttatcattggtggAacttgggtccgccagaccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctgatcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4520 JY8QFUQ01AOJU2 productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttcccccag +4521 JY8QFUQ01BX5TF No results +4522 JY8QFUQ01B3KFV No results +4523 JY8QFUQ01CRUFY No results +4524 JY8QFUQ01B8V2B No results +4525 JY8QFUQ01BHZ3N productive (see comment) Homsap IGHV3-30*01 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [1.17.38.11] CVKNDLSWGTIEHYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcacgttcaacatttatgGgtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcgtcagcatcccgaccagccccaaggtcttcccgctgagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4526 JY8QFUQ01CYMH8 No results +4527 JY8QFUQ01DK27R No results +4528 JY8QFUQ01BX0QN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAREGGRGSSSEDYFDYW in-frame + ctctggattcaccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaatggtgcttacatatactacgcagactcaatggagggccgattcaccatctccagagacaacgccaggaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgcgagagggggggcggggcagttcgtcggaagactactttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4529 JY8QFUQ01AW72P No results +4530 JY8QFUQ01C8XQH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.16.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctgtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4531 JY8QFUQ01BY9RP No results +4532 JY8QFUQ01AXCGR productive Homsap IGHV3-7*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame - cctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4533 JY8QFUQ01CS9VK productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 773 83.04 186/224 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 13 8.10.13 [1.17.38.11] CATDSPTGYYAFDVW in-frame + Low V-REGION identity (83,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctgggttcgttttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4534 JY8QFUQ01CWELI No results +4535 JY8QFUQ01AFRYK No results +4536 JY8QFUQ01BO2RQ No results +4537 JY8QFUQ01CMN6I productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDLTGYSSERNYW in-frame + ctctgggttcaccttcagtcgttatagcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggtcttctactgacatatattatgcagactcagtgaagggccgattcaccatttccagagacaacgccaagaactcactgttcctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4538 JY8QFUQ01B3WLK No results +4539 JY8QFUQ01B38SJ unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDLFQVSTTYFDY# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactgggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaaactc +4540 JY8QFUQ01BKK0T unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 437 93.0 93/100 nt 8 7 X 8.7.X [1.17.X.X] null + No rearrangement found tctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgaca +4541 JY8QFUQ01ANCB8 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggcccaggggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4542 JY8QFUQ01A9WJB No results +4543 JY8QFUQ01DRHLE productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame + tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4544 JY8QFUQ01BAAAQ No results +4545 JY8QFUQ01AKWHE unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 792 84.79 184/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4546 JY8QFUQ01BDL7E productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4547 JY8QFUQ01DNGMS No results +4548 JY8QFUQ01CUHJM No results +4549 JY8QFUQ01DK466 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 596 86.62 136/157 nt 85.35 134/157 nt 8 8 X 8.8.X [0.16.19.X] null + No rearrangement found in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 74 to 76 in the user submitted sequence), (do not cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tcgggactcatgttagcagctatgccatgacctgggtccgccaggctccagggaagggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaac +4550 JY8QFUQ01C7GDH No results +4551 JY8QFUQ01B0Q4E unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKKTL*FGDLFI#NFDYW out-of-frame + stop codons ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaacattataattcggggacttatttataacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4552 JY8QFUQ01AFYZD unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4553 JY8QFUQ01AVXMW No results +4554 JY8QFUQ01C3IKA productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame - cctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +4555 JY8QFUQ01C58UH No results +4556 JY8QFUQ01DACGY No results +4557 JY8QFUQ01C4VWZ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4558 JY8QFUQ01BF7W4 No results +4559 JY8QFUQ01AE7Y3 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + cctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +4560 JY8QFUQ01DWDNB unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 88 51.91 68/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +4561 JY8QFUQ01CYNJO No results +4562 JY8QFUQ01DLEZW productive (see comment) Homsap IGHV3-7*01 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ3*01 F (see comment) 151 78.0 39/50 nt Homsap IGHD3-16*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARATNADVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 97 of V-REGION: 'N' (1 nucleotides at position 194 to 194 in the user submitted sequence), (cause frameshift); ctctggattcacctttagggggtactggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaccataaatcacgatggaagtcaaatttactatatggaccttgtgaagggccggttcaccatctccagagacaacgccgagacctcactctatttgcaaatgaacaccctgagagccNgaagacacggctgtctattactgtgcgagggcgactaatgccgacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgccagcacccagccagatgggaacgtggtcatcgcctgccctggtccagggcttcttcccccg +4563 JY8QFUQ01BSOKW No results +4564 JY8QFUQ01DBBO3 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 691 80.75 172/213 nt 80.28 171/213 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 78 of V-REGION: 'AG' (2 nucleotides at position 134 to 135 in the user submitted sequence), (cause frameshift); tctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcgaAGtctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4565 JY8QFUQ01BE615 No results +4566 JY8QFUQ01CAYVD No results +4567 JY8QFUQ01BP9LD productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 908 91.63 197/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - cctctgggttcaccgtcagtagcaagttcatgagctgggtccgccagggtccagggaaggggctggagtgggtctcagttacttatcctgatggtactacacattatagagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4568 JY8QFUQ01A9YBA No results +4569 JY8QFUQ01DNHHQ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 930 92.99 199/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-25*01 F 1 8 8 15 8.8.15 [0.17.38.11] CARHEGYNSRYYYFGYW in-frame + tggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4570 JY8QFUQ01ABEDS No results +4571 JY8QFUQ01AWGGY No results +4572 JY8QFUQ01A3FHH No results +4573 JY8QFUQ01DU7IU productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccccca +4574 JY8QFUQ01C33AV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 940 93.06 201/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + tctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4575 JY8QFUQ01BUUH7 No results +4576 JY8QFUQ01AK2QD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVAVGMSGWFDPW in-frame + ctctggattcaccttcagtaactactggatgtattgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggcagtagcacaagctacggggactccgtgaagggccgattcaccgtctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgcgagtcgacgacacggctctatattattgtgcaagaggccgtatagtagcagttgggatgtcaggctggttcgacccttggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4577 JY8QFUQ01DSV8Y productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4578 JY8QFUQ01ALRTE unproductive Homsap IGHV3-66*02 F 898 91.55 195/213 nt 90.61 193/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [1.16.38.11] CAKLADTGEWSNRIFI#W out-of-frame - in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) ctctggattcaccgtcagtagcagcttcatgacttgggtccgccagctccaggaaagggactggagtgggtctCcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatctttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4579 JY8QFUQ01B75FR No results +4580 JY8QFUQ01BYGMF productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame + ctctggattccccttcagcacctatcccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +4581 JY8QFUQ01A3OFB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 3 8 8 15 8.8.15 [2.17.38.11] CAKPAPRGYSGDDIEFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); ctctctggattcacctttaacaactatgccctgagttggttccgccaggctccagggaggggactggagtgggtctcagccgttagtggtagtggtgattatacatattacgcagactccgtgAaagggccggttcaccatttccagagacaattccaagaacacactgtggctgcaaatgaacagactgagagccgaagacacggccgtatattactgtgcgaagcctgccccccgtggatatagtggtgacgacattgagttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4582 JY8QFUQ01BIH1E No results +4583 JY8QFUQ01DKPSN No results +4584 JY8QFUQ01AIKKX No results +4585 JY8QFUQ01CG3LU productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacaatctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4586 JY8QFUQ01B744Z No results +4587 JY8QFUQ01BNC27 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 131 96.43 27/28 nt 8 X X 8.X.X [1.X.X.X] null - No rearrangement found ctctgggttcacctttagcagctatgcc +4588 JY8QFUQ01CXWSD productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 7 12 8.7.12 [1.17.38.11] CARAPGWMNPFDFW in-frame + ctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4589 JY8QFUQ01B56VC productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 952 92.34 205/222 nt 91.89 204/222 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.37.11] CTHLREEMSYEW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 161 in the user submitted sequence), (cause frameshift) ctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4590 JY8QFUQ01CEB97 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 787 85.19 184/216 nt 84.72 183/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD2-21*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARRSGRDGGWFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 82 of V-REGION: 'G' (1 nucleotides at position 148 to 148 in the user submitted sequence), (cause frameshift); tctggattcatctttgccgactatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtcgcagatattaatggaagaggtgctgccgcacactacgcagactccgtgacgggccgcttcaccctctacaaagacGgtttccaagaatacgatgtatctgcaaatgaggaccctgagagacgacgacacggccaaatattactgtgcgagacgaagtgggcgtgatgggggctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4591 JY8QFUQ01BZ966 productive Homsap IGHV3-48*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDRGGSAYPIFDYW in-frame + ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4592 JY8QFUQ01DTO1H No results +4593 JY8QFUQ01CUJHH No results +4594 JY8QFUQ01BTCL3 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 999 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPAGGSGAYEYW in-frame + ctctggattcaagtttgatgattccggcatgagctgggtccgccaagctccagggaaggggctggagtgggtctctggtattaattggaatggtggtaagacaggttatggagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatttgcaaatgaacagtctgagagccgaggacacggccttgtattactgtgcgagaggccccgccgggggatctggcgcatatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgcntgacgcctcgacagcacccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttcc +4595 JY8QFUQ01DAUI5 productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 15 8.8.15 [0.17.38.11] CARQRGPGIGTVGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgcgacagagaggtcccggtatagggacagttggcttggactattggggccagggtaccctagtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +4596 JY8QFUQ01C8CME productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4597 JY8QFUQ01BRAAE unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CATSRGAPTGT#FDHW out-of-frame + ctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcaggggagcgccaactggtacccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4598 JY8QFUQ01BCWGQ No results +4599 JY8QFUQ01AX0WG productive Homsap IGHV3-30*01 F 977 94.5 206/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcaccctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcca +4600 JY8QFUQ01AR3M4 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPGGNCLL*WW*#CYDPW out-of-frame + stop codons ctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggaattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagactgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa +4601 JY8QFUQ01AMLPV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 856 88.13 193/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [2.17.38.11] CMNEFGYCSGG# out-of-frame - ggctctggattcacttttagcagccatatgatgacttgggtccgccaggctccagggaaggggctggaatgggtcgcaagtattcgtgccagtggtggtaggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgttgtatttgcaaatgtacagtctgagagtcgaggacacggccttatattattgtatgaacgaattcggatactgtagtggtgggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4602 JY8QFUQ01DP1EJ productive (see comment) Homsap IGHV3-11*01 F 862 89.67 191/213 nt 88.73 189/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.16.38.11] CARDPYCSSTNCYPYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaagggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4603 JY8QFUQ01B7HZR productive Homsap IGHV3-64*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + cctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4604 JY8QFUQ01A744W No results +4605 JY8QFUQ01BFKLI No results +4606 JY8QFUQ01DA5ZG productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 962 94.42 203/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [0.17.38.11] CARDTLEVVSNMDDAFDLW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggcccaaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgggtccagggcttcttccccca +4607 JY8QFUQ01CC2VB unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 796 85.65 185/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [1.17.38.11] CATYGRFSF#SLDYW out-of-frame + tctggattcgacttcagtagttatggcttccattgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctcccttgactactggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4608 JY8QFUQ01ANF5H No results +4609 JY8QFUQ01CJ5A2 No results +4610 JY8QFUQ01C6UTW No results +4611 JY8QFUQ01AS4LQ No results +4612 JY8QFUQ01DTPMH productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 894 91.12 195/214 nt 90.65 194/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-18*01 F 1 8 8 15 8.8.15 [0.17.38.11] CAIVDTNLVSATGKDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcagcaactactatagacactgggtgcgacaggCcccctggacaagggcttgagtggatgggaatgatcaaccctagtagtgattacaaatattacgcacagaaatttcagggcagagtcaccatgaccagggacacgtccacgagcacagtcttcatggagctgagtagcctgagatctgacgacacggccgtgtattattgtgcaatagtggacacaaatttggtttcggcgaccggtaaagactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4613 JY8QFUQ01DUKA3 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 987 94.55 208/220 nt 93.64 206/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAGHLLGDPFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'T' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift); gggttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctaTtcctggtgactctgacaccagatacagtccgCtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag +4614 JY8QFUQ01AXJ22 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 126 54.81 74/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcagatttagcagctatgccatgagctgggtccgccagactccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4615 JY8QFUQ01AW69P unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 977 94.5 206/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARGQNGYKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4616 JY8QFUQ01AIWLS No results +4617 JY8QFUQ01DSIM2 No results +4618 JY8QFUQ01CVS2H unproductive Homsap IGHV4-61*02 F 884 89.14 197/221 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD5-24*01 ORF 1 10 7 X 10.7.X [1.17.38.11] CARDFGGSYNLVAY## out-of-frame + tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4619 JY8QFUQ01A4O68 No results +4620 JY8QFUQ01CBJ8O No results +4621 JY8QFUQ01BH6PY No results +4622 JY8QFUQ01DTY3T No results +4623 JY8QFUQ01CT148 unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacaacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag +4624 JY8QFUQ01AEZHH No results +4625 JY8QFUQ01AZUBY productive Homsap IGHV3-9*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-11*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKESGVTGATGFDFW in-frame + ctctgggttcaactttgatgcttatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattaattcgaatggtggtaacatagactatgtgggctctgtgaagggccgattcaccatctccagagacaacgccaagaagtccctatatctgcaaatgaacagtctgagacctgaggacacggccttgtattactgtgcaaaagagtctggagtgactggcgcaactggatttgacttctggggccagggagccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttgcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc +4626 JY8QFUQ01AVET2 productive Homsap IGHV3-66*02 F 858 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 12 8.7.12 [1.17.38.11] CARQTAPFGYFEDW in-frame + ctcggaattctccgtcagtgacagtcacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtagtgcatattatgcagactccgtgaggggccgattcaccatcgccagagacaaatctaagaacgtgttgtatcttcaaatgaacagtctgagacctgaggacacggctgtgtactactgtgcgagacagactgccccttttgggtactttgaggactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4627 JY8QFUQ01C69T5 unproductive (see comment) Homsap IGHV3-66*02 F (see comment) 764 84.19 181/215 nt 83.72 180/215 nt Homsap IGHJ6*02 F (see comment) 192 80.0 48/60 nt Homsap IGHD3-3*02 F 1 8 7 X 8.7.X [2.16.38.11] CARH*W#YALDVW out-of-frame - stop codons Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 81 in the user submitted sequence), (cause frameshift) gtctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaggggctggagtgggtctcagtcttattagtactggcactgcatactacgcagactccgtgaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcattaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +4628 JY8QFUQ01BA5U7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +4629 JY8QFUQ01CK4GI No results +4630 JY8QFUQ01CKJ8Y unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*05 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*12 F or Homsap IGHV3-30*13 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*02 F or Homsap IGHV3-33*05 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 144 56.3 76/135 nt 8 8 X 8.8.X [1.17.11.X] null - No rearrangement found tctggattcacgttcagtggctatggcatgcactgggtccgccaggctccaggcaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +4631 JY8QFUQ01BQ1LV unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 689 94.16 145/154 nt 8 8 X 8.8.X [2.17.16.X] null - No rearrangement found gcctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatg +4632 JY8QFUQ01AQBZ1 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4633 JY8QFUQ01AV3HD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4634 JY8QFUQ01AUXJ6 No results +4635 JY8QFUQ01AVEP9 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagcccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +4636 JY8QFUQ01C2MEG unknown (see comment) Homsap IGHV3-7*01 F 1002 96.73 207/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tggattcaccttcaggagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgacaaattctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaacccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4637 JY8QFUQ01C28IZ No results +4638 JY8QFUQ01DGW1K No results +4639 JY8QFUQ01ANJ4I unknown (see comment) Homsap IGHV3-23*05 F 121 54.48 73/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcacctttagcaactatgccatgagctgggtccgccaggctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4640 JY8QFUQ01DO7YT No results +4641 JY8QFUQ01BZBYT No results +4642 JY8QFUQ01BCZ8G No results +4643 JY8QFUQ01AYAUS productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt 91.4 202/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgGggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4644 JY8QFUQ01AGWXH productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + ctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +4645 JY8QFUQ01AOV3G No results +4646 JY8QFUQ01ALMBP unproductive Homsap IGHV3-9*02 F (see comment) 733 82.41 178/216 nt 81.94 177/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 7 X 8.7.X [1.17.38.11] CVKDKDKVGATLAIIP#FDFW out-of-frame + Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 97 in the user submitted sequence), (cause frameshift) ctctggattcaaccccgaaaactttgccatgcactgggtccgacaagttccagggaagggcctgaagtgggtctcaggtataaattggaatggacgaaaacaggatatgcggagtctgtgaggggccggttcaccatctccagagacaatgacaagaacgtcctttctttgcaaatgaccaatttggggactgaggacacggccttctatttttgtgtgaaagataaggacaaagtgggggccacactggccattatcccacgtttgacttctggggccagggagccctggttaccgtcgcatcagcctccaccaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4647 JY8QFUQ01A6WHV unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found cctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +4648 JY8QFUQ01DHOIV No results +4649 JY8QFUQ01DXHZL No results +4650 JY8QFUQ01B5QSA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +4651 JY8QFUQ01CH0DW No results +4652 JY8QFUQ01CHRZT unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcnacctgactactgggggcccagggaactttggtcaccgtcgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgccagcacccagccagatggaacgtggtcatcgcctgctggtccagggcttcttccccca +4653 JY8QFUQ01AZ96F No results +4654 JY8QFUQ01DLUBY No results +4655 JY8QFUQ01A9DTT productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 804 86.45 185/214 nt 85.51 183/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.37.11] CATLRGGTFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttataCttaattatgttggggacaccgattacaaccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4656 JY8QFUQ01BZUYN No results +4657 JY8QFUQ01CX6VT productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1020 97.66 209/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARGGGYYFVAIDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +4658 JY8QFUQ01DWS1A unknown (see comment) Homsap IGHV3-7*01 F 945 93.09 202/217 nt 92.63 201/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 53 of V-REGION: 'TG' (2 nucleotides at position 73 to 74 in the user submitted sequence), (cause frameshift); ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtggggTGggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4659 JY8QFUQ01CC7RN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATSRGSANWYPFDHW in-frame - cctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4660 JY8QFUQ01DW6R5 productive Homsap IGHV3-9*01 F (see comment) 765 83.87 182/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgagggaccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4661 JY8QFUQ01BPWL9 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 454 72.63 130/179 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (72,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4662 JY8QFUQ01CAK86 No results +4663 JY8QFUQ01AUWPD No results +4664 JY8QFUQ01BWI2D productive Homsap IGHV3-30*01 F 819 86.64 188/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD5-12*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDFDTDDVGTYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcatcttcgatagttatgctctgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttgtttcatatgatggaaaatataagcaatatgcagattctgtggagggccgattcaccatctccagagacaactccaagaacacaggatatctgcaaatgaacagcctgacatctgacgatacggctgtgtatttttgtgcgagagacttcgatactgacgacgtgggcacctactggggccggggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4665 JY8QFUQ01B2HHQ No results +4666 JY8QFUQ01AQQIB No results +4667 JY8QFUQ01CKXD4 unproductive Homsap IGHV3-7*01 F 1012 96.76 209/216 nt 96.3 208/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSGFTRR#YW out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); tctggattcaGcctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4668 JY8QFUQ01BAP04 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 112 53.73 72/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4669 JY8QFUQ01CGWES No results +4670 JY8QFUQ01A6PW0 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggcaantca +4671 JY8QFUQ01DCD36 productive Homsap IGHV3-7*01 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [2.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame - gcctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4672 JY8QFUQ01DIE0Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 103 62.9 39/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggcccaggggaccacggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaa +4673 JY8QFUQ01AIZMG No results +4674 JY8QFUQ01DCCWO No results +4675 JY8QFUQ01DTB7M productive (see comment) Homsap IGHV4-4*07 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 7 9 8.7.9 [2.17.38.11] CARDSGDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); ggtctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtccaaaccagtgggagccCcccactacaacccttccctcaagagtcgagtcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccacttttttctgtgcgagagactccggggactttgactactggggcccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4676 JY8QFUQ01A6I5I No results +4677 JY8QFUQ01DCHOK No results +4678 JY8QFUQ01C101D productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 907 92.02 196/213 nt 91.55 195/213 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CTGNGATSHW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 91 in the user submitted sequence), (do not cause frameshift) tctggattcacctttaacaccgaggccctgacctgggtccgccaggctccagggaaggggctggagtgggtctcagatattagagatagtggaagtaaattctacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacggtgtacctgcaaatgagcagcctgagagccgaggacacggccgtatattactgtacgggtaatggtgcgacttcccactggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4679 JY8QFUQ01DGQES No results +4680 JY8QFUQ01C9YSI No results +4681 JY8QFUQ01AQS9S productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 838 87.21 191/219 nt 86.76 190/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) cctccgggagttcaccttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +4682 JY8QFUQ01C92T9 productive (see comment) Homsap IGHV3-33*05 F (see comment) 748 82.65 181/219 nt 82.19 180/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.17.38.11] CVKGRGYNDYGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); gcgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaatgggctggagtgggtggcgaccatttcatatgatAttaatgaaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4683 JY8QFUQ01A29KU No results +4684 JY8QFUQ01CDA8Y No results +4685 JY8QFUQ01DRVM7 No results +4686 JY8QFUQ01DNU0M No results +4687 JY8QFUQ01BJGIP productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccacaagggcccatcggtcttcccctggcgcctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +4688 JY8QFUQ01A9HX8 productive Homsap IGHV3-7*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARGGGGVHDYW in-frame + ctctggattcacctttagtgactattacatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagccagatggaagtcagaaaaactatgtggactctgtgaagggccgattctccatctccagagacaacgccaagaactcactatatctgcaaatgaacagcctgagagccgaagacacggctgtgtattactgtgcgagagggggaggaggtgttcacgactattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +4689 JY8QFUQ01CX99C No results +4690 JY8QFUQ01CA0N1 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 854 88.84 191/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcgggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4691 JY8QFUQ01A6RCW unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +4692 JY8QFUQ01DO79G productive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4693 JY8QFUQ01A9L1M productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1070 100.0 215/215 nt 99.53 214/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.16.38.11] CARDGIFGGLDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaagggctggtgtgggtctcacgtattaatagtgatgggagtagcacaagctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagacgggatttttggagggcttgactactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaa +4694 JY8QFUQ01BM63P productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 978 94.09 207/220 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAIEHTLPSGQGLGIQYFW in-frame - agcctctggattcaactttaacagctttgccatgagctgggtccgccaggttccagggatggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactccgtgaagggccggttcaccatctccagagacaactccaacaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgatcgagcatacccttccgtccggacagggattagggattcaatatttctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4695 JY8QFUQ01A80HW productive (see comment) Homsap IGHV3-48*01 F (see comment) 759 84.11 180/214 nt 83.64 179/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4696 JY8QFUQ01AOEBD No results +4697 JY8QFUQ01DRPER productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +4698 JY8QFUQ01AT5YH productive (see comment) Homsap IGHV3-23*05 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4699 JY8QFUQ01APV5N unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGVIAVAG#DFDCW out-of-frame + in FR3-IMGT at codon 102 of V-REGION: 'AAAAAAAAA' (9 nucleotides at position 209 to 217 in the user submitted sequence), (do not cause frameshift); ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtaAAAAAAAAAtattactgtgcgaagggggttatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4700 JY8QFUQ01BIK2I productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [2.17.38.11] CVRRGMVAGRYDAFDIW in-frame - gcctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4701 JY8QFUQ01BLB0A productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame - cgtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4702 JY8QFUQ01B7LF9 productive (see comment) Homsap IGHV4-59*10 F, or Homsap IGHV4-61*02 F (see comment) 555 71.62 164/229 nt 71.18 163/229 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 3 8 7 15 8.7.15 [6.17.37.11] CARSVTSRRRGGDFDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (71,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 226 in the user submitted sequence), (cause frameshift) tctccagtggcattgttaatggcgaaggttttggtcgtttctactggaactgggtccggcagatcgacgggcaggggctagagtggatcgggcgtgtttatcgtgatgggatcacaaactacaatccctccttcgggacccgaataagtttgtcgttagactcgtccaagaggcagttttccctggagttacagtctgtgaccgccgcagacacggccttatattttgtgcgaggagcgtgacaagtcggcggcggggcggcgactttgactcctggggccagggactcctggtcaccgtctcatctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4703 JY8QFUQ01A7Y4R No results +4704 JY8QFUQ01ANJ9X productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [2.17.38.11] CASDLGGQKSYW in-frame - ccgtcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +4705 JY8QFUQ01DIW8G No results +4706 JY8QFUQ01CBFBW productive (see comment) Homsap IGHV4-61*02 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 10 6 16 10.6.16 [1.17.38.11] CAIERSRSIGGDGQFDFW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 102 in the user submitted sequence), (do not cause frameshift) tctctggtggccccatcagaggcggtggtttctactggacctggctccggcagtccgccgggaagggcctggagtggatcggacgtatttatgacagtggcagtgactacaatccttctctcaagagtcgagtcaccatgtcagtagacacgtccaagagccagttctccctgaggctgagttctgtggccgccgcagacacggccgtttacttctgtgcgatagaacgtagtagatcgattggcggagacggacaatttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +4707 JY8QFUQ01CCYS6 No results +4708 JY8QFUQ01AW6X6 No results +4709 JY8QFUQ01A7GVL productive Homsap IGHV3-23*05 F (see comment) 447 83.08 108/130 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 X 5 16 X.5.16 [X.X.38.11] CVRYDYSRLHRSNYFGPW in-frame + Low V-REGION identity (83,08% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcatcagttatgactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga +4710 JY8QFUQ01B98ZU No results +4711 JY8QFUQ01BEVYZ No results +4712 JY8QFUQ01BZOK5 No results +4713 JY8QFUQ01B3KH4 productive Homsap IGHV3-9*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + ctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4714 JY8QFUQ01CZ0DT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +4715 JY8QFUQ01CP7VJ productive (see comment) Homsap IGHV4-39*02 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 10 7 12 10.7.12 [1.17.37.11] CASVTTVSMRMKYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 3 nucleotides (from position 108 in the user submitted sequence), (do not cause frameshift) tctctggtggctccatcagcagtgatagttactactggggctggatccgccagtccccagggaaggggctggagtggattgggaatatctattatcgtgggagcacctacaacccatccctcgagagtcggctcaccatgtcggtagacacgtccaggaacctcttctccctgaggctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagcgtgactacggtgtctatgaggatgaaatactggggccggggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4716 JY8QFUQ01A5Z82 No results +4717 JY8QFUQ01DWOVD No results +4718 JY8QFUQ01BJANJ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [2.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) agcctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +4719 JY8QFUQ01ABNBE No results +4720 JY8QFUQ01BTS7A productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 973 92.11 210/228 nt 91.67 209/228 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [2.17.38.11] CARGGNYYDSGGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); tctccgggggacagtgtctctagcagcagtgttgTtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcgaataactatcaagccagacgcatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtatattactgtgcaagagggggtaattactatgatagtggtggtcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4721 JY8QFUQ01C0VEL unknown (see comment) Homsap IGHV3-7*02 F 114 59.52 50/84 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found cctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4722 JY8QFUQ01C7CS6 No results +4723 JY8QFUQ01BEJXS productive (see comment) Homsap IGHV3-72*01 F 988 94.14 209/222 nt 93.69 208/222 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*01 F 3 8 10 15 8.10.15 [1.16.38.11] CSRVGGWVGRADGFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggactcaccttcagtgcccagtacttagactgggtccgccaggctccaggaagggactggagtgggttggccgtattagaagcaaaactaacagttacaccacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattctacgaactcactgtatctgcaaatgaacagcctgaaaaccgaagacacggccgtgtactactgttctagagtcggcgggtgggtggggcgtgctgatggttttgatctgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4724 JY8QFUQ01DDXBA No results +4725 JY8QFUQ01A3LLN unproductive Homsap IGHV3-9*01 F 963 93.55 203/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDAMGGAGDWAAFGI## out-of-frame + ctctggcttcatctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagcgctaccatagaatatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctggaaatcaacagtctgagacctgaagacacggccttatactactgcgcaaaagatgcgatgggaggagctggtgattgggctgcttttggtatctggggcccaggggacaatggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4726 JY8QFUQ01DM6JG productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*04 F 998 96.28 207/215 nt 95.81 206/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-15*01 F 2 8 7 21 8.7.21 [1.17.38.11] CARRIQGHCRGGSCSRNNWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtggttactactggagttggatccgccagcCccccagggaaggggctggagtggattggggaaatcaatcatagtggaagcaccaactacaactcgtccctcaagagtcgagccaccatctcagtagacacgtccaagaagcagttgtccctgaacgtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacggattcaaggacattgtaggggtggtagttgctccaggaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccc +4727 JY8QFUQ01DGZIW No results +4728 JY8QFUQ01ACY54 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctccggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactgggggccagggagtcctgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4729 JY8QFUQ01C8VP6 No results +4730 JY8QFUQ01BHFKT No results +4731 JY8QFUQ01DBO0T productive Homsap IGHV3-7*01 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + gctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4732 JY8QFUQ01CM5IX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4733 JY8QFUQ01DGSNM No results +4734 JY8QFUQ01CM23O productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcca +4735 JY8QFUQ01BUFCX No results +4736 JY8QFUQ01BP8IU No results +4737 JY8QFUQ01DR8BR No results +4738 JY8QFUQ01DVFKE productive (see comment) Homsap IGHV3-7*01 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.16.38.11] CTTTLVWFGEL (see Functionality comment) in-frame + Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggaggggctggagtgggtggccaacataaagGcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4739 JY8QFUQ01BTHPI No results +4740 JY8QFUQ01AKCJN No results +4741 JY8QFUQ01B73XN unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKSPLSVAGTRQNWFD#PG out-of-frame - gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctgggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4742 JY8QFUQ01AK2PL productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 984 95.79 205/214 nt 94.86 203/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CASAPSDSSGYYFSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagttactatatgcactgGggtccgacaggCcccctggacaagggcttgagtggatgggaatgatcaaccctagtggcggaagcacaatctacgcacagaacttccagggcagagttgccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgctagcgccccctctgatagtagtggatactacttttcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaatgatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +4743 JY8QFUQ01CIIEZ unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 89 51.88 69/133 nt 8 8 X 8.8.X [X.17.11.X] null + No rearrangement found stop codons ggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagactgggaacgtggtacgtcgcatgcctggtccagggcttgcttccccca +4744 JY8QFUQ01CYISQ No results +4745 JY8QFUQ01DXGTX No results +4746 JY8QFUQ01BEN0N unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*05 F or Homsap IGHV3-30*13 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 131 83.78 31/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcagcctcacttcctatggcatgaactgg +4747 JY8QFUQ01DRQVG productive Homsap IGHV4-61*02 F (see comment) 655 77.48 172/222 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [2.17.38.11] CARERDRSIGGAAELDSW in-frame - Low V-REGION identity (77,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctccaatgtacccatcagtcgtggaggttactactggaattggatccggcaggccgccgggaaggggctggagtggcttggacgtgttgacagtaatggattcgtcaggtacaattcttccctcaaaagtcgcctttctatgtcactagacacgtccaagaatcagatctccctgatattgaggtctgtgatcgccgcagacacggccgtatatttctgtgcgagggagcgtgataggtcgatcggtggagcggcagaacttgactcctggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +4748 JY8QFUQ01DVBT5 unknown (see comment) Homsap IGHV3-72*01 F 921 90.58 202/223 nt 90.13 201/223 nt 8 10 X 8.10.X [1.17.38.X] null + No rearrangement found in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 131 to 131 in the user submitted sequence), (cause frameshift); ctctggtttccccttcagtgaccacttcatggactgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaGggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctggggccaggggtacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +4749 JY8QFUQ01AY08B productive (see comment) Homsap IGHV3-48*03 F 854 88.84 191/215 nt 87.91 189/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 7 8 13 7.8.13 [1.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 28 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 2 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagttcttatgcatgaactgggtccgcctggtcaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4750 JY8QFUQ01DH1Y5 No results +4751 JY8QFUQ01BTVCR No results +4752 JY8QFUQ01DIG78 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 458 73.03 130/178 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (73,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +4753 JY8QFUQ01DW2E3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4754 JY8QFUQ01B027I No results +4755 JY8QFUQ01CYKIH No results +4756 JY8QFUQ01A9XEC No results +4757 JY8QFUQ01B62LK unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 858 87.0 194/223 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-22*01 F 2 8 10 X 8.10.X [1.17.38.11] VLGILLVIIDS#W out-of-frame - Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccatttcactgacgcctggatgacctgggtccgccaggctccggggagggggctggagtgggttggccgtattaaaagtaaaggtggtggtgggacagcagactatgctgcacccgtgaaaggcagattcgtcatctcaagagatgattcaaggaacacgatgtatctgcaaatgaacagcctaaagagtgaagacacagccatgtattttgtgcttgggatactactggttattatcgactcatgtggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4758 JY8QFUQ01CHI1P productive Homsap IGHV3-74*03 F 828 87.1 189/217 nt Homsap IGHJ6*02 F 130 67.74 42/62 nt Homsap IGHD1-26*01 F 3 8 8 17 8.8.17 [1.17.38.11] CVKEKYRRYSGIDYGVDVW in-frame + ctctggattcagcttctataactacatgatgcactgggtccgccgagttccagggaaggggctggagtgggtctctgttattagtagtgatgggagttacataaagtatgcggactccgtgaagggccggttcaccgtctccagagacaacgccaagagtacattgtatctgcaaatgagcagtctgagacccgaggactcggctgtatattactgtgtgaaagagaagtatcgacggtatagtgggatcgactacggtgtggacgtctggggccaaggggccacggtcacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc +4759 JY8QFUQ01BB2EM unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4760 JY8QFUQ01BTNQZ unproductive (see comment) Homsap IGHV4-59*03 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 X 8.7.X [1.17.38.11] CARGHFR**WLFQP#LDHW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 89 to 94 in the user submitted sequence), (do not cause frameshift); ctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttcgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4761 JY8QFUQ01AUZ6A No results +4762 JY8QFUQ01DG4PX No results +4763 JY8QFUQ01CURPS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 787 85.19 184/216 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [1.17.38.11] CVKDRDFLWGSYRLQLESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) tctggattcacctttagtagctatggcatgagttgggtccgccagtctccaaataagggactggagtgggtcgcaggcattagtgcaaatggtggcagtataaattatctggacgccgtgaagggccggtttatcatctctagagacaattccaagaacacgttgtatctgcaaatggacagcctgacagtcgaggacacggccgtttattactgtgtgaaagatcgtgattttctttgggggagctatcgtcttcaacttgaatcttggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4764 JY8QFUQ01CPBVE unproductive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD2-15*01 F 3 10 7 X 10.7.X [1.17.38.11] CATIVPSSVTALINDQGRFYFDH## out-of-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccagtgacggtgtcgtggaactcag +4765 JY8QFUQ01DR31P productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 856 88.13 193/219 nt Homsap IGHJ4*02 F (see comment) 132 75.0 36/48 nt Homsap IGHD6-13*01 F 1 8 8 10 8.8.10 [2.17.38.11] CANEVGYCSSRG in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gcctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccagggaaggggctggagtgggtctcaactattcgtgcccgtggtgataggacacactacgcggactccgtgaagggccgcttcaccatctctagagacaattcaaaggacaccctgtatttgcaaatgtacagcctgcgagtcgaggacacggccgtctattactgtgcgaacgaagtcgggtactgtagtagtcgggggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4766 JY8QFUQ01C74ZU unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 804 86.45 185/214 nt 85.98 184/214 nt 8 8 X 8.8.X [0.17.38.X] null + No rearrangement found in FR3-IMGT at codon 89 of V-REGION: 'A' (1 nucleotides at position 169 to 169 in the user submitted sequence), (cause frameshift); tggatatgactttagcagattttggatcgcctgggtgcgccagatgcccgggaaaggcctggagtggattggaatcatctatcctagtgactctgatacgagatacagtcccaccttccaaggccaggtcattatctcagccgacaagtccctcagtaccgcctacctAttttttcagcagtctgagggcctcggacaccgccatgtatttttgtgcgagacgtgattccgacttccgtatggacgtctggggccaggggtaccacggtcaccgtgtctccaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +4767 JY8QFUQ01BVQ9C productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD4-17*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDGDYENNYGMDVW in-frame + ctttggattcaccttcattagttatagcatgaactgggtccgccaggctccagggaaggggctggagtcaatttcatacattagtagtagcagtactaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggccatttattactgtgcgagagatggtgactacgaaaacaactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcttccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4768 JY8QFUQ01A27QT productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame - tctctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4769 JY8QFUQ01AI64L No results +4770 JY8QFUQ01B392Y productive Homsap IGHV4-4*07 F (see comment) 519 70.91 156/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-1*01 F 2 8 7 16 8.7.16 [3.17.38.11] CARERISSGGGPRHLEPW in-frame + Low V-REGION identity (70,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cactggaggtccggtcaacagtaatgactgctcttggacatggatccgagagtccgccgggaggggactggagtggattggccgtgtccatatgaatggccagaccgactacaatccatccttcggcagtcgtctcgccatgtccattgacacagtcaagaatgaattctcccttcgaatggtctctgtgaccgccgcagacacggccctatattactgtgcgcgagaacgtataagttccggtggcgggccgagacaccttgaaccctggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4771 JY8QFUQ01CHA0G No results +4772 JY8QFUQ01CJPSM productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 966 92.83 207/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaattacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4773 JY8QFUQ01B57SG unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 86 57.53 42/73 nt 8 X X 8.X.X [1.14.X.X] null - No rearrangement found cctctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4774 JY8QFUQ01BP38R unproductive (see comment) Homsap IGHV4-61*02 F 925 90.58 202/223 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 X 10.7.X [2.17.38.11] CAREK**SV#NWFDPW out-of-frame - stop codons tgtctctggtgactccatcaccagtggnaattattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggatcaccaactacaatccctccctcaagagtcgagtcaccatactattagacacgtccagcaaccggttctccctgaagctcagctctgtgaccgccgcagacacggccgtgtattactgtgcgagagaaaagtagtgatccgtcccaattggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4775 JY8QFUQ01B8UMI No results +4776 JY8QFUQ01DRE5J unproductive Homsap IGHV3-66*02 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [2.16.38.11] CAKLADTGEWSNRIFI#W out-of-frame - in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcagtagcagcttcatgacttgggtccgccagctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatctttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4777 JY8QFUQ01BM0OX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 8 8.8.8 [1.17.38.11] CAKRYSLDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttaagaactatgccttaaactgggtccgccaggctccagggaaggggctggagtgggtctccggaatcagtgctactggtgaaagcacacactacgcagactccgtaattggccggttcaccatctccagagacgattccaagaatacgttatatctgcaaatgaacagcctgagagccgaggacacggccgtatatttctgtgcgaaacgatattctcttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4778 JY8QFUQ01CT3VW productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDQRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcagcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4779 JY8QFUQ01C0YTX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4780 JY8QFUQ01A4M2O productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-22*01 F 2 7 8 17 7.8.17 [1.17.38.11] CARHSHSSGYSSLDALEIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 93 of V-REGION: 'C' (1 nucleotides at position 181 to 181 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) tctgcatatagttttccagttactggatcgcctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatcaatcccggtgactctgataccagatatagcccgtcctttcaaggccaggtcaccgtctcagccgacaggtccatcagtaccgcctacctgcagtggaaaaCgcctgagggcctcggacaccgccatgtattactgtgcgcgacactcccacagtagtggttattccagccttgacgctcttgagatctggggccaagggacaatggtcaccgtctcttctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4781 JY8QFUQ01CM4V1 No results +4782 JY8QFUQ01AW5OJ unknown (see comment) Homsap IGHV1-2*05 F (see comment) 415 74.19 115/155 nt 8 8 X 8.8.X [0.17.18.X] null + No rearrangement found Low V-REGION identity (74,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcaccaactactatcttcactgggtgcgacaggcccccggacaagggcttgagtggatgggacggatcaacccaaacagtggtggcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4783 JY8QFUQ01BUX4M unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CAREKGSGPPH#GMDVW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggccccccgcacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag +4784 JY8QFUQ01DFNUL unknown (see comment) Homsap IGHV3-23*02 F, or Homsap IGHV3-23*03 F (see comment) 263 70.54 79/112 nt 8 8 X 8.8.X [1.17.3.X] null + No rearrangement found Low V-REGION identity (70,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtcccaagatgggaacgtggtcgtcgcatgcctggtccaggg +4785 JY8QFUQ01COAZ0 productive (see comment) Homsap IGHV3-11*04 F 854 88.84 191/215 nt 87.91 189/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [1.16.38.11] CAKDELPWDTIEYYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggattcagtttcagtgactactacatgagttggatccgccaggctccagggaggggctggagtgggattcGatatattgatagcggtggtaccgccatgtactactcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4786 JY8QFUQ01BSYE7 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtg +4787 JY8QFUQ01CA1BC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [2.17.38.11] CANELGYCSGGG in-frame - gcctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtggggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4788 JY8QFUQ01DSFBK No results +4789 JY8QFUQ01C8BXD unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F (see comment) 271 57.99 127/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (57,99% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4790 JY8QFUQ01DA0XY No results +4791 JY8QFUQ01DM8ID unproductive (see comment) Homsap IGHV4-61*02 F 857 87.78 194/221 nt 87.33 193/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CAREGAWLHLQEV#FDYW out-of-frame + stop codons in CDR2-IMGT at codon 59 of V-REGION: 'ATT' (3 nucleotides at position 96 to 98 in the user submitted sequence), (do not cause frameshift); tctctgacgactccatcagcagtggcacttactactggagttggatccggcagcccgccgggaaggctccggagtggattggccgcttctatactATTactgggcgcaccaactacaatccctccctcgagagtcgagtcaccataacaagggacgtgtccaagaatcagttctccctgagactgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagagagggggcatggctacatctacaagaggtcttttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcaatgcctggtccagggcttc +4792 JY8QFUQ01A62TP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.16.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift) cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctgagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4793 JY8QFUQ01COJQ4 productive Homsap IGHV4-39*02 F (see comment) 758 82.81 183/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 10 7 22 10.7.22 [1.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame + Low V-REGION identity (82,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagaccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4794 JY8QFUQ01CCZ8Y No results +4795 JY8QFUQ01B0DYI No results +4796 JY8QFUQ01CCX0A productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-8*02 F 2 8 8 20 8.8.20 [1.17.38.11] CARDLWLCSGGECYHRGGFENW in-frame + ctctgggttcaccttcagtaactcctggatgcactgggtccgccaagctccagggaaggggccggagtgggtctcacgtattaatagtgatgggagtaatacaatctacgcggactccgtgaagggccgactcaccatctccagagacaacgccaaaaacacggtgtatctgcaattgaacagtctgagagccgaggacacggctgtgtactactgtgcaagagatctgtggctttgtagtggtggtgaatgctatcatcggggtggttttgagaactggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +4797 JY8QFUQ01BI479 No results +4798 JY8QFUQ01AKY3V unproductive Homsap IGHV1-58*01 F 876 90.19 193/214 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [0.17.38.11] CAASASYNGYDTDAFDI## out-of-frame - tggattcacctttgattcctctgctgtgcagtgggtgcggcaggctagtggacaccgccttgagtggatgggatggatcgtcgttgccaatggtaagacagactacgcacggaatctccagggaagagtcaccattgccagggacatgtccacaagtacagtctacatggagctgagcagcctgaaatccgaggacacggccgtatattactgtgcggccagtgcttcgtataatggctacgatactgatgcttttgatatctgggggcgaagggacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4799 JY8QFUQ01AW796 No results +4800 JY8QFUQ01CI7M9 No results +4801 JY8QFUQ01AZEJK unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 792 84.79 184/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4802 JY8QFUQ01A44QM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4803 JY8QFUQ01CA31J unknown (see comment) Homsap IGHV3-74*03 F 113 54.33 69/127 nt 8 8 X 8.8.X [1.17.7.X] null - No rearrangement found cctctggattcaccttcagtagctactggatgcactgggtccgccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4804 JY8QFUQ01APGRW productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CASGSGWTAEYW in-frame + ctctgaattcaccgttagcagtcattggatgaattgggtccgccaggctccagggaaggggctggaatgggtggccaacataaaacaagatgcaagtgagaaaaactatgtggactctgtgaagggccgattcaccatctcccgagacaacgccaagaattcactgtatctgcaaatgaacagcctgagactcgaggacacggctgtgtatttctgtgcgagtggcagtggctggacagctgaatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4805 JY8QFUQ01C16AG unproductive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSGFYSTGY# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagccaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccg +4806 JY8QFUQ01C5F9X unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 472 71.07 140/197 nt 8 7 X 8.7.X [1.17.32.X] null - No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01C5F9X ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (71,07% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4807 JY8QFUQ01CJB7R No results +4808 JY8QFUQ01B1QU5 No results +4809 JY8QFUQ01C80YW productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt 92.79 206/222 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD3-16*02 F 3 8 7 9 8.7.9 [4.16.38.11] CARGDPIFMIV in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaagggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggaccccattttcatgatagtgttaaggggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4810 JY8QFUQ01CSJRH unproductive Homsap IGHV3-66*02 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [2.16.38.11] CAKLADTGEWSNRIFI#W out-of-frame - in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaaggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatctttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4811 JY8QFUQ01BNVAV productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4812 JY8QFUQ01CYTK2 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 900 90.78 197/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + gtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4813 JY8QFUQ01DCD9M productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +4814 JY8QFUQ01ATZY0 No results +4815 JY8QFUQ01C6VCR productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame + ctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +4816 JY8QFUQ01BM12C productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 927 92.17 200/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) gtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4817 JY8QFUQ01A9IHK productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift); ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagaCtacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4818 JY8QFUQ01CR3K9 No results +4819 JY8QFUQ01B2YHD productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 937 92.24 202/219 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARDQSLGMPEAFDIW in-frame - gcctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4820 JY8QFUQ01DDB3S No results +4821 JY8QFUQ01AFBN6 productive (see comment) Homsap IGHV4-61*01 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtggtagCttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4822 JY8QFUQ01C4IRB No results +4823 JY8QFUQ01AX7OK productive Homsap IGHV3-7*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.38.11] CSRLLEEW in-frame + ctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccg +4824 JY8QFUQ01ATIZV productive Homsap IGHV3-66*02 F 840 88.32 189/214 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-8*01 F 3 8 7 11 8.7.11 [1.17.38.11] CASHLMVYALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccgtcagtggcaagtacatgagctgggtccgccaggctccagggcagggactggagtgggtctcagttatctatagtactggtagtacatactacgcagattccgtgaaagggcggttcaccatctccagagacagttccaacaacactctatatcttcaaatttacggcctgagagctgacgacacggctacttactactgtgcgagtcacttaatggtgtatgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4825 JY8QFUQ01BZ03R unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 103 52.99 71/134 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4826 JY8QFUQ01BRI6L productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4827 JY8QFUQ01CZ2QC No results +4828 JY8QFUQ01B2E25 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagcatgggaacgtggtccgtcgcctgcctggtccagggcttcttccccca +4829 JY8QFUQ01DHY7H No results +4830 JY8QFUQ01CT9XL No results +4831 JY8QFUQ01DWNCI No results +4832 JY8QFUQ01DQ9C2 productive Homsap IGHV3-66*02 F 948 93.93 201/214 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD6-13*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARDSPYSSGWSDGFDVW in-frame + ctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatatcagtggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaagaacacggtgtatcttcagatgaacagtctgagagctgaggacacggctgtgtattactgtgcgagagatagtccatatagcagcggctggtctgatggctttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4833 JY8QFUQ01CSXWT No results +4834 JY8QFUQ01AHOGJ No results +4835 JY8QFUQ01C2XOR No results +4836 JY8QFUQ01DTOOJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-25*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDLLGIAPAGHSLDHW in-frame + ctctggattcacctttggcaactatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagaggtgaccacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaggaacacactgtttctgcaaatgaatagcctgggagtcgaggacacgaccgtatattactgtgcgaaggatcttctagggattgcgccggcgggccattcccttgaccactggggccagggaaccctggtcgccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggcaacgtggtcatcgcctgcctggtccagggcttctccccca +4837 JY8QFUQ01A4KFE No results +4838 JY8QFUQ01CUFWM productive Homsap IGHV3-30*01 F 909 91.24 198/217 nt Homsap IGHJ4*03 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAREWAASHFDHW in-frame - cgctggattcaccttcagtggctttgctttgcactggctccgccaggctccagacaaggggctagagtgggtgggatttacatcatttgatgggagtaacagagactacgcagactccgtgaagggccgattcacgatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagacctgacgacacggctgtatattactgtgcgagagagtgggcagccagtcactttgaccactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4839 JY8QFUQ01C7UBY unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 387 76.3 103/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (76,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +4840 JY8QFUQ01C15WM No results +4841 JY8QFUQ01BQWX0 No results +4842 JY8QFUQ01CJDXX unknown (see comment) Homsap IGHV1-2*02 F 487 86.72 111/128 nt 8 8 X 8.8.X [0.17.9.X] null + No rearrangement found tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcaggg +4843 JY8QFUQ01ADHHB No results +4844 JY8QFUQ01CJBPC No results +4845 JY8QFUQ01CMKK2 unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 177 94.87 37/39 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcacctttggttattatggcatgagctgggt +4846 JY8QFUQ01AZMLB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD1-20*01 F 3 8 8 19 8.8.19 [1.17.38.11] CANASPLYNWNVFLLLRYGRL in-frame + Other possibilities: Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctcccccctgtataactggaacgtatttctactactacggtatggacgtctgggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca +4847 JY8QFUQ01CX0A5 unproductive (see comment) Homsap IGHV3-7*01 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAGDLTGVSVLL*Q*WFK#YW out-of-frame + stop codons tctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactggggtttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggccttcttcc +4848 JY8QFUQ01APCN7 No results +4849 JY8QFUQ01A3V0Z productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4850 JY8QFUQ01AQN7V productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4851 JY8QFUQ01A0UL2 No results +4852 JY8QFUQ01CSQX1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CVRDRSGQAVGYW in-frame - ctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4853 JY8QFUQ01BCLAX productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4854 JY8QFUQ01ARBLC productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagcaactGactggatgcactgggtccnccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4855 JY8QFUQ01AYSY2 No results +4856 JY8QFUQ01CN09R No results +4857 JY8QFUQ01C3SFA No results +4858 JY8QFUQ01CC1T7 No results +4859 JY8QFUQ01A62TI No results +4860 JY8QFUQ01BC3WS unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 450 67.28 146/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (67,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4861 JY8QFUQ01B5T7P No results +4862 JY8QFUQ01DRIS4 No results +4863 JY8QFUQ01BBTEQ No results +4864 JY8QFUQ01ARLS0 No results +4865 JY8QFUQ01B13L2 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 940 93.06 201/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'AG' (2 nucleotides at position 73 to 74 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggctgggatgggtcAGtctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4866 JY8QFUQ01DAW7G unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDV## out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggcccaagggacaatagtcaccgtctcctcagcctccacaagggccccatcggtcttccccctggcacctctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4867 JY8QFUQ01CRHX1 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 387 76.3 103/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (76,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +4868 JY8QFUQ01DNEWM productive (see comment) Homsap IGHV4-61*02 F 1001 95.02 210/221 nt 94.57 209/221 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD6-19*01 F 1 10 7 15 10.7.15 [1.17.38.11] CASTGYTSAPSEWMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggtggttccatcaccagtggtatttactactggagctggctccggcagcccgccgGggaagggactggagtggattgggcgtatctatacctttgggagcaccaactacaacccctccctcaacagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaatctgaactctgtgaccgccgctgacacggccgtgtattactgtgcgagtaccggatataccagtgccccaagcgagtggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4869 JY8QFUQ01DH2KW unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F (see comment) 612 75.58 164/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4870 JY8QFUQ01B1SS2 unknown (see comment) Homsap IGHV4-61*02 F 870 88.64 195/220 nt 88.18 194/220 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 9 7 X 9.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 27 in the user submitted sequence), (cause frameshift) tctctggtggctccgtcagtagtggttttactactggagctggacccggcagcccgccgggaagggactggagtggattgggcgtgtccatagcggtggtagttccgactacaacccctccctcacgggtcgagtcaccatcttagtggactcctccaagaatcagttctccctgaggctgacctctgtgacggccgcagacgcggccgtgtatttctgtgcgagagaagcgcctgcctggtccagggcttcttccccca +4871 JY8QFUQ01BONZZ productive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 947 94.34 200/212 nt 92.92 197/212 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 3 8 8 12 8.8.12 [0.16.38.11] CVRGNAVVAASDDW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'T' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) tggaggcaccttcagcagtcatgctatcagctgggtgcgacaggcccctgacaaggcttgagtggatgggcgggatcatAccctagctTttggtacaccaaactacgcacagaagttccagggcagagtcacgatgaccgcggacgaatccacgagcacagcctacatggagctgagcagcctcagatctgaagacacggccgtgtattattgtgtgagaggtaacgcggtggtagctgccagcgacgactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4872 JY8QFUQ01CMRCI unproductive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSGFTRR#YW out-of-frame - ctctggattcaggtttagtatctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacggcctgagagccgaggacacggctgtatattactgtgcgataagtagtggttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4873 JY8QFUQ01ANBSV No results +4874 JY8QFUQ01A3IDY unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 674 94.04 142/151 nt 8 8 X 8.8.X [1.17.16.X] null + No rearrangement found ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaat +4875 JY8QFUQ01CCM2O unproductive (see comment) Homsap IGHV3-7*03 F (see comment) 310 59.91 130/217 nt 59.45 129/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD2-8*02 F 2 8 8 X 8.8.X [1.17.38.11] V*EIVRVAGP#DYW out-of-frame - stop codons Low V-REGION identity (59,91% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggattcagttttagtgactttggatgcactgggtccgccaggcnccagggaaTggggctggagtgggtgggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4876 JY8QFUQ01BJO7P productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt 99.08 215/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.16.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccGtttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4877 JY8QFUQ01CC43S productive Homsap IGHV3-7*01 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [0.17.38.11] CAISSGYYSTGYW in-frame - tggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4878 JY8QFUQ01CVE9T No results +4879 JY8QFUQ01A8R3E productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD3-3*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKQTIFDYYYYGLDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); ctctggattcatgtttagtagctttcccatgggcCtgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4880 JY8QFUQ01BL72O productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [1.17.37.11] CAKDPFIAATGRPWYFEYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 156 in the user submitted sequence), (cause frameshift) tctggattcaccttcagcagctatggcatgcactggttccgccaggctccaggcaaggggctggagtgggtggcagctatctcatatgatggaattgacaaatattatgcagactccgtgaagggccgattcaccatctccagagacaatgccaaaacacgctgtatctgcaattgaacagcctgagaagtgaagacactgctgattactactgtgcgaaagacccatttatagccgcaactggccgcccctggtactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4881 JY8QFUQ01BFSFW unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 474 82.61 114/138 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (82,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc +4882 JY8QFUQ01CO1XL No results +4883 JY8QFUQ01BKWMA No results +4884 JY8QFUQ01BC3EN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 772 95.81 160/167 nt 8 8 X 8.8.X [1.17.21.X] null + No rearrangement found tctggattcacctttagtagttatgccatgaactgggtccgccaggccccagggaagggactggagtgggtctcagctattagtggtagtggtggtagcacaaactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactgta +4885 JY8QFUQ01DH4NU No results +4886 JY8QFUQ01DNZ96 productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcca +4887 JY8QFUQ01ANVJX productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.37.11] CVSDLAGQKGFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 167 in the user submitted sequence), (cause frameshift) tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4888 JY8QFUQ01DRPAB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4889 JY8QFUQ01DVLTJ No results +4890 JY8QFUQ01ATYER productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKLGVAATTWNFFDYW in-frame + tctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttcccccttggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4891 JY8QFUQ01CMRN2 No results +4892 JY8QFUQ01CQH36 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found ctctggattcatcttcagtagctactggatgcactggg +4893 JY8QFUQ01A8KQW productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + ctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4894 JY8QFUQ01DUI4B unknown (see comment) Homsap IGHV3-9*01 F (see comment) 414 65.44 142/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (65,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattacttggaacagtggtaggataggctatgcggactcttgtattattgtgcaaaatgatatggggtatacctggaagtacattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4895 JY8QFUQ01B9U8I productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 756 83.41 181/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatctagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +4896 JY8QFUQ01BUSG9 No results +4897 JY8QFUQ01BA3QB productive (see comment) Homsap IGHV3-7*01 F 890 90.7 195/215 nt 89.77 193/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 7 8 12 7.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) tctaaattcactttagtaactattggatgaattgggtccgccaggctccagCggaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4898 JY8QFUQ01CT0JJ No results +4899 JY8QFUQ01DBSNF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4900 JY8QFUQ01CVAIB No results +4901 JY8QFUQ01BDH7F No results +4902 JY8QFUQ01BBA5R productive (see comment) Homsap IGHV3-74*03 F (see comment) 684 79.72 173/217 nt 78.8 171/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAMRFCGGPECYPYLDNW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'AA' (2 nucleotides at position 98 to 99 in the user submitted sequence), (cause frameshift); ctctgggttcacattcagtaactactggatccactgggtccgccaagctccaggaaaAGggggctagagtggggtcgcactattaatgatgctgggaAAgcgtgccgacttcgcgacatttcgtgaagggccgattctccatctcccgagacaacgccaagaacacagtgtatctggaaatgactagtctgagagtcgacgacacggctgtctatttttgtgcaatgcgattttgtggtggtcctgagtgctacccttatcttgacaactggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4903 JY8QFUQ01DPNYP unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 176 58.82 80/136 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4904 JY8QFUQ01BESSR No results +4905 JY8QFUQ01C6JT1 No results +4906 JY8QFUQ01BBRHL unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDGGSYNRMDL## out-of-frame + gtctgggttcagtttcattgactatggcatacactgggtccgccaggctccaggcaaggggctggagtggatggcaattatatggtatgatgggaaaaataaatattatgaagagtccgtgaaggaccgattcaccgtctccagagacaattccaagaacacggtgtatttggaagtgaatagtctgagagtcgacgacacggctgtgtattactgtgcgagagacggtgggagctacaacaggatggacctttggggcccagggaaccctggtcaccgtctcgtcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +4907 JY8QFUQ01BT9J3 No results +4908 JY8QFUQ01DDYOO unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 106 55.77 58/104 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons ctctggattcaccttcagtcgttatagcatgaactgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4909 JY8QFUQ01CYXIH unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 84 51.06 72/141 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found cctctggattcacctttagtagttctgccatgaactggaggagtctggggaggcttggttcagcgggcgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4910 JY8QFUQ01B4GDP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4911 JY8QFUQ01CZW8C unknown (see comment) Homsap IGHV1-NL1*01 P 84 56.41 44/78 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccaga +4912 JY8QFUQ01B4U3Q unproductive Homsap IGHV3-13*01 F 903 91.59 196/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD4-11*01 ORF 1 8 7 X 8.7.X [1.17.38.11] CAREVTRLTCPL#YLYFDLW out-of-frame + ctctggaatcaccttcagtgactccgacatgcactgggtccgccaagctccaggagaaggtctggagtgggtcgcagctattggaactgctggtgatacatactatgcagactccgtgaagggccgattctccattaccagagagaatgccaagaactccttgtttcttcaaatgaacagcctgagagccggggacacggctgtttattattgtgcaagagaggtgactagacttacctgtcccctattacttatacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4913 JY8QFUQ01A5HCP unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 784 84.02 184/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4914 JY8QFUQ01CIZBF productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGRFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaagatttgactactggggccagggaaacctggtcaccgtctcctcagcctccacaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4915 JY8QFUQ01DP9ZJ unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 412 81.97 100/122 nt 81.15 99/122 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found Low V-REGION identity (81,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 67 of V-REGION: 'T' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); ctctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgtttctacttacaccattttctaTcgcagagtctgtta +4916 JY8QFUQ01A53VQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +4917 JY8QFUQ01A7GLV productive Homsap IGHV4-61*02 F 821 85.97 190/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 10 7 18 10.7.18 [1.17.38.11] CAREDYYGSGSYGRAWFDSW in-frame + tctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtgggggtgtcgactacaacccctccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagaggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtagtcatcgcctgcctggtccagggcttcttccc +4918 JY8QFUQ01AZ3JL productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [1.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) gttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgattttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4919 JY8QFUQ01B0NWJ No results +4920 JY8QFUQ01CU1G4 No results +4921 JY8QFUQ01CZEKC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacaacctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4922 JY8QFUQ01C4HOJ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 558 72.81 158/217 nt Homsap IGHJ1*01 F (see comment) 19 63.64 7/11 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (72,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity). The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctagattcatctttagtagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactatcagtggtagtggtgataacacatactacgcagactccgtgaagggccggttcaccatctccagagacaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +4923 JY8QFUQ01A2YCO productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 924 91.36 201/220 nt 90.91 200/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-7*01 F 3 8 8 13 8.8.13 [2.17.38.11] CATGAGNWNYIFNYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); ggcctctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgGgtttttatatatactacgcggattcagtgaagggccgagtcaccatctccagagacaacgccaagaattcgctatttctgcaaatgaacaacctgcgagccgaggacacggctgtctattactgtgcgacaggggccggaaactggaattacatttttaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4924 JY8QFUQ01DMUDG unknown (see comment) Homsap IGHV3-7*01 F 1036 96.8 212/219 nt 95.89 210/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); gcctctggattcagGgtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgTtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4925 JY8QFUQ01BKQYS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4926 JY8QFUQ01DBMQB productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 255 77.27 68/88 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.29.11] CVKDRKGSNWYYFENW in-frame - Low V-REGION identity (77,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggaattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4927 JY8QFUQ01CO5D5 productive Homsap IGHV3-11*01 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-3*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVREVTGVWDWFDSW in-frame + ctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgactcctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4928 JY8QFUQ01CTZFP productive Homsap IGHV3-64*02 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-9*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVRGRPMAGFHGILYDNW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttagtatcagtaattatggtattcactgggtccgccaggctccagggaggggactggaacttgtttcagctattaccaacaatgcgcatagtgtagtctatgtagactctgtgaagggcagattcatcatctccagagactattccaagaacacgttgtatcttcaaatgggcagactgagaccagaagacacggctgtgtactactgtgtcagagggcggcctatggctggctttcatggaatcctttatgacaactggggcctgggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +4929 JY8QFUQ01CF9OG productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 823 87.04 188/216 nt 86.57 187/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); gtctctggggactccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacactgggagtaCccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcaggaagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4930 JY8QFUQ01AZZ31 productive Homsap IGHV4-61*03 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 10 7 12 10.7.12 [1.17.38.11] CTRHPKSNVEGDSW in-frame + ccctggtggctccgtcagcagtggtagttatttctggagctggatccggcagcccccagggcaggggctggaatggatcggttatgtctataacaatgggaacaccaattacaacccttccctcaagagtcgagtcaccatttctatagacacgtccgagaatcacgtctccctgaagctggcctctgtgaccgctgcggacacggccgtgtactactgtacgaggcacccgaagtctaatgtagagggtgactcctggggccagggagccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct +4931 JY8QFUQ01A6TCD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4932 JY8QFUQ01BXO87 unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 133 63.64 49/77 nt 8 X X 8.X.X [1.16.X.X] null + No rearrangement found tctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +4933 JY8QFUQ01BSN89 No results +4934 JY8QFUQ01DG8S8 No results +4935 JY8QFUQ01AQXWF productive Homsap IGHV4-34*10 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame + gtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4936 JY8QFUQ01DNBC3 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [2.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); gcttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaTggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4937 JY8QFUQ01AJ891 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 78 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggcgtggagtgggtctctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4938 JY8QFUQ01BIQ13 No results +4939 JY8QFUQ01BIV2N No results +4940 JY8QFUQ01ADYD0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4941 JY8QFUQ01CC158 No results +4942 JY8QFUQ01DSAE2 No results +4943 JY8QFUQ01AZR16 unproductive (see comment) Homsap IGHV3-9*01 F 810 86.18 187/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD5-24*01 ORF 3 8 8 17 8.8.17 [1.17.38.11] CVKDRKAGGYNLLDAFDI* in-frame + stop codons ctctggattcaccttcgacgactatgtcatgcattgggtccggcaagttccagagaggggcctggagtgggtcgcaggcattaatggggaaagtaatagttttggctctgtggactctgtaaagggccgattcaccatctccagagacaaggccaagaataccctgtatttgcaaatgaatagcctgagagttgaggacacggccttgtattattgtgtgaaagatagaaaagctggtggctacaatctgttggatgcttttgatatctgaggccaagggacaatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4944 JY8QFUQ01CMDH5 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4945 JY8QFUQ01DXG6J unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 822 87.38 187/214 nt 86.92 186/214 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD1-1*01 F 2 8 7 X 8.7.X [1.17.38.11] CGRGDG#LDLW out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtctctggtcttaatttgaatggtgccacaggttatgcaaagtccgtgacgggccggtttaccatctccagagacaacgccaagaactccctgtatttggaaatggatagtctgagagtcgaagacacggccttctattattgtgggagaggggacgggggttggacctctggggccggggaatcctggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +4946 JY8QFUQ01DSVVP No results +4947 JY8QFUQ01AARG7 No results +4948 JY8QFUQ01DWNBV unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 942 92.27 203/220 nt 91.82 202/220 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); ggcctccggattcacctttagtagttactGggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4949 JY8QFUQ01CT6CG No results +4950 JY8QFUQ01BI4HP No results +4951 JY8QFUQ01AS0T2 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 639 93.79 136/145 nt 93.1 135/145 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 1 8 X 12 8.X.12 [1.8.31.11] CARRDVGLHAFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 72 nucleotides (from position 53 in the user submitted sequence), (do not cause frameshift) ttctggatccaattttaactacgactggatcggctgggtgcgccagatgcccggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgcttttgatctgtggggccaggggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4952 JY8QFUQ01C1M8M productive Homsap IGHV3-30*04 F, or Homsap IGHV3-30-3*03 F 864 88.94 193/217 nt Homsap IGHJ1*01 F (see comment) 179 82.69 43/52 nt Homsap IGHD2-21*02 F 2 8 8 8 8.8.8 [1.17.38.11] CSSGGDYPNW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcgacttcgatggccgtgctatgcactgggtccgccaggctccaggcaagaggctggagtgggtggcagttatctcatatgatggaaatgataaaaactacgcagactccgtgaggggccgattcaccatctccagagacaattctaaggacacgctgtttttgcaaatgaacagcctgagacatgaagacacgggtgaatatttctgttcttcaggaggtgactacccgaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccctcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +4953 JY8QFUQ01BRY9D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4954 JY8QFUQ01BJFVK productive (see comment) Homsap IGHV3-48*01 F (see comment) 759 84.11 180/214 nt 83.64 179/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4955 JY8QFUQ01C9D41 No results +4956 JY8QFUQ01ANCFE unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 99 59.72 43/72 nt 7 X X 7.X.X [X.17.X.X] null - No rearrangement found ttcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4957 JY8QFUQ01C4CSC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +4958 JY8QFUQ01DUQLJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4959 JY8QFUQ01AJXIE No results +4960 JY8QFUQ01AUT3T No results +4961 JY8QFUQ01CLHJ5 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 932 92.2 201/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + cctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgccctggtccagggcttcttccccca +4962 JY8QFUQ01CBVVZ No results +4963 JY8QFUQ01B0C4K productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4964 JY8QFUQ01A73JL No results +4965 JY8QFUQ01COSTG unknown (see comment) Homsap IGHV2-5*03 F 177 54.69 105/192 nt 10 7 X 10.7.X [9.17.26.X] null - No rearrangement found gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4966 JY8QFUQ01BXTHJ No results +4967 JY8QFUQ01DHXRX productive (see comment) Homsap IGHV3-48*01 F 1000 95.43 209/219 nt 94.98 208/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaAaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4968 JY8QFUQ01DDBVK No results +4969 JY8QFUQ01BJUHM productive Homsap IGHV3-11*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFDYW in-frame + ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcatacattagtgggagtgcgactaccatatcctacgcagactttgcgaagggccgattcaccatctccagggacaacgccaagaactcggtgtatctgcaaatgaacagcctgagagccgaggacacggccacgtattattgtgtgaggcgggtctggggatacagttatggttccgtttcgtattacttcgactactggggccagggaatcccggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4970 JY8QFUQ01AKQ8J No results +4971 JY8QFUQ01BMGFD productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + ctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4972 JY8QFUQ01CT8IW No results +4973 JY8QFUQ01CAZRX No results +4974 JY8QFUQ01CBUH5 No results +4975 JY8QFUQ01B8GEV unknown (see comment) Homsap IGHV3-7*02 F 108 59.26 48/81 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +4976 JY8QFUQ01DGP7M unproductive Homsap IGHV1-3*01 F 616 95.56 129/135 nt 94.81 128/135 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD4-23*01 ORF 2 8 X X 8.X.X [X.3.34.11] CTRGRGRELPSQPYCS#PW out-of-frame + in FR2-IMGT, from codon 42 of V-REGION: 78 nucleotides (from position 34 in the user submitted sequence), (do not cause frameshift) ggatataccttcactagttatgctatacattggaacttccagggcagagtcaccattaccagggacacatccgcgagcacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtatttctgtacgagaggccgggggagggaacttccctcccaaccctattgttcgaccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgtctggtccagggcttcttccccca +4977 JY8QFUQ01BI23D productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +4978 JY8QFUQ01CPTBR No results +4979 JY8QFUQ01BWF0D unknown (see comment) Homsap IGHV3-11*01 F (see comment) 756 83.41 181/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccctcagtgactacagtatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatacatcagccgaagtggaagtaatgtggaaactgcggactctgtgaggggccgattcaccgcctccagggacaccgccaataattcactgtttctgcggatgaatagcctgacagtcgaggacacggccctctattactgtgcgagagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +4980 JY8QFUQ01CXV7T productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +4981 JY8QFUQ01DJCTM productive (see comment) Homsap IGHV3-33*05 F (see comment) 752 83.03 181/218 nt 82.57 180/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); cgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatAttaatgaaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagagcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4982 JY8QFUQ01C68H5 unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt 10 9 X 10.9.X [1.17.38.X] null + No rearrangement found tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggtagatatga +4983 JY8QFUQ01B2LAD productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +4984 JY8QFUQ01CLYHH productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [0.17.38.11] CATSDVGARKFDYW in-frame + tggttacacctttaccagatatggtattagttgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcagcgtttccaatggtgacacaaactatgcacagaagctccagggcagagtcaccatgaccgcagacccatccacgagcacagcctacttggaactgaggagcctgacatctgacgacacggccgtatattactgtgcgacatctgacgttggagctcgaaagtttgactactggggccagggaacccaggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctccgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4985 JY8QFUQ01CNRRQ No results +4986 JY8QFUQ01C50X0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CARDVPGPNDNYFDYW in-frame + ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagggacgacgacacggctgtctatttctgtgcgagagatgtcccgggccccaatgacaactactttgactactggggccagggaaccctgcttaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4987 JY8QFUQ01CCF3T productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1053 98.62 214/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctgatcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +4988 JY8QFUQ01C8NJG No results +4989 JY8QFUQ01CI74R unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F (see comment) 360 63.77 132/207 nt 8 8 X 8.8.X [1.17.34.X] null - No rearrangement found Low V-REGION identity (63,77% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtcaaaaatattacgcagactcagtgaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4990 JY8QFUQ01BD3AU No results +4991 JY8QFUQ01DB4HA unproductive Homsap IGHV3-53*04 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 8 7 X 8.7.X [1.17.38.11] CARQTAPLG#FDLW out-of-frame - tctcggggttcaccgtccaaaacagcttcatgagttgggtccgccaggctccagggaagggcctagagtgggtctcagttgtttatagtggtggatccacatactacgcagactccgtgaagggccgtttcaccatcgccagacacagtcgcaacaacattctgtatcttcaaatgaacagcctgagacctgaggacacggctgtttacttctgtgcgagacagactgcccctttgggaactttgacttatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4992 JY8QFUQ01ACOEQ productive Homsap IGHV3-30*04 F, or Homsap IGHV3-30*10 F or Homsap IGHV3-30*17 F or Homsap IGHV3-30-3*03 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*02 F 2 8 8 16 8.8.16 [1.17.38.11] CARDLASFCGGDCPIDYW in-frame - cctctggatttcccttcagcaattacgctatgcactgggtccgccaggctctgggcaaggggctggagtgggtggcacttatttcgtatgatgggactaataaatactacatagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacagtgtatctgcaaatgaatagcctgagacttgaggacacggctgtgtatttctgtgcgagagatctggcatcattttgtggtggtgactgccccattgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4993 JY8QFUQ01AUKC7 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 123 50.95 107/210 nt 8 8 X 8.8.X [1.17.35.X] null - No rearrangement found cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4994 JY8QFUQ01AYEQ5 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 482 68.81 150/218 nt 68.35 149/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.16.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (68,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gcctctggattcacctttcgcagctatgccatgagctgggtccgccaggctccaggaaggggctagagtgggtctcatctatcagtggtagtggtgataaaacaaagtacgcagactccgtgaagggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4995 JY8QFUQ01BZBV8 unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 875 88.69 196/221 nt Homsap IGHJ3*02 F 169 82.0 41/50 nt Homsap IGHD6-6*01 F 1 10 7 X 10.7.X [1.17.38.11] CTNDRSMAVRATH#FHIW out-of-frame - stop codons tctctggtgactccattggtagcagtgcctactactggggctgggtccgccagccccccgggaaggggctggagtggattggaagtatctattatggtggcaacacctactacaacccgtccctcaggagtcgagtcagcatttccgcagacacgtccaagaaccagttctccctgcatctctactccgtgaccgccgcagacacggctctgtattactgtacgaatgaccgttcgatggccgttcgtgcaactcatgctttcatatctggggcctagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +4996 JY8QFUQ01DS9SP unknown (see comment) Homsap IGHV4-4*07 F, or Homsap IGHV4-61*02 F (see comment) 782 84.65 182/215 nt 83.72 180/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (84,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 37 of V-REGION: 'GAAGCT' (6 nucleotides at position 25 to 30 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift); tctctggaggctccatcagcagtgGAAGCTacttctggacctggatccggcagcccgccgggaaggatctggagtggattgggcgcttctacagtagtgacagtgtcgactacaaccccGtccctcaggggtcgagccaccatttcagcggacacgtccaagagccagttctcccttaatctgaagtctgcgaccgccgcagacacggccgtttattactgcgcgagagagaattactacggttcggggagttatgggcgggcctggtttgactactggggcccgggcaatccaggtcaccgtctctgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +4997 JY8QFUQ01DIHKE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 951 92.73 204/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - agcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +4998 JY8QFUQ01DGMSO unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaacccctgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +4999 JY8QFUQ01DGY73 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5000 JY8QFUQ01DJCTZ No results +5001 JY8QFUQ01AJG6I No results +5002 JY8QFUQ01ASMT6 productive Homsap IGHV4-39*02 F 951 92.73 204/220 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 10 7 12 10.7.12 [1.17.38.11] CASVTTVSMRMKYW in-frame + ctctggtggctccatcagcagtgatagttactactggggctggatccgccagtccccagggaaggggctggagtggattgggaatatctattatcgtgggagcacctattacaacccatccctcgagagtcggctcaccatgtcggtagacacgtccaggaacctcttctccctgaggctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagcgtgactacggtgtctatgaggatgaaatactggggccggggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5003 JY8QFUQ01BTWEZ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + tctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5004 JY8QFUQ01CBLDO No results +5005 JY8QFUQ01CUFUW productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 944 93.49 201/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtgtccatagcatGgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtgGgtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +5006 JY8QFUQ01C8MMO No results +5007 JY8QFUQ01B4V8L No results +5008 JY8QFUQ01ASEPQ productive Homsap IGHV3-66*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 12 8.7.12 [2.17.38.11] CARQTAPFGYFEDW in-frame - acctcggaatttctccgtcagtgacagtcacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtagtgcatattatgcagactccgtgaggggccgattcaccatcgccagagacaaatctaagaacgtgttgtatcttcaaatgaacagtctgagacctgaggacacggctgtgtactactgtgcgagacagactgccccttttgggtactttgaggactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5009 JY8QFUQ01AZHXC productive (see comment) Homsap IGHV3-7*01 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRDRFYDSSGYEFGELEDYSDHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctctggattcacatttagtaactactggatgagctgggtccgccaggCctccagggaaggggctggagtgggtggccaacataaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctgtgtgagagatcgattttatgatagtagtggttatgagtttggggaattggaggactactctgaccactggggccagggaacccaggtcaccgtctcctcagcttccaccaaggggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +5010 JY8QFUQ01C7E4L productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.16.38.11] CARDTLEVVSNMDDAFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5011 JY8QFUQ01BZ4LZ No results +5012 JY8QFUQ01DN5JL No results +5013 JY8QFUQ01CPO52 No results +5014 JY8QFUQ01AC3GH unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 489 82.98 117/141 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (82,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag +5015 JY8QFUQ01DSYWV unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 412 81.97 100/122 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found Low V-REGION identity (81,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgtttctacttacaccattttctacgcagagtctgtta +5016 JY8QFUQ01DGMHL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5017 JY8QFUQ01CMBZ5 unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*02 F or Homsap IGHV3-33*03 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F or Homsap IGHV3-64*01 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 115 54.2 71/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons gtctggattcaccttcagtagctacggcatgcactgggtccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +5018 JY8QFUQ01AXXAF No results +5019 JY8QFUQ01BYHVS No results +5020 JY8QFUQ01CDBFA No results +5021 JY8QFUQ01A4LYQ productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame - Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +5022 JY8QFUQ01BZ77K productive Homsap IGHV3-9*01 F (see comment) 783 84.79 184/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARVRCSGNTCGAFDLW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcatctttgatgattttgccatgcactgggtccggcatgctccagggaggggcctggagtgggtctcaagtatcaactggaatggtgacgtcaaagcctatgcggactccgtgaagggccgattcaccgtctccagggacaacgtccaaaactcactgtttttgcagatgattggcctgagagacgaggacacggccgtatattactgtgcgagagtccgctgtagtggtaatacctgcggggcttttgatttgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5023 JY8QFUQ01BRHVU productive (see comment) Homsap IGHV4-59*10 F, or Homsap IGHV4-61*02 F (see comment) 542 70.87 163/230 nt 70.0 161/230 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 7 15 8.7.15 [7.17.37.11] CARERDKSAAGGDFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (70,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 227 in the user submitted sequence), (cause frameshift) gtctccagtgacattattaatagcgaaggtttcggtcgtttctactggaactgggtccGggcagatcgacgggcaggggctggagtggatcgggcgtgtttatcgtgatgggatcacaaactacaatccatccttcgggacccggataagtttgtcgttagactcgtccaagaggcagttttccctgaagttacagtctgtgaccgccgcagacacggccgtatattttgtgcgagggagcgtgacaagtcggcggcgggcggcgactttgactcctggggccagggactcctggtcaccgtctcatctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5024 JY8QFUQ01ARLTJ No results +5025 JY8QFUQ01CAQM5 unproductive Homsap IGHV1-18*01 F 885 90.65 194/214 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [0.17.38.11] CARVIRTNWL#PW out-of-frame - tggttacacctttactacctatggcgtcacctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatgataatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacggccgtatattattgtgcgcgagtaattcgaaccaactggctcgaccctggggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5026 JY8QFUQ01BM7LQ productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-2*01 F 2 8 8 9 8.8.9 [1.16.38.11] CATRSRSPANW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcagttttagtacctattggatgagctgggtccgccaggctccagggaagggctggaatgggtggccaccataaacgaggatggaagtgacagaacctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaaaaattcattgtatctacaaatgaatagcctgagaaccgacgacacggctcgatattactgtgcgacgcgtagtagaagtccggcgaactggggccagggaagcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5027 JY8QFUQ01C8ERB No results +5028 JY8QFUQ01AN8M3 No results +5029 JY8QFUQ01AGRBK productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.16.38.11] CATDDSNGWDEVADYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagctcccattggatgagctgggtccgccagactccagggaagggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5030 JY8QFUQ01B8Q6L No results +5031 JY8QFUQ01ABL5K productive Homsap IGHV3-30*07 F, or Homsap IGHV3-30*16 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYYFDSW in-frame + ctctggattcaccttcagtatttattctatgcattgggtccgccaggccccaggcaaggggctagagtgggtggcagttatatcacatgatggaactaataaatattactcagactccgtgaagggccgattcaccatctccagagacaattccaagagcgcgctgtatctgcagctgaacgtcctgagcgccgaggacacggctgtctatttctgtgcgagagattccgtacctcgggcgtcagaggctgcctactactttgactcttggggccagggaaccctggtcaccgtctccccagcatccccgaccagcccaaggtcttcccgctgacgcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5032 JY8QFUQ01DVS60 No results +5033 JY8QFUQ01ACBC6 No results +5034 JY8QFUQ01BVBOA productive Homsap IGHV3-66*02 F 813 86.92 186/214 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-10*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARVRFGPSYLDVFDIW in-frame + ctctggattcaccgtcaatagttatcacatgagttgggttcgccaggctccagggaaggggccggagtgggtctcaattatttatccggatggtgacgcattctacgcagactccgtgaagggccgattcaccttctccagagacatttccaagaacacggtgtatctccaaattaacagagtgacaactgaggacacggctatgtactactgtgcgagagtccggttcgggccaagttatctggatgtctttgacatctggggccaagggacattggccaccgtctcttcagcatccccggaccagcccaaggtcttcccgctgagcctctgcagcaccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +5035 JY8QFUQ01BWW54 unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 134 63.29 50/79 nt 8 X X 8.X.X [1.17.X.X] null + No rearrangement found ctctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5036 JY8QFUQ01A0Y9N No results +5037 JY8QFUQ01AZG3J productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +5038 JY8QFUQ01DS4YW unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 491 84.56 115/136 nt 83.09 113/136 nt 8 8 X 8.8.X [1.16.11.X] null + No rearrangement found Low V-REGION identity (84,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc +5039 JY8QFUQ01BOVSG unproductive (see comment) Homsap IGHV3-7*01 F 881 90.23 194/215 nt 89.3 192/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) tctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgGaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctgggccaaggaccacggtcaccgtctcctcagcatcccggaccagcccaaggtcttccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5040 JY8QFUQ01A5AND productive Homsap IGHV3-30*15 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARNELPWDTREYYFDYW in-frame + ctccggattcacctttagtaaatattccatgaactgggtccgccaggctccaggcaaggggctcgagtgggtggcacttatatcatacgatggaagtagaaaaatctacgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5041 JY8QFUQ01BZNR8 No results +5042 JY8QFUQ01DOOBW productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD4-17*01 F 2 8 7 18 8.7.18 [1.17.38.11] CASVVTINDNGDYTWAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcaataattacttctggacctggatccgccagTcccccagggaaggggccggagtggattggggaaatcaatcatagtggtagcaccaactacaatccgtccctcaagagtcgagtcaccatctcaatagacacgtccaagatccagttctccctgcagctgagctctgtgaccgccgcggacacggctgtctattactgtgccagtgtagtgaccattaatgacaacggtgactacacgtgggcttttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +5043 JY8QFUQ01CCKWB productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5044 JY8QFUQ01AUYN2 No results +5045 JY8QFUQ01DJ448 No results +5046 JY8QFUQ01AJHY7 No results +5047 JY8QFUQ01CLTWE unknown (see comment) Homsap IGHV3-7*02 F 103 58.75 47/80 nt 8 1 X 8.1.X [0.17.X.X] null + No rearrangement found ctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +5048 JY8QFUQ01DFDPJ No results +5049 JY8QFUQ01A97QT productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 750 83.64 179/214 nt 83.18 178/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc +5050 JY8QFUQ01A09MY No results +5051 JY8QFUQ01DIMK5 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found ctctggattcatcttcagtagctactggatgcactggg +5052 JY8QFUQ01AP6HU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKLENSSGNEDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctgaattaacgtttgatatatatgccatgacttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactggtagtggtgataatgcctactacgcagacttcgtgaagggccgattcgccatctccagagacaattccaagaacatgttgtatttgcaaatgaacaacctgcgaggcgaggacacggccgtttattactgtgcgaaactggaaaatagcagtgggaatgaagactcctggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5053 JY8QFUQ01DHFHJ No results +5054 JY8QFUQ01DFNDX productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.14 211/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctaCctggagctGggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctacctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5055 JY8QFUQ01B2EJ0 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame + ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag +5056 JY8QFUQ01AFMEW No results +5057 JY8QFUQ01CM2M0 No results +5058 JY8QFUQ01DEH2Y productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD2-8*02 F 2 8 8 18 8.8.18 [1.17.38.11] CARDLDYSNGGVSYDALDVW in-frame + ctctggatccacctttagtaattattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacatagagaaagacggaagtgtggagaactatttggactctgtgaagggccgattcaccatctccagagacaacgccaggaactcactgtatctgcaaatgaacggcctgagagccgaagatacggctgtctattactgtgcgagagatttggattatagtaatggtggtgtctcgtacgatgctcttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5059 JY8QFUQ01DAH5C No results +5060 JY8QFUQ01CFD78 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [2.17.38.11] CAKVSGNSRTYWYLDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); ggttctggatacaactttcccagatattggatcgcctCgggtgcgccagattcccgggagaggcctggagtgggtggggatgatctatcctggtgactctgagaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacgcgtccatgaacaccgcctacctgcagtggagcagcctgaaggcctccgacaccgccatatacttctgtgcgaaggtctctggtaactctcgaacctactggtacctcgatatctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5061 JY8QFUQ01BHQK6 productive Homsap IGHV3-9*01 F (see comment) 793 84.93 186/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [2.17.38.11] CGRIAKPGLGALDLW in-frame - Low V-REGION identity (84,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ggcgttggattcacttttaatgaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctggggccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5062 JY8QFUQ01CRABK productive Homsap IGHV3-21*04 F (see comment) 626 76.61 167/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVRLFTSDGVRGDYW in-frame - Low V-REGION identity (76,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctccggttcatcttcagtcacttcagcatgaactgggtccgccaggctccaggaaagggcctggagtggatcgccgacatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcgacgatacggccacctattattgtgtgaggctcttcaccagcgatggagtgagaggcgactactggggccagggcgcccgggttctcgtctccgcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5063 JY8QFUQ01DGGN2 No results +5064 JY8QFUQ01DVMYE productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 955 93.15 204/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [2.17.38.11] CARGGLEPVDYW in-frame - ccctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaattacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5065 JY8QFUQ01A2N5A No results +5066 JY8QFUQ01A77BB unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 858 89.25 191/214 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 X 8.7.X [1.17.38.11] CARPHI*QRP#DAFDTW out-of-frame + stop codons Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggccccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccc +5067 JY8QFUQ01DAEUC No results +5068 JY8QFUQ01BGJYF productive Homsap IGHV3-30*01 F 977 94.5 206/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcca +5069 JY8QFUQ01BVQBH No results +5070 JY8QFUQ01C74JE No results +5071 JY8QFUQ01ANKSU productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 926 92.56 199/215 nt 91.63 197/215 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ccggattcagtttcagtacttaGtaacatgaattgggtccgccaggctccagggaaTggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5072 JY8QFUQ01AFDCM productive Homsap IGHV4-39*03 F 920 90.91 200/220 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-14*01 ORF 2 10 7 12 10.7.12 [1.17.38.11] CTREGPYYYGMDVW in-frame + tctctggtgactccatcagtaatactgattactactgggtctggatccgccagaccccagggaagggactggagtggattgggagtatcgatttcagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccatagacacgtccgagaaccggttctccctgaggttgacctctatgaccgccgcagacacggccgtctattactgtacgagagagggaccctactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +5073 JY8QFUQ01DLSNF productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame - tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5074 JY8QFUQ01CYNKU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + tctggattcaccttcagtacatactggatgcactgggtccaccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5075 JY8QFUQ01C6DDZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKDMGGDYYIFHYW in-frame + ttctggattctcctttagcaactatgccctggcctgggtccgccaggctccagggaaggggctggagtgggtctcaattgttagtggaagtggtactggcacaggccacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggatatgggtggcgactattacatctttcactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5076 JY8QFUQ01DJO6B productive Homsap IGHV3-30*04 F, or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVRGSSGRFDSW in-frame + ctctggattcaccttcagaaaatatgctatgcactgggtccgccaggctccaggcaaggggctggaatgggtggcgattatatcctatgatggaagaagtccatactacgcagactccgtgaggggccgattcaccatctccagagacaattccaggagtactctggatctgcagatgaacagcctgagacctgaggacacggctgtatattcctgtgtgagaggaagcagtggccgctttgactcctggggcccgggaacgctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc +5077 JY8QFUQ01C6DIT productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1047 99.07 212/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + ctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5078 JY8QFUQ01BUZ3T No results +5079 JY8QFUQ01AR2LH No results +5080 JY8QFUQ01DP8YH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtGgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5081 JY8QFUQ01BUXBZ No results +5082 JY8QFUQ01DU88I unknown (see comment) Homsap IGHV5-51*05 F 149 56.62 77/136 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found gttctgcatatagtttttccagttactggatcgcctgggtgcgccagatgcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5083 JY8QFUQ01CQ0LJ productive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 876 90.19 193/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [0.17.38.11] CARGRRDNTGYYWYYFESW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'G' (1 nucleotides at position 138 to 138 in the user submitted sequence), (cause frameshift); cagagactcctttatcagctatgGttttcagctgggtgcgacaggcccctggacaagggcttgagtggatgggagggatcgtcccgatgtctgccacagcaaattatgcacagaagttccagggcagagtcacaattGaccgcggacggatccacgagcacagcctacatggaattgagcagcctgagatctgaggacacggccatgtattactgtgcgagagggagacgggataatactggttattattggtactactttgaatcctggggccagggaaccctgatcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +5084 JY8QFUQ01C8GBT No results +5085 JY8QFUQ01CPIJA productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5086 JY8QFUQ01B37M4 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.16.38.11] CVSDLAGQKGSW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaagggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5087 JY8QFUQ01AXJEC unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F (see comment) 204 78.79 52/66 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found Low V-REGION identity (78,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagtttcagtacctatgcaatgcactgggtccgccaggctccagggcttcttccccc +5088 JY8QFUQ01CD1G0 No results +5089 JY8QFUQ01BTQNU No results +5090 JY8QFUQ01AZ9YP No results +5091 JY8QFUQ01AKGXY unproductive Homsap IGHV3-72*01 F 1083 98.65 220/223 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYD#PG out-of-frame + ctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc +5092 JY8QFUQ01A26C2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5093 JY8QFUQ01A2UDI No results +5094 JY8QFUQ01CB6I7 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 687 80.37 172/214 nt 79.91 171/214 nt Homsap IGHJ4*03 F (see comment) 114 70.83 34/48 nt Homsap IGHD1-7*01 F 1 8 7 X 8.7.X [1.17.38.11] CARLDGHFDL## out-of-frame + Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 77 of V-REGION: 'GAA' (3 nucleotides at position 131 to 133 in the user submitted sequence), (do not cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcgggcttGAAtcgatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctgggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +5095 JY8QFUQ01CS6PE productive (see comment) Homsap IGHV3-7*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggatttacttttaacaactattggatgacctGgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5096 JY8QFUQ01BBZNR No results +5097 JY8QFUQ01BC565 No results +5098 JY8QFUQ01BADKE No results +5099 JY8QFUQ01APK97 productive Homsap IGHV3-21*04 F 963 94.01 204/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*03 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +5100 JY8QFUQ01CTUEZ productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame + tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccgagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5101 JY8QFUQ01APG97 No results +5102 JY8QFUQ01CMK2H productive Homsap IGHV3-48*02 F 971 94.88 204/215 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 1 8 8 19 8.8.19 [0.17.38.11] CARPAGEGDPFFHYYSGLDVW in-frame - ctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgtttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5103 JY8QFUQ01CZGGI No results +5104 JY8QFUQ01DIATI productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5105 JY8QFUQ01DDI7L No results +5106 JY8QFUQ01BS2WD productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggGggctggtgtgggtctcacgtactaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattattgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +5107 JY8QFUQ01A6LFT productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [0.17.38.11] CATSDVGARKFDYW in-frame + tggttacacctttaccagatatggtattagttgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcagcgtttccaatggtgacacaaactatgcacagaagctccagggcagagtcaccatgaccgcagacccatccacgagcacagcctacttggaactgaggagcctgacatctgacgacacggccgtatattactgtgcgacatctgacgttggagctcgaaagtttgactactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5108 JY8QFUQ01CIW5U No results +5109 JY8QFUQ01AN1WA No results +5110 JY8QFUQ01C8HAX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGVRGVGAYYIYYF#DLW out-of-frame + ctctggattcacctttggcctctatgccatgaactgggtccgccagactccagggaaggggctggagtggctcgcaactattagtggtagtggaagtagatcattttacgcagactccctgaagggccggttcaccatctccagagacaattccaagggcacggtatacctggaaatgaccaccctgagagccgaggacacggccgtatattactgtgcgagagatggggtccgtggcgttggtgcttactacatctactattttcgacttatggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5111 JY8QFUQ01DTGQA productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 714 81.78 175/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Low V-REGION identity (81,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcaccatcactcactactccatggcctgggtccgccaggctccggggaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcgcctcatcatctccagagacgaatccaagagtgagctgtatcttcggatgacgaaagtgaaagccgaagacgcggccgtatattactgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaaagatgggaacgtggtcgtcgcatgcctggtccagggcttct +5112 JY8QFUQ01A6WP2 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 854 90.78 187/206 nt 90.29 186/206 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 9 nucleotides (from position 15 in the user submitted sequence), (do not cause frameshift) tctctggtgactctcacttctggagctggatccggcagcccccagggaagggcccggagtggattggttatgtctataacagtgggaccaccaactacaacccctccctcaggagtcgagtcaccatttctatcgacacgtccaagaagcagatctccctgaagttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5113 JY8QFUQ01BGM6K No results +5114 JY8QFUQ01CWSIN No results +5115 JY8QFUQ01AHJ9B productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5116 JY8QFUQ01BANEM No results +5117 JY8QFUQ01DPKNZ productive (see comment) Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 393 91.49 86/94 nt 90.43 85/94 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD5-18*01 F 3 X X 15 X.X.15 [X.X.31.11] CARSDEEYSYGDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'ACTAT' (5 nucleotides at position 21 to 25 in the user submitted sequence), (cause frameshift); gtctggattcaccttcagtaACTATgagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatcggacgaggaatacagctatggggatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +5118 JY8QFUQ01BQOPQ productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 1035 97.7 212/217 nt 97.24 211/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.16.38.11] CVSSPYFYDSNGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaagggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaacgatggaacgtggtcgtcgcatgcctggtccagggcttctt +5119 JY8QFUQ01ASOJD No results +5120 JY8QFUQ01DRI4G No results +5121 JY8QFUQ01CKARI productive (see comment) Homsap IGHV3-30*13 F (see comment) 228 77.22 61/79 nt 75.95 60/79 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 1 X X 14 X.X.14 [X.X.26.11] CAKDLFQVSTTYFDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (77,22% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 87 of V-REGION: 12 nucleotides (from position 38 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcagtgactatcacatgtactggatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5122 JY8QFUQ01CNHKN No results +5123 JY8QFUQ01BPO99 No results +5124 JY8QFUQ01BOPDW No results +5125 JY8QFUQ01CBTGU No results +5126 JY8QFUQ01CXUGN unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +5127 JY8QFUQ01A4D0Z productive (see comment) Homsap IGHV1-3*01 F 966 94.86 203/214 nt 94.39 202/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARWNNDLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcagtacctatactatgaattgggtgcgccaggGcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5128 JY8QFUQ01DFW5N productive Homsap IGHV4-34*10 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame + tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5129 JY8QFUQ01C7X1A unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 927 92.17 200/217 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARGMATAES## out-of-frame + ctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccagggggaccctggtcaccgtctcctcagcatccccgaccagcccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5130 JY8QFUQ01AS7JA productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); gtctggattcacAgtttagaagctaGttccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5131 JY8QFUQ01CUCMD productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 828 87.1 189/217 nt 85.71 186/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); tgtctctggggactccattagtggttactattggacgtggatccggcagAgccccagggaagggactggagtggattggaaatgtccattacacCtgggagtaCccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccatggcttcttccccca +5132 JY8QFUQ01CIAB5 No results +5133 JY8QFUQ01AT3R5 unproductive Homsap IGHV3-33*03 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 X 8.7.X [1.17.38.11] CARDGEQWLVWTL#DVW out-of-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 99 in the user submitted sequence), (cause frameshift) tctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5134 JY8QFUQ01C7PBB No results +5135 JY8QFUQ01ABIUK productive (see comment) Homsap IGHV3-13*01 F 966 94.86 203/214 nt 94.39 202/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.37.11] CARGSSKAYNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 192 in the user submitted sequence), (cause frameshift) cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccgggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5136 JY8QFUQ01A0WZB productive Homsap IGHV3-66*02 F (see comment) 759 84.11 180/214 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-21*01 F 3 8 7 11 8.7.11 [1.17.38.11] CARHLMVYALDVW in-frame + Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaggggctggagtgggtctcagtcttatttagtactggcactgcatactacgcagactccgtgaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5137 JY8QFUQ01CO6CF unproductive (see comment) Homsap IGHV3-7*01 F 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [2.16.38.11] CATSPLR*LLGRT#YW out-of-frame - stop codons in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) gcctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctcccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5138 JY8QFUQ01BZQY5 productive Homsap IGHV3-11*06 F, or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F (see comment) 388 78.29 101/129 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-8*01 F 2 X 5 17 X.5.17 [X.X.38.11] CVRDVSLYSNDGYDAFDIW in-frame + Low V-REGION identity (78,29% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcattttagtaacttttggatgagttggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagagacgtctccctttatagtaatgatggatatgatgcttttgatatttggggccaggggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccccca +5139 JY8QFUQ01DDAQ6 productive Homsap IGHV3-11*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtgcgtggaactcag +5140 JY8QFUQ01DGCAX unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 674 94.04 142/151 nt 93.38 141/151 nt 8 8 X 8.8.X [1.17.15.X] null - No rearrangement found in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 125 in the user submitted sequence), (cause frameshift) ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaaggccgattcaccatctccagagacaatg +5141 JY8QFUQ01AT892 No results +5142 JY8QFUQ01BQGYG unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 910 90.87 199/219 nt Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD6-6*01 F 2 8 8 X 8.8.X [2.17.38.11] CVRSEYSSSNWFDP# out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gcctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgaccctggggccagggaccctggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5143 JY8QFUQ01C4PMS No results +5144 JY8QFUQ01DEWTJ unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt 84.79 184/217 nt Homsap IGHJ4*03 F 69 60.42 29/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDSDSSGYARYDSMDV## out-of-frame + in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgGggtctcacacgtcaatCgggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaatgggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactca +5145 JY8QFUQ01AMARQ productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 948 93.93 201/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.37.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'AG' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 120 in the user submitted sequence), (cause frameshift) ctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtAGgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgagggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5146 JY8QFUQ01C8QWZ productive Homsap IGHV1-3*01 F 966 94.86 203/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARWNNDLDYW in-frame + tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggctccagggcttcttccccc +5147 JY8QFUQ01AM7DF No results +5148 JY8QFUQ01AH10K productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccAaagctccggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5149 JY8QFUQ01BA59S unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1061 99.53 214/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons tctctgatggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5150 JY8QFUQ01AIWSZ unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 508 70.83 153/216 nt Homsap IGHJ1*01 F, or Homsap IGHJ5*02 F (see comment) 17 71.43 5/7 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (70,83% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctgggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +5151 JY8QFUQ01ALLUG No results +5152 JY8QFUQ01APGUQ No results +5153 JY8QFUQ01BLBYX productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame - tgttcggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgattttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5154 JY8QFUQ01DSN0F unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5155 JY8QFUQ01AWLZU No results +5156 JY8QFUQ01CFKI3 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacaGccccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgc +5157 JY8QFUQ01A3G7V unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 788 92.86 169/182 nt 92.31 168/182 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD3-16*02 F 1 6 8 X 6.8.X [1.6.38.11] CARDGPPLV**FSWGSYRHPT#WFDPW out-of-frame + stop codons in CDR1-IMGT, from codon 37 of V-REGION: 35 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtggttaacctggagtgggtctcatccattactagtaatactacttacatatacaacacagactcagtggagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagaaccgaggacacggctgtgtattaatgtgcgagagatggacctccgctggtatgatgattttcttgggggagttatcgtcatcctacgtctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +5158 JY8QFUQ01BKSL7 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 703 80.37 176/219 nt 79.0 173/219 nt 8 8 X 8.8.X [2.16.37.X] null - No rearrangement found Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 126 in the user submitted sequence), (cause frameshift) cagcctctggatccagtttcagtggAttttggcgtgaactgggtccgccaggctccagggaagggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgagggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5159 JY8QFUQ01B2OZ4 No results +5160 JY8QFUQ01C1NY7 No results +5161 JY8QFUQ01DI6EW productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 13 8.8.13 [1.17.38.11] CARGGGGKSIPLDNW in-frame + gtctggcttcacgttcagtagttatggcatgcaatgggtccgccaggctccaggcaaggggctggagtgggtggcagttatttggtatgatggaagtaataaatattatgcagactccgtgaagggccgattcgacatctccagagacaattccaagaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatgtaccattgtgcgagaggcggcggtggtaagtccattccacttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5162 JY8QFUQ01AE4ZJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 130 67.74 42/62 nt Homsap IGHD1-1*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKMKGLYYYDYGMDVW in-frame + ttctggactcaccttcagcagctttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagctatgagtggtagtggtagtagcacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagtgccgacgacacggccgcatattactgtgcgaaaatgaaaggactttactactacgactacggtatggacgtctggggccaaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +5163 JY8QFUQ01DNO4C No results +5164 JY8QFUQ01CSZL8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctcaggactcatgtttagcagctatgccatgacctgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +5165 JY8QFUQ01DIK46 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5166 JY8QFUQ01C4LUX No results +5167 JY8QFUQ01B6F5W productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame + ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5168 JY8QFUQ01BP9GL productive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [1.17.38.11] CARVIPGRGNYAFDVW in-frame + ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5169 JY8QFUQ01BMSTT productive (see comment) Homsap IGHV3-9*01 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); tctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatcCtttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5170 JY8QFUQ01C7VF4 productive (see comment) Homsap IGHV3-30*01 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYHFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); ctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttaCtttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5171 JY8QFUQ01CLEUK unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F (see comment) 360 63.77 132/207 nt 8 8 X 8.8.X [1.17.34.X] null - No rearrangement found Low V-REGION identity (63,77% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtcaaaaatattacgcagactcagtgaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5172 JY8QFUQ01CFBGF No results +5173 JY8QFUQ01AF4W2 No results +5174 JY8QFUQ01A882H productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 810 86.18 187/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 3 8 8 16 8.8.16 [1.17.38.11] CARDLPAMGKYYYGMDVW in-frame + ctctggatttatgctcaggacttatgacatgaattgggtccgccaggctccagggaaggggctggagtgggtcgcatccattagtagaaatacagattacacatattacgcagactcagtgaggggccgattcaccatctccagagacaacgccgaaaactcactatttttgcaaatgagcagtctgagagccgaggacacggctctctatttctgtgcgagagatttgccggctatgggaaagtactactatggcatggacgtctggggccaagggaccacggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5175 JY8QFUQ01BK44J unproductive (see comment) Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CVKDMVAGQGLLSR#FDHW out-of-frame + stop codons Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggttttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +5176 JY8QFUQ01AEWPW productive Homsap IGHV3-7*01 F 882 89.4 194/217 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctcaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5177 JY8QFUQ01CMEYE No results +5178 JY8QFUQ01BN31F productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccctca +5179 JY8QFUQ01AT7IJ No results +5180 JY8QFUQ01ARI0Z productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +5181 JY8QFUQ01C61KK productive Homsap IGHV3-11*01 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARARGVIPSFW in-frame - cctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaagggggctgagtgggtttcatacattagtagtagtggtggttccgtatactacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagacctcactgtatctgcaaatgaacaatctgagagccgaggacacggccgtgtattactgtgcgagagcccggggagtaatcccttcattctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +5182 JY8QFUQ01BN5MV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cgtctggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +5183 JY8QFUQ01BCXG0 No results +5184 JY8QFUQ01DWPP9 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1019 95.93 212/221 nt 95.48 211/221 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD6-6*01 F 3 8 8 X 8.8.X [2.17.38.11] CVRSEYSSSNWF#PW out-of-frame - in FR3-IMGT at codon 77 of V-REGION: 'G' (1 nucleotides at position 138 to 138 in the user submitted sequence), (cause frameshift); cagcctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcGaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgaccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5185 JY8QFUQ01B7KB8 No results +5186 JY8QFUQ01DD8NN productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggCcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttcccccatggcacccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactcag +5187 JY8QFUQ01AE0ZW productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5188 JY8QFUQ01B3WH5 No results +5189 JY8QFUQ01AHVRK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5190 JY8QFUQ01B0UUI unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 881 90.23 194/215 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 21 8.8.21 [0.17.38.11] CVRVGAPYYDFWSGYQTNWFDPW in-frame - stop codons tctgattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgcaagtactacttccatacattatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggcgccatattacgatttctggagtggctatcagactaactggttcgacccctggggccagggaactctggtcaccgttacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5191 JY8QFUQ01CQYHB unknown (see comment) Homsap IGHV4-59*02 F 899 90.7 195/215 nt 89.77 193/215 nt 8 7 X 8.7.X [1.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 36 of V-REGION: 'GAT' (3 nucleotides at position 21 to 23 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'TACGATCCCTCC' (12 nucleotides at position 108 to 119 in the user submitted sequence), (do not cause frameshift); tctctggtggctccgtcagaGATttttattactggagttgggtccggcagcccccagggaagggactggagtggcttggatatctctattacagagggagcaccaagTACGATCCCTCCtataatccctccctcgagagtcgagtcaccatttcagttgacccgtccaagaaccagttctccctgaagctaaactctgtgaccgctgcggacacggccgtgtattactgcgcgagagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5192 JY8QFUQ01DHH0D productive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame + ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5193 JY8QFUQ01CXD60 unknown (see comment) Homsap IGHV3-74*03 F 160 54.05 100/185 nt 8 8 X 8.8.X [1.17.27.X] null - No rearrangement found ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtcaccgtctcctcagcatccccgaccagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5194 JY8QFUQ01CIAYO No results +5195 JY8QFUQ01ACBYC No results +5196 JY8QFUQ01DVGYW No results +5197 JY8QFUQ01C6Z6P unknown (see comment) Homsap IGHV1-2*01 F, or Homsap IGHV1-2*02 F or Homsap IGHV1-2*04 F or Homsap IGHV1-2*05 F 142 82.93 34/41 nt 8 X X 8.X.X [0.5.X.X] null + No rearrangement found tggatacacattcaccggccacttcgtccactggctgcgac +5198 JY8QFUQ01AJTH3 productive Homsap IGHV4-39*02 F 951 92.73 204/220 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 10 7 12 10.7.12 [1.17.38.11] CASVTTVSMRMKYW in-frame + ctctggtggctccatcagcagtgatagttactactggggctggatccgccagtccccagggaaggggctggagtggattgggaatatctattatcgtgggagcacctattacaacccatccctcgagagtcggctcaccatgtcggtagacacgtccaggaacctcttctccctgaggctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagcgtgactacggtgtctatgaggatgaaatactggggccggggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5199 JY8QFUQ01CLIPB No results +5200 JY8QFUQ01A2Y4W No results +5201 JY8QFUQ01B8PVL No results +5202 JY8QFUQ01DLE29 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5203 JY8QFUQ01C9MW1 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 862 89.67 191/213 nt 89.2 190/213 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 7 8 10 7.8.10 [0.17.38.11] CVSDLAGQKGFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) tggattcacttcagtaacgcctggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5204 JY8QFUQ01DT69E unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 193 93.18 41/44 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found tctggattcaccttcagcaagtatgccatgagctgggtccgcca +5205 JY8QFUQ01A4JI5 productive Homsap IGHV3-48*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 2 8 8 9 8.8.9 [1.17.38.11] CAWGPNGADYW in-frame + ctctggattcaccttcggtaactcaaccatgaactgggtccgccaggctccagggaaggggctggaatggctgtcatatcttagtagtggtggtgatgtcaaatactacgcaggctctctgaagggccgattcaccatctccagagacagtgccaggaactcactgtatctgcaaatgaacagcctgacagacgaggacacggccgtatattactgtgcatgggggcccaacggcgccgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5206 JY8QFUQ01BEWRY No results +5207 JY8QFUQ01CY8X5 unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 933 93.84 198/211 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 7 8 X 7.8.X [X.17.38.11] CARDMGSGRYFGTL#DYW out-of-frame + stop codons attcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttggaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5208 JY8QFUQ01DD5MD No results +5209 JY8QFUQ01C29L1 unproductive Homsap IGHV4-4*07 F, or Homsap IGHV4-59*08 F or Homsap IGHV4-59*10 F or Homsap IGHV4-61*02 F or Homsap IGHV4-61*06 ORF (see comment) 397 84.68 94/111 nt Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD6-19*01 F 3 X X X X.X.X [X.X.37.11] CASTGYTSAPSEWMDV# out-of-frame - Low V-REGION identity (84,68% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tggtggttccatcaccagtgtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaatctgaactctgtgaccgccgctgacacggccgtgtattactgtgcgagtaccggatataccagtgccccaagcgagtggatggacgtctgggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcacccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5210 JY8QFUQ01AZPKZ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 849 88.79 190/214 nt 87.85 188/214 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 7 11 8.7.11 [1.16.38.11] CTRVGTFNWFGPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 92 in the user submitted sequence), (cause frameshift) tctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaagggctggaatgggtcggtggtgttaattggaatggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +5211 JY8QFUQ01CXI17 productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +5212 JY8QFUQ01DTIG3 No results +5213 JY8QFUQ01CZ7HA productive Homsap IGHV4-4*07 F 885 90.65 194/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD4-17*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARDLPTVTTGALDIW in-frame + ctctggtggctccttcagtaattaccactggagctggatccggaagcccgccgggaaggaactggagtggattgggcgtatccatcacagtgggctcaccaactccaacccctccctcaagaatcgagtcgtcgtgtcagtggatacgtccaagaatcagttgtccctggagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagatcttcctacggtgactactggggctcttgatatctggggccaagggacaatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctggactgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactc +5214 JY8QFUQ01A3VGZ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 905 90.83 198/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) gcctcctggattcaccCtttggttattatggcatgactggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5215 JY8QFUQ01A453G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 879 89.09 196/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [2.17.38.11] CVREGAATGSFYYW in-frame - aacctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5216 JY8QFUQ01B4TSK productive Homsap IGHV3-9*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 3 8 8 12 8.8.12 [1.17.38.11] CAKGETVVTPGDYW in-frame + ctctggattcacctttgatgattgtgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagtggcagcatcggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatttacaaatgaatagtctgagacctgaggacacggccttatattactgtgcaaaaggagagacagtggtaactccaggagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5217 JY8QFUQ01AMCYK unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 756 86.93 173/199 nt 86.43 172/199 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD6-13*01 F 2 8 1 12 8.1.12 [1.17.38.11] CAKAPGTATSEDLW in-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 56 of V-REGION: 19 nucleotides (from position 81 in the user submitted sequence), (cause frameshift) cctctggattcagttttcgcagctgtggcatgacctgggtccgccaggctccagggaaggggctgcagtgggtctcaccttttagtgctacgcagactccgtgaagggccggttcagcattttcagagacaactcggagaacacactctatctgcaattgaacagcctgagagccgaggacacggccgtttgttattgtgcgaaagcccccgggacagcaacatctgaggacctctggggccagggaacccaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5218 JY8QFUQ01CKYMP No results +5219 JY8QFUQ01DPTIU productive Homsap IGHV4-61*02 F 929 91.4 202/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARATLSDVDTPLGFDYW in-frame + tctctggtgtctcaatcacgagtggaagtcactactggaattggattcggcagcccgccgggaagggaccggagtggattgggcgtttctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccgtatcagcagacacgtccaagaaccggctctccctgaagctgagatctttgaccgccgcagacacggctgtttattactgtgcgagagcaaccttgtctgacgtggatacacctttgggctttgactactggggccagggaatcttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5220 JY8QFUQ01B8UCZ unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt 92.79 206/222 nt 8 7 X 8.7.X [4.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaagggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaaccccttggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +5221 JY8QFUQ01C84NL unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 106 53.44 70/131 nt 8 8 X 8.8.X [0.17.10.X] null - No rearrangement found stop codons tggattcaccttcagtagatactggatgcactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5222 JY8QFUQ01B7E5F productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARAGYCNNGVCYSSYFDFW in-frame + ctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggtgtgggtctcacgtatgaatagtgatggcagtgacataaggtacgcggactccgtgaggggccgattcaccatctccagagacaacaccaagaacacgctgtatctacaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagcgggatattgtaataatggtgtatgctactccagttactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +5223 JY8QFUQ01CD6QH No results +5224 JY8QFUQ01BM70U productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5225 JY8QFUQ01DL6BO unknown (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F 131 51.44 107/208 nt 8 8 X 8.8.X [2.17.34.X] null - No rearrangement found gcctctggattcaactttgaagattatgccatgtactgggtccgacaacctccagggaagggcctggagtgggtctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5226 JY8QFUQ01CO8HU unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARDCDSGECNFDYW in-frame - stop codons in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); tctgattcagcttcagtacctaGtaacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5227 JY8QFUQ01AK3I6 No results +5228 JY8QFUQ01A3SDR No results +5229 JY8QFUQ01BKSUX productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 1034 98.14 211/215 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-2*02 F 2 8 7 15 8.7.15 [1.17.38.11] CARGVGVSWHTEYFQHW in-frame + cctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagaggggtcggcgtcagctggcatactgaatacttccagcactggggccagggcaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +5230 JY8QFUQ01DS4J6 productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5231 JY8QFUQ01C0KDB unknown (see comment) Homsap IGHV3-52*01 P, or Homsap IGHV3-52*02 P or Homsap IGHV3-52*03 P or Homsap IGHV3-74*01 F or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 121 82.86 29/35 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found gtctggatttaccttcagtaagttctggatgcatt +5232 JY8QFUQ01BJ3SK No results +5233 JY8QFUQ01CI4KV productive Homsap IGHV1-8*01 F 844 88.26 188/213 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [X.17.38.11] CARVGGTHYHYGVDVW in-frame - ggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagatctgacgacacggccgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5234 JY8QFUQ01DJS23 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 865 88.58 194/219 nt 87.21 191/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 18 to 19 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) ggcctcctggattcaccCTttgggttattatggcatggactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5235 JY8QFUQ01CCRES No results +5236 JY8QFUQ01A05FU No results +5237 JY8QFUQ01DPTKE unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +5238 JY8QFUQ01A7O8D No results +5239 JY8QFUQ01BH9L3 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CAKITPL*QEWSII#DYW out-of-frame - stop codons in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctgggtcactttttggccactataccatgagctgggtccgccaggctccagggaAaggggctggagtgggtctcagctattggtaatagtggtgatattacatactacgcagactccgcgaggggccggttcaccatctccagagacaattcccagaacacactgtatctgcaagtgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaataacccccctatgacaggagtggtccattataccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5240 JY8QFUQ01AEEE7 unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 733 82.41 178/216 nt 81.94 177/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [2.17.38.11] CARDLGWKLR*V#YFDYW out-of-frame - stop codons Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); gtccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtCgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagatttggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5241 JY8QFUQ01CTKX9 productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttcccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5242 JY8QFUQ01ATVCJ No results +5243 JY8QFUQ01DVXY4 unproductive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSL*N#DYW out-of-frame - stop codons ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagtttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcaccctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5244 JY8QFUQ01A4KHC No results +5245 JY8QFUQ01BASL4 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 804 86.45 185/214 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD5-24*01 ORF 1 8 7 X 8.7.X [1.17.38.11] CATLRGVLS#Y out-of-frame + ctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagaggggtactttcgactactgggccgggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggccaccctcctccaagagcacctctggggccacagcggccctggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactcag +5246 JY8QFUQ01BB93A No results +5247 JY8QFUQ01ALUXL No results +5248 JY8QFUQ01AW0KM productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5249 JY8QFUQ01A5HXY productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 826 87.79 187/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame - tctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +5250 JY8QFUQ01CVIUK No results +5251 JY8QFUQ01BEK3T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [2.17.38.11] CARDRLTISALDYW in-frame - gcctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +5252 JY8QFUQ01BC75P productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 714 81.78 175/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Low V-REGION identity (81,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcaccatcactcactactccatggcctgggtccgccaggctccggggaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcctcatcatctccagagacgaatccaagagtgagctgtatcttcggatgacgaaagtgaaagccgaagacgcggccgtatattactgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5253 JY8QFUQ01ANKJV productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 874 89.04 195/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-1*01 F 2 8 8 9 8.8.9 [2.17.38.11] CARRQLALAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); catctgggatacacctttatcacctactggatcgcctgggtgcgccaaatgcccgggaAaaggcctggagttgatgggagtcatctatcctggtgactctgagaccagatacagcccgtccttccaaggccacatcaccctctcagtcgacaagtccatcgataccgcctacctggagtggagcagcctgaaggcctcggacaccgccatgtacttctgtgcaagaagacaactggcccttgcctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5254 JY8QFUQ01AT2XH productive (see comment) Homsap IGHV3-33*03 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5255 JY8QFUQ01A7BIA productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 696 80.84 173/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +5256 JY8QFUQ01DQQ3Y productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 94.17 210/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaaGtatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +5257 JY8QFUQ01CFREB unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 876 96.77 180/186 nt 8 8 X 8.8.X [1.17.27.X] null - No rearrangement found ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcca +5258 JY8QFUQ01DQGXH productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 857 89.62 190/212 nt 89.15 189/212 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 7 8 13 7.8.13 [X.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); ttcaccctttgggttattatggcatgagctggatccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5259 JY8QFUQ01BIH2H productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 807 85.45 188/220 nt 85.0 187/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggtgactccatcagtagtactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5260 JY8QFUQ01A72B2 No results +5261 JY8QFUQ01AK8LP productive (see comment) Homsap IGHV4-61*02 F (see comment) 731 81.45 180/221 nt 81.0 179/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 3 9 6 16 9.6.16 [3.17.38.11] CAIERSRSIGGDGQFDFW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (9 AA in JY8QFUQ01AK8LP ; 10 AA in Homsap_IGHV4-61*02), and low V-REGION identity (81,45% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 105 in the user submitted sequence), (do not cause frameshift) tctctgggtgggcccccatcagaggcggtggtttctactggacctggctccggcagtccgccgggaagggcctggagtggatcggacgtatttatgacagtggcagtgactacaatccttctctcaagagtcgagtcaccatgtcagtagacacgtccaagagccagttctccctgaggctgagttctgtggccgccgcagacacggccgtttacttctgtgcgatagaacgtagtagatcgattggcggagacggacaatttgacttctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5262 JY8QFUQ01BKK6X productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - cctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5263 JY8QFUQ01BIGLC productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.16.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccaggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +5264 JY8QFUQ01BGPQC No results +5265 JY8QFUQ01BLMPU productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPAGGSGAYEYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtctctggtattaattggaatggtggtaagacaggttatggagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatttgcaaatgaacagtctgagagccgaggacacggccttgtattactgtgcgagaggccccgccgggggatctggcgcatatgagtactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5266 JY8QFUQ01B35FR unproductive (see comment) Homsap IGHV3-7*01 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-3*01 F 2 8 7 X 8.7.X [1.17.38.11] CARDDDFWEW*T#FDPW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 85 in the user submitted sequence), (cause frameshift) ctctggattcagtcttaataactactggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaatataaaaaagatggaagtgagaaatactatgtggactctgtgaagggccgtttcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagaggcgaggacacggctgtgtatcactgtgcgagagacgacgatttttgggaatggtaaacacttcgacccctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5267 JY8QFUQ01BCSTY unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 779 83.94 183/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5268 JY8QFUQ01CRUKP No results +5269 JY8QFUQ01CCLMC No results +5270 JY8QFUQ01CLS91 unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 130 55.22 74/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5271 JY8QFUQ01B2X20 No results +5272 JY8QFUQ01ACF7K No results +5273 JY8QFUQ01A5JTB No results +5274 JY8QFUQ01A82RF productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 858 89.25 191/214 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame + ctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +5275 JY8QFUQ01AZE1O productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + tccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5276 JY8QFUQ01CS0AM No results +5277 JY8QFUQ01B3CD7 unknown (see comment) Homsap IGHV4-61*02 F 956 92.76 205/221 nt 92.31 204/221 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT at codon 88 of V-REGION: 'A' (1 nucleotides at position 173 to 173 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagtggtagttactactggagctggacccggcagcccgccgggaggggcctggagtggattgggcgtgtccataacagtggtagttccaattacaagccctccctcacgagtcgagtcaccatattagtagacacgtccaagaatcagttctcAcctgaagctgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagagaagcgcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5278 JY8QFUQ01C2CGR No results +5279 JY8QFUQ01BKXOJ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*06 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 796 85.65 185/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [1.17.38.11] CARGDGYNFGGLDSW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tatggattcaacttcattggttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactccgtgaggggccgatccatcatttccagagacgattctaaaagaacactgtttctccaaatggacaacctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5280 JY8QFUQ01C6JUQ productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 6 10 9.6.10 [1.17.38.11] CASHGGKYFPQW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggacaaatccatcatgtgggggcaccaattacaAacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5281 JY8QFUQ01DA6VQ unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcatcttcagtagctactggatgcactggg +5282 JY8QFUQ01CGLQV No results +5283 JY8QFUQ01A5BO8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 940 93.06 201/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + tccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5284 JY8QFUQ01B4DTC No results +5285 JY8QFUQ01B5D43 unknown (see comment) Homsap IGHV3-21*04 F (see comment) 720 81.11 176/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (81,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +5286 JY8QFUQ01C3P0G No results +5287 JY8QFUQ01AL4I4 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARAYSGPG#YYFDYW out-of-frame + ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccaggctcttccccc +5288 JY8QFUQ01C67BE productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 9 7 12 9.7.12 [1.17.38.11] CAANLGHGSYFKYW in-frame + tctctggtgactccgtcagcagtgataactggtggagttgggtccgccagaccccagggaaggggctggagtggattggagaaatctatcatggtgggaccaccaactacaatccgtccctcaagggtcgagtcaccttatcggtcgacaagtccaagaaccaattctctctgagaatgacctcttttaccgccgcagacacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagcctcaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5289 JY8QFUQ01CWHH2 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); gttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgGacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5290 JY8QFUQ01CMRYI No results +5291 JY8QFUQ01AKS4K unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 760 83.8 181/216 nt 82.87 179/216 nt Homsap IGHJ3*01 F 160 80.0 40/50 nt Homsap IGHD6-25*01 F 3 8 7 X 8.7.X [2.17.38.11] CARGTRYNNGLD#FDVW out-of-frame - Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 154 to 154 in the user submitted sequence), (cause frameshift); gtctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtGcccttggcagtcgagtctccatatcactggacacgtcCcaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgctttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5292 JY8QFUQ01BXIJY productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 911 90.5 200/221 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-1*01 F 2 10 7 8 10.7.8 [1.17.38.11] CATVDRLTYW in-frame + tctctggtgtctccatgagcagtcttacttactactggggctggattcgccagccccccgggaagggcctggagtggattgggactctcttttatagtgggagcacctactacaatccgtccctcaggagtcgagtcaccatatccgctgactcgtccaagaaccagttctccctgaacctaaggtctgtgaccgccgcagacacggctgtctatttctgtgcgacggtggatcgactgacctactggggccggggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +5293 JY8QFUQ01C0ACH No results +5294 JY8QFUQ01C79UA No results +5295 JY8QFUQ01A5QCW productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [2.17.38.11] CARGDGVKDDYW in-frame - agtctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5296 JY8QFUQ01DMD7B productive Homsap IGHV3-7*01 F (see comment) 733 82.41 178/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +5297 JY8QFUQ01BD5WV No results +5298 JY8QFUQ01A9VFZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame - ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5299 JY8QFUQ01AZX3F productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-18*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARVGYGYRGIYFFGAYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttggagcctactggggccagggaaccctggtcacccgtgcctcctcagccctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +5300 JY8QFUQ01AEE1F unknown (see comment) Homsap IGHV3-23*05 F 102 55.24 58/105 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons cctctggattcgtctttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5301 JY8QFUQ01AXVYW No results +5302 JY8QFUQ01CY70Q unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +5303 JY8QFUQ01C8JUC No results +5304 JY8QFUQ01DTA7K productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca +5305 JY8QFUQ01DVBU0 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaaggttcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +5306 JY8QFUQ01A9MNS productive (see comment) Homsap IGHV3-66*02 F (see comment) 760 83.8 181/216 nt 83.33 180/216 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-21*01 F 3 8 7 11 8.7.11 [2.17.38.11] CARHLMVYALDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gtctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaggGggctggagtgggtctcagtcttatttagtactggcactgcatactacgcagactccgtgaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5307 JY8QFUQ01AD07C productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 775 84.02 184/219 nt 83.56 183/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); tgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGgggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5308 JY8QFUQ01BRGBS productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 927 92.17 200/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) gtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5309 JY8QFUQ01CUJMD productive Homsap IGHV3-48*02 F 1026 97.24 211/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD1-1*01 F 2 8 8 20 8.8.20 [1.17.38.11] CASGERKDYEVRRDYYHGMDVW in-frame + ctctggactcaccttcagcagctatagtatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatatattagtagtactagtagtaccataaactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagtggggaaaggaaagactacgaagtacgacgggactactatcacggcatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +5310 JY8QFUQ01AE4G5 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 7 8 17 7.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) tctggattcagtttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +5311 JY8QFUQ01ANPDJ productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5312 JY8QFUQ01DMRYE unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaagccctggctnaccgtctcctcagcatcccccgaccagccccaaagggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +5313 JY8QFUQ01CSZHP unknown (see comment) Homsap IGHV3-74*03 F, or Homsap IGHV3-NL1*01 F 141 57.5 69/120 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaaggtcttcccgctgagcctcgatagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttctt +5314 JY8QFUQ01A1GZY productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 856 88.13 193/219 nt 87.67 192/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 7 8 17 7.8.17 [2.17.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) agcctctggattcagtttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5315 JY8QFUQ01ASYTM unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 924 93.36 197/211 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 7 8 X 7.8.X [X.17.38.11] CANACPPV*LE#YFYYYGMDVW out-of-frame - stop codons attcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacatatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctgcccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5316 JY8QFUQ01CZQGS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5317 JY8QFUQ01DN3JU unknown (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaacccgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +5318 JY8QFUQ01CL6OG productive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 803 86.38 184/213 nt 85.92 183/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.37.11] CARRSTSGDKFDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 70 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tggagggaacttcaacaattatggtttcagctgggtgcgacaggcccctggacaaggccttgagtggatgggagaaatcatcccattttttggaacatcaaaatanacacagaattccagggcagactctccattaccgcggacgaatccacgagcacagcctttatggacttgagtggcctgagatctgaggacacggccgtctattattgtgcgagaaggtctactagtggggataaatttgacttctggggccagggaagccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5319 JY8QFUQ01AOC88 No results +5320 JY8QFUQ01DSF5L productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 870 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - agcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5321 JY8QFUQ01CBJNI No results +5322 JY8QFUQ01DNDQ8 No results +5323 JY8QFUQ01AXQMT unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 429 76.87 113/147 nt 8 8 X 8.8.X [1.17.14.X] null - No rearrangement found Low V-REGION identity (76,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctacgtggtcgtcgcatgcctggtccagggcttcttccccca +5324 JY8QFUQ01CZY00 No results +5325 JY8QFUQ01A2B2A productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1002 96.73 207/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - tctgggtggctccatcagtagttactactggagctggatccggcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5326 JY8QFUQ01CFHFO No results +5327 JY8QFUQ01BE70Q No results +5328 JY8QFUQ01AN3ES productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame + ctctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgctggtcccagggcttcttccccca +5329 JY8QFUQ01B66LL unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CAREKVRAPP#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtcttctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5330 JY8QFUQ01CYN05 No results +5331 JY8QFUQ01A7AKD unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-7*01 F 2 8 8 X 8.8.X [1.17.38.11] CATGAGNWNY#FNYW out-of-frame + ctctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtggtttttatatatactacgcggattcagtgaagggccgagtcaccatctccagagacaacgccaagaattcgctatttctgcaaatgaacaacctgcgagccgaggacacggctgtctattactgtgcgacaggggccggaaactggaattacattttaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5332 JY8QFUQ01DOSRH productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 738 82.49 179/217 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +5333 JY8QFUQ01B82UI productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +5334 JY8QFUQ01B3U51 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccctgaccagccccaaggtcttcccgctgagctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5335 JY8QFUQ01B7J6Z unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +5336 JY8QFUQ01B731P productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 803 86.79 184/212 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [0.17.38.11] CARGRTVVTVIDYIDYW in-frame + ctggggactccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +5337 JY8QFUQ01DKJWG productive (see comment) Homsap IGHV3-21*04 F 836 87.91 189/215 nt 86.98 187/215 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD3-16*01 F 2 7 8 10 7.8.10 [1.17.37.11] CAREVSDALDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 93 of V-REGION: 1 nucleotides (from position 183 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaattctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtgcagggccgattcaccatctccagagacaacgacaacaacgtcctgtatctgcaaatgaacagttgagacccgaggacacggccttgtatcgctgtgcgagagaggtttcggacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5338 JY8QFUQ01CQP3F productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5339 JY8QFUQ01CQW8C productive Homsap IGHV4-61*02 F 988 94.14 209/222 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARGSGSGSYSNLW in-frame - ctctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5340 JY8QFUQ01BXULP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKAGRGLIRPNNWFDPW in-frame + ctctggattcacctttagtagttctggcatgtattgggcccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatgccacaaattacgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcggggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5341 JY8QFUQ01AIJPD No results +5342 JY8QFUQ01BZC5P productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccggaaccaggtgacggtgtcgtggaactc +5343 JY8QFUQ01CV8A6 No results +5344 JY8QFUQ01DFT66 productive (see comment) Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 749 82.27 181/220 nt 81.82 180/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 3 10 7 15 10.7.15 [2.17.37.11] CARVWVAGSRDENFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 165 in the user submitted sequence), (cause frameshift) gtctcgggtgcttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgccctgtcattagacgcgtctaataatgtttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5345 JY8QFUQ01CDRM8 No results +5346 JY8QFUQ01DI90L productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDPYNGGGYGAFDIW in-frame + ctctggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccatcataaagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgcaaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagacccctataatggtggtggttatggtgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgggtccagggcttcttccccca +5347 JY8QFUQ01CQ3ZM productive Homsap IGHV3-48*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDMIIFGGALDNW in-frame + ctctggattcatctttgatgattttggcatgaattgggtccgccagggtccagggaaggggctggagtggatttcacacattaggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggagcccttgacaactggggccagggaaccctggtcaccgtctcctctgcatccccggaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +5348 JY8QFUQ01ASYBM No results +5349 JY8QFUQ01A7RIF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5350 JY8QFUQ01CPVXS unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 719 81.86 176/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (81,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5351 JY8QFUQ01A0364 No results +5352 JY8QFUQ01BZUN4 unknown (see comment) Homsap IGHV3-30*07 F 892 89.95 197/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. gcctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5353 JY8QFUQ01A8AJT productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CMNEFGYCSGGG in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 89 of V-REGION: 'T' (1 nucleotides at position 171 to 171 in the user submitted sequence), (cause frameshift); gctctggattcacttttagcagccatatgatgacttgggtccgccaggctccagggaaggggctggaatgggtcgcaagtattcgtgccagtggtggtaggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgttgtatTttgcaaatgtacagtctgagagtcgaggacacggccttatattattgtatgaacgaattcggatactgtagtggtgggggggcccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +5354 JY8QFUQ01DKKPO No results +5355 JY8QFUQ01A4MZ9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVKGWNYHSATFGFDYW in-frame + ctctggattcacctttagtgactatgccataagctgggtccgccaggctccaggaaaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccattttcagagacaactccaaagacacgctgtatctgcaaatgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaacctttgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5356 JY8QFUQ01DOZMM No results +5357 JY8QFUQ01C2K80 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 2 9 7 11 9.7.11 [1.17.38.11] CARASTLRYLDRW in-frame - tctctggtggctccatcagcagtgataattggtggagttgggtccgccagcccccagggaagggactggaatggattggggaaatatatcatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacaagtccaagagtcaattcttcctggagctgaggtctgtgaccgccgcggacacggccgtatattattgtgcgagagcctccacactacgatatcttgaccgctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5358 JY8QFUQ01APMVK productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5359 JY8QFUQ01BGOQC unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 139 88.57 31/35 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found tctacattcgcctttagcaactatgccatgagctg +5360 JY8QFUQ01BT6UT unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 455 87.29 103/118 nt 8 8 X 8.8.X [1.17.4.X] null - No rearrangement found cctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcttccccca +5361 JY8QFUQ01C7XJ3 unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F 570 92.42 122/132 nt 91.67 121/132 nt 10 7 X 10.7.X [1.2.23.X] null + No rearrangement found in FR2-IMGT, from codon 39 of V-REGION: 44 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) ctctagtgactccatcagcagtactaattactactgggagtatgtatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctga +5362 JY8QFUQ01AZLXE No results +5363 JY8QFUQ01ATV1R productive (see comment) Homsap IGHV3-7*02 F 907 91.59 196/214 nt 90.19 193/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*02 F 3 8 8 13 8.8.13 [1.16.38.11] CARLSGRIRNAFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 30 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 75 in the user submitted sequence), (cause frameshift) ctctggatttacctttagtagtaactggagacgtgggtccggccngctccagggaagggctggagtgggtggccacataaagatggatggaagtgagcattactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtatctggaaatgcacagcctgagagccgaggacacggctctgtattactgtgcgagactctcgggacggatccgcaatgctttcgatctctggggccaagggacaatggtcactgtctctttagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5364 JY8QFUQ01AB8J9 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + ctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5365 JY8QFUQ01BOHQR No results +5366 JY8QFUQ01CXUN7 No results +5367 JY8QFUQ01CUGZN unknown (see comment) Homsap IGHV5-51*05 F 149 56.62 77/136 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found gttctgcatatagtttttccagttactggatcgcctgggtgcgccagatgcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5368 JY8QFUQ01BVN36 No results +5369 JY8QFUQ01A9LJF unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 589 77.66 153/197 nt 77.16 152/197 nt 8 8 X 8.8.X [1.17.31.X] null - No rearrangement found Low V-REGION identity (77,66% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift); ctccgaattcatccttgacagttatgccatgGagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5370 JY8QFUQ01BA5EZ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 919 91.32 200/219 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) gcctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccttgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5371 JY8QFUQ01CBM5L No results +5372 JY8QFUQ01BC6EZ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 614 76.42 162/212 nt 7 8 X 7.8.X [X.17.38.X] null - No rearrangement found Low V-REGION identity (76,42% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5373 JY8QFUQ01A9MMF productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + ctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +5374 JY8QFUQ01AYSO6 productive Homsap IGHV4-61*02 F 947 92.31 204/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame - tctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatgtcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5375 JY8QFUQ01AEMXL productive (see comment) Homsap IGHV3-23*05 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccccca +5376 JY8QFUQ01B6ATU productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 993 94.17 210/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcgaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5377 JY8QFUQ01ADXSU unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 353 86.17 81/94 nt 8 5 X 8.5.X [1.17.X.X] null - No rearrangement found ctctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc +5378 JY8QFUQ01CYQNH No results +5379 JY8QFUQ01A3HNF No results +5380 JY8QFUQ01AOELI No results +5381 JY8QFUQ01DAVHO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDPGNYWGYYYDS## out-of-frame + ctctggattcacctttagcagttatgccatgagctgggtccgccagactccagggaaggggctggagtggatctcagaaattactggtgatggcgataacatatactacgcagactccgtgaagggccgtttcaccatctccagagacaattccaagaacactctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatccggggaactattgggggtactactatgactcttgggggcctgggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5382 JY8QFUQ01AWYM5 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 858 89.25 191/214 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame + ctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5383 JY8QFUQ01CD9JY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVKGWNYHSATFGFDYW in-frame + ctctggattcacctttagtgactatgccataagctgggtccgccaggctccaggaaaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccattttcagagacaactccaaagacacgctgtatctgcaaatgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaacctttgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5384 JY8QFUQ01DNNFM No results +5385 JY8QFUQ01AB19P productive Homsap IGHV3-7*01 F 846 88.02 191/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRDRPGGWALDYW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactca +5386 JY8QFUQ01BQ174 No results +5387 JY8QFUQ01CU36E productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1047 99.07 212/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + ctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +5388 JY8QFUQ01DKUMI productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 847 87.67 192/219 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD6-6*01 F 1 8 8 16 8.8.16 [2.17.38.11] CVRRGRQDTDSSEAFDIW in-frame - ggctctggatacacctttggcattcactggattgcctgggtgcgccagaagcccgggaaaggcctagagtggatggggatcatctatccaggcgactctgacaccacatacagtccgtccttccaaggccaagtcaccatctcagtcgacaagtccagcaataccgcctatttacagtggatcagcctgagggcctcggacaccgccatgtattattgtgtgagacggggcagacaagataccgactcgtctgaagcttttgacatttggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5389 JY8QFUQ01DE1OM productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactca +5390 JY8QFUQ01AC35C No results +5391 JY8QFUQ01AB26V unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 418 96.63 86/89 nt 8 3 X 8.3.X [1.17.X.X] null + No rearrangement found ctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagta +5392 JY8QFUQ01DQ8CK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcanttccccgaaccggtgacggtgtgcgtggaactca +5393 JY8QFUQ01CXLSN No results +5394 JY8QFUQ01DRP9X No results +5395 JY8QFUQ01C6Z4J No results +5396 JY8QFUQ01AE1E1 productive Homsap IGHV3-49*04 F 984 93.72 209/223 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-15*01 F 1 8 10 11 8.10.11 [1.17.38.11] CTPWWRGGYFDYW in-frame + ctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaaccatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtaccccgtggtggcggggaggttactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaaaccgtggtcgtcgcatgcctggtccagggcttcttccccca +5397 JY8QFUQ01DA71E productive Homsap IGHV3-64*02 F (see comment) 784 84.47 185/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-9*01 F 2 8 8 16 8.8.16 [2.17.38.11] CVRGRPMAGFHGILYDNW in-frame - Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggatttagtatcagtaattatggtattcactgggtccgccaggctccagggaggggactggaacttgtttcagctattaccaacaatgcgcatagtgtagtctatgtagactctgtgaagggcagattcatcatctccagagactattccaagaacacgttgtatcttcaaatgggcagactgagaccagaagacacggctgtgtactactgtgtcagagggcggcctatggctggctttcatggaatcctttatgacaactggggcctgggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5398 JY8QFUQ01ATRK5 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaatgacacgtttgggagagaagactactgggggccagggaacccgtggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +5399 JY8QFUQ01A7WON unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 588 81.36 144/177 nt 8 8 X 8.8.X [1.17.24.X] null - No rearrangement found Low V-REGION identity (81,36% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccgaaccggtgacggtgtcgtgga +5400 JY8QFUQ01B6T0H productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 776 83.71 185/221 nt 83.26 184/221 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFESW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'TC' (2 nucleotides at position 54 to 55 in the user submitted sequence), (cause frameshift); tttccggtgactccatcaccagtactaattattactggggctgggtccgccagTCccccaggggaagggtctggagtggattggaagtgtctattatcgggggacccagtacctcaacccgtctctccacaatcgagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtcttttggagtgataattgttaactactttgagtcctggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactca +5401 JY8QFUQ01BWHD3 No results +5402 JY8QFUQ01BHIPV productive (see comment) Homsap IGHV3-23*05 F 805 86.11 186/216 nt 85.19 184/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKSTGHSGWYPFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); tctggattcacAgttcagcaattatgccatgggctgggtccgccaggctccagggaaggggctggagtAgggtcgctgctattgatggcagtggtgaaagaactcactatgcagactccgaacagggccgcgtcaacatctctagagacaattccaagaacatgatatatgtgcaattgagcagcctgagagccgaggacacggccatgtattactgtgtgaagtccaccgggcacagtggctggtatccctttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +5403 JY8QFUQ01CH60H productive (see comment) Homsap IGHV3-7*01 F 943 93.9 200/213 nt 92.96 198/213 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [0.16.38.11] CTTTLVWFGEL (see Functionality comment) in-frame + Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) tggattcacgtttagagactattggatgagttgggtccgccaggctcctgggaggggctggagtgggtAggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +5404 JY8QFUQ01BUI58 productive (see comment) Homsap IGHV1-3*01 F 531 88.24 120/136 nt 87.5 119/136 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 X 13 8.X.13 [0.3.34.11] CARDGYRSGNGADYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 78 nucleotides (from position 35 in the user submitted sequence), (do not cause frameshift) tggatacagcttcactaactacaatatccattggaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +5405 JY8QFUQ01BHU4V unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ3*01 F (see comment) 133 74.0 37/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CANELGYCSG## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctagagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccgaaggtcttgccccgctgagcctctgcagcaacccacgccagatgggaacatggtccatcgcctgcctggtccagggcttcttccccc +5406 JY8QFUQ01BE2CW No results +5407 JY8QFUQ01CX2NZ unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 112 53.73 72/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5408 JY8QFUQ01C05JS unknown (see comment) Homsap IGHV3-49*01 F, or Homsap IGHV3-49*03 F or Homsap IGHV3-49*05 F 92 52.31 68/130 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons ttctggattcacctttggtgactatgctatgagctggttccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +5409 JY8QFUQ01C5S68 No results +5410 JY8QFUQ01C9UUV No results +5411 JY8QFUQ01C1E93 No results +5412 JY8QFUQ01BHV6G unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 657 77.88 169/217 nt 77.42 168/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.37.X] null - stop codons no junction found Low V-REGION identity (77,88% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 169 in the user submitted sequence), (cause frameshift) tctctggattcacccttcgcagatatggcatggcgtgggtccgccaggctccggggaaggggctggagtgggtctcatcttctaacagtagtgatgaatccacatactatgcagactccgtgaagggccgcttcaccatttccagagaccattccaagaacacggtgttttgcaaatgtacagcctggggccagggagccctggtcaccgtctcccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5413 JY8QFUQ01CRSSS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAKEIAVSGEGALDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); gcctctggattcacAgtttagcaactatgccatgagctgggtccgccaggctccagggaaggggccggagtgggtctcagctattactggtcttgatggtagaacattctacgcagactccgtgaagggccgtttctccatctccagagacaattccaagaacacgttgtatttgggaatgaacagcctgagagccgaggacacggccgtatattattgtgcgaaagagatagcagtgagtggtgagggggcgttggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5414 JY8QFUQ01CVV8C unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +5415 JY8QFUQ01BUF2K No results +5416 JY8QFUQ01BBZ8A unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 535 92.06 116/126 nt 91.27 115/126 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD1-20*01 F 1 8 X X 8.X.X [1.6.26.11] CANASPV*LERI#YYYGMDVW out-of-frame + stop codons Other possibilities: Homsap_IGHJ3*01 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 45 of V-REGION: 91 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctcccccgtataactggaacgtatttctactactacggtatggatgtctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +5417 JY8QFUQ01B1XL8 No results +5418 JY8QFUQ01CUJY2 No results +5419 JY8QFUQ01B09KA productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5420 JY8QFUQ01CQA8U No results +5421 JY8QFUQ01BNAB7 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 889 91.08 194/213 nt 90.61 193/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); tcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgatcagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5422 JY8QFUQ01C8G2P unproductive (see comment) Homsap IGHV3-48*01 F 891 90.32 196/217 nt Homsap IGHJ1*01 F (see comment) 107 67.31 35/52 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CARESTWEFYS*LL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcagtttcagtgactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagttctagtagtaccctatattatgcagactctgtgaagggccgattcaccgtctccagagacaatgacaagagttctctgtatctgcaaatgaccggcctgagagccgaagacacggcgacttattactgtgcgagagagtcgacgtgggaattttactcctgactcctggggcccgggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5423 JY8QFUQ01ACIGI unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 484 82.86 116/140 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (82,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag +5424 JY8QFUQ01C10O9 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 678 79.91 171/214 nt 78.97 169/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 71 of V-REGION: 'C' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'AGT' (3 nucleotides at position 137 to 139 in the user submitted sequence), (do not cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccCgtgaggggcgggcttatcgaAGTctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +5425 JY8QFUQ01AWKYO No results +5426 JY8QFUQ01DRPQO productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + ctctggattcacttttagcagtttttggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagtgggatggaagtgataaaaagtatatggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactatatctgcaaatgaacagcctgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaatgatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +5427 JY8QFUQ01DJVMH unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 795 84.3 188/223 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 X 8.10.X [1.17.38.11] CATDFPYWI##AFDVW out-of-frame + stop codons Low V-REGION identity (84,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctgcattcactttcagtaatgcctggatgacctgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggatttcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5428 JY8QFUQ01ATUBK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAMRFCGGPECYPYLDNW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcacattcagtaactactggatccactgggtccgccaagctccaggaaaggggctagagtgggtcgcacgtattaatgatgctggaaagcgtgccgacttcgcgactttcgtgaagggccgattctccatctcccgagacaacgccaagaacacagtgtatctggaaatgactagtctgagagtcgacgacacggctgtctatttttgtgcaatgcgattttgtggtggtcctgagtgctacccttatcttgacaactggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +5429 JY8QFUQ01B15FC No results +5430 JY8QFUQ01BV55D productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5431 JY8QFUQ01DH0MW productive Homsap IGHV3-74*03 F 1031 97.25 212/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [1.17.38.11] CATGPDYAYAMW in-frame - cctctggattcaccttcagtcgctactggatgcactgggtccgccaagctccagggaagggcctggtgtgggtctcacgtattaaaagtgatgggattagcacaacgtacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtactactgtgcaaccgggcccgattatgcgtatgctatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5432 JY8QFUQ01B47NI productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 285 82.35 70/85 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame + Low V-REGION identity (82,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5433 JY8QFUQ01B2UDS No results +5434 JY8QFUQ01APY5Z productive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5435 JY8QFUQ01CLWT1 No results +5436 JY8QFUQ01C5V24 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1031 97.25 212/218 nt 96.79 211/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD1-26*01 F 3 8 8 18 8.8.18 [1.17.38.11] CAKELGRALTGNYYQYFHYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcacgttcagtggctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtatcatatgatggaagtaataaatactatgcagactccgtgaagGggccgattcaccatctccagagacaattccaagaacacgctctctctgcaaatgaacagcctgagagctgaggacacggctgtatattactgtgcgaaagaattggggagggccctgactgggaactactaccagtactttcactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5437 JY8QFUQ01BF7T6 unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F or Homsap IGHV1-69*01 F or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F 86 57.53 42/73 nt 56.16 41/73 nt X X X X.X.X [24.X.X.X] null + No rearrangement found in FR1-IMGT, from codon 7 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggcggctgtgntctcggaggtgctcctggagcagggcgccagggggaagaccgatgggcccttggtggaggtgacgaagccaccagaga +5438 JY8QFUQ01B92KA unproductive Homsap IGHV3-72*01 F 1078 98.65 219/222 nt 98.2 218/222 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.16.38.11] CLRPPRYD#PG out-of-frame + in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +5439 JY8QFUQ01CB12R No results +5440 JY8QFUQ01C9J7X unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 107 55.66 59/106 nt 8 8 X 8.8.X [1.17.X.X] null + No rearrangement found stop codons cctctggattcaccttcagtcgttatagcatgaactgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +5441 JY8QFUQ01CBHZ7 unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARLGATR##DYW out-of-frame + stop codons ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttggggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaccggtgacggtgtcgtggaactc +5442 JY8QFUQ01BX3WN unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 110 100.0 22/22 nt 6 X X 6.X.X [1.X.X.X] null + No rearrangement found ctctggattcactttcagtaac +5443 JY8QFUQ01A65SY No results +5444 JY8QFUQ01BNPNB productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctcag +5445 JY8QFUQ01AMD1U productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5446 JY8QFUQ01DEEWB productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5447 JY8QFUQ01BY1KT unknown (see comment) Homsap IGHV3-38-3*01 ORF 102 53.03 70/132 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons tgtctggattctccgtcagtttcaactacatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5448 JY8QFUQ01CST8T productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASDLGGQKSYW in-frame + ctcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtagtcgtcgcatgcctggtccagggcttcttccccca +5449 JY8QFUQ01C3FXA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5450 JY8QFUQ01BGOY9 No results +5451 JY8QFUQ01AR5SV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccacaagggcccatcggtcttcccctggcacctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5452 JY8QFUQ01DCHJ0 No results +5453 JY8QFUQ01BKRRW unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 446 66.97 146/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (66,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gctctggattcagtatttataattattggatgaattgggtccgccaggctccagggagggggctggagtgggtggccagcattaaggcagacggaactgagaagacgtttggggactctgtgaagggccgattctccatctccagagacaacgcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +5454 JY8QFUQ01C05FJ productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 705 81.31 174/214 nt 80.84 173/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,31% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 77 of V-REGION: 'T' (1 nucleotides at position 132 to 132 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttgaTcgatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5455 JY8QFUQ01CI830 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttcccccgaaccggtgacggtgtcgtggaacctcag +5456 JY8QFUQ01AR9UF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5457 JY8QFUQ01AMUMN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 13 8.8.13 [1.17.38.11] CTRDSVSGDLVIDFW in-frame + ctctggattcaacttcaatttctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcgtctatcagtagaagtagtaattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaacaactctctgcatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtacgagagattccgtgtccggtgacttagtcattgacttctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5458 JY8QFUQ01BAY6G productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccaggggcttcttccccctagg +5459 JY8QFUQ01A0N2T unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 664 93.96 140/149 nt 8 8 X 8.8.X [1.17.15.X] null + No rearrangement found tctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaa +5460 JY8QFUQ01CGA88 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD3-3*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKQTIFDYYYGLDVW in-frame + ctctggattcatgtttagtagctttcccatggcctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5461 JY8QFUQ01C3V50 productive Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame + Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +5462 JY8QFUQ01CQ0U4 unproductive (see comment) Homsap IGHV3-7*02 F 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CATSPLR*LLGRT#YW out-of-frame - stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaagGggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctcccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +5463 JY8QFUQ01CS3O4 No results +5464 JY8QFUQ01BF7BK unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 123 68.42 39/57 nt 8 X X 8.X.X [1.9.X.X] null + No rearrangement found ctccggattcacctttagtagttactggatgcactgggtccagggcttcttccccca +5465 JY8QFUQ01CCHUM No results +5466 JY8QFUQ01CTP5B No results +5467 JY8QFUQ01CQY5C unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 401 77.21 105/136 nt 76.47 104/136 nt 8 6 X 8.6.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (77,21% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) cctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5468 JY8QFUQ01A7ZGP unknown (see comment) Homsap IGHV3-48*03 F 873 89.4 194/217 nt 88.94 193/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtaGgttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5469 JY8QFUQ01BBZI9 productive Homsap IGHV3-74*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +5470 JY8QFUQ01BBDCQ productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAYFSTGYW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5471 JY8QFUQ01BN5VO productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 849 88.79 190/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [0.17.38.11] CACYFDSNGFFDYW in-frame + tggatacgtctttccctcctactggatcgcctgggtgcgccagatgcccggtaaaggcctggagtggctgggaaccatctatcccggcgactctgacaccacatacagcccgtcattccaaggccaggtcaccatgtcagtcgacacgtccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacagcgccatttactattgtgcgtgttattttgatagtaatggtttctttgactactggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5472 JY8QFUQ01CJX2H No results +5473 JY8QFUQ01DU4YW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatggccgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5474 JY8QFUQ01CAS0F No results +5475 JY8QFUQ01CBQ8X unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +5476 JY8QFUQ01CIE27 No results +5477 JY8QFUQ01ATA2C productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5478 JY8QFUQ01A7EEO No results +5479 JY8QFUQ01C38VZ No results +5480 JY8QFUQ01C6HDO No results +5481 JY8QFUQ01A38E4 No results +5482 JY8QFUQ01BBQPP No results +5483 JY8QFUQ01DRF9S No results +5484 JY8QFUQ01ATS0K No results +5485 JY8QFUQ01CPR0X No results +5486 JY8QFUQ01BQXYU productive Homsap IGHV3-11*01 F 882 89.86 195/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVDIRLGDWFFDLW in-frame + ctctggattcatcttcagtgaccactacatgagctgggtccgccaggctccggggaagggtctggagtggatctcatacatcagtacaagtggtaatatggtttattacgcggactctgtgaagggccgattcaccgtctccagggacaacgccaagaactcactgtatctgcaaatgaacggcctcagagtcgaggacacggccgtctattactgtgtcgacataagactgggtgattggttcttcgatctctggggccgtggcaccctggtaactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5487 JY8QFUQ01A261C No results +5488 JY8QFUQ01BHG7H unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKVSSYESSGYYGGLF*LL# out-of-frame + stop codons ctctggattcacctttaccagctatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtgccagtggtggtagcacatactacgaagactccgtgaagggccggttcaccatctccagagacaattccaagaacaccctgtatcttcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagtttcgtcctatgagagtagtggttattacggggggttattttgacttctggggtccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5489 JY8QFUQ01DV3UL unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 701 80.93 174/215 nt 80.47 173/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*02 F 3 8 7 X 8.7.X [1.17.38.11] CARAYTFHFWSGL##WYFDLW out-of-frame - Low V-REGION identity (80,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaggGggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatacttttcacttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5490 JY8QFUQ01DR4X2 No results +5491 JY8QFUQ01CKYJ1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +5492 JY8QFUQ01BZF3C No results +5493 JY8QFUQ01BE43V unknown (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5494 JY8QFUQ01B26IH unproductive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*03 F 567 94.49 120/127 nt 93.7 119/127 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 X X 8.X.X [0.3.31.11] CARGGRRGNYYWGI#DSW out-of-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 35 in the user submitted sequence), (do not cause frameshift) tggatacacgttcaccgactactatgtccactggggcagggtcaccatgaccagggacacgtccatcagcacagccttcatggagctgagcagcctgagatctgacgacacggccgtttattactgtgcgagaggggggcgacgtgggaactattattggggaatcttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5495 JY8QFUQ01DSXYM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKDRITIFSYNWFDPW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5496 JY8QFUQ01C3J6T unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 121 96.15 25/26 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found ctccggggacagtgtctctaccaaca +5497 JY8QFUQ01CNKUO unproductive (see comment) Homsap IGHV3-48*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARAGGWEI##YFDYW out-of-frame + stop codons ctctggattcatcttcagtcagtataaaatgaattgggtccgccaggctccagggaaggggctggagtgggtttcagaaattagttttagaagcagaaccgtacactacgcagactctgtgaggggccgcttcaccgtctccagagacaatgccaagaactcactgtatctacaattgaacagcctgagagacgaggacacggctatatattactgtgcgagagcggggggctgggagattcgactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5498 JY8QFUQ01DU2D9 productive Homsap IGHV3-9*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + ctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccctatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +5499 JY8QFUQ01DSQKK productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYHFDYW in-frame + ctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5500 JY8QFUQ01CDMAR No results +5501 JY8QFUQ01AJRGU productive Homsap IGHV1-69*04 F, or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69*10 F or Homsap IGHV1-69*14 F 822 87.38 187/214 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [0.17.38.11] CAIPFSSSSAWFDPW in-frame + tggaggcaccttcagcagctatgtcatcagctggctgcgacaggcccctggacaagggcttgagtggatgggacatgtcattcctatgtttggtgtatctaacctcgcgcagaggttccagggcagagtcacaataaccgcggacacatccacgaccacagcctacatggaggtgaccaggctgagatctgaagacacggccgtctattattgtgccataccattcagcagctcgtcggcctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5502 JY8QFUQ01CVCX4 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1025 97.67 210/215 nt 97.21 209/215 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaagccctggctcaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +5503 JY8QFUQ01DVB70 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame + Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcagcgtctcctctgcatccccgaccagccccaaggtcttcctgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5504 JY8QFUQ01BYIVH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 652 92.16 141/153 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 X 8 13 X.8.13 [X.5.38.11] CARDCDSGECNFDYW in-frame + ctctgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5505 JY8QFUQ01BRVZA productive Homsap IGHV3-7*01 F 1003 96.3 208/216 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDVW in-frame + tctggattcaccttcagtagcctttggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaatataaaacaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgggagccgaggatacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5506 JY8QFUQ01C68XM No results +5507 JY8QFUQ01BFND9 No results +5508 JY8QFUQ01B23M7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 7 17 8.7.17 [1.17.38.11] CAKKYHYGSGTYYYHFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) ctctggattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcgcaactattattatagtggcgatagtacatactacgcagattccgtgaggggccggttcaccatctccagagacaattccaagaacactctgcatctgcatatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaaagtatcactatggttcggggacttattattaccacttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5509 JY8QFUQ01BBV45 No results +5510 JY8QFUQ01CAWQU No results +5511 JY8QFUQ01A9MZ5 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 768 82.96 185/223 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 13 8.10.13 [1.17.38.11] CATDSPTGYYAFDVW in-frame + Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctgggttcgttttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +5512 JY8QFUQ01BM2LN productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 928 91.78 201/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-7*01 F 3 8 8 13 8.8.13 [2.17.38.11] CATGAGNWNYIFNYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); gcctctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgGgtttttatatatactacgcggattcagtgaagggccgagtcaccatctccagagacaacgccaagaattcgctatttctgcaaatgaacaacctgcgagccgaggacacggctgtctattactgtgcgacaggggccggaaactggaattacatttttaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5513 JY8QFUQ01CITNO productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5514 JY8QFUQ01ADJUL unproductive (see comment) Homsap IGHV3-7*01 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-23*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CATSP*RL*QTMGVLG in-frame + stop codons in FR2-IMGT at codon 50 of V-REGION: 'GTG' (3 nucleotides at position 63 to 65 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); ctctggatttagctttagaaccttttggatgagctgggtccgccaggctccaggggaggggcGTGgagagtgggtggccaaTcataaagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctccccctagcgactttgacagacgatgggggtactgggggcccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5515 JY8QFUQ01CCWJO productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARHSHSSGYSSLDALEIW in-frame + ttctgcatatagtttttccagttactggatcgcctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatcaatcccggtgactctgataccagatatagcccgtcctttcaaggccaggtcaccgtctcagccgacaggtccatcagtaccgcctacctgcagtggaaaagcctgagggcctcggacaccgccatgtattactgtgcgcgacactcccacagtagtggttattccagccttgacgctcttgagatctggggccaagggacaatggtcaccgtctcttctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5516 JY8QFUQ01CH5B1 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 937 92.24 202/219 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [2.17.38.11] CARGMATAESW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gcctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +5517 JY8QFUQ01AWVZF productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 554 92.97 119/128 nt 92.19 118/128 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-10*01 F 3 8 X 21 8.X.21 [1.8.25.11] CARLTPLTMVPGTHYYYHSMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 87 nucleotides (from position 54 in the user submitted sequence), (do not cause frameshift) tctctggtggctccatgactggttactactggagttggatccggcggcccccagtcgacacgtccaagaaccagttctctctgacgctgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagattgacacccctgactatggttccgggaactcactactattaccacagtatggacgtctggggccaagggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaagg +5518 JY8QFUQ01DQWVS No results +5519 JY8QFUQ01C8IQT No results +5520 JY8QFUQ01AZYT3 No results +5521 JY8QFUQ01CX8D2 productive (see comment) Homsap IGHV3-33*02 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ1*01 F 197 86.54 45/52 nt Homsap IGHD6-6*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARDRQDARAEHLQYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 170 to 170 in the user submitted sequence), (cause frameshift); ctggattcatcttcagtaattatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggctgttctgtggttcaatggaaatacgaagtattatgcagactccgtgaagggccgcttcaccatctccagagacacatccacgaacacgctgtttttCgcaaatggacagcctgagagccgaggacacggctgtctattattgtgcaagagatcgtcaggacgcccgcgctgaacatctccaatactggggccagggcaccatggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttccccca +5522 JY8QFUQ01A9CSP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD6-25*01 F 1 8 8 22 8.8.22 [1.17.38.11] CARYQGDTSGYQDVFYAHYGMDVW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacttttaggggctactggatgcactgggtccgtcaggttccaggtaaggcgccggagtggctcgcacgtctgaatactgatggagatagtacaagttatgcggactccgtgaagggccgcttcaccatctccagagacaacgccaggagcacattgttcctgcaaatgagcagtctgagagtcgaagacacggccatttattactgtgcacggtatcagggcgataccagtggctaccaggacgttttctacgcccactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgccctggtccagggcttcttccc +5523 JY8QFUQ01CMEIS No results +5524 JY8QFUQ01A6HZE unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F (see comment) 612 75.58 164/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5525 JY8QFUQ01CVDDP unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 445 67.13 145/216 nt 66.67 144/216 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found Low V-REGION identity (67,13% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5526 JY8QFUQ01A5HLC No results +5527 JY8QFUQ01B5CX5 No results +5528 JY8QFUQ01DRKQS unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CARLGPRFGD*LL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 43 of V-REGION: 'C' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctactggagctggatccCggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggccccggttcggggactgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5529 JY8QFUQ01DFFHG No results +5530 JY8QFUQ01DJSOV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggctttttccccca +5531 JY8QFUQ01AEXEP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.16.38.11] CANWLSGTHSKFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggagggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc +5532 JY8QFUQ01B53L4 No results +5533 JY8QFUQ01DEZRE productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5534 JY8QFUQ01A99VZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [2.17.38.11] CARGGLEPVDYW in-frame - ccctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5535 JY8QFUQ01C43MC unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 442 93.07 94/101 nt 8 7 X 8.7.X [1.17.X.X] null + No rearrangement found ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgaca +5536 JY8QFUQ01DQ69Q productive Homsap IGHV3-30*07 F, or Homsap IGHV3-30*08 F or Homsap IGHV3-30*16 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame + ctctgcattcaccttcagtagttatgctatgcactgggtccgccaggccccaggcaaggggctagagtgggtggcagttatatcaaatgatggaaattataacgactatgcagactccgtgaaggggcgattcaccatttccagagacaactccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5537 JY8QFUQ01BCX6J No results +5538 JY8QFUQ01CVXWU No results +5539 JY8QFUQ01CH61H No results +5540 JY8QFUQ01DW494 No results +5541 JY8QFUQ01AA6MU No results +5542 JY8QFUQ01AND5D unknown (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ6*03 F (see comment) 37 65.0 13/20 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Other possibilities: Homsap_IGHJ5*02 (shorter alignment but highest percentage of identity). The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtcgctatggcatgcactgggtccgccaggctccagggaaggGggctggcatgggtttcatacattagtgccagtagcagcaccaagtactacgcaaattctctgaagggccggttcaccatctccagagacaacgccaagaattcactgtatctggaaatcaacagcctgagcgacgaggacacgtctgtgtattactgtgcgcgagatgactacggcttcttcccca +5543 JY8QFUQ01AURX4 No results +5544 JY8QFUQ01CHUA2 productive Homsap IGHV3-7*01 F 1007 96.74 208/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [0.17.38.11] CAISSGFYSTGYW in-frame + ctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc +5545 JY8QFUQ01A85B5 No results +5546 JY8QFUQ01AFMGL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5547 JY8QFUQ01AKHRY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +5548 JY8QFUQ01CVICZ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 116 55.65 64/115 nt 8 8 X 8.8.X [1.17.3.X] null - No rearrangement found gctctggattcagctttagttactattggatgagctgggtccgccaggctcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5549 JY8QFUQ01BE4S7 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFDP## out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccaggggaaccctggtcaccgtctcctcagcctccaccaagggcccagctcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +5550 JY8QFUQ01CW7P5 No results +5551 JY8QFUQ01AUUYT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5552 JY8QFUQ01BT3YG No results +5553 JY8QFUQ01BO21D productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5554 JY8QFUQ01APXOX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKRLQAVADDAFDFW in-frame - ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgagcagcctgagagccgaagacacggccatatattactgtgcgaaaaggttgcaagcagtggctgatgatgcttttgatttctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5555 JY8QFUQ01BUMGI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 651 99.25 132/133 nt 98.5 131/133 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 87 64.58 31/48 nt 8 X 17 8.X.17 [1.11.24.11] CAKFMGVVVVPAAHNWFDP (see Functionality comment) in-frame + Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION in FR2-IMGT, from codon 50 of V-REGION: 84 nucleotides (from position 62 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaagggagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctgggccaggaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5556 JY8QFUQ01CJ47C No results +5557 JY8QFUQ01CD2OW No results +5558 JY8QFUQ01CKCGQ unproductive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRGGRGSSE#DAFDIW out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatgggagtgagaaatactatgtcgactcagtgaggggccgatttaccatctccagagacaacgccgagagctcactgtatctgcagatgagcagcctgagagccgaggacacggctttatattattgtgtgagaggcgggaggggcagcagcgagaagatgcttttgacatttggggccaagggacaagcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5559 JY8QFUQ01DH95Z unproductive (see comment) Homsap IGHV4-61*02 F 882 89.86 195/217 nt 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [1.17.37.11] CARDPRVICSGGSCRSSAMDV* in-frame + stop codons Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 158 in the user submitted sequence), (cause frameshift) tccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaaccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagaccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctgaggccaagggaccacggtcaccgtctcctcagcctccaccaaggggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +5560 JY8QFUQ01CYI8T productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + ttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5561 JY8QFUQ01CAW0A No results +5562 JY8QFUQ01ATEPS No results +5563 JY8QFUQ01DSN81 unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 719 85.28 168/197 nt 84.77 167/197 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) tctgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgga +5564 JY8QFUQ01CN7CX No results +5565 JY8QFUQ01A4GBM No results +5566 JY8QFUQ01AARSO No results +5567 JY8QFUQ01B4Z07 No results +5568 JY8QFUQ01DO78T No results +5569 JY8QFUQ01BJ5JH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 894 91.12 195/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 7 8 10 7.8.10 [1.16.38.11] CARDLYGADDLW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) ctctggattcaccttagtagatattggatgcactgggtccgccaagctccagggaagggctggtgtggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctcgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5570 JY8QFUQ01AG0MF No results +5571 JY8QFUQ01BAWN2 No results +5572 JY8QFUQ01BLWFY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +5573 JY8QFUQ01DV8FJ No results +5574 JY8QFUQ01DKH5M unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 423 91.92 91/99 nt 10 4 X 10.4.X [1.17.X.X] null + No rearrangement found tctctggcggctccatcagcagtactagttactactggacctggattcgccagcccccagggaaggggctggagtgggttgggagtgtctattatactg +5575 JY8QFUQ01C1FN1 unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARGQNGYKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgcgagaggtcaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5576 JY8QFUQ01B775N productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [2.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); gtctctggattcaccgtcaataGggaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5577 JY8QFUQ01CRJBD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ5*02 F 109 70.21 33/47 nt Homsap IGHD5-12*01 F 3 8 8 6 8.8.6 [1.17.38.11] CVSIGHGV in-frame + ctctggattcgcctttaggagtgagtggatgaactgggtccgccaagccccagggaaggggctggagtgggtcgcacacattgacactgatgggagtatcgcagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaatactttgtatctgcaaatggacagtctgagagccgacgacacggctatatattactgtgtaagcattggacacggagtgggcccgggaacccaggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +5578 JY8QFUQ01BBTQQ productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +5579 JY8QFUQ01ATJ6D productive (see comment) Homsap IGHV3-11*01 F 1004 95.87 209/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARGYSYGCFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'GGAGGGACT' (9 nucleotides at position 91 to 99 in the user submitted sequence), (do not cause frameshift); cctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaTggggctggagtggatttcaaacatcaatagtGGAGGGACTagtgggaggaccatatattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagaggatacagctatggctgctttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +5580 JY8QFUQ01DGOQL productive Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 735 81.74 179/219 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 10 7 18 10.7.18 [1.17.38.11] CAKDKWYYDSSGYQYYLDSW in-frame + Low V-REGION identity (81,74% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctcgggtgcttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgccctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgaaagacaaatggtactatgatagtagtggttatcaatactaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5581 JY8QFUQ01DN3IK No results +5582 JY8QFUQ01CAFUF No results +5583 JY8QFUQ01BP2N9 productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.16.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gcctctacattcacgtttagtcggtattggatgagctggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5584 JY8QFUQ01DEFDV unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); gcctccggattcaccGtttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccctca +5585 JY8QFUQ01BTSMS No results +5586 JY8QFUQ01AUPU3 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5587 JY8QFUQ01CEFXQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVKEDHDSGLRVLLEW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 51 of V-REGION: 'AG' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift); ctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggaggggcgtggaAGgtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacaacctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5588 JY8QFUQ01ALW7I productive (see comment) Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 99.07 214/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5589 JY8QFUQ01B9N93 productive Homsap IGHV3-9*01 F 787 85.19 184/216 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-9*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVKDLSGRPKDMHGMDVW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) tctgggttcagttttagcaattatgccatgcactgggtccgtcaagctccagggaagggcctgcaatgggtctcacgtattaattggaacagtggaaacatagcctatgcggcctctgtgaggggccgattcaccgtctccagagacgacgccgagcactccctgtatttacaaatgaatggtctgacaactgaagacacggccttatactattgtgtgaaagatttgtctggccgaccaaaggacatgcacggcatggacgtctggggccaagggaccacggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaaacgtggtcatcgcctgcctggtccagggcttcttccccca +5590 JY8QFUQ01C65QU productive (see comment) Homsap IGHV3-7*03 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 7 8 8 7.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctccggattcattttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca +5591 JY8QFUQ01C1QRL No results +5592 JY8QFUQ01C1IP6 No results +5593 JY8QFUQ01CSU0E No results +5594 JY8QFUQ01C1YFI productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYYYYDTNGDYW in-frame - ctctggatttacctttacaaattattggatgagctgggtccgccaggctccagggagggggctggagtgggtggccagcgtaaaacaagatggaggtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggtcctactattattatgatactaatggcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5595 JY8QFUQ01DU77L productive (see comment) Homsap IGHV3-7*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [2.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) gcctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5596 JY8QFUQ01CDQJC unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ6*04 F 99 64.81 35/54 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [1.17.38.11] CMNELGYCSG## out-of-frame + ctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtggggggcagggaggccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +5597 JY8QFUQ01BNCCQ productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +5598 JY8QFUQ01COPIL No results +5599 JY8QFUQ01BJBTV productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 84.62 187/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtGactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5600 JY8QFUQ01A1BK7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +5601 JY8QFUQ01DER7D No results +5602 JY8QFUQ01ASNS2 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 930 92.99 199/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 7 16 8.7.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame + ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5603 JY8QFUQ01B7YKQ No results +5604 JY8QFUQ01ASIHL No results +5605 JY8QFUQ01AP72B productive (see comment) Homsap IGHV3-7*01 F (see comment) 742 82.87 179/216 nt 82.41 178/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5606 JY8QFUQ01BDAG5 No results +5607 JY8QFUQ01CZVO7 productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [2.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'GA' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift); agtctctggattcaccgtcaatagGAaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5608 JY8QFUQ01CWJGM No results +5609 JY8QFUQ01CJTJ0 No results +5610 JY8QFUQ01BZ8WK productive Homsap IGHV3-66*02 F 868 89.35 193/216 nt Homsap IGHJ1*01 F 206 88.46 46/52 nt Homsap IGHD6-19*01 F 2 8 7 13 8.7.13 [2.17.38.11] CAAVGVGSAVSFQYW in-frame - gcctctggcttcaccgtcaataacaactacatgggctgggtccgccaggctccagggaaggggctggagtgggtctcgattatttattacggtggaaccacatattacgctgactccgtgaagggccgattcaccatctctagagacacctccaagaacacgttatttcttcaaatgaataccctaagaggtgaggacacggctgtgtactactgtgcggcagtcggagtgggaagtgcagtctccttccaatactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5611 JY8QFUQ01BHPIN No results +5612 JY8QFUQ01A04UM No results +5613 JY8QFUQ01AGS3S No results +5614 JY8QFUQ01BUS72 unproductive Homsap IGHV3-21*04 F 909 91.24 198/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-7*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGEGQGWNY#YYGMDVW out-of-frame - ctctggattcactttcagtaacgtctggatgcactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcatcatctccagggacaacgccaagaactcactgtctctgcagatgaacagcctgagagccgacgacacggccgtctattattgtgctcggggggaagggcaagggtggaactacctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5615 JY8QFUQ01ASD77 productive Homsap IGHV3-43*01 F 949 93.52 202/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 142 76.0 38/50 nt Homsap IGHD3-16*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKWAPTGVMGPMPLIFG in-frame + tctggattcatatttgaagactataccatgcactgggtccgtcaagctccggggaagggtctggagtgggtctctcttattaattgggatggtggtaacacatactatgcagactctgtgaagggccgattcaccatctccagagacaacaacaagaactccctgcaaatgcaaatgaacagtctgagaactgacgacaccgccttgtatttttgtgcaaaatgggctcctacgggagttatgggtccgatgcctttgatttttggggcccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +5616 JY8QFUQ01DXF5F productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1110 100.0 223/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD4-17*01 F 3 8 10 12 8.10.12 [1.17.38.11] CTKCSVTIYFLTTG in-frame + ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttactttttgactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +5617 JY8QFUQ01AVPIU unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 81 56.94 41/72 nt 8 X X 8.X.X [1.14.X.X] null - No rearrangement found ctctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5618 JY8QFUQ01BAMJG productive Homsap IGHV1-24*01 F 988 96.24 205/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame - ggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5619 JY8QFUQ01BVBT9 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 871 87.84 195/222 nt 87.39 194/222 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD1-14*01 ORF 1 8 10 X 8.10.X [1.17.37.11] CTADVPSPLAQNDF# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 166 in the user submitted sequence), (cause frameshift) ctctggattcactttcaatggcgcctggatgaactgggtccgccaggctccagggaagggtctggagtgggttgcccgtataaaaacttttggtgaaggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcaaaaaagggctgtatctgcagatggacagcctgagaatcgaggacacagccaagtattactgcaccgcagatgtcccgtcaccattagcgcaaaatgacttctgggccagggaaccctggtcaccgtctcctcagnatccccggacagccccaaaggtcttcccgctgagcctccgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5620 JY8QFUQ01C3X43 No results +5621 JY8QFUQ01BZNDE productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.16.38.11] CARDPVGISGSVNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaagggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5622 JY8QFUQ01C0HLO unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 882 89.86 195/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD3-3*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDYYDGRDYV# out-of-frame + gtctggattcaaattcaacagcagtggcatgcactgggtccgccaggctccaggcaagggactggagtggctgtcagttatatggtttgatggcagtcatcaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactttttctgcagatggacagcctcagagtcgaagacacggctgtctattactgtgcgagagactactatgatggtcgtgattatgtctgggccacggaaccctggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5623 JY8QFUQ01DCZXP productive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5624 JY8QFUQ01CZ46G No results +5625 JY8QFUQ01DV3XT unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD4-11*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CARDSALFGYARYDAMDA## out-of-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggcccaagggaccgcggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggctcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5626 JY8QFUQ01BPLRY unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 450 67.28 146/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (67,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5627 JY8QFUQ01CR28R productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5628 JY8QFUQ01AZS32 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt 86.05 185/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); tctctggtgGgctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5629 JY8QFUQ01AV2VI productive (see comment) Homsap IGHV3-48*03 F 823 87.04 188/216 nt 86.57 187/216 nt Homsap IGHJ6*02 F (see comment) 185 81.82 45/55 nt Homsap IGHD1-1*01 F 3 7 8 10 7.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) ctctggattcgccttcaaagttttaacatgaattgggtccgccaggcttcagggaaggggccggagtggattgcatacattaatggaagagggactaacatctactatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctctgcagcaccccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccccagg +5630 JY8QFUQ01BDYY2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-16*02 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGQFGTVMDYW in-frame + ctctgggttcacctttagcagctatgccatgacttgggtccgccaggctccagggatggggctgcagtgggtcgcaaccattagtggaagtggcgacagaacattctacgcagactccgtgaagggccgcttcatcgtttccagagacaactccaagaacacgctgtatctgcaaattaccagcccgagagccgaggacacggccgttttttattgtgcgaaaggccagtttggtaccgtcatggactattggggccagggaacccaggtcgtcgtctcctcagcatccccgaccagccccaaggtcttcctgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5631 JY8QFUQ01DJPXI productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5632 JY8QFUQ01B6KS0 productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5633 JY8QFUQ01CBHVO productive Homsap IGHV1-8*01 F 921 92.52 198/214 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [0.17.38.11] CARARGVESSGIYVYHFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggatacaccttcaccacttatgacatcaactgggtgcgacaggccgccggacaagggcttgagtggatgggatgggtgaaccctgtcactggtaacacaggctatatacagaagttccagggcagagtcaccatgaccatgagcacctccacaagcacagcctacatggagctgagcagcctgaaatctgacgacacggccgtgtattattgtgcgagagcccggggggtagaaagttcggggatctacgtgtatcactttgactcctggggccagggaaccctggtcaccgtctcctcagcatcccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +5634 JY8QFUQ01CEIHZ productive Homsap IGHV1-3*01 F (see comment) 351 73.53 100/136 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 X 7 14 X.7.14 [X.X.38.11] CARGRYDSSGRGHEYW in-frame - Low V-REGION identity (73,53% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcaccagtttcagtatccattggaagttccaggacagactcaccattactagagacacatccgcgagcacagcctacatggacctgagcagcctgagatctgaagacacggctgtctattactgtgcgagagggcgctatgatagtagtggtcgtggccatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5635 JY8QFUQ01AW8CJ No results +5636 JY8QFUQ01B715G No results +5637 JY8QFUQ01DKFB0 productive Homsap IGHV3-21*04 F 959 93.58 204/218 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSHQVDVW in-frame - cctctggattcgcctttaatacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttgatagtacttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacaacctgagagccgaagacacggccgtgtattactgtgcgagagccgtttcgcatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5638 JY8QFUQ01B1M13 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 559 93.02 120/129 nt 92.25 119/129 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-10*01 F 3 8 X 21 8.X.21 [2.8.25.11] CARLTPLTMVPGTHYYYHSMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 87 nucleotides (from position 55 in the user submitted sequence), (do not cause frameshift) gtctctggtggctccatgactggttactactggagttggatccggcggcccccagtcgacacgtccaagaaccagttctctctgacgctgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagattgacacccctgactatggttccgggaactcactactattaccacagtatggacgtctggggccaagggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5639 JY8QFUQ01CG8MB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt 86.11 186/216 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +5640 JY8QFUQ01BDRV8 No results +5641 JY8QFUQ01BIY56 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAIEHTLPSGQGLGIEYFW in-frame - gcctctggattcaactttaacagctttgccatgagctgggtccgccaggttccagggatggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactccgtgaagggccggttcaccatctccagagacaactccaacaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgatcgagcatacccttccgtccggacagggattagggattgaatatttctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5642 JY8QFUQ01BAU9M productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5643 JY8QFUQ01CN8OF unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F (see comment) 607 75.46 163/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,46% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5644 JY8QFUQ01DAM03 unproductive (see comment) Homsap IGHV1-2*02 F 915 92.89 196/211 nt 92.42 195/211 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 7 8 15 7.8.15 [X.17.37.11] CARGGRRGNYYWES*LW in-frame + stop codons in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) gatacacgttcaccgactactatgtccactgggtgcgacaggcccctggacaagggcttgagtggatggcgtggatcaaccctaacattggtgtcaccaagtctgcacaaaatttcagggcagggtcaccatgaccagggacacgtccatcagcacagccttcatggagctgagcagcctgagatctgacgacacggccgtttattactgtgcgagaggggggcgacgtgggaactattattgggaatcttgactctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +5645 JY8QFUQ01DCJ87 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 148 53.19 100/188 nt 8 7 X 8.7.X [2.17.28.X] null - No rearrangement found gcctctggattcaccttcagttctcacactatgaactgggtccggcaggctccagggaaggggccggagtgggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5646 JY8QFUQ01CNSR0 No results +5647 JY8QFUQ01CA64I No results +5648 JY8QFUQ01ASWWE No results +5649 JY8QFUQ01DLV58 No results +5650 JY8QFUQ01DMF5R productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKRLQAVADDAFDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaTcctttagtagctatgccatgggctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgagcagcctgagagccgaagacacggccatatattactgtgcgaaaaggttgcaagcagtggctgatgatgcttttgatttctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5651 JY8QFUQ01C0P6M No results +5652 JY8QFUQ01BGM91 No results +5653 JY8QFUQ01B4OGW productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcca +5654 JY8QFUQ01CT9DG No results +5655 JY8QFUQ01CAVOQ productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgagaacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5656 JY8QFUQ01AHJIA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtccgtggaactcag +5657 JY8QFUQ01C870Y No results +5658 JY8QFUQ01BV6IJ unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5659 JY8QFUQ01DIAOX productive Homsap IGHV3-9*01 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame + ctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5660 JY8QFUQ01A0ARS No results +5661 JY8QFUQ01ASCOV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +5662 JY8QFUQ01APIM1 unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 418 84.48 98/116 nt 82.76 96/116 nt 8 7 X 8.7.X [1.17.5.X] null + No rearrangement found Low V-REGION identity (84,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 85 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift) tctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgttctacttacaccatttctacgcagagtctg +5663 JY8QFUQ01CX9WG No results +5664 JY8QFUQ01CKAO6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 928 91.78 201/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [2.17.38.11] CAKLGVAATTWNFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'GCC' (3 nucleotides at position 47 to 49 in the user submitted sequence), (do not cause frameshift); ccgtctggattcacctttaccacctGatgccatgagctgggctccgGCCagggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5665 JY8QFUQ01DU0GX No results +5666 JY8QFUQ01BIRVF No results +5667 JY8QFUQ01A3W95 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5668 JY8QFUQ01CZJPK No results +5669 JY8QFUQ01CCDPI No results +5670 JY8QFUQ01BKBQY productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 1 8 8 11 8.8.11 [1.17.38.11] CVRHTAMERGDYW in-frame - ttctggatatgactttatcaactactggatcggctgggtgcgccagatgcccgggagaggcctggaatggatgggaatcatctttcctgatgactctgatgccagatatagtccgtccttccagggccacgtcaccatctcagccgacaagtccacaagcaccgcctacctggagtggagcagcctgaaggcctcggacaccgccatctactactgtgtgagacatacagctatggagaggggtgactactggggcccgggaaccctggtcaccgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +5671 JY8QFUQ01BYXN5 No results +5672 JY8QFUQ01CAF5A productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 951 92.73 204/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - agcctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5673 JY8QFUQ01CGP6U No results +5674 JY8QFUQ01B8JVX No results +5675 JY8QFUQ01DJE9I productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F (see comment) 723 80.72 180/223 nt 79.82 178/223 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 10 13 8.10.13 [1.17.38.11] CSTGGPNGYHSTYPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'CT' (2 nucleotides at position 49 to 50 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); ctctggattcgccttcaatatcaagtggatgagttgggtccgccaggcCTggccggggaagggcttgagtgggtcggccgcatcaagagcagcgctgatggtgcgacaacagacaccattgagcgcgtgagagacagattcaccatctcaagagatgactcaaaaaaGtacactgtacttgcacatgaccggcctgagaaccgaggacacaggcatgtattattgttccacaggcgggccaaatggatatcactccacatatccctggggcccggggacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5676 JY8QFUQ01ATCC4 No results +5677 JY8QFUQ01AE1S4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame + ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5678 JY8QFUQ01A3YHO productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 806 85.78 187/218 nt 84.86 185/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.37.11] CARRWARQRLVMDYFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 89 of V-REGION: 1 nucleotides (from position 173 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 92 of V-REGION: 1 nucleotides (from position 183 in the user submitted sequence), (cause frameshift) ctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctcctgaggttgagtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtggaactca +5679 JY8QFUQ01CJPMP productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 909 91.24 198/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-16*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARVGWADYRDTFEIW in-frame + ttctggatacacttttcccaactattggatcgcctgggtgcgccagatgcccgggaaagacgtggagtggatggggatcatctatcctgacgactctgacaccgcgtacagcccgtccttccaaggccaggtcaccatctcagtcgacaagtccatcagtaccgtctacttgcagtggaacagcctgaaggcctcggacaccgccatgtattactgtgcgagggtcggctgggcggattaccgggatacttttgaaatctggggccaagggacaatggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5680 JY8QFUQ01A12V0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +5681 JY8QFUQ01DDE1I productive (see comment) Homsap IGHV3-48*01 F 991 94.98 208/219 nt 94.06 206/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'CG' (2 nucleotides at position 72 to 73 in the user submitted sequence), (cause frameshift); gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaTggggctggagtCGggatttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5682 JY8QFUQ01DQEVL No results +5683 JY8QFUQ01A05HF unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgccagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +5684 JY8QFUQ01CJF89 productive (see comment) Homsap IGHV3-48*01 F 923 91.74 200/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 15 8.8.15 [2.16.38.11] CAKVGSMNIEASPPDDW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gtctctggattcaGcgttcagttcctatagcatgagctgggtccgccaggctccggggaagggctggagtgggtctcatatattagtagtagtggtaggaccatctactacgctgactccgtgaagggccgattcaccatgtccagagacaatgccaagaattcactgtatctacaaatgaacagcctgagagccgaggacacggccgtctattactgtgcgaaagttggcagcatgaatatcgaggcgagccctcctgacgactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5685 JY8QFUQ01A3HBC No results +5686 JY8QFUQ01A9OA6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5687 JY8QFUQ01ALKF4 productive (see comment) Homsap IGHV4-61*02 F 833 87.16 190/218 nt 86.24 188/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 10 7 15 10.7.15 [1.17.37.11] CARDTGQTYGRGPLDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 125 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 215 in the user submitted sequence), (cause frameshift) ctctggtgcctccataaataggggtaattattactggaactggatccggcagcccgccgggaagggcctggaatggattggccgaatctatacaagtgggagcaccatctacaacccctccctcggggtcgagtcaccatgactgtagacccgtccgagaatcagttcttcctgagactgagttctgtgaccgccgcagacacggccgtttattttgtgcgagagacactggacaaacctacggtcggggccctttggactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5688 JY8QFUQ01BOE5V productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame - ctctggattcaccttcagtagctatagcatgaattgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5689 JY8QFUQ01DOOXI No results +5690 JY8QFUQ01CTNAN productive Homsap IGHV4-39*02 F (see comment) 758 82.81 183/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 10 7 22 10.7.22 [1.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame + Low V-REGION identity (82,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtatctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgaggtgtcgtggaact +5691 JY8QFUQ01AGKAA productive (see comment) Homsap IGHV3-33*03 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5692 JY8QFUQ01B0WSW No results +5693 JY8QFUQ01DEZDE productive Homsap IGHV4-61*01 F 969 93.64 206/220 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD4-17*01 F 2 10 7 14 10.7.14 [1.17.38.11] CARCDYGDFDDAFDLW in-frame + ctctggtggctccgtcagaagtgggaattactactggagctggatccggcagcccccagggaagggactggagtccattgcatatatctcttacagtgggagcaccacctacagcccctccctcaagggtcgagtcaccatatcagtagacacatccaagaaccagttctccctgagcctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgaggtgtgactacggtgactttgatgatgcttttgatctctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5694 JY8QFUQ01CIJWA unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 123 68.42 39/57 nt 8 X X 8.X.X [1.9.X.X] null - No rearrangement found ctccggattcacctttagtagttactggatgcactgggtccagggcttcttccccca +5695 JY8QFUQ01CQBJM unproductive Homsap IGHV3-48*02 F 1036 97.26 213/219 nt 96.8 212/219 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-3*01 F 1 8 8 X 8.8.X [2.17.38.11] CAREITILD#GVDVW out-of-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift); gcctctagattcaccttcagtagctatagcatgGaactgggtccgccaggctcgagggaaggggctggagtgggtttcatacatcagtggtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagagattacgattttggataggtgtggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5696 JY8QFUQ01C2DN4 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*07 F 835 86.04 191/222 nt 85.59 190/222 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-14*01 ORF 2 8 10 13 8.10.13 [1.17.37.11] CTADVPSPLAQNDFW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 85 of V-REGION: 2 nucleotides (from position 167 in the user submitted sequence), (cause frameshift) ctctgggggtcaccttcagtgacgcctggatgaactgggtccgccaggctccagggaagggtctggagtgggttgcccgtataaaaacttttggtgaaggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcaaaaaaggctgtatctgcagatggacagcctgagaatcgaggacacagccaagtattactgcaccgcagatgtcccgtcaccattagcgcaaaatgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5697 JY8QFUQ01AYOU8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 755 83.72 180/215 nt 82.79 178/215 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.16.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift) gtctggatcacatttagaagctattccagaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggAtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctcaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactnag +5698 JY8QFUQ01B9O0K unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F or Homsap IGHV7-81*01 ORF 134 58.49 62/106 nt 57.55 61/106 nt 8 8 X 8.8.X [0.16.2.X] null + No rearrangement found in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) cggttacattgttaccacctctggtttcagctgggtgcgacaggccctggacaaggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5699 JY8QFUQ01DIGET productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5700 JY8QFUQ01DUQ53 productive (see comment) Homsap IGHV3-7*01 F 895 90.74 196/216 nt 89.81 194/216 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD4-23*01 ORF 3 8 8 12 8.8.12 [1.17.38.11] CARGTSVDPGIDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GG' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift); tctggattcaccTtttagtaattattggatgcactgggtccgccaggtttcaggggaGGggggctggagtgcgtggccaccataaacgaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactctctgtttttgcagatgaacagcctgagagccgaggacacggctgtctactactgtgcgagagggacctcagtggacccggggattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5701 JY8QFUQ01DWYS5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgAaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5702 JY8QFUQ01B0JP3 No results +5703 JY8QFUQ01BWTPC unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [0.17.38.11] CARDNYGDY## out-of-frame - in CDR2-IMGT at codon 62 of V-REGION: 'CG' (2 nucleotides at position 90 to 91 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCGgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5704 JY8QFUQ01ADY64 No results +5705 JY8QFUQ01DPHPE No results +5706 JY8QFUQ01A1183 productive Homsap IGHV4-61*02 F 857 87.78 194/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 11 10.7.11 [1.17.38.11] CARSGWDNQFDFW in-frame + tctctggtgtcgccaccagtagtggcacttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaacccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5707 JY8QFUQ01DH71V productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 807 85.45 188/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + ctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca +5708 JY8QFUQ01CT7CJ No results +5709 JY8QFUQ01DF1RT unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag +5710 JY8QFUQ01CAWGX No results +5711 JY8QFUQ01CGVI4 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 760 83.8 181/216 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [2.17.38.11] CARERGSGPPTGMDVW in-frame - Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ggttatgggttgaccgtcggtgccgaccacatgtactggtgccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaagaggttcggggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5712 JY8QFUQ01DB2VE productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt 89.14 197/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 65 to 65 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaAggggctggagtggaTttgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +5713 JY8QFUQ01CFBXF No results +5714 JY8QFUQ01B710M productive Homsap IGHV4-61*02 F 987 94.55 208/220 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame - ctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5715 JY8QFUQ01ACSDM No results +5716 JY8QFUQ01DDK6P productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 974 93.67 207/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARHGSGWLQELDYW in-frame + tctctggtggctccatcatcagagacagtgcctactggggctggatccgccagcccccagggaaggggctggagtggcttgggagcatctattatagtgggagtacctactacaatccctccctcaagagtcgagtcaccatatccgtagacacgtccaagaagcagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagacatggcagtggctggctccaggaacttgactactggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +5717 JY8QFUQ01DSPOV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt Homsap IGHJ1*01 F (see comment) 116 69.23 36/52 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKSAPHYGSGSYTKD## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaatcggctccccactatggttcggggagttatacaaaagattgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +5718 JY8QFUQ01C026R No results +5719 JY8QFUQ01AKG4H productive (see comment) Homsap IGHV4-61*02 F 875 90.57 192/212 nt 88.21 187/212 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 7 13 8.7.13 [1.16.37.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'TGGTTA' (6 nucleotides at position 23 to 28 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 111 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 209 in the user submitted sequence), (cause frameshift) tctccggtggctccatcagtacTGGTTAttactactgGgagctggatccggcagtccgccgggaagggactgaatggattgggcgcatgtctgccagaggggacagcaactacaaccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtattttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5720 JY8QFUQ01CF631 unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1039 96.0 216/225 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD1-26*01 F 1 10 9 X 10.9.X [1.17.38.11] CARGSSRGGRSDVNYYELDF## out-of-frame + tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggcctcgagtggctgggaaggacatactacaggtccaagtggtattatgactatgcagtgtctgtccaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagctgaattctgtgactcccgaggacacggctgtgtattactgtgcaagagggtccagccgcggggggagatctgatgtgaactactatgagctggacttctggggccaggggaatcctggtcaccgtctcctcagcatccccgaccagcccaaggtcttccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcagggcttcttcccccc +5721 JY8QFUQ01BO8GF unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 650 83.24 154/185 nt 82.7 153/185 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD4-11*01 ORF 3 X 8 X X.8.X [X.15.38.11] DSRNPRV# out-of-frame - Low V-REGION identity (83,24% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); agtgggtccgccaggctccagggaaggggctggagtgggtctcagGgcgtttgtggaagtgctcctaccacacactacgcagactccgtgaagggccggttcagcatctccagagacctctccaagaatgttctgtttctgcaaacgagcagcctgagagccgaggacacgaccgttttttctgactccagaaatcccagggtaggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5722 JY8QFUQ01CGI06 No results +5723 JY8QFUQ01CB3OD productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +5724 JY8QFUQ01BA1XT No results +5725 JY8QFUQ01BLD4K productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +5726 JY8QFUQ01DDLX7 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +5727 JY8QFUQ01DHSQI productive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 10 7 22 10.7.22 [1.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame - Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5728 JY8QFUQ01CIOEQ unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRAGFGELSGFDC## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggGggagggggctgaagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggtccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5729 JY8QFUQ01C5RGO No results +5730 JY8QFUQ01BTQMW No results +5731 JY8QFUQ01DU06W productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); cctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaggggtggAtaccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5732 JY8QFUQ01B4AO7 No results +5733 JY8QFUQ01A9KBS productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 929 91.4 202/221 nt 90.5 200/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 14 10.7.14 [1.17.38.11] CARRALDSSGHYIDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); tctctggtggctccatgagcagtggtaattactgctggggctggggccgccagccCcccaggaaaggggctggagtggattggaagtatgtgttatggtgggagcacctactacagcttgtCcccccaagggtcgagtcaccatatccatagactcgtcgaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagacgcgcattagacagtagtggtcattacattgacatctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggttcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +5734 JY8QFUQ01A33R5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 981 94.93 206/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaGggggctggtgtgggtctcacgtgtatatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5735 JY8QFUQ01ASBP2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5736 JY8QFUQ01CE8RF No results +5737 JY8QFUQ01CNLH7 No results +5738 JY8QFUQ01AOGK9 unproductive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDGSAIPVTGTYFGIL# out-of-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttggaatactggggccaggggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctggctgcctggtcaagactacttcccgaaccggtgacggtgtcgtggaactcagg +5739 JY8QFUQ01B8IR4 No results +5740 JY8QFUQ01CH4BC unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDNYGDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5741 JY8QFUQ01BJ29C No results +5742 JY8QFUQ01CWN98 No results +5743 JY8QFUQ01BIHAR unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 353 86.17 81/94 nt 8 5 X 8.5.X [1.17.X.X] null + No rearrangement found ctctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc +5744 JY8QFUQ01BVE56 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 913 91.2 197/216 nt 90.28 195/216 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.16.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 76 to 78 in the user submitted sequence), (do not cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaagggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgatggtgtcgtggaactcag +5745 JY8QFUQ01DXHAD No results +5746 JY8QFUQ01B1PGP No results +5747 JY8QFUQ01DBCEI productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1031 95.15 216/227 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD7-27*01 F 3 10 9 13 10.9.13 [1.17.38.11] CVRDVGWGLDTLDIW in-frame - tctccggggacagtgtctccagcaacagtgctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatattacaggtccaagtggtacactgattatgcactttctgtgaaaagtcgaataaccatcaacccggacacatcaaagaaccacttctccctgcagctcaactctgtgactcccgaggacacggctctgtattactgtgtaagagacgtcggctggggacttgatactcttgatatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5748 JY8QFUQ01DFRKG productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 804 86.45 185/214 nt 85.98 184/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CGTSSRAWALMPLISG in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); ctctgggctcagcgtcagtaactaccgcatgggctgggtccgccaggctccagggaaggggctggagtgggCtctcagttatttatagagatgatagtacagatcatgtagattccgtgaagggccgattcaccgtttcccgagacaattccaagaacacattgtaccttcagatgaacagtgtgacagccgaggacacggccgtttattattgtggaactagttcccgcgcctgggcgctgatgcctttgatatctggggcccaggggacactggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccccca +5749 JY8QFUQ01DE8MP No results +5750 JY8QFUQ01AL0W5 No results +5751 JY8QFUQ01C4OTS unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +5752 JY8QFUQ01CJZ68 No results +5753 JY8QFUQ01ACOXP No results +5754 JY8QFUQ01AQIAM productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactc +5755 JY8QFUQ01BWVS1 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 830 86.43 191/221 nt 85.97 190/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); ctctaatgggctccatcagcCggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5756 JY8QFUQ01ALJK1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +5757 JY8QFUQ01BKNWV No results +5758 JY8QFUQ01AXLVO productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'AT' (2 nucleotides at position 82 to 83 in the user submitted sequence), (cause frameshift); cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacgaaATtcaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5759 JY8QFUQ01ADJWN No results +5760 JY8QFUQ01ASTE5 No results +5761 JY8QFUQ01DWYRX No results +5762 JY8QFUQ01DQNN6 No results +5763 JY8QFUQ01A0XKT unproductive Homsap IGHV3-7*01 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CVRGRDGVNFGEMDY## out-of-frame - in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tctgggttcatctttagtagacattggatggcctgggtccgccaggctccagGggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactgggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5764 JY8QFUQ01BULWJ No results +5765 JY8QFUQ01A8LEY productive (see comment) Homsap IGHV3-48*01 F 1085 100.0 218/218 nt 99.54 217/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgatgtcgtggaactcag +5766 JY8QFUQ01C6GE7 unproductive Homsap IGHV1-8*01 F (see comment) 768 84.58 181/214 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [0.17.38.11] CARGSLDQGGLPQI#W out-of-frame + Low V-REGION identity (84,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cggatacaccttcagcagttatgatatcaactgggtgcgacaggccactggacgagggcctgaatggatggggtggatgagccctagcggtggtcatgcaaactatgcccagagattccagggcagaatcaccatgaccagggacacctccacaagcacagccttcttggaactaaacagcctgaaacttgaggatacagccatatattattgtgcgcgaggatccctcgaccaaggtggcctcccccaaattctggggccagggcaccctggtcaccgtctcttcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtccatcgcctgcctggtccagggcttcttcc +5767 JY8QFUQ01B9Z1X No results +5768 JY8QFUQ01A9ZDI productive (see comment) Homsap IGHV3-33*03 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5769 JY8QFUQ01DV2UQ No results +5770 JY8QFUQ01DQUUW unknown (see comment) Homsap IGHV3-74*03 F 126 54.81 74/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5771 JY8QFUQ01A8BUH unknown (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 673 79.81 170/213 nt 78.87 168/213 nt 8 7 X 8.7.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (79,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'AGG' (3 nucleotides at position 58 to 60 in the user submitted sequence), (do not cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 97 in the user submitted sequence), (do not cause frameshift) tctggattcagctttagcgattttgccatgagttgggtccgccaacctccagggaaaAGGgggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5772 JY8QFUQ01AR1IO No results +5773 JY8QFUQ01C83FO No results +5774 JY8QFUQ01AXV0U No results +5775 JY8QFUQ01A4GO0 No results +5776 JY8QFUQ01ANRW2 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 661 78.24 169/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (78,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5777 JY8QFUQ01BVAXI No results +5778 JY8QFUQ01CA0DL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1085 100.0 218/218 nt 98.62 215/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [2.16.37.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 90 of V-REGION: 1 nucleotides (from position 177 in the user submitted sequence), (cause frameshift) agcctctggattcaccGtttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5779 JY8QFUQ01B2ERL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARDGEWEMLDHW in-frame + ctccggattcaccttcagtaggtattggatgtattgggtccgccaagctccaggcaaggggctggtgtgggtctcacgcattaaaagtgatgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacatatttttgtgcaagagacggggagtgggagatgcttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +5780 JY8QFUQ01AW9L1 unproductive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ6*01 F (see comment) 94 61.29 38/62 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSGYYSTGY# out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ1*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5781 JY8QFUQ01BC0BC No results +5782 JY8QFUQ01A9MLL productive Homsap IGHV3-9*01 F 883 89.5 196/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CVKDRKGSNWYYFENW in-frame - gcctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5783 JY8QFUQ01DBXSG productive Homsap IGHV4-39*03 F 907 90.05 199/221 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-14*01 ORF 2 10 7 12 10.7.12 [2.17.38.11] CTREGPYYYGMDVW in-frame - tgctctggtgactccatcagtaatactgattactactgggtctggatccgccagaccccagggaagggactggagtggattgggagtatcgatttcagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccatagacacgtccgagaaccggttctccctgaggttgacctctatgaccgccgcagacacggccgtctattactgtacgagagagggaccctactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5784 JY8QFUQ01BMWXL No results +5785 JY8QFUQ01A96PZ No results +5786 JY8QFUQ01CQ0KE No results +5787 JY8QFUQ01A4D1L unproductive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 825 86.36 190/220 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 3 10 7 X 10.7.X [1.17.38.11] CARAGGWT#YFDSW out-of-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtggctccgtcaacagtggtaattactactggaactggatccgccaatccccagggaagggactggagtggattggatatatctactatgctggggccaccaacctcgccccctccctcaagaaccgagtcaccatatcgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccatatattactgtgcgagggccggtggctggacccctactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5788 JY8QFUQ01A1Z5H productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5789 JY8QFUQ01C1E8G No results +5790 JY8QFUQ01BECOA productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +5791 JY8QFUQ01AIS6M No results +5792 JY8QFUQ01ABZCV unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 977 94.5 206/218 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGRIVSVGMSGWF#PW out-of-frame - cctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgaccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5793 JY8QFUQ01DKDN0 No results +5794 JY8QFUQ01BWMN8 No results +5795 JY8QFUQ01A53DW unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 738 82.49 179/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 124 72.0 36/50 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [1.17.38.11] CARIWDSWSGAFDV## out-of-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtgggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +5796 JY8QFUQ01DLGU1 unproductive Homsap IGHV1-8*01 F 822 87.38 187/214 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [0.17.38.11] CARGRGYGSYADH## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tggatacagcttcagcaattatgatatcaactgggtgcggcaggccactggacaagggcttcagtggatggggtggatgaacccccacagtgccaatatcgtctacgcgcagaaatttcagggcagagtcaccatgaccagtgacgcctccataaccacagcctacatggaactgagcaacctgaaatctgacgacacggccgtgtattattgtgcgaggggccgagggtacggaagttacgctgaccactggggccagggaaccccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5797 JY8QFUQ01DABH5 No results +5798 JY8QFUQ01CP34G No results +5799 JY8QFUQ01DR4R2 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt 87.16 190/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); cctctggaGttcacgtttgacgactatgccatgagttgggtccgccaggctccagggaaggggccggagtCgggtctcaggtattattcctaatagtcgtgacagacactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagagcacagtgtatctgcaaatgaacaacctcagaggcgaggacacggccgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5800 JY8QFUQ01DKOBD No results +5801 JY8QFUQ01C5KXD No results +5802 JY8QFUQ01DESK4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 813 86.92 186/214 nt 85.51 183/214 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 7 12 8.7.12 [1.16.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 153 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaagggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtcgtggaactcag +5803 JY8QFUQ01CRF17 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 861 88.18 194/220 nt 87.73 193/220 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.16.38.11] CAKLGYIWDTGRAGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtgactccatcggcgatagtagtttctcatggggctggatccgccagccccagggaagggcctggagtggattgggagcatctattacagtgggggcacctattacaacccgtccctcgagagtcgagtcatcatgtccgtagacacgtccaggaatcagttctctctgagactgagtcttatgaccgccgcagacacggctctctattactgtgcgaaactgggctatatttgggataccgggcgcgcgggtgactactggggccatggaacactggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5804 JY8QFUQ01CCKX0 No results +5805 JY8QFUQ01C60D2 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5806 JY8QFUQ01CBYIA productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); cctcggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5807 JY8QFUQ01ADHKE No results +5808 JY8QFUQ01CUNSQ productive Homsap IGHV4-39*03 F, or Homsap IGHV4-39*07 F 919 91.28 199/218 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 10 7 12 10.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5809 JY8QFUQ01ADP3H unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +5810 JY8QFUQ01CKFOJ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 892 89.95 197/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +5811 JY8QFUQ01C3SL5 unproductive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-3*01 F 1 8 10 X 8.10.X [1.17.38.11] CITSFGGRSLAY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +5812 JY8QFUQ01C9SFZ unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 994 95.83 207/216 nt 94.91 205/216 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD6-6*01 F 3 8 8 X 8.8.X [1.17.37.11] CVRSEYSS#NWFDPW out-of-frame + in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 81 of V-REGION: 1 nucleotides (from position 147 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggCctggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcaccatctccagagcaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcacccccaacgatggacgtggtcgtcgcatgcctggtccagagcttcttccccca +5813 JY8QFUQ01AVKCR No results +5814 JY8QFUQ01BFOLT No results +5815 JY8QFUQ01BX4HY unknown (see comment) Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5816 JY8QFUQ01DR2NZ No results +5817 JY8QFUQ01CCRWD No results +5818 JY8QFUQ01B4SY2 unproductive (see comment) Homsap IGHV3-33*05 F (see comment) 742 82.87 179/216 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD5-12*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVKGTWIQ*LRPRLLG in-frame + stop codons Low V-REGION identity (82,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaagggacgtggatacaatgactacggcctcgactactgggggcccggggaaccctgctcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +5819 JY8QFUQ01CF0JA productive Homsap IGHV3-33*05 F 945 93.09 202/217 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD6-19*01 F 2 8 8 12 8.8.12 [1.17.38.11] CAKSRTAVPGDNPW in-frame + gtctggattcaccttcagtagctacggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaccagcctgagagccgcggacacggctgtttatcattgtgcgaaaagtaggacagcagtgcctggggacaacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5820 JY8QFUQ01BO84R unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 739 91.91 159/173 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found ctctggagtcacctttagtgactattggatgagctggatccgccaggctccagggaaggggccggagtgggtggccaacatagagcaagatgggagtgagataaattatgtggactctgtgaagggccgattcaccatctccagagacaacaccgagaatgcactgtatctgc +5821 JY8QFUQ01C83SA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +5822 JY8QFUQ01DNBZ9 No results +5823 JY8QFUQ01AN3XQ unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 921 90.58 202/223 nt 90.13 201/223 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 10 X 8.10.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); ctctggattcaccctcGaaaaacgcctggacgagctgggtccgccagggtccagggaaggggctggagtgggttggccgcattaagagcaaatctgaaggtggggcaatagactacgctgcacccgtgaagggcagatttaccatctcaagagatgattcagaagacacactgtttctgcaaatgaacagcctgagagccgaggacacagccgtgtattattgtgccacgcacggtggtccagggcttcttccccca +5824 JY8QFUQ01DNPP4 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 813 86.92 186/214 nt 85.51 183/214 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.16.38.11] CVRDSGPSGYARYESMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 75 in the user submitted sequence), (cause frameshift) ctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggcgtggagtggtctcacacgtaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5825 JY8QFUQ01CNHW0 No results +5826 JY8QFUQ01BAU8T unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +5827 JY8QFUQ01AJIXB productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 870 88.64 195/220 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 2 10 7 16 10.7.16 [1.17.38.11] CTNDRSMAVRATHAFHIW in-frame + ctctggtgactccattggtagcagtgcctactactggggctgggtccgccagccccccgggaaggggctggagtggattggaagtatctattatggtggcaacacctactacaacccgtccctcaggagtcgagtcagcatttccgcagacacgtccaagaaccagttctccctgcatctctactccgtgaccgccgcagacacggctctgtattactgtacgaatgaccgttcgatggccgttcgtgcaactcatgcttttcatatctggggcctagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +5828 JY8QFUQ01DA284 No results +5829 JY8QFUQ01ALBMO No results +5830 JY8QFUQ01BDT61 productive Homsap IGHV3-7*01 F 922 92.13 199/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame - tctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5831 JY8QFUQ01BQT4D No results +5832 JY8QFUQ01AAXJQ No results +5833 JY8QFUQ01BRVNG No results +5834 JY8QFUQ01DC45W unproductive (see comment) Homsap IGHV4-61*02 F 978 94.09 207/220 nt 93.18 205/220 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-10*01 F 1 10 7 X 10.7.X [1.17.38.11] CATVARRG##FDIW out-of-frame + stop codons in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 97 of V-REGION: 'T' (1 nucleotides at position 198 to 198 in the user submitted sequence), (cause frameshift); ctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggGggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccTgcagacacggccgtttattactgtgcgacagtggcgcgccggggggtcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +5835 JY8QFUQ01CE57J productive Homsap IGHV3-11*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame + ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggctttcatacattagtggtagtggaactaccatatactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +5836 JY8QFUQ01CMI9B No results +5837 JY8QFUQ01CITYD productive (see comment) Homsap IGHV3-11*01 F 909 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.37.11] CARRLLSSGWPPHEWGFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 158 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaagggactggagtgggtctcatatattagcagtactggtggttccatatattacgcagactctgtgaagggccgcttcaccacctccagggacaacaccaaaactcaatgtctctgcaaatgaacagcctgagcgtcgacgacacgggcgtctattattgcgcgagaaggcttctcagtagtggatggccaccccacgagtggggcttctggggccagggagtccaggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5838 JY8QFUQ01B3QTZ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 929 91.4 202/221 nt Homsap IGHJ5*02 F 205 88.24 45/51 nt Homsap IGHD3-3*01 F 2 10 7 11 10.7.11 [1.17.38.11] CARSYGFSRFDPW in-frame + tctctggtggctccatcaccagtagtctttaccgctggggctggatccgccagtccccagggaagggcctggagtggatagggaatatcttttatggtgggaccacctactacaacccgtccctcaagagtcgagtcaccttatccatagacacgtccaagagccagttctccctgaagctgtcctctgtgaccgccgcagacacggctctatattactgtgcgagatcgtacggtttctctcggttcgacccctggggccagggaaccctggtnaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5839 JY8QFUQ01B5VR4 productive Homsap IGHV1-24*01 F 970 95.31 203/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame + cggaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa +5840 JY8QFUQ01BZ5TN No results +5841 JY8QFUQ01B7QYW No results +5842 JY8QFUQ01CUX3B productive (see comment) Homsap IGHV3-NL1*01 F (see comment) 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CUX3B ; 8 AA in Homsap_IGHV3-NL1*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); tgtctggattcagtttcagtagcttttGgcatgcactgggtccgccaggctccaggcaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5843 JY8QFUQ01CZOQU productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 52 of V-REGION: 'AT' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift); tctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagATggggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5844 JY8QFUQ01DBGHI productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggatacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +5845 JY8QFUQ01APYE6 productive (see comment) Homsap IGHV3-69-1*02 P 925 92.96 198/213 nt 92.49 197/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-20*01 F 3 8 7 10 8.7.10 [2.16.38.11] CARDDKWAFDYW in-frame - Potentially, because of detected insertion/deletion however the closest V is a pseudogene in FR2-IMGT, from codon 55 of V-REGION: 3 nucleotides (from position 79 in the user submitted sequence), (do not cause frameshift) gtctctggattcaccttcagtgactacagcatgaactgggtccgccaggctccagggcaggggctggagtgggtctcatatagtcgcggaagaaccacatactacgcagactctgtgcagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgacagccgaggacacggctgtttattactgtgcgagagatgataagtgggcatttgactactggggccagggaaccctggtcgtcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +5846 JY8QFUQ01A89V5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + ctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +5847 JY8QFUQ01DW31H No results +5848 JY8QFUQ01C98AS productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5849 JY8QFUQ01AF98H No results +5850 JY8QFUQ01DIDF1 No results +5851 JY8QFUQ01CYQ4L unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 474 82.61 114/138 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (82,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc +5852 JY8QFUQ01BALAC productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 962 94.42 203/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.16.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 42 of V-REGION: 'C' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgGcactgggtCccgccaagctccagggaagggctggttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttcccccagga +5853 JY8QFUQ01DB2XW No results +5854 JY8QFUQ01DL8RT No results +5855 JY8QFUQ01BYP0E productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame + ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5856 JY8QFUQ01AWXY3 No results +5857 JY8QFUQ01B80XQ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttcccccag +5858 JY8QFUQ01BBPNM unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5859 JY8QFUQ01A2ANY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 829 86.76 190/219 nt 86.3 189/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [2.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGcctcgccgacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggttcagggcttcttccccca +5860 JY8QFUQ01AJH7W No results +5861 JY8QFUQ01BD95E unknown (see comment) Homsap IGHV2-5*03 F 177 54.69 105/192 nt 10 7 X 10.7.X [9.17.26.X] null - No rearrangement found gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5862 JY8QFUQ01CHRPW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-3*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKDVVMGFVAFDVW in-frame - atctggattcacctttaccaattttgccatgagctgggtccgccaggctccagggagggggctggagtgggtctcaggtattagtgctcgtggtagtagtgcgtactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactgtatctgcagatgaacagcctgagagccgaagacacggccgtatattattgtgtgaaagatgttgttatgggattcgttgcttttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5863 JY8QFUQ01AGTKS productive Homsap IGHV3-9*01 F (see comment) 769 84.26 182/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Low V-REGION identity (84,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggttaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5864 JY8QFUQ01A0F0Q No results +5865 JY8QFUQ01B0BQ5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 960 93.18 205/220 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - agcctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +5866 JY8QFUQ01CWRS4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa +5867 JY8QFUQ01C2NRC No results +5868 JY8QFUQ01BGB63 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 208 80.0 52/65 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggcttcttcccc +5869 JY8QFUQ01DSBTB No results +5870 JY8QFUQ01BCPR0 productive Homsap IGHV3-48*01 F 886 89.86 195/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARESTWEFTPDSW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcagtttcagtgactanagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagttctagtagtaccctatattatgcagactctgtgaagggccgattcaccgtctccagagacaatgacaagagttctctgtatctgcaaatgaccggcctgagagccgaagacacggcgacttattactgtgcgagagagtcgacgtgggaatttactcctgactcctggggcccggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +5871 JY8QFUQ01AMV2H productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaact +5872 JY8QFUQ01BWRLY unproductive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F (see comment) 741 81.25 182/224 nt Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 2 8 10 13 8.10.13 [1.17.38.11] CAITKNDVWGGADQ* in-frame - stop codons Low V-REGION identity (81,25% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctgggttcantttcagtggctcttctgttcactgggtccgccagacttccggaaaagggctggagtggattggccgtatcagaagtaaggcgaacgataacgcggcagtgtatcgtaagccgctgacgggcaggtttttcatctccagagatgattcacagagcacggcatatctgcaactgaacaacctgggagtcgacgacacggccacatattactgtgctatcactaaaaacgatgtttggggcggcgctgaccagtgaggccaggggaccctggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5873 JY8QFUQ01AT0CV productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 927 92.17 200/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5874 JY8QFUQ01BOE5N No results +5875 JY8QFUQ01AY7N1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.17 200/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGYHGPFDS## out-of-frame + ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacacatactactcagactccgtgaggggccggttcaccatctccagagacaacgccaagaacacgatgtatctgcaaatgaacaccctgagagacgaggacacggccgtctatttctgcgcgaaaggttaccacggcccctttgactcttggggccggggcaaccctggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +5876 JY8QFUQ01ACLRQ productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 2 9 7 11 9.7.11 [1.17.38.11] CARASTLRYLDRW in-frame - tctctggtggctccatcagcagtgataattggtggagttgggtccgccagcccccagggaagggactggaatggattggggaaatatatcatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacaagtccaagagtcaattcttcctggagctgaggtctgtgaccgccgcggacacggccgtatattattgtgcgagagcctccacactacgatatcttgaccgctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +5877 JY8QFUQ01C9TC2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagGggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +5878 JY8QFUQ01B5XB0 No results +5879 JY8QFUQ01CAJHT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5880 JY8QFUQ01A7ZVA unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 930 91.03 203/223 nt Homsap IGHJ4*03 F (see comment) 78 62.5 30/48 nt Homsap IGHD3-22*01 F 3 8 10 X 8.10.X [1.17.38.11] CATDRPYYKNRCWPTLVLLRYGRFG# out-of-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) ctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaatcgctgctggccgactctggtattactacggtatggacgttttgggggcccaaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5881 JY8QFUQ01CVKEH unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 994 95.83 207/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5882 JY8QFUQ01B1JFN unproductive Homsap IGHV4-59*02 F 894 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD1-26*01 F 1 8 7 X 8.7.X [1.17.38.11] CARGGSGGAYWNLIRG#W out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'GAT' (3 nucleotides at position 20 to 22 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'TACGATCCCTCC' (12 nucleotides at position 107 to 118 in the user submitted sequence), (do not cause frameshift); ctctggtggctccgtcagaGATttttattactggagttgggtccggcagcccccagggaagggactggagtggcttggatatctctattacagagggagcaccaagTACGATCCCTCCtataatccctccctcgagagtcgagtcaccatttcagttgacccgtccaagaaccagttctccctgaagctaaactctgtgaccgctgcggacacggccgtgtattactgcgcgagaggtgggtccggtggggcctactggaatctgatccggggactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +5883 JY8QFUQ01ARNEJ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 798 85.0 187/220 nt 83.64 184/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 9 7 16 9.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'GACTC' (5 nucleotides at position 26 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 31 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) tctctggtgactcccatcgagtagtGACTCagttactattggtgctggatccggcagGcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5884 JY8QFUQ01DUSX9 unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5885 JY8QFUQ01AZ8E6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5886 JY8QFUQ01CD1AQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5887 JY8QFUQ01CVGTZ productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 935 93.02 200/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - tctctggattcaccgtcaatagaaactacatgagttgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcacccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5888 JY8QFUQ01DPOAQ No results +5889 JY8QFUQ01CYEFE productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 897 90.0 198/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtctcgcctgcctggtccag +5890 JY8QFUQ01B5OHS No results +5891 JY8QFUQ01B8DGT No results +5892 JY8QFUQ01CBY02 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 136 64.86 48/74 nt 8 X X 8.X.X [1.15.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgt +5893 JY8QFUQ01DVFXJ productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 718 82.16 175/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDWGGSFDRYYFDYW in-frame - Low V-REGION identity (82,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release caccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5894 JY8QFUQ01BWFKV productive Homsap IGHV1-3*01 F 956 94.81 201/212 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 7 8 9 7.8.9 [X.17.38.11] CARWNNDLDYW in-frame + gatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5895 JY8QFUQ01DSDAK unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 947 92.31 204/221 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [2.17.38.11] CARGASIARLRYGRL# out-of-frame - cagcctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagaggggcctcgatcgcgcggctacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5896 JY8QFUQ01DJCMC No results +5897 JY8QFUQ01CSGJC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5898 JY8QFUQ01DW1EC No results +5899 JY8QFUQ01DC0FC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 928 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 79 to 81 in the user submitted sequence), (do not cause frameshift); gcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5900 JY8QFUQ01B6UPU No results +5901 JY8QFUQ01C5NZ5 productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKEEFDTGWTQPGDW in-frame + ctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5902 JY8QFUQ01C9EYH No results +5903 JY8QFUQ01DLA1D productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1030 97.69 211/216 nt 97.22 210/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5904 JY8QFUQ01CSA2T unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5905 JY8QFUQ01DINCJ productive (see comment) Homsap IGHV3-13*01 F 903 91.59 196/214 nt 91.12 195/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD4-11*01 ORF 3 8 7 17 8.7.17 [1.17.38.11] CAREVTRLTVPYYLYFDLW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 97 of V-REGION: 'G' (1 nucleotides at position 191 to 191 in the user submitted sequence), (cause frameshift); ctctggaatcaccttcagtgactccgacatgcactgggtccgccaagctccaggagaaggtctggagtgggtcgcagctattggaactgctggtgatacatactatgcagactccgtgaagggccgattctccattaccagagagaatgccaagaactccttgtttcttcaaatgaacagcctgagagccGggggacacggctgtttattattgtgcaagagaggtgactagacttactgtcccctattacttatacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatcctcgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc +5906 JY8QFUQ01C3Y8K No results +5907 JY8QFUQ01CX5BS unproductive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F (see comment) 559 73.06 160/219 nt 70.78 155/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null - stop codons no junction found Low V-REGION identity (73,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 45 of V-REGION: 'TT' (2 nucleotides at position 52 to 53 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'TGGCA' (5 nucleotides at position 105 to 109 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 91 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) ttcggagacgatatatctggagacagtgttacttggaactggatcaggcagTTcccccagggaagGgggcttgagtggctcgggcgtatcttcacaggtctgagTGGCAtaccgactacttggcgtctgttagaggccgaatctccatggatgtcgacacgtccaagaaccacttcaccctgcagctccgctctctgactcccgacgacacggctacatatttctgtacaagaggctctctaactgggacatatccttctgaccactggggtctgggggacccccagtgaccgtctcctcacatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5908 JY8QFUQ01CQZHV productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +5909 JY8QFUQ01BXCIA unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ6*01 F (see comment) 94 61.29 38/62 nt Homsap IGHD5-24*01 ORF 3 8 7 X 8.7.X [1.17.38.11] CARAPRTATLLDP# out-of-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5910 JY8QFUQ01A0GUH unproductive Homsap IGHV3-72*01 F 1069 98.2 218/222 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYD#PG out-of-frame + tctggattaaccctcagtgaccactacatggactgggcccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5911 JY8QFUQ01DPQLN unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 160 80.0 40/50 nt Homsap IGHD6-25*01 F 3 8 7 X 8.7.X [1.17.38.11] CARGTRYNNGLD#FDVW out-of-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgctttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5912 JY8QFUQ01A4GYO No results +5913 JY8QFUQ01BA0WX No results +5914 JY8QFUQ01BUNHA No results +5915 JY8QFUQ01BBFFD unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 259 59.28 115/194 nt 8 8 X 8.8.X [1.17.30.X] null - No rearrangement found Low V-REGION identity (59,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5916 JY8QFUQ01BA86Z productive (see comment) Homsap IGHV3-11*01 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDGDADYGDLPIPFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctctgaattcagtttcactgaccaccacatgagctggatccgccgggctccagggaaggggctggagtgggtgtcatacattagtcctaCagggtagtgccatattttacgcagactctgtgaaggcccgtttcaccatctctagggacaacgccaagaatttactatatctacaaatgaacagcctgagacccgaggacacggccatctattactgtgcgagagatggggacgcggactacggtgacttgcccatccctttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +5917 JY8QFUQ01BVCVS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKLENSSGNEDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctgaattaacgtttgatatatatgccatgacttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactggtagtggtgataatgcctactacgcagacttcgtgaagggccgattcgccatctccagagacaattccaagaacatgttgtatttgcaaatgaacaacctgcgaggcgaggacacggccgtttattactgtgcgaaactggaaaatagcagtgggaatgaagactcctggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5918 JY8QFUQ01BLMSE No results +5919 JY8QFUQ01BJ6Y5 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [1.17.38.11] CTRGRSDAWELSDHW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 98 of V-REGION: 'G' (1 nucleotides at position 195 to 195 in the user submitted sequence), (cause frameshift); tcgacgatgggtcctgcagaaactgcttctggagttggatccgccagtccccagggaaggggctggagtggattgggaaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagtcgagtcaccatatcattagacacgtccaacaaccaagtctccctgaggttgagctctgtgaccgccgcgGgacacggctgtgtattattgtacgcgagggcgatccgacgcgtgggaattatcggaccactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5920 JY8QFUQ01BU1B8 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5921 JY8QFUQ01DV5O6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CGKPIVGATGREMPVSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagcaactatgccatgaactgggtccgccagggttccagggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5922 JY8QFUQ01DTPYP unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 718 80.18 178/222 nt 79.73 177/222 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 10 X 8.10.X [1.17.37.X] null + Rearranged sequence but no junction found Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 161 in the user submitted sequence), (cause frameshift) ctctggattcactgtcaataacgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgatggcgggacagcagactacgctccatttgtggacgacagattcaccatttcaacagatgattcaaaaacacgttgtatctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5923 JY8QFUQ01A9BT1 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 103 52.99 71/134 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcatgcctggtccagggcttcttccccca +5924 JY8QFUQ01CB275 productive (see comment) Homsap IGHV2-5*02 F 1165 97.94 238/243 nt 97.53 237/243 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 2 10 7 11 10.7.11 [9.16.38.11] CAHRRIRFGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) gaccctcacgctgacctgcaccttctctgggttctcactcagcactggtggagtgggtgtgggctggatccgtcagccccaggaaaggccctggagtggcttgcactcatttattgggatgatgataagcgctacagcccatctctgaagagcagactcaccatcaccaaggacacgtccaagaaccaggtggtcctcacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacaggaggatacgattcggctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc +5925 JY8QFUQ01DLCHK No results +5926 JY8QFUQ01AYBH3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgg +5927 JY8QFUQ01A98PX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5928 JY8QFUQ01BBLIL productive (see comment) Homsap IGHV3-7*01 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame + Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 54 of V-REGION: 'AGG' (3 nucleotides at position 74 to 76 in the user submitted sequence), (do not cause frameshift); ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggaggggctgggagtgggtcAGGccaagcataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggctt +5929 JY8QFUQ01DH8HE productive (see comment) Homsap IGHV3-48*02 F 868 88.89 192/216 nt 87.04 188/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 3 8 8 10 8.8.10 [1.17.38.11] CASGGVTEAHYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 56 to 57 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); tctggattcagctccagtgaatataccatgaactgGggtccgccaggctccagggGAagggggctggagtgGggtttcatacattggtgttggtactggtggcatatactacgcagactctgtgaGggggccgattcaccatctccagggacaatgccgagaactcagtgcatctgcaaatgaacagcctgagagacgacgacacgggtgtttattactgcgcgagcggaggggtgacagaggctcactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5930 JY8QFUQ01C4FJ1 No results +5931 JY8QFUQ01BMUI4 No results +5932 JY8QFUQ01BK9M6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagg +5933 JY8QFUQ01B9DTH No results +5934 JY8QFUQ01DB2CL unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5935 JY8QFUQ01C966Y productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGYW in-frame + ctctggattcagctttagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaaatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtttttgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgattagtagtgatttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5936 JY8QFUQ01ATBFG unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 293 89.04 65/73 nt 8 X X 8.X.X [1.15.X.X] null + No rearrangement found ctctgggttcaccatcactcactactccatggcctgggtccgccaggctccggggaaggggctggagtgggtc +5937 JY8QFUQ01CZFFV No results +5938 JY8QFUQ01C5NFT productive (see comment) Homsap IGHV3-30*01 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 7 11 8.7.11 [1.17.38.11] CACGHMRDGYDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +5939 JY8QFUQ01C3FY7 productive Homsap IGHV3-48*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDQSPGVAVAGPDYW in-frame + ctctggattcaccttcagtagatatagtatgaactgggtccgccaggctccaggaaaggggctggagtgggttgcatacattagaagtagcagtagtgtcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcaaagtccgggtgtagcagtggctggtcctgattactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaangtggtcgtcgcatgcctggtccagggcttcttcccc +5940 JY8QFUQ01CCRR3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +5941 JY8QFUQ01AOQZO productive (see comment) Homsap IGHV4-61*02 F 857 87.78 194/221 nt 87.33 193/221 nt Homsap IGHJ4*03 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARERSASMGAARELDSW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'GGG' (3 nucleotides at position 99 to 101 in the user submitted sequence), (do not cause frameshift); tctctggtggccccatcggcagtggtgcctactactggacctggatccggcagcccgccgggaagggattggagtggctcgggcgtgtttatagtggtGGGgggatcatcaattacagtccctccctcaagagtcgaatcaccatgtcgatagacacgtccaagaaccagttctccctgaagttgacctctgtgaccgccgcagacacggccttatattactgtgcgagagaacgtagtgcctcgatgggcgctgcgagagaacttgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +5942 JY8QFUQ01BSBQN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame + ctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +5943 JY8QFUQ01A4X69 productive Homsap IGHV1-3*01 F 966 94.86 203/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARWNNDLDYW in-frame - tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5944 JY8QFUQ01A1CLZ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 71 of V-REGION: 'CA' (2 nucleotides at position 123 to 124 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtcccCAtcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5945 JY8QFUQ01A26P2 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 119 54.62 71/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +5946 JY8QFUQ01CA9TH unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 99 52.59 71/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5947 JY8QFUQ01CZI41 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 892 89.95 197/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5948 JY8QFUQ01C8531 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt 90.78 197/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 7 8 13 7.8.13 [2.17.38.11] CVRSEYSSSNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift)in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 23 in the user submitted sequence), (cause frameshift) gcctccggattcaccttagtagttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5949 JY8QFUQ01B4L0R productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTRQTGNYYYFGVDVW in-frame - cctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5950 JY8QFUQ01BFW88 productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + ctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5951 JY8QFUQ01B7Z4J unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 160 80.0 40/50 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRRGMVAGRYD#FDIW out-of-frame - ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgctttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5952 JY8QFUQ01DDD2K productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1016 97.21 209/215 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [0.17.38.11] CARLHGYCGGGYCYDWYFDLW in-frame - tggagtacagctttaccagctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgattccagatacagcccgtccttccaaggccaggtcaccatttcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgagactccatgggtattgtggtggtggttattgctacgactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5953 JY8QFUQ01BERKI productive Homsap IGHV3-72*01 F 921 90.58 202/223 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-8*02 F 2 8 10 17 8.10.17 [1.17.38.11] CTRDTTDTGGQSFNGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggtttccccttcagtgaccacttcatggactgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctggggccaggggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5954 JY8QFUQ01BNF0N unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + tctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +5955 JY8QFUQ01BDD24 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD2-21*01 F 3 8 8 12 8.8.12 [1.17.37.11] CARGKMVSTGMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 190 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagcagctactggatgcactgggtccgccaagctccaggggaggggctggtgtgggtcgctcggatcaaaagtgatgggagtagcacaagctacgcgggctccgtgaggcgccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagcctgaggccgaggacacggccgtgtattactgtgcgcgagggaagatggtgagcaccggtatggacgtctggggccaagggaccacggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +5956 JY8QFUQ01AR5RU unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5957 JY8QFUQ01A5935 productive Homsap IGHV4-61*02 F 875 88.69 196/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + tctctggtggccccatcagcagcagcacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatcccgacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttcccc +5958 JY8QFUQ01AV6PF productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5959 JY8QFUQ01CF2PW unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.74 200/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*02 F 3 8 8 X 8.8.X [1.17.38.11] CAKKYHYGSGLTCT#FDYW out-of-frame - stop codons cctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcgggacttacttgtactatttgactactggggccagggaaccctggtcaccgtctcctcagcattcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5960 JY8QFUQ01BXZYZ productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaacctcag +5961 JY8QFUQ01B3GE2 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtGactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5962 JY8QFUQ01DXE4S unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 1 8 7 X 8.7.X [1.17.38.11] CARADNYDSLGLKFDP# out-of-frame + tctctggtgactccatcagtagtaactactggaactggatccggcagcccccagggaagggactggagtggattgggtatatctatcacagtgggagcaccagctacaacccctccctcaggagtcgagtcaccatatcattagacacgtccaagaaccagttctccctgaaactgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggcggataattatgatagtcttgggctgaagttcgacccctgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcattgcctgcctggtccagggcttcttcccc +5963 JY8QFUQ01AJNP6 No results +5964 JY8QFUQ01AS47P unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 804 86.45 185/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CGTSSRAWGADAFDI## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctgggctcagcgtcagtaactaccgcatgggctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagagatgatagtacagatcatgtagattccgtgaagggccgattcaccgtttcccgagacaattccaagaacacattgtaccttcagatgaacagtgtgacagccgaggacacggccgtttattattgtggaactagttcccgcgcctggggcgctgatgcctttgatatctggggcccaggggacactggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5965 JY8QFUQ01CZ4CX No results +5966 JY8QFUQ01BLB0H productive (see comment) Homsap IGHV4-61*02 F (see comment) 590 74.77 163/218 nt 73.85 161/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-10*01 F 3 10 7 16 10.7.16 [1.16.38.11] CARECSNSKVGPRALDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (74,77% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 102 of V-REGION: 'A' (1 nucleotides at position 212 to 212 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) tctggtggcccgatcaaaagtcctgattaccattggacgtggatccggcagccgccgggaagggactggagtgggtcggacgtgtctatatgactggttatgtcgaccacaatccatccctctccgggcgtctcaccatgtctatcgacacctcgaagaatcaattttctatgacattgacctctgtgaccgccgcagacacggccctataAtttttgtgcgagggagtgtagtaattcgaaggtcggaccgagagcgcttgattcctggggcccgggaagtctggtcaccgtatcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5967 JY8QFUQ01BESQ8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [2.17.38.11] CAKEGNLGYFDDW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) gcctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5968 JY8QFUQ01AH819 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 152 94.12 32/34 nt 91.18 31/34 nt 7 X X 7.X.X [1.2.X.X] null - No rearrangement found in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) ctctggattcacctttagcaacttgccatgacct +5969 JY8QFUQ01CFXXJ No results +5970 JY8QFUQ01AQTOB No results +5971 JY8QFUQ01B3C3I No results +5972 JY8QFUQ01BWSCG No results +5973 JY8QFUQ01DOWAN No results +5974 JY8QFUQ01C6KQ4 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 976 94.91 205/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.37.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 131 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggGggctggtgtgggtctcacgtgttaatggtgatCgggggtaggacagcctacgcggactccgtgaagggccgatcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5975 JY8QFUQ01CM68L productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5976 JY8QFUQ01BFIW3 unknown (see comment) Homsap IGHV3-49*01 F, or Homsap IGHV3-49*03 F or Homsap IGHV3-49*05 F 88 51.91 68/131 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons ttctggattcacctttggtgactatgctatgagctggttccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +5977 JY8QFUQ01CJ8XP unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CARAYSGPGPYYFD#IG out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattgggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +5978 JY8QFUQ01CZS6L No results +5979 JY8QFUQ01CHLUK unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARKGPRRDGSLQQCDMDV## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggacccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5980 JY8QFUQ01CHJGG No results +5981 JY8QFUQ01CG9T4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 783 84.79 184/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-15*01 F 3 8 8 12 8.8.12 [1.17.38.11] CATGARGLGASDYW in-frame - Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggaatcacctttagcgcctatgacatgacctgggtccgccagactccagggaagggtctggagtgggtctcatccattggttcatttggtgatgacacgcactacttagactccgtgaggggccggttcaccatctccagagacaattccaacgacacgatgtatctgcaaatgctcagcctgagagtcgaggatacggccacttattactgtgcgacaggggcacgggggctcggtgcgagtgactactggggccagggaacacaggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +5982 JY8QFUQ01AKHQ3 No results +5983 JY8QFUQ01DTA3Y No results +5984 JY8QFUQ01AS13P productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 918 91.71 199/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKAGRGLIRPNNWFDPW in-frame + ctctggatttaccttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcggggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5985 JY8QFUQ01CFVCE unproductive Homsap IGHV4-39*02 F (see comment) 906 92.42 195/211 nt 91.94 194/211 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 10 5 X 10.5.X [1.16.38.11] CARPPHGSYCP#FDYW out-of-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (5 AA in JY8QFUQ01CFVCE ; 7 AA in Homsap_IGHV4-39*02) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 55 of V-REGION: 9 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggtgtctccatcagcagtggtcgttactactggggctggatccgccagcccccagggaaggggctggagtggattggacttagtgggagctccaacctcaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccacttctccttgaaactcaactctgtgaccgccacagacacggctgtatattactgtgctagacccccccatgggagttactgcccccttcgactactggggccagggaatcctggtgaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +5986 JY8QFUQ01CLW7C productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame - ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5987 JY8QFUQ01DCXWB productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 869 88.99 194/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CTRELRMAAARDGVDIW in-frame - ctctgggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccacctccagagacaattctaagaacatcttggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggatggctgcggcgcgtgatggtgttgacatctggggccaaggcacaatggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +5988 JY8QFUQ01A3O34 No results +5989 JY8QFUQ01CG0B3 No results +5990 JY8QFUQ01CC481 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 904 91.2 197/216 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame - tccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +5991 JY8QFUQ01A6DQI No results +5992 JY8QFUQ01CO7ZE productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 872 89.77 193/215 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + tatatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaatagtcgagtcatcatatcgatagacacgtccaagaaccaggtctccctgaagctcttctctgtgaccgccgcggacacgggtgtgtactattgtgcgaggcccacgtatagtagcggccgggacgcctttgatacctggggccaagggacgacggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +5993 JY8QFUQ01CPG09 No results +5994 JY8QFUQ01DOMLT productive (see comment) Homsap IGHV3-7*03 F 573 90.65 126/139 nt 89.93 125/139 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 X 19 8.X.19 [1.15.22.11] CARDRYSSDSSYYMPNWLDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 78 nucleotides (from position 74 in the user submitted sequence), (do not cause frameshift) ctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5995 JY8QFUQ01C6HJC No results +5996 JY8QFUQ01ACI1B unknown (see comment) Homsap IGHV3-64*02 F (see comment) 630 76.85 166/216 nt 8 8 X 8.8.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (76,85% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +5997 JY8QFUQ01B2V0H unproductive Homsap IGHV1-2*02 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ4*01 F 109 68.75 33/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [0.16.38.11] CARDGISMTLVRGVRPXDY# out-of-frame - in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) ctggatacaccttcatcggccattatatacattgggtgcgacaggccctggacaagggcttgaatgggtggggtggatcaaccctaacagtggtgttacaaactatgcacagcagtttcaggacagggtcaccatgaccgtcgacacgtccatcagcactgcctacatggacctcaaaagtctaaagtctgacgacacggccatctattactgtgcgagagacggaataagtatgactctggttcggggagttaggcccttngactactggggccaggaaccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +5998 JY8QFUQ01C4GHR productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt 90.91 200/220 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtgataatttctactggggctggatccgccagccCcccagggaagggactgcagtggattgGggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +5999 JY8QFUQ01BMVUA No results +6000 JY8QFUQ01DA5JD unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + stop codons ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgtaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca +6001 JY8QFUQ01A07SP No results +6002 JY8QFUQ01APX85 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctccggattcacctttagtagttactggatgcactgggtccgccaagctccagGgggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +6003 JY8QFUQ01AG0BX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtctcccctcggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6004 JY8QFUQ01BJGET unproductive (see comment) Homsap IGHV1-18*01 F 849 88.79 190/214 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*02 F 1 8 8 X 8.8.X [0.17.38.11] CARDGYCSTKNCFAKTDFVWGP*#YW out-of-frame + stop codons tggttacagttttaccaattatggtattagctgggcgcgacaggcccctggacaagggcttgagtggatgggatggatcagcacattcaatgatgtcacataccttgcacagaagttccagggcagagtcaccatgaccactgacacctccacgagcacagcctacttggaactgaggagcctgacatctgacgacacggccgtttatttttgtgcgagagacggatattgtagtacgaagaattgcttcgccaagaccgacttcgtttggggaccataaactactggggccagggatccctggtcgccgtctcttcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +6005 JY8QFUQ01CI94Y productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaTggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccagttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6006 JY8QFUQ01CIZXQ No results +6007 JY8QFUQ01DB6Y7 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 91 58.11 43/74 nt 8 X X 8.X.X [2.14.X.X] null - No rearrangement found gcctctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6008 JY8QFUQ01AR3VS No results +6009 JY8QFUQ01CC6TQ unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 129 62.82 49/78 nt 8 X X 8.X.X [1.17.X.X] null + No rearrangement found tctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6010 JY8QFUQ01DL4ZH No results +6011 JY8QFUQ01C6H8W productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARFGPLTRPDYWG in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccaggggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6012 JY8QFUQ01DW4N9 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 904 91.2 197/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'GCTGGGA' (7 nucleotides at position 62 to 68 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 75 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggGCTGGGAgtggggtcagtctgggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6013 JY8QFUQ01DS8TN unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-48*01 F 950 93.12 203/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDRITIFSYNW#FDPW out-of-frame + cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggtttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6014 JY8QFUQ01DQG0K unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 106 55.77 58/104 nt 8 8 X 8.8.X [1.17.X.X] null + No rearrangement found stop codons ctctggattcaccttcagtcgttatagcatgaactgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6015 JY8QFUQ01BYF1A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccctggggctgcctggtcaagggactacttgcccccgaaccggtgacggtgtcgtggaactc +6016 JY8QFUQ01BBG0J No results +6017 JY8QFUQ01ATBZH No results +6018 JY8QFUQ01CWLFI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKGIVGASMQADWFHPW in-frame - cctctggattcgtctttggcgactatgcgatgagctgggtccggcaggctccagggagggggctggagtgggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6019 JY8QFUQ01BIYSS No results +6020 JY8QFUQ01CU3GV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6021 JY8QFUQ01BRNFF productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 2 9 7 11 9.7.11 [1.17.38.11] CARASTLRYLDRW in-frame + ctctggtggctccatcagcagtgataattggtggagttgggtccgccagcccccagggaagggactggaatggattggggaaatatatcatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacaagtccaagagtcaattcttcctggagctgaggtctgtgaccgccgcggacacggccgtatattattgtgcgagagcctccacactacgatatcttgaccgctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccgaaggtcttcccgctgagcctctgcagcacccanccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +6022 JY8QFUQ01CJRQU No results +6023 JY8QFUQ01CJ6OW No results +6024 JY8QFUQ01AM18K unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +6025 JY8QFUQ01BM4YY productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 909 91.24 198/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKVSGNSRTYWYLDIW in-frame + ttctggatacaactttcccagatattggatcgcctgggtgcgccagattcccgggagaggcctggagtgggtggggatgatctatcctggtgactctgagaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacgcgtccatgaacaccgcctacctgcagtggagcagcctgaaggcctccgacaccgccatatacttctgtgcgaaggtctctggtaactctcgaacctactggtacctcgatatctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +6026 JY8QFUQ01AYKK2 No results +6027 JY8QFUQ01AJ3M6 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARDRRGYSYEMDYW in-frame - ctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6028 JY8QFUQ01B401Y unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 92 90.91 20/22 nt 6 X X 6.X.X [1.X.X.X] null + No rearrangement found ctctggattaaccctcagtgac +6029 JY8QFUQ01CEXWC productive Homsap IGHV3-66*02 F (see comment) 759 84.11 180/214 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-21*01 F 3 8 7 11 8.7.11 [1.17.38.11] CARHLMVYALDVW in-frame + Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaggggctggagtgggtctcagtcttatttagtactggcactgcatactacgcagactccgtgaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6030 JY8QFUQ01BXTW5 productive Homsap IGHV3-7*01 F 882 89.86 195/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +6031 JY8QFUQ01DQWNK No results +6032 JY8QFUQ01AXYJ6 unproductive (see comment) Homsap IGHV4-39*03 F 923 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 1 9 7 X 9.7.X [1.17.38.11] CARSITLTVVVMND##FDVW out-of-frame - stop codons in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) tccggtggctccatcaacagtagaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgccttttgatgtctggggccaagggacattggtcaccgtctccttagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6033 JY8QFUQ01B6ES1 productive Homsap IGHV3-48*01 F 1085 99.54 217/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASIFGVVPLGNYYYGMDVW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc +6034 JY8QFUQ01DMIV2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6035 JY8QFUQ01BE13M No results +6036 JY8QFUQ01C30YK productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 38 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtgtccatagcatgaactggtccgccaggctccaggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccctctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6037 JY8QFUQ01CFSGR productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); ctctggattcaccttcgGggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6038 JY8QFUQ01AVBLL productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1035 97.7 212/217 nt Homsap IGHJ3*02 F 88 64.0 32/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame + gtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +6039 JY8QFUQ01CWSFH unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1007 96.74 208/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CAREDGFRQT##FDYW out-of-frame + stop codons tctctggtggctccatcagtagttactactggagctggatccggcagcccccaggaaagggactggagtggattgggtatatcttttacactgggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggttccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6040 JY8QFUQ01A52Y0 unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6041 JY8QFUQ01CS07U productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaTggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6042 JY8QFUQ01DAU99 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame - tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6043 JY8QFUQ01CUYR1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6044 JY8QFUQ01B8DY9 No results +6045 JY8QFUQ01CO5QN productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 940 93.06 201/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 15 8.8.15 [2.16.38.11] CAKEQEPHGHYVGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 56 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) gcgtctggattcaccttcagtagctacggcatgcactgggtccgccaggctccagcaagggctggagtggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggccgtgtattcctgtgcgaaagaacaagaaccacatgggcattatgttggaactgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6046 JY8QFUQ01CD20L No results +6047 JY8QFUQ01AU91D No results +6048 JY8QFUQ01BPDC6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-21*02 F 2 8 8 16 8.8.16 [2.17.38.11] CAKSECRDCYPKNYLDYW in-frame - gcctctggattcacctttacctactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtggtgttggtaacacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgggagccgacgacacggccgtatattactgtgcgaaatcggagtgtcgtgactgctaccctaagaactaccttgactactggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6049 JY8QFUQ01DNT81 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 7 8 12 7.8.12 [2.17.38.11] CARADDYGDYPEFW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) gcctcaggatcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6050 JY8QFUQ01AL9P8 No results +6051 JY8QFUQ01CWDG3 No results +6052 JY8QFUQ01A6DSA productive (see comment) Homsap IGHV3-48*01 F (see comment) 759 84.11 180/214 nt 83.18 178/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaAaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6053 JY8QFUQ01C46L0 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 912 92.06 197/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [0.17.38.11] CARLGQLALDYW in-frame + tggatacagctttaccaattactggatcggctgggtgcgccaggtgcccggaaaaggcctggagtggatggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6054 JY8QFUQ01BU4ML No results +6055 JY8QFUQ01A9RMF productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 871 89.72 192/214 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccntgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6056 JY8QFUQ01DBBYU No results +6057 JY8QFUQ01CUSQF productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt 99.55 219/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6058 JY8QFUQ01AOAW9 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 113 67.27 37/55 nt 8 X X 8.X.X [1.9.X.X] null + No rearrangement found ctccggattcacctttagtagtttctggatgcactgggtccagggcttcttcccc +6059 JY8QFUQ01BQ6JD unproductive (see comment) Homsap IGHV3-7*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [0.17.37.11] CARVGYGYRGIYF#FDYW out-of-frame - stop codons in FR3-IMGT, from codon 96 of V-REGION: 1 nucleotides (from position 191 in the user submitted sequence), (cause frameshift) ctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagcgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttcctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6060 JY8QFUQ01CKPJN productive Homsap IGHV3-9*01 F 990 95.39 207/217 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CAKEGNLGYFDDW in-frame + ctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtggatctcaggtattagctggaatagtggtagtatagggtatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6061 JY8QFUQ01AZJDB unproductive Homsap IGHV3-7*01 F 1032 96.82 213/220 nt 96.36 212/220 nt Homsap IGHJ6*01 F (see comment) 148 70.97 44/62 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [2.17.38.11] CAISSGFTRRA#W out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGcctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggttttactcgacgggctactggcggcgaaggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6062 JY8QFUQ01DL8G0 No results +6063 JY8QFUQ01B6Y53 productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6064 JY8QFUQ01C3OQP productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F (see comment) 793 84.93 186/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 3 10 7 11 10.7.11 [1.17.38.11] CAGGEDPFKVRHW in-frame - Low V-REGION identity (84,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggtggctccttttctaatcatggttaccactgtagttggctccgccagttcccagggaaggacctggagtggattgcctacatctattacactgggagcaccgagtataacccgtccctcaggagtcgagttgccatatcagtggacacgtctgggaaccagtgttccctggagttgaactctgtgagtgccgcggacacggccgtctattactgtgcgggaggcgaggatcccttcaaagttcgacactggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6065 JY8QFUQ01DC9NI unproductive Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDGPPYLYGSHGNSFDQ## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggcccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6066 JY8QFUQ01ADMF5 No results +6067 JY8QFUQ01A3ATB unknown (see comment) Homsap IGHV3-13*02 F, or Homsap IGHV3-16*01 ORF or Homsap IGHV3-16*02 ORF or Homsap IGHV3-19*01 P or Homsap IGHV3-35*01 ORF 105 100.0 21/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattcaccttcagtaa +6068 JY8QFUQ01BH9IY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 926 92.56 199/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 7 8 13 7.8.13 [1.16.38.11] CAKGYSSGWYDFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtagtttgccatgacctggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6069 JY8QFUQ01BA4FL productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 816 85.91 189/220 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 10 7 12 10.7.12 [1.17.38.11] CARAGGWTPYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtggctccgtcaacagtggtaattactactggaactggatccgccaatccccagggaagggactggagtggattggatatatctactatgctggggccaccaacctcgcctcctccctcaagaaccgagtcaccatatcgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccatatattactgtgcgagggccggtggctggaccccctactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6070 JY8QFUQ01CVRND productive (see comment) Homsap IGHV3-33*05 F (see comment) 762 83.18 183/220 nt 82.73 182/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.17.38.11] CVKGRGYNDYGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); agcgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatAttaatgaaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6071 JY8QFUQ01DHLX1 No results +6072 JY8QFUQ01DG2P7 productive (see comment) Homsap IGHV1-3*01 F 956 94.81 201/212 nt 94.34 200/212 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 7 9 8.7.9 [0.17.38.11] CARWNNDLDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 2 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6073 JY8QFUQ01A32WM productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 8 13 8.8.13 [1.17.38.11] CATYGRFSFSPLDYW in-frame + gtctggattcgacttcagtagttatggcttccattgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctccccttgactactggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6074 JY8QFUQ01AD2CD No results +6075 JY8QFUQ01AMAA3 unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYFGTL#DYW out-of-frame + stop codons ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttggaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6076 JY8QFUQ01B5PFC No results +6077 JY8QFUQ01BTTXT unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 79 62.0 31/50 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDDGGHMTLDV## out-of-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggcccaagggacaatggtcagcgtctctccggcctccaccaagggcccaatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcanttccccagaccggtgacggtgtgcgtggaactcag +6078 JY8QFUQ01BEU1H productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6079 JY8QFUQ01A5TJ6 unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccactaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +6080 JY8QFUQ01AOBK0 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 774 83.87 182/217 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [1.17.38.11] XVRGPF*CQLVWQ#WFDPW out-of-frame + stop codons Low V-REGION identity (83,87% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcatcttcggcaactattggatgcactgggtccgccaagctcctgggaaggggctggagtgggtctcacgtatcaatggcgacggaagtcacataagttacgcggactccgtgaagggccgattcgtcatctccagagacaacgccgagaacacactatttctgcaaatgaattctctcagagccgaagatacagccttatatttttgngtgagaggcccgttttagtgtcagttggtatggcaggctggttcgacccctggggccagggaacgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6081 JY8QFUQ01CGZGV unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggcccaggggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6082 JY8QFUQ01CZZJS unproductive Homsap IGHV3-7*01 F 899 91.16 196/215 nt 90.7 195/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.37.11] CAGAEAGL#DYW out-of-frame + in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 189 in the user submitted sequence), (cause frameshift) tctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagcccgaggacacggctgtatatttctgtgcgggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgga +6083 JY8QFUQ01BKOO0 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 962 94.42 203/215 nt 93.49 201/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD2-15*01 F 2 8 7 29 8.7.29 [1.17.38.11] CARVWATEERNCRGATCYYPPMGHFNGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); tctatggtgggtcttttagtggttactactggagttggatacgccagtccccagggaaGggggctggagtggattgGgggaaatcaatcatagtggaagcaccaacttcaacccgtccctcaagagtcgagtcaccatttcagtagacaggtccaagaaccagttgtccctgaggctgacctctgtgaccgccgcggacacggctatgtattactgtgcgagagtttgggcgaccgaagagcgaaattgtcgtggtgcgacctgctactatccccccatgggccacttcaacggtatggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6084 JY8QFUQ01BA26E No results +6085 JY8QFUQ01A4I3A productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ccctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6086 JY8QFUQ01BHQM5 No results +6087 JY8QFUQ01AJOAH productive (see comment) Homsap IGHV3-7*01 F 996 95.0 209/220 nt 94.09 207/220 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARDPYNGGGYGAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); agcctctggattGcacctttagtaataattggatgagttgggtccgccaggctccagggaaggggctggagtAgggtggccaacatcaagcaagatggaagtgagaaagtctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgcaaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagacccctataatggtggtggttatggtgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6088 JY8QFUQ01C55YS productive (see comment) Homsap IGHV3-69-1*01 P (see comment) 365 76.56 98/128 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-8*01 F 2 X 5 17 X.5.17 [X.X.38.11] CVRDVSLYSNDGYDAFDIW in-frame - however the closest V is a pseudogene Low V-REGION identity (76,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagtttttagtaacttttggatgagttggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagagacgtctccctttatagtaatgatggatatgatgcttttgatatttggggccaggggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6089 JY8QFUQ01AZGM1 productive Homsap IGHV3-11*01 F 945 93.09 202/217 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD2-21*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARGKMVSTGMDVW in-frame + Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) ctctggattcacgtttagtgactactacatgacctggattcgtcaggctccagggaagggcctggagtgggttacatatattagtagtagtggtggtaacacacattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaacgcactgtatctgcaaatgaacagcctgagggccgaggacacggccgtgtattactgtgcgcgagggaagatggtgagcaccggtatggacgtctggggccaagggaccacggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6090 JY8QFUQ01DMROR unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGL*QWL##DFDCW out-of-frame + stop codons ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggttatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6091 JY8QFUQ01B4ZPZ productive Homsap IGHV3-23*05 F (see comment) 447 83.08 108/130 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 X 5 16 X.5.16 [X.X.38.11] CAKVMWGVTGPIDPFDYW in-frame + Low V-REGION identity (83,08% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcatcagttatgactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +6092 JY8QFUQ01BFEGM unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ1*01 F (see comment) 143 75.0 39/52 nt Homsap IGHD6-13*01 F 2 8 7 X 8.7.X [2.17.38.11] CARGVGQQLPP*#W out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); gtctctcgtgcctccatcaataCctttttactggagctggatccggcagcccccagggaagggactggagtggattggatatatctatgatagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatctatagacacgtccaagaaccagttctccctgaggctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagaggggtggggcagcaactgcccccttagactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6093 JY8QFUQ01BNQG3 productive Homsap IGHV3-9*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKDIGVHMWTIDYW in-frame + ctctggattcacgtttgatgactatggcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggcattacttggaatagtggttacataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctacagatgaacagtctcagagctgacgacacggccttgtattactgtgcaaaagatattggggtacacatgtggaccattgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6094 JY8QFUQ01BDAEH No results +6095 JY8QFUQ01BDP4Y productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6096 JY8QFUQ01A4IHP No results +6097 JY8QFUQ01BOMRP productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*02 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*04 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*08 F or Homsap IGHV3-30*10 F or Homsap IGHV3-30*11 F or Homsap IGHV3-30*16 F or Homsap IGHV3-30*17 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-3*01 F 402 92.55 87/94 nt 91.49 86/94 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 1 X X 16 X.X.16 [X.X.31.11] CAKDELPWDTIEYYFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); ctctggattcaccatctccagagacaattccaagaacacggtgtatctgcAaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatgagctgccttgggacacaattgaatattattttgactattggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +6098 JY8QFUQ01AG59I No results +6099 JY8QFUQ01DFIB5 productive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); ctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6100 JY8QFUQ01BFS0C unknown (see comment) Homsap IGHV3-52*01 P, or Homsap IGHV3-52*02 P or Homsap IGHV3-52*03 P or Homsap IGHV3-74*01 F or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 121 82.86 29/35 nt 8 X X 8.X.X [1.2.X.X] null - No rearrangement found gtctggatttaccttcagtaagttctggatgcatt +6101 JY8QFUQ01DMF0A productive (see comment) Homsap IGHV4-55*03 P (see comment) 608 75.58 164/217 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARESRNSFGGPTGLDSW in-frame + however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01DMF0A ; 9 AA in Homsap_IGHV4-55*03), and low V-REGION identity (75,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctgttgacgccataagcgacctcggttatttctgggcctgggtccgccagcccgccgcgaagggactggagtggatcggacatgcccttggtgatggatataccgaatacaaccccgccctagagagtcgaatcaccgtgtcagtggacaagtccaagaaccagttttccctgacgttggagtccgtgaccgccgcagacacggccacttatttctgtgcgagggaaagtcggaattcatttggcgggccgacaggccttgattcctggggccagggaattgtggtcatcgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggacgtgtcctcgcctgcctggtccagggcttctccc +6102 JY8QFUQ01C1LQM productive Homsap IGHV3-7*01 F 934 93.43 199/213 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt 8 8 9 8.8.9 [X.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6103 JY8QFUQ01CA2QL No results +6104 JY8QFUQ01AXYNU productive (see comment) Homsap IGHV3-11*01 F 919 93.33 196/210 nt 92.86 195/210 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [X.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 91 in the user submitted sequence), (do not cause frameshift) ggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6105 JY8QFUQ01BKNCA No results +6106 JY8QFUQ01DLZ1V productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 3 8 8 10 8.8.10 [1.17.38.11] CASFRVLESGYW in-frame + ctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttctt +6107 JY8QFUQ01C0X1D No results +6108 JY8QFUQ01ALZG8 No results +6109 JY8QFUQ01BH1Z3 No results +6110 JY8QFUQ01DM1O4 No results +6111 JY8QFUQ01ARMLR productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcatagccgccctgggctgcctagtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6112 JY8QFUQ01AIFNF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame - ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6113 JY8QFUQ01C5RLP No results +6114 JY8QFUQ01A2K1H unproductive Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CLAEVGGRQFDN## out-of-frame + Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccaggggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +6115 JY8QFUQ01C65NA No results +6116 JY8QFUQ01AHFMC No results +6117 JY8QFUQ01CPYST productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcaggc +6118 JY8QFUQ01A1GYW productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 696 80.84 173/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcgggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +6119 JY8QFUQ01DJRFW No results +6120 JY8QFUQ01AY94E productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt 94.12 208/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaaccCcgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6121 JY8QFUQ01CUCST No results +6122 JY8QFUQ01DW81Y productive (see comment) Homsap IGHV4-59*02 F 928 93.36 197/211 nt 92.42 195/211 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD3-16*02 F 3 8 7 16 8.7.16 [0.16.38.11] CASAIMITFGGVIVMTTG in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'AAC' (3 nucleotides at position 23 to 25 in the user submitted sequence), (do not cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) ctggattcaccgtcaataggaaAACgtacatgagctggatccggcagacccccaggaagggactgagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgnccgctgcggacacggccgtgtattactgtgcctcagccattatgattacgtttgggggagttatcgttatgactactggggccaggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6123 JY8QFUQ01C2SCV unproductive (see comment) Homsap IGHV3-48*04 F 936 92.63 201/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKCYQP*IL*PL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtagctatagcatgaattgggtccgccaggctccagggaagggactggagtgggtttcatacattagtggaagtagtaataccatgtactacgcagactctgtgaagggccgattcaccatctcgagagacaacgccaagaacgccctatatctgcaaatgaacagtctgagagttgaggacacggccttgtatttctgtgcaaaatgctaccagccgtgaatactttgaccactgggggccagggaaccctaatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttcccccaa +6124 JY8QFUQ01BMJTK productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6125 JY8QFUQ01B7HNH productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6126 JY8QFUQ01BZWPP unproductive (see comment) Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARVIPGRGK##AFDVW out-of-frame + stop codons ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggcaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +6127 JY8QFUQ01CU8BS productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 7 12 8.7.12 [1.16.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 86 in the user submitted sequence), (cause frameshift) ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaagggctggtgtgggtgtcacgtagtaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +6128 JY8QFUQ01BCV0I productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 649 93.88 138/147 nt 93.2 137/147 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 1 8 X 12 8.X.12 [2.8.31.11] CARRDVGLHAFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 72 nucleotides (from position 55 in the user submitted sequence), (do not cause frameshift) ggttctggatccaattttaactacgactggatcggctgggtgcgccagatgcccggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgcttttgatctgtggggccaggggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct +6129 JY8QFUQ01DQEAT unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 761 83.03 181/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6130 JY8QFUQ01BI9NH unproductive (see comment) Homsap IGHV4-34*03 F (see comment) 574 77.32 150/194 nt 76.8 149/194 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 7 14 8.7.14 [1.17.31.11] CTTRPRGWEPLGLDYW in-frame - stop codons Low V-REGION identity (77,32% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 77 of V-REGION: 20 nucleotides (from position 133 in the user submitted sequence), (cause frameshift) tcgacgatgggtcctgcagaaactgcttctggagttggatccgccagtccccagggaaggggctggagtggattggggaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagatgattcaaaaaacttggtgtttctgcaaatgaacaacctgagaaccgaggacacagccctttattactgtaccacacggccccgggggtgggaaccacttggccttgactactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6131 JY8QFUQ01CSVJ1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctcggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6132 JY8QFUQ01CUU0C productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 859 90.82 188/207 nt 90.34 187/207 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [2.17.38.11] CARHPKSNVEGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 9 nucleotides (from position 16 in the user submitted sequence), (do not cause frameshift) gtctctggtgactctcacttctggagctggatccggcagcccccagggaagggcccggagtggattggttatgtctataacagtgggaccaccaactacaacccctccctcaggagtcgagtcaccatttctatcgacacgtccaagaagcagatctccctgaagttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6133 JY8QFUQ01BGDO5 unproductive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt 99.08 215/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CASRLRSSGGY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaaggggctggagtgggtttcatGacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6134 JY8QFUQ01A2R9O No results +6135 JY8QFUQ01BK8ZG unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 250 58.76 114/194 nt 8 8 X 8.8.X [1.17.30.X] null - No rearrangement found Low V-REGION identity (58,76% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6136 JY8QFUQ01BA7BP productive (see comment) Homsap IGHV3-7*01 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 7 9 8.7.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame + Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 56 of V-REGION: 3 nucleotides (from position 80 in the user submitted sequence), (do not cause frameshift) ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggaggggcgtggagtgggtgccacataagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgccctggtccagggcttcttccccc +6137 JY8QFUQ01CQRBP unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6138 JY8QFUQ01A4PTA unproductive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-22*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDGPPYLYGSHGNSFDQW# out-of-frame + stop codons in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtgggggcccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6139 JY8QFUQ01DL9AO productive Homsap IGHV3-48*01 F 846 88.02 191/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggattcacttttgatgactctgccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcttggaactcag +6140 JY8QFUQ01BYCP5 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6141 JY8QFUQ01DQ18I productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [2.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggGggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6142 JY8QFUQ01DFHQO No results +6143 JY8QFUQ01ALCSF No results +6144 JY8QFUQ01BN0FB No results +6145 JY8QFUQ01CPQ0G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6146 JY8QFUQ01CYXGO unproductive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD2-15*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKGGW*RRP*LLG in-frame + stop codons Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggCccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggctggtaacggcgaccttgactactgggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgccctgcctggtccagggcttcttcccccc +6147 JY8QFUQ01BTSDV unknown (see comment) Homsap IGHV3-72*01 F 238 94.34 50/53 nt 8 X X 8.X.X [1.8.X.X] null - No rearrangement found cctctggcttcatcttcagtgaccactatatggactgggtccgccaggctcca +6148 JY8QFUQ01CGGC1 No results +6149 JY8QFUQ01DVZZK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcccagggcttcttcccccga +6150 JY8QFUQ01BPF6G No results +6151 JY8QFUQ01AZM4V No results +6152 JY8QFUQ01BJJ7G productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6153 JY8QFUQ01BSD92 productive (see comment) Homsap IGHV4-61*02 F 986 94.95 207/218 nt 93.58 204/218 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-10*01 F 2 9 7 13 9.7.13 [1.17.38.11] CARGSGTYYNPMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'ACTG' (4 nucleotides at position 34 to 37 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 3 nucleotides (from position 30 in the user submitted sequence), (do not cause frameshift) tttctggtgcctccatcagcagtggtagttactACTGgggactggatccggcagcccgccgggaagggactggagtggattgggcgtatccataccagtgggggAcaccaactacaccccctccctcaagagtcgactcaccatatcagtagacgcgtccaagaaccaggtctccctgaggctgagctctgtgaccgccgcagacacggccgtgtattactgtgcgagaggttcggggacttattacaaccctatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6154 JY8QFUQ01ATVRQ unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.1 219/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactGactggggctggatccgccagcccccagggaaggggctggagtggattgggagtaCtctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgaccggtgtcgtggaactcag +6155 JY8QFUQ01A38FQ unknown (see comment) Homsap IGHV4-61*02 F (see comment) 702 80.65 175/217 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgccctttgtacacaccgcccgtcgctactaccgattggatggtttagtgaggccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6156 JY8QFUQ01CI1J0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggaaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6157 JY8QFUQ01AHUB9 unproductive Homsap IGHV3-7*01 F 1047 99.07 212/214 nt 98.13 210/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.37.11] CARDKYYDFWSDHYPGG#YGMDVW out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 99 of V-REGION: 2 nucleotides (from position 199 in the user submitted sequence), (cause frameshift) tctggattcaccGtttagtagctattggatgagctgggtccgccaggctccagggaaggggctggagtggtgggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacggctgtgtattactgtgcgagagacaagtattacgatttttggagtgatcattacccagggggggtacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6158 JY8QFUQ01BNJ81 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame + ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +6159 JY8QFUQ01BS6C5 unproductive (see comment) Homsap IGHV4-4*07 F, or Homsap IGHV4-59*10 F or Homsap IGHV4-61*02 F 596 86.71 137/158 nt 85.44 135/158 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt X 6 X X.6.X [X.9.37.X] null - stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 43 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 98 of V-REGION: 1 nucleotides (from position 141 in the user submitted sequence), (cause frameshift) gggaagggcctggagtggatcggacgtatttatgacagtggcagtgactacaatccttctctcaagagtcgagtcaccatgtcagtagacacgtccaagagccagttctccctgaggctgagttctgtggccgccgcagaacggccgtttacttctgtgcgatagaacgtagtagatcgattggcggagacggacaaatttgactttctgggggccagggaacccctggtcacccgtctccctagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6160 JY8QFUQ01CHV4Z productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [2.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6161 JY8QFUQ01BNA9I No results +6162 JY8QFUQ01ADD1O productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +6163 JY8QFUQ01BDTYM productive (see comment) Homsap IGHV3-48*01 F 1085 100.0 218/218 nt 99.08 216/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6164 JY8QFUQ01DBCR2 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 348 86.02 80/93 nt 8 5 X 8.5.X [1.17.X.X] null + No rearrangement found tctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc +6165 JY8QFUQ01DMUXO productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 924 91.36 201/220 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggtggctccgtcagcagtaggggttactactggaactggatccgccagttcccagggaagggcctggagtggattgggaacatcttttacagtgggggcacctacgacaacccgtccctcaggagtcgaatttctatatcattagacacgtctaagaaccaattctccctgaagttgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc +6166 JY8QFUQ01A9I9K No results +6167 JY8QFUQ01BDH99 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaAaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6168 JY8QFUQ01DAW4B No results +6169 JY8QFUQ01B61ES No results +6170 JY8QFUQ01BOAMW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6171 JY8QFUQ01BKT0I No results +6172 JY8QFUQ01DGTXX unproductive (see comment) Homsap IGHV4-39*03 F 928 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD3-22*01 F 1 9 7 X 9.7.X [1.17.38.11] CARSITLTVVVMND##FDVW out-of-frame - stop codons in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) ctccggtggctccatcaacagtagaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgccttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6173 JY8QFUQ01BS4F8 unproductive (see comment) Homsap IGHV3-7*01 F 936 92.63 201/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt 8 8 X 8.8.X [1.17.38.11] CATSP*RLLTDDGGLLG (see Functionality comment) out-of-frame + stop codons, IMGT/JunctionAnalysis gives no results for this JUNCTION in FR2-IMGT at codon 51 of V-REGION: 'GA' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); ctctggatttagctttagaaccttttggatgagctgggtccgccaggctccagggaggggcgtggaGAgtgggtggccaaTcataaagtcagatggGaagtgaCaaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctccccctagcgacttttgacagacgatggggggttactgggggcccaaggggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtctttccccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +6174 JY8QFUQ01AHXIB productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6175 JY8QFUQ01CD6S8 No results +6176 JY8QFUQ01B5QXF productive Homsap IGHV3-48*01 F 1070 99.53 214/215 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [0.17.38.11] CASIFGVVPLGNYYYGMDVW in-frame - ctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6177 JY8QFUQ01BTMEZ No results +6178 JY8QFUQ01AM3RG No results +6179 JY8QFUQ01BDUFZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDATAISSGYYHRLDYW in-frame + ctctggcttcacctttgaaaattatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtcgcagcaatcagtcttagtggtggaagtacatacttcgcggactccgtcaagggccggttctccatcgcccgggacaactccaaggacaccctgtatcttcacatggacagcctgagagccggggatacggccacatattattgtgcgaaagacgcaactgcgattagtagcggttattatcaccgacttgactactggggccagggtaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +6180 JY8QFUQ01CBST2 productive Homsap IGHV3-11*01 F 929 91.4 202/221 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [2.17.38.11] CARVKYSSSWSSILDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cagcctctggattcaacttcggtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtttcattcattagtagtcctggtatcaggagtttctacgcagactctgtgaagggccgattcactatttccagggacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgaggacacggccatatattactgtgcgagagtgaaatatagcagcagctggtcctcaatccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6181 JY8QFUQ01AG9UH unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-16*02 F 2 8 8 X 8.8.X [0.17.38.11] CARGDLP#YIDYW out-of-frame - tggatacatcttcaccagctactttatgcactgggtgcgacaggcccctggacaagggcttgagtggatgggaatagtcaaccctagtggagctggcacaacttacgcacagaagttccagggcagagtcaccatgaccagcgacacgtccacgaccacagtctacatggagctgagcagcctgagatccgacgacacggccatatattactgtgcgagaggcgatctccccactacattgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6182 JY8QFUQ01CIA8P productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6183 JY8QFUQ01BL0M4 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 905 90.83 198/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD6-19*01 F 1 9 7 20 9.7.20 [1.17.38.11] CVRDGRRTYNSGWYSLAAFDIW in-frame + tctctggtgtctccatcagcagtggtaactggtggagctgggtccgccagcccccagggaaggggctggaatggattggagaaatctcttatagtgggaccaccaagtacaaccggtccctcaagagtcgagtcaccatatcactagacacgtccaaaaaccatttctccctgcagctgacttctgtgaccgccgcggacacggctgtctattattgtgtgagagatggtcgccggacctataacagtggctggtattcgttagctgcttttgatatctggggccaggggacagtggtcaccgtctcttccgcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +6184 JY8QFUQ01CX0E8 No results +6185 JY8QFUQ01CFBH9 productive Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*02 F or Homsap IGHV3-33*03 F (see comment) 376 78.86 97/123 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 X 3 17 X.3.17 [X.X.38.11] CAKDTITMGGDVAPLFDYW in-frame - Low V-REGION identity (78,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release acctctggattcacctttaactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6186 JY8QFUQ01A5NH7 No results +6187 JY8QFUQ01DW085 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6188 JY8QFUQ01AVQDO No results +6189 JY8QFUQ01BGW7G No results +6190 JY8QFUQ01ABYMU No results +6191 JY8QFUQ01AGE1J No results +6192 JY8QFUQ01BJEZU No results +6193 JY8QFUQ01DJ2RD unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARVGYGYRGIYFFDY## out-of-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccaagggaaccctggtcaccgtctcctcagcctccaccaagggcccaatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6194 JY8QFUQ01A7RY0 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 878 89.45 195/218 nt Homsap IGHJ4*03 F 123 72.92 35/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CSKTHLGE#DYW out-of-frame - cctctggattctccgtcagtaattactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaagacacatttgggcgagaagactactgggccagggaggccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +6195 JY8QFUQ01A28YA No results +6196 JY8QFUQ01CR1W7 No results +6197 JY8QFUQ01BGKCU No results +6198 JY8QFUQ01A97AT No results +6199 JY8QFUQ01DI5MR productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD5-18*01 F 3 10 7 14 10.7.14 [2.16.37.11] CARSQSRYSWGDFLHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 70 of V-REGION: 1 nucleotides (from position 121 in the user submitted sequence), (cause frameshift) gtctctggtgactccatcagcagtactagttactactggggctggatccgccagccccagggagggggctggagtggattggaagcatctattatagtgggagcacctcctacaacccgtcctcgagagtcgaatcaccatgtccgtagacatgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtttatttctgtgcgcggtcccagagtagatacagttggggtgacttcttacactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6200 JY8QFUQ01DBT6J unproductive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 X 8.7.X [1.17.38.11] CARGHFR**WLFQP#LDHW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 91 to 96 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagttTtctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttcgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctcgacagcaccccccaagcatggaacgtgtcgtcgcatgcctggtccagggcttcttcccccag +6201 JY8QFUQ01BOIP3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + tctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6202 JY8QFUQ01DQZFP No results +6203 JY8QFUQ01DBIOF productive Homsap IGHV3-9*01 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame + ctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6204 JY8QFUQ01CI5CF No results +6205 JY8QFUQ01DH145 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 940 93.06 201/216 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [2.17.38.11] CARAPRTATLLDPW in-frame - gtctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6206 JY8QFUQ01CBO42 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6207 JY8QFUQ01DI164 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 494 96.23 102/106 nt 8 8 X 8.8.X [1.17.1.X] null + No rearrangement found tctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatact +6208 JY8QFUQ01CLEAH productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARGEFYYETSGRRGFDYW in-frame - ctctggattcaccttcactacctcctggatgcactgggtccgccaagctccagggaaggggctaatgtgggtcgcacgtattaataaggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaccacactgtacttggaaatggacagtctgagagtcgaggacacggctatgtattattgtgcaagaggggaattttactatgaaactagtggtcgaaggggttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6209 JY8QFUQ01ABF8G productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 875 88.69 196/221 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 2 10 7 16 10.7.16 [1.17.38.11] CTNDRSMAVRATHAFHIW in-frame + tctctggtgactccattggtagcagtgcctactactggggctgggtccgccagccccccgggaaggggctggagtggattggaagtatctattatggtggcaacacctactacaacccgtccctcaggagtcgagtcagcatttccgcagacacgtccaagaaccagttctccctgcatctctactccgtgaccgccgcagacacggctctgtattactgtacgaatgaccgttcgatggccgttcgtgcaactcatgcttttcatatctggggcctagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6210 JY8QFUQ01AD6NQ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 407 79.23 103/130 nt 77.69 101/130 nt 7 6 X 7.6.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (79,23% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) tctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6211 JY8QFUQ01CUO32 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6212 JY8QFUQ01C2LVB No results +6213 JY8QFUQ01CNBY9 unproductive (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F (see comment) 408 80.65 100/124 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-21*02 F 2 X 3 X X.3.X [X.X.38.11] CASFAGPVVVTL*WLLVRLT#YCDYR out-of-frame + stop codons Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctgcattcaccgtcagtaggctccgtgacgggccgagtcatcatctccagagagaatgcccagaactccgtgtatcttccactgaacagcctgagagccgggaacacggctgtgtatcactgcgcaagttttgctggccctgtggtggtgactctatagtggctgttggtccgtctgaccactactgtgactaccggggcctgggaaccccggtcccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6214 JY8QFUQ01CC175 No results +6215 JY8QFUQ01AVOJA productive Homsap IGHV3-9*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + ctctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6216 JY8QFUQ01BH7IW productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.37.11] CAREVIPTATYGMDLW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 98 of V-REGION: 1 nucleotides (from position 197 in the user submitted sequence), (cause frameshift) gtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagcagcgagacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6217 JY8QFUQ01CWJN1 No results +6218 JY8QFUQ01AQ36T productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + gctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6219 JY8QFUQ01DHC55 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6220 JY8QFUQ01AFRTD No results +6221 JY8QFUQ01B5QM6 productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +6222 JY8QFUQ01AROL9 unknown (see comment) Homsap IGHV3-23*05 F 102 55.24 58/105 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons cctctggattcgtctttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6223 JY8QFUQ01C00ZK productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 7 21 8.7.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6224 JY8QFUQ01BU9ER No results +6225 JY8QFUQ01CWZ8I No results +6226 JY8QFUQ01C7M0Q productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggcGtggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccCctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6227 JY8QFUQ01DGOJK No results +6228 JY8QFUQ01DLDT4 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [2.17.38.11] CARDRLTISALDYW in-frame - stop codons in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 16 to 17 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'T' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'A' (1 nucleotides at position 218 to 218 in the user submitted sequence), (cause frameshift); gcctctggattcaccCTtttaacaactaCggccatgtcctgggtccgccaggctccagggaaAggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaTggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtataAtttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6229 JY8QFUQ01DECPM productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 817 87.32 186/213 nt 86.85 185/213 nt Homsap IGHJ1*01 F (see comment) 188 84.62 44/52 nt Homsap IGHD1-26*01 F 1 8 7 13 8.7.13 [1.17.37.11] CVGVGVGSSVSFQYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 87 of V-REGION: 1 nucleotides (from position 163 in the user submitted sequence), (cause frameshift) ctctggattcactgtcaataacaactacatgggttgggtccgccaggctccagggaaggggctggagtgggtctcgactatttattacggtggcaccacatattacgcagactccgcgaagggccgattcaccatctccagagacacctccaggaacacacttttcttcagatgaacagcctgagaagcgacgacacggctctatattattgtgtgggagtcggagtgggatcttcagtctccttccaatactggggccagggcacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6230 JY8QFUQ01CW5NA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctccgtcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6231 JY8QFUQ01AY4JM productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6232 JY8QFUQ01DT7AW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 904 91.2 197/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - tctcgattcacctttagcagctatgtcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6233 JY8QFUQ01A5QD0 No results +6234 JY8QFUQ01DMASI unproductive (see comment) Homsap IGHV3-48*03 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); ctctggattcacctttactagttaCagttttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaacctgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6235 JY8QFUQ01BAV7R productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6236 JY8QFUQ01B95YA No results +6237 JY8QFUQ01B8PU0 productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1002 96.73 207/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFYYW in-frame + tggatacaccttcaccagctactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagacttttactactggggccagggaaccctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6238 JY8QFUQ01CDPWD productive Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6239 JY8QFUQ01CNBDG No results +6240 JY8QFUQ01CSQN6 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1033 98.59 210/213 nt 98.12 209/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.37.11] CASANYDYVWGSYRYDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 99 of V-REGION: 2 nucleotides (from position 198 in the user submitted sequence), (cause frameshift) tctctggtgcctccatcagtccttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6241 JY8QFUQ01B4RF9 No results +6242 JY8QFUQ01CM8P9 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDAFEMW in-frame + ctctggattcatctttgatgattttggcatgaattgggtccgccaagctccagggaaggggctggagtgggtcgctggtatcagttggaatggtggcaaagcaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcaatgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6243 JY8QFUQ01BLJ6R unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 595 82.66 143/173 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found Low V-REGION identity (82,66% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaggggctggagtgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgc +6244 JY8QFUQ01A3F5T productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcacctttgatgattttggcatgagatgggtccgccaagtcccagggaaggggctacagtgggtctctgggattaattggaatggtgctaaaacaggttatgcagcctctgtgcagggccgattcaccatctccagagacaacgacaacaacgtcctgtatctgcaaatgaacagtttgagacccgaggacacggccttgtatcgctgtgcgagagaggtttcggacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +6245 JY8QFUQ01CDDRR productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1091 99.55 220/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgagagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6246 JY8QFUQ01CZ7EK No results +6247 JY8QFUQ01BLBZG No results +6248 JY8QFUQ01BS864 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 880 90.61 193/213 nt 90.14 192/213 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.37.11] CVSDLAGQKGFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 165 in the user submitted sequence), (cause frameshift) aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6249 JY8QFUQ01AUUYM unknown (see comment) Homsap IGHV3-72*02 F 129 53.46 85/159 nt 8 8 X 8.8.X [1.17.30.X] null + No rearrangement found stop codons tctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +6250 JY8QFUQ01BX3EL No results +6251 JY8QFUQ01CXFTB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6252 JY8QFUQ01ALNPO No results +6253 JY8QFUQ01CTNRY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 897 90.0 198/220 nt 89.55 197/220 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); agcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttaCctggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccctgaaccggtgacggtgtcgtggaactcag +6254 JY8QFUQ01AHZXQ unproductive Homsap IGHV3-9*01 F 882 89.86 195/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDVTSESHFFALDV## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctcgggattcaagtttgatgaatatgccatgcactgggtccggcgagttccagggaggggcctggagtgggtctcagttataagttgggatggtgatgacatcgcctatgcggactctgtgaagggccgattcagcatctccagagacaacgccaagaactccctgtacctggaaatgagcagtctgagagttgaggacacggccttctattactgtgcaaaggatgtcacatctgaaagtcatttcttcgctttggacgtctgggggccaagggaccgcggtcaacgtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6255 JY8QFUQ01COSNV No results +6256 JY8QFUQ01CFWG2 No results +6257 JY8QFUQ01CBKG2 productive (see comment) Homsap IGHV3-23*05 F 822 87.38 187/214 nt 86.92 186/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaagggtcttcccgctgagcctcgacagcaccccccaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccccca +6258 JY8QFUQ01BMXML No results +6259 JY8QFUQ01BO55X unproductive (see comment) Homsap IGHV3-72*01 F 523 86.96 120/138 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-6*01 F 2 X 8 X X.8.X [X.X.38.11] CPREL*EVDFAR#W out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcccagttagaccacagactacgccgcgcctgtgaaaggcagattcaccatttcaagagatgattcaaagtaatcactgtatctacaaatgaacagcctgaaaaccgaggacacggtcgtgtattagtgtcctagagaattataggaggtcgattttgctcgttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6260 JY8QFUQ01BNU7I productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 709 81.69 174/213 nt 81.22 173/213 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.37.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 130 in the user submitted sequence), (cause frameshift) ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +6261 JY8QFUQ01CZ5K0 unknown (see comment) Homsap IGHV4-61*02 F (see comment) 509 77.33 133/172 nt 76.74 132/172 nt 10 7 X 10.7.X [1.17.22.X] null - No rearrangement found Low V-REGION identity (77,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'AG' (2 nucleotides at position 106 to 107 in the user submitted sequence), (cause frameshift); gtctggtggctccatcagcagtgatgattactactggagctggatacggcagtccgccgggaagggactggagtggattgggcgaatttataaaagtggcgacacAGtgatcacaaccctccctgcggggggcgagtcgccatgtcactggacacgtccagggcttcttcccca +6262 JY8QFUQ01BWJF3 No results +6263 JY8QFUQ01CLDYZ No results +6264 JY8QFUQ01AWTQR productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 890 90.7 195/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD5-18*01 F 3 10 7 17 10.7.17 [1.17.38.11] CAGEQMIDAVSHNYAMDVW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01AWTQR ; 8 AA in Homsap_IGHV4-59*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggctccatcagcatcaatacttacttctggagttggatccggcagcccccagggaagggactggagtggattgggtatatctctcacagtgggagtgccaactacaacccctccctcgagagtcgagtcaccatcttaagagacacgtccaagaaccagttctctctgaggctgagggctgtaaccgcggcggacacggccgtgtatttctgtgcgggggaacagatgattgacgcagtctcccacaactatgccatggacgtctggggccaagggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +6265 JY8QFUQ01AGMA8 unknown (see comment) Homsap IGHV4-61*02 F 884 89.14 197/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc +6266 JY8QFUQ01AA0SS No results +6267 JY8QFUQ01C6HW4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ3*02 F 250 100.0 50/50 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKRLEGVADDAFDIW in-frame - cctctggattcacctttagcagctatgccatgggctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtgggagtggtcggagcacatactacgcagactccgtgaagggccggtacaccatctccagagacaattccaagaatacgatgtctgtgcaaatgagcagcctgagagtcgaggacacggccatatattattgtgtgaaaaggttggaaggagtggctgatgatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6268 JY8QFUQ01BRQL0 unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 945 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found gtctggcttcacgttcagtagttatggcatgcaatgggtccgccaggctccaggcaaggggctggagtgggtggcagttatttggtatgatggaagtaataaatattatgcagactccgtgaagggccgattcgacatctccagagacaattccaagaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatgtaccattgtgcgagaggcggcggtgcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggccttcttcccccga +6269 JY8QFUQ01BK2CH productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +6270 JY8QFUQ01B9AGF unproductive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDDKWAFDY# out-of-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgacagccgaggacacggctgtttattactgtgcgagagatgataagtgggcatttgactactgggccagggaaccctggtcgtcgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccg +6271 JY8QFUQ01CO0WU No results +6272 JY8QFUQ01DNMM3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagg +6273 JY8QFUQ01DIYR4 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 886 90.28 195/216 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKIV*YTR*G#AFDMW out-of-frame - stop codons tctggattcaccttcagaaccaatgccatgaactgggtccgccaggctccagggaaggggctggagtggatctcagttattaatggtcccggtgatatcacatactacgcagactccgtgaagggccggttcaccatgtcccgagacaattccaaggacacgttgtatttgcaaatgatcagcctgagaggcgaggacacggccatatattactgtgcaaagatcgtatgatacacacgatgaggggagcttttgatatgtggggccgagggacaatggtcaccgtctcttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6274 JY8QFUQ01AM0AD productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [2.17.37.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'GA' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 113 in the user submitted sequence), (cause frameshift) agtctctggattcaccgtcaatagGAaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6275 JY8QFUQ01B6Y0Z unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 135 100.0 27/27 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found tctccggggacagtgtctctagcaaca +6276 JY8QFUQ01AHK2I productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6277 JY8QFUQ01ATP5E No results +6278 JY8QFUQ01BT2TZ No results +6279 JY8QFUQ01CQ3YF unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 216 97.78 44/45 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found ctctggattcaccttcagtagctactggatgcactgggtccccca +6280 JY8QFUQ01CXLJP No results +6281 JY8QFUQ01A3J3K No results +6282 JY8QFUQ01DQSTN No results +6283 JY8QFUQ01AQJZF productive Homsap IGHV3-7*01 F 852 87.73 193/220 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - gcctctgggtttcacatttagtacgtactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcgagatggaactgagagtcattatgtggactctgtgaagggccgattcatcatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6284 JY8QFUQ01B0SVG No results +6285 JY8QFUQ01BOH7B productive Homsap IGHV1-8*01 F 844 88.26 188/213 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [X.17.38.11] CARVGETHYHYGVDVW in-frame + ggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagatctgacgacacggccgtgtattattgcgcgagagtcggtgagacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6286 JY8QFUQ01C4IX9 productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6287 JY8QFUQ01BBNT0 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 867 87.44 195/223 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD1-14*01 ORF 1 8 10 X 8.10.X [1.17.38.11] CTADVPSPLAQNDF# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcactttcaatggcgcctggatgaactgggtccgccaggctccagggaagggtctggagtgggttgcccgtataaaaacttttggtgaaggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcaaaaaaagggctgtatctgcagatggacagcctgagaatcgaggacacagccaagtattactgcaccgcagatgtcccgtcaccattagcgcaaaatgacttctgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +6288 JY8QFUQ01C84Q1 No results +6289 JY8QFUQ01AFZCG productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 932 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6290 JY8QFUQ01AHS1H unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6291 JY8QFUQ01DK4RM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccgag +6292 JY8QFUQ01C470B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 842 87.61 191/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CVRESFSRTIDSW in-frame - Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tgtctggattcatctttagcagatatgccatgagttgggtccgccagcctccagggaaggggctggagtgggtctcagccatagttggtagtggtggtggtgcatactacgcagactccgtgaagggccggttcaccgtctccagagacaatgatgaaaacaccctgtctctgcaaatgagcagcctgagagtcgaagacacggccatgtattattgtgtgagagaatcatttagcaggacgattgactcttggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6293 JY8QFUQ01BKNBD No results +6294 JY8QFUQ01CQML7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 169 82.0 41/50 nt Homsap IGHD4-17*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDRLNGDYTFGAFDLW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctaaatttgacttcagtgactatggcatgaactgggtccgccaggttccagggaaggggctggagtgggtctcctacataagtcgtctgagtcgccaaatatatgtcgctgacccagtgaagggccgattcaacatctccagagacaacgccaagaattcactgtatctgcaaatgaacaacttgcgggtcgaagacacggctgtgtatttttgtgccaaagatcgcctgaacggtgactacacattcggcgcatttgatctgtggggcccagggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +6295 JY8QFUQ01CWB3S No results +6296 JY8QFUQ01BEJUJ productive Homsap IGHV3-7*01 F 955 93.15 204/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSAYFSTGYW in-frame - gcctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6297 JY8QFUQ01B8977 No results +6298 JY8QFUQ01DU32V unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F (see comment) 262 57.53 126/219 nt 57.08 125/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (57,53% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'CT' (2 nucleotides at position 37 to 38 in the user submitted sequence), (cause frameshift); gggtctggatacatctttaatatccactggatcgccCTggggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6299 JY8QFUQ01B8UEP unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6300 JY8QFUQ01CKVS0 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 228 57.44 112/195 nt 8 8 X 8.8.X [1.17.30.X] null + No rearrangement found Low V-REGION identity (57,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcaatagttactggatgcactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6301 JY8QFUQ01A6W08 productive (see comment) Homsap IGHV3-7*01 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 176 86.96 40/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.37.11] CSRLLEEW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +6302 JY8QFUQ01B31FY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6303 JY8QFUQ01DH69T productive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [1.17.38.11] CARVIPGRGNYAFDVW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6304 JY8QFUQ01BGFAG productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1040 97.71 213/218 nt 97.25 212/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [2.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6305 JY8QFUQ01CCY1K productive (see comment) Homsap IGHV3-72*01 F 1053 96.46 218/226 nt 96.02 217/226 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-11*01 ORF 2 8 10 13 8.10.13 [2.17.38.11] CVRGLHSNYYGMDVR in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtgaccactacatggactgggtccgccaggctccagggaAaggggctggagtgggttggccgtagtagagacaaagttaacagttacagcacagaatacgccgcgtctgcgaagggcagattcaccatctcaagagatgaatcaaagaactcactgtatctgcaaatgaacagcctgaaaagcgaggacacggccgtgtattactgtgttagaggcctacacagtaattactacggtatggacgtcaggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6306 JY8QFUQ01B8Y2R productive Homsap IGHV4-39*02 F 947 92.31 204/221 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD5-18*01 F 1 10 7 14 10.7.14 [1.17.38.11] CARGMDTTRVARLDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tctctggtgactccatttccagtactagttattactggggctgggtccgccagcccccagggaaggggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggcagtttactattgtgcgaggggaatggatacaactagggtcgcccgtttggatgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +6307 JY8QFUQ01ARZ0L unproductive Homsap IGHV3-48*03 F 883 89.5 196/219 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-8*02 F 3 8 8 X 8.8.X [2.17.38.11] CARESWWSGFM#WYDPW out-of-frame - gcctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggctttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6308 JY8QFUQ01C979I productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1043 98.6 212/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - tctctggtggctccatcagtagttactactggagctggatccggcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6309 JY8QFUQ01DXBXM No results +6310 JY8QFUQ01CRX09 No results +6311 JY8QFUQ01DJLI0 productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAYFSTGYW in-frame - ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6312 JY8QFUQ01DO3JY productive (see comment) Homsap IGHV4-39*02 F 947 91.86 203/221 nt 90.95 201/221 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [2.16.38.11] CARRYSWNYERFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gtctctggtgactccatcagtactaataattactactCgggcctggatccgccagccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcgggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6313 JY8QFUQ01DLZKB productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6314 JY8QFUQ01A7CMG productive Homsap IGHV1-3*01 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame + tggatacatattcaccgacttttatatacactgggtgcgacaggcccctggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccg +6315 JY8QFUQ01AH1M0 No results +6316 JY8QFUQ01DEZMP unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +6317 JY8QFUQ01A4W5D productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 921 92.52 198/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame + ctctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6318 JY8QFUQ01BXFLS unproductive Homsap IGHV4-61*02 F 879 89.09 196/220 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD3-22*01 F 1 10 7 X 10.7.X [1.17.38.11] CSRSLPRGYYYYGVGI# out-of-frame + ctctggtggctccatcggtagtggaaattattactggagctggattcgacagaccgccggaaagggactggagtggattgggcggatatatagtactgggagcaccgactacaacccctccctcaacagtcgagtcaccttgtccatggacacgtccaagaaccagttctccctgaaactgggctctgtgaccgccgcagacacggccgtctattactgttccaggtctcttccacgaggctactactactatggtgtgggcatctgggcccagggaccacggtcgtcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccc +6319 JY8QFUQ01BW0IZ productive (see comment) Homsap IGHV3-33*05 F (see comment) 742 82.87 179/216 nt 81.94 177/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.16.38.11] CVKGRGYNDYGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaagggctggagtgggtggcgaccatttcatatgatAttaatgaaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6320 JY8QFUQ01DJV69 productive Homsap IGHV3-48*04 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CASFSGWEHEYW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtttcctcgattattagtagtggtagcaatatatacgacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcgagcttcagtgggtgggagcatgagtactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaa +6321 JY8QFUQ01BQY7O No results +6322 JY8QFUQ01B22ET No results +6323 JY8QFUQ01BZ8IQ unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1030 97.69 211/216 nt Homsap IGHJ4*03 F (see comment) 132 75.0 36/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARPYCGGDCHNRGAFDI# out-of-frame + Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctgggccaagggacaatggtcaccgtctcttcagcatccccgaccagcccctaaggtcttcccgctgagctcgacagcaccccccgaagatgggaacgtggtcgtcncatgcctggtccagggcttcttccc +6324 JY8QFUQ01BICWN No results +6325 JY8QFUQ01CIJ1X No results +6326 JY8QFUQ01A7A2W productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 817 87.32 186/213 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [X.17.38.11] CAKDRLDSSGHYYHGVYYYGMDVW in-frame - ggatttagttttgaaaactatggcatgcattgggtccgccaggctccaggcaagggcctggaatgggtggcggtgatatcatatgacgcaagtaacaaatattatgcagacgccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatcttcaaataatcggcctgagagctgaggacacggctaaatactactgtgcgaaagatcgccttgacagcagtggtcattactaccacggggtctactactacggaatggacgtctggggcccagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6327 JY8QFUQ01A0LEW productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CASAPSDSSGYYFSYW in-frame + tggatacaccttcaccagttactatatgcactgggtccgacaggcccctggacaagggcttgagtggatgggaatgatcaaccctagtggcggaagcacaatctacgcacagaacttccagggcagagttgccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgctagcgccccctctgatagtagtggatactacttttcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6328 JY8QFUQ01BJDQ8 No results +6329 JY8QFUQ01B0Q68 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 895 88.44 199/225 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-22*01 F 2 8 10 14 8.10.14 [2.17.38.11] CTSRYYDPSGYWSDPW in-frame + tctctgggggtcaccttcagtgacgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcagagttgatggtgggacagtggactacgctgcacccgtgaaaggcagattcaccatctcaagagatgactccaaaaacacactatatctacaaatgaacagcctgaaaatcgaggacacagccatgtatttctgcaccagtcgatactatgatcctagcggttactggtccgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +6330 JY8QFUQ01CP0DL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6331 JY8QFUQ01BDF9A No results +6332 JY8QFUQ01C0A0U productive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); ctctacattcacgGtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6333 JY8QFUQ01AONND No results +6334 JY8QFUQ01AHIGQ No results +6335 JY8QFUQ01A3YON productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6336 JY8QFUQ01BSCQK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 910 90.87 199/219 nt 90.41 198/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); gcctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcaCcaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6337 JY8QFUQ01AIX9W unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-25*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGGW*R##LDYW out-of-frame + stop codons ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggatggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +6338 JY8QFUQ01BH98U unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 858 89.25 191/214 nt Homsap IGHJ3*02 F (see comment) 187 86.0 43/50 nt Homsap IGHD6-13*01 F 2 8 7 X 8.7.X [1.17.38.11] CARPTYSSGRD#AFDTW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) ctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggactgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6339 JY8QFUQ01A4PD9 No results +6340 JY8QFUQ01CSW02 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.43 191/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame + tctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6341 JY8QFUQ01B5B1Z productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6342 JY8QFUQ01CRVEX No results +6343 JY8QFUQ01CZJC9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6344 JY8QFUQ01CJ7SM No results +6345 JY8QFUQ01C8OZP No results +6346 JY8QFUQ01ARWC9 unproductive Homsap IGHV3-7*03 F 1031 97.25 212/218 nt Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAREVSD#FEMW out-of-frame - cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgctttgaaatgtggggtcaagggacaacggtcaatgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6347 JY8QFUQ01CCPNN unproductive Homsap IGHV3-53*04 F 791 85.58 184/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CARQTAPLWEL#DLW out-of-frame + ctcgggggttcaccgtccaaaacagcttcatgagttgggtccgccaggctccagggaagggcctagagtgggtctcagttgtttatagtggtggatccacatactacgcagactccgtgaagggccgtttcaccatcgccagacacagtcgcaacaacattctgtatcttcaaatgaacagcctgagacctgaggacacggctgtttacttctgtgcgagacagactgcccccctttgggaactttggacttatggggccagggaaccctggtcaccgtctcttcagcatccccggaccagcccccaaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttc +6348 JY8QFUQ01ATL2Q productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgAaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtggggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +6349 JY8QFUQ01C3GYW No results +6350 JY8QFUQ01BC7K6 No results +6351 JY8QFUQ01BGPBX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CTKDYPDGRLLNHVLPFLT#W out-of-frame - cctctggattcacgtttgacgactatgccatgagttgggtccgccaggctccagggaaggggccggagtgggtctcaggtattattcctaatagtcgtgacagacactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagagcacagtgtatctgcaaatgaacaacctcagaggcgaggacacggccgtatattactgtacgaaagactatccggacggccgcctgctaaatcacgtccttccctttttgacacttggggcgagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6352 JY8QFUQ01BY17I No results +6353 JY8QFUQ01BA2VC productive (see comment) Homsap IGHV4-39*02 F 951 92.27 203/220 nt 91.82 202/220 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [1.16.38.11] CARRYSWNYERFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtactaataattactactgggcctggatccgccagcccccagggaggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6354 JY8QFUQ01ACT7P productive Homsap IGHV3-11*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 14 8.8.14 [1.17.38.11] CTRDDRSVRGVTSDYW in-frame + ctctggattcaccttcagtgaccacttcatgagttggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggcagtggtagtataatatattacgcagactctgtgaggggccgattcaccatctccagggacaacgccaagaattccctctatctgcaaatggacagcctgagagacgaggacacggccgtgtatttttgtacgagagatgatcgctcggttcggggagtcacctcagactactggggccagggaaccctggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6355 JY8QFUQ01A6EZC productive (see comment) Homsap IGHV1-69*06 F, or Homsap IGHV1-69*14 F 848 89.15 189/212 nt 88.21 187/212 nt Homsap IGHJ6*02 F (see comment) 229 85.48 53/62 nt Homsap IGHD4-17*01 F 2 8 8 18 8.8.18 [0.16.38.11] CARSDFGAYPTYYYYFMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 54 of V-REGION: 2 nucleotides (from position 72 in the user submitted sequence), (cause frameshift) tggaggcaccttcagtagttacgcaatcagctgggtgcgacaggAcccctgggcaagggcttgagtggatgggggatcatccctaagtttggaagaacaaactacgcacagagtttccagggcagagtcacgattaccgcggacaaatctacgaggacagtctacttggagttgagtagcctgcgatctgaagactcgggcgtgtatttctgtgcgaggagtgacttcggggcctaccctacatactactactactttatggacgtctggggccgtgggaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6356 JY8QFUQ01ALRP1 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 858 89.25 191/214 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CASGGYSGSGEYFLR## out-of-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctgggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +6357 JY8QFUQ01A3Z6E productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARFGPLTRPDYWG in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggcccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6358 JY8QFUQ01CJVSG unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*08 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 7 X 8.7.X [1.17.38.11] CGRGGKQWL#YFDYW out-of-frame + stop codons ctctggcttcacttttaggggctatgctatgagctggctccggcagcccccagggaagggactggagtggattgggtatatttattaccctaggagtaccaactacaacccctccatccagagtcgagtcaccatatcagtagacacgtccgagaaccagttctccctgaagctgtattctgtgaccgctgcggacacggccgtgtatcactgtgggagagggggcaagcagtggctggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6359 JY8QFUQ01A8HIE productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6360 JY8QFUQ01DNPNL No results +6361 JY8QFUQ01DEC3Y unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 827 87.44 188/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 8 X 8.8.X [0.17.38.11] CARDSHKPPTVT#YFDYW out-of-frame + ctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggccccagggaaggggccggagtgggtctcagttatcagtggttggggtaatactatatattatgcagactccgtgagaggccggttcaccatctccagagacaactccaagaacatgctgtatctgcaaatgaatagcctgagagccgaggacacggccgtttattactgtgcgagagactcccacaaaccaccgacggtgacttgtactttgactactggggccagggaacccgggtcaccgtctcctcagcatcccccggaccagccccaaggtcttcccgctgagcctctgcagcaccctacgccagatgggaacgtggtcatcgccctgcctggtccagggcttcttcccccca +6362 JY8QFUQ01CJU11 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARNELPWDTREYYFDYW in-frame - gtctggattcaccttcagtagctacggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6363 JY8QFUQ01BY9TQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6364 JY8QFUQ01BR2DF productive (see comment) Homsap IGHV4-61*02 F (see comment) 686 79.19 175/221 nt 78.28 173/221 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [2.17.37.11] CARDRRRSIAGARHFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'C' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 117 in the user submitted sequence), (cause frameshift) gtctctggtggccccaccatcgatgatggtgatttgtggacctggatccggcagcccgccgggCaagggactggaatggatcggttatgtctatgatgggcggggcaccaactccaaccctccctccggagtcgcgttaccctgtcacaagacacctcaaacaatcagttcttcttgaggttgaagtctgtgaccgcctcagacacggccgtctattactgtgcgcgagaccgccgtaggtcgattgccggagcgagacactttgactcctggggccagggaatcctggtcaccgtcgccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6365 JY8QFUQ01AHB8A productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 901 90.41 198/219 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [2.17.38.11] CARADDYGDYPEFW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gcctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgcttagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6366 JY8QFUQ01CMM13 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 873 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] RAKDASRYYYNSYCDNW in-frame + Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatggccgaatcacaaactacgcggactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttattttcgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6367 JY8QFUQ01CZ0MI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggctttttccccca +6368 JY8QFUQ01BNM4N unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRGDRRDF## out-of-frame + Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcactttcagttccattaccatgaactggatgcgacaggctccagggaaggggctggagtacgtctcatcaattaataatgagggtggacacacactttacgcagactcagcgaagggccggttcaccatctccagagacaacgccgagaattcactgtatctgcaaatgaacaacctaagagtcgacgacacggctatatattactgtgtgagaggtgacaggcgtgacttctgggggccagggaaccctcgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc +6369 JY8QFUQ01CZQWE productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); cctccggattcaccGtttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtGgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +6370 JY8QFUQ01CFX1X No results +6371 JY8QFUQ01AYFQH productive Homsap IGHV3-48*01 F 1009 95.43 209/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 2 8 8 9 8.8.9 [2.17.38.11] CRGDPTQRDYG in-frame - gcctctgggttcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggctttcattcattactagtagtggtagtaccgtatactacgcagactctgtgaagggccgattcaccatctctagagacaatgtcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgccgcggtgaccctactcaacgtgactacgggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6372 JY8QFUQ01BWZ8Y No results +6373 JY8QFUQ01BA63F productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 795 85.98 184/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CGTSSRAWGADAFDIW in-frame - ctctgggctcagcgtcagtaactaccgcatgggctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagagatgatagtacagatcatgtagattccgtgaagggccgattcaccgtttcccgagacaattccaagaacacattgtaccttcagatgaacagtgtgacagccaaggacacggccgtttattattgtggaactagttcccgcgcctggggcgctgatgcctttgatatctggggccaggggacactggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6374 JY8QFUQ01DEHWK unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*05 F (see comment) 302 75.23 82/109 nt 8 10 X 8.10.X [1.17.X.X] null - No rearrangement found Low V-REGION identity (75,23% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcactttcagtgacgcctggatgagctgggtccgccagattccagggaaggggctggagtgggttggtcgtcgcatgcctggtccagggcttcttccccca +6375 JY8QFUQ01AF0GW No results +6376 JY8QFUQ01AIEDE productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F 330 88.24 75/85 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 X X 10 X.X.10 [X.X.28.11] CARLGQLALDYW in-frame + caccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgcctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6377 JY8QFUQ01ALUOL No results +6378 JY8QFUQ01AIDPR No results +6379 JY8QFUQ01CTQIN productive Homsap IGHV3-7*01 F 1013 96.33 210/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +6380 JY8QFUQ01BRXFV productive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGSSGFNDAYFDNW in-frame - ctccggattcacctttaacacttattggatgaactgggtccgccaggctccagggaagggactggagtgggtggccaacataaaccaagatgggagcaggagacactatgtggactctgtgatgggccgattcaccatctccagagacaacaccaaggactcactgtatctgcaaatggacagcgtgagagccgaagacacggctgtctattactgtgcgaggggatctagtggattcaacgacgcctattttgacaactggggccagggaaccctggccacagtatcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6381 JY8QFUQ01BSW67 productive Homsap IGHV3-66*02 F 926 92.56 199/215 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD6-13*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARDSPYSSGWSDGFDVW in-frame - cctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatatcagtggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaagaacacggtgtatcttcagatgaacagtctgagagctgaggacacggctgtgtattactgtgcgagagatagtccatatagcagcggctggtctgatggctttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6382 JY8QFUQ01C1QOH productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6383 JY8QFUQ01A1X52 productive Homsap IGHV3-48*02 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARVENYSDSGGSFDYW in-frame - cctctggattcaccttcagtagctatagcatgaattgggtccgccaggctccagggaagggactggagtgggtttcatacattagtggaagtagtaataccatgtactacgcagactctgtgaagggccgattcaccatctccagagacaatgcccagaattcactacatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagtggaaaattactctgatagtggtggttcgtttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggttttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +6384 JY8QFUQ01DTH5D productive (see comment) Homsap IGHV4-61*02 F 824 86.7 189/218 nt 86.24 188/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 10 6 14 10.6.14 [1.17.38.11] CARGSSGFNDAYFDNW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 102 in the user submitted sequence), (do not cause frameshift) tctctggtggccccatcagaggcggtggtttctactggacctggctccggcagtccgccgggaagggcctggagtggatcggacgtatttatgacagtggcagtgactacaatccttctctcaagagtcgagtcaccatgtcagtagacacgtccaagagccagttctccctgaggctgagttctgtggccgccgcagacacggctgtctattactgtgcgaggggatctagtggattcaacgacgcctattttgacaactggggccagggaaccctggccacagtatcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6385 JY8QFUQ01A73ZK productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt 93.78 211/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGXYYDSGGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctagcagcagtgttgTtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtnattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtctcgcctgcctggtccagggcttcttcccccagg +6386 JY8QFUQ01BBXZ8 No results +6387 JY8QFUQ01DSWTJ productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 830 86.43 191/221 nt 85.97 190/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 2 9 7 15 9.7.15 [2.17.38.11] CTSREHAFSGQFTGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'GTC' (3 nucleotides at position 27 to 29 in the user submitted sequence), (do not cause frameshift); atgtgtctggtgtctccgtcaccagcGTCagtcactggtggacctgggtccgccagcccccagggaagggactggagtggattggagaaatctattattatggcatcaccaatttcaacccgtccctcaagagtcgaatcagcatgtcagtggacgagtccaagaaccagttctccctgagactgacttctgttaccgccgcggacacggccgtttattattgtacgagtcgcgaacatgcttttagtggtcaattcacgggtgactactggggccagggaaccctgatgaccgtcacctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6388 JY8QFUQ01A7H7S No results +6389 JY8QFUQ01DMG6J productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +6390 JY8QFUQ01CY8KN unproductive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 968 93.58 204/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 9 7 X 9.7.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctctggtgactccatcagcaatgatagttggtggagttgggtccgccagcccccagggaaggggctggagtggattggggaaatctatcatactgggagcaccaactacaacccgtccctcaagagtcgagtcaccatatcactcgacaagtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacgcggccgtctattactgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6391 JY8QFUQ01A928N productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFHYW in-frame + tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttcactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6392 JY8QFUQ01C8K4D productive Homsap IGHV3-21*04 F, or Homsap IGHV3-48*04 F 823 87.04 188/216 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARVKYSSSWSSILDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagggacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgaggacacggccatatattactgtgcgagagtgaaatatagcagcagctggtcctcaatccttgactcctggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +6393 JY8QFUQ01BTH7J No results +6394 JY8QFUQ01AIAF1 productive Homsap IGHV1-2*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [0.17.38.11] CARGGTVTAGGPRIVFGYW in-frame + tggctacaccttcaccgactactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcaaccctgacggtggtagcacaaagtatgcacagaaatttcagggcagggtcgccgtgaccagggacacgtcaattagcacagcctacattgaggtgaccagactgacatctgacgacacggccgtgtattattgtgccagaggagggactgtgacagcaggtggtcctcgtattgtctttgggtactggggccagggaacgttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6395 JY8QFUQ01AFN53 productive (see comment) Homsap IGHV3-48*01 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-6*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAMRETSRSSLRHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagttccaatgccatgaactgggtccgccaggctccagggaagggctggaatggatttcatacattacaggtagcagtggtatcataaactacgcagactctgtgaagggccgattcaccgtctccagagacaatgccaagaattctctgtatctgcaaatgaacagcctgagcgccgacgacacggctgtctattactgtgcgatgcgagagaccagcaggtcgagtcttcgccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6396 JY8QFUQ01B8XV5 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARDRLTISALDY## out-of-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggtagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6397 JY8QFUQ01BMWKM productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 877 89.81 194/216 nt 88.43 191/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 35 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) cctcctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6398 JY8QFUQ01BO54Y productive (see comment) Homsap IGHV3-11*01 F (see comment) 788 84.86 185/218 nt 83.49 182/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [2.16.38.11] CARYRGSYYDYGGVDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift) acctctggcttcagattccgtgactactacatgacgtggtccgccaggctccagggaagggtcttgagtggctttcctccatcagcagcggtagtaataccatccactactcagactcggtgaggGggccgcttcaccatctccagggacaacaccagGgaactcagtggatctgcaaatgaatagtctgagagccgaagacacggccgtctattattgtgcgaggtacagaggcagttactacgactatggcggtgtggacgtctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6399 JY8QFUQ01DQTGB productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 869 88.99 194/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ggcctcctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6400 JY8QFUQ01AIE5T productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 881 90.23 194/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 9 8.7.9 [1.17.38.11] CARGGSYFWDW in-frame - tctctggtggctccaccaataataactactggacttggatccggcagcccccagggaagggaatggagtgggttgggtatgtcaattatgctgggaccaccaactacaacccctccctcaagagtcgagtcactatttcagtggactcgtccaagaaccagttctccctgagggtgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggcagctacttctgggactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6401 JY8QFUQ01CY8EN No results +6402 JY8QFUQ01C3NRO No results +6403 JY8QFUQ01BKJB5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) tctccggattcaccttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +6404 JY8QFUQ01BD7D1 No results +6405 JY8QFUQ01CI8VK productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 65 to 65 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'AG' (2 nucleotides at position 75 to 76 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggagggggctgGgagtgggtcAGtctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6406 JY8QFUQ01AXGGN productive Homsap IGHV4-61*06 ORF (see comment) 775 83.56 183/219 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD5-24*01 ORF 1 10 7 14 10.7.14 [1.17.38.11] CARGMATIKSVRFDPW in-frame + Low V-REGION identity (83,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacacgtccaagaaccagttctccctgcacttgacctctgtgaccgccgcagattcggccgtctattattgcgcgagagggatggccacaataaaatcggtccgattcgacccctggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtgggaactcagg +6407 JY8QFUQ01C8U6C productive Homsap IGHV3-7*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6408 JY8QFUQ01CUGM1 No results +6409 JY8QFUQ01BSWFL productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 6 10 9.6.10 [1.17.38.11] CASHGGKYFPQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggacaaatccatcatgtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6410 JY8QFUQ01DETBY productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt 8 7 9 8.7.9 [4.17.38.11] CARGGPHFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggcccccacttttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6411 JY8QFUQ01CQ336 No results +6412 JY8QFUQ01CO3PK unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-18*01 F 2 8 7 X 8.7.X [1.17.38.11] CASSVRGPAMAW##W out-of-frame + ctctggtggctccatcagtaattacttctggagctggatccggcagcccccagggaagggtctggagtggattgcgaatatctattacaatgggaacaccaactacaacccctccctcaagagtcgagtcaccatatctatagacacgtctaagaaccagttctccctgaaggtgaggtctgtgaccgctgcggacacggccgtgtattattgtgcgagctcagttagggggccagctatggcctgggaactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6413 JY8QFUQ01AJL3W No results +6414 JY8QFUQ01DJA9J productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 90 to 95 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6415 JY8QFUQ01B7WHM No results +6416 JY8QFUQ01C44RE productive (see comment) Homsap IGHV3-69-1*02 P (see comment) 701 80.93 174/215 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARTPCSGGNCYLRGHDLW in-frame + however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01C44RE ; 7 AA in Homsap_IGHV3-69-1*02), and low V-REGION identity (80,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctcgggattcaacttcaagtccaacaccatgaattgggtccgccaggctccagggaaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcgggtatttattattgtgcgcggacgccttgcagtggtggaaattgttaccttagaggccacgacctctggggccagggaacccaggtctccgtttccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccga +6417 JY8QFUQ01C43M3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6418 JY8QFUQ01CBCEN No results +6419 JY8QFUQ01B1OCM No results +6420 JY8QFUQ01B8EVU unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 870 88.64 195/220 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKEEGATGVYYVDH# out-of-frame - agcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactgggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6421 JY8QFUQ01CEIZC unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*03 F or Homsap IGHV4-34*04 F or Homsap IGHV4-34*06 F or Homsap IGHV4-34*07 F or Homsap IGHV4-34*09 F or Homsap IGHV4-34*10 F or Homsap IGHV4-34*12 F or Homsap IGHV4-34*13 F 97 58.44 45/77 nt 8 X X 8.X.X [1.16.X.X] null - No rearrangement found tatggtgggtccttcagtacttactactggacatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +6422 JY8QFUQ01AKM97 No results +6423 JY8QFUQ01CKYVH No results +6424 JY8QFUQ01CHV6I No results +6425 JY8QFUQ01DEKWC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ6*02 F 121 66.13 41/62 nt Homsap IGHD3-3*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKQTIFDYYYYGLDVW in-frame + ctctggattcatgtttagtagctttcccatggcctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctggggccaaggggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcctgctgagcctcgacagcaccccccgaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttccccca +6426 JY8QFUQ01DV24N productive (see comment) Homsap IGHV3-48*02 F 1026 97.24 211/217 nt 96.31 209/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD1-1*01 F 2 7 8 20 7.8.20 [1.17.38.11] CASGERKDYEVRRDYYHGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) cctctggactaccttcagcagctatagtatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatatattagtagtactagtagtaccataaAactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagtggggaaaggaaagactacgaagtacgacgggactactatcacggcatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6427 JY8QFUQ01A6TLD unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 719 85.28 168/197 nt 84.77 167/197 nt 8 2 X 8.2.X [1.17.37.X] null - No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) tctgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6428 JY8QFUQ01AC1CW No results +6429 JY8QFUQ01BHGLW No results +6430 JY8QFUQ01AJCQE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6431 JY8QFUQ01DJ81N unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 863 89.3 192/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [1.17.38.11] CTRELRVAAARDGVDIW# out-of-frame + cctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggagtgggtctcagtaatttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggcccaaagggacaatggtcaccgtctcttcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +6432 JY8QFUQ01AV8UD unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 96 95.24 20/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattcatcttcagtga +6433 JY8QFUQ01A3KTS No results +6434 JY8QFUQ01DQ766 No results +6435 JY8QFUQ01BXIFP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6436 JY8QFUQ01C8WEH No results +6437 JY8QFUQ01CJEBO productive (see comment) Homsap IGHV3-11*06 F, or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F 356 88.04 81/92 nt 86.96 80/92 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 X X 14 X.X.14 [X.X.30.11] CARSCTDGVCRFFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 79 of V-REGION: 4 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcaagacaacgccaagaactcactgtatctgcaaatgaacaacctgagagccgaggactcggctgtgtattactgtgcgagatcctgtactgatggtgtgtgtcgtttctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6438 JY8QFUQ01BQ8SE No results +6439 JY8QFUQ01BEMAB unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 868 89.35 193/216 nt 88.89 192/216 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaggggcgtggagtggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6440 JY8QFUQ01BP2SY unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 461 94.17 97/103 nt 8 8 X 8.8.X [1.17.X.X] null + No rearrangement found ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacata +6441 JY8QFUQ01B09EX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6442 JY8QFUQ01BHUFG productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcatctttgatgattttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +6443 JY8QFUQ01BIR27 unproductive Homsap IGHV4-61*01 F 947 92.31 204/221 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD6-6*01 F 3 10 7 X 10.7.X [1.17.38.11] CTRGGSTLMTAR## out-of-frame + tctctggtggctccatcagcggtagtactaactactggagctggattcggcagcccccagggaagggactggaattcattgggtatatctattccagtgggaggaccaactacaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccagttctccctgaggctggcgtctgtgaccgctgcggacacggccgtgtattactgtacgagggggggcagtacacttatgacagcccgtgggggacaggggacccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggggcttcttccccccgag +6444 JY8QFUQ01BNOAH productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccatggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6445 JY8QFUQ01A1FKO No results +6446 JY8QFUQ01CKCDG productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccg +6447 JY8QFUQ01CHUX9 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 855 88.48 192/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CTRVGTFNWFGPW in-frame + ctctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +6448 JY8QFUQ01ARTHF productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggGggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6449 JY8QFUQ01CE1ZB No results +6450 JY8QFUQ01CAGRS productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDYFDSW in-frame - tggatacaccttcaccgactacttcatacactggctgcgacaggcccctggacaacgacttgagtggatgggatggatcaaccctaagaatggtgacacaaagtatgcacagaactttcagggccgggtcaccatgaccagggacacgtccgtcagcaccatatatgtggaggtgagcagcctggaatctgacgacgcagccacttattactgtgcgagaggcttttatggtgactactttgactcctggggccagggagccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6451 JY8QFUQ01BCUEG No results +6452 JY8QFUQ01A2U68 No results +6453 JY8QFUQ01BZOVO productive (see comment) Homsap IGHV3-9*01 F 931 92.59 200/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'C' (1 nucleotides at position 144 to 144 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); tctggattcaccGtttcatgattataccatgGcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtGggtaacatagactatgcggcctctgtgaaGgggccgattcaccgtctCccagagacaacgccaataactccCctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6454 JY8QFUQ01BYP9J unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD6-25*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKSPLSV#W out-of-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +6455 JY8QFUQ01DMCLO No results +6456 JY8QFUQ01CRFYZ No results +6457 JY8QFUQ01CKJVN No results +6458 JY8QFUQ01CYHGF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6459 JY8QFUQ01A53H6 No results +6460 JY8QFUQ01CGXKQ unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARKRVPGGTFYG#DYW out-of-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatgggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6461 JY8QFUQ01DGCB3 unproductive (see comment) Homsap IGHV3-7*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-25*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGGW*R##LDYW out-of-frame + stop codons ctctggattcagctttagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggatggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt +6462 JY8QFUQ01B0B9Z No results +6463 JY8QFUQ01C6J6T unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 401 77.21 105/136 nt 76.47 104/136 nt 8 6 X 8.6.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (77,21% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) cctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6464 JY8QFUQ01BVQFR productive Homsap IGHV1-18*01 F 911 92.45 196/212 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 3 7 8 15 7.8.15 [X.17.38.11] CARDAQQWLVLQAFDYW in-frame - ttacaccctttgccagctatggtatcagttgggtgcgacaggcccctggacaagggcttgagtggatgggatgggtcagcgcttacaatggtcacacaaaatatgcacagaagctccagggcagagtcaccatgaccacagacacatccacggatacagcctacatggagctggagagcctgagatctgacgacacggccgtttattactgtgcgagagatgcgcagcagtggctcgtattacaggcatttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6465 JY8QFUQ01ALI3N productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 945 93.09 202/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +6466 JY8QFUQ01BLYLG productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6467 JY8QFUQ01AGCPF No results +6468 JY8QFUQ01BSHE2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame - cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6469 JY8QFUQ01B6V0U No results +6470 JY8QFUQ01AHFKE unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +6471 JY8QFUQ01AKC1Q No results +6472 JY8QFUQ01BL015 No results +6473 JY8QFUQ01BVA5Q productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 687 92.5 148/160 nt 91.88 147/160 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 2 X 7 13 X.7.13 [X.8.38.11] CARRGSYGSGSYYPW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); gaaggggctggagtggattgggagtatGcttttatactggggtcaccttctacaacccgtccctcaagagtcgagttaacatttccgtggacacgtccaagagccagttctccctgaggctgagctctgtgaccgccgcagacacggctgtgtatcactgtgcgagacgtggttcctatggttcggggagttattatccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +6474 JY8QFUQ01CVTI4 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaacttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6475 JY8QFUQ01BK81H productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 89.59 198/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgcgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +6476 JY8QFUQ01B5BQH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt 84.4 184/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [1.17.38.11] CTKTRVVLGITFPFYIYGLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); cctctggattcacgttcgacaactatgccatgagctgggtccgccaggcaccaggaaaggggctggagtgggtctccagtattagtggtaatggagaaattgtacaccacgcagacgccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgTtttttgcaaatgaatggagtgagagacgacgacacggccatttactactgtacgaaaacacgcgttgtgttgggaattacatttccgttctatatctatggtctggacgtctggggccaagggaccacggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6477 JY8QFUQ01DA6SD No results +6478 JY8QFUQ01A0PJV No results +6479 JY8QFUQ01CK56M No results +6480 JY8QFUQ01DO80W productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 11 8.8.11 [1.17.37.11] CNLHPYGDSSDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 160 in the user submitted sequence), (cause frameshift) ctctggactcaccttcagtcgcctctggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtatagatagtgatgggaataacataatctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaaacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtaaccttcatccctacggtgactcctccgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +6481 JY8QFUQ01BAON0 unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1009 95.89 210/219 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [2.17.38.11] CVRGDYGGDPRTLLRP#YGLDVW out-of-frame - gcctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgacccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6482 JY8QFUQ01AEDZX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 2 8 8 12 8.8.12 [1.17.38.11] CAKDQAVAGGFDYW in-frame - tctggatttacctttagctcctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtcgcaattattagtggtagtgatggtcgcacatactacgccgactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaataaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcaagcagtggctggaggatttgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6483 JY8QFUQ01APX8X unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 124 72.0 36/50 nt Homsap IGHD2-15*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDPRDYCSGGYCFVGAFDI## out-of-frame - tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctgggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6484 JY8QFUQ01CZGJ2 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARPLRATYGDYVNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); tctggattcaccttcgataactatgGgcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcaaaggatggaagtattgaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacaatttatctgcaaatgaacattgtgagggttgaggacacggctatgtattactgtgcgagaccccttcgggcaacttacggtgactacgtgaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6485 JY8QFUQ01CI9GM productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDWPSSGWSHFEAW in-frame + ctctggattcacctttgatgagcatgccatgcactgggtccggcaagttccggggaagggcctggagtgggtctctggtgttacttggaatagtggtgtcatagactatgcggactctgtgaagggccgattcaccatctccagagacaacgccaggaattccctgtatctacaaatgaacagtctgagaactgatgacacggccttctatttctgtgcaaaagattggccgagcagcggctggtcccattttgaggcttggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6486 JY8QFUQ01CJTG8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 8 8 8.8.8 [1.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6487 JY8QFUQ01DKV4A unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found ctctggattcatcttcagtagctactggatgcactggg +6488 JY8QFUQ01DAV5Y No results +6489 JY8QFUQ01C0MUL productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*02 F or Homsap IGHV3-33*06 F 908 91.63 197/215 nt 90.7 195/215 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD3-3*01 F 3 8 7 22 8.7.22 [1.16.38.11] CARDFLAPNRFGVFDYYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 89 in the user submitted sequence), (cause frameshift) gtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcagggtctggaatggttggcaatgatatggtatgtggaaataaaaaatactacgcagactccgcgacgggccgattcaccatctccagagacaattctgagtacacgctgtctcttcaaatgaacagcctgagagtcgaggacacggctgtctattactgtgcgagggatttcttagccccgaatcgttttggagtgtttgactactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6490 JY8QFUQ01DEFYH unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 800 86.05 185/215 nt 85.12 183/215 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD4-17*01 F 3 7 8 X 7.8.X [1.16.38.11] CARDAGNTWPNYFDH#W out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) ctctggattcagcttttcaattatggcatgaactgggtccgccaggctccagggaggggctggagtgggtcgcatttattagcggtgctggtgaaaatacttactacgcagactccgtgaagggccgattcgccatctccagagacgattcgagggacacactgtatctccaaatgagcagcctgagagccgaggactcggccctctattattgtgcgcgagatgcgggcaacacctggcccaactactttgaccacgtggggccagggaaccctggtcaccgtctcctcgggtgagtcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +6491 JY8QFUQ01CDVK0 unproductive (see comment) Homsap IGHV4-61*02 F 925 90.99 202/222 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 X 10.7.X [2.17.38.11] CAREK**SV#NWFDPW out-of-frame + stop codons gtctctggtgactccatcaccagtggtaattattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggatcaccaactacaatccctccctcaagagtcgagtcaccatactattagacacgtccagcaaccggttctccctgaagctcagctctgtgaccgccgcagacacggccgtgtattactgtgctagagaaaagtagtgatccgtcccaattggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6492 JY8QFUQ01BQZBN No results +6493 JY8QFUQ01CNUJW No results +6494 JY8QFUQ01COJDW productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 927 92.17 200/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6495 JY8QFUQ01C4X4D productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 281 81.4 70/86 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame - Low V-REGION identity (81,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +6496 JY8QFUQ01AKK7C productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6497 JY8QFUQ01CRETZ productive Homsap IGHV3-7*01 F 847 87.67 192/219 nt Homsap IGHJ6*02 F (see comment) 219 92.16 47/51 nt 8 8 8 8.8.8 [2.17.38.11] CARSYGMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ggctctgggttcttctttggtagttattggatgacctgggtccgccaggctccagggaagggactagagtggttggccaacctaaagcacgatggcagtggaatatcctatgcggactctgtgaagggccggttcaccatttccagagacaacgccaagaacacagtgtatctgcaaatgaatagcctgagagtcgaagacacggctgtctattattgtgcgagaagttacggtatggacgtctggggccacgggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6498 JY8QFUQ01DQXTY productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 996 95.0 209/220 nt 94.55 208/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [2.17.38.11] CARPGVGASSFIDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); gggttctggatacagcttaccggcctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaCccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6499 JY8QFUQ01AIISH productive Homsap IGHV3-11*01 F 110 61.04 47/77 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 X X 8 X.X.8 [X.X.25.11] CTRRGFMDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tccggattcactttagtgactattggatgagttggatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6500 JY8QFUQ01BI3YG No results +6501 JY8QFUQ01BTU7H productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6502 JY8QFUQ01CCMJ5 productive (see comment) Homsap IGHV4-61*02 F (see comment) 714 80.27 179/223 nt 79.37 177/223 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 10 7 16 10.7.16 [2.17.38.11] CARERGTAVGGARELDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 38 of V-REGION: 'A' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift); gtgtctggtgggccccgtcagcagtgatggttactAcctggacctggatccgccagcccgccgggcagggactggagtgggtcggacgtgtttccagtcgtgggggAgaccgactacagttcctccctcaagagccgaatcaccatgtcaatagacacgtctaagaaccagttctccctgaggttgaactctgtgaccgccgcagacacggccctatactactgtgcgagagagcgcggtactgcggttggcggagcgagagaacttgactcctggggccagggatcccaggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6503 JY8QFUQ01DB5QJ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 123 68.42 39/57 nt 8 X X 8.X.X [1.9.X.X] null - No rearrangement found ctctggattcacctttagtaaccattggatgaactgggtccagggcttcttccccca +6504 JY8QFUQ01A451K productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaaggggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6505 JY8QFUQ01BLC8W unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 158 91.89 34/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcacctttaacagccatgccatgagttgg +6506 JY8QFUQ01AKJR2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1013 96.33 210/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*03 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6507 JY8QFUQ01CRCUI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6508 JY8QFUQ01BGY05 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1037 96.83 214/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaggagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6509 JY8QFUQ01CFF3G unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6510 JY8QFUQ01ARJM3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 690 79.55 175/220 nt 79.09 174/220 nt Homsap IGHJ6*02 F (see comment) 148 70.97 44/62 nt Homsap IGHD5-24*01 ORF 3 8 8 15 8.8.15 [2.17.38.11] CASGGNAYITRRGLEVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 88 of V-REGION: 'A' (1 nucleotides at position 170 to 170 in the user submitted sequence), (cause frameshift); agcttccggcttcaccctcagtaaacactggatgcattgggtccgccagccttcagggaagggcctggagtttgtcgcgcgtctgagtaatgatggatataccacaagttatgcagactccgtgcagggccgcttcactatctccagagacgccgccgcgaacgcgctgAtttttgcagttgaccggtctgagagccgacgacacgggtgtctattactgtgcaagtgggggaaatgcctacatcacgcggcgtggtctggaggtctggggccgggggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6511 JY8QFUQ01DDZNR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 821 85.97 190/221 nt 84.62 187/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKGIVGASMQADWFHPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'AT' (2 nucleotides at position 18 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); ggcctcctggattcgtcATttgggcgactatgcgatgagGctgggtccggcaggctccagggaTgggggctggagtgggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +6512 JY8QFUQ01A2EFK No results +6513 JY8QFUQ01DE7ZV unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.37.11] CVSDLAGQKGF# out-of-frame + in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6514 JY8QFUQ01CYBAX productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1017 96.77 210/217 nt 96.31 209/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 7 10 8.7.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6515 JY8QFUQ01AFPO8 No results +6516 JY8QFUQ01CXD2W No results +6517 JY8QFUQ01AVYZP productive Homsap IGHV1-3*01 F 903 91.59 196/214 nt Homsap IGHJ4*02 F (see comment) 231 97.92 47/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDGEPLGGDYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggatacaccttcacttcttatgctgtaaactgggtgcgccaggctcccggacaaaggcttgagtggatgggatggatcaacgctggcacgggtaacacaaaatattcacagaagtttcagggcagagtcaccattaccagggacacatccgcggacacagtcttcatggagctgagcagtctaagatctgaagacacggctgtgtattattgtgcgagagatggggagccactgggaggcgactactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6518 JY8QFUQ01DF7OW No results +6519 JY8QFUQ01BZEHF No results +6520 JY8QFUQ01BCJD8 unknown (see comment) Homsap IGHV3-74*03 F 136 52.36 100/191 nt 8 8 X 8.8.X [1.17.29.X] null + No rearrangement found stop codons ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggcaacgtggtcgtcgcatgcctggtccagggcttcttcccccga +6521 JY8QFUQ01AH7K3 No results +6522 JY8QFUQ01B48P7 productive (see comment) Homsap IGHV3-11*01 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6523 JY8QFUQ01B69I7 unknown (see comment) Homsap IGHV1-2*02 F 503 86.47 115/133 nt 85.71 114/133 nt 8 8 X 8.8.X [0.17.11.X] null + No rearrangement found in FR2-IMGT at codon 39 of V-REGION: 'T' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); tggatacattttcaccggctactattTtacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaacc +6524 JY8QFUQ01ANOND productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +6525 JY8QFUQ01AC0IK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 847 87.67 192/219 nt 87.21 191/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDLYGADDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gcctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaAaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6526 JY8QFUQ01AGAIC No results +6527 JY8QFUQ01CDEJX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6528 JY8QFUQ01BL6W5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6529 JY8QFUQ01BV1R6 unknown (see comment) Homsap IGHV3-49*01 F, or Homsap IGHV3-49*03 F or Homsap IGHV3-49*05 F 88 51.91 68/131 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons ttctggattcacctttggtgactatgctatgagctggttccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +6530 JY8QFUQ01DAHNB No results +6531 JY8QFUQ01DH31Z No results +6532 JY8QFUQ01AZL76 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [2.17.38.11] CARDRLTISALDYW in-frame - gcctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6533 JY8QFUQ01AE2O7 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 118 50.72 106/209 nt 8 8 X 8.8.X [1.17.35.X] null + No rearrangement found ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6534 JY8QFUQ01CGEWF productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAREGGSGPGSSEDYFDYW in-frame + ctctggattcaccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaatggtgcttacatatactacgcagactcaatggagggccgattcaccatctccagagacaacgccaggaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgcgagagggggggtcggggccaggttcgtcggaagactactttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6535 JY8QFUQ01C0UL8 productive Homsap IGHV3-66*02 F 858 89.25 191/214 nt Homsap IGHJ1*01 F 206 88.46 46/52 nt Homsap IGHD6-19*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAAVGVGSAVSFQYW in-frame - ctctggcttcaccgtcaataacaactacatgggctgggtccgccaggctccagggaaggggctggagtgggtctcgattatttattacggtggaaccacatattacgctgactccgtgaagggccgattcaccatctctagagacacctccaagaacacgttatttcttcaaatgaataccctaagaggtgaggacacggctgtgtactactgtgcggcagtcggagtgggaagtgcagtctccttccaatactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6536 JY8QFUQ01DTB26 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6537 JY8QFUQ01CIZB1 No results +6538 JY8QFUQ01BWGSR unknown (see comment) Homsap IGHV3-7*01 F 1035 97.7 212/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga +6539 JY8QFUQ01A6T5J productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAKDFYYGCDYW in-frame + tctctggattcaacttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagtcattgcatacaatggaggaaatatatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaaggataccctgtacttgcacatgaccagtctgagacctgatgacacggccatgtattactgtgcgaaagacttttattatggttgcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +6540 JY8QFUQ01CDHWB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 928 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 79 to 81 in the user submitted sequence), (do not cause frameshift); gcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6541 JY8QFUQ01B3X75 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6542 JY8QFUQ01C9Q5C productive Homsap IGHV4-31*06 F 1001 95.0 209/220 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 10 7 15 10.7.15 [1.17.38.11] CARVIIDDSGGNYFDYW in-frame + tctctggtgcctccatcagcagtggtatttactactggagctggatccgccagcacccaggggagggcctggagtggattgggtacatctctgacagtgggagcacctactacaacccgtccctcaagagtcggtttaccgtatcagtggacacgtctaagaaccagttctctttgaagctgagctctgtgactgccgcggacacggccgtgtattactgtgcgagagtaataatagatgactccggtggtaactactttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6543 JY8QFUQ01CMLXH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 904 91.2 197/216 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKDKWYYDSSGYQYYLDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctggatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagacaaatggtactatgatagtagtggttatcaatactaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6544 JY8QFUQ01CAWBX No results +6545 JY8QFUQ01DBL7Y productive (see comment) Homsap IGHV2-5*02 F 1044 92.21 225/244 nt 91.8 224/244 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-2*01 F 2 10 7 14 10.7.14 [9.17.38.11] CAHISASISTSCHDLW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 154 to 154 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcagcttctctgggttctcactcagcactgttggagtgggtgtgggctgggtccgtcagcccccaggaaaggccctggagtggcttgcactcatttattgggatgacgataagcgttacagttcatctctaaaaagGtcgcctcaccatcaccggggacactcccaaaaaccaggtggtcctgacaatgaccaacatggaccctgtggacacagccacatattattgtgcacacatctcagcgagtattagcaccagctgccatgacctctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttctt +6546 JY8QFUQ01BK7D8 No results +6547 JY8QFUQ01BWUPM No results +6548 JY8QFUQ01BAIEJ No results +6549 JY8QFUQ01CZH0L productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.16.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggagggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6550 JY8QFUQ01DAFG7 No results +6551 JY8QFUQ01BO9QZ productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [2.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) tgttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6552 JY8QFUQ01BR2I0 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6553 JY8QFUQ01C42VY productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +6554 JY8QFUQ01BB1TT No results +6555 JY8QFUQ01AG2W0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6556 JY8QFUQ01AC4B0 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P (see comment) 470 68.87 146/212 nt 68.4 145/212 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [0.17.38.X] null - Rearranged sequence but no junction found however the closest V is a pseudogene Low V-REGION identity (68,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT at codon 64 of V-REGION: 'CAA' (3 nucleotides at position 93 to 95 in the user submitted sequence), (do not cause frameshift); ctggattaaccctcagtgaccactacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtCAAaacatatactacagagactcagtgcggggccgattcaccatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6557 JY8QFUQ01BKRAL unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 940 93.06 201/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + stop codons tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgtaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6558 JY8QFUQ01BX7QA productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 872 89.77 193/215 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + tatatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaatagtcgagtcatcatatcgatagacacgtccaagaaccaggtctccctgaagctcttctctgtgaccgccgcggacacgggtgtgtactattgtgcgaggcccacgtatagtagcggccgggacgcctttgatacctggggccaagggacgacggtcaccgtctcatcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6559 JY8QFUQ01DE0Z1 No results +6560 JY8QFUQ01C6CJJ No results +6561 JY8QFUQ01AQQPC productive (see comment) Homsap IGHV2-5*02 F, or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F 900 85.66 209/244 nt 85.25 208/244 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 3 10 7 11 10.7.11 [9.17.38.11] CAHFGPQEHFDFW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 93 of V-REGION: 'CG' (2 nucleotides at position 209 to 210 in the user submitted sequence), (cause frameshift); gaccctcaccctgacctgcgacttctctggattctcactcagcaccaatggaatgggtgtgggttggatccgccagcccccgggagaggccccagactggctcgctctcatttattgggatgatgataagcgataccggccatccctagagagtagactcaccatcaccaaggacatctccacaaaccaggtggtccttagaatgaccCGacatggggccctgcagacacagccacatatttctgtgcacactttggaccacaggagcacttcgacttttggggccagggaatcctggtcactgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6562 JY8QFUQ01BCMDL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 405 77.78 105/135 nt 76.3 103/135 nt 7 6 X 7.6.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (77,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 97 in the user submitted sequence), (cause frameshift) cctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6563 JY8QFUQ01C97NB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactcag +6564 JY8QFUQ01DEMSU unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 921 92.52 198/214 nt 90.65 194/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 2 8 7 X 8.7.X [1.17.37.11] CARFGPTYST#DYW out-of-frame - stop codons in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 92 of V-REGION: 'T' (1 nucleotides at position 180 to 180 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 86 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 206 in the user submitted sequence), (cause frameshift) tctggattcacctttaccGaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtgtagtggtgaaactacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaaTcagtctgagagccgaggacacggccattattactgtgcgagattcggacctacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6565 JY8QFUQ01DIJF9 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt 86.7 189/218 nt Homsap IGHJ6*02 F (see comment) 139 69.35 43/62 nt Homsap IGHD3-3*01 F 3 8 8 12 8.8.12 [1.17.38.11] CAKSPIFGVEKDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcagctttagtagctatggcatgagttgggtccgccaggctccagggaagggactggagtgggtctccgctattgatactggcggtgatcttacgttccacgttgactccgtgaagggccgcttcaccatctccagggacaattccaagaatacgctgtatctgcaaatgagcggcctgagagtcgaagacacggccgtatattactgtgcgaaatctccgatttttggagtggagaaggacgtctggggccaagggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6566 JY8QFUQ01AH82H unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcacctttaccaactatgccatgacctgggtccgccaggctccagggaaggggctggaatgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6567 JY8QFUQ01BA91L No results +6568 JY8QFUQ01DF5O3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 665 83.51 157/188 nt 82.98 156/188 nt Homsap IGHJ1*01 F 116 69.23 36/52 nt Homsap IGHD4-11*01 ORF 2 X 8 6 X.8.6 [X.16.38.11] DSRNPRVG in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,51% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tgagtggggtccgccaggctccagggaaggggctggagtgggtctcagGgcttttgtggaagtgctcctaccacacactacgcagactccgtgaagggccggttcagcatctccagagacctctccaagaatgttctgtttctgcaaacgagcagcctgagagccgaggacacgaccgttttttctgactccagaaatcccagggtagggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtccgtggaactcag +6569 JY8QFUQ01DXA7M productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6570 JY8QFUQ01BG3CJ No results +6571 JY8QFUQ01A5CAD unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 555 78.14 143/183 nt 8 8 X 8.8.X [1.17.26.X] null - No rearrangement found Low V-REGION identity (78,14% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaacgccgaaccggtgacggtgtcgtggaactcag +6572 JY8QFUQ01AZ70S unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAGSGRDPYGINV## out-of-frame - cctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6573 JY8QFUQ01BALFI productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1027 96.8 212/219 nt 95.43 209/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [2.17.38.11] CARPGVGASSFIDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); ggttctggatacagctttaccggcCtactggatcggctgggtgcgccagatgcccgggaaaggcctggagCtgggtggcgatcatctatcctggtgactctgaaaCccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6574 JY8QFUQ01B5K4J unknown (see comment) Homsap IGHV5-51*05 F 167 53.37 111/208 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found stop codons gtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6575 JY8QFUQ01AYW1V productive (see comment) Homsap IGHV3-33*03 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctcccagccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6576 JY8QFUQ01CM8PU No results +6577 JY8QFUQ01B8N16 unproductive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 918 91.71 199/217 nt Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPGGNCLL*WW*#CYDPW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcatctttgatgattttggcatgaattgggtccgccaagctccagggaaggggctggagtgggtcgctggtatcagttggaatggtggcaaagcaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggaattgcctattgtagtggtggtagctgctacgacccctggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6578 JY8QFUQ01DMNTN unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F or Homsap IGHV4-61*02 F 148 62.92 56/89 nt 10 1 X 10.1.X [1.17.X.X] null - No rearrangement found stop codons tctctggtggctccatcagcagcagtagttactactcgacctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6579 JY8QFUQ01A701H productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 802 85.39 187/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARLAMLRGVPTWFDPW in-frame - gcctctggattcgacctcactacctattccatgagctgggtccgccagactccagggatggggctggagtgggtctcttcaataagtagcaagagtaataccgtctcctacgcagactcagtgaagggccgattcaccatctccaaagacaacgccaaaaacttattgtttttgcaaatggacagcctgagagacgaggacacggctatttattactgtgcgagacttgcaatgcttcggggagtccccacctggttcgacccctggggccagggagccctagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6580 JY8QFUQ01CO7PU No results +6581 JY8QFUQ01CJJI3 No results +6582 JY8QFUQ01DEE6N No results +6583 JY8QFUQ01B6475 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKDKWYYDSSGYQYYLDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcccctttagcaactatgacatgaattgggtccgccaggctccagggaaggggctggagtgggtctccggtattagtggtagtggcggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctggatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagacaaatggtactatgatagtagtggttatcaatactaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6584 JY8QFUQ01C9UQH productive Homsap IGHV3-7*01 F 846 88.02 191/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRDRPGGWALDYW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +6585 JY8QFUQ01CMGM0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 2 8 8 17 8.8.17 [1.17.37.11] CAKDWSIGARFPQGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 76 of V-REGION: 2 nucleotides (from position 131 in the user submitted sequence), (cause frameshift) ctctggattcacctttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctctttcattagtggtaatggtggtagcatagactacgcagactccgtgaagggccggcaccatctccagagacaattccaagaatacgctgtatctgcaaatgaatagtctgagagccgaggacacggccgtctattactgtgcgaaagattggagtataggagcacgtttcccccaaggagcttttgatatctggggccaaggggaattggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtctagggcttcttccccca +6586 JY8QFUQ01DFGPB unproductive Homsap IGHV4-61*02 F 884 89.14 197/221 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD5-24*01 ORF 1 10 7 X 10.7.X [1.17.38.11] CARDFGGSYNLVAY## out-of-frame + tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6587 JY8QFUQ01CO7VN productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6588 JY8QFUQ01CR24N productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6589 JY8QFUQ01A3HEN unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD4-23*01 ORF 1 8 8 16 8.8.16 [0.17.38.11] CAKITPL*QEWSIIPTTG in-frame - stop codons in FR2-IMGT at codon 52 of V-REGION: 'T' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); ctctggtcatttttggccactataccatgagctgggtccgccaggctccagggaaggggctggagtTgggtctcagctattggtaatagtggtgatattacatactacgcagactccgcgaggggccggttcaccatctccagagacaattcccagaacacactgtatctgcaagtgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaataacccccctatgacaggagtggtccattataccgactactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6590 JY8QFUQ01DNSYR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 886 90.28 195/216 nt 89.35 193/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 66 of V-REGION: 'G' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'C' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactgatagcggacgcagcacatGactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaagCaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6591 JY8QFUQ01BJD1H No results +6592 JY8QFUQ01BCUAN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 660 90.57 144/159 nt 89.94 143/159 nt 8 8 X 8.8.X [1.17.19.X] null + No rearrangement found in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 76 to 78 in the user submitted sequence), (do not cause frameshift); tcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaac +6593 JY8QFUQ01C7ZZV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 8 8 9 8.8.9 [1.17.38.11] CAKEEVPNDYW in-frame + ctctggattcacctttagcaatgctgccatgacgtgggtccgccaggctccagggaaggggctagagtgggtctcaggtattagtattagtggtgatagaacatattacgcagactccgtgaagggccggttcaccatctctagagacaattccaagaataccgtgtatctgcaaatgaacagcctgagagccgaggacacggccatatattattgtgcgaaagaggaggtcccgaatgattattggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttcccccag +6594 JY8QFUQ01A78VU unknown (see comment) Homsap IGHV3-30*05 F, or Homsap IGHV3-30*13 F or Homsap IGHV3-74*01 F or Homsap IGHV3-74*02 F 129 55.3 73/132 nt 8 7 X 8.7.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcaacgtcagtggatactggatgcactgggtccgccaagtgccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +6595 JY8QFUQ01A3VO9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6596 JY8QFUQ01DUA6P No results +6597 JY8QFUQ01BDEJ4 productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6598 JY8QFUQ01BADHK productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaactca +6599 JY8QFUQ01B3JLF productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 785 84.16 186/221 nt 83.71 185/221 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFESW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); tttccggtgactccatcaccagtactaattattactggggctgggtccgccagtccccagggaagggtctggagtggattggaagtgtctattatCggggggacccagtacctcaacccgtctctccacaatcgagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtcttttggagtgataattgttaactactttgagtcctggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6600 JY8QFUQ01BE8EN No results +6601 JY8QFUQ01BSDXC productive Homsap IGHV1-69*04 F, or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69*10 F or Homsap IGHV1-69*14 F 822 87.38 187/214 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [0.17.38.11] CAIPFSSSSAWFDPW in-frame + tggaggcaccttcagcagctatgtcatcagctggctgcgacaggcccctggacaagggcttgagtggatgggacatgtcattcctatgtttggtgtatctaacctcgcgcagaggttccagggcagagtcacaataaccgcggacacatccacgaccacagcctacatggaggtgaccaggctgagatctgaagacacggccgtctattattgtgccataccattcagcagctcgtcggcctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6602 JY8QFUQ01ANECA productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 641 89.87 142/158 nt 89.24 141/158 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 X 7 13 X.7.13 [X.7.38.11] CVREVTGVWDWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); aggggctggagtggattggAcaaaatccatcatggtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6603 JY8QFUQ01B33A5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1003 96.3 208/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CILLYYDSRGVFSTDYW in-frame + tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggcgtgggtctcacgtattaaaagtgatggcagtggcacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagagcacgctgtttctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtatactgctttactatgatagtagaggtgtcttttcaaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggcatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6604 JY8QFUQ01ATQ7U No results +6605 JY8QFUQ01BJ8VI productive (see comment) Homsap IGHV3-11*01 F (see comment) 681 79.09 174/220 nt 78.18 172/220 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-25*01 F 2 8 8 11 8.8.11 [2.17.38.11] CVRDRSRGIADPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); gacgtctggattcaccttcactgactattgGgatgagttgggtgcgcctgAgccccagggaagggtctagaatgggtttcgttcataagtggaagtggcaatagtgtctggtatgcagactctgtgaagggccgattcattatctccagagacaacgccaaaaatttagtcattttggacatgaacagcctgagagtcgaggactcggccatgtattattgtgtgagagaccgcagcaggggaatagcagatccttggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6606 JY8QFUQ01DPKOD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 495 69.59 151/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] VHT#AFW out-of-frame + Low V-REGION identity (69,59% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgaggacaactttggtgaacacgccatgggatggatccgccagtctccgggggggattcttcagtgggtcgctgcgatcagtggtgacggactgacggcgtttcacgcagacttcgtggagggtcgattcagcatctccagagacaatcccataaacactctttttctgcaaatgaacagcctcagagtcgaagattcgggtgtctattttgtgcacacactgccttctggggccggggatcccgggtcaccgtctcctccgcatccccgaccagccccgaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6607 JY8QFUQ01BVMAB productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - gcctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +6608 JY8QFUQ01AFIEW productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6609 JY8QFUQ01CQJP3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6610 JY8QFUQ01BDYFI productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 876 89.77 193/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccntgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6611 JY8QFUQ01ADM49 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6612 JY8QFUQ01AQAV9 unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 696 78.92 176/223 nt 78.48 175/223 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 10 X 8.10.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (78,92% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); ctctggattcactgtcaataacgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgatggcgggacagcagactacgctccatttgtggacgacagattcaccatttcaacagatgattcaaaaaaGcacgttgtatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6613 JY8QFUQ01B0M8W productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 951 92.73 204/220 nt 91.82 202/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 2 10 7 12 10.7.12 [1.16.38.11] CARSRTFYGSANYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 27 of V-REGION: 'C' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift) tctctggCtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaaggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6614 JY8QFUQ01CXPI0 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 639 76.96 167/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (76,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6615 JY8QFUQ01B6QWG productive (see comment) Homsap IGHV4-39*03 F 893 89.55 197/220 nt 88.64 195/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'TGG' (3 nucleotides at position 73 to 75 in the user submitted sequence), (do not cause frameshift); tctccggtggctccatcaacagtagaaAattattattggggctggatccgccagccccccagggaagggtttTGGgagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6616 JY8QFUQ01CZRM7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 18 8.8.18 [1.17.38.11] CVRESGDYGGKYSKSYFDYW in-frame + ctctggattcactttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatcaattactagaagttctagttatatgtcctacgcagactcagtgaagggccgattcaccatctccagagacaatgccgagaattcactgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgtgagagaatcgggtgactacggtggtaaatatagcaagtcatactttgactattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6617 JY8QFUQ01BVSZ2 No results +6618 JY8QFUQ01C1NJL productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.38.11] CSRLLEEW in-frame - cctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6619 JY8QFUQ01C4MHW productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'A' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggAactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6620 JY8QFUQ01DJCMJ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [1.17.38.11] CACYFDSNGFFDYW in-frame + ttctggatacgtctttccctcctactggatcgcctgggtgcgccagatgcccggtaaaggcctggagtggctgggaaccatctatcccggcgactctgacaccacatacagcccgtcattccaaggccaggtcaccatgtcagtcgacacgtccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacagcgccatttactattgtgcgtgttattttgatagtaatggtttctttgactactggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6621 JY8QFUQ01BMLW8 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 389 75.54 105/139 nt 8 8 X 8.8.X [1.17.11.X] null - No rearrangement found Low V-REGION identity (75,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6622 JY8QFUQ01A5LN2 productive Homsap IGHV3-33*02 F, or Homsap IGHV3-33*03 F 148 65.43 53/81 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 X X 14 X.X.14 [X.X.27.11] CATDDSNGWDEVADYW in-frame - gcctctggattcaccttcagctcccattggatgagctggatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagacagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6623 JY8QFUQ01A11FZ No results +6624 JY8QFUQ01DN99N productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 813 86.92 186/214 nt 86.45 185/214 nt Homsap IGHJ3*01 F (see comment) 164 80.0 40/50 nt Homsap IGHD3-10*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAKESLFGESSHTTFDDW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) ctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggtttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctgttcggggagtcatctcatacnacttttgatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6625 JY8QFUQ01C7VAT unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame + ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +6626 JY8QFUQ01CV39H unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 867 87.44 195/223 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD6-19*01 F 3 10 7 X 10.7.X [2.17.38.11] CTNDHSMAVSAKHAFDV## out-of-frame - gtcctctggtgcctccatgagcagtagtgcatactactggggctgggtccgccagacccccgggaaggggccggagtggattgggagtgtctactatggtgggagcacctactacaacccgtccctcaagagtcgggcctccatttctgtcgacacgtccaggaacgagttctccctgaggctgaactctgtgaccgccacagacacggctatgtattactgcacgaacgaccattcaatggcagtctctgctaagcatgcttttgatgtttgggggtccagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +6627 JY8QFUQ01AE04Y unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 405 89.9 89/99 nt 8 6 X 8.6.X [1.17.X.X] null + No rearrangement found ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagggtgttgac +6628 JY8QFUQ01BQI8F productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 863 89.3 192/215 nt 88.37 190/215 nt Homsap IGHJ1*01 F 215 90.38 47/52 nt Homsap IGHD5-12*01 F 3 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); cctctgacttaaTcggtcagtgacaattaGcatgagttgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacggttcccagaacacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtatttttgtgcgagtggtggttattcgggctcgggtgaatatttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6629 JY8QFUQ01A0EFI No results +6630 JY8QFUQ01CZVE5 No results +6631 JY8QFUQ01AGDXX No results +6632 JY8QFUQ01CBZ9Q No results +6633 JY8QFUQ01DCG8G productive (see comment) Homsap IGHV3-48*04 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.16.37.11] CAKDGARGGGSCFNSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 90 of V-REGION: 1 nucleotides (from position 176 in the user submitted sequence), (cause frameshift) acctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaagggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaatgagtggcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6634 JY8QFUQ01AWIFY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - tctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6635 JY8QFUQ01B2ARX productive Homsap IGHV3-33*03 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARSDLSMVRDLDYW in-frame + gtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatgatttggtatgatggaagccttacatattatgaagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgctgtttctgcaaatgaatagcctgagagtcgaggacacggctctgtattactgtgcgagatccgacctctctatggttagagatcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6636 JY8QFUQ01BVN7Z unknown (see comment) Homsap IGHV4-61*01 F 978 94.09 207/220 nt 93.64 206/220 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found in FR3-IMGT at codon 67 of V-REGION: 'TATAATCCCCTG' (12 nucleotides at position 110 to 121 in the user submitted sequence), (do not cause frameshift); ctctggtggctccgtcagcagagatatttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatgtatcacagagggaacactaagTATAATCCCCTGtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +6637 JY8QFUQ01DEBDW productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaagggactacttccccgaaccggtgacggtgtcgtggaactc +6638 JY8QFUQ01DQT4B productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [2.17.38.11] CVRYDYSRLHRSNYFGPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); gtctctggattcaccttcatcagttatggcatgagttgggtccgccaggTttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc +6639 JY8QFUQ01CF2CB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6640 JY8QFUQ01B3AB2 unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 945 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found gtctggcttcacgttcagtagttatggcatgcaatgggtccgccaggctccaggcaaggggctggagtgggtggcagttatttggtatgatggaagtaataaatattatgcagactccgtgaagggccgattcgacatctccagagacaattccaagaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatgtaccattgtgcgagaggcggcggtgcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +6641 JY8QFUQ01DM1N1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); cctctggattcacctttaccaactatggGcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccaCggcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctcgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +6642 JY8QFUQ01AYRUD productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6643 JY8QFUQ01A1QLN productive (see comment) Homsap IGHV3-13*01 F 971 94.88 204/215 nt 94.42 203/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.37.11] CARGSSKAYNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 193 in the user submitted sequence), (cause frameshift) gcctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccgggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6644 JY8QFUQ01A1K37 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6645 JY8QFUQ01C9F82 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + stop codons Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); ctccggattcagtttcagtacttataacatgaattgggtccgctaggctccagggaaggggctggagtgggtctcatccatggGgtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6646 JY8QFUQ01AM701 productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARELGGSGTCGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccaggcactatatgcactgggtgcgacaggCcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggggcagagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +6647 JY8QFUQ01A55QU productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame + ctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6648 JY8QFUQ01AQRKK unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 400 77.61 104/134 nt 76.12 102/134 nt 7 6 X 7.6.X [1.17.12.X] null + No rearrangement found Low V-REGION identity (77,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6649 JY8QFUQ01BPRTG unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-NL1*01 F 91 54.46 55/101 nt 8 8 X 8.8.X [0.17.X.X] null + No rearrangement found stop codons tggattcaccttcagtcgttatagcatgaactgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6650 JY8QFUQ01DGQLY No results +6651 JY8QFUQ01BL3MM unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 999 95.85 208/217 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD6-6*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRSEYSSSNWFDP# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgaccctgggccagggaaccctggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6652 JY8QFUQ01APL75 productive Homsap IGHV3-7*01 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - cctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6653 JY8QFUQ01DTC10 productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 806 85.78 187/218 nt 85.32 186/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [2.16.38.11] CVRDLNWSFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 72 in the user submitted sequence), (cause frameshift) gcctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggattcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6654 JY8QFUQ01ABFKK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVSDLAGQKGFW in-frame - aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6655 JY8QFUQ01B1BZ9 unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*02 F or Homsap IGHV3-33*03 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F or Homsap IGHV3-64*01 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 121 54.48 73/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons gtctggattcaccttcagtagctacggcatgcactgggtccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6656 JY8QFUQ01AH2WA productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6657 JY8QFUQ01C7UO5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVKEDHDSGLRVLLEW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6658 JY8QFUQ01CUO45 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame + tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6659 JY8QFUQ01C7IPL unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 270 68.25 86/126 nt 8 8 X 8.8.X [1.17.7.X] null - No rearrangement found Low V-REGION identity (68,25% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +6660 JY8QFUQ01B2PNO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDVSTRITMRVVVPALDYW in-frame + gtctggattcacgtttagaaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattagtgataatggtgacagcatattccacgcagactccgtgaagggccggttcaccatcaccagagacaactctaagaacatcctgtatctgcacatgaacagcctgagagccgaggactcggccgtatattactgtgcgaaggatgtttccacgcgtattactatgagagttgtggtgccagcccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttcccc +6661 JY8QFUQ01CZEWL unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F (see comment) 506 70.75 150/212 nt 7 8 X 7.8.X [X.17.38.X] null - No rearrangement found Low V-REGION identity (70,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6662 JY8QFUQ01A15SR productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 643 77.78 168/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [X.17.38.11] CVRHVRRFWFDPW in-frame - Low V-REGION identity (77,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggtttcacggttcagtggctctgctatgcactgggtccgccaggcttccgggaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6663 JY8QFUQ01A71E4 No results +6664 JY8QFUQ01ACLKX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1004 95.87 209/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - cctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6665 JY8QFUQ01CK26O productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 738 82.49 179/217 nt 82.03 178/217 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6666 JY8QFUQ01AXQ3V No results +6667 JY8QFUQ01BMRZ4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - tctggagttcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggggctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +6668 JY8QFUQ01BP7WV productive (see comment) Homsap IGHV4-61*05 F, or Homsap IGHV4-61*08 F 870 88.64 195/220 nt 88.18 194/220 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 10 7 13 10.7.13 [1.16.38.11] CARAKDHDDYLVDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 83 in the user submitted sequence), (cause frameshift) tctctggtgcctccatcagcagtagtggtcactactggagttggatccggcagcccccagggaagggactggaattcattggaaaatctattccaatgggaacgccaactacaacccctccttcaagagtcgagtcaccatatcactagacacgtccaaaaaccatttctccctgcagctgacttctgtgaccgccgcggacacggccgtctacttctgtgcgcgagctaaggaccacgatgactacctggtcgacccctggggccaggggatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +6669 JY8QFUQ01DGM3A productive Homsap IGHV4-39*03 F 929 91.36 201/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaact +6670 JY8QFUQ01C1VZ8 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttct +6671 JY8QFUQ01CH9AF productive Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame + Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +6672 JY8QFUQ01AFTGA productive (see comment) Homsap IGHV3-11*01 F (see comment) 724 81.94 177/216 nt 81.48 176/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.16.38.11] CARGYSQKGVFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcagtttcaaggaccactacatgagctggttccgccaggctccagggaaggactggagtgggttgcatacatcgatgccggtgggggtactgactactacgcagactctgtggagggccgattcgtcgtcgccagggaaaatgacaagaatttattgcttctgcaaatgcacagcctgacagtcgaagacacggccgtatattactgtgcgagagggtacagtcaaaaaggggtttttgaccactggggccagggaatcctggtcaccgtttccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggacttcttccccca +6673 JY8QFUQ01AMHM5 No results +6674 JY8QFUQ01DOKXO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6675 JY8QFUQ01AOVMQ productive Homsap IGHV3-9*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + ctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgcgtggaact +6676 JY8QFUQ01AS19K No results +6677 JY8QFUQ01A36CM productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6678 JY8QFUQ01DO6LM productive Homsap IGHV1-2*02 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame + tggatatactttcaccgaccattatgtttactggatgcgacaggcccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +6679 JY8QFUQ01CO3VB No results +6680 JY8QFUQ01DR4J9 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-49*01 F or Homsap IGHV3-49*03 F or Homsap IGHV3-49*04 F or Homsap IGHV3-49*05 F 131 83.78 31/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcgtctttggcgactatgcgatgagctgg +6681 JY8QFUQ01B9M12 No results +6682 JY8QFUQ01AUU0J productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGHW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6683 JY8QFUQ01DSC89 productive Homsap IGHV3-30*07 F, or Homsap IGHV3-30*09 F or Homsap IGHV3-30*12 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*04 F (see comment) 307 75.68 84/111 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 X X 13 X.X.13 [X.X.37.11] CARGGGGKSIPLDNW in-frame - Low V-REGION identity (75,68% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcgtctggcttcacgttcagtagttatggcatctccagagacaattccaagaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatgtaccattgtgcgagaggcggcggtggtaagtccattccacttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6684 JY8QFUQ01C6ILB unknown (see comment) Homsap IGHV4-30-2*04 F, or Homsap IGHV4-34*01 F or Homsap IGHV4-34*02 F or Homsap IGHV4-34*08 F or Homsap IGHV4-34*12 F or Homsap IGHV4-34*13 F or Homsap IGHV4-38-2*01 F or Homsap IGHV4-38-2*02 F or Homsap IGHV4-39*01 F or Homsap IGHV4-39*05 F or Homsap IGHV4-59*04 F or Homsap IGHV4-59*05 F or Homsap IGHV4-59*08 F 414 91.0 91/100 nt X X X X.X.X [X.X.33.X] null + No rearrangement found stop codons tctatggagtcgagtcaccatatgagtagacacctccaagaaccagttctccctgaaggtgagctctgtgatcgccgcagacacggctgtgtattactgtgcgagacgtaagggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6685 JY8QFUQ01CY3QB No results +6686 JY8QFUQ01C49AP No results +6687 JY8QFUQ01COADP No results +6688 JY8QFUQ01BINUU unproductive (see comment) Homsap IGHV3-7*01 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 181 87.23 41/47 nt Homsap IGHD4-17*01 F 2 8 8 X 8.8.X [1.17.38.11] CSRLP*G#W out-of-frame + stop codons tctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactcccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc +6689 JY8QFUQ01C0O0F No results +6690 JY8QFUQ01BJS1R productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 962 92.41 207/224 nt 91.96 206/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 7 7 8 7.7.8 [5.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) ccgtctgcagcctctggattcattgtcaatagcactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6691 JY8QFUQ01A3I5W productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6692 JY8QFUQ01CT3DH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6693 JY8QFUQ01C1AGN productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggGcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6694 JY8QFUQ01CUKBL productive Homsap IGHV4-61*02 F 830 86.43 191/221 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-21*01 F 2 10 7 19 10.7.19 [1.17.38.11] CAREAPKTAGDSYGSLAMDVW in-frame - tctctggtggctccgtcagtagtggttcttactactggagctggacccggcagcccgccgggaagggactggagtggattgggcgtgtccacagcggtggcagttccgactacaacccgtccctcacgggtcgagccaccatcttagtggactcctccaagaatcagttctccctgaggctgacctctgtgacggccgcagacgcggccgagtatttctgtgcgagagaggcgcccaagacagcaggtgattcctacggctctctcgctatggacgtctggggccaagggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6695 JY8QFUQ01BKB7Y productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6696 JY8QFUQ01CACJX unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 416 75.68 112/148 nt 8 7 X 8.7.X [1.17.16.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CACJX ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (75,68% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgtatcactactagtggtaccacattctacacggactacttccccgaaccggtgacggtgtcgtggaactca +6697 JY8QFUQ01DC3ZI productive (see comment) Homsap IGHV3-7*01 F 973 94.06 206/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [2.17.38.11] CSRLLEEW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'A' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); gcctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggaAgtgggtggccaatatCaaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6698 JY8QFUQ01BROZ6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARFGPLTRPDYWG in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggcccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6699 JY8QFUQ01CXBH4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgAaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtggggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6700 JY8QFUQ01AXX5G unproductive (see comment) Homsap IGHV4-61*01 F 942 92.27 203/220 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD6-6*01 F 2 10 7 X 10.7.X [1.17.38.11] CTRGAVHL*QPV# out-of-frame + stop codons ctctggtggctccatcagcggtagtactaactactggagctggattcggcagcccccagggaagggactggaattcattgggtatatctattccagtgggaggaccaactacaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccagttctccctgaggctggcgtctgtgaccgctgcggacacggccgtgtattactgtacgaggggggcagtacacttatgacagcccgtggggacaggggacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6701 JY8QFUQ01B6IMA unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 700 91.02 152/167 nt 8 7 X 8.7.X [1.17.22.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01B6IMA ; 8 AA in Homsap_IGHV3-11*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatct +6702 JY8QFUQ01DLDLD productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1002 96.73 207/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFYYW in-frame + tggatacaccttcaccagctactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagacttttactactggggccagggaaccctggtcaccgtcccctcagcatcccctgaccagcccctaaggtcttcccgctgacgcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +6703 JY8QFUQ01C052J No results +6704 JY8QFUQ01CFH6C productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + ctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +6705 JY8QFUQ01CMR70 No results +6706 JY8QFUQ01CTNJK unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 97 52.14 73/140 nt 10 9 X 10.9.X [1.17.9.X] null - No rearrangement found stop codons tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6707 JY8QFUQ01AQGGA No results +6708 JY8QFUQ01AQY9A productive Homsap IGHV3-9*01 F 968 93.58 204/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDAMGGAGDWAAFGIW in-frame - cctctggcttcatctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagcgctaccatagaatatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctggaaatcaacagtctgagacctgaagacacggccttatactactgcgcaaaagatgcgatgggaggagctggtgattgggctgcttttggtatctggggccaggggacaatggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6709 JY8QFUQ01B9JFJ No results +6710 JY8QFUQ01A5GYE No results +6711 JY8QFUQ01CVDG8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKSITMVRGLI#YHFDYW out-of-frame - ctctggattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcgcaactattatttatagtggcgatagtacatactacgcagattccgtgaggggccggttcaccatctccagagacaattccaagaacactctgcatctgcatatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaagtatcactatggttcggggacttattattaccacttcgactactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +6712 JY8QFUQ01B3WC4 No results +6713 JY8QFUQ01AF0ED No results +6714 JY8QFUQ01DIFDC No results +6715 JY8QFUQ01B9NVT No results +6716 JY8QFUQ01CCU8Z productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); cagcctctggattctccgtcagtaattactggatgcactgggtccgccaggctccagggaaggggctggtgtgggtctcacgtgttaatggtgatAgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6717 JY8QFUQ01BM5JT No results +6718 JY8QFUQ01C021D productive Homsap IGHV3-7*01 F 1041 97.27 214/220 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [2.17.38.11] CVSSPYFYDSNGYW in-frame - ggcctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6719 JY8QFUQ01A1KW0 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 412 88.46 92/104 nt 87.5 91/104 nt 8 8 X 8.8.X [1.16.1.X] null - No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 47 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggagggggctggagtgggtctcagccattagtggcagtggtagtcggacatatt +6720 JY8QFUQ01C6766 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6721 JY8QFUQ01CV2GG productive Homsap IGHV1-8*01 F 840 87.85 188/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARVGGTHYHYGVDVW in-frame + cggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagatctgacgacacggccgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6722 JY8QFUQ01DGX17 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CGKPIVGATGREMPVSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagcaactatgccatgaactgggtccgccaggttccaggggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccc +6723 JY8QFUQ01CK5JU No results +6724 JY8QFUQ01BM9IX unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 87.56 190/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-21*02 F 2 8 8 X 8.8.X [1.17.38.11] CAKEASPSGG*##HFDHW out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcacctttagcagctatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtcgcacttattagcgatagggctgataaaacagcgtacgcagggtccgtgaagggccgattcaccatctctagagacaattccaagaatatattatatcttcaaatgaacagcctgagagccgacgacacggccgtatattattgcgcgaaagaagcctccccctcgggggggtgacgaccactttgaccactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6725 JY8QFUQ01A6WE1 unknown (see comment) Homsap IGHV3-7*01 F 1026 96.77 210/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6726 JY8QFUQ01AE1O5 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6727 JY8QFUQ01DQQ34 No results +6728 JY8QFUQ01A0NXG No results +6729 JY8QFUQ01BE1FW unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +6730 JY8QFUQ01CFT4U No results +6731 JY8QFUQ01CMP8A No results +6732 JY8QFUQ01AE0CK unproductive Homsap IGHV4-4*07 F (see comment) 688 80.09 173/216 nt 79.63 172/216 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-9*01 F 1 8 7 X 8.7.X [2.17.38.11] CARESTNSIGDPRHLD#L out-of-frame - Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'CAANACGAC' (9 nucleotides at position 19 to 27 in the user submitted sequence), (do not cause frameshift); gtctctggtggccccatcCAANACGACatggacttctattggacgtggatccggcagtccgccgggaggggactggagtggctcggacgtgtctatatgaatggcattagtgaccacaatccagtcttcactagtcgtctcaccatgtccattgacacgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcggactcggccctatattactgtgcgagagaaagtactaattcgattggcgacccgagacaccttgactcttgggccagggaaggttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6733 JY8QFUQ01CC1QB unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 719 85.28 168/197 nt 84.77 167/197 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) tctgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6734 JY8QFUQ01DHA3U productive Homsap IGHV3-48*03 F 802 85.39 187/219 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [2.17.38.11] CVRQTGDYYFFGLDVW in-frame - gcctctggattcgccttcaaaagttttaacatgaattgggtccgccaggcttcagggaaggggccggagtggattgcatacattaatggaagagggactaacatctactatgcagactctgtgaagggccggttcaccatctccagagacaacgcccagaacgcagtgcatctgcagatggaccgcctgagagtcgaggacacggccctatattactgtgtgagacaaactggagactactatttcttcggtctggacgtctggggccaaggaaccacggtcaccgtctcttcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6735 JY8QFUQ01C85QL productive Homsap IGHV3-7*01 F (see comment) 733 82.41 178/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6736 JY8QFUQ01A3VFN No results +6737 JY8QFUQ01CAXY5 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1031 97.25 212/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEFGEGPDWELLP#YFHYW out-of-frame + cctctggattcacgttcagtggctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtatcatatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctctctctgcaaatgaacagcctgagagctgaggacacggctgtatattactgtgcgaaagaatttggggagggccctgactgggaactactaccagtactttcactattggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctccgacagcaccccccaagatgggaacgtggtccgtngcatgcctggtccagggcttcttccccca +6738 JY8QFUQ01A0X3X productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F (see comment) 804 84.75 189/223 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD3-10*01 F 3 8 10 16 8.10.16 [1.17.38.11] CARIWEPSITFLHTFDVW in-frame + Low V-REGION identity (84,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttcggggttcacctttggtgactatgctatcagttggttccgccaggctcctgggaaggggctggagtggattgctctccttaggagcaaaccttataattcaccaacacaattcgccacgtctgtgaaaggccgattcactgtctcaagagatgactcggaaagtgtcgcctatctgcacatgaacagcctgcaaaccggggacacagccgtgtattattgtgccagaatatgggaaccaagtattactttccttcatacatttgatgtctggggccgagggacacgggtcaccgtttcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6739 JY8QFUQ01CTKV2 unknown (see comment) Homsap IGHV3-7*02 F 100 57.83 48/83 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found ctctggattcgcctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6740 JY8QFUQ01CXIGS productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F 815 86.24 188/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARPHHNSGYSFDHW in-frame + cgtctgatttcaacgtcggtgactttgacatgcactgggtccgccagactccagacaaggggctggagtgggtggcacttttttggtatgacggaaagaggaaatattatgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacaccctgtatctgcaaatggacagcctgagagccgacgacacggctacctacttttgtgcgaggcctcatcataatagtggttattcctttgaccactggggccagggaacccaggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6741 JY8QFUQ01CRE9K No results +6742 JY8QFUQ01AJBT6 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1040 97.71 213/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame - cgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6743 JY8QFUQ01CFIT0 productive (see comment) Homsap IGHV3-11*01 F (see comment) 693 80.18 174/217 nt 79.26 172/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-25*01 F 2 8 8 11 8.8.11 [1.17.37.11] CVRDRSRGIADPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 169 in the user submitted sequence), (cause frameshift) cgtctggattcaccttcactgactattggatgagttgggtgcgcctgaccccaGgggaagggtctagaatgggtttcgttcataagtggaagtggcaatagtgtctggtatgcagactctgtgaagggccgattcattatctccagagacaacgccaaaaatttagtcttttggacatgaacagcctgagagtcgaggactcggccatgtattattgtgtgagagaccgcagcaggggaatagcagatccttggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcatcgcctgcctggtccagggcttcttcccc +6744 JY8QFUQ01C1HPT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - tctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6745 JY8QFUQ01AQFXP No results +6746 JY8QFUQ01A1WEO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKSRLGRDTGWPP#ENW out-of-frame - cctctggattcaccgtgaatagttgtgccatgagctgggtccgccaggttccagggaaggggccggaatgggtctcaactcttggtatcagggacgatagtgcatactacacagactccgtgaagggccggttcaccatctccagggacaaatccaagaacactctgtctctgcaaatgaacagcctgagagtcgaggacacggccctatattactgtgcgaaatcccgtttggggcgtgacactggctggccccccttgaaaactggggcccgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6747 JY8QFUQ01AMLYW No results +6748 JY8QFUQ01DE0U1 No results +6749 JY8QFUQ01CT2N6 No results +6750 JY8QFUQ01DNY7K productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.24 202/219 nt 91.32 200/219 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [2.17.38.11] CVKRLEAVADDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'A' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); gcctctggattcacgtttagcagctatgccatAgggctgggtccgccaggctccagggaAaggggctggagtgggtctcaactattagtggcagtggtcggagcgcatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaatacgatgtctgtacaaatgagcggcctgagagccgacgacacggccatatattactgcgtgaaaaggttggaagcagtggctgatgatgcctttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6751 JY8QFUQ01CT6MZ productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactca +6752 JY8QFUQ01BW86R No results +6753 JY8QFUQ01ACO2Q No results +6754 JY8QFUQ01AR84C productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctgggtcaagggactacttccccgaaccggtgacggtgtcgtggaactca +6755 JY8QFUQ01BX7TJ unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt 8 7 X 8.7.X [4.17.38.11] CARGDPIFMI (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggaccccattttcatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6756 JY8QFUQ01BYRXT productive Homsap IGHV3-21*04 F (see comment) 662 78.44 171/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVRLFTSDGVRGDYW in-frame - Low V-REGION identity (78,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctccggtttcatcttcagtcacttcagcatgaactgggtccgccaggctccaggaaagggcctggagtggatcgccgacatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcgacgatacggccacctattattgtgtgaggctcttcaccagcgatggagtgagaggcgactactggggccagggcgcccgggttctcgtctccgcagcttccaccaagggcccatcggtcttccccctggcgccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6757 JY8QFUQ01B0M96 No results +6758 JY8QFUQ01AI6PH No results +6759 JY8QFUQ01BO7P5 productive (see comment) Homsap IGHV4-61*02 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD3-3*01 F 3 9 7 16 9.7.16 [1.17.38.11] CARERSASIGGAGEIDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 37 of V-REGION: 3 nucleotides (from position 30 in the user submitted sequence), (do not cause frameshift) tctctggcggccccatcagtggtggtggttactggagttggatccggcagcccgccgggaagggactggagtggatcggacatatttataatagtgggaacatcaactacagtccctccctcaagagtcgggttttcatgtcagtagacacctctaagaagcagttttccctgaggttgaactctgtgaccgccgcggacacggccgtgtattattgtgcgagagaacgtagtgcttcgattggcggagcgggagagattgactcctggggccagggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6760 JY8QFUQ01DBCBZ productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F (see comment) 768 82.96 185/223 nt 82.51 184/223 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 10 13 8.10.13 [1.17.38.11] CSTSGPNGYHSTYPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); ctctggattcgccttcaatatcaagtggatgagttgggtccgccaggctccggggaaggggcttgagtgggtcggccgcatcaagagcagcgctgatggtgcgacaacagacaccattgagcgcgtgagagacagattcaccatctcaagagatgactcaaaaaaGtacactgtacttgcacatgaccagcctgagaaccgaggacacaggcatgtattattgttccacaagcgggccaaatggatatcactccacatatccctggggcccggggacccaggtcaccgtctcctcagcatccccgactagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +6761 JY8QFUQ01BW5FT productive Homsap IGHV3-48*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDRGGSAYPIFDYW in-frame + ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcttccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6762 JY8QFUQ01C9K16 No results +6763 JY8QFUQ01BLLS0 unknown (see comment) Homsap IGHV3-23*02 F, or Homsap IGHV3-23*03 F or Homsap IGHV3-30*05 F 147 53.23 99/186 nt 8 7 X 8.7.X [1.17.28.X] null + No rearrangement found ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6764 JY8QFUQ01CAGEH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6765 JY8QFUQ01BBXN0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame + ctctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccc +6766 JY8QFUQ01C3WX5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6767 JY8QFUQ01AHBEO productive (see comment) Homsap IGHV3-72*01 F 971 92.86 208/224 nt 92.41 207/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); cctctggattcaccttaagtgatcactacatggactgggtccgccaggctccaAgggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6768 JY8QFUQ01DV4HU productive (see comment) Homsap IGHV3-7*01 F 882 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 92 of V-REGION: 'N' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift); ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgNaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggccagtcggtcttccccctgcgccctnctccaggagcacctccgagagcacagcggccctggctgccctggtcaaggatacttccccgaaccggtgacggtgtcgtggaactca +6769 JY8QFUQ01BAU1U productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 75 of V-REGION: 'C' (1 nucleotides at position 130 to 130 in the user submitted sequence), (cause frameshift); ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgGggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccCgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgctggtccaggggcttcttccccca +6770 JY8QFUQ01CVWWZ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6771 JY8QFUQ01A0BVQ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt 94.01 204/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 7 8 X 7.8.X [1.17.38.11] CAKKNIIIRGLI#YNFDYW out-of-frame - Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift) cctctggattcacctttagcaactttgcatgacctgggtccgccaggctccagggagggggActggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaaacattataattcggggacttatttatacaactttgactactggggccgcggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc +6772 JY8QFUQ01BIOHN No results +6773 JY8QFUQ01B9RXS unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 654 77.27 170/220 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (77,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release agcctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6774 JY8QFUQ01CKP7P productive (see comment) Homsap IGHV3-7*01 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.37.11] CSRLLEEW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +6775 JY8QFUQ01BZ4W8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt 83.94 183/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); gtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctngggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6776 JY8QFUQ01DIVTR productive Homsap IGHV1-3*01 F (see comment) 351 73.53 100/136 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 X 7 14 X.7.14 [X.X.38.11] CARGRYDSSGRGHEYW in-frame - Low V-REGION identity (73,53% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcaccagtttcagtatccattggaagttccaggacagactcaccattactagagacacatccgcgagcacagcctacatggacctgagcagcctgagatctgaagacacggctgtctattactgtgcgagagggcgctatgatagtagtggtcgtggccatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6777 JY8QFUQ01CTMOR No results +6778 JY8QFUQ01BNH4P productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 807 85.45 188/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + ctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6779 JY8QFUQ01CKBIE productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctaaatttgacttcagtgactatggcatgaactgggtccgccaggttccagggaaggggctggagtgggtctcctacataagtcgtctgagtcgccaaatatatgtcgctgacccagtgaagggccgattcaacatctccagagacaacgccaagaattcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6780 JY8QFUQ01DNQI8 unproductive Homsap IGHV4-61*02 F 843 87.27 192/220 nt 86.82 191/220 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD3-3*01 F 3 10 7 X 10.7.X [1.17.38.11] CARDDLEWSKQKYSFYGVDV# out-of-frame - in CDR1-IMGT at codon 34 of V-REGION: 'T' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); ctctggtggctccatcaccTagtggtacttacttctggacctggatccggcagcccaccgggaagggactcgaatggattgggcgtatccacgccaatgggaacaacgtggtcaacccctccctcaggagtcgggtcaccgtgtcagtagacacgtccaggaaccaattctccctgaggctgagttctgtgaccgccgcggacacggccgtctattactgtgcgagagatgatttggagtggtccaaacaaaaatactccttttacggtgtggacgtctgggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctaagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6781 JY8QFUQ01CD8PO productive (see comment) Homsap IGHV2-5*02 F 1165 97.94 238/243 nt 97.53 237/243 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 2 10 7 11 10.7.11 [9.16.38.11] CAHRRIRFGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) gaccctcacgctgacctgcaccttctctgggttctcactcagcactggtggagtgggtgtgggctggatccgtcagccccaggaaaggccctggagtggcttgcactcatttattgggatgatgataagcgctacagcccatctctgaagagcagactcaccatcaccaaggacacgtccaagaaccaggtggtcctcacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacaggaggatacgattcggctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggctcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6782 JY8QFUQ01CADHA No results +6783 JY8QFUQ01CODZI No results +6784 JY8QFUQ01AFF4Y unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSEFLLDG#YW out-of-frame - ctctggattcagctttagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaaatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtttttgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgattagtagtgagtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6785 JY8QFUQ01DA7FV No results +6786 JY8QFUQ01CLF5G No results +6787 JY8QFUQ01AXW2R unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 95 82.14 23/28 nt 7 X X 7.X.X [2.X.X.X] null + No rearrangement found tctccgggggacagtgtctctagcaaca +6788 JY8QFUQ01B5YQQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [1.17.38.11] CVRYDYSRLHRSNYFGPW in-frame - tctctggattcaccttcatcagttatggcatgagttgggtccgccagtttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6789 JY8QFUQ01BSFQQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 751 83.33 180/216 nt 82.41 178/216 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD1-26*01 F 2 8 8 17 8.8.17 [1.17.38.11] CVRVPTQWFPPFHTHFDIW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); tctggattcaccttTtagctcttttaccatgagctGgggtccgccagactccggggaagggcctggaatgggtctctgctatcagtggcagcgatgatcgcacatcttatgttgactccgtgaagggccgcttcaccatctccagagacacttccaggaatacactgtttctgcagatgaacagcctgagcgccgaagatacggccacatacttttgtgtgagagtccccactcagtggtttccacccttccacactcactttgacatctggggccagggaaccgtggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6790 JY8QFUQ01CE58M productive Homsap IGHV1-2*02 F 831 87.85 188/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [0.17.38.11] CARDGISMTLVRGVRPFDYW in-frame - tggatacaccttcatcggccattatatacattgggtgcgacaggcccctggacaagggcttgaatgggtggggtggatcaaccctaacagtggtgttacaaactatgcacagcagtttcaggacagggtcaccatgaccgtcgacacgtccatcagcactgcctacatggacctcaaaagtctaaagtctgacgacacggccatctattactgtgcgagagacggaataagtatgactctggttcggggagttaggcccttcgactactggggccagggaaccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6791 JY8QFUQ01C2NMH unproductive Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 97.69 211/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [1.16.38.11] CASRLRSSRW#YW out-of-frame - in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 76 of V-REGION: 'G' (1 nucleotides at position 132 to 132 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagctatagcatgaactgggtccgccagctccagggaagggctggagtgggtttcatGacattagtGagtagtagtagtaccatatactacgcagactctgtgaagggccgaGttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttcccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6792 JY8QFUQ01BC26X productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +6793 JY8QFUQ01BDS3U unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt 86.64 188/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEEGCYWSLL##DHW out-of-frame + stop codons in FR2-IMGT at codon 46 of V-REGION: 'TC' (2 nucleotides at position 50 to 51 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'CG' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccacctccgccatggcctgggtccgccagggtTCccagggaaCGgggcgtggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggctgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6794 JY8QFUQ01COHJN No results +6795 JY8QFUQ01ABSUS productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 922 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); tctggaattcagcttcagtacctataacatgaactgggtccgccaggctcCcagggaaggggctggantgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6796 JY8QFUQ01DLQUC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtgGgtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6797 JY8QFUQ01DMH7A No results +6798 JY8QFUQ01AKG6U productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 867 89.72 192/214 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKESLVRGVISYYFNDW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcaccgtcagtaacaactacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggtgacacatactacgcagactccgtgaagggccgattcaccatctccagagacaacgccaagaatacactttttcttcaaatgacttccctgagagtcgaagatacggccatttattactgtgcgaaagagtctctggttcggggagtcatctcatactactttaatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6799 JY8QFUQ01AEPA7 No results +6800 JY8QFUQ01B1PJB unproductive Homsap IGHV3-72*01 F 1073 98.64 218/221 nt 98.19 217/221 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.16.38.11] CLRPPRYD#PG out-of-frame + in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) tctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6801 JY8QFUQ01BCE7T unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F or Homsap IGHV1-69*01 F or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F 86 57.53 42/73 nt 56.16 41/73 nt X X X X.X.X [24.X.X.X] null + No rearrangement found in FR1-IMGT, from codon 7 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgctctcggaggtgctcctggagcagggcgccagggggaagaccgatgggcccttggtggaggtgacgaagccaccagaga +6802 JY8QFUQ01BKYGD productive Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 735 81.74 179/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARVWVAGSRDENFDSW in-frame + Low V-REGION identity (81,74% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcgggtggttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgacctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6803 JY8QFUQ01CWFXN unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt 87.1 189/217 nt Homsap IGHJ1*01 F 107 67.31 35/52 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CLRPPRYDPW# out-of-frame - in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctgggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6804 JY8QFUQ01AD84I productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 947 92.31 204/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARQSFDFAWQWQVDYYFEYW in-frame + tctctggtggctccgtcagcagtagcacttactactggggctggctccgccagtccccagggaaggctctggagtggattgggactatccatcatagtgggagcacctaccagaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaggaaccagttctccctgaggctgagctctgtgaccgccgcagacacggctctttattactgtgcgagacaaagctttgatttcgcgtggcagtggcaggtagattattactttgaatactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcatcgcctgctggtccagggcttcttcc +6805 JY8QFUQ01A7STL productive (see comment) Homsap IGHV4-59*02 F 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARMPPGGVHFDHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'GC' (2 nucleotides at position 45 to 46 in the user submitted sequence), (cause frameshift); tctccggtgcctccgtgagtagtgactactggagctgggtccggGCagtcccccaggaaaggggctggagtggattggatatatctattccactgggagcaccaactacaacccctccctcaagagtcgactcaccatgtcactggacacgcccaagaacgagttctccctgaaactgagctctgtgacagctgcggacacggccgtctatttttgtgcgagaatgcccccgggaggtgtccactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6806 JY8QFUQ01AQ96Q No results +6807 JY8QFUQ01A9BDW No results +6808 JY8QFUQ01DVVUT No results +6809 JY8QFUQ01CWF86 unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F 111 58.62 51/87 nt 57.47 50/87 nt 5 X X 5.X.X [24.X.X.X] null + No rearrangement found in FR1-IMGT, from codon 7 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgctctcggaggtgctcctggagcagggcgccagggggaagaccgatgggcccttggtggaggttcttcttatgattattcaaggtgaatccaga +6810 JY8QFUQ01C1MUW productive Homsap IGHV3-7*01 F 1002 96.73 207/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [0.17.38.11] CATSPFTVTTGKDAYW in-frame - tggattcaccttcaggagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgacaaattctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6811 JY8QFUQ01C5YDT unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANYW# out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6812 JY8QFUQ01A2MA0 No results +6813 JY8QFUQ01BFQYE productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKLTYYDVGDYW in-frame + ctctggattcacctttgatgatcatgccatgcactgggtccggcaagctccagggaagggcctagagtgggtcgcgggtattacttggaatagtggtcacatagtctatgcggactctgtgaagggccgattcaccatctccagagacaacacgaagaactccctctatctgcagatgaacagtctgaccgctaaagacacggccttatattactgtgccaaactcacatattacgatgttggtgattattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +6814 JY8QFUQ01ACUDH unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F 617 88.96 137/154 nt 8 8 X 8.8.X [1.17.17.X] null - No rearrangement found tctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcatacattagtgggagtgcgactaccatatcctacgcagactttgcgaagggccgattcaccatctccagggcttcttccc +6815 JY8QFUQ01CE2ZP No results +6816 JY8QFUQ01DFNQ1 productive (see comment) Homsap IGHV3-23*05 F 799 86.38 184/213 nt 85.45 182/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 7 7 9 7.7.9 [1.17.38.11] CTREVGATDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggatcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6817 JY8QFUQ01B7H4M No results +6818 JY8QFUQ01AKKUR productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 909 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); tccggaattcagtttcagtacttataacatgaattTgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6819 JY8QFUQ01C1731 productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 91 to 96 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagttTtctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +6820 JY8QFUQ01AB1YG No results +6821 JY8QFUQ01B5191 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 353 86.17 81/94 nt 8 5 X 8.5.X [1.17.X.X] null - No rearrangement found ctctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc +6822 JY8QFUQ01ARJZM No results +6823 JY8QFUQ01C3WEI productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaAaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +6824 JY8QFUQ01ARC0B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6825 JY8QFUQ01AWT03 productive (see comment) Homsap IGHV3-7*01 F 752 93.06 161/173 nt 92.49 160/173 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.23.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 71 of V-REGION: 45 nucleotides (from position 120 in the user submitted sequence), (do not cause frameshift) cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6826 JY8QFUQ01BSDSX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 994 95.83 207/216 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6827 JY8QFUQ01CH3N8 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDNYGDYW# out-of-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6828 JY8QFUQ01AJLRE No results +6829 JY8QFUQ01A346T productive Homsap IGHV3-66*02 F 889 91.08 194/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + tctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctaaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6830 JY8QFUQ01BSUVD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - gtctggattcacctccagtacctatggtatgctctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctccttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6831 JY8QFUQ01C3KRL No results +6832 JY8QFUQ01DEI0V productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 925 90.99 202/222 nt 90.09 200/222 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [2.17.38.11] CARGGSGGSYWNLIRDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); gtctctgatgactccgtcagcagtggtcgCttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattAgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6833 JY8QFUQ01DINBU unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found ctctggattcatcttcagtagctactggatgcactggg +6834 JY8QFUQ01CT2XT unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1029 98.13 210/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [0.17.38.11] CARGPPGGGSYYA#FDYW out-of-frame + tggatacaccttcaccagctactatatgcactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcaaccctagtggtggtaccacaaactacgcacagaagttccagggcagagtcaccatgactagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaggactcggccgtgtattactgtgcgagaggaccccccggtggcgggagctactacgccattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttct +6835 JY8QFUQ01DFC7X No results +6836 JY8QFUQ01CO2F0 productive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 920 90.95 201/221 nt 90.5 200/221 nt Homsap IGHJ4*02 F (see comment) 231 97.92 47/48 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARDRLGSCSGASCPVYYFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtgattcctcctggacctggatccgccagtacccagggaagggcctggagtggattgggtacatctctggcagtgggggActcctactccaacccggccctcaagagtcgagttaccatatcagtggacacgtctaagagccagttcttcctggaactgagttctgtgactgccgcggacacggccgtctattactgtgcgagagatcggctgggatcttgtagtggggctagctgccccgtctactactttgactcctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccg +6837 JY8QFUQ01BPLO0 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 94.17 210/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaaGtatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6838 JY8QFUQ01BUQ4R unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6839 JY8QFUQ01C8QAM No results +6840 JY8QFUQ01CHAWC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 775 84.02 184/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6841 JY8QFUQ01AYC69 No results +6842 JY8QFUQ01AS54C productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame - cctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6843 JY8QFUQ01CKEU6 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 936 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggcgtggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6844 JY8QFUQ01BY164 unproductive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 281 81.4 70/86 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-13*01 F 3 X X X X.X.X [X.X.28.11] CVKDRKGSNWYYFEN# out-of-frame + Low V-REGION identity (81,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactgggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6845 JY8QFUQ01BFOI5 No results +6846 JY8QFUQ01DL6Z6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 995 95.41 208/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctacaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6847 JY8QFUQ01BJLUL No results +6848 JY8QFUQ01C589C unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +6849 JY8QFUQ01BCNLI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactca +6850 JY8QFUQ01CRCG6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame + ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6851 JY8QFUQ01CC3QM unproductive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-8*02 F 1 8 8 X 8.8.X [0.17.38.11] CARDGYLPGNG#DFW out-of-frame + tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacgggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6852 JY8QFUQ01BEVA6 productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 614 96.95 127/131 nt 96.18 126/131 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 X 9 8.X.9 [1.3.31.11] CTREVGATDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 39 in the user submitted sequence), (do not cause frameshift) cgtctggattcaccttcaggagctattggatgagctggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6853 JY8QFUQ01C2LOK productive Homsap IGHV3-7*01 F 922 91.71 199/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame - ctctggattcacctttagtaactattacatgagttgggtccgccaggcnccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6854 JY8QFUQ01AQEFQ No results +6855 JY8QFUQ01A7SLH productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.37.11] CARDSRHSASGSYSDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 176 in the user submitted sequence), (cause frameshift) gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6856 JY8QFUQ01AIXP3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 846 88.02 191/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDWSGYARYDAMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcggtgcctacggcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcattcgttaatagtgtaagtagtcacatatattacgcagactcagtgaggggccgattcaccatctccagagacaacggcgagaactccgtttatctgcaaatgtacagcctgagagccgaagacacggctacatactactgtgtgagagatagtgactggtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6857 JY8QFUQ01AYSB5 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 7 13 8.7.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 65 of V-REGION: 2 nucleotides (from position 103 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6858 JY8QFUQ01C8D0M productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 796 85.65 185/216 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6859 JY8QFUQ01CUQW4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6860 JY8QFUQ01DAAIL productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6861 JY8QFUQ01A3IMB productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 175 75.81 47/62 nt Homsap IGHD3-16*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARAVGQRGYDGTDLW in-frame + ctctggattcatgttcagcagttattggatgagctgggtccgccaggatccagggaaggggctggagtgggtggccaatataaacgaagaaggaagtgagaaatattatgtggactctgggaagggccgattcaggatctccagagacaacgccaagaattccgtgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgcgagagcagtggggcagcgaggctacgacggtacagacctctggggccaagggaccacggtcatcgtctccacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6862 JY8QFUQ01CVI9D productive Homsap IGHV3-74*03 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6863 JY8QFUQ01C95KI productive Homsap IGHV1-2*02 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame + tggatatactttcaccgaccattatgtttactggatgcgacaggcccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtatattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6864 JY8QFUQ01DCDOK No results +6865 JY8QFUQ01BGOI8 productive Homsap IGHV3-64*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + cctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6866 JY8QFUQ01CIG2U No results +6867 JY8QFUQ01CS4IY No results +6868 JY8QFUQ01BH3Y1 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 853 89.2 190/213 nt 87.79 187/213 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.37.11] CASGGYSGSGEYFLRW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 66 of V-REGION: 'G' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 77 of V-REGION: 1 nucleotides (from position 131 in the user submitted sequence), (cause frameshift) ctctgacttaagcgtcagtgacaattacGatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatGactacgcagagtccgtgaagggccgattcgcgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6869 JY8QFUQ01CF60W productive Homsap IGHV4-61*02 F 884 89.14 197/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.38.11] CARDFGGSYNLVAYW in-frame + tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6870 JY8QFUQ01BXDWI productive (see comment) Homsap IGHV3-7*01 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); tctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6871 JY8QFUQ01AVPMG productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 956 92.76 205/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARRGSYGSGSYYPW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggcgccatcagcagtaatagttactactgggactggatccgccagcccccagggaaggggctggagtggattgggagtatgttttatactggggtcaccttctacaacccgtccctcaagagtcgagttaacatttccgtggacacgtccaagagccagttctccctgaggctgagctctgtgaccgccgcagacacggctgtgtatcactgtgcgagacgtggttcctatggttcggggagttattatccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +6872 JY8QFUQ01DSPRR unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDY## out-of-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggcccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6873 JY8QFUQ01BQ91P productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6874 JY8QFUQ01AXDDD No results +6875 JY8QFUQ01DIZ9U productive (see comment) Homsap IGHV3-7*01 F 821 85.59 190/222 nt 85.14 189/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [3.17.38.11] CAREQSSRGYPLDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); ctccggaatttccaatttttgggngacttttggttgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAagcaagatggaagtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaggaactcactgtttctgcaaatgaacagcctgagaggcgacgacacggctgtctattactgtgcgagagaacaatcctcgaggggatatccacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6876 JY8QFUQ01CPWP1 No results +6877 JY8QFUQ01AV8GT productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 795 84.3 188/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 10 15 8.10.15 [1.17.38.11] CTTDSFHIAVHGVFDFW in-frame + Low V-REGION identity (84,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttctgcattcatgttcaacaaagcctggatgaattgggtccgccaggctccaggaaagggactggagtgggttggccgtattaaaagtaacggcgacggtgcgacagtcgactacgctgcacccgtgaaaggccgattcaccatctcaagagatgattcacagaataccctcttcttacaaatgagcagcctgaaagccgaggacacagccgtctattattgtaccacagatagcttccatattgcagtgcatggcgtctttgacttctggggccagggagccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccaggctcttccccca +6878 JY8QFUQ01B21O0 productive (see comment) Homsap IGHV3-7*01 F 1022 96.79 211/218 nt 96.33 210/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGcctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6879 JY8QFUQ01DQRNC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 996 95.0 209/220 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARGPRSRGYGMDVW in-frame + aacctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaact +6880 JY8QFUQ01AG024 productive (see comment) Homsap IGHV3-7*01 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 6 8.8.6 [1.17.37.11] CVKSIDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ctctggattcacttttagcagtttttggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagtgggatggaagtgataaaagtatatggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactatatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtgaaaagcattgactcctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcccagggcttcttccccca +6881 JY8QFUQ01AB5UK No results +6882 JY8QFUQ01AVBOK unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 308 61.39 124/202 nt 8 8 X 8.8.X [1.17.32.X] null - No rearrangement found Low V-REGION identity (61,39% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6883 JY8QFUQ01CN8F8 No results +6884 JY8QFUQ01AOUA3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6885 JY8QFUQ01AW2LQ productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +6886 JY8QFUQ01AN2J8 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAKDFYYGCDYW in-frame + tctctggattcaacttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagtcattgcatacaatggaggaaatatatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaaggataccctgtacttgcacatgaccagtctgagacctgatgacacggccatgtattactgtgcgaaagacttttattatggttgcgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagccacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +6887 JY8QFUQ01CK8OV No results +6888 JY8QFUQ01ASU8O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6889 JY8QFUQ01CT3CN productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.37.11] CVSDLAGQKGFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 167 in the user submitted sequence), (cause frameshift) tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6890 JY8QFUQ01C6S8S No results +6891 JY8QFUQ01CH9SI unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CAREVKYGDDTG#WFDPW out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); tctggattccccatcagtgGgctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaagggccgattcaccatctccagagacaattccaagaacaccctgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattactgtgcgagagaggtgaaatacggtgacgacacggggggtggttcgacccctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6892 JY8QFUQ01BANC8 No results +6893 JY8QFUQ01DUVAT unproductive Homsap IGHV4-39*03 F 930 90.99 202/222 nt 90.09 200/222 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD2-8*01 F 2 10 7 X 10.7.X [2.17.38.11] CTREGPYYYGMDV## out-of-frame - in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 75 of V-REGION: 'C' (1 nucleotides at position 136 to 136 in the user submitted sequence), (cause frameshift); tgtctctggtgactccatcagtaatactgattactactgggtctggatccgccagaccccagggaagggactggagtggattgggagtatcgatttcagtgggagcacctactacaacccgtGccctcaagagtcCgagtcaccatatccatagacacgtccgagaaccggttctccctgaggttgacctctatgaccgccgcagacacggccgtctattactgtacgagagagggaccctactactacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6894 JY8QFUQ01A5PWS productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 975 95.33 204/214 nt 94.86 203/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD1-26*01 F 1 7 7 18 7.7.18 [1.17.38.11] CARGWAQQAGATFVGWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 27 in the user submitted sequence), (cause frameshift) tctatggtgggtccttcagtggttacactggaactggatccgccagcccccagggaaggggctggagtggattggggaaatcaatcatagtggcaggaccaactacaacccgtccctcaagagtcgagtcaccatatcaatagacacgaccaacaaccagttctccctgaagttgacctctgtgaccgccgcggacacggctgtatatttctgtgcgagaggttgggcccaacaagcgggagctacgtttgttggctggttcgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6895 JY8QFUQ01AAWUE No results +6896 JY8QFUQ01DABGE productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CNLHPYGDSSDYW in-frame + ctctggactcaccttcagtcgcctctggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtatagatagtgatgggaataacataatctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaaaacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtaaccttcatccctacggtgactcctccgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6897 JY8QFUQ01A4XPO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD5-12*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARDGSAHSSIYHYYYGMDVW in-frame + ctctggattcaccttcagttctcacactatgaactgggtccggcaggctccagggaaggggccggagtgggtctcaaccattggtactagaggtagatccatatactacgcggactcagtgaagggccgattcaccacctccagagacaacgccaagaaatcactttatctggatatgcacagcctgagagccgaggacacggctatctattactgtgcgagagatggcagtgcacactcgtcgatctatcattactattacggcatggacgtctggggccaagggaccacggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcacgcacccagccagatgggaacgtcgtcatcgcctgcctggtccagggcttcttcc +6898 JY8QFUQ01B8W2U productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6899 JY8QFUQ01DCFU5 productive Homsap IGHV3-30*12 F, or Homsap IGHV3-33*05 F 886 90.28 195/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDLYCSGGTCSDYW in-frame + tctggattcaccttcagtcagtactggatgtactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggctgtctattactgtgcgagagacctatattgtagtggtggtacctgcagcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6900 JY8QFUQ01AYD6Y unknown (see comment) Homsap IGHV3-7*02 F 114 59.52 50/84 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found cctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6901 JY8QFUQ01DFUCH productive Homsap IGHV3-7*01 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDPYKPGSGNPGFDYW in-frame + ctctggattcacctttagtgactatttgatgacttgggtccgccaggctccaggaaagggactggagtgggtggccaacataaaagaagatggacttgctacattctatgtggactctgtgagggaccgattcaccatctccagagacaacgccaagaactcactttatttgcaaatgaattacctgagagtcgaggacacggctgtttattattgtgcgagggatccctataaacctggttcgggcaatccgggctttgactactggggccagggagcgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6902 JY8QFUQ01AC5KS No results +6903 JY8QFUQ01CD4VE unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGV*QWL##DFDCW out-of-frame - stop codons ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6904 JY8QFUQ01BPD81 No results +6905 JY8QFUQ01C5EHB productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6906 JY8QFUQ01ATRRJ unproductive Homsap IGHV3-48*01 F 963 94.01 204/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-17*01 F 2 8 8 X 8.8.X [1.16.38.11] CARDGDSTVL#DYW out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'CA' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) cctctggattGcacctttagtaacCAtttgggatgaactgggtccgccaggctccgggaaggggctggaatgggttgcatacattagtagtgatggtagtaccctatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaaagactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagacggggactctacggtactcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6907 JY8QFUQ01A0XE3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 7 12 8.7.12 [1.17.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +6908 JY8QFUQ01DRSTV No results +6909 JY8QFUQ01B39P6 No results +6910 JY8QFUQ01B4O50 productive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgcgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6911 JY8QFUQ01CF31P unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*03 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F or Homsap IGHV3-9*01 F or Homsap IGHV3-9*03 F 83 51.54 67/130 nt 8 7 X 8.7.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcacctttagtgattatagaatgaattgggtccgccaagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +6912 JY8QFUQ01CC8BY unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt 97.33 219/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 X 10.9.X [1.17.38.11] CTRGSSRGGDMMRTTMS#DFW out-of-frame + in FR3-IMGT at codon 74 of V-REGION: 'T' (1 nucleotides at position 134 to 134 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaaTgtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcgggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +6913 JY8QFUQ01AA63Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDAVGLTRLFGDW in-frame + ctctggatttgtctttagtagatatgccatggcctgggtccgccaggctccagggcaggggctggagtgggtcgccagtattggcgggagtggtgataacacatactacgcggactccgtgaagggccggttcaccatctccagagacaactccaataacaaactgtttctgcaaatggacagtttgcgagccggggacacggccagatatttctgtgcgaaagatgcggtgggacttacccgactctttggtgactggggccagggaaccgtggtcagcgccgcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtccatcgcctgccctggtccagggcttcttccccca +6914 JY8QFUQ01ATUUQ productive (see comment) Homsap IGHV3-15*05 F 924 91.36 201/220 nt 90.0 198/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD6-13*01 F 1 7 10 10 7.10.10 [1.16.38.11] CATYSNKWSVFW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 94 of V-REGION: 'A' (1 nucleotides at position 188 to 188 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tctggattcaattcactaacgcctggatgagctgggtccgccaggctccggtaaggggctggagtgggttggccatattaaagccaacactgatggtgggacaacagactacgctgcacccgtgaaaggcagattcaccatctcgagagatgattcaaaagccacagtatatctgcagatgagcattAcggaaaaccgaagacacagccgtgtatttctgtgcaacctatagcaacaagtggagtgtcttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6915 JY8QFUQ01CG8LN unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD5-18*01 F 3 10 7 X 10.7.X [1.17.38.11] CARHSRLVRYFEF## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggcccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +6916 JY8QFUQ01A1ID6 No results +6917 JY8QFUQ01C1U8F unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGR## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggGggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtcggggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6918 JY8QFUQ01DINPB productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 852 87.73 193/220 nt 86.82 191/220 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD6-19*01 F 1 7 8 17 7.8.17 [2.17.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'A' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift) cagcctctggattcagtttagtacacatggcatgaactAgggtccgccaggctccagggaatgggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtcttctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6919 JY8QFUQ01AL1GZ productive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1007 94.64 212/224 nt Homsap IGHJ6*01 F (see comment) 180 76.19 48/63 nt Homsap IGHD4-11*01 ORF 3 8 10 18 8.10.18 [1.17.38.11] CVRHEGTPVSDVGGYGMDVW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtggctctgctatgcactgggtccgccaggtttccgggaaagggctggagtgggttggccgtattagaagcaaagcttacaattccgcgacagcatatgctgcgtcggtgaaaggcaggttcaccatctccagagatgattcaaagaacacggcgtatttggaaatgaacagtttgaagagggaggacacggccgtgtattactgtgtgagacatgaagggactccagtaagtgatgtaggtggatacggcatggacgtctggggtcaagggtccacggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +6920 JY8QFUQ01AM69R No results +6921 JY8QFUQ01BHL2X No results +6922 JY8QFUQ01DVCZ5 No results +6923 JY8QFUQ01CMFO6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6924 JY8QFUQ01A0P50 unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 920 90.95 201/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-8*02 F 2 10 7 X 10.7.X [1.17.38.11] CARLTDWWG##FDHW out-of-frame + stop codons tctctggtggctccatcagcggtacttctcattactggggctgggtccgccagcccccagggaaggggctggagtggattggcagtatctactctggtgggaccacctactacaacccgtccctcaagagtcgactcaccatgtccgtcgacacgtccaagaaccagatgtccctgcggctgagctctgtgaccgccgcagacacggctgtctattactgtgcgagactgacagactggtggggggcactttgatcactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +6925 JY8QFUQ01ANGDO unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 191 60.77 79/130 nt 8 6 X 8.6.X [1.17.11.X] null - No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +6926 JY8QFUQ01DCT1Z unknown (see comment) Homsap IGHV3-23*05 F 108 56.57 56/99 nt 8 6 X 8.6.X [1.17.X.X] null + No rearrangement found stop codons cctctggattcgtctttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt +6927 JY8QFUQ01A9XR5 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 927 92.17 200/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +6928 JY8QFUQ01DKX3B No results +6929 JY8QFUQ01CCW31 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKLGVAATTWNFFDYW in-frame + ctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6930 JY8QFUQ01AIVRQ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [2.17.38.11] CTREVGATDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatCgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6931 JY8QFUQ01DKN3S unproductive Homsap IGHV4-61*02 F 803 85.07 188/221 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-16*01 F 1 10 7 X 10.7.X [1.17.38.11] CAREHSSSIGGERELDS## out-of-frame + tgtctggtggccccatcagcagtagtggcttcgcctggacctggatccggcagaccgccgggaagggactggagtggatcggacgtgtttatggtagtgggaataccaattacagtccttccctccagagtcgagtcaccatatcagtagagacgtccaagaatcagttctccctgaggttgacttctgtgaccgccgcagacacgggcctatattactgtgcgagagaacatagtagttcgattggcggagagagagaacttgactcctggggccagggaacccgaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +6932 JY8QFUQ01B4XES productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6933 JY8QFUQ01DJ0QP unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 854 95.19 178/187 nt 94.65 177/187 nt 8 7 X 8.7.X [1.16.29.X] null + No rearrangement found in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctgggttcaacgtcagtagcgactacatgagctgggtccgccaggctccagggaaggggctggagtggtctcagttatttatggaggtggtagtacatactacgcagactccgtgaagggccgattcaccatgtccagagacaattccaagaacacggtgtatcttcagatgaatagcctgagag +6934 JY8QFUQ01BBKM0 No results +6935 JY8QFUQ01BMHXX unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.43 191/216 nt Homsap IGHJ2*01 F (see comment) 30 66.67 10/15 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcaaggactacttcccgaaccggtgacggtgtcgtggaac +6936 JY8QFUQ01B441S productive (see comment) Homsap IGHV3-7*01 F (see comment) 725 81.65 178/218 nt 80.73 176/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'T' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift); cctctggattcacctttagaagctatgccatgagttgGggtccgccaggccacagggaaggggccggagtgggtggccaacatatcccccagacggaatacgaaatactTttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6937 JY8QFUQ01DMDYG No results +6938 JY8QFUQ01AL76Y No results +6939 JY8QFUQ01CSOSY productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + tctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +6940 JY8QFUQ01B4PX2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc +6941 JY8QFUQ01BLIGP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6942 JY8QFUQ01C5UV3 No results +6943 JY8QFUQ01ANVMV unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 105 100.0 21/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattcactttcagtaa +6944 JY8QFUQ01AY6XT productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame + ctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6945 JY8QFUQ01C2W2V No results +6946 JY8QFUQ01B4IND No results +6947 JY8QFUQ01BED94 No results +6948 JY8QFUQ01CO5FZ unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 202 95.45 42/44 nt 8 X X 8.X.X [1.5.X.X] null - No rearrangement found ctctggattcaccttcagtagctactggatgcactgggtcccca +6949 JY8QFUQ01ANPDB unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 353 86.17 81/94 nt 8 5 X 8.5.X [1.17.X.X] null + No rearrangement found ctctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc +6950 JY8QFUQ01BY7G4 No results +6951 JY8QFUQ01AULA5 productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6952 JY8QFUQ01A1J72 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARVFSGVAAPPDSW in-frame - ctctggaatttcccttcaccagttactggatgcagtgggtccgccaagctccagggaaggggctggtctgggtctcacttagtaatagtgatgggagcactactacctacgcggacgccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatcttcaaatgaatcatctgagagtcgaggacaccgctgtatatttctgtgcgagagttttcagtggtgtcgctgctcccccggactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6953 JY8QFUQ01B4ZSG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ2*01 F 112 67.92 36/53 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVVWSLWYFDL## out-of-frame + tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggcccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtcgacggtgtcgtggaactc +6954 JY8QFUQ01CAGIU No results +6955 JY8QFUQ01CXWLV No results +6956 JY8QFUQ01BOO7X productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame - ctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6957 JY8QFUQ01BQMCE No results +6958 JY8QFUQ01DF7SD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 916 90.54 201/222 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [3.17.38.11] CARGHSYYVSSGPDY## out-of-frame - gcagcctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactgggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6959 JY8QFUQ01AZ4SQ No results +6960 JY8QFUQ01ACVY4 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 831 87.85 188/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame - ctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6961 JY8QFUQ01DADPQ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +6962 JY8QFUQ01CB0JI unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWGELSL#DYW out-of-frame - stop codons ctctgggtggctccatcagtagttactactggagctggatccggcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6963 JY8QFUQ01BKVAE productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6964 JY8QFUQ01BHBOZ No results +6965 JY8QFUQ01C7CUA No results +6966 JY8QFUQ01AEDSZ unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ2*01 F 130 71.7 38/53 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CARRGRCG*#YWYFDLW out-of-frame + stop codons tctctagtgactccatcagcagtactaattactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatgtatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgagacgggggagatgcggataactactggtacttcgatctctggggccgtggcacccctggtcactgtctcttcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +6967 JY8QFUQ01B4OHV No results +6968 JY8QFUQ01C1V23 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDLYGADDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); acctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaAaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6969 JY8QFUQ01CQ6HE productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARVRGGLSSGWYESLDYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagttcgaggaggtcttagcagtggctggtacgagtctcttgactactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaaccctt +6970 JY8QFUQ01CVKGA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccaccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctggctgcctggtcaaggactacttccccgaaccgtgacggtgtcgtggaactcag +6971 JY8QFUQ01AF8SZ productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 823 87.04 188/216 nt 86.57 187/216 nt Homsap IGHJ1*01 F (see comment) 188 84.62 44/52 nt Homsap IGHD1-26*01 F 1 8 7 13 8.7.13 [2.17.38.11] CVGVGVGSSVSFQYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); gcctctggattcactgtcaataacaactacatggGgttgggtccgccaggctccagggaaggggctggagtgggtctcgactatttattacggtggcaccacatattacgcagactccgcgaagggccgattcaccatctccagagacacctccaggaacacactttttcttcagatgaacagcctgagaagcgacgacacggctctatattattgtgtgggagtcggagtgggatcttcagtctccttccaatactggggccagggcacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +6972 JY8QFUQ01C6LUZ No results +6973 JY8QFUQ01C8AP7 unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 135 77.78 35/45 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found ctctggattcagcctcgccacttatagtatgagttgggtccgcca +6974 JY8QFUQ01AND8W productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.21 206/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'T' (1 nucleotides at position 142 to 142 in the user submitted sequence), (cause frameshift); tctctggtgGggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccTttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6975 JY8QFUQ01BEKRO productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 849 87.0 194/223 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 10 11 8.10.11 [1.17.38.11] CAISSDFYSTGYW in-frame - ctctggactcactttcagtgacgcctggatgacctgggtccgccaggttccagggaaggggctggagtgggttgcccatattagatggaactctgatgactggaccacagactacgctactcccgtgaagggcagattcaccatctcaaaagatatttcagagaacacgctgtatctacaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgattagtagtgatttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6976 JY8QFUQ01CS4ZH unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARKRVPGGNFLM#DYW out-of-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggaactttttgatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6977 JY8QFUQ01BRRHQ No results +6978 JY8QFUQ01A5ZX6 productive Homsap IGHV1-2*02 F 804 86.45 185/214 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD3-16*02 F 2 8 8 15 8.8.15 [0.17.38.11] CARHFCDTNDVCDFDIW in-frame + tggatacagcttcaccgacttttacattcattgggtgcgacaggaccctggacaagggcttgagtggatggggtggaccaaccctaaaaatggtggcacgttcattacgctgaagtttcagggcagggtcactatgtccagggacacgtccatgaccacagtctatatggagatgagcaggctgagatctgacgacacggccatttattactgtgcgagacatttttgtgacaccaacgacgtctgtgattttgatatctggggccaggggacaaaggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +6979 JY8QFUQ01DIQBL No results +6980 JY8QFUQ01CF6S7 productive (see comment) Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 393 91.49 86/94 nt 90.43 85/94 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD5-18*01 F 3 X X 15 X.X.15 [X.X.31.11] CARSDEEYSYGDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'ACTAT' (5 nucleotides at position 21 to 25 in the user submitted sequence), (cause frameshift); gtctggattcaccttcagtaACTATgagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatcggacgaggaatacagctatggggatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6981 JY8QFUQ01CA8X1 No results +6982 JY8QFUQ01A1RQZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6983 JY8QFUQ01DW561 No results +6984 JY8QFUQ01BXLHS productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccagccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6985 JY8QFUQ01C1UBU No results +6986 JY8QFUQ01C0A57 unproductive Homsap IGHV3-7*01 F 832 86.7 189/218 nt 83.94 183/218 nt Homsap IGHJ1*01 F 134 73.08 38/52 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDRPGGWALDY## out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 43 of V-REGION: 'T' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'ATG' (3 nucleotides at position 62 to 64 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); ctcctggattcaGtttttagtgacttttggatgcgActgggtccTgccaggcnccaggggaATGggggctggagtgggtggGcccacntgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacgGgctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactgggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctcccaagagcacctctggggggcacagcggccctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6987 JY8QFUQ01DCQ1T No results +6988 JY8QFUQ01DESYR productive (see comment) Homsap IGHV4-39*03 F 920 90.91 200/220 nt 90.0 198/220 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-14*01 ORF 2 10 7 12 10.7.12 [2.16.38.11] CTREGPYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 121 to 121 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 63 in the user submitted sequence), (cause frameshift) gtctctggtgactccatcagtaatactgattactactgggtctggatccgccagaccccaggaagggactggagtggattgggagtatcgatttcagtgggagcacctactacaacccgtGccctcaagagtcgagtcaccatatccatagacacgtccgagaaccggttctccctgaggttgacctctatgaccgccgcagacacggccgtctattactgtacgagagagggaccctactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6989 JY8QFUQ01BIDBG unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +6990 JY8QFUQ01C9ZA6 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGGFGAR#DYW out-of-frame - in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacatactGggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggttttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6991 JY8QFUQ01AFCRV productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); gtctggattcacgtttagtagAttttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6992 JY8QFUQ01AE5R0 No results +6993 JY8QFUQ01DBYPZ unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +6994 JY8QFUQ01DMVTY No results +6995 JY8QFUQ01BKSTZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaaggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +6996 JY8QFUQ01BPGKK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +6997 JY8QFUQ01A7BGY productive (see comment) Homsap IGHV3-48*01 F 1080 100.0 217/217 nt 99.54 216/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 101 of V-REGION: 'A' (1 nucleotides at position 206 to 206 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctAgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +6998 JY8QFUQ01CW0ME productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +6999 JY8QFUQ01AS1T0 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDAFEMW in-frame + ctctggattcatctttgatgattttggcatgaattgggtccgccaagctccagggaaggggctggagtgggtcgctggtatcagttggaatggtggcaaagcaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcaatgtctcttcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +7000 JY8QFUQ01BEHCJ No results +7001 JY8QFUQ01A1BXA No results +7002 JY8QFUQ01B7SR3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7003 JY8QFUQ01C3KDY productive (see comment) Homsap IGHV3-13*01 F 898 91.55 195/213 nt 91.08 194/213 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD4-11*01 ORF 3 8 7 17 8.7.17 [1.17.37.11] CAREVTRLTVPYYLYFDLW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 100 of V-REGION: 1 nucleotides (from position 200 in the user submitted sequence), (cause frameshift) ctctggaatcaccttcagtgactccgacatgcactgggtccgccaagctccaggagaaggtctggagtgggtcgcagctattggaactgctggtgatacatactatgcagactccgtgaagggccgattctccattaccagagagaatgccaagaactccttgtttcttcaaatgaacagcctgagagccggggacacgctgtttattattgtgcaagagaggtgactagacttactgtcccctattacttatacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaangtggtcgtcgcatgcctggtccagggcttcttcccccaa +7004 JY8QFUQ01DG9VD No results +7005 JY8QFUQ01AB51E productive Homsap IGHV3-48*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDMIIFGGALDNW in-frame - ctctggattcgccttcagtagttccagcatgaactgggtccgccagggtccagggaaggggctggagtggatttcacacattaggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggagcccttgacaactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7006 JY8QFUQ01AGUFW No results +7007 JY8QFUQ01BYQPY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame - ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7008 JY8QFUQ01CR7U0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 822 87.38 187/214 nt 86.45 185/214 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.37.11] CAKESLVRGVISYYFDDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 131 in the user submitted sequence), (cause frameshift) cctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctggttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7009 JY8QFUQ01DSDF6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactactcccgaccggtgacgtgtcgtggaactcag +7010 JY8QFUQ01BS28G No results +7011 JY8QFUQ01DTJ0Q unknown (see comment) Homsap IGHV1-2*03 F 83 57.35 39/68 nt 55.88 38/68 nt 8 X X 8.X.X [0.13.X.X] null - No rearrangement found in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) tggatacaccttcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7012 JY8QFUQ01BRUUS productive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 912 90.13 201/223 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 10 14 8.10.14 [1.17.38.11] CARVRGYYGGQYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtggctctgctatgcactgggtccgccaggtttccgggaaagggctggagtgggttggccgtattagaagcaaagcttacaattccgcgacagcatatgctgcgtcggtgaaaggcaggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7013 JY8QFUQ01CDPNO No results +7014 JY8QFUQ01BQHEC unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 493 83.57 117/140 nt 82.86 116/140 nt 8 8 X 8.8.X [1.16.12.X] null - No rearrangement found Low V-REGION identity (83,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag +7015 JY8QFUQ01AKNKF unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7016 JY8QFUQ01C31PA productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7017 JY8QFUQ01AI5J2 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 925 92.96 198/213 nt 92.02 196/213 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.16.38.11] CARAPRTATLLDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggcgactccatcagtggtcactactggagctggatcaggcagcccccaggaagggactgcagtggattggttacatctatcacCagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7018 JY8QFUQ01BRQVZ productive (see comment) Homsap IGHV3-9*01 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-21*02 F 3 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) ctctggattcactttgatgactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7019 JY8QFUQ01BRXHG unknown (see comment) Homsap IGHV3-23*02 F, or Homsap IGHV3-23*03 F or Homsap IGHV3-30*05 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*12 F 137 52.72 97/184 nt 8 7 X 8.7.X [0.17.28.X] null - No rearrangement found ctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7020 JY8QFUQ01A3OS9 productive Homsap IGHV4-39*02 F 834 86.82 191/220 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttc +7021 JY8QFUQ01AQT5C productive Homsap IGHV3-72*01 F 1093 98.67 222/225 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-15*01 F 1 8 10 8 8.10.8 [2.17.38.11] CLRPPRYDPW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gcctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7022 JY8QFUQ01A1QIB No results +7023 JY8QFUQ01AUB4Z No results +7024 JY8QFUQ01CUXQ0 productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7025 JY8QFUQ01BU35B productive (see comment) Homsap IGHV3-7*01 F 949 93.52 202/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 99 of V-REGION: 'G' (1 nucleotides at position 201 to 201 in the user submitted sequence), (cause frameshift); tctacattcacgGtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacaGcggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7026 JY8QFUQ01BL0B1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 747 82.49 179/217 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDRPAGKAEGYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacttttagtgattatgccatggcctgggtccgccaggctccagggaaggggctggaatgggtcggaagtattaatctcagtgttgatgacacatattacgcagcctccgtgaggagtcgcttcaccgtctccagagacaattccaagaacaccttctatttgcacatggccagcctgagagccgaagacacggccatatattattgcgcgaaagatcggccagccggaaaggctgaggggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7027 JY8QFUQ01BV2B3 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7028 JY8QFUQ01A3ZBL No results +7029 JY8QFUQ01BIDDX No results +7030 JY8QFUQ01A1UXZ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 750 83.64 179/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccccctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc +7031 JY8QFUQ01BPC6B No results +7032 JY8QFUQ01AFU74 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 903 91.59 196/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame + ttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7033 JY8QFUQ01AQ25R productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 870 88.64 195/220 nt 87.73 193/220 nt Homsap IGHJ3*01 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-16*01 F 2 10 7 12 10.7.12 [1.16.38.11] CARTYTYRNAFDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 31 of V-REGION: 'TGC' (3 nucleotides at position 20 to 22 in the user submitted sequence), (do not cause frameshift); in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 45 in the user submitted sequence), (cause frameshift) tctcgggtgactccctgagTGCcagtagtagtttctactggggctgggccgccagcccccagggaagggactggagtggattgggactgtttattatagtgggagcgcccactacaatccgtccctcaagagtcgagtcgccatatccgtggacacggcccagaaccaggtctccctgacgttgaactctgtgaccgccgcagacgccgctgtctatttctgtgcgagaacttatacttatagaaatgcttttgacgtctggggccaggggacattggtcgctgtgtcttcagcatccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7034 JY8QFUQ01BRGSI productive Homsap IGHV3-48*01 F 999 95.85 208/217 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARVGATLSFDVW in-frame + ctctggattcaccctcagtagctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtattagtagtggtaccatatactatgcagactctgtgaagggccgattcaccatctccagggacaatgccgagaactcactgtatctgcaaatgagcagcctgagagccgacgacacggctgtgtattactgtgcgagagtgggagcgacgctttcttttgatgtctggggccaagggacaacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +7035 JY8QFUQ01BQ9KW productive (see comment) Homsap IGHV4-61*02 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 10 6 16 10.6.16 [1.17.38.11] CAIERSRSIGGDGQFDFW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 102 in the user submitted sequence), (do not cause frameshift) tctctggtggccccatcagaggcggtggtttctactggacctggctccggcagtccgccgggaagggcctggagtggatcggacgtatttatgacagtggcagtgactacaatccttctctcaagagtcgagtcaccatgtcagtagacacgtccaagagccagttctccctgaggctgagttctgtggccgccgcagacacggccgtttacttctgtgcgatagaacgtagtagatcgattggcggagacggacaatttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +7036 JY8QFUQ01A6UEX productive Homsap IGHV3-21*04 F 990 95.39 207/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame + ctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7037 JY8QFUQ01BMUUJ productive (see comment) Homsap IGHV3-7*01 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.38.11] CSRLLEEW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'A' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); cctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggAagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7038 JY8QFUQ01CVWSV productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7039 JY8QFUQ01DGC1Z productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 901 90.41 198/219 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [2.17.38.11] CARADDYGDYPEFW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gcctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7040 JY8QFUQ01BDF0B No results +7041 JY8QFUQ01AQ3T9 productive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [1.17.38.11] CARVIPGRGNYAFDVW in-frame + ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7042 JY8QFUQ01AVH5A No results +7043 JY8QFUQ01AGKQB productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD2-15*01 F 2 8 8 12 8.8.12 [1.17.38.11] CAKGGGNGDLDYWG in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccaggggaaccctgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagnacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +7044 JY8QFUQ01BBZW6 No results +7045 JY8QFUQ01BMJGI productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 281 81.4 70/86 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWHYFENW in-frame - Low V-REGION identity (81,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggcactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7046 JY8QFUQ01CRJXJ productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 6 15 8.6.15 [2.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcagtgatagttacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcgattatttataggggaggaccacatattatgccgactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +7047 JY8QFUQ01B5EMZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7048 JY8QFUQ01C1LP7 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1004 95.87 209/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +7049 JY8QFUQ01A3U1I productive Homsap IGHV3-11*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame + ctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaagggttcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcaatgcctggtccagggcttcttcccc +7050 JY8QFUQ01AE6UZ productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKEEFDTGWTQPGDW in-frame + ctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7051 JY8QFUQ01B2R53 unknown (see comment) Homsap IGHV3-7*01 F 1031 96.79 211/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +7052 JY8QFUQ01BNMS9 productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYYHYDTFGDYW in-frame + ctctggattcacttttagcaactattggatgacctgggttcgccaggctccagggaaggggctggagtgggtggccaacataaaacaacatggaggtgaaatgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcaatatatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattatcattatgacaccttcggcgactattggggccagggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +7053 JY8QFUQ01DP55Y productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 911 90.5 200/221 nt 89.59 198/221 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD1-14*01 ORF 3 10 7 13 10.7.13 [1.17.38.11] CARHLQYNRHGFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 175 to 175 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtagtcattactactggggctggatccgccagaccccaggaaAaggggctggagtggcttgggacaatctattatagcggaagcgcctacatcaacccgtccctcaagagtcgagtcaccatttccgttgacatatctaagaaccagttctccCctgaggctgacctctgtgaccgccgcagacacggctgtctattactgtgcgagacacctgcaatataatcgacatggttttgatttctggggccaggggacaacggtcaccgtctcttcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7054 JY8QFUQ01CIGT5 No results +7055 JY8QFUQ01AG3IU productive Homsap IGHV3-9*01 F (see comment) 789 84.55 186/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [2.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release agcctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7056 JY8QFUQ01BB0BB unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 639 76.96 167/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (76,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7057 JY8QFUQ01CHKWD productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 853 89.2 190/213 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [X.17.38.11] CARLGQLALDYW in-frame - gggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7058 JY8QFUQ01C0MXG unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 501 84.78 117/138 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (84,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaact +7059 JY8QFUQ01BWVM6 productive Homsap IGHV3-11*01 F 938 93.87 199/212 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 7 8 13 7.8.13 [X.17.38.11] CARDLQLGDDSGFSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gattcaccctcagtgactactacatgacttggatccgccaggctccagggaaggggctggagtgggtttcgtacattagtagtctcactagttccatatattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactatatctgcaaatggacagcctgagagccgaggacacggccgtgtattactgtgcgagagatcttcagctgggggatgatagtgggttttcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7060 JY8QFUQ01APENB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7061 JY8QFUQ01A4BVQ No results +7062 JY8QFUQ01CHFPQ unknown (see comment) Homsap IGHV4-61*02 F (see comment) 707 80.73 176/218 nt 80.28 175/218 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (80,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggGggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgccctttgtacacaccgcccgtcgctactaccgattggatggtttagtgaggccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7063 JY8QFUQ01CQFLG productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 920 90.95 201/221 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 10 7 18 10.7.18 [1.17.38.11] CARSAYCGADCYSADYLQHW in-frame + tctctggtggctccgtcagcagtaggggttactactggaactggatccgccagttcccagggaagggcctggagtggattgggaacatcttttacagtgggggcacctacgacaacccgtccctcaggagtcgaatttctatatcattagacacgtctaagaaccaattctccctgaagttgacctctatgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgntgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +7064 JY8QFUQ01AF76F No results +7065 JY8QFUQ01DW1F3 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7066 JY8QFUQ01AMBQU No results +7067 JY8QFUQ01AMJ07 productive (see comment) Homsap IGHV3-33*05 F 840 88.32 189/214 nt 87.38 187/214 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'N' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) gtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagtNtttggcatctggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7068 JY8QFUQ01C1OYL productive (see comment) Homsap IGHV1-18*01 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD1-20*01 F 1 8 8 11 8.8.11 [0.17.38.11] CARVIRTNWLDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tggttacacctttactacctatgGgcgtcacctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatgataatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacggccgtatattattgtgcgcgagtaattcgaaccaactggctcgacccctggggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +7069 JY8QFUQ01AR065 No results +7070 JY8QFUQ01BOHG3 No results +7071 JY8QFUQ01B4Y1N productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGDYYDSGGLDYW in-frame + tccggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtgattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7072 JY8QFUQ01C6FUD productive Homsap IGHV3-33*02 F, or Homsap IGHV3-33*03 F 148 65.43 53/81 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 X X 14 X.X.14 [X.X.27.11] CATDDSNGWDEVADYW in-frame - gcctctggattcaccttcagctcccattggatgagctggatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7073 JY8QFUQ01A8S53 productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame - gtctggattcacatttagaagctattccatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7074 JY8QFUQ01AJNWH unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 984 93.72 209/223 nt 93.27 208/223 nt 8 10 X 8.10.X [1.17.38.X] null + No rearrangement found in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtaacgcctggatgatctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagaccaaagctgatggtgcgacaacagactactctgcacccgtgagaggcagattcatcatctcaagagatgattcaaaaaaTcatggcgtttctgcaaatgaacagcctgaaaaccgaggacacagccctttattactgtacctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccccta +7075 JY8QFUQ01A1AL3 productive Homsap IGHV4-61*02 F (see comment) 596 74.66 165/221 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD3-10*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARECSNSKVGPRALDSLG in-frame + Low V-REGION identity (74,66% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tttctggtggcccgatcaaaagtcctgattaccattggacgtggatccggcagcccgccgggaagggactggagtgggtcggacgtgtctatatgactggttatgtcgaccacaatccatccctctccgggcgtctcaccatgtctatcgacacctcgaagaatcaattttctatgacattgacctctgtgaccgccgcagacacggccctatatttttgtgcgagggagtgtagtaattcgaaggtcggaccgagagcgcttgattccctgggggccccgggaagtctggtcaccgtatcatcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7076 JY8QFUQ01DRQBM unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 87.56 190/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7077 JY8QFUQ01AD74T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [1.17.38.11] CVRYDYSRLHRSNYFGPW in-frame + ctctggattcaccttcatcagttatggcatgagttgggtccgccagtttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7078 JY8QFUQ01BVWJB No results +7079 JY8QFUQ01B89F3 productive Homsap IGHV3-11*01 F (see comment) 764 84.19 181/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [0.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7080 JY8QFUQ01AFRV4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +7081 JY8QFUQ01CN5CY No results +7082 JY8QFUQ01BLUX0 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.17 200/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGYHGPFDS## out-of-frame + ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacacatactactcagactccgtgaggggccggttcaccatctccagagacaacgccaagaacacgatgtatctgcaaatgaacaccctgagagacgaggacacggccgtctatttctgcgcgaaaggttaccacggcccctttgactcttggggccggggcaaccctggttaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +7083 JY8QFUQ01BP937 No results +7084 JY8QFUQ01ASAFA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7085 JY8QFUQ01CWIEU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 840 88.32 189/214 nt 87.85 188/214 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 7 15 8.7.15 [0.17.38.11] CAKVYTGAWGDPNFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) ctggattcagctttagcaactttgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtactttagcacccattatgccgactccgtgaagggccgcttcaccatctccagagacaatttcaggagcaccttatatctgcagatgaacaacctgagagccgacgacacggccatatattactgtgcgaaagtgtacaccggtgcctggggggatcctaattttgactcctggggccagggaaccctggtcaccgtctcctcagcattcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7086 JY8QFUQ01ASX49 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 400 77.61 104/134 nt 76.12 102/134 nt 7 6 X 7.6.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (77,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7087 JY8QFUQ01AKWRV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7088 JY8QFUQ01AIQZV productive Homsap IGHV3-48*01 F 963 94.01 204/217 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARVGATLSFDVW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtattagtagtggtaccatatactatgcagactctgtgaagggccgattcaccatctccagggacaatgccgagaactcactgtatctgcaaatgagcagcctgagagccgacgacacggctgtgtattactgtgcgagagtgggagcgacgctttcttttgatgtctggggccaagggacaacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7089 JY8QFUQ01BPR4U productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 707 80.73 176/218 nt 80.28 175/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARYRVGDSLYYGLDGW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 59 of V-REGION: 'ACT' (3 nucleotides at position 90 to 92 in the user submitted sequence), (do not cause frameshift); cctctggattcattttagaaaattttgccatgagttggctccgccaggcaccagggaaggggctggaatgggtctcgactatcagcagcACTagtggtgacacggcatattactcagactccgtgaggggccgcttttccatctccagagacaactccaagagcactctgttcttgcagatgaacagcctgagtgccgaagacacggccatttactactgtgcgagataccgtgtgggtgacagtctctactacggtttggacggctggggccaagggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7090 JY8QFUQ01CCNJV productive Homsap IGHV3-13*01 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame - agcctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattgacactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7091 JY8QFUQ01BTRXA No results +7092 JY8QFUQ01CY676 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 903 91.59 196/214 nt 89.72 192/214 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.16.38.11] CARAPRTATLLDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'GA' (2 nucleotides at position 108 to 109 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'G' (1 nucleotides at position 138 to 138 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccaggaagggactgcagtGggattggttacatctatcacagtgggagcaccaactacGAacccctaccctcgagagtcgagtctccaGtttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7093 JY8QFUQ01DHXAX No results +7094 JY8QFUQ01C9NLW productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARAAGAGGKGGMDAW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcgccttcagtacttatggcataagttgggtccgccaggctccagggaaggGggctggagtgggtctcatccatcagtagtggcggtggttacatacactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaattcagtgcatctggaaatgaacatcctgagagccgaggacacggctgtgtactattgtgcgagagcggccggcgcaggaggtaaaggcggtatggacgcctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +7095 JY8QFUQ01C8NA6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 497 84.17 117/139 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (84,17% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc +7096 JY8QFUQ01APNF7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctncctggtcaaggactcanttccccgaaccggtgacggtcgtgcgtggaactcag +7097 JY8QFUQ01BBN1F productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7098 JY8QFUQ01A9JBF unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CGKPIVGATGREMPVSL# out-of-frame + ctctggattcacctttagcaactatgccatgaactgggtccgccaggttccaggggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttccctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +7099 JY8QFUQ01DQ9J1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1036 97.26 213/219 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - gcctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7100 JY8QFUQ01BE9YX No results +7101 JY8QFUQ01CE6FY No results +7102 JY8QFUQ01C315L productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggacatccag +7103 JY8QFUQ01BT8R0 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 80 51.13 68/133 nt 8 6 X 8.6.X [1.17.12.X] null + No rearrangement found ctctggattcacctttggcagctatatcatgagctgggtccaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7104 JY8QFUQ01C61HC productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 809 86.51 186/215 nt 86.05 185/215 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.16.38.11] CVRDSGPSGYARYESMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) tctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggaggggcgtggagtggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7105 JY8QFUQ01AUMIQ productive Homsap IGHV3-13*01 F 976 94.91 205/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame - gcctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7106 JY8QFUQ01C92K1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7107 JY8QFUQ01B043H No results +7108 JY8QFUQ01A889C No results +7109 JY8QFUQ01A9KO3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +7110 JY8QFUQ01CDKHU productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 900 90.78 197/217 nt 89.86 195/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.16.38.11] CARRSYCGGDCYPSYWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggctggagtggatggggatcatctatcctggtaactctgagaccaAaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7111 JY8QFUQ01CA2BM No results +7112 JY8QFUQ01BIIYS No results +7113 JY8QFUQ01CE8KX unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGAGAEGKGGMDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); ctctggattcaccttcCaaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctgggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7114 JY8QFUQ01BQQQR productive Homsap IGHV1-69*04 F, or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69*10 F or Homsap IGHV1-69*14 F 822 87.38 187/214 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [0.17.38.11] CAIPFSSSSAWFDPW in-frame + tggaggcaccttcagcagctatgtcatcagctggctgcgacaggcccctggacaagggcttgagtggatgggacatgtcattcctatgtttggtgtatctaacctcgcgcagaggttccagggcagagtcacaataaccgcggacacatccacgaccacagcctacatggaggtgaccaggctgagatctgaagacacggccgtctattattgtgccataccattcagcagctcgtcggcctggttcgacccctggggccagggaaccctggtcacgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7115 JY8QFUQ01A27VW unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-7*02 F 103 58.75 47/80 nt 8 X X 8.X.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7116 JY8QFUQ01AIUE1 No results +7117 JY8QFUQ01DERL0 productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7118 JY8QFUQ01BD4SW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccgaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcttccccgaaccggtcgacggtgtcgtggcaactcag +7119 JY8QFUQ01BCD33 productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7120 JY8QFUQ01ACU3P unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 890 88.39 198/224 nt 87.5 196/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-14*01 ORF 1 8 10 X 8.10.X [2.17.37.11] CTADVPSPLAQ#DFW out-of-frame - in FR3-IMGT at codon 76 of V-REGION: 'A' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) gcctctggattcactttcaatggcgcctggatgaactgggtccgccaggctccagggaagggtctggagtgggttgcccgtataaaaacttttggtgaaggtgggacaacagactacgctgcacccgtgaaaggcagattAcgtcatctcaagagacgattcaaaaaaaggctgtatctgcagatggacagcctgagaatcgaggacacagccaagtattactgcaccgcagatgtcccgtcaccattagcgcaaatgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7121 JY8QFUQ01ARGUC unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame + ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +7122 JY8QFUQ01AXW3W unknown (see comment) Homsap IGHV3-7*02 F 177 78.95 45/57 nt 8 X X 8.X.X [1.10.X.X] null + No rearrangement found tctggattcaacttcagaacctattggatgggctgggtccgccaggcttcttcccca +7123 JY8QFUQ01BFUH9 unknown (see comment) Homsap IGHV1-2*03 F 83 57.35 39/68 nt 55.88 38/68 nt 8 X X 8.X.X [0.13.X.X] null - No rearrangement found in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) tggatacaccttcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7124 JY8QFUQ01CCYZD productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 10 7 17 10.7.17 [1.16.38.11] CVRLDYYGSGSSYSGLDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) gtctggtggctccatcagtggtactccttactactggggctggatccgccagcccccaggtaagggctggagtggattgggcatgtatatcacagagggaccacctactacaacccgtccctcaagagtcgagtcgccatatccgtagacacgtccgagaaccggttctccctgcagttgaactctgtgaccgccgcagacacggctgtatattactgtgtgagactggattactatggttcgggaagttcttatagtggccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +7125 JY8QFUQ01BOLNO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7126 JY8QFUQ01BHQVJ unproductive (see comment) Homsap IGHV4-61*08 F 848 87.33 193/221 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-15*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARDFGYCSGENCNVP* in-frame + stop codons tctctggtgactccgtcagtagtggtgactattactggacgtggatccggcagctcccagggaagggactggagtggattggatatatgacttccggtgggacaaccaagtacaattcctccctcaagagtcgagccaccatatcagtggacacgtccaagaatcaactgtccctgacgttgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagagatttcggatattgtagtggtgagaactgcaatgtaccttgaggccagggaaccctggtcaccatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +7127 JY8QFUQ01B508J productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-3*02 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGPGGGWYAEQW in-frame + gtctggattcagtttcagtgactatgccatgcactgggtccgccagactccaggcaaggggctggagtgggtggcagttatttcatatgatgggagagagaagtactatgcagactccctgaagggccgattcaccacctccagagacaactccaagaaaatgctgtatctccaagtgaatagcctgagacctggagacacggctgtgtattactgtgcgaaagatgggccggggggtggctggtacgctgagcagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7128 JY8QFUQ01CNTYE No results +7129 JY8QFUQ01BXS1D productive Homsap IGHV4-34*06 F (see comment) 701 80.84 173/214 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 14 8.7.14 [1.17.38.11] CSRGGQSAGWHSFEAW in-frame + Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tccatggtgggtccctcaggggttacccctggacctggatccgccacaccgcagagaagggactggagtggattggtcaaatcaatagtgatggaaggacaacctacaactcggccctcatgggtcgagtcaccatttcaacagacacatccaagaatcagttctcgctgactgtggtttctgttgtcgccgcggacacggcaatgtattattgttcgagaggaggccaaagtgctggctggcactcctttgaagcctggggccagggaacccaggtaatcgtcacctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +7130 JY8QFUQ01CP3RW No results +7131 JY8QFUQ01BMZ10 unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 879 89.09 196/220 nt 87.73 193/220 nt Homsap IGHJ1*01 F 152 76.92 40/52 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [2.17.38.11] CARVGTFNWF#PW out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'T' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); ggcctctggattcaGattttgcagattatggcatgggctgggtccgccaacttccagggaaGggggctggaatgggtcggtggtgttaattggaatTgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7132 JY8QFUQ01CHAMB No results +7133 JY8QFUQ01BBC3I No results +7134 JY8QFUQ01C5AWT productive Homsap IGHV3-48*01 F 1085 99.54 217/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASIFGVVPLGNYYYGMDVW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca +7135 JY8QFUQ01C9L8S unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +7136 JY8QFUQ01DHC2K No results +7137 JY8QFUQ01B4AIN productive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 831 87.38 187/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARVGGTHYHYGVDVW in-frame + tggaggctccttcagcatgtatgacatcagctgggtgcgacaggcccctgggcaagggcctgagtggatgggagcgatcaaccctgtctttcgtatagcgaattacgctcagaggttccagggtagagtcaccattatcgcggacgactctacgagcacagcctacatggagctggacagcctgacgtctgaggacacggccgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +7138 JY8QFUQ01BLJ3D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7139 JY8QFUQ01CNG9Q productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctgggtcccacggggttcttcccccag +7140 JY8QFUQ01CQAMY productive (see comment) Homsap IGHV3-7*01 F 899 91.16 196/215 nt 90.7 195/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 8 14 7.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 3 nucleotides (from position 12 in the user submitted sequence), (do not cause frameshift) cctctggattactttacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7141 JY8QFUQ01CEPL7 productive Homsap IGHV2-5*02 F 1062 93.03 227/244 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 2 10 7 14 10.7.14 [9.17.38.11] CGHIRAELSTACHALW in-frame + gaccctcacgctgacctgcaccttctctgggttttcactcgacactattggaatgggtgtgggctgggtccgtcagcccccaggaaaggccctggagtggcttgcacttatttattgggatgatgataagcgctacacctcatctctgaagaccagactcagcatcaccaaggacacctccaaaaaccaggtggtcctcacaatgactaacatggaccctttggacacagccacatacttctgtggacacattagggcggaacttagcaccgcctgccatgccttgtggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttcccc +7142 JY8QFUQ01CPVAW No results +7143 JY8QFUQ01C6Y2R productive Homsap IGHV3-7*01 F 981 94.93 206/217 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDPYNGGGYGAFDIW in-frame + ctctggattcacctttagtaataattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacatcaagcaagatggaagtgagaaagtctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgcaaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagacccctataatggtggtggttatggtgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggacgtggtcatcgcctgcctggtccagggcttcttccccc +7144 JY8QFUQ01DPW6S productive Homsap IGHV3-11*01 F, or Homsap IGHV3-48*01 F or Homsap IGHV3-48*03 F or Homsap IGHV3-48*04 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAIEHTLPSGQGLGIEYFW in-frame + cctctggattcaccttcagtatctatgccatgacctgggtccgccaggctccagggaaggggctggagtggatttcatttatcactgataggggtagtacccaatactacgcagactctgtgaagggccgattcaccgtctccagggaccaagccaagaactcactgtatctacaaatgaacaacctgagagccgaggacacggccttatattattgtgcgatcgagcatacccttccgtccggacagggattagggattgaatatttctggggccagggaaccctggtcatcgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagcatgggaacgcggtcgtcgcatgcctggtccagggcttcttccccca +7145 JY8QFUQ01B2MWK No results +7146 JY8QFUQ01AM249 productive (see comment) Homsap IGHV3-30*13 F (see comment) 224 76.25 61/80 nt 75.0 60/80 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 1 X X 14 X.X.14 [X.X.26.11] CAKDLFQVSTTYFDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (76,25% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 87 of V-REGION: 12 nucleotides (from position 39 in the user submitted sequence), (do not cause frameshift) cctctggattcaccttcagtgactatcacatgtactggatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttcccccttggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7147 JY8QFUQ01DNKS2 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 885 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [2.16.38.11] CARAPRTATLLDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 42 of V-REGION: 2 nucleotides (from position 40 in the user submitted sequence), (cause frameshift) gtctctggcgactccatcagtggtcactactggagctggtcagcagccccaggccaagggaGctgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7148 JY8QFUQ01CKYI5 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CAKEGDGSVIPSPVPEWQ#FDSW out-of-frame + stop codons Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttgacagccatgccatgcactgggtccgtcgggctccagggaaggggctggagtgggtctcggcagttagtggtggtggccattatacatactacgcgcgctccgtgaagggccgatttaccatatccagggacaattcccgaaacatggtgtatttggagatgactggcctgacagccgaggacacggccgtatattattgtgcgaaagagggagacggatcagtgatcccgtctcctgttcctgagtggcaaatttgactcctggggccagggaaccctggccacggtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccc +7149 JY8QFUQ01CUYQI productive Homsap IGHV3-21*04 F (see comment) 657 78.34 170/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVRLFTSDGVRGDYW in-frame + Low V-REGION identity (78,34% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggtttcatcttcagtcacttcagcatgaactgggtccgccaggctccaggaaagggcctggagtggatcgccgacatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcgacgatacggccacctattattgtgtgaggctcttcaccagcgatggagtgagaggcgactactggggccagggcgcccgggttctcgtctccgcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7150 JY8QFUQ01C7DZ2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTKTRAFYYGSGSDGW in-frame + cctctggattcacctttagtagctatgccatcaactgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggcactacatactacgcagactccatgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtacaaaaactcgggcgttttactatggttcggggagtgatgggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7151 JY8QFUQ01BRAPP No results +7152 JY8QFUQ01CN5MD productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7153 JY8QFUQ01C48DS productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7154 JY8QFUQ01DW4VZ productive (see comment) Homsap IGHV3-48*02 F (see comment) 726 80.91 178/220 nt 80.0 176/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [2.17.38.11] CARSTDGYYDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 27 of V-REGION: 'GA' (2 nucleotides at position 10 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); agcctctggGAttcccccttcaatatatggagcatgaattgggtccgccaggctcCcggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7155 JY8QFUQ01BXDOJ No results +7156 JY8QFUQ01A8IP5 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 916 92.49 197/213 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CASQDYGEEGPDDD##FDIW out-of-frame - stop codons tctggtgcctccatcagtagttactactggagttggattcggcagcctccagggaagggactggagtggattgcttatatctcttacagtgggagggccaactacaacccctccctcaagagtcgagtcaccatgtcctcagacacgtccaagaaccaggtctccctgaagctgacgtctgtgaccgctgcggacacggccgtgtattactgtgcgagccaagactacggtgaagaggggccagatgatgatgccttttgatatctggggtcgagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7157 JY8QFUQ01C36E5 No results +7158 JY8QFUQ01DKHUQ productive (see comment) Homsap IGHV3-33*04 F (see comment) 706 81.02 175/216 nt 80.56 174/216 nt Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD4-17*01 F 3 8 8 8 8.8.8 [1.16.38.11] CARDTFGTTG in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) atttggattccctttcagcgactatggcatgcactgggtccgccaggctccagacaagggactagaaatgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatacttttgggactactggggccaggggaacccaggtcatcgtctcttcagcctccaccaaggggcccatcggtcttccccctggcacctcctccaagagcactctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7159 JY8QFUQ01CY2QM productive (see comment) Homsap IGHV4-61*07 F (see comment) 736 83.1 177/213 nt 82.63 176/213 nt Homsap IGHJ2*01 F 175 81.13 43/53 nt Homsap IGHD3-9*01 F 2 8 7 12 8.7.12 [2.17.38.11] CAREATYYDAFDVW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (8 AA in JY8QFUQ01CY2QM ; 10 AA in Homsap_IGHV4-61*07), and low V-REGION identity (83,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 64 of V-REGION: 'CAAA' (4 nucleotides at position 98 to 101 in the user submitted sequence), (cause frameshift); gtctctggcggctccgatcgggagttactactggacctggatccggcagtctccagggaaggggctggagtggattggatatagccacagcagtgggCAAAaccaattataagtacccttccctcaagagtcgagtcaccatatcaatagacacgtccaagaaccagttctccctgcagctgacctctgtgaccgctgcggacacggccatatattcctgtgcgagagaagcaacttactatgatgccttcgatgtctggggccgtggcacccaagtcagtgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7160 JY8QFUQ01DWM6Q unproductive Homsap IGHV3-9*01 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKDWPSSGWSHFE#L out-of-frame - gcctctggattcacctttgatgagcatgccatgcactgggtccggcaagttccggggaagggcctggagtgggtctctggtgttacttggaatagtggtgtcatagactatgcggactctgtgaagggccgattcaccatctccagagacaacgccaggaattccctgtatctacaaatgaacagtctgagaactgatgacacggccttctatttctgtgcaaaagattggccgagcagcggctggtcccattttgaggcttgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7161 JY8QFUQ01AL5WH productive (see comment) Homsap IGHV3-7*01 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); tctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagaCgggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7162 JY8QFUQ01AYR54 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame - tctggagttcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +7163 JY8QFUQ01BH2XD No results +7164 JY8QFUQ01CYD54 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7165 JY8QFUQ01BJL8P No results +7166 JY8QFUQ01AKY8Y productive (see comment) Homsap IGHV3-48*01 F (see comment) 744 83.89 177/211 nt 82.94 175/211 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [0.17.38.11] CSRDGRRGYDLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,89% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 80 in the user submitted sequence), (do not cause frameshift) tggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtGgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7167 JY8QFUQ01CQX10 productive Homsap IGHV3-23*05 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKSTGHSGWYPFDNW in-frame + ctctggattcacattcagcaattatgccatgggctgggtccgccaggctccagggaaggggctggagtgggtcgctgctattgatggcagtggtgaaagaactcactatgcagactccgaacagggccgcgtcaacatctctagagacaattccaagaacatgatatatgtgcaattgagcagcctgagagccgaggacacggccatgtattactgtgtgaagtccaccgggcacagtggctggtatccctttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttccttcccccga +7168 JY8QFUQ01AX6Q1 productive (see comment) Homsap IGHV3-30*07 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVTERGGGLLRYLDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagccatgctatgcactgggtccgccaggctccaggcaaggggctagagtgggtggGgggttatatcatctgatggaagtaatgaatactatgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgcgagacgacgacacggccatttactactgtgtgacagagaggggcgggggcctattacgatatttggacttatggggcctgggaactcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7169 JY8QFUQ01CJ0EA productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD3-9*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKAYDDVLTSYYIAAFHYSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgccatgcattgggtccgccaggctccaggcaaggggccggagtgggtggcagttatatcatatgatggaagtcataaagactatgcagcctccgtgaagggccgattcaccatctccagagacaattccaagagtacgttgtatctgcaaatgaacagcctgagacctgaggacacggctttatattcctgtgcgaaggcatatgacgatgttttgacttcttattacatagcagcttttcattactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag +7170 JY8QFUQ01BWAC8 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 289 65.16 101/155 nt 8 8 X 8.8.X [1.17.17.X] null + No rearrangement found Low V-REGION identity (65,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatatgaacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7171 JY8QFUQ01C8VGH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7172 JY8QFUQ01CMLZZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKHTLDYGPQYTMDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagagactatgtcatgagctgggtccgtcaggctccagggaaggggctggagtgggtctcaagtatcagtgatggaggtaatacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacgccctgtatctgcaaatgaacagcctgagagtcgaggacacggccatatattactgtgcgaagcatacacttgactacggcccgcagtacactatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7173 JY8QFUQ01BI2OG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1075 100.0 216/216 nt 99.54 215/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [1.17.37.11] CAKIHGSCSSTSC##NWFDPW out-of-frame + in FR3-IMGT, from codon 102 of V-REGION: 2 nucleotides (from position 210 in the user submitted sequence), (cause frameshift) cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtattactgtgcgaaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7174 JY8QFUQ01BKTDB No results +7175 JY8QFUQ01CWM9J No results +7176 JY8QFUQ01C50UA productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7177 JY8QFUQ01C528X productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 718 82.16 175/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDWGGSFDRYYFDYW in-frame + Low V-REGION identity (82,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release caccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +7178 JY8QFUQ01AS9PX productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDPFIAATGRPWYFDNW in-frame + tctggattcaccttcagtagttatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtgataaatactatgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtttctgcaaatgaacagcctgagaagtgaagacacggctgactattactgtgcgaaagacccatttatagcagcaactggccgcccctggtattttgacaactggggccagggagccctggtcaccgtcttctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7179 JY8QFUQ01BZ5XE productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 780 84.09 185/220 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFESW in-frame + Low V-REGION identity (84,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ttccggtgactccatcaccagtactaattattactggggctgggtccgccagtccccagggaagggtctggagtggattggaagtgtctattatcgggggacccagtacctcaacccgtctctccacaatcgagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtcttttggagtgataattgttaactactttgagtcctggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +7180 JY8QFUQ01CS9RD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCFNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctttaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7181 JY8QFUQ01B5UAN No results +7182 JY8QFUQ01BXDTL No results +7183 JY8QFUQ01A0L0Z productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 838 87.21 191/219 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD2-8*01 F 3 8 8 16 8.8.16 [2.17.38.11] CAKGGGTFGLRGYGMDVW in-frame - Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) gcctctggattcaccttcagttcttatggcatgcactgggtccgccaggctccaggcaaggggctgcagtgggtggcattcatatcgtatcatggagatactaaagactatgcagagtccgtgaagggccgactcaccatctccagagacaattccaagaacaaattatatttacaaatgaggagtctgacaagtgaggacacggctgcctattactgtgcaaagggcgggggaacttttggcctaagggggtacggcatggacgtctggggccacgggaccacggtcatcgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctgctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7184 JY8QFUQ01CMMBR productive Homsap IGHV3-64*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + cctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7185 JY8QFUQ01BV0PE No results +7186 JY8QFUQ01C5YHG productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 962 94.42 203/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [0.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7187 JY8QFUQ01DNZE4 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1005 95.45 210/220 nt 95.0 209/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); ggcctctggattcagcttGcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7188 JY8QFUQ01AUV1R unproductive (see comment) Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 X 10.7.X [1.17.38.11] CARQGA**WTLE#DYW out-of-frame + stop codons ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggcatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7189 JY8QFUQ01AV0AZ unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 467 70.92 139/196 nt 8 7 X 8.7.X [1.17.32.X] null - No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AV0AZ ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (70,92% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7190 JY8QFUQ01CLRMU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +7191 JY8QFUQ01AF7WD No results +7192 JY8QFUQ01A8SUE No results +7193 JY8QFUQ01CRX6K productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 783 84.79 184/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 169 82.0 41/50 nt Homsap IGHD4-17*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDRLNGDYTFGAFDLW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtctcctacataagtcgtctgagtcgccaaatatatgtcgctgacccagtgaagggccgattcaacatctccagagacaacgccaagaattcactgtatctgcaaatgaacaacttgcgggtcgaagacacggctgtgtatttttgtgccaaagatcgcctgaacggtgactacacattcggcgcatttgatctgtggggcccagggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccaggtgacggtgtcgtggaaactc +7194 JY8QFUQ01BOSQL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7195 JY8QFUQ01AE7KL No results +7196 JY8QFUQ01CNJXO productive (see comment) Homsap IGHV3-23*05 F 826 87.79 187/213 nt 86.85 185/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 7 7 10 7.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggatcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7197 JY8QFUQ01CSNHN unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 998 96.28 207/215 nt 95.81 206/215 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDNYGDYW# out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7198 JY8QFUQ01APQA8 productive Homsap IGHV4-61*02 F 884 89.14 197/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.38.11] CARDFGGSYNLVAYW in-frame + tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7199 JY8QFUQ01CLMWX productive (see comment) Homsap IGHV3-9*01 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); cctctggatTtaacctttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7200 JY8QFUQ01B2XKD productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); ctctggattctccgtcagtaAgttactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca +7201 JY8QFUQ01CWUC3 No results +7202 JY8QFUQ01BAPUZ No results +7203 JY8QFUQ01A22DL No results +7204 JY8QFUQ01AVF5E unproductive Homsap IGHV3-11*01 F 891 90.32 196/217 nt Homsap IGHJ6*01 F 93 64.71 33/51 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CTRRGFMDV# out-of-frame + ctctggattcactttcagtgactactacatgaattgggtccgccaggctccagggaagggcctggagtggctttcatacattactgcaagtggtgccatcatacactatgcagactctgtgaagggccgattcatcatctccagggacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaaggaccacggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggcaacgtggtcgtcgcatgcctggtcccagggcttcttccccc +7205 JY8QFUQ01DWOBL No results +7206 JY8QFUQ01DOXH7 unknown (see comment) Homsap IGHV3-74*03 F 162 59.83 70/117 nt 8 8 X 8.8.X [1.17.4.X] null + No rearrangement found stop codons ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtc +7207 JY8QFUQ01CLHEU productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 900 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [1.17.38.11] CNTDLGGSWYTFYSDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 59 of V-REGION: 6 nucleotides (from position 89 in the user submitted sequence), (do not cause frameshift) ctctggatacactgtcataaatgcctggatgagttgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaggtgatggtgtgacaacagaatacgctgcatccgtgaaaggcagattcaccatcacaagagatgactcaaggaacacgttgtatctacaaatgaacagcctgaaaaccgaggacacagccatatattattgcaacacagatctgggcgggagttggtacaccttctattctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +7208 JY8QFUQ01DUDRD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 980 95.35 205/215 nt 94.42 203/215 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.16.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) tctggattcacctacagcagcGtatgccatgagctggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7209 JY8QFUQ01BQERB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 8 8.8.8 [1.17.38.11] CAKRYSLDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift); ctctggattcacctttaagaactatgccttaaAactgggtccgccaggctccagggaaggggctgaagtgggtctccggaatcagtgctactggtgaaagcacacactacgcagactccgtaattggccggttcaccatctccagagacgattccaagaatacgttatatctgcaaatgaacagcctgagagccgaggacacggccgtatatttctgtgcgaaacgatattctcttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +7210 JY8QFUQ01AU3N4 No results +7211 JY8QFUQ01A7ZD8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7212 JY8QFUQ01AKSDK No results +7213 JY8QFUQ01AL0HO productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 853 89.2 190/213 nt 88.73 189/213 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 9 7 12 9.7.12 [0.16.38.11] CAANLGHGSYFKYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) ctggtgactccgtcagcagtgataactggtggagttgggtccgccagaccccaggaagggctggagtggattggagaaatctatcatggtgggaccaccaactacaatccgtccctcaagggtcgagtcaccttatcggtcgacaagtccaagaaccaattctctctgagaatgacctcttttaccgccgcagacacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7214 JY8QFUQ01AQZ7D productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 867 89.72 192/214 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [0.17.38.11] CTRDIGGRYSYW in-frame - cggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7215 JY8QFUQ01B38Y1 No results +7216 JY8QFUQ01A627H productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttttggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggcaacgtggtcgtcgcatgcctggtccagggcttccttcccccg +7217 JY8QFUQ01CWZ6T productive (see comment) Homsap IGHV3-7*01 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 7 8 6 7.8.6 [1.17.38.11] CVKSIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 23 in the user submitted sequence), (cause frameshift) cctctggattcacatttagcagttttggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagtgggatggaagtgataaaaagtatatggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactatatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtgaaaagcattgactcctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7218 JY8QFUQ01ALE0U No results +7219 JY8QFUQ01DJBL8 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 826 86.04 191/222 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARRHYGEGLFDYW in-frame - tcctttggtggctccatcaccaataataattacttctggggctggatccgccagcccccagggaaggggctggagtggattggggatgtccagtatagtgggagcacctactccagcccgtccctcaagaggcgggtcaccatgtctgtggacgtgtccaaaagtcaggtctccctgagactgagctctgtgaccgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7220 JY8QFUQ01DF9MN productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 862 89.67 191/213 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 2 8 7 11 8.7.11 [1.17.38.11] CARDRQSWGIDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggattcaccgtcagtaacaactacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggtgacacatactacgcagactccgtgaagggccgattcaccatctccagagacaacgccaagaatacactttttcttcaaatgacttccctgagagtcgaagatacggccatttattactgtgcgagagatcgtcagagctgggggattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7221 JY8QFUQ01CU7F2 productive Homsap IGHV3-30*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcaccttcaatacctattctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7222 JY8QFUQ01BLLRQ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCGNGACHVADYW in-frame + cctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +7223 JY8QFUQ01B0QFN productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7224 JY8QFUQ01ADN3R productive Homsap IGHV2-5*02 F, or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F 839 86.88 192/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 3 10 7 11 10.7.11 [1.17.38.11] CAHFGPQEHFDFW in-frame + tctctggattctcactcagcaccaatggaatgggtgtgggttggatccgccagcccccgggagaggccccagactggctcgctctcatttattgggatgatgataagcgataccggccatccctagagagtagactcaccatcaccaaggacatctccacaaaccaggtggtccttagaatgaccgacatgggccctgcagacacagccacatatttctgtgcacactttggaccacaggagcacttcgacttttggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7225 JY8QFUQ01C83PZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7226 JY8QFUQ01DB51K productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt 97.36 221/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgGagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7227 JY8QFUQ01CD61U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 874 89.04 195/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [2.17.38.11] CVREGAATGSFYYW in-frame - acctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7228 JY8QFUQ01CH9Y2 unknown (see comment) Homsap IGHV3-7*01 F 1031 96.79 211/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7229 JY8QFUQ01DLOWS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 784 84.47 185/219 nt 83.56 183/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); tgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7230 JY8QFUQ01BHEVY No results +7231 JY8QFUQ01ALCUA No results +7232 JY8QFUQ01B8NBJ unproductive (see comment) Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CARVIPGRGNYA#FDVW out-of-frame + stop codons ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgctttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7233 JY8QFUQ01C2A2E productive (see comment) Homsap IGHV3-13*01 F 904 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD4-11*01 ORF 3 8 7 17 8.7.17 [2.17.38.11] CAREVTRLTVPYYLYFDLW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 97 of V-REGION: 'G' (1 nucleotides at position 193 to 193 in the user submitted sequence), (cause frameshift); gtctctggaatcaccttcagtgactccgacatgcactgggtccgccaagctccaggagaaggtctggagtgggtcgcagctattggaactgctggtgatacatactatgcagactccgtgaagggccgattctccattaccagagagaatgccaagaactccttgtttcttcaaatgaacagcctgagagccGggggacacggctgtttattattgtgcaagagaggtgactagacttactgtcccctattacttatacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7234 JY8QFUQ01B0Z1K productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1047 99.07 212/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + ctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7235 JY8QFUQ01BJU8Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctncctggtcaaggactacttcccccgaaccggtgacggtgtgcgtggaactcag +7236 JY8QFUQ01BW8SK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaaatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +7237 JY8QFUQ01BXPG4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD1-1*01 F 1 7 8 15 7.8.15 [2.17.38.11] CAKDVTFESHFFAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) agcctctggattcaccttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaagggccgattcagcatctccagagacaacgccaagaactccctgtatctggaaatgagcagtctgagagttgaggacacggccttgtattactgtgcaaaagatgtcacatttgaaagtcacttcttcgctatggacgtctggggccaagggaccacggtcaacgtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7238 JY8QFUQ01BE71O unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 648 77.42 168/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (77,42% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactatttccccgaaccggtgacggtgtcgtggaactcag +7239 JY8QFUQ01AVODA No results +7240 JY8QFUQ01ALKSP productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-9*01 F 1 8 8 21 8.8.21 [1.17.38.11] CATARPTNARRYFAWLSQLFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'T' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); cctctggattcaatttcagtaattacaccatgaactgggtccgccagcctccagggaagaggcTtggagtgggtcgcatccattaatgttggcactacttatatatattacggagacgcagtgaagggccgattcaccatctccagagacgacgccaagaactcgttgtttctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgcgacagcccgccccacaaacgcaagacgatattttgcctggttatcgcaactctttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7241 JY8QFUQ01CGG03 No results +7242 JY8QFUQ01CB86C unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7243 JY8QFUQ01BBLQU productive Homsap IGHV3-11*01 F 954 93.55 203/217 nt Homsap IGHJ2*01 F (see comment) 211 88.68 47/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CADIRLGDWCFDIW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtgaccactacatgagttggatccgccaggctccagggaaggggctggagtggatttcatatattagtactagtggtaatatgatttattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaactcactgtatctgcagatgaacagcctgagagccgaggacacggccgtctatttctgtgccgatataagactgggtgactggtgcttcgatatctggggccggggcaccctggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7244 JY8QFUQ01CJR5I No results +7245 JY8QFUQ01A3GKV productive Homsap IGHV4-39*02 F 978 94.09 207/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 14 10.7.14 [1.17.38.11] CARRALDSSGHYIDIW in-frame + ctctggtgactccatttccagtactagttattactggggctgggtccgccagcccccagggaaggggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagacgcgcattagacagtagtggtcattacattgacatctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctgatccagggcttcttccc +7246 JY8QFUQ01BEHBE productive (see comment) Homsap IGHV3-9*01 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [2.17.37.11] CVRQAYYHDSSAYFFSRYWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 158 in the user submitted sequence), (cause frameshift) agcctctggattcactttgatggactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacgccagaagtccctgtttctgcaaattaaaagtctgagagttgaggacacggccttatattattgtgtgaggcaagcgtattaccatgatagcagtgcttacttcttctcccgctactggtacttcgatctctggggccgtggcaccccggtcactgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactactttcccgaaccggtgacggtgtcgtggaactcag +7247 JY8QFUQ01AZKGW unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F (see comment) 781 84.98 181/213 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD2-21*01 F 1 8 8 X 8.8.X [X.17.38.11] CARDNVTFWDAFDI## out-of-frame - Low V-REGION identity (84,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gggttaaccttcagtgaggatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagtcatttggaacaatggaaagacctttcactatgcagactccgtgaagggccgcttcgtcatctcccgagacaattccaagagcaccctatatttacaaatgaatagcctgagagtcgaggacacggctgtgtattactgcgcgagagataatgtcaccttttgggatgcctttgatatttggggcccgggggacaacggtcaccgtctcttcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggnccagggcttcttcccccag +7248 JY8QFUQ01AB5G0 No results +7249 JY8QFUQ01DA6Y3 productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 70 of V-REGION: 1 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctcctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7250 JY8QFUQ01BOPKJ No results +7251 JY8QFUQ01DEYUA productive Homsap IGHV3-13*01 F 903 91.59 196/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD4-11*01 ORF 3 8 7 17 8.7.17 [1.17.38.11] CAREVTRLTVPYYLYFDLW in-frame + ctctggaatcaccttcagtgactccgacatgcactgggtccgccaagctccaggagaaggtctggagtgggtcgcagctattggaactgctggtgatacatactatgcagactccgtgaagggccgattctccattaccagagagaatgccaagaactccttgtttcttcaaatgaacagcctgagagccggggacacggctgtttattattgtgcaagagaggtgactagacttactgtcccctattacttatacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7252 JY8QFUQ01AKAO6 No results +7253 JY8QFUQ01AL1GA unproductive (see comment) Homsap IGHV3-48*01 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.16.38.11] CARASTFYYDGSGYRDA#FDIW out-of-frame - stop codons in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccaggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgctttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7254 JY8QFUQ01BMK34 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 957 92.38 206/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.38.11] CTHLREEMSYEW in-frame + ctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7255 JY8QFUQ01A7QTA unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag +7256 JY8QFUQ01A60BS unknown (see comment) Homsap IGHV3-7*03 F (see comment) 460 67.58 148/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (67,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7257 JY8QFUQ01B0ROB unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 765 83.41 181/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagccccgaggacacggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7258 JY8QFUQ01CEI9Z productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 535 92.06 116/126 nt 91.27 115/126 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 X 19 8.X.19 [1.6.26.11] CANASPRITGTYFYYYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 91 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7259 JY8QFUQ01B9GV0 No results +7260 JY8QFUQ01BZGDR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDTITMGGDVAPLFDYW in-frame + ctctggattcacctttagtaactatgacatgggctgggtccgccaggctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +7261 JY8QFUQ01BCV2O productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 939 93.46 200/214 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD4-17*01 F 2 8 7 18 8.7.18 [1.17.38.11] CASVVTINDNGDYTWAFDVW in-frame + ctatggtgggtccttcaataattacttctggacctggatccgccagtccccagggaaggggccggagtggattggggaaatcaatcatagtggtagcaccaactacaatccgtccctcaagagtcgagtcaccatctcaatagacacgtccaagatccagttctccctgcagctgagctctgtgaccgccgcggacacggctgtctattactgtgccagtgtagtgaccattaatgacaacggtgactacacgtgggcttttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +7262 JY8QFUQ01A5JF4 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7263 JY8QFUQ01CO5KN productive Homsap IGHV3-30*07 F, or Homsap IGHV3-30*09 F or Homsap IGHV3-30*12 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*04 F (see comment) 315 77.06 84/109 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 X X 13 X.X.13 [X.X.36.11] CARGGGGKSIPLDNW in-frame + Low V-REGION identity (77,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggcttcacgttcagtagttatggcatctccagagacaattccaagaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatgtaccattgtgcgagaggcggcggtggtaagtccattccacttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7264 JY8QFUQ01CDC70 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.16.38.11] CVRPDNYFGSGSAWMDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaaggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7265 JY8QFUQ01BC4RR No results +7266 JY8QFUQ01BHL2L No results +7267 JY8QFUQ01DTYCY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7268 JY8QFUQ01ASNTD No results +7269 JY8QFUQ01B3YMQ unknown (see comment) Homsap IGHV3-23*05 F 116 54.14 72/133 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcacctttagcaactatgccatgagctgggtccgccaggctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7270 JY8QFUQ01CNKFF productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + tctggattcaccttcagtatccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7271 JY8QFUQ01ALFQX productive Homsap IGHV4-61*03 F 152 66.25 53/80 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 1 X X 13 X.X.13 [X.X.26.11] CATVRHLGERIFDFW in-frame - tctctggggccaccatgagtagtttctactggagctggctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7272 JY8QFUQ01BH8BR productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 805 86.11 186/216 nt 85.19 184/216 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 7 17 8.7.17 [1.16.38.11] CARDSGSSEYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) ctctgggattcagcttaagttcttatggcatgaactggtccgccaggctccatggggggggctggagtgggtctcattcattaacagtattagtagtataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7273 JY8QFUQ01BWDQ9 productive Homsap IGHV1-8*01 F 840 87.85 188/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARVGGTHYHYGVDVW in-frame - cggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagatctgacgacacggccgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7274 JY8QFUQ01CLN2W productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7275 JY8QFUQ01BRKIN No results +7276 JY8QFUQ01DRFXI productive (see comment) Homsap IGHV4-61*02 F 874 89.04 195/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 114 in the user submitted sequence), (cause frameshift) ctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7277 JY8QFUQ01BV6MY No results +7278 JY8QFUQ01AKC4T productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7279 JY8QFUQ01CDXQM unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7280 JY8QFUQ01AJ9G4 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7281 JY8QFUQ01AQN6R No results +7282 JY8QFUQ01BP92X productive Homsap IGHV3-7*01 F 882 89.4 194/217 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7283 JY8QFUQ01BGZXV productive (see comment) Homsap IGHV3-7*01 F 939 93.46 200/214 nt 92.52 198/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [0.17.38.11] CATSPSDFDRRWGYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 77 of V-REGION: 'A' (1 nucleotides at position 133 to 133 in the user submitted sequence), (cause frameshift); tggatttagctttagaaccttttggatgagctgggtccgccaggctccagggagggggctggagtgggtggccaacatAaaagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaAccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggtgccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7284 JY8QFUQ01C847F productive (see comment) Homsap IGHV3-11*01 F 984 95.79 205/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD1-1*01 F 3 8 8 13 8.8.13 [1.17.37.11] CARVNTWNADYFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 3 nucleotides (from position 104 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcagtgactactacatgatctggatccgccaggctccagggaaggggctggagtgggtttcatacattactagtcgtggtactatcatgtacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggccatttattactgtgcgagagtgaacacatggaacgccgactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7285 JY8QFUQ01CXFYZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7286 JY8QFUQ01BWKDJ unproductive (see comment) Homsap IGHV3-9*01 F 1026 97.24 211/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-20*01 F 3 8 8 X 8.8.X [1.17.38.11] CAK*YGVYLE#YIDHW out-of-frame + stop codons ctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattacttggaacagtggtaggataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattattgtgcaaaatgatatggggtatacctggaagtacattgaccactggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag +7287 JY8QFUQ01A0GI6 productive (see comment) Homsap IGHV4-61*02 F 906 90.45 199/220 nt 89.55 197/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.16.38.11] CAREHSRTMGGARELDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) tctctggtggccccatcagcagtggtacttactactggacttggatGccggcaggccgccgggagggactggagtggatcggacgtgtttatattagtgggagcaccacctacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgccgctgacacggccgtatattactgtgcgagagaacatagtaggacgatgggcggggcgagagagcttgactcctggggcctgggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7288 JY8QFUQ01BBJ9Z productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 692 80.47 173/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame - Low V-REGION identity (80,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7289 JY8QFUQ01A7PO5 unknown (see comment) Homsap IGHV3-74*03 F 115 54.2 71/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ttctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +7290 JY8QFUQ01A07AL No results +7291 JY8QFUQ01AQOTE No results +7292 JY8QFUQ01CWG6U No results +7293 JY8QFUQ01CFCLX No results +7294 JY8QFUQ01DJGQJ unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt 86.7 189/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD3-9*01 F 3 7 8 X 7.8.X [2.16.38.11] CASLNTHAGPGAERSAFDI## out-of-frame - in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 26 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) gccctctggattcaccttcagtaacacagaatgaattgggtccgtcagctccagggaaggggctcgaatgggtctcgtccattaccagttccagtagttacatatactacgcagactcggtgacgggccgattcaccatctccagagacaacgccaaggggtcactctatctgcacatgagctaccttagagccgaggacacggctgtctattactgtgcgagcctaaacacgcacgcgggaccgggagccgaaaggtctgcttttgatatctgggggccaagggacaatggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7295 JY8QFUQ01A5XYT productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7296 JY8QFUQ01C5XRQ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactc +7297 JY8QFUQ01BG1NI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctagtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7298 JY8QFUQ01ALKNG productive Homsap IGHV3-7*01 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 2 8 8 18 8.8.18 [0.17.38.11] CSRHGGYTKLYNQNVYLDYW in-frame - ctggattcacatttagcaacttttggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaaaataaacccagtcggaagtgagaaatactatgtggactctgtgaagggccgattcaccacctccagagacaactctagaaactcgctgtgtctgcaaatggacagcctgagagccgaggacacggctgtgtattactgttcgagacatggaggttacacgaaactctacaatcaaaatgtctaccttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7299 JY8QFUQ01CGEFL No results +7300 JY8QFUQ01CI7BL productive (see comment) Homsap IGHV2-5*01 F 1054 92.28 227/246 nt 91.87 226/246 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD3-10*01 F 3 10 7 14 10.7.14 [10.17.38.11] CVHGIMIRGNYNFDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'CG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); cagaccctcacgctgacctgcaccatttctgggttctcactcaacactgatgcagtgggtgtCGggggtggatccgtcagcccccaggaaaggccctggagtggcttgccctcaattattggaataatgataagcgctatagcccatctctgaggagtaggctcaccatcaccaaggacacttccaaaaaccaagtagtcctcacaatgaccaacatggaccctgtggacacagccacgtattattgtgtacacggtattatgattcggggaaattacaactttgactattggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7301 JY8QFUQ01AE5NB No results +7302 JY8QFUQ01A38QG No results +7303 JY8QFUQ01AXWK7 No results +7304 JY8QFUQ01CMKMT productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7305 JY8QFUQ01BEOIK productive Homsap IGHV3-11*01 F (see comment) 740 83.49 177/212 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 2 7 8 15 7.8.15 [X.17.38.11] CARVRCSGNTCGAFDLW in-frame - Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gattcagcttaagtgactactacatgacctgggtccgccaggccccagggaagggactggagtggctcgcctacattagtcgaactgatgattccgtatattccgcagagtctgtggtgggccgattcaccgtctccagggacaacgtccaaaactcactgtttttgcagatgattggcctgagagacgaggacacggccgtatattactgtgcgagagtccgctgtagtggtaatacctgcggggcttttgatttgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7306 JY8QFUQ01CYKKW No results +7307 JY8QFUQ01C8HIY unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 778 84.72 183/216 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [2.17.38.11] CARERGSGPP#GMDVW out-of-frame - Low V-REGION identity (84,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ggttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaagaggttcgggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7308 JY8QFUQ01DDY85 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7309 JY8QFUQ01CABSD unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 867 87.44 195/223 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD1-14*01 ORF 1 8 10 X 8.10.X [1.17.38.11] CTADVPSPLAQNDF# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcactttcaatggcgcctggatgaactgggtccgccaggctccagggaagggtctggagtgggttgcccgtataaaaacttttggtgaaggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcaaaaaaagggctgtatctgcagatggacagcctgagaatcgaggacacagccaagtattactgcaccgcagatgtcccgtcaccattagcgcaaaatgacttctgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7310 JY8QFUQ01DHRCK No results +7311 JY8QFUQ01CYA9E productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1075 100.0 216/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7312 JY8QFUQ01CUN1J No results +7313 JY8QFUQ01CY6MC productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARPLRATYGDYVNW in-frame + ctctggattcaccttcgataactatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcaaaggatggaagtattgaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacaatttatctgcaaatgaacattgtgagggttgaggacacggctatgtattactgtgcgagaccccttcgggcaacttacggtgactacgtgaactggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +7314 JY8QFUQ01A6JDD unknown (see comment) Homsap IGHV3-47*01 P, or Homsap IGHV3-7*01 F or Homsap IGHV3-7*03 F 148 57.6 72/125 nt 8 6 X 8.6.X [1.17.9.X] null + No rearrangement found cctctggattcagcttcaatagttatactttgagttgggtccgccaggctccagggaaggggctgcagcacccagccagatggggacgtggtcatcgcctgcctggtccagggcttcttccccca +7315 JY8QFUQ01CIOPG productive (see comment) Homsap IGHV4-39*02 F 862 87.84 195/222 nt 87.39 194/222 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 2 10 7 17 10.7.17 [2.17.38.11] CARQMGYSGSGLSVWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); gtctctggaggctccatcaacactaatcgttactactgggtctggtttcgccagAcccccggggaaggggctggagtggattgggactatttattatactgggatcaccaactacaatccattcttcaagagtcgagtcaccatgtccgtagacacgtccagccaccacttctccctgaggttgagctctgtgaccgccgtagacacggctgtctactactgtgcgagacaaatgggatactctggttcggggctcagtgtgtggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7316 JY8QFUQ01BNQF3 productive Homsap IGHV3-30*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [1.17.38.11] CVKNDLSWGTIEHYFDYW in-frame + cctctggattcacgttcaacatttatggtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7317 JY8QFUQ01B5FXA No results +7318 JY8QFUQ01CIV81 productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7319 JY8QFUQ01A1MW1 unknown (see comment) Homsap IGHV3-7*01 F 981 94.47 205/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga +7320 JY8QFUQ01A45PJ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 928 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 79 to 81 in the user submitted sequence), (do not cause frameshift); gcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7321 JY8QFUQ01BHUNQ No results +7322 JY8QFUQ01DBFW5 No results +7323 JY8QFUQ01A2XWB productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 750 83.64 179/214 nt 83.18 178/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7324 JY8QFUQ01BJCGQ productive (see comment) Homsap IGHV3-30*01 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD5-12*01 F 3 8 8 12 8.8.12 [1.17.37.11] CARDFDTDDVGTYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 214 in the user submitted sequence), (cause frameshift) tctctggattcatcttcgatagttatgctctgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttgtttcatatgatggaaaatataagcaatatgcagattctgtggagggccgattcaccatctccagagacaactccaagaacacaggatatctgcaaatgaacagcctgacatctgacgatacggctgtgtattttgtgcgagagacttcgatactgacgacgtgggcacctactggggccggggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7325 JY8QFUQ01CYR3J productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggcgccctgaccagcggcgtgca +7326 JY8QFUQ01A27H2 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccagttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7327 JY8QFUQ01CQQVZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7328 JY8QFUQ01BS83C productive Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7329 JY8QFUQ01AKSZ0 No results +7330 JY8QFUQ01C7RKZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca +7331 JY8QFUQ01BDK0T productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +7332 JY8QFUQ01BNJGF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7333 JY8QFUQ01ASTYN productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 750 83.64 179/214 nt 83.18 178/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.16.38.11] CARGTRYNNGLDAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift) tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactgagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7334 JY8QFUQ01CG6JV productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame + tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +7335 JY8QFUQ01CPCC5 No results +7336 JY8QFUQ01CB4MT productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7337 JY8QFUQ01BQT9J productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-48*04 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + ctctggattcagcttcagagactatggcatggcctgggtccgccaggctccagggaaggggctggagtgggtctcatacattggtaggattattagtgacatatactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7338 JY8QFUQ01ACO6B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagcagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7339 JY8QFUQ01B3G3T productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 11 8.8.11 [1.17.37.11] CNLHPYGDSSDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 160 in the user submitted sequence), (cause frameshift) ctctggactcaccttcagtcgcctctggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtatagatagtgatgggaataacataatctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaaacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtaaccttcatccctacggtgactcctccgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7340 JY8QFUQ01C9I3O productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7341 JY8QFUQ01AO5SQ unknown (see comment) Homsap IGHV3-64*02 F, or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 138 56.06 74/132 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons tctggattcaccttcagtgactatgccatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7342 JY8QFUQ01A47U3 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1045 97.72 214/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [2.17.38.11] CARPYCGGDCHNRGAFDIW in-frame - gcgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7343 JY8QFUQ01BR1YM productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CATSPSVGSTTVGYW in-frame + ctctggattcacctttagaaactattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgacagatggaggtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgccacatcccctagcgtgggatctacgacggtgggctactggggccggggaaccctggtaaccggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +7344 JY8QFUQ01CIQBS productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 748 82.65 181/219 nt 82.19 180/219 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [2.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttctccca +7345 JY8QFUQ01B5GNU productive (see comment) Homsap IGHV3-48*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGNYYYFGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); cctctggatTtcctcttcagtagctttaacatgaactgggtccgccaggttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccatctactactgtgcgagacaaactgggaattattattacttcggtatggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7346 JY8QFUQ01BMVQV productive (see comment) Homsap IGHV4-61*01 F 983 94.12 208/221 nt 93.21 206/221 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [2.16.38.11] CARGGSGGAYWNLIRDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 67 of V-REGION: 'TATAATCCCCTG' (12 nucleotides at position 111 to 122 in the user submitted sequence), (do not cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) gtctctggtggctccgtcagcagagatatttactactggagctggatccggcagcccccagggaaggactggagtggattgggtatatgtatcacagagggaacactaagTATAATCCCCTGtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtgggtccggtggggcctactggaatttgatccgggactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7347 JY8QFUQ01AZ07T productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactc +7348 JY8QFUQ01APEOL unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7349 JY8QFUQ01CHJQ8 No results +7350 JY8QFUQ01BW6QX productive Homsap IGHV3-9*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + ctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7351 JY8QFUQ01DABFP productive (see comment) Homsap IGHV4-39*02 F 983 94.12 208/221 nt 93.21 206/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [2.16.38.11] CARIVVRQFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gtctctggtgactccatttccagtactagttattactggggctgggtccgccagccccagggaaggggctggagtggaTttgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7352 JY8QFUQ01DR0WN productive (see comment) Homsap IGHV3-7*01 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); cctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca +7353 JY8QFUQ01AZ2P8 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7354 JY8QFUQ01CWGWW unknown (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F 103 57.3 51/89 nt 8 4 X 8.4.X [0.17.X.X] null - No rearrangement found ctggatttacctttagcagttatgccatgaactgggtccgccagatggaaacgtggtcatcgcctgcctggtccagggcttcttcccca +7355 JY8QFUQ01A5WBI productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7356 JY8QFUQ01BIL7K No results +7357 JY8QFUQ01A8CYP No results +7358 JY8QFUQ01A8MTS No results +7359 JY8QFUQ01AXEG5 No results +7360 JY8QFUQ01A5OJ5 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7361 JY8QFUQ01CAVYT unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggcccagggaaacctggtcaccgtctctcagcctccaccaagggcccatcggtcttcccctggcacctcctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7362 JY8QFUQ01BEP9A productive Homsap IGHV3-48*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDQSPGVAVAGPDYW in-frame - ctctggattcaccttcagtagatatagtatgaactgggtccgccaggctccagaaaaggggctggagtgggttgcatacattagaagtagcagtagtgtcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcaaagtccgggtgtagcagtggctggtcctgattactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7363 JY8QFUQ01A3QEB productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVKGAGTTVNWFDIW in-frame + ctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7364 JY8QFUQ01AFME4 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 469 82.48 113/137 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (82,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc +7365 JY8QFUQ01BGBMV unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 896 90.37 197/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + cctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +7366 JY8QFUQ01A7HQ8 productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaact +7367 JY8QFUQ01BTRU2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggcgtcgtggaactc +7368 JY8QFUQ01C7540 productive Homsap IGHV3-30*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [1.17.38.11] CVKNDLSWGTIEHYFDYW in-frame - ctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7369 JY8QFUQ01BJNO1 No results +7370 JY8QFUQ01AD1LR unproductive (see comment) Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7371 JY8QFUQ01ATFLQ No results +7372 JY8QFUQ01A5ZNA productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 849 90.73 186/205 nt 89.76 184/205 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 9 nucleotides (from position 14 in the user submitted sequence), (do not cause frameshift) ctctggtgactctcacttctggagctggatccggcagcccccagggaagggcccggagtggattggttatgtctataacagtgGggaccaccaactacaacccctccctcaggagtcgagtcaccatttctatcgacacgtccaagaagcagatctccctgaagttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7373 JY8QFUQ01BS9AI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKENYFESSGYHGMNVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcacctttaccaactatgccatgacctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtaatcgtggtactggagtgtactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagagccgaggacacggccctttattactgtgcgaaagagaattactttgagagtagtggttatcacggtatgaacgtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7374 JY8QFUQ01DM0N2 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 800 86.05 185/215 nt 85.12 183/215 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.16.38.11] CARDTGSSKFARYDGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 42 in the user submitted sequence), (cause frameshift) tctggattGcagcctcagtacctctggcttgaactgggtccgcaggccccagggaagggactggagtggatctcattcatcaatagtgatggtgattacatctactacgcggagtcggtgaggggccgattcaccatctccagagacaacgccgagaagtcactgtacctgcaactgaacaacctgagagtcgaggacacggctgtgtacttctgtgcgagagataccggctcgtccaagttcgctaggtacgacggtatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7375 JY8QFUQ01A8Y0H productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAYFSTGYW in-frame - ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7376 JY8QFUQ01CJDL1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [1.17.38.11] CVRYDYSRLHRSNYFGPW in-frame + ctctggattcaccttcatcagttatggcatgagttgggtccgccagtttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7377 JY8QFUQ01BZ1XN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD2-15*01 F 2 8 8 21 8.8.21 [1.17.38.11] CAKTGGQCSGGNCYLHYYGMDVW in-frame + cctctaaattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcacaggtattagtggtggtggtgaaaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagagcatgttgtatctgcaaatgaacagcctgagagccgaagacacggccgtattttactgtgcgaaaactggcggtcaatgcagtggtggtaactgctatttgcactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +7378 JY8QFUQ01B3WVJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + tctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7379 JY8QFUQ01BFAIH productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7380 JY8QFUQ01CS7MX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7381 JY8QFUQ01ALST3 No results +7382 JY8QFUQ01DLI3D productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 9 7 12 9.7.12 [1.16.38.11] CAANLGHGSYFKYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) tctctggtgactccgtcagcagtgataactggtggagttgggtccgccagaccccagggaagggctggagtggattggagaaatctatcatggtgggaccaccaactacaatccgtccctcaagggtcgagtcaccttatcggtcgacaagtccaagaaccaattctctctgagaatgacctcttttaccgccgcagacacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7383 JY8QFUQ01A4ORW productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7384 JY8QFUQ01C5TJ1 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARDNARSYYSGVPDFW in-frame - gcgtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7385 JY8QFUQ01BL0SP No results +7386 JY8QFUQ01DFWE1 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 482 68.81 150/218 nt 68.35 149/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.16.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (68,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gcctctggattcacctttcgcagctatgccatgagctgggtccgccaggctccaggaaggggctagagtgggtctcatctatcagtggtagtggtgataaaacaaagtacgcagactccgtgaagggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7387 JY8QFUQ01A5VNA productive (see comment) Homsap IGHV4-59*03 F 931 92.59 200/216 nt 91.2 197/216 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [2.17.38.11] CARGHFDSSGYSNPLDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'GC' (2 nucleotides at position 49 to 50 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'GA' (2 nucleotides at position 65 to 66 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 95 to 100 in the user submitted sequence), (do not cause frameshift); gtctctggtgtctccatcagtagtttctactggagttggatgaggcagGCcccccagggaggggGAcctggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccctcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7388 JY8QFUQ01C90SW productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcgggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7389 JY8QFUQ01DSC06 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggGggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtggggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccagg +7390 JY8QFUQ01AWB4I productive (see comment) Homsap IGHV4-4*07 F 844 88.32 189/214 nt 87.38 187/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 7 9 8.7.9 [1.17.37.11] CARDSGDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 206 in the user submitted sequence), (cause frameshift) tctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtcCaaaaccagtgggaccccccactacaacccttccctnaagagtcgagtcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccattttttctgtgcgagagactccggggactttgactactggggcccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7391 JY8QFUQ01BNKPL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +7392 JY8QFUQ01C6ROW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKLGVAATTWNFFDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7393 JY8QFUQ01DIP2F unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 823 86.57 187/216 nt 85.65 185/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.16.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccCttcaggaactattggatgcactgggtccgccaagctccagggaagggctggagtgggtctcacgtatcaatggcgacggaagtagcacaagctacgcggactccgtgaagggccgattcaccatctccagagacaacgccgagaacacgctgtatctgcaaatgaacagtctgagagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7394 JY8QFUQ01AVC46 productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcag +7395 JY8QFUQ01B7ZEV No results +7396 JY8QFUQ01BYSCW No results +7397 JY8QFUQ01CEODQ productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctatgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7398 JY8QFUQ01BL30A productive (see comment) Homsap IGHV4-61*01 F (see comment) 781 83.78 186/222 nt 83.33 185/222 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [2.17.38.11] CARDGNRGYYSFETW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift); gtgtctggtggctccgtcagcagtggaaattcctactggacctTggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7399 JY8QFUQ01A1TPB productive Homsap IGHV4-39*03 F 924 91.32 200/219 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + ctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7400 JY8QFUQ01DL8E9 No results +7401 JY8QFUQ01ARLMX productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 2 8 7 17 8.7.17 [1.17.38.11] CAKNLRLGHSYFYNALDVW in-frame + tctctggtggcctcatcagtaattactattggacctggatccggcagcccccaggaaagggactggagtggattgggaacatctattacagtgggagcgccacctacaacccctccctcaagagtcgagtcaccatatcaatagactcgtccaagaaccagttctccctgaggctgaccgctgtgaccgctgcggacacggccgtgtattactgtgcgaaaaacttacgattgggtcacagttacttctacaacgctttggacgtatggggccaagggaccacggtcaccgtcgcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7402 JY8QFUQ01C8III productive Homsap IGHV3-30*01 F 995 95.41 208/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD1-1*01 F 1 8 8 18 8.8.18 [1.17.38.11] CAREPGRGYTPAMNWYFDLW in-frame + cctctggattcaccttcagtagccatgctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgggggttatatcatctgatggaagtaatgaatactatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacactgtatctgcagatgaacagcccgagagctgaggacacggctgtgtattactgtgcgagagagcctgggaggggttatacacctgcaatgaactggtacttcgatctctggggccgcggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +7403 JY8QFUQ01AZ4D4 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcgcctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcca +7404 JY8QFUQ01AYJT7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtgcgtggaactcag +7405 JY8QFUQ01CBSRV productive (see comment) Homsap IGHV3-64*02 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); cctctggattcaAttttcagtacttatcctatgcactgggtccgccaCggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7406 JY8QFUQ01BIOGX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 848 87.33 193/221 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.17.38.11] CARDSASSGYARYDAMDVW in-frame - cagcctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaatgggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7407 JY8QFUQ01BO9AE No results +7408 JY8QFUQ01A7RV9 productive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 7 8 14 7.8.14 [1.17.38.11] CARVRGYYGGQYFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) cctctggattcaccttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7409 JY8QFUQ01AW0QG productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame + ctctggatttaccttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7410 JY8QFUQ01AIXDP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - agcctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7411 JY8QFUQ01DLITS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7412 JY8QFUQ01BFSZY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame - cctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7413 JY8QFUQ01C28FC unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1038 96.41 215/223 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 X 8.10.X [1.17.38.11] CTRDNPPLRSLEWL#FDSW out-of-frame + stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ttctggattcacctttggtgattatagtatgagttggttccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcaaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttacctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +7414 JY8QFUQ01AC8SF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 91.71 199/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'AC' (2 nucleotides at position 115 to 116 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagttactcctggatgcactTgggtccgccaagttccaggaaaggggccggtgtgggtGctcacgaAattcaaagtgatgggagtaccccaagttacgcACggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7415 JY8QFUQ01BST27 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + tctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaact +7416 JY8QFUQ01C3ZS5 No results +7417 JY8QFUQ01BMI4Y unknown (see comment) Homsap IGHV3-72*01 F 921 90.58 202/223 nt 8 10 X 8.10.X [1.17.38.X] null + No rearrangement found ctctggtttccccttcagtgaccacttcatggactgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctggggccaaggggtacaacggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +7418 JY8QFUQ01CWGS6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame + cctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccgaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtccatcgcctgccctggtccagggcttcttcccc +7419 JY8QFUQ01BTNVR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 7 8 11 7.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift) ctctggatcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7420 JY8QFUQ01AONIM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7421 JY8QFUQ01ACRCA No results +7422 JY8QFUQ01CF15N No results +7423 JY8QFUQ01CXAVM No results +7424 JY8QFUQ01B0TRD productive Homsap IGHV3-7*01 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [0.17.38.11] CAKGGGNGDLDYW in-frame - tggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7425 JY8QFUQ01DXGGW No results +7426 JY8QFUQ01C0Y8B unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagcccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +7427 JY8QFUQ01CKUIL No results +7428 JY8QFUQ01AG17N productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 926 92.56 199/215 nt 91.63 197/215 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ccggattcagtttcagtacttaGtaacatgaattgggtccgccaggctccagggaaTggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcagccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7429 JY8QFUQ01C79VR No results +7430 JY8QFUQ01DIG69 No results +7431 JY8QFUQ01A6LUO unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagttctcacactatgaactgggtccggcaggctccagggaaggggccggagtgggtctcaaccattggtactagaggtagatccatatactacgcggactcagtgaagggccgattcaccacctccagagacaacgccaagaaatcactttatctggatatgcacagcctgagagccgaggacacggctatctattactgtgcgagagatggcagtgcacactcgtcgatctatcattactattacggcatggacgtctggggccaaggaccacggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +7432 JY8QFUQ01DBDPM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 956 92.76 205/221 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - cagcctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7433 JY8QFUQ01CGYN6 productive Homsap IGHV3-72*01 F 930 91.03 203/223 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-3*01 F 2 8 10 14 8.10.14 [1.17.38.11] CLRGFSSHYRGGMDVW in-frame + ctctggactcacgttcagtgaccactacatggactgggtccgccagactccagggaggggactggagtgggttggccgtattagagacaaagctcgcaggtacaccacagaatacgccgcgtctgtgaaaggcagattcaccattttaggagatgatttaaagaattcactgtatctacaaatgaacaacctgagaaccgacgactcggccgtgtattactgtctcagaggattttcgagccattatcggggcggtatggacgtctggggccaagggaccacggtcaccgtgtccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7434 JY8QFUQ01DWWST unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CAKEGPTLLTRPPSQL# out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaacttttggtggtagtggtggttctacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctatatcttcaaatgagcagcctgagagccgaggacacggccatatacttctgtgcgaaagaaggacctacgcttctaactcgccccccatctcaactggggtccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7435 JY8QFUQ01AOY3W productive (see comment) Homsap IGHV3-48*03 F 858 89.25 191/214 nt 87.85 188/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 7 8 13 7.8.13 [1.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 28 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 2 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagttcttatgcatgaactggtccgcctgtccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7436 JY8QFUQ01C6CR5 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 92 52.31 68/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +7437 JY8QFUQ01ACS2Y productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggGggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7438 JY8QFUQ01DBA0T productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AGCCCCA' (7 nucleotides at position 81 to 87 in the user submitted sequence), (cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcaAGCCCCAaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7439 JY8QFUQ01CJLXK productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDPSGSGWAFESW in-frame + gtctggattccctttcagtagagatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatggtatggtatgatggaagtaatacacaccatgcagattccgtgaagggccgattcatcatttccagagacaattccaagaataaagtgtatctgcaaatgaacagtctgagagacgaggacacggctgtctattattgtgcgagagatccgagcggcagtggctgggcctttgagtcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7440 JY8QFUQ01BSOXE productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +7441 JY8QFUQ01CKN05 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame + tctctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7442 JY8QFUQ01AVUA3 unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*04 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*03 F or Homsap IGHV3-66*04 F (see comment) 264 72.38 76/105 nt 8 7 X 8.7.X [1.17.1.X] null - No rearrangement found Low V-REGION identity (72,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggcttcaccgtcaataacaactacatgggctgggtccgccaggctccagggaaggggctggagtgggtcatcgcctgcctggtccagggcttcttccccca +7443 JY8QFUQ01AAWVK productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*03 F (see comment) 78 62.5 30/48 nt Homsap IGHD3-16*02 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccaggggaacccctggtcaccgtctcctcagcatcccccgaccagcccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7444 JY8QFUQ01AOPX0 No results +7445 JY8QFUQ01AH2Q8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ3*02 F 250 100.0 50/50 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKRLEGVADDAFDIW in-frame + ctctggattcacctttagcagctatgccatgggctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtgggagtggtcggagcacatactacgcagactccgtgaagggccggtacaccatctccagagacaattccaagaatacgatgtctgtgcaaatgagcagcctgagagtcgaggacacggccatatattattgtgtgaaaaggttggaaggagtggctgatgatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7446 JY8QFUQ01ADH3O productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7447 JY8QFUQ01BPLSQ productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); tttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7448 JY8QFUQ01BR0ES productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 909 91.24 198/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcatcttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7449 JY8QFUQ01ALI8J productive (see comment) Homsap IGHV3-64*02 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 7 8 10 7.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) tctggattcatttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7450 JY8QFUQ01BX8NY productive Homsap IGHV3-66*02 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 12 8.7.12 [2.17.38.11] CARQTAPFGYFEDW in-frame - acctcggaattctccgtcagtgacagtcacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtagtgcatattatgcagactccgtgaggggccgattcaccatcgccagagacaaatctaagaacgtgttgtatcttcaaatgaacagtctgagacctgaggacacggctgtgtactactgtgcgagacagactgccccttttgggtactttgaggactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7451 JY8QFUQ01DML2W unproductive Homsap IGHV1-8*01 F 993 96.26 206/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [0.17.38.11] CARDPNSGG#YW out-of-frame - tggatacaccttcagcaattatgacatcaactgggtgcgacaggccactggacaagggcttgagtggatgggacggatgaaccctgacagtggaaacacagactatgcacagaggttccagggcagagtcaccatgaccaggaacacctccataagcacagcctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgcgagagatccgaattcgggggggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgttgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7452 JY8QFUQ01DN37C productive (see comment) Homsap IGHV3-48*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARDMIIFGGALDNW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); gcctctggattcgccttcagtagttccagcatgaactgggtccgccagggtccagggaaggggctggagtggatttcacacattaGggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggagcccttgacaactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7453 JY8QFUQ01CJ7C5 productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 92.83 207/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift); ctctgcagcctctggattcattgtcaatagcaactacatgGagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7454 JY8QFUQ01BBIUK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7455 JY8QFUQ01C2RJ9 No results +7456 JY8QFUQ01A7YQM No results +7457 JY8QFUQ01BR9AM unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 448 70.1 136/194 nt 8 7 X 8.7.X [1.17.31.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BR9AM ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (70,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7458 JY8QFUQ01DHYKY productive Homsap IGHV2-5*02 F 954 88.11 215/244 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 10 7 11 10.7.11 [9.17.38.11] CVRMDVDTAVDFW in-frame - gaccctcacactgacctgcacctgctctggattctcactcaccgataacggagtgggtgtgggctggatccgtcagcccccaggacaggccctgcagtggcttgcactcgtttattgggatgatgatatgcgccacaactcatctctgaggaacagagtcatcatcgccagggacacctccaagaaccaggtggtcctaacattggccaacatgggccttgtggacacagccacatatttctgtgtgcgcatggacgtggatacggctgtagatttctggggccagggaatcctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7459 JY8QFUQ01DBRNA unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7460 JY8QFUQ01CGU5O productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 21 8.8.21 [0.16.38.11] CARGWLTAADTGVASGHDWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tggatacaccttcaccagctactatatgcactggatacgacaggcccctggacaaggcttgagtggatgggaataatcaaccctagtggtggtaccacaaggtacgcacagaagttccagggcagagtcttcatgaccagagacacgtccacgagcacagtccacatggaggtgaacggcgtaagatctgacgacacggccgtgtattactgtgcccgagggtggctgacagcagctgataccggggtggcgtcagggcacgattggttcgactcctggggccagggaaccctggtaaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7461 JY8QFUQ01C4E92 unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*04 F (see comment) 314 60.47 130/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (60,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctatggtgggtcactcagttcttatttctggagctggatccgccagtccccagagaaaggactggagtggattggggaaatcaatcagagtggaaccaccaactacaacccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7462 JY8QFUQ01CNGTA productive Homsap IGHV3-11*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7463 JY8QFUQ01BFMTU No results +7464 JY8QFUQ01CHR3O productive Homsap IGHV3-11*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKDRGKSGSYGLDHW in-frame + ctctgggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccagggtcaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgaaagatcgggggaaaagtgggagctacggacttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7465 JY8QFUQ01CBVG3 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARYGSGSQKYLDSW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctggtggctccctcaataattactactggagttgggtccggcagcCccccagggaagggactggagtggattgggtggatctattacaatgggatcaccgcctacaacccctccctcaagagtcgactcaccatatcagtggacacgtccacgaaccagttctccctgaggctgttctctgtgaccgctgcggacacggccgtgtattattgtgcgagatatggtagtggttcccaaaaatacttggactcttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7466 JY8QFUQ01DCPQS unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGS## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'T' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); caggattcaccttcagtaggtactggatgcactgggtccgccaagttccaTgggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7467 JY8QFUQ01CAM1Y unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ1*01 F, or Homsap IGHJ5*02 F (see comment) 110 69.39 34/49 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDNYGDY# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcacgtttggttcgtattggatgagttgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactgggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7468 JY8QFUQ01A9X74 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 447 93.14 95/102 nt 8 7 X 8.7.X [1.17.X.X] null - No rearrangement found cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgaca +7469 JY8QFUQ01BCZ3W productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame - Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7470 JY8QFUQ01B5689 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca +7471 JY8QFUQ01B5XLS productive (see comment) Homsap IGHV3-30*07 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDFFIGGYYGMDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); ctctggattctccttcagaagttaCtcttttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7472 JY8QFUQ01C3D8T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccaatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttctccgaaccggtgacggtgtgcgtggaactcag +7473 JY8QFUQ01A9WLN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7474 JY8QFUQ01DBVGM unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGVVTA#LDYW out-of-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +7475 JY8QFUQ01BOT3U unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 112 53.73 72/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7476 JY8QFUQ01CRR36 No results +7477 JY8QFUQ01ANP89 productive Homsap IGHV3-48*02 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARAGGNCYDAGECWFDPW in-frame + ctctgggttcgccctcagttcctatagcatgaactggctccgccaggctccagggaagggactggagtggatttcatacattagtagtactagtgttgtcatacgctatgcagactctgtacaaggccgattcaccatctccagagacaatgccaagaactcactgtttctgcaaatgaatagtctgagagacgaggacacggctgtttattactgtgcgagagccggtggtaactgctatgacgccggtgaatgctggttcgacccctggggccagggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7478 JY8QFUQ01A1L2W productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CAKDRDPGYCLSNSCVDGLAFDSW in-frame + ctctggattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctccggtattagtggtagtggtggtaacacatacttcgcagactccgtgaagggccggttcaccatctccagagacaattccaggaacacgctgtttctacagctgaacagcctgagagccgccgacacggccgtatattactgtgcgaaggatcgtgacccgggatattgtcttagtaatagctgtgttgacggcctagcctttgactcctggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +7479 JY8QFUQ01CLY2T unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.17 200/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGYHGPFDS## out-of-frame + ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacacatactactcagactccgtgaggggccggttcaccatctccagagacaacgccaagaacacgatgtatctgcaaatgaacaccctgagagacgaggacacggccgtctatttctgcgcgaaaggttaccacggcccctttgactcttggggccggggcaaccctggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7480 JY8QFUQ01CHZU0 unproductive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1110 100.0 223/223 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFLDY## out-of-frame + ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttactttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7481 JY8QFUQ01A2Y02 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 821 85.97 190/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARQLSGDYASFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatgagttttccctgacactgacctctatgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +7482 JY8QFUQ01CLNEV No results +7483 JY8QFUQ01DNPTN No results +7484 JY8QFUQ01DOWDA unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7485 JY8QFUQ01CZONR productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 927 92.17 200/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) gtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7486 JY8QFUQ01BS3N8 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 514 92.44 110/119 nt 8 8 X 8.8.X [1.17.5.X] null - No rearrangement found cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagaccca +7487 JY8QFUQ01CITVF No results +7488 JY8QFUQ01B3CE8 No results +7489 JY8QFUQ01C1ITB No results +7490 JY8QFUQ01BG0J6 No results +7491 JY8QFUQ01DOUX8 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgTtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7492 JY8QFUQ01A47K4 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 639 76.96 167/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (76,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7493 JY8QFUQ01AVL05 No results +7494 JY8QFUQ01DOOGE productive (see comment) Homsap IGHV1-2*02 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggctcctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7495 JY8QFUQ01BLCWW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame - ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7496 JY8QFUQ01C9VGW productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDPFIAATGRPWYFDNW in-frame - ctctggattcaccttcagtagttatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtgataaatactatgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtttctgcaaatgaacagcctgagaagtgaagacacggctgactattactgtgcgaaagacccatttatagcagcaactggccgcccctggtattttgacaactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7497 JY8QFUQ01ASBGD productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7498 JY8QFUQ01BYXZW unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 778 84.72 183/216 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [2.17.38.11] CARERGSGPP#GMDVW out-of-frame - Low V-REGION identity (84,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ggttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaagaggttcgggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7499 JY8QFUQ01B7Q1C productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 923 91.74 200/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - cctctggattccccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaggggccgattcaccatctccagagacaacgccaggaactcattgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7500 JY8QFUQ01C1P2F No results +7501 JY8QFUQ01DNGN1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7502 JY8QFUQ01BRQ4Z No results +7503 JY8QFUQ01CX238 No results +7504 JY8QFUQ01BW1QC productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7505 JY8QFUQ01AN6ZD productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 96.63 201/208 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 6 8 16 6.8.16 [X.17.38.11] CARQIDYGDFSRHGLDVW in-frame + caactttaccggctactggatcggctgggtgcgccagcggcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgataccagatacagcccatccttccaaggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccgtgtattactgtgcgagacaaatagactacggtgacttctctaggcacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7506 JY8QFUQ01C9B7V unproductive Homsap IGHV1-69*02 F, or Homsap IGHV1-69*08 F or Homsap IGHV1-69*11 F (see comment) 610 76.06 162/213 nt 75.59 161/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 1 8 8 X 8.8.X [0.16.38.11] CAKAGFVLATP#DLW out-of-frame - Low V-REGION identity (76,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) cggaggcaacctaaagacctataccataagttgggtgcgacaggccctggacaggggcttgagtggctgggaaggatcaatcctaagattgggagcaacaattatatacagagattgcaggggagagtcacatttactgcggacgagtcgtcgaacacagcctacttgaagctgagtcgcctaaaacctgacgacacgggcgtctatttctgcgcgaaggcgggcttcgttttggcgaccccccggacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7507 JY8QFUQ01AB5D4 productive Homsap IGHV3-7*01 F (see comment) 664 78.97 169/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [0.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (78,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccgagnggtggtgccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7508 JY8QFUQ01DQZ7W productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 773 83.04 186/224 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 13 8.10.13 [1.17.38.11] CATDSPTGYYAFDVW in-frame + Low V-REGION identity (83,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctgggttcgttttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7509 JY8QFUQ01BGQG5 productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7510 JY8QFUQ01DORSO No results +7511 JY8QFUQ01CWUJB No results +7512 JY8QFUQ01A481H productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7513 JY8QFUQ01B9YF9 unproductive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 1 8 7 X 8.7.X [2.17.38.11] CASSVFSPRR#FDYW out-of-frame + stop codons tttcgggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtccccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7514 JY8QFUQ01C2H7F productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1071 99.54 216/217 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARLHGYCGGGYCYDWYFDLW in-frame + ttctggatacagctttaccagctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgattccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgagactccatgggtattgtggtggtggttattgctacgactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7515 JY8QFUQ01BLZDF unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7516 JY8QFUQ01AU0CS productive (see comment) Homsap IGHV3-48*03 F 796 85.65 185/216 nt 84.72 183/216 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-21*02 F 2 7 8 14 7.8.14 [1.17.38.11] CVRQTGDYYFFGLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) ctctggattcgccttcaaagttttaacatgaattgggtccgccaggcttcagggaaggggcCgggagtggattgcatacattaatggaagagggactaacatctactatgcagactctgtgaagggccggttcaccatctccagagacaacgcccagaacgcagtgcatctgcagatggaccgcctgagagtcgaggacacggccctatattactgtgtgagacaaactggagactactatttcttcggtctggacgtctggggccaaggaaccacggtcaccgtctcttcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7517 JY8QFUQ01B5RKV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKRLQAVADDAFDFW in-frame + ctctggattcatctttagtagctatgccatgggctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgagcagcctgagagccgaagacacggccatatattactgtgcgaaaaggttgcaagcagtggctgatgatgcttttgatttctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7518 JY8QFUQ01ASDV1 No results +7519 JY8QFUQ01ALVRH productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7520 JY8QFUQ01BU0SA unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CAREKVRGPP#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaggttcggggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7521 JY8QFUQ01B56OG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7522 JY8QFUQ01DVYMJ unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 971 92.86 208/224 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found stop codons cctctgcagcctcttgattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7523 JY8QFUQ01CS3F4 No results +7524 JY8QFUQ01B33D2 No results +7525 JY8QFUQ01DU681 No results +7526 JY8QFUQ01CLTV6 No results +7527 JY8QFUQ01CTUYQ No results +7528 JY8QFUQ01CPD1V productive Homsap IGHV3-30*07 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - tggattcaccttcaatacctattctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7529 JY8QFUQ01DPQ1L No results +7530 JY8QFUQ01BNHIS No results +7531 JY8QFUQ01BXKWZ productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 7 14 8.7.14 [1.17.38.11] CAREKVRGPPTGMDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaggttcggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7532 JY8QFUQ01AU9HY unproductive (see comment) Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 873 89.4 194/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcatcttcagtgactatggcatgcactgggtccgccagactccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactgggggccaggggaacgctggtcaccgtctcctagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaactggtcgtcgcatgcctggtccagggcttcttccccca +7533 JY8QFUQ01C45R9 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 931 92.59 200/216 nt 91.2 197/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 7 8 16 7.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift) ctctggatcacctttagcagccaTgcccatgtactgggtccgccaagctccagggaaAGggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7534 JY8QFUQ01DQPTM productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagccctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7535 JY8QFUQ01C6FHX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1018 96.35 211/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 10 8.8.10 [2.17.38.11] CTREGFDELGYW in-frame - gcctctggattcacctttagcacctatgccatgagctgggtccgtcaggctccagggaaggggctggagtgggtctcagcgattactggtactggtggtaatacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtacgagagaggggttcgatgaattggggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7536 JY8QFUQ01AXBO8 No results +7537 JY8QFUQ01AOX94 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +7538 JY8QFUQ01C1MKL unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 764 84.19 181/215 nt 83.26 179/215 nt 7 8 X 7.8.X [1.16.38.X] null + No rearrangement found Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) ctctggatccagtttcagtggtttggcgtgaactgggtccgccaggctccagggaagggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagaacagcgccttattcggctacgctaggtacgacgctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7539 JY8QFUQ01BL26X productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactc +7540 JY8QFUQ01CGCSZ unproductive Homsap IGHV1-18*01 F 966 94.86 203/214 nt 94.39 202/214 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [0.17.38.11] CARENLLYFGNSFRLQA#W out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggttacatctttaccacctatggtatcagttgggtgcgacaggCcccctggacaagggcttgagtggatgggatggatcaacacttacaatggtaacacgaactatggacagaggatccagggcagagtcaccatgaccacagacacatccacgagcacagcctacatggagctgaggagcctgagatctgacgacacggccgtatattattgtgcgagagaaaacctactatacttcgggaattcattccggcttcaggcactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +7541 JY8QFUQ01AK8SO productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +7542 JY8QFUQ01A1RK6 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-71*03 P or Homsap IGHV3-72*01 F 283 88.73 63/71 nt 8 X X 8.X.X [1.14.X.X] null + No rearrangement found ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtggg +7543 JY8QFUQ01BN55O No results +7544 JY8QFUQ01A6UKY productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7545 JY8QFUQ01DMPH4 No results +7546 JY8QFUQ01ACCB6 productive (see comment) Homsap IGHV3-11*01 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVDIRLGDWFFDLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'T' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgaccactacatgagctgggtccgccaggctccggggaagggtctggaatggatctcatatatcagtacaagtggtaataTgggtttattacgcggactctgtgaagggccgattcaccgtctccagggacaacaccaagagctcactgtatctgcaaatgaacggcctcagagtcgaggacacggccgtctattactgtgtcgacataagactgggagattggttcttcgatctctggggccgtggcaccctggtaactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7547 JY8QFUQ01CSWKZ productive (see comment) Homsap IGHV3-7*01 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 8 14 7.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) cctctggatttacttttacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7548 JY8QFUQ01C4OV3 No results +7549 JY8QFUQ01BLY5K unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 615 76.64 164/214 nt 75.7 162/214 nt Homsap IGHJ2*01 F, or Homsap IGHJ4*01 F or Homsap IGHJ4*02 F or Homsap IGHJ5*01 F or Homsap IGHJ5*02 F (see comment) 17 71.43 5/7 nt 7 8 X 7.8.X [1.16.38.0] null + stop codons no junction found Low V-REGION identity (76,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*02 and Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides). The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcaccttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactca +7550 JY8QFUQ01A0224 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDNYGDY## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7551 JY8QFUQ01DM6TL productive Homsap IGHV3-7*01 F 873 89.4 194/217 nt Homsap IGHJ3*01 F (see comment) 151 78.0 39/50 nt Homsap IGHD3-16*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARATNADVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagggggtactggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaccataaatcacgatggaagtcaaatttactatatggaccttgtgaagggccggttcaccatctccagagacaacgccgagacctcactctatttgcaaatgaacaccctgagagccgaagacacggctgtctattactgtgcgagggcgactaatgccgacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +7552 JY8QFUQ01AUKP1 No results +7553 JY8QFUQ01BA28B productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7554 JY8QFUQ01AKGZ2 No results +7555 JY8QFUQ01C69SV No results +7556 JY8QFUQ01BWH5D productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7557 JY8QFUQ01CDG42 productive (see comment) Homsap IGHV3-7*03 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 7 8 8 7.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctccggattcattttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtcccaggggcttcttccccca +7558 JY8QFUQ01CD6VQ No results +7559 JY8QFUQ01CDIA1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7560 JY8QFUQ01BLA0C productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7561 JY8QFUQ01CW65U productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + tctacattcacgtttagtcgatattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7562 JY8QFUQ01C0B83 unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CARRGRCG*#YWYFDLW out-of-frame + stop codons tctctagtgactccatcagcagtactaattactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatgtatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgagacgggggagatgcggataactactggtacttcgatctctggggccgtggcaccctggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccc +7563 JY8QFUQ01DJY9E productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame + tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7564 JY8QFUQ01BU7PN productive (see comment) Homsap IGHV4-59*03 F 786 85.51 183/214 nt 84.58 181/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.37.11] CARGRTVVTVVDYVDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 86 of V-REGION: 'C' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 109 in the user submitted sequence), (cause frameshift) tctctggtgactccattagtggttactattggacgtggatccgacagcgcccagggatgagcctggagtggattggacaagtccattacactgggagcaccaagtacagccctccctcaagagtcgagtcaccatttctgttgacatgtccaagaaccCaattcaccctcatcttgacctctgtggccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttgttgactacgttgacttttggggtcagggagtcctggtcaacgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7565 JY8QFUQ01B8WDA No results +7566 JY8QFUQ01B634P No results +7567 JY8QFUQ01BXK4Z productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 928 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 79 to 81 in the user submitted sequence), (do not cause frameshift); gcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7568 JY8QFUQ01CIX1S unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggc +7569 JY8QFUQ01DHF28 No results +7570 JY8QFUQ01BC3YW No results +7571 JY8QFUQ01CUCWJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7572 JY8QFUQ01AP5QK productive Homsap IGHV3-48*03 F 868 89.35 193/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARESWWSGFYGWYDPW in-frame + tctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7573 JY8QFUQ01CMIR9 No results +7574 JY8QFUQ01BZL4J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7575 JY8QFUQ01AKB8K No results +7576 JY8QFUQ01BQTTN No results +7577 JY8QFUQ01AGSPU productive (see comment) Homsap IGHV3-9*02 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.37.11] CGKDMRPGGMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 87 of V-REGION: 2 nucleotides (from position 166 in the user submitted sequence), (cause frameshift) ctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7578 JY8QFUQ01C6SR8 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 645 85.63 149/174 nt 85.06 148/174 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggGggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgc +7579 JY8QFUQ01A0KG1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAIEHTLPSGQGLGIEYFW in-frame + ctctggattcaactttaacagctttgccatgagctgggtccgccaggttccagggatggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactccgtgaagggccggttcaccatctccagagacaactccaacaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgatcgagcatacccttccgtccggacagggattagggattgaatatttctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca +7580 JY8QFUQ01BZ0C2 No results +7581 JY8QFUQ01C4SJ4 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 8 10 8.8.10 [2.17.38.11] CARGDGVKDDYW in-frame - gggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7582 JY8QFUQ01COQYI No results +7583 JY8QFUQ01BC153 productive (see comment) Homsap IGHV3-7*01 F 985 95.37 206/216 nt 94.44 204/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 7 8 11 7.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift)in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) tctctggattcaccttagtaggtttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcccctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7584 JY8QFUQ01A5RRI productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7585 JY8QFUQ01A8SED productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +7586 JY8QFUQ01DJWO6 No results +7587 JY8QFUQ01C0OCC No results +7588 JY8QFUQ01C7LOZ unproductive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDI* in-frame - stop codons Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctagggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7589 JY8QFUQ01APVEB unknown (see comment) Homsap IGHV4-4*07 F 799 86.38 184/213 nt 85.45 182/213 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 6 X 8.6.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 36 of V-REGION: 'TGATGA' (6 nucleotides at position 22 to 27 in the user submitted sequence), (do not cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) gtctggtggctccatcagcagTGATGAttactactggagctggatacggcagtccgccgggaagggactggagtggattgggcgaatttataaagtggcgacacagtgtacaacccctccctcggggggcgagtcgccatgtcactggacacgtccaagaaccaattctccctgaggttgacttctgtgaccgccgaagacacggccgtctattactgtgcgagggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7590 JY8QFUQ01AG9TR productive Homsap IGHV3-7*01 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [2.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame - gcctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7591 JY8QFUQ01BBU5J productive Homsap IGHV4-61*02 F 875 88.69 196/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + tctctggtggccccatcagcagcagcacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +7592 JY8QFUQ01DOFJ6 productive (see comment) Homsap IGHV3-33*05 F (see comment) 752 83.03 181/218 nt 82.57 180/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.16.38.11] CVKGRGYNDYGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaagggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7593 JY8QFUQ01CV2CC productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca +7594 JY8QFUQ01AQ72Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARGPRSRGYGMDVW in-frame - agcctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7595 JY8QFUQ01CD2YV No results +7596 JY8QFUQ01CYZO8 productive Homsap IGHV3-9*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKGGNLGGAVAARYFDYW in-frame + ctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagtggtagcataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagctgaggacacggccttgtattactgtgcaaaagggggtaacctgggtggggcagtggctgcccggtactttgactactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaaccc +7597 JY8QFUQ01C2F28 No results +7598 JY8QFUQ01C11GI No results +7599 JY8QFUQ01AEY2H No results +7600 JY8QFUQ01BLBFT No results +7601 JY8QFUQ01AN4UP productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt 91.59 196/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 97 of V-REGION: 'CG' (2 nucleotides at position 194 to 195 in the user submitted sequence), (cause frameshift); tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaAaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccCGggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggccctatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7602 JY8QFUQ01C3XP4 productive (see comment) Homsap IGHV3-7*01 F 964 93.61 205/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); gcctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggGactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7603 JY8QFUQ01AU26V unproductive (see comment) Homsap IGHV3-48*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDMIIFGGSP*QL# out-of-frame + stop codons cctctggattcaccttcagcagctttagtatgagctggatccgccaggctccagggaaggggctggagtggattgcatacattactaatagaggcactaccacagactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggcagcccttgacaactggggccagggtaaccctggtcaccgtctccgtctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag +7604 JY8QFUQ01AK0IG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7605 JY8QFUQ01BNRVO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [2.17.38.11] CTREVGATDYW in-frame - gcctctggattcagcttcaatagttactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7606 JY8QFUQ01C5TD6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CANELGYCSGG# out-of-frame + ctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgccctggtccagggcttcttccccc +7607 JY8QFUQ01DBR15 productive (see comment) Homsap IGHV3-74*03 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); cctctggattcacGtttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7608 JY8QFUQ01CF6E2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + tctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7609 JY8QFUQ01BSJRI unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 867 89.72 192/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [1.17.38.11] CAKGVVTA#LDYW out-of-frame + ctccggtggctccatcaccagttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatagtgggagcactacctacaactcctccctcaagagtcgagtcaccatatcaggagaagggtccacgcgccagttctccctgaggctgagctctgtgaccgttgcggacacggccgtgtattactgtgcgaagggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7610 JY8QFUQ01DSM83 unknown (see comment) Homsap IGHV4-61*02 F 893 89.59 198/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7611 JY8QFUQ01BSL3T No results +7612 JY8QFUQ01CNMLX productive Homsap IGHV4-4*07 F 903 91.59 196/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 3 8 7 11 8.7.11 [1.17.38.11] CAARNGNVAFNLW in-frame + ctctggcggctccatctatagttactactggagctgggtccggcagcccgccgggaagggactggagtggattgggcgtatctattccaatggggacaccaactacaacccctccctcaagagtcgggtcaccatgtcagtggacgtgtccaacaatgagttctccctgaacttgaggtctgtgaccgccgcggacacggccgtgtattactgtgcggcgcgaaatggaaatgtggcttttaatctgtggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7613 JY8QFUQ01A7PVL unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 130 55.22 74/134 nt 10 9 X 10.9.X [1.17.7.X] null + No rearrangement found stop codons tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc +7614 JY8QFUQ01DUVHH No results +7615 JY8QFUQ01A8ILG No results +7616 JY8QFUQ01DPFSK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 944 93.49 201/215 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARGPRSRGYGMDVW in-frame + ctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcagccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +7617 JY8QFUQ01DDHVF No results +7618 JY8QFUQ01C7PE2 No results +7619 JY8QFUQ01A3D8L unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccaggggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7620 JY8QFUQ01CKR8P productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 859 88.89 192/216 nt 87.96 190/216 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD1-26*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDGGSYNRMDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) gtctgggttcagtttcattgactatggcatacactgggtccgccaggctccaggcAaaggggctggagtggatggcaattatatggtatgatgggaaaataaatattatgaagagtccgtgaaggaccgattcaccgtctccagagacaattccaagaacacggtgtatttggaagtgaatagtctgagagtcgacgacacggctgtgtattactgtgcgagagacggtgggagctacaacaggatggacctttggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7621 JY8QFUQ01BTDAB unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag +7622 JY8QFUQ01DGTB2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDFW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +7623 JY8QFUQ01BAUZH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 813 86.92 186/214 nt 85.51 183/214 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.37.11] CAKESLVRGVISYYFDDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'GAA' (3 nucleotides at position 57 to 59 in the user submitted sequence), (do not cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 131 in the user submitted sequence), (cause frameshift) cctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggGAAagggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctggttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7624 JY8QFUQ01C9O65 No results +7625 JY8QFUQ01DQZTR productive Homsap IGHV3-33*04 F (see comment) 697 80.56 174/216 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7626 JY8QFUQ01DI5X6 productive (see comment) Homsap IGHV3-11*01 F 992 96.7 205/212 nt 95.75 203/212 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD2-2*01 F 2 8 8 12 8.8.12 [0.17.37.11] CAVDCTSISCNGDW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 188 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 102 of V-REGION: 2 nucleotides (from position 208 in the user submitted sequence), (cause frameshift) ctgggttcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggctttcatatattagtagtgctggtagtaccatatactacgcagactctgtgaggggccgattcaccatctccagggacaacaccaagaactcactgtatctgcaaatgaacagcctgaggccgaggacacggccgtgtaactgtgcggtagattgtactagtatcagctgcaacggagactggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7627 JY8QFUQ01DSQGA unproductive Homsap IGHV3-30*07 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDTITMGGDVAPLFDY## out-of-frame + ctctggattcaccttcaggaactatgctatgcactgggtccgccaggctcctggcaaggggctagaatgggtggcttttatatcatatgatggaagtagtcaatactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactgggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +7628 JY8QFUQ01B5QED No results +7629 JY8QFUQ01DCVW2 No results +7630 JY8QFUQ01ASVJP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKGIVGASMQADWFHPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggattcgtctttggcgactatgcgatgagctgggtccggcaggctccagggaTgggggctggagtgggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctagtccagggcttcttccccca +7631 JY8QFUQ01C85DX No results +7632 JY8QFUQ01DAKAC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt 86.11 186/216 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtgcgtggaactca +7633 JY8QFUQ01CWK5E No results +7634 JY8QFUQ01DFTG1 No results +7635 JY8QFUQ01BR38G productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame - cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7636 JY8QFUQ01BZCAL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7637 JY8QFUQ01BPN7S No results +7638 JY8QFUQ01BXMV3 productive Homsap IGHV3-7*01 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + tctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7639 JY8QFUQ01AREM5 productive Homsap IGHV3-72*01 F 1088 98.66 221/224 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-15*01 F 1 8 10 8 8.10.8 [1.17.38.11] CLRPPRYDPW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +7640 JY8QFUQ01BRBZO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7641 JY8QFUQ01AHPMF No results +7642 JY8QFUQ01COP7W No results +7643 JY8QFUQ01CIH47 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 701 80.93 174/215 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [1.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame + Low V-REGION identity (80,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7644 JY8QFUQ01C98TL No results +7645 JY8QFUQ01CHHZ3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 942 92.27 203/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARQSFDFAWQWQVDYYFEYW in-frame - ctctggtggctccgtcagcagtagcacttactactggggctggctccgccagtccccagggaaggctctggagtggattgggactatccatcatagtgggagcacctaccagaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaggaaccagttctccctgaggctgagctctgtgaccgccgcagacacggctctttattactgtgcgagacaaagctttgatttcgcgtggcagtggcaggtagattattactttgaatactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +7646 JY8QFUQ01AXNM5 No results +7647 JY8QFUQ01A110D productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARGRIVAVGMSGWFDPW in-frame - gcctctggattcaccttcagtaactactggatgtattgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggcagtagcacaagctacggggactccgtgaagggccgattcaccgtctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgcgagtcgacgacacggctctatattattgtgcaagaggccgtatagtagcagttgggatgtcaggctggttcgacccttggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7648 JY8QFUQ01CHORL productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame + gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7649 JY8QFUQ01B98D4 productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +7650 JY8QFUQ01CX1TG productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [2.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) tgttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7651 JY8QFUQ01A5WXC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD4-11*01 ORF 3 8 8 17 8.8.17 [1.17.37.11] CAREVTRLTVPYYLYFDLW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 195 in the user submitted sequence), (cause frameshift) ctctggattcccctttagcaactatgacatgaattgggtccgccaggctccagggaaggggctggagtgggtctccggtattagtggtagtggcggtagcacatactacgcagactccgtgaagggccgattctccattaccagagagaatgccaagaactccttgtttcttcaaatgaacagcctgagagccgggacacggctgtttattattgtgcaagagaggtgactagacttactgtcccctattacttatacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7652 JY8QFUQ01BHOD4 No results +7653 JY8QFUQ01B1FVC productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 9 7 12 9.7.12 [1.16.38.11] CAANLGHGSYFKYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) ctctggtgactccgtcagcagtgataactggtggagttgggtccgccagaccccagggaagggctggagtggattggagaaatctatcatggtgggaccaccaactacaatccgtccctcaaaggtcgagtcaccttatcggtcgacaagtccaagaaccaattctctctgagaatgacctcttttaccgccgcagacacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7654 JY8QFUQ01CF3ZO No results +7655 JY8QFUQ01CF06T productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame + gttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag +7656 JY8QFUQ01BCV43 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaAaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7657 JY8QFUQ01DWUWS unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [1.17.38.11] CANASPLYNWN#YFYYYGMDVW out-of-frame + cctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctcccccctgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca +7658 JY8QFUQ01A7OHA unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 931 92.59 200/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRVGAAILRFLEWLSD#NWFDPW out-of-frame + stop codons tctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgctagtactacttccatacactatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggccgccatattacgatttctggagtggctatcagactaactggttcgacccctggggccagggaactctggtcaccgttacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtctcgcctgcctggtccagggcttcttccc +7659 JY8QFUQ01CB4K7 No results +7660 JY8QFUQ01A4Y6U productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7661 JY8QFUQ01ANEIB No results +7662 JY8QFUQ01A2COT productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 915 90.5 200/221 nt 90.05 199/221 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRSEYSSSNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); aggcctctggattccccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcantgaGggggccgattcaccatctccagagacaacgccaggaactcattgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7663 JY8QFUQ01BE8AK productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYYHYDMFGDYW in-frame + ctctggatttacttttagcaactattggatgacctgggttcgccaggctccagggaaggggctggagtgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgcatctgcaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgagagggtcgtattatcattatgatatgttcggcgactactggggccagggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +7664 JY8QFUQ01AUNYM productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7665 JY8QFUQ01CY2WW productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKSPSQVGYYLDCW in-frame + ctctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccggcaaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcaccatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7666 JY8QFUQ01BEIG4 No results +7667 JY8QFUQ01BW0OM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccaggaaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7668 JY8QFUQ01CLADE productive (see comment) Homsap IGHV3-7*01 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtacctttggcatgcactgggtccgccaggctcccgggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc +7669 JY8QFUQ01ARAAW productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7670 JY8QFUQ01AE702 productive (see comment) Homsap IGHV3-7*01 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) cctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7671 JY8QFUQ01C1ALX No results +7672 JY8QFUQ01BYVQ0 productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7673 JY8QFUQ01CO7L9 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 559 78.57 143/182 nt 8 8 X 8.8.X [1.17.26.X] null + No rearrangement found Low V-REGION identity (78,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccgaaccggtgacggtgtcgtggaactcag +7674 JY8QFUQ01DG3UA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKCKAPGKVDWFDPW in-frame - ctctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctggtaaggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7675 JY8QFUQ01CTCZQ unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 923 91.74 200/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKAGVG*YDP#NWFDPW out-of-frame - stop codons cctctggatttaccttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcgggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7676 JY8QFUQ01BMIJH unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 893 89.59 198/221 nt 89.14 197/221 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKSPLSVAGTRQNWFD#PG out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); caggctctgacttGcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctgggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7677 JY8QFUQ01DDCHH No results +7678 JY8QFUQ01BYQ3F unknown (see comment) Homsap IGHV3-64*03 F, or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 179 59.4 79/133 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggcaacgtggtcgtcgcatgcctggtccagggcttcttcccc +7679 JY8QFUQ01AFKF8 No results +7680 JY8QFUQ01BYZ7A No results +7681 JY8QFUQ01CP9M3 No results +7682 JY8QFUQ01AHVIM unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7683 JY8QFUQ01A7VMJ productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgGggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7684 JY8QFUQ01BCN34 productive (see comment) Homsap IGHV1-3*01 F 840 88.32 189/214 nt 87.85 188/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggGggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7685 JY8QFUQ01CDKTG productive Homsap IGHV3-7*01 F 1012 96.76 209/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + tctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7686 JY8QFUQ01ABR4H productive (see comment) Homsap IGHV3-7*01 F 944 93.49 201/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 7 8 6 7.8.6 [1.17.37.11] CVKSIDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 103 in the user submitted sequence), (cause frameshift) ctctggattcacttttagcagttttggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagtgggatggaagtgataaaagtatatggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactatatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtgaaaagcattgactcctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaaggtcttcccgctgagctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7687 JY8QFUQ01CCMJQ No results +7688 JY8QFUQ01C70E3 unknown (see comment) Homsap IGHV4-34*12 F 91 50.97 79/155 nt 8 7 X 8.7.X [1.17.18.X] null + No rearrangement found tctgtggtgggtccttcagtggttactcctggaactgcatccgccagcccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacctcccaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttcccccg +7689 JY8QFUQ01CZPWM unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +7690 JY8QFUQ01BS4F0 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7691 JY8QFUQ01ASLBM productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 935 91.07 204/224 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [1.17.38.11] CTTAPSETYATEYFAMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7692 JY8QFUQ01DHOOC No results +7693 JY8QFUQ01DG6B4 No results +7694 JY8QFUQ01A8T5C No results +7695 JY8QFUQ01A66AU unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 148 53.19 100/188 nt 8 7 X 8.7.X [2.17.28.X] null - No rearrangement found gcctctggattcaccttcagttctcacactatgaactgggtccggcaggctccagggaaggggccggagtgggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7696 JY8QFUQ01DDC8I productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 723 82.24 176/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDWGGSFDRYYFDYW in-frame + Low V-REGION identity (82,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7697 JY8QFUQ01A4KIH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame - tctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7698 JY8QFUQ01A7LKR productive (see comment) Homsap IGHV3-7*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [2.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) gcctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7699 JY8QFUQ01BZOTI unknown (see comment) Homsap IGHV4-61*02 F 884 89.14 197/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7700 JY8QFUQ01DNEIO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + in FR3-IMGT at codon 90 of V-REGION: 'C' (1 nucleotides at position 173 to 173 in the user submitted sequence), (cause frameshift); ctctggattcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgCcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccaggggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttc +7701 JY8QFUQ01CCYDM No results +7702 JY8QFUQ01A730W No results +7703 JY8QFUQ01C8SLA No results +7704 JY8QFUQ01AS292 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7705 JY8QFUQ01AJWQ7 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 949 93.52 202/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 78 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggcGtggagtgggtctctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +7706 JY8QFUQ01C9VPZ unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 903 91.59 196/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [0.17.38.11] CAKAGVG*YDP#NWFDPW out-of-frame - stop codons tggatttaccttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcgggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7707 JY8QFUQ01CWY2U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggcccttgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +7708 JY8QFUQ01AKF88 productive Homsap IGHV3-11*01 F, or Homsap IGHV3-21*04 F (see comment) 378 80.51 95/118 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 X 1 13 X.1.13 [X.X.38.11] CVREVTGVWDWFDPW in-frame + Low V-REGION identity (80,51% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggattcgccttcaactcagtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7709 JY8QFUQ01CIRB3 productive Homsap IGHV3-7*01 F 1012 96.76 209/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARNTPAYWELSGDW in-frame + tctggattcacctttaggagttattggatcagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaacccagatggaagtgagaaatactatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgcgcgaaatacaccggcgtattgggaactatcaggtgactggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7710 JY8QFUQ01CWYA5 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 687 80.37 172/214 nt 79.91 171/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccaCggcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7711 JY8QFUQ01CR7OY No results +7712 JY8QFUQ01DHO6X unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7713 JY8QFUQ01B3ASB No results +7714 JY8QFUQ01DHH8X No results +7715 JY8QFUQ01BJLXZ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); ctccggattcacctttagtagttactggatgcactgggtccgccAaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7716 JY8QFUQ01BCFXE productive (see comment) Homsap IGHV3-30*01 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [2.17.37.11] CARGTMLRGVTKARYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 210 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7717 JY8QFUQ01C7ONV productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7718 JY8QFUQ01CCHPX No results +7719 JY8QFUQ01CY1G4 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame - gttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7720 JY8QFUQ01BUCDU No results +7721 JY8QFUQ01DC796 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7722 JY8QFUQ01C1XF9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7723 JY8QFUQ01A4HGJ No results +7724 JY8QFUQ01A2MU9 No results +7725 JY8QFUQ01DEYBO productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 918 91.71 199/217 nt 90.32 196/217 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 2 8 8 19 8.8.19 [1.16.38.11] CARPAFSGSGTYRPRMAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CCT' (3 nucleotides at position 15 to 17 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tttctggatacagtCCTttagccaattactggatcggctgggtgcgccaggtgcccggaaaggcctggagtggatCggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcagtaccgcctaccttcagtggagcagtctagcgacctcggacaccgccatgtattactgtgcgagaccagctttctctggttcggggacttaccggccgaggatggcttttgatgtctggggccaaggaacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +7726 JY8QFUQ01CPQB9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +7727 JY8QFUQ01CP37E productive Homsap IGHV3-11*01 F 923 91.74 200/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVDIRLGDWFFDLW in-frame - cctctggattcaccttcagtgaccactacatgagttggatccgccaggctccagggaaggggctggagtggatttcatatattagtactagtggtaatatgatttattacgcggactctgtgaagggccgattcaccgtctccagggacaacaccaagagctcactgtatctgcaaatgaacggcctcagagtcgaggacacggccgtctattactgtgtcgacataagactgggagattggttcttcgatctctggggccgtggcaccctggtaactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7728 JY8QFUQ01BYYSI No results +7729 JY8QFUQ01BCMPS productive (see comment) Homsap IGHV4-59*03 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 89 to 94 in the user submitted sequence), (do not cause frameshift); ctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7730 JY8QFUQ01CQGS1 No results +7731 JY8QFUQ01C2EUQ No results +7732 JY8QFUQ01DDV7L productive (see comment) Homsap IGHV3-30*01 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [2.17.38.11] CAGDLTGVPYYYDSSGLKYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctagattcaGccttcagtagctataatatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7733 JY8QFUQ01DKG44 productive (see comment) Homsap IGHV3-7*01 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); cctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7734 JY8QFUQ01BGPYT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtaaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +7735 JY8QFUQ01BR6NC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaacatggaagcgtggtcgtcgcatgcctggtccagggcttcttcccccag +7736 JY8QFUQ01BQ33P unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 671 87.86 152/173 nt 87.28 151/173 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 10 7 X 10.7.X [1.17.22.11] CTNDFQWRYVLR#AFHVW out-of-frame - in FR3-IMGT, from codon 68 of V-REGION: 48 nucleotides (from position 114 in the user submitted sequence), (do not cause frameshift) tctctggtgactccattggtagtagtgcttactactggggctgggtccgccagcccccagggaaggggctcgaatggatagggaatatttactatggtggcagcacctactacaaccagctcttcctggagctgacctctgtgaccgccgcagacacggctctttattactgtacgaacgactttcaatggcggtacgtgctacgcatgctttccatgtctggggccaagggacaatggtcgccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7737 JY8QFUQ01BR8N9 productive (see comment) Homsap IGHV2-5*02 F 874 95.31 183/192 nt 94.27 181/192 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 10 7 14 10.7.14 [9.17.21.11] CAHIRAELSTSCHAFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 81 of V-REGION: 51 nucleotides (from position 172 in the user submitted sequence), (do not cause frameshift) accctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccaggaaAaggccctggagtggcttgcacttgtttattgggatgatgataagcgctacagctcatctctgaagagcagactcaccatcaccaaggacacagccacatattactgtgcacacattagggcggaacttagtaccagctgccatgccttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7738 JY8QFUQ01CD89E No results +7739 JY8QFUQ01CP1DZ unproductive (see comment) Homsap IGHV3-48*01 F 900 90.78 197/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTRQTGNYYYFGVDVW in-frame + stop codons ctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccacctccagagacaatgccaggaattcactgtatctgtaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7740 JY8QFUQ01A3SN3 productive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CATSPSDFDRRWGYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); ctctggatttagctttagaaccttttggatgagctgggtccgccaggctccagggagggggctggagtgggtggccaacataaAagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7741 JY8QFUQ01AM8HH No results +7742 JY8QFUQ01AZB66 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-11*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKSFDYTNFYGLDVW in-frame + ctctggattcacttttagttactatgtcatgagttgggtccgccaggctcccgggaaggggctggagtgggtctcaggtattagtggtattggtgataccgcatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaaggacacactgattctgcaaatgaacagtctgagagccgaggacacggccacttattattgtgcgaagtccttcgactatactaacttctatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcctcaccaagggcccagtcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7743 JY8QFUQ01DIRD2 productive Homsap IGHV3-30*01 F 873 89.4 194/217 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [1.17.38.11] CACGHMRDGYDVW in-frame - ctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7744 JY8QFUQ01BZQC5 productive (see comment) Homsap IGHV4-61*03 F (see comment) 786 85.51 183/214 nt 85.05 182/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD4-17*01 F 2 8 7 13 8.7.13 [1.17.37.11] CARNDHGMWDAFHLW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (8 AA in JY8QFUQ01BZQC5 ; 10 AA in Homsap_IGHV4-61*03) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 211 in the user submitted sequence), (cause frameshift) tctctggtgactctatggcaagctattactggagttggctccggcagcccccaggggagagactggaatggattgggtacatatattccactgggagcaccaactacaacccctcctttaagagtcgagtcaccatttcaatagacaccccgaagaaccacctctccctgaaattgaaatctgtgaccgctgcagacacggccgtgtattttgtgcgaggaacgaccacggtatgtgggatgcatttcatctctggggccaagggacactggtcaccgtcacctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaccgtgacggtgtcgtggaactc +7745 JY8QFUQ01DGA30 productive Homsap IGHV4-61*02 F 956 92.76 205/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame - tctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7746 JY8QFUQ01B76BW productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame + ctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7747 JY8QFUQ01AEM2N productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 849 88.79 190/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 2 8 7 19 8.7.19 [1.17.38.11] CARSSDYLWGSYRYPYYFDYW in-frame + ctctggtgactccatcagtagttacttctggagttggatccggcagcccccagggaagggactggagtggattggatatgtctattacagtggaagtaccaagtataatccttccctcgaaagtcgagtcaccatatcattagacacgcccaacaaccagttctccctgagcctgacctatgtcaccgctgcggacacggccatatactactgtgcgagaagctctgattacctttgggggagttatcgttatccctactacttcgactactggagccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7748 JY8QFUQ01AFJ2C No results +7749 JY8QFUQ01BQV85 No results +7750 JY8QFUQ01C8XGF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7751 JY8QFUQ01B0IGY unproductive Homsap IGHV3-7*01 F (see comment) 783 84.79 184/217 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CARERSAAGVVFFDF# out-of-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaggggctggagtgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgcaaatgaacagcctgcgagtcgaggacacggctgtgtatttctgtgcgagagagagatcagcagctggagtcgtcttctttgacttttggggccagggagcccggtcaccgtctccagagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7752 JY8QFUQ01A51EO No results +7753 JY8QFUQ01A70EP productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [0.17.38.11] CARGFYGDHFDSW in-frame + tggatacaccttcagcgactactacatacactggctgcgacaggcccctggacaacgacttgagtggatgggatggctgaaccctaataatggtgacacagcttatggccagagctttcagggccgggtcaccatgaccagggacacgtccgtcagcacagtgtacgtggaggtgaggaggctgagatctgacgacacagccctttatttctgtgcgagaggcttttacggtgaccactttgactcctggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7754 JY8QFUQ01CET2Z productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 983 87.16 224/257 nt 86.77 223/257 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [14.17.38.11] CAKEQRGSGWSRSALDVW in-frame - Potentially, because of detected insertion/deletion in FR1-IMGT at codon 22 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); cgagtgcgtggagggggcccctgagactctCcctgtgcagcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7755 JY8QFUQ01ASDQE productive (see comment) Homsap IGHV3-74*03 F (see comment) 702 80.65 175/217 nt 80.18 174/217 nt Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRGTTGWRGVDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcaacgtcagtggatactggatgcactgggtccgccaagtgccagggaaggggctggtatgggtctctaggctttcggatgatgaaattactataacttacgcggactttgtggagggccgattcaccatctccagagacaacgccaggaacgaggtctatctgcaaatgaatgatttgagagtcgacgatacggctgtatacttttgtgtgaggggaaccactggctggaggggggttgactactggggccaaggcgccctcgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7756 JY8QFUQ01C77FN No results +7757 JY8QFUQ01CLD99 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 882 89.86 195/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD1-1*01 F 3 8 8 18 8.8.18 [1.17.38.11] CATLNAHAGPGAEWSAFDIW in-frame + ctctggattcagcttcagtctctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcctccattactagtaacagtgattacatatactatgctgactcagtgagaggccgattcaccatctccagagacaactccaagaagtcactgtttctgcaaatgcacagcctgagagccgacgacacggctatctactactgtgcgaccctaaacgcgcacgcgggaccgggagccgaatggtctgcttttgacatctggggccatgggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +7758 JY8QFUQ01ADH3W productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +7759 JY8QFUQ01BX8RV No results +7760 JY8QFUQ01BWF5H productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 798 85.0 187/220 nt 84.55 186/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [2.17.38.11] CVRVKRFGSGNVLFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); aggctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaAagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7761 JY8QFUQ01A9YIB productive Homsap IGHV3-9*01 F (see comment) 788 84.86 185/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CGRIAKPGLGALDLW in-frame - Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcgttggattcacttttaatgaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctggggccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7762 JY8QFUQ01A5ATC productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARELGGSGTCGFDYW in-frame + tggatacaccttcaccaggcactatatgcactgggtgcgacaggcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggggcagagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +7763 JY8QFUQ01C42A6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFD#PW out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7764 JY8QFUQ01B8WYR No results +7765 JY8QFUQ01B8JYP productive (see comment) Homsap IGHV3-11*01 F 867 89.72 192/214 nt 88.79 190/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.16.38.11] CARDPYCSSTNCYPYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) cctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaagggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7766 JY8QFUQ01B5CHG No results +7767 JY8QFUQ01BB80V productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 828 87.1 189/217 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD3-16*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASLNTHAGPGAERSAFDVW in-frame + ctctggattcatcttcagtaactatagaatgaactgggtccgtcaggctccagggaaggggctcgagtgggtctcgtccatcaccagttccagtagttacatctactatgcagactcggtgacgggccgattcaccatctccagagacaactccaaggggtcactctatctgcacatgaacgaccttagggccgaagacacggctgtctattactgtgcgagcctaaacacgcacgcgggaccgggagccgagaggtctgcttttgatgtctggggccgagggacaagggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +7768 JY8QFUQ01BGMBI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-20*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGLTTMTGNGLEHW in-frame + ctctggattcacccttcgcagatatggcatggcgtgggtccgccaggctccggggaaggggctggagtgggtctcatcttctaacagtagtgatgaatccacatactatgcagactccgtgaagggccgcttcaccatttccagagaccattccaagaacacggtgtttttgcaaatgtacagcctgagagccgaagacacggccctctattactgtgcgagagggctaacaacaatgacagggaatggtcttgagcactggggccagggagccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +7769 JY8QFUQ01BTJVV unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 123 68.42 39/57 nt 8 X X 8.X.X [1.9.X.X] null + No rearrangement found ctccggattcacctttagtagttactggatgcactgggtccagggcttcttccccca +7770 JY8QFUQ01BIBQD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7771 JY8QFUQ01CN3GP unknown (see comment) Homsap IGHV4-61*02 F 857 87.78 194/221 nt 87.33 193/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgGggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaatttacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttcggaggttcctacaatttagtggcctactgggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7772 JY8QFUQ01DECQJ No results +7773 JY8QFUQ01DBPKB unproductive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ6*01 F (see comment) 94 61.29 38/62 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSGYYSTGY# out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ1*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7774 JY8QFUQ01CQO2W productive Homsap IGHV4-4*07 F (see comment) 710 80.93 174/215 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-9*01 F 1 10 7 16 10.7.16 [1.17.38.11] WARECLDSLGRPSHLDSW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01CQO2W ; 8 AA in Homsap_IGHV4-4*07), and low V-REGION identity (80,93% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggcccgatcaagaatactgactactattggacatggatccggcagcccgccgggaggggactggagtgggtcgggcgtgtctatttgaatggcaatgccgactacaacccctccttcagcagccgtctcaccatgtccattgacacgtccaggaaccaattctccctgagcttgacctctgtgaccgccgctgacacggccctctattactgggcgagagaatgtcttgattcacttggcagaccgagtcaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7775 JY8QFUQ01AYFLL unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 110 65.52 38/58 nt 8 X X 8.X.X [1.10.X.X] null - No rearrangement found ctccggattcacctttagtagtttctggatgcactgggtccagggcttccttccccca +7776 JY8QFUQ01B06FJ No results +7777 JY8QFUQ01ACGK8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 977 94.5 206/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + cctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtctcccgctgagctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccgag +7778 JY8QFUQ01DQ3B6 No results +7779 JY8QFUQ01DW90Z No results +7780 JY8QFUQ01CLXUH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame + ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggggcttcttccccca +7781 JY8QFUQ01A5S7Z productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + tctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7782 JY8QFUQ01BRKZU unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 472 71.07 140/197 nt 8 7 X 8.7.X [1.17.32.X] null - No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BRKZU ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (71,07% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7783 JY8QFUQ01BYXV7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-11*01 ORF 3 8 8 12 8.8.12 [1.17.38.11] CARASLTKTNFDYW in-frame + tctggattcaccttcagaagttatagcattaactggttccgtcaagctccaggggagggcctggagtgggtctcatccattagtagtaccagttcttacatttactacgcagactcagcgaggggccgattcaccatctccagagacaacgccaataactcagtgtctctgcaaatgaacggcctgagagccgatgacacggctctatatttttgtgcgagagcttccctcactaagacaaactttgactactggggcccgggaacgctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7784 JY8QFUQ01B36Z3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +7785 JY8QFUQ01CH1L2 productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7786 JY8QFUQ01B47WM productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 866 87.78 194/221 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARQRYYESDGQTW in-frame - tctctggtggctccatcaccggaagtagttattattggggctggattcgccagtccccagggaaggggctggagtggattggaagtatgtattacactgggagcaccgactacaacccgtccctcaagagtcgggtcacgatatccgcagacaagtcgaagagccaggtctacctgaagttggactctgtgaccgccgcagacacaggtgtttattactgcgcgagacaaaggtactatgaaagtgatggccaaacctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7787 JY8QFUQ01BTVX2 No results +7788 JY8QFUQ01C0XDT productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt 87.1 189/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.16.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctaaatttgacttcagtgactatggcatgaactgggtccgccaggttccagggaagggctggagtgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7789 JY8QFUQ01B0E54 productive Homsap IGHV3-30*10 F (see comment) 724 81.94 177/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame + Low V-REGION identity (81,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +7790 JY8QFUQ01B9PYF productive (see comment) Homsap IGHV1-2*02 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARWGATWELLLGNLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); tggatacacgttcaccgactactatgtccactgggtgcgacaggcccctggacaagggcttgagtggatggcgtggatcaaccctaacattggtgtcaccaagtctgcacGaaaaatttcagggcagggtcaccatgaccagggacacgtccatcagcacagccttcatggagctgagcagcctgagatctgacgacacggccgtttattactgtgcgagatggggggcgacgtgggaactattattggggaatcttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7791 JY8QFUQ01AKG3P productive Homsap IGHV4-61*02 F 929 91.4 202/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARATLSDVDTPLGFDYW in-frame + tctctggtgtctcaatcacgagtggaagtcactactggaattggattcggcagcccgccgggaagggaccggagtggattgggcgtttctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccgtatcagcagacacgtccaagaaccggctctccctgaagctgagatctttgaccgccgcagacacggctgtttattactgtgcgagagcaaccttgtctgacgtggatacacctttgggctttgactactggggccagggaatcttggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +7792 JY8QFUQ01DP731 unproductive (see comment) Homsap IGHV3-9*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAK*YWGIHMWTIDYW in-frame + stop codons cctctggattcacgtttgatgactatggcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggcattacttggaatagtggttacataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctacagatgaacagtctcagagctgacgacacggccttgtattactgtgcaaaatgatattgggggatacacatgtggaccattgactactggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggctcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +7793 JY8QFUQ01C48H7 productive (see comment) Homsap IGHV3-7*01 F 882 91.83 191/208 nt 91.35 190/208 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*02 F 2 6 8 14 6.8.14 [X.17.38.11] CARGSYYHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'T' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); tcactttagcaactattggatgacctgggttcgccaggctccagggaaggggctggagtgggtggccaacataaaacaacatggaggtgaaaaTgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcaatatatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattatcattatgacaccttcggcgactattggggccagggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7794 JY8QFUQ01CJMPT productive (see comment) Homsap IGHV3-11*01 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARGYSYGCFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'GGAGGGACT' (9 nucleotides at position 89 to 97 in the user submitted sequence), (do not cause frameshift); ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcaaacatcaatagtGGAGGGACTagtgggaggaccatatattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagaggatacagctatggctgctttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7795 JY8QFUQ01BZSKZ productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + ctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7796 JY8QFUQ01AL0S2 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 828 87.1 189/217 nt 85.25 185/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); tgtctctggggactccattagtggttactattggacgtggatccggcagAgccccagggaagggactggagtggattggCaaatgtccattacacCtgggagtaCccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7797 JY8QFUQ01C34Q3 unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*05 F 161 54.49 97/178 nt 8 7 X 8.7.X [1.17.25.X] null - No rearrangement found cctctgcattcaccttcagtagctacgacatgcactgggtccgccaagcaacaggaagaggtctggagtgggtctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7798 JY8QFUQ01C2XW9 productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKEEFDTGWTQPGDW in-frame - ctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7799 JY8QFUQ01B83CF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7800 JY8QFUQ01BMUMM No results +7801 JY8QFUQ01ATS6F productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD3-10*01 F 1 8 8 19 8.8.19 [1.17.38.11] CARPAFLWFGDLPAEDGFDVW in-frame + ttctggatacagctttaccaattactggatcggctgggtgcgccaggtgcccggaaaaggcctggagtggatggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcagtaccgcctaccttcagtggagcagtctagcgacctcggacaccgccatgtattactgtgcgagaccagcttttctctggttcggggacttaccggccgaggatggttttgatgtctggggccaaggaacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7802 JY8QFUQ01B7RE7 productive Homsap IGHV3-9*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7803 JY8QFUQ01BG0ZX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcgaccctgggctgcctggtcaaggactacttccccgaaccggtgacggtntcgtggaactca +7804 JY8QFUQ01AP5BZ No results +7805 JY8QFUQ01CQ57N productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7806 JY8QFUQ01B1PFE unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 112 53.73 72/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7807 JY8QFUQ01BU0AP No results +7808 JY8QFUQ01BC1SJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDFFIGGYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt +7809 JY8QFUQ01A0HBC unknown (see comment) Homsap IGHV3-48*01 F 1080 100.0 217/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7810 JY8QFUQ01AR2I9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7811 JY8QFUQ01DLM3X productive (see comment) Homsap IGHV2-5*02 F 1152 97.13 237/244 nt 95.9 234/244 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 3 10 7 15 10.7.15 [9.17.38.11] CAQKGEIDTYGPKYDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'AC' (2 nucleotides at position 189 to 190 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttctctgggttctcactcagcactagtggagtGgggtgtgggctgcatccgtcagGcccccaggaaaggccctggagtggcttgcactcatttattgggatgatgataagcgctacagtccatctctgaagagcagactcaccatcaccaaggacacctccaaaaaACcagggtggtccttacaatgaccaacatgaaccctatggacacagccacatattactgtgcacagaagggggaaatagacacctatggccccaaatatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +7812 JY8QFUQ01DCW6Z No results +7813 JY8QFUQ01DLZFY unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 100 66.67 32/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*RRP*LL# out-of-frame + stop codons ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggctggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtntcctcagatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttccccca +7814 JY8QFUQ01B41S4 unknown (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggtcgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7815 JY8QFUQ01BJS3C unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 277 62.87 105/167 nt 8 10 X 8.10.X [2.17.20.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (10 AA in JY8QFUQ01BJS3C ; 8 AA in Homsap_IGHV3-7*01), and low V-REGION identity (62,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcactttcactaacgcctggatgagctgggtccgccaggctccagggaaggggctggagtggattggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7816 JY8QFUQ01CAXWI unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 203 93.48 43/46 nt 8 X X 8.X.X [1.6.X.X] null - No rearrangement found ctctggattcagatttagcagctatggcatgagctgggtccgccag +7817 JY8QFUQ01B32WV unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*02 F or Homsap IGHV3-33*03 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F or Homsap IGHV3-64*01 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 121 54.48 73/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons gtctggattcaccttcagtagctacggcatgcactgggtccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7818 JY8QFUQ01AV8RW productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcatctttgatgattttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7819 JY8QFUQ01C185F productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*07 F 818 85.27 191/224 nt 84.82 190/224 nt Homsap IGHJ5*02 F 110 69.39 34/49 nt Homsap IGHD1-26*01 F 2 8 10 5 8.10.5 [1.17.38.11] CREAIAW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctgggttcgtgttcggtaacttctttatgaattggttccgccagcctccgggaaAaggggctggagtgggttggccgcatcaaaaccaaagttgatggtgagacaacagactacgctgcagccgtgaaagacagattcatcatttcaagagatgattcaaaaaatacgatgtatctgcaaatgaacgacctgaagaccgaggacacggccgtatattattgtcgggaggccatcgcgtggggccagggaaccctggtcaaggtctcatcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7820 JY8QFUQ01B0MQR productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7821 JY8QFUQ01BR1K2 productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDYFDSW in-frame - tggatacaccttcaccgactacttcatacactggctgcgacaggcccctggacaacgacttgagtggatgggatggatcaaccctaagaatggtgacacaaagtatgcacagaactttcagggccgggtcaccatgaccagggacacgtccgtcagcaccatatatgtggaggtgagcagcctggaatctgacgacgcagccacttattactgtgcgagaggcttttatggtgactactttgactcctggggccagggagccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7822 JY8QFUQ01C79FO productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1025 97.67 210/215 nt 96.74 208/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARGGGYYFVAIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaagtggGgagcaccaactacaaccCcctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7823 JY8QFUQ01AJ94F productive (see comment) Homsap IGHV3-7*01 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 7 8 6 7.8.6 [1.17.38.11] CSRLLEEW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctccggattcattttggtgactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccg +7824 JY8QFUQ01ATLE6 No results +7825 JY8QFUQ01B0H63 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 813 86.92 186/214 nt 86.45 185/214 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKESLVRGVISYYFDDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) ctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggtttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctggttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7826 JY8QFUQ01AW1RT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7827 JY8QFUQ01ACX8S No results +7828 JY8QFUQ01AUJ6M productive (see comment) Homsap IGHV3-7*01 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.16.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) tctacattcacgtttagtcggtattggatgagctggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7829 JY8QFUQ01BEKUJ unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P 82 53.47 54/101 nt 8 8 X 8.8.X [1.17.X.X] null + No rearrangement found stop codons ctctggattcaccgtcagagataactacgtgacctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccac +7830 JY8QFUQ01C3FFW unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7831 JY8QFUQ01CAPJ8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7832 JY8QFUQ01AXSRV unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYFGTL#DYW out-of-frame + stop codons gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttggaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7833 JY8QFUQ01AXU31 productive Homsap IGHV3-23*05 F, or Homsap IGHV3-66*03 F or Homsap IGHV3-NL1*01 F (see comment) 387 78.74 100/127 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 X 4 9 X.4.9 [X.X.38.11] CARDQVTEDYW in-frame - Low V-REGION identity (78,74% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctacattcgcctttagcaactatgccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7834 JY8QFUQ01BJDMV No results +7835 JY8QFUQ01BY9B6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 3 8 8 14 8.8.14 [1.17.38.11] CAKVGVMSARDRIDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); cctctggattcaccGtttagcaactatgccatgagttgggtccgccaggctcaagggaaggggctggactgggtctcagatattagtaatagtggtggtgacacattctacgcaggctccgtgaagggccgcttcaccatctccagagacaattccaggaacactctatatctgcaaatggacagcctgagagccgaggacacggccgtgtattactgtgcgaaagtgggggtgatgtccgctcgagaccgcattgactactggggccggggaaccctggtctccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7836 JY8QFUQ01BQOVD No results +7837 JY8QFUQ01BMC7N productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 829 86.76 190/219 nt 85.39 187/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'CA' (2 nucleotides at position 55 to 56 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) cctccgggagttcaccttagtagtttctggatgcactggGgtccggcaagttccCAaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7838 JY8QFUQ01BPXZS productive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARCPNYNIGTRGFDYW in-frame + tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7839 JY8QFUQ01DIM81 productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDYFDSW in-frame - tggatacaccttcaccgactacttcatacactggctgcgacaggcccctggacaacgacttgagtggatgggatggatcaaccctaagaatggtgacacaaagtatgcacagaactttcagggccgggtcaccatgaccagggacacgtccgtcagcaccatatatgtggaggtgagcagcctggaatctgacgacgcagccacttattactgtgcgagaggcttttatggtgactactttgactcctggggccagggagccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7840 JY8QFUQ01A3NLN productive (see comment) Homsap IGHV3-7*01 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 7 8 11 7.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtaggtttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7841 JY8QFUQ01AFX9B No results +7842 JY8QFUQ01CE8P9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CGKPIVGATGREMPVSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagcaactatgccatgaactgggtccgccaggttccaggggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7843 JY8QFUQ01BMCQC unproductive (see comment) Homsap IGHV3-72*01 F 823 85.33 192/225 nt 84.44 190/225 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-8*02 F 2 8 10 17 8.10.17 [2.17.38.11] CTRDTTDTGGQSFNGLDVW in-frame - stop codons Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'A' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); acctcagggttcgctttttgagaAatacaccatgagttgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaAagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctggggccaggggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7844 JY8QFUQ01BMES9 No results +7845 JY8QFUQ01CDC8F productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7846 JY8QFUQ01BK1FK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1040 97.71 213/218 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGPHQYYFDYW in-frame + cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactactttgactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +7847 JY8QFUQ01A0DHK unknown (see comment) Homsap IGHV3-23*03 F (see comment) 253 78.31 65/83 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found Low V-REGION identity (78,31% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggtccagggcttcttccccca +7848 JY8QFUQ01CK11N productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.24 188/218 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVKEDHDSGLRVLLEW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggagggggctggantgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7849 JY8QFUQ01BVH2P No results +7850 JY8QFUQ01AUQ27 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagaaaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +7851 JY8QFUQ01AO88B No results +7852 JY8QFUQ01AGJ8R No results +7853 JY8QFUQ01CXWNZ No results +7854 JY8QFUQ01A95LP No results +7855 JY8QFUQ01CSQWT No results +7856 JY8QFUQ01DFD03 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARKRVPGGDFFMG##YW out-of-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccgggggggacttttttatgggggaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7857 JY8QFUQ01A9QZP unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 872 89.77 193/215 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - caggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgcttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaagtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7858 JY8QFUQ01A3VWR No results +7859 JY8QFUQ01BLT2J productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 986 94.95 207/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 8 15 8.8.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame + cgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7860 JY8QFUQ01CYKN1 No results +7861 JY8QFUQ01C4L9S unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARKRVPGGTFLW#DYW out-of-frame - cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggacctttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7862 JY8QFUQ01ANTCO productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7863 JY8QFUQ01DOR32 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7864 JY8QFUQ01AF1BX No results +7865 JY8QFUQ01ASIM9 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 971 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 66 of V-REGION: 'G' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); tctggattcactttcagnagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacaGccctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcatcccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7866 JY8QFUQ01BVO71 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7867 JY8QFUQ01CFU9Z productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 7 8 15 7.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7868 JY8QFUQ01A34ZH productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*02 F 3 8 8 19 8.8.19 [1.17.38.11] CARLPFIVVVTGAFLGHFDYW in-frame - gttctggatacacgtttatgaattactggctcggctgggtgcgccagatgcccggcaaaggcctggagtggatggggatcatctttcctgctgactctgatgcccgatacagcccgtccttccaaggccaggtcaccatctcaatcgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacgccgccatatattactgtgcgagactcccctttattgtggtggtgactggtgcgtttttgggacactttgactattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7869 JY8QFUQ01AWT78 productive (see comment) Homsap IGHV1-24*01 F 952 94.37 201/213 nt 93.9 200/213 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD3-16*01 F 2 8 8 11 8.8.11 [X.17.38.11] CVGDVGWGYPQGW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ggatacaccctcaatgaattatccatgcactgggtgcgacagactcctggaaaagggcttgagtcgatgggcggAttttgatcctgaatatggtaaaacaatctacgcgcagaagttccagggcagagtcaccatgaccgaggacacatctgcagacacagcctacatggagttgagaagcctgagatttgaggacacggccgtgtattattgtgtcggagatgtcggctggggatacccccaaggctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7870 JY8QFUQ01DCFJM productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + ctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +7871 JY8QFUQ01DL2T3 No results +7872 JY8QFUQ01AUVXR productive Homsap IGHV3-48*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CARDVPGPNDNYFDYW in-frame + ctctggattcagcttcagagactatggcatggcctgggtccgccaggctccagggaaggggctggagtgggtctcatacattggtaggattattagtgacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagggacgacgacacggctgtctatttctgtgcgagagatgtcccgggccccaatgacaactactttgactactggggccagggaaccctgcttaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggctccagggcttcttccccca +7873 JY8QFUQ01B19Q4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 590 89.73 131/146 nt 89.04 130/146 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-10*01 F 3 8 6 X 8.6.X [1.17.16.11] CAKKYHYGSGSYLYSFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 64 of V-REGION: 71 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) ctctgggttcacctttgcccactttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtggtgatgattccacaaatggacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactcctttgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaagggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7874 JY8QFUQ01BF6QF unproductive Homsap IGHV4-39*02 F (see comment) 704 80.09 177/221 nt 79.64 176/221 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD3-10*01 F 3 10 7 X 10.7.X [1.17.38.11] CAIHNYYGSGRNYFDH## out-of-frame - Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'A' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggagtctccgccatcggcaccagttccttctAggggctgggtccgccagcccccagggaaggggctggagtggatcggagctgttcattacagtggaagtatctcttacacgccggccctcaagagtcgactcaccatgtccttagacacgtcaaaaggtcacttgtccctgagactgacctcagtgacctccgcagacacggctatgtactactgtgccatacacaactactatggatcggggagaaactactttgaccactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7875 JY8QFUQ01DE9OH No results +7876 JY8QFUQ01A3QYQ No results +7877 JY8QFUQ01CT5W5 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 977 94.5 206/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAKDFTYAFDLW in-frame + cgtctggattcacgttcagtagttatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatcatctggtatgatggaagtaatcaatattatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacggtgtatctacaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgaaagattttacgtacgcctttgatctctggggccaagggacaatggtcaccgtctcttcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7878 JY8QFUQ01BL4EI productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 892 89.95 197/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) ggcctcctggattcacCctttggttattatggcatgactgggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7879 JY8QFUQ01BG66X productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKVYTGAWGDPNFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcagctttagcaactttgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtacttttagcacccattatgccgactccgtgaagggccgcttcaccatctccagagacaatttcaggagcaccttatatctgcagatgaacaacctgagagccgacgacacggccatatattactgtgcgaaagtgtacaccggtgcctggggggatcctaattttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7880 JY8QFUQ01DRDEK unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDSRAGGYPNGYFYYXGLDV## out-of-frame - in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); cctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataGggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattacnctggtctggacgtctggggccgaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7881 JY8QFUQ01A8M23 No results +7882 JY8QFUQ01AGECL unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 985 93.33 210/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 9 X 10.9.X [1.17.38.11] CARGVIIMIVVV#DYW out-of-frame - tctcgggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagaggggtgattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7883 JY8QFUQ01BK6SR No results +7884 JY8QFUQ01C4C3G productive (see comment) Homsap IGHV3-7*01 F 1022 96.79 211/218 nt 96.33 210/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGcctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7885 JY8QFUQ01C8XAC productive (see comment) Homsap IGHV3-7*01 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaAaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +7886 JY8QFUQ01DL701 No results +7887 JY8QFUQ01BFRHA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7888 JY8QFUQ01CGDK6 productive Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7889 JY8QFUQ01DK30C unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 828 87.1 189/217 nt 86.18 187/217 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD6-6*01 F 2 7 7 X 7.7.X [2.17.38.11] CVRSYSRTSEFDY## out-of-frame - in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) gcgtctggattcagttcagtacctttggcatgagttggatccgccagacgccaggcaaggggctggagtgggtgacagttatatggtcggatggactcaaaaaaattatgcagactccgtgaagggccgattcaccatctccagagacaatgtcaagaacacggtttatctgcagatgagcagcctgagagtcgaggacacgggcgtatattattgtgtgaggtcgtatagtaggacatctgagtttgactactggggccccgggaacccaagtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7890 JY8QFUQ01C6FNP No results +7891 JY8QFUQ01CT9X8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7892 JY8QFUQ01ARPA7 No results +7893 JY8QFUQ01BG3AX productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 913 91.67 198/216 nt 90.74 196/216 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [2.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); gcttctgggttcaccgtcagtagcaaGgttcatgagctgggtccgccaggctccagggaaTggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7894 JY8QFUQ01AM5G9 No results +7895 JY8QFUQ01AIRZ3 productive Homsap IGHV3-23*05 F (see comment) 447 83.08 108/130 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 X 5 16 X.5.16 [X.X.38.11] CVRYDYSRLHRSNYFGPW in-frame - Low V-REGION identity (83,08% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcatcagttatgactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7896 JY8QFUQ01BGDYH unproductive Homsap IGHV3-NL1*01 F (see comment) 312 70.77 92/130 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 X 5 X X.5.X [X.X.38.11] VREIPYLGRQRL#YHFDYW out-of-frame + Low V-REGION identity (70,77% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattctccttcagaagttactctttccactggggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttattttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7897 JY8QFUQ01BETIR productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7898 JY8QFUQ01C5ZGW productive Homsap IGHV3-11*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame - ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggctttcatacattagtggtagtggaactaccatatcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaggaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgaggcgggtgtggggatatagttatggttccgtttcgtactactttgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7899 JY8QFUQ01CWFYY No results +7900 JY8QFUQ01CR93I No results +7901 JY8QFUQ01CTXUJ productive Homsap IGHV4-59*02 F 930 92.99 199/214 nt Homsap IGHJ3*02 F 169 82.0 41/50 nt Homsap IGHD4-23*01 ORF 3 8 7 15 8.7.15 [1.17.38.11] CARRFTVERGKDAFDIW in-frame + ctctggtggctccgtcactaataactactggagctggatccggcagcccccagggatgggactggagtggattgggtatatccataacagtgggacctccaactacaacccctccctcaagagtcgagtcaccatatcactagacacgtccaagagccagttctccctgaacctggggtctgtgaccgccgcggacacggccgtctattactgtgcgagacgctttacggtggagaggggaaaagatgcttttgatatctggggccacgggacaatggtcaccgtgctcttcagcctccaccaagggcccatggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +7902 JY8QFUQ01DW9T6 productive (see comment) Homsap IGHV3-33*04 F (see comment) 684 79.72 173/217 nt 78.8 171/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'AC' (2 nucleotides at position 207 to 208 in the user submitted sequence), (cause frameshift); atttggattccctttcagcgactatggcatgcactGgggtccgccaggctccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctACtttacttattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7903 JY8QFUQ01A476X productive Homsap IGHV3-11*01 F 945 93.09 202/217 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD2-21*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARGKMVSTGMDVW in-frame + Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) ctctggattcacgtttagtgactactacatgacctggattcgtcaggctccagggaagggcctggagtgggttacatatattagtagtagtggtggtaacacacattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaacgcactgtatctgcaaatgaacagcctgagggccgaggacacggccgtgtattactgtgcgcgagggaagatggtgagcaccggtatggacgtctggggccaagggaccacggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +7904 JY8QFUQ01BAR1C productive Homsap IGHV3-9*01 F 891 90.32 196/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD3-22*01 F 2 8 8 26 8.8.26 [1.17.38.11] CVKDHGVTYFYDSVGYVSGAYNYAMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcacctttgatgattttggcatgcactgggtccggcaagttccagggaagggcccggagtgggtcgcaggtattagttggaatggtggacatatggactatgcggactctgtgaagggccgattcaccgtgtcccgagacaacgccgagaattccctgtatctgcaaatgaacagtctgacacctgaagacacggccctgtattactgtgtaaaagaccatggcgtcacttacttttatgacagtgttggttatgtctccggggcgtacaactacgcaatggacgtctggggccaggggacgacggtcaccgtctcctcagcctccaccaaggggccccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7905 JY8QFUQ01CAD79 No results +7906 JY8QFUQ01CCPYE unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 895 90.74 196/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - stop codons ctctgattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7907 JY8QFUQ01BS51T productive Homsap IGHV4-39*03 F 929 91.36 201/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7908 JY8QFUQ01BQU68 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKEEGATGVYYVDH# out-of-frame - in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); tctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagAccctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactgggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7909 JY8QFUQ01DPLFH productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F (see comment) 785 84.16 186/221 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-9*01 F 2 10 7 11 10.7.11 [1.17.38.11] CARILDGYFFDPW in-frame - Low V-REGION identity (84,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcgacactcaaaattactactggggctggattcgccagcccccagggacgggactggagtgggttggcagtgtccgctatggcgagagcacctattacaacccgaccctcaaaagtcgactcaccatatccatagacacgtccaggagccagttatccctgagactgagttctgtcaccgccgccgacacggcagtttactactgtgcgaggatcttggatggttacttcttcgacccctggggccagggaacccacgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7910 JY8QFUQ01DDRAT unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARKRVPGGNFLM#DYW out-of-frame + cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggaactttttgatggggactactggggccagggaaccctggtcaccgtctcctcagccgtccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccttgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +7911 JY8QFUQ01CDUPC No results +7912 JY8QFUQ01AAXU5 No results +7913 JY8QFUQ01CNDRT unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1044 98.16 213/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CANYYDSSGYRD* in-frame + stop codons ctctggattcacctttagaagttatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtagtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaattattatgatagtagtggttatagagactagggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +7914 JY8QFUQ01AHBK2 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 858 89.25 191/214 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7915 JY8QFUQ01BRBQF No results +7916 JY8QFUQ01AWTSB No results +7917 JY8QFUQ01A6QOY No results +7918 JY8QFUQ01B4DMT unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 131 83.78 31/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ttctggattcgcctttagccgttatgccatgacttgg +7919 JY8QFUQ01BF7VE productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7920 JY8QFUQ01CW1LU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaaggacccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7921 JY8QFUQ01B8L20 No results +7922 JY8QFUQ01A5SGC unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-10*01 F 3 7 8 X 7.8.X [1.17.38.11] CVRRGMVAGRYD##FDIW out-of-frame - stop codons in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) cctctggatcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcagccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgccttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7923 JY8QFUQ01B3L4U productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggcGtggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7924 JY8QFUQ01BISI7 productive Homsap IGHV3-30*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDYEDCRGGRCYAEPLDYW in-frame + cctctagattcaccttcagtagctataatatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgaaagattacgaggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +7925 JY8QFUQ01DOA8W productive (see comment) Homsap IGHV3-30*01 F 887 89.91 196/218 nt 88.99 194/218 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 7 8 11 7.8.11 [2.17.38.11] CACGHMRDGYDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtgccttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtCaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7926 JY8QFUQ01DF6DK unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1008 96.31 209/217 nt Homsap IGHJ4*03 F 69 60.42 29/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDTLEVVSNMDDAFDV# out-of-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaaggacaatggtcaccgtctctcagcattccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7927 JY8QFUQ01CJP19 productive Homsap IGHV3-9*01 F 1036 97.26 213/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-20*01 F 3 8 8 13 8.8.13 [2.17.38.11] CAKDMGYTWKYIDHW in-frame - gcctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattacttggaacagtggtaggataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattattgtgcaaaagatatggggtatacctggaagtacattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7928 JY8QFUQ01CD227 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7929 JY8QFUQ01C3KNU unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); cctccggattcaccGtttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaagacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7930 JY8QFUQ01CMPV8 productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1015 95.5 212/222 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 10 7 12 10.7.12 [2.17.38.11] CARHPLGESFFEYW in-frame - gtctctggtggctccatcagcagtggcgcttactactggagctggatccgccagcacccagggaagggcctggagtggattgggcacatctatgacagtgggagcaccaactacaacccgtccctcaagagtcgagtttccatatcaatagacacgtctaagagccacttctccctgaagctgagctctgtgactgccgcggacacggccgtgtatttctgtgcgagacatccgcttggggagagcttctttgagtactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7931 JY8QFUQ01AMZO0 No results +7932 JY8QFUQ01AH6R0 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 914 93.3 195/209 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 6 8 18 6.8.18 [X.17.38.11] CARHRDYGGQSWFYHGMDVW in-frame + atagtttcaccagatactgggtcggctgggtgcgccagatgcccgggaaaggcccggagtggatggggatcatctatcctgatgactctgataccagatacagtccgtccttcaaaggccaggtcaccatctcagccgacaagtccatcagtaccgcctacctgcagtggaacagcttgaaggcctcggacaccgccttgtattattgtgcgagacatagggactacggtggtcaatcctggttctaccacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7933 JY8QFUQ01CJBM7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame - cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7934 JY8QFUQ01B3GJ1 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1023 96.36 212/220 nt 95.91 211/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [2.17.38.11] CARPGVGASSFIDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); gggttctggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaAaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7935 JY8QFUQ01BYV6J No results +7936 JY8QFUQ01DB0H7 No results +7937 JY8QFUQ01DVVCU unknown (see comment) Homsap IGHV3-7*02 F 914 91.28 199/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaacgactactggggccagggaaccctgggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactcttcccccgaaccgggtgacggtgtcgtggaacctcagg +7938 JY8QFUQ01CB0IE No results +7939 JY8QFUQ01CG6HK productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagGggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7940 JY8QFUQ01B6DDX productive Homsap IGHV3-7*03 F 846 88.02 191/217 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcatttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca +7941 JY8QFUQ01DUA1Y productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7942 JY8QFUQ01CGXPC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactanttccccgaaccggtgacggtgtcggatgactcga +7943 JY8QFUQ01CS5I4 No results +7944 JY8QFUQ01B2WQ3 No results +7945 JY8QFUQ01AXL0Y unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-13*01 F 1 8 7 X 8.7.X [2.17.38.11] CARGVGQQLPPLD## out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift); gtctctcgtgcctccatcaatacCtttttactGggagctggatccggcagcccccagggaagggactggagtggattggatatatctatgatagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatctatagacacgtccaagaaccagttctccctgaggctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagaggggtggggcagcaactgccccccttagactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7946 JY8QFUQ01BJB2Q No results +7947 JY8QFUQ01DEDM3 productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1020 95.52 213/223 nt 94.17 210/223 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD2-15*01 F 3 8 10 19 8.10.19 [1.17.38.11] CARHGRDSSEVMVGGYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'G' (1 nucleotides at position 176 to 176 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtggctctgctatgcactgggtccgccaggcttccgggaAaagggctggaatgggttggccgtattagaagcagagcttacagttccgcgacagcatatgcagcgtcggtgaaaggcaggttcaccatttccagagatgattcaaagaacacggtgtGatctgcaaatgaacagtttgaaaaccgaggacacggccgtgtattactgtgctagacatggaagggactccagtgaagtgatggtaggtggatacggcatggacgtctggggccaagggtccacggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7948 JY8QFUQ01ALNIQ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 266 67.72 86/127 nt 8 8 X 8.8.X [1.17.8.X] null - No rearrangement found Low V-REGION identity (67,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7949 JY8QFUQ01B0042 No results +7950 JY8QFUQ01C5QTX productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7951 JY8QFUQ01DLKL1 productive (see comment) Homsap IGHV3-48*01 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); tctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggTtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7952 JY8QFUQ01CM1OS No results +7953 JY8QFUQ01AL23O No results +7954 JY8QFUQ01AS3JQ unproductive Homsap IGHV3-48*01 F 896 90.37 197/218 nt Homsap IGHJ1*01 F (see comment) 107 67.31 35/52 nt Homsap IGHD2-21*01 F 2 8 8 X 8.8.X [1.17.38.11] CARESTWEFTPDS## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattcagtttcagtgactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagttctagtagtaccctatattatgcagactctgtgaagggccgattcaccgtctccagagacaatgacaagagttctctgtatctgcaaatgaccggcctgagagccgaagacacggcgacttattactgtgcgagagagtcgacgtgggaatttactcctgactcctggggcccgggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7955 JY8QFUQ01BCEKR unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag +7956 JY8QFUQ01A8GCA No results +7957 JY8QFUQ01BMTRL unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 123 68.42 39/57 nt 8 X X 8.X.X [1.9.X.X] null - No rearrangement found ctctggattcacctttagtaaccattggatgaactgggtccagggcttcttccccca +7958 JY8QFUQ01BTQ0D productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7959 JY8QFUQ01BRZ9W unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1075 100.0 216/216 nt 99.07 214/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.16.38.11] CAKDRITIF#YNWFDPW out-of-frame - in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagcGtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatatttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7960 JY8QFUQ01DQSAI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +7961 JY8QFUQ01CCAFD productive (see comment) Homsap IGHV4-61*02 F (see comment) 568 73.18 161/220 nt 72.27 159/220 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [1.16.38.11] CARECSNSKVGPRALDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (73,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 102 of V-REGION: 'A' (1 nucleotides at position 214 to 214 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tttctggtggcccgatcaaaagtcctgattaccattggacgtggatccggcagccnccgggaaggggctggagtgggtcgggcgtgtctatatgactggctatgtcgagaacaatccatccctctccgggcgtctctccatgtcgattgacacggcgaagaatcagttttctatgacattgacttctgtgaccgccgcagacacggccctttaAtttttgtgcgagggagtgtagtaattcgaaagtcggaccgagagcgcttgactcctggggcccgggaagtctggtcaccgtatcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7962 JY8QFUQ01AI6TS No results +7963 JY8QFUQ01A5WTA No results +7964 JY8QFUQ01CAQFC unknown (see comment) Homsap IGHV3-7*03 F 837 87.1 189/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcatgtttagtaactattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagaaagatggtagtgagacttactatgtggaatctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagccagggaacccaggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7965 JY8QFUQ01C6JPE productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 8 13 8.8.13 [1.17.38.11] CATYGRFSFSPLDYW in-frame + ctctggattcacctttagcagctatgccatgaactgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctccccttgactactggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7966 JY8QFUQ01B6CY0 productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ3*02 F 160 80.0 40/50 nt Homsap IGHD3-22*01 F 2 8 7 11 8.7.11 [1.17.38.11] CAGRNGNLAFNIW in-frame + atctggtggttcgatcgtcagttactactggagttggatccggcagtccgccgggaagggactggagtggattgggcgcatctactccaatggagatacgaactacaatccctccctcaagggtcgagtcaccatgtcagtagacccttccaacaaccagttctccctgaaattgacttctgtgaccgccgcggacacggccatatattactgtgcgggaagaaatggaaatttggccttcaatatttggggccaagggacaaatgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7967 JY8QFUQ01BU37Y No results +7968 JY8QFUQ01CSBH4 productive Homsap IGHV3-7*01 F 928 91.78 201/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGFYSTGYW in-frame - gcctctggcttcacctttgaaaattatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7969 JY8QFUQ01C20VU productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7970 JY8QFUQ01DSS92 No results +7971 JY8QFUQ01BQ2BT No results +7972 JY8QFUQ01BSZ5N No results +7973 JY8QFUQ01AWVZM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +7974 JY8QFUQ01BAN3Z No results +7975 JY8QFUQ01C2FP7 unproductive Homsap IGHV3-7*01 F 938 91.86 203/221 nt 91.4 202/221 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CARGAGAEGKGGMDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); tagcctctggattcacctttagtaattattggatgagctgggtccgccaggctccagggaagggactggagtgggtggccaatataaagcaagatggaagtaagaagcactatgtggactccgtggagggccgattcaccatcaccagagacaacaccaaaaGactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctgggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7976 JY8QFUQ01B8GND No results +7977 JY8QFUQ01CS6B3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 870 88.64 195/220 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 2 10 7 16 10.7.16 [1.17.38.11] CTNDRSMAVRATHAFHIW in-frame - ctctggtgactccattggtagcagtgcctactactggggctgggtccgccagccccccgggaaggggctggagtggattggaagtatctattatggtggcaacacctactacaacccgtccctcaggagtcgagtcagcatttccgcagacacgtccaagaaccagttctccctgcatctctactccgtgaccgccgcagacacggctctgtattactgtacgaatgaccgttcgatggccgttcgtgcaactcatgcttttcatatctggggcctagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7978 JY8QFUQ01BKHHN productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7979 JY8QFUQ01CORR8 No results +7980 JY8QFUQ01CSE5B productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 912 92.06 197/214 nt 91.59 196/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 3 8 8 12 8.8.12 [1.17.37.11] CAKGRGVTRYFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 86 of V-REGION: 3 nucleotides (from position 161 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcgactatctcatgggctgggtccgccaggctccagggaaggggctggagtgggtctcgagtattagtggtagtgatggtaccacatattacgcagactccgtgaagggccggttcaccttctccagagacaattccaagaagatgtatttgcaaatgaacaccctgagagtcgaggacacggccgtatattactgtgcgaaaggacggggcgtcacccggtactttgactactggggccagggagccctggtcatcgtctcgtcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag +7981 JY8QFUQ01B4UWJ No results +7982 JY8QFUQ01A7B3N unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - stop codons in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); ctctggattcacctttaacaactaCggccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7983 JY8QFUQ01BLT04 productive (see comment) Homsap IGHV3-7*01 F 1014 95.91 211/220 nt 95.45 210/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); aggctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7984 JY8QFUQ01ASQ0V productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7985 JY8QFUQ01DRCXR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7986 JY8QFUQ01DT1WQ productive (see comment) Homsap IGHV3-7*03 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [2.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gcctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaAaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7987 JY8QFUQ01C0C6D unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 432 92.93 92/99 nt 91.92 91/99 nt 8 7 X 8.7.X [1.16.X.X] null + No rearrangement found in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtaggggtgttgaca +7988 JY8QFUQ01B3AFX No results +7989 JY8QFUQ01AY29M unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 93 52.27 69/132 nt 8 6 X 8.6.X [1.17.11.X] null + No rearrangement found ctctggattcaccttcagctcccattggatgagctgggtccgccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +7990 JY8QFUQ01B8PWI unproductive Homsap IGHV3-7*01 F 895 90.74 196/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKARIYFMVRGVIP#FDYW out-of-frame + tctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctattttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7991 JY8QFUQ01AJFHX unknown (see comment) Homsap IGHV1-NL1*01 P 84 56.41 44/78 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccaga +7992 JY8QFUQ01DHQ9W productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame - cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +7993 JY8QFUQ01ABF66 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7994 JY8QFUQ01BHEKS unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 814 86.57 187/216 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-2*01 F 1 8 7 X 8.7.X [2.17.38.11] CGTSSRAWA#DAFDIW out-of-frame - gcctctgggctcagcgtcagtaactaccgcatgggctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagagatgatagtacagatcatgtagattccgtgaagggccgattcaccgtttcccgagacaattccaagaacacattgtaccttcagatgaacagtgtgacagccgaggacacggccgtttattattgtggaactagttcccgcgcctgggcgctgatgcctttgatatctggggccaggggacactggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +7995 JY8QFUQ01AD5WM productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7996 JY8QFUQ01AFPP1 unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 993 96.26 206/214 nt 8 8 X 8.8.X [0.17.38.X] null + No rearrangement found tgaatacagttttaccagttcctggatcgcctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgataccagatacagtccgtccttcaaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgagggcctcggacaccgccatgtattactgtgcgggcactcaagtgggagctaagggggggattccactggttcttcgatttctggggtcccgtggcacccctggtcactggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +7997 JY8QFUQ01CNHUT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +7998 JY8QFUQ01C0HRE productive Homsap IGHV3-11*01 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame - tctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +7999 JY8QFUQ01AFM6J No results +8000 JY8QFUQ01BJQFO No results +8001 JY8QFUQ01DADSF No results +8002 JY8QFUQ01A6VPK productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaggaattattactggagctggatccggcagTcccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8003 JY8QFUQ01CFJ2D No results +8004 JY8QFUQ01AWP5I productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 696 80.84 173/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +8005 JY8QFUQ01B7OCJ No results +8006 JY8QFUQ01CIP7Q unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 783 84.33 183/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8007 JY8QFUQ01DOVL5 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 945 93.09 202/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8008 JY8QFUQ01DSAKD productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8009 JY8QFUQ01CBVQ5 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 981 94.93 206/217 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARQSVPYTEYFNWFDPW in-frame + gtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcagggggctggagtgggtggcaattatatggcatgatggaaccaataaatactatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacagtgtatctgcaaatgaatagcctgagagccgaggacacggctgtgtattattgtgcgagacagtctgtaccatataccgaatatttcaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8010 JY8QFUQ01BR5YQ No results +8011 JY8QFUQ01DRZGS No results +8012 JY8QFUQ01CUVWM unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSDFYSTGPL# out-of-frame + ctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggcccactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8013 JY8QFUQ01B19RC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +8014 JY8QFUQ01BKWOZ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 7 8 13 7.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattcccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaggggccgattcaccatctccagagacaacgccaggaactcattgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8015 JY8QFUQ01ALBIK unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDLRARLWHPMDV# out-of-frame + ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctgggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc +8016 JY8QFUQ01BFWPX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 930 91.03 203/223 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [3.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tgtagcctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8017 JY8QFUQ01AG86T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8018 JY8QFUQ01AQZD7 productive (see comment) Homsap IGHV4-61*02 F 888 89.55 197/220 nt 88.18 194/220 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.16.38.11] CAREHSRTMGGARELDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'T' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) tctctggtggccccatcagcagcagcacttactactggacttggatGccggcaggccgccgggagggactggagtggatcggacgtgtttatactTagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcctgggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8019 JY8QFUQ01CRMUC unproductive Homsap IGHV3-33*03 F 927 92.17 200/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDGEQWLVWTL#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8020 JY8QFUQ01A6GU8 unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8021 JY8QFUQ01COR9K unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKQKS*LW#YYFDQW out-of-frame + stop codons ctctggattcacgtttaaaacacatgccatgagctgggtccgccaggctccaggaaaggggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaaatcatagttatggatactactttgaccagtggggccagggaacccgggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8022 JY8QFUQ01ATZYG No results +8023 JY8QFUQ01COYRM productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8024 JY8QFUQ01A4OAA No results +8025 JY8QFUQ01AMKU1 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 200 59.46 88/148 nt 8 8 X 8.8.X [1.17.15.X] null + No rearrangement found tctggattcacctttgacagccatgccatgcactgggtccgtcgggctccagggaaggggctggagtgggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8026 JY8QFUQ01DCBVS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 8 10 8.8.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttctccgaaccggtgacggtgtcgtggaactcag +8027 JY8QFUQ01DHDYL productive (see comment) Homsap IGHV3-69-1*02 P 919 93.33 196/210 nt 92.86 195/210 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-20*01 F 3 8 7 10 8.7.10 [1.16.38.11] CARDDKWAFDYW in-frame + Potentially, because of detected insertion/deletion however the closest V is a pseudogene in FR2-IMGT, from codon 55 of V-REGION: 3 nucleotides (from position 76 in the user submitted sequence), (do not cause frameshift) tctggattcaccttcagtgactacagcatgaactgggtccgccaggctccagggcaggggctggagtgggtctcatatagtcgcggaagaaccacatactacgcagactctgtgcagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgacagccgaggacacggctgtttattactgtgcgagagatgataagtgggcatttgactactggggccagggaaccctggtcgtcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +8028 JY8QFUQ01C5FW0 No results +8029 JY8QFUQ01BPKJH No results +8030 JY8QFUQ01DBDVA productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +8031 JY8QFUQ01CHSF6 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 94 52.24 70/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8032 JY8QFUQ01A3C67 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtcgttatagcatgaactGgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccggctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +8033 JY8QFUQ01CY0SI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctgatcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8034 JY8QFUQ01CTNMI productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 3 8 8 10 8.8.10 [1.17.38.11] CASFRVLESGYW in-frame + ctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8035 JY8QFUQ01CQ95F productive Homsap IGHV3-9*01 F 968 93.58 204/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDAMGGAGDWAAFGIW in-frame - cctctggcttcatctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagcgctaccatagaatatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctggaaatcaacagtctgagacctgaagacacggccttatactactgcgcaaaagatgcgatgggaggagctggtgattgggctgcttttggtatctggggccaggggacaatggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8036 JY8QFUQ01B1HSK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + cctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8037 JY8QFUQ01AAW8M No results +8038 JY8QFUQ01CNTH5 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1040 97.71 213/218 nt 97.25 212/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [2.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8039 JY8QFUQ01AZUMD No results +8040 JY8QFUQ01BJUKC productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1038 98.6 211/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8041 JY8QFUQ01BGUH5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 973 94.06 206/219 nt Homsap IGHJ6*02 F 212 87.27 48/55 nt 8 8 10 8.8.10 [2.17.38.11] CARDRYYVVDVW in-frame - gcctctggattcaccttcagtgccacctggatgcactgggtccgccaagctccagggcaggggctggtgtgggtctctcatattaatggtgatgggagtagcacaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacggtgtatttgcaaatgaacagtctgagagccgaggacacggctgtatactactgtgcaagagatcgatactacgttgtggacgtctggggccaagggaccacggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8042 JY8QFUQ01C06U8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); agcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggGtattagtggtagtggtgataGgaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8043 JY8QFUQ01CU10Q No results +8044 JY8QFUQ01BCBNG productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYHFDYW in-frame + ctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +8045 JY8QFUQ01AHKNO productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDLYDSSGSFDYW in-frame + ctctggattcaccttcagcagctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtaggagtagtaccaaaaactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgcgagagatttgtatgatagtagtggttcttttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8046 JY8QFUQ01C1IUN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8047 JY8QFUQ01CXU56 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtGactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8048 JY8QFUQ01B9YQF No results +8049 JY8QFUQ01CFUNF unproductive Homsap IGHV3-48*04 F (see comment) 939 93.46 200/214 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-13*01 F 1 8 7 X 8.7.X [1.17.38.11] CARGRIVSVGMSG#FDPW out-of-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CFUNF ; 8 AA in Homsap_IGHV3-48*04) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtagttataccatgcactgggtccgccaggctccagggaaggggctggaatgggtctcatccattagtagtagtactaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctgttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8050 JY8QFUQ01AC900 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8051 JY8QFUQ01AJYVB productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8052 JY8QFUQ01CDH83 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD4-23*01 ORF 1 8 7 X 8.7.X [1.17.38.11] CARLTTAVGGWS#LDIW out-of-frame + tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttggatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggttcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcancgcctgcctggtcagggccttccttccc +8053 JY8QFUQ01B12N8 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-59*08 F 881 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-9*01 F 2 8 7 15 8.7.15 [2.17.38.11] CARDRRISAGYYDFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); gtctctggtggcGtccatcaatacgcactactggagttggatccggnagaccccagggaagggactggagtggattggatatatccatcacagtgggtacactaactacagcccctccctcaagagtcgagccaccatatcattagacacgtcgaagaaccagttctccctgaaactgggctttgtgaccgccgcggacacggccgtttattactgtgcgagagaccgtaggatttcggctggttattatgactttgatatctggggccaagggacaatggtcatcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +8054 JY8QFUQ01A18YR productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 891 90.32 196/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-9*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARGGVDILTGFYDAFDIW in-frame + ttctggatacagctttggcaccgcctggctcggctgggtgcgccagacgcccgggaaaggcctggagtggatggggaccatccatcctgctgactctgatacaaaatacagcccgtccttccaggcccaagtcaccatctcggtcgacaggtccatcaacaccgcctacctgcagtggagcagcctggaggcctcggacaccgccatgtatttctgtgcgcggggaggagtcgatattttgactggtttctatgatgctttcgatatctggggccaagggaccatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag +8055 JY8QFUQ01CMVZ1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8056 JY8QFUQ01ARMWR unknown (see comment) Homsap IGHV1-69*06 F, or Homsap IGHV1-69*10 F or Homsap IGHV1-69*14 F 809 86.51 186/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctggagacaccttcagtagccaagccatcagctgggtgcgacaggcccctggacaaggacttgagtggatgggcgggatcatccctatttttgatatgacgaggtacccacagaggttcgagggcagaatcacgattaccgcggacacgtccacgaccacactttacatggaactgagcagcctgaggtctgaggacacggccgtgtatttttgtgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8057 JY8QFUQ01BI60V unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 981 94.93 206/217 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDNYGDYW# out-of-frame + ctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8058 JY8QFUQ01CTJ46 productive Homsap IGHV3-30*01 F 815 86.24 188/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD5-12*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDFDTDDVGTYW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggattcatcttcgatagttatgctctgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttgtttcatatgatggaaaatataagcaatatgcagattctgtggagggccgattcaccatctccagagacaactccaagaacacaggatatctgcaaatgaacagcctgacatctgacgatacggctgtgtatttttgtgcgagagacttcgatactgacgacgtgggcacctactggggccggggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8059 JY8QFUQ01CNNKZ unknown (see comment) Homsap IGHV3-7*02 F 182 79.31 46/58 nt 8 X X 8.X.X [1.10.X.X] null - No rearrangement found ctctggattcaacttcagaacctattggatgggctgggtccgccaggcttcttcccca +8060 JY8QFUQ01CRI2C No results +8061 JY8QFUQ01DWXUL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 396 77.04 104/135 nt 76.3 103/135 nt 8 6 X 8.6.X [1.17.12.X] null + No rearrangement found Low V-REGION identity (77,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 97 in the user submitted sequence), (cause frameshift) ctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8062 JY8QFUQ01CH5IG productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8063 JY8QFUQ01CYG8J No results +8064 JY8QFUQ01BVES5 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ2*01 F 76 60.38 32/53 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKENYFESSGYHGMN#LG out-of-frame + ctctggattcacctttaccaactatgccatgacctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtaatcgtggtactggagtgtactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagagccgaggacacggccctttattactgtgcgaaagagaattactttgagagtagtggttatcacggtatgaacgtctggggccagggggtaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag +8065 JY8QFUQ01B7EJZ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.37.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8066 JY8QFUQ01C3AE4 productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.49 197/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtCgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8067 JY8QFUQ01C1M1T unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8068 JY8QFUQ01BSEFR unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 140 78.26 36/46 nt 8 X X 8.X.X [1.6.X.X] null - No rearrangement found ctctggattcagcctcgccacttatagtatgagttgggtccgccag +8069 JY8QFUQ01BB900 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 447 93.14 95/102 nt 8 7 X 8.7.X [1.17.X.X] null + No rearrangement found cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgaca +8070 JY8QFUQ01CUSF5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8071 JY8QFUQ01AF7VN unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPGGNCLL*WW*#CYDPW out-of-frame + stop codons ctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggaattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8072 JY8QFUQ01A9FXS productive (see comment) Homsap IGHV3-48*03 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagttcttatgccatgaactgggtccgcctggtccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8073 JY8QFUQ01DRVVN productive Homsap IGHV1-69*02 F 836 87.91 189/215 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD2-8*01 F 2 8 8 20 8.8.20 [0.17.38.11] CARGYCTNGVCYRGSYNWLDPW in-frame - tggagggcccctccggcagttataccatcaactgggtgcgacaggcccctggacaagaccttgagtggatgggaaggatcatccctacccttggcatagtaaactacgcacagaagttccagagcagagtaacgattaccgcggacaagtggacgagcacaatcttcatggagctgagcaacctgagacctgaggacacggccgtgtattattgtgcgagaggatattgtactaatggtgtgtgttatcgcggctcgtacaactggctcgacccctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8074 JY8QFUQ01C8AM7 No results +8075 JY8QFUQ01BURT1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + tccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8076 JY8QFUQ01C00TS No results +8077 JY8QFUQ01C14RP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 874 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [2.17.38.11] CAKDASRYYYNSYCDNW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 213 to 213 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttaCtttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8078 JY8QFUQ01CCMOO unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDY## out-of-frame + cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggcccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8079 JY8QFUQ01AEVNR No results +8080 JY8QFUQ01BDZEL productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.16.38.11] CATDDSNGWDEVADYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttGcagctcccattggatgagctgggtccgccagactccagggaagggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8081 JY8QFUQ01CLMHR productive (see comment) Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 99.07 214/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8082 JY8QFUQ01BYA3F productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggGggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8083 JY8QFUQ01A49FA No results +8084 JY8QFUQ01ANH7N unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 89.86 195/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.16.38.11] CAKN*GVGDG##WYFDFW out-of-frame + stop codons in CDR2-IMGT at codon 57 of V-REGION: 'ACT' (3 nucleotides at position 83 to 85 in the user submitted sequence), (do not cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) cctctggattcgactttagcggctttgccatgagctgggtccgccaggcccagggaaggggctggagtgggtctcaactattACTaatggtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttatttctgtgcgaaaaattagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +8085 JY8QFUQ01BHWWB unknown (see comment) Homsap IGHV4-59*04 F, or Homsap IGHV4-59*08 F (see comment) 259 57.75 123/213 nt 57.28 122/213 nt 8 6 X 8.6.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (57,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtgggacactacctacaactcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8086 JY8QFUQ01A7PBA productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8087 JY8QFUQ01DORI9 No results +8088 JY8QFUQ01CFSIW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +8089 JY8QFUQ01CMFB0 productive Homsap IGHV3-30*10 F (see comment) 724 81.94 177/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame - Low V-REGION identity (81,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8090 JY8QFUQ01CSDLR No results +8091 JY8QFUQ01B5PCZ productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8092 JY8QFUQ01BD41F No results +8093 JY8QFUQ01A026U unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame + ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccc +8094 JY8QFUQ01BSEQP productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +8095 JY8QFUQ01AXXBY productive Homsap IGHV3-48*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacatggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8096 JY8QFUQ01DBCCE unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 120 53.9 76/141 nt 10 7 X 10.7.X [1.17.11.X] null - No rearrangement found stop codons tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8097 JY8QFUQ01CLXOH productive Homsap IGHV3-11*01 F 968 94.04 205/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CARDPHRGDGCTYDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtgactaccacatgggctggatccgccaggctccagggaaggggctggagtgcgtttcatacattagcactagtggtcgtgacatatacaacgcagactctgtgaagggccgattcaccatctccagggacaacgcccagaagtcactgtatctgcaaatgaacagcctgagagccgaggacacagccgtgtatttctgtgcgagggatccccatcgtggagatggctgcacttacgactcctggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8098 JY8QFUQ01CYT4N No results +8099 JY8QFUQ01A98NE productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 858 89.25 191/214 nt 88.79 190/214 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.16.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtggctccatgaggaattattactggagctggatccggcagtccccaggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8100 JY8QFUQ01BH6G8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.16.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) ctctggattcacctttaccacctccgccatggcctgggtccgccaggtccagggaaggggctggagtgggtctcaactattagacctagtagtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8101 JY8QFUQ01BIPQI No results +8102 JY8QFUQ01B4JXT productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8103 JY8QFUQ01BP0Z3 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +8104 JY8QFUQ01AN3IA productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1008 96.31 209/217 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDVW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8105 JY8QFUQ01C9NOK unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +8106 JY8QFUQ01CBRI8 No results +8107 JY8QFUQ01CRA87 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 639 76.96 167/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (76,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8108 JY8QFUQ01C36VJ No results +8109 JY8QFUQ01CFINT productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8110 JY8QFUQ01AEIRN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame - gtctctggatttacctttagcagttatgccatgaactgggtccgccaggctccagggaaggggctgcagtgggtctctggtattagtggtggtggtgatgacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8111 JY8QFUQ01A5KVX productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctcgtgcctccatcaatactttttacCtggagctggatccggcagcccccagggaagggactggagtggattggatatatctatgatagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatctatagacacgtccaagaaccagttctccctgaggctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8112 JY8QFUQ01CMFKW productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8113 JY8QFUQ01AN3MM productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1045 95.61 218/228 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [2.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + tctccgggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggc +8114 JY8QFUQ01BBS4B No results +8115 JY8QFUQ01AJC34 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcagcttcagtacctataacatgaactGgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8116 JY8QFUQ01BZLI4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8117 JY8QFUQ01DCVP6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 178 to 178 in the user submitted sequence), (cause frameshift); ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatTggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8118 JY8QFUQ01C8M0C No results +8119 JY8QFUQ01A7R1F No results +8120 JY8QFUQ01C9FNF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8121 JY8QFUQ01C8IS7 No results +8122 JY8QFUQ01CTJ74 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 2 7 8 10 7.8.10 [2.17.38.11] CAKDFTYAFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) gcgtctggattcacgttcagtagtatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatcatctggtatgatggaagtaatcaatattatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacggtgtatctacaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgaaagattttacgtacgcctttgatctctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +8123 JY8QFUQ01AYQPD productive Homsap IGHV3-7*01 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 2 8 8 18 8.8.18 [0.17.38.11] CSRHGGYTKLYNQNVYLDYW in-frame - ctggattcacatttagcaacttttggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaaaataaacccagtcggaagtgagaaatactatgtggactctgtgaagggccgattcaccacctccagagacaactctagaaactcgctgtgtctgcaaatggacagcctgagagccgaggacacggctgtgtattactgttcgagacatggaggttacacgaaactctacaatcaaaatgtctaccttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8124 JY8QFUQ01CXEFI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 978 94.09 207/220 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAIEHTLPSGQGLGIEYFW in-frame - agcctctggattcaactttaacagctttgccatgagctgggtccgccaggttccagggatggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactccgtgaagggccggttcaccatctccagagacaactccaacaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgatcgagcatacccttccgtccggacagggattagggattgaatatttctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8125 JY8QFUQ01B3XB9 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 935 93.02 200/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'AG' (2 nucleotides at position 73 to 74 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggctgggatgggtcAGtctggtataatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8126 JY8QFUQ01BYTOD productive (see comment) Homsap IGHV4-61*02 F 978 94.09 207/220 nt 93.18 205/220 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD5-18*01 F 3 10 7 18 10.7.18 [1.16.38.11] CARVRARSNSHPGHSWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagcagcagtagGttactactcgacctggctccggcagcccgcggaaagggaccggagtggattgggcatatctatagtagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcggacacggccgtgtattactgtgcgagagtgagggcgcgcagtaatagtcaccccggccacagctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8127 JY8QFUQ01BM7EF unproductive Homsap IGHV3-11*01 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARRRDYGDYGDGFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 81 of V-REGION: 'G' (1 nucleotides at position 147 to 147 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccaggGgacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8128 JY8QFUQ01A9PRA No results +8129 JY8QFUQ01AD5TZ No results +8130 JY8QFUQ01B0D43 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 840 90.24 185/205 nt 89.27 183/205 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 9 nucleotides (from position 14 in the user submitted sequence), (do not cause frameshift) ctctggtgactcccacttctggagctggatccggcagcccccgggaaagggcctggagtggattggttatgtctataacagtgGggaccaccaactacaacccctccctcaggagtcgagtcaccatgtctatagacacgtccaagaagcagatctctctgaggttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactcctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +8131 JY8QFUQ01BWEM0 No results +8132 JY8QFUQ01DITVH unknown (see comment) Homsap IGHV1-2*02 F 487 86.72 111/128 nt 8 8 X 8.8.X [0.17.9.X] null + No rearrangement found tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcaggg +8133 JY8QFUQ01B2KZQ productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 956 92.76 205/221 nt 91.86 203/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 7 10 10 7.10.10 [1.17.38.11] CTHLREEMSYEW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) tctggagtcaattcagaaacgcctggatgaattgggtccgccaggctccagggaAaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgtctggtccagggcttcttccccca +8134 JY8QFUQ01DDWWU No results +8135 JY8QFUQ01B2DWQ No results +8136 JY8QFUQ01CI2X3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 956 92.76 205/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARRGSYGSGSYYPW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggcgccatcagcagtaatagttactactgggactggatccgccagcccccagggaaggggctggagtggattgggagtatgttttatactggggtcaccttctacaacccgtccctcaagagtcgagttaacatttccgtggacacgtccaagagccagttctccctgaggctgagctctgtgaccgccgcagacacggctgtgtatcactgtgcgagacgtggttcctatggttcggggagttattatccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8137 JY8QFUQ01C3YTB No results +8138 JY8QFUQ01B84QO productive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'C' (1 nucleotides at position 144 to 144 in the user submitted sequence), (cause frameshift); ctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtgGgactctgtgaagggccgattcaccatctcCcagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8139 JY8QFUQ01AJOT0 No results +8140 JY8QFUQ01C8EAO productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'T' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattTacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8141 JY8QFUQ01AWIKP productive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame + ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +8142 JY8QFUQ01AJ1AE unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 115 53.57 75/140 nt 10 7 X 10.7.X [1.17.11.X] null - No rearrangement found stop codons ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8143 JY8QFUQ01DW6MJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [1.17.38.11] CVKDRDFLWGTYRLQLEHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacttttagcagccatatgatgagctgggtccgccagactccagaaaaggggcttgaatgggtctcaggcatcaatgataacggtcgaagcataaactacgcgggctccgtgaagggccggttcaccatctccagagacaattccaagagcacgttgtatctgcagatggatagcctgagccccgaggactcgggcatatattattgtgtgaaagatcgtgatttcctttggggcacttatcgtcttcaacttgaacattggggccagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8144 JY8QFUQ01C28M8 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD1-26*01 F 1 8 7 16 8.7.16 [1.17.38.11] CAKGIVGASMQADWFHPW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaagggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctncctggtccagggcttcttccccca +8145 JY8QFUQ01BO8TT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CANEVGYCSGGG in-frame + ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatcgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8146 JY8QFUQ01A3V06 unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CARRRGLNYYSFMDVW# out-of-frame + ctctggatacagcttcgccaactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatcgatcctagtgactctgataccagatatagcccgtccttccaaggccaagtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgcaggcctcggacaccgccacgtattactgtgcgagacggcggggccttaactactactcctttatggacgtctgggggccaagggacccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +8147 JY8QFUQ01BD99G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8148 JY8QFUQ01A4X8T productive Homsap IGHV3-9*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + ctctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8149 JY8QFUQ01BDE5S productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 827 87.44 188/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccgggggcacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8150 JY8QFUQ01BLEDM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 15 8.8.15 [2.17.38.11] CVRGGVSGAFRWGFDYW in-frame - gcctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgacgacacggctgtttactactgtgtgagagggggagtcagtggggccttcaggtgggggtttgactactggggccagggaaccctggccaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgcttcaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8151 JY8QFUQ01C9L0R unproductive (see comment) Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 8 X 8.8.X [1.17.38.11] CARGAPIL** (see Functionality comment) out-of-frame + stop codons, IMGT/JunctionAnalysis gives no results for this JUNCTION ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatattactgtgcgagaggggcccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +8152 JY8QFUQ01B8RK3 No results +8153 JY8QFUQ01DKJ92 productive (see comment) Homsap IGHV3-48*02 F (see comment) 739 81.74 179/219 nt 81.28 178/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [2.17.38.11] CARSTDGYYDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,74% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattccCccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8154 JY8QFUQ01BZL35 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame + gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaact +8155 JY8QFUQ01B7ZVC No results +8156 JY8QFUQ01C53V7 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt 94.88 204/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); ctggattcaccttcagGtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8157 JY8QFUQ01CGH13 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaAaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8158 JY8QFUQ01A3QW2 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtactaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattattgtgcaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8159 JY8QFUQ01DVPP5 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8160 JY8QFUQ01DF6Z2 No results +8161 JY8QFUQ01BTJ17 No results +8162 JY8QFUQ01CZGL8 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8163 JY8QFUQ01BWJDF productive (see comment) Homsap IGHV4-34*03 F, or Homsap IGHV4-34*10 F 862 89.62 190/212 nt 89.15 189/212 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 228 94.12 48/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.37.11] CVRNYYDFSGYFNWFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 121 in the user submitted sequence), (cause frameshift) ctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacaatccgtccctcaaagtcgagtcaccgtgtcttcagacacgtccaagaatcagttctccctggagttgatctctgtgaccgccgcggacacggccatatattattgtgtgagaaattactatgattttagtggttatttcaattggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +8164 JY8QFUQ01BHH3Z No results +8165 JY8QFUQ01DCQJH No results +8166 JY8QFUQ01BB5QD productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 896 90.37 197/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) gcctcctggattcacCctttggttattatggcatgactgggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8167 JY8QFUQ01BL843 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 797 85.32 186/218 nt 84.86 185/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-10*02 F 2 8 8 13 8.8.13 [1.17.38.11] CAKERDNNVLPVDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 83 of V-REGION: 'T' (1 nucleotides at position 153 to 153 in the user submitted sequence), (cause frameshift); cctctggattcagcttcaatagttatactttgagttgggtccgccaggctccagggaaggggctggagtgggtctcagctatcagtggaacaggtgaaacaaccttctacgcggactccgtgaggggccggttcaccgtctccagagacaatTtccaagaatactctgtacttgcaattgagcgacctgagagccgaagacacggccgtctattactgtgcgaaggagagagataacaatgttctgcccgttgactcctggggccagggaaccctggtcaccgtctcctcagatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttccccca +8168 JY8QFUQ01DG8N5 No results +8169 JY8QFUQ01BCDHW No results +8170 JY8QFUQ01AS38N productive (see comment) Homsap IGHV4-59*10 F, or Homsap IGHV4-61*02 F (see comment) 555 71.62 164/229 nt 71.18 163/229 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [6.17.37.11] CARERDKSGGGAGDFDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (71,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 226 in the user submitted sequence), (cause frameshift) tctccagtggcattgttaatggcgaaggttttggtcgtttctactggaactgggtccggcagatcgacgggcaggggctagagtggatcgggcgtgtttatcgtgatgggatcacaaactacaatccctccttcgggacccgaataagtttgtcgttagactcgtccaagaggcagttttccctggagttacagtctgtgaccgccgcagacacggccttatattttgtgcgagggagcgtgacaagtcgggcggcggggcgggcgactttgactcctggggccagggactcctggtcaccgtctcatctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8171 JY8QFUQ01B4U0H No results +8172 JY8QFUQ01CEQAI unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 79 62.0 31/50 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW# out-of-frame + stop codons ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggcccaatgggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +8173 JY8QFUQ01B5FJ1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARGHSYYVSSGPDYW in-frame - agcctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8174 JY8QFUQ01BR5DD productive Homsap IGHV3-9*02 F 891 90.32 196/217 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + ctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccggaccagccccaaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccga +8175 JY8QFUQ01CH7UC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8176 JY8QFUQ01BM1BY No results +8177 JY8QFUQ01B2YNB productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8178 JY8QFUQ01A0Z8P unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 89 51.88 69/133 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons tctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8179 JY8QFUQ01CWUWJ productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame + ctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8180 JY8QFUQ01CTCJT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +8181 JY8QFUQ01APX9E productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 999 95.85 208/217 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDVW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccaaggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8182 JY8QFUQ01AOCQ8 No results +8183 JY8QFUQ01A9GRS productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [2.17.38.11] CARAPRTATLLDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); gtctctggcgactccatcagtggtcacCtactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8184 JY8QFUQ01COKT6 unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSGF*LDG#YW out-of-frame + stop codons ctctggattcacctttagtgactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttaactcgacgggctactggggccagggaaccctggtcaccgtctcctctgcatccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +8185 JY8QFUQ01CKTYZ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatagcggctcgtccgactacactagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8186 JY8QFUQ01B75LO No results +8187 JY8QFUQ01DBQSW unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGVRGVGAYYIYYF#DLW out-of-frame + ctctggattcacctttggcctctatgccatgaactgggtccgccagactccagggaaggggctggagtggctcgcaactattagtggtagtggaagtagatcattttacgcagactccctgaagggccggttcaccatctccagagacaattccaagggcacggtatacctggaaatgaccaccctgagagccgaggacacggccgtatattactgtgcgagagatggggtccgtggcgttggtgcttactacatctactattttcgacttatggggccagggaaccctggtcactgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8188 JY8QFUQ01DO1TK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8189 JY8QFUQ01DOK8Y productive Homsap IGHV4-61*02 F (see comment) 596 74.66 165/221 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD3-10*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARECSNSKVGPRALDSWG in-frame + Low V-REGION identity (74,66% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tttctggtggcccgatcaaaagtcctgattaccattggacgtggatccggcagcccgccgggaagggactggagtgggtcggacgtgtctatatgactggttatgtcgaccacaatccatccctctccgggcgtctcaccatgtctatcgacacctcgaagaatcaattttctatgacattgacctctgtgaccgccgcagacacggccctatatttttgtgcgagggagtgtagtaattcgaaggtcggaccgagagcgcttgattcctgggggccccggggaagtctggtcaccgtatcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8190 JY8QFUQ01CQYQ6 No results +8191 JY8QFUQ01C4ME7 No results +8192 JY8QFUQ01C9SPS No results +8193 JY8QFUQ01CBYYT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8194 JY8QFUQ01CQXW9 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKKTL*FGDLF#YNFDYW out-of-frame - stop codons in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); ctctgggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatgGgtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaacattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8195 JY8QFUQ01C404O No results +8196 JY8QFUQ01DKGVY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 899 91.16 196/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARFGPLTRPDYW in-frame - tctggatcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8197 JY8QFUQ01BTYDV productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1072 99.09 217/219 nt 97.72 214/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [2.17.38.11] CARDFFIGGYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 42 of V-REGION: 'GT' (2 nucleotides at position 43 to 44 in the user submitted sequence), (cause frameshift); gcctctggattcaccGttcagtagGctatagcatgaactgggGTccggccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +8198 JY8QFUQ01CGQ8K No results +8199 JY8QFUQ01B9EGZ productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8200 JY8QFUQ01CAZ62 No results +8201 JY8QFUQ01AN1PQ unknown (see comment) Homsap IGHV3-11*01 F (see comment) 633 77.1 165/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AN1PQ ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (77,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8202 JY8QFUQ01C2YS7 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 904 89.33 201/225 nt 88.0 198/225 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 2 8 10 12 8.10.12 [2.17.38.11] CTITVRPDDYHDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 61 to 62 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift); gtctctggagtcactttcactaacgtgtggatgagttgggtccggcagGgctccagggaaAGggggccggagtgggttggccgtattaaaagggagactgacggggggacaatagactacgctgcacccgtgacagcaagattcaccatgtcaaaagatgattcCaaaaaacacactatatctgcaaatgaacaacctgaaaatggaggacacagccgtgtattactgtaccataacagtccgaccggatgattaccatgactactggggccagggaaccctggtgaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8203 JY8QFUQ01B81I7 unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 719 85.28 168/197 nt 84.77 167/197 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) tctgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaact +8204 JY8QFUQ01DASUZ productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 849 87.0 194/223 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD4-23*01 ORF 3 8 10 14 8.10.14 [1.17.38.11] CSRRSTLVTGYVFDKW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggaatcaactttcgtgatcatgccatgagctggttccgccaggttccagggaaggggctggagtgggtaggtttcattagaagttctcaatacggtggagatacagaatacgccgcgtctgtggaaggcagattcaccatctcaagagacgattccaaaagcatcgcctatttggatatgaatagcctgaaaatcgacgacacagccctatattactgttcccggaggtcgacgttggtgactggatacgtctttgacaagtggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8205 JY8QFUQ01A404T No results +8206 JY8QFUQ01C8KNM productive (see comment) Homsap IGHV3-30*01 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [2.17.37.11] CARGTMLRGVTKARYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 210 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8207 JY8QFUQ01DJCWQ unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P 101 95.45 21/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggattcactttcagtga +8208 JY8QFUQ01AHDAJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +8209 JY8QFUQ01DW4U2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactc +8210 JY8QFUQ01AY67B productive Homsap IGHV1-3*01 F 966 94.86 203/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARWNNDLDYW in-frame - tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagtaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8211 JY8QFUQ01BAELP unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F (see comment) 231 97.92 47/48 nt Homsap IGHD2-8*02 F 2 8 7 X 8.7.X [1.17.38.11] CARVVTTTILYWV#YYFDSW out-of-frame + stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); ctatggtgcgtccttcagtgattactcctgggcctggatccgccagTcccccagggaaggggctggagtggattggagagatcaatcatagtggaagcaccaactacaacccgtccctcaagagtcgaggcatcatatcaatagacatgtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacacggctgtatattactgtgcgagagtcgtcacgactacaattttatactgggtcctactactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +8212 JY8QFUQ01C1AVK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.16.38.11] CARGLDPGTNDYFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 49 of V-REGION: 2 nucleotides (from position 63 in the user submitted sequence), (cause frameshift) acctctggattcatcttcagtggctactggatgcactgggtccgccaagtcccagggaagggctgtgtgggtctcacgtgttaatcgcgatggaactaatacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaagactttctatcttcaaatgaacagtctgaaggtcgaggacacggctctatattattgtgcaagaggcctggaccctggcaccaacgactactttgactcctggggccagggaaccctggtcaccgtcgcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgatggtgtcgtggaactcag +8213 JY8QFUQ01CUVK8 unproductive Homsap IGHV3-48*02 F 881 90.23 194/215 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [0.17.38.11] CARGQNGYKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8214 JY8QFUQ01ACQTF unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 270 92.06 58/63 nt 8 X X 8.X.X [1.11.X.X] null + No rearrangement found ctctggattcaccttcagcagctatagaatgaactgggtccgccaggctccagggaagggctg +8215 JY8QFUQ01BSHY5 No results +8216 JY8QFUQ01CJ3C7 productive Homsap IGHV3-48*01 F 873 89.4 194/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8217 JY8QFUQ01B361P productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 982 94.52 207/219 nt 94.06 206/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaAaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8218 JY8QFUQ01A2SA0 productive Homsap IGHV4-4*07 F (see comment) 1021 97.22 210/216 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD4-11*01 ORF 2 10 7 13 10.7.13 [2.17.38.11] CARDFSNRGWYFDLW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01A2SA0 ; 8 AA in Homsap_IGHV4-4*07) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctctggtgactccatttccagtactagttattactggggctgggtccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8219 JY8QFUQ01DE3MC productive (see comment) Homsap IGHV3-9*01 F 901 90.41 198/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [2.17.38.11] CAKDGDSGWDYYDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); gcctctggattTaacctttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtAgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8220 JY8QFUQ01A1KJ6 No results +8221 JY8QFUQ01BNCWH unknown (see comment) Homsap IGHV3-48*01 F 968 94.04 205/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctctggtgggtccttcagtggttacttctggaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaacctcag +8222 JY8QFUQ01BFH58 No results +8223 JY8QFUQ01CTE1V productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8224 JY8QFUQ01CH1K2 No results +8225 JY8QFUQ01CS6YL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgGaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8226 JY8QFUQ01ADJZC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8227 JY8QFUQ01A48BS No results +8228 JY8QFUQ01BR1M6 No results +8229 JY8QFUQ01AVBV0 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 858 89.25 191/214 nt 88.32 189/214 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.16.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 77 of V-REGION: 'C' (1 nucleotides at position 132 to 132 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtggctccatgaggaattattactggagctggatccggcagtccccaggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaCccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8230 JY8QFUQ01BB5SC No results +8231 JY8QFUQ01B3K61 No results +8232 JY8QFUQ01CIAEG productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8233 JY8QFUQ01DNHOD unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1010 97.64 207/212 nt 96.7 205/212 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.37.11] CARLGSGG*SWL#YADYW out-of-frame - stop codons in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 108 in the user submitted sequence), (cause frameshift) tctggtggctccatcagtCagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaaccctccctcaagagtcgggtcaccatgtcagtggacacgtccaagaaccagttctccctgaagctgagctctctaaccgctgcggacacggccgtgtattactgtgcgagactagggtccggggggtagtcgtggttattacgctgactactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +8234 JY8QFUQ01C344R productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 865 88.58 194/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [2.17.38.11] CTRVGTFNWFGPW in-frame - gcctctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8235 JY8QFUQ01DNHYA productive Homsap IGHV3-7*01 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-2*01 F 2 8 8 9 8.8.9 [1.17.38.11] CATRSRSPANW in-frame + ctctggattcagttttagtacctattggatgagctgggtccgccaggctccagggaaggggctggaatgggtggccaccataaacgaggatggaagtgacagaacctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaaaaattcattgtatctacaaatgaatagcctgagaaccgacgacacggctcgatattactgtgcgacgcgtagtagaagtccggcgaactggggccagggaagcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8236 JY8QFUQ01BM618 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 807 85.45 188/220 nt 85.0 187/220 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); aatgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGgggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8237 JY8QFUQ01BNLHU productive Homsap IGHV1-24*01 F 988 96.24 205/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame - ggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8238 JY8QFUQ01A9A1W No results +8239 JY8QFUQ01CH781 No results +8240 JY8QFUQ01DL1LT productive (see comment) Homsap IGHV1-3*01 F 956 94.81 201/212 nt 94.34 200/212 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 7 9 8.7.9 [0.17.38.11] CARWNNDLDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 2 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8241 JY8QFUQ01CJOBK productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8242 JY8QFUQ01C5M80 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDDGGTH##LDVW out-of-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattcacatttcgaagttattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcggctgtaagtggtggtggcggcgccacaacctacgcggactccgtgaagggccggttcaccatctccagagacaatacacagaagatggtgttcctagaaatgagcagcctgagagtcgaagacacagccttatattattgtgcgcgagatgacggggggacacatgactttagatgtctggggccaggggacaatggtcaccgtctcttcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8243 JY8QFUQ01DI09E productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8244 JY8QFUQ01AE9OW No results +8245 JY8QFUQ01A8G0E productive (see comment) Homsap IGHV3-11*01 F 904 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.37.11] CARRLLSSGWPPHEWGFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 157 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaagggactggagtgggtctcatatattagcagtactggtggttccatatattacgcagactctgtgaagggccgcttcaccacctccagggacaacaccaaaactcaatgtctctgcaaatgaacagcctgagcgtcgacgacacgggcgtctattattgcgcgagaaggcttctcagtagtggatggccaccccacgagtggggcttctggggccagggagtccaggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +8246 JY8QFUQ01AF3ZS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8247 JY8QFUQ01CRDF7 unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CARRGRCG*#YWYFDLW out-of-frame + stop codons tctctagtgactccatcagcagtactaattactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatgtatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgagacgggggagatgcggataactactggtacttcgatctctggggccgtggcaccctggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +8248 JY8QFUQ01CGTZG No results +8249 JY8QFUQ01DHR8T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8250 JY8QFUQ01BX6XO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - tctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8251 JY8QFUQ01BWIHJ productive (see comment) Homsap IGHV3-7*01 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaaaCgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8252 JY8QFUQ01C2NGE productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + ctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8253 JY8QFUQ01DSYYV No results +8254 JY8QFUQ01AV27W productive Homsap IGHV3-30*15 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame + cctctggattcacctttagtagatattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttatatcatacgatggaagtagaagaatctacgcagactccgtgaagggccgattcaccatctccagagacacttccaagaacacggtgtatctgcaaatgagtagcctgagacctgaggacacggctgtgtattactgtgcgagagatgagctgccttgggatacaatagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +8255 JY8QFUQ01BGXD7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*02 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDRYPRSTAITAPDYW in-frame - ctctggattcccctttagcaactatgccatgacctgggtccgccaggctccaggggagggactggaatgggtctcaagtattagaggtagtggtgacaggacatcctacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagctgaacaacctgagagccgaggacagggccgaatattactgtgcaaaagatcgctaccctcggtcgacagctattacagcgcctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8256 JY8QFUQ01C82ML No results +8257 JY8QFUQ01CC5OR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8258 JY8QFUQ01B78ZT unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1007 96.74 208/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CAREDGFRQT##FDYW out-of-frame + stop codons tctctggtggctccatcagtagttactactggagctggatccggcagcccccaggaaagggactggagtggattgggtatatcttttacactgggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggttccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8259 JY8QFUQ01DIBAK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-48*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDMIIFGGALDNW in-frame + ctctggattcattttcagtaactataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagtcacatatactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggagcccttgacaactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8260 JY8QFUQ01BO2N3 productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'AG' (2 nucleotides at position 66 to 67 in the user submitted sequence), (cause frameshift); tggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtAGgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8261 JY8QFUQ01B1ZC8 No results +8262 JY8QFUQ01CVLIG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARPGGIAYCSGGSCYDPW in-frame + ctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcacccccaagatgggacgtggtcgtcgcatgcctggtccagggcttcttccccca +8263 JY8QFUQ01AZFTQ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtactaatacgggggggactagcacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattattgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +8264 JY8QFUQ01BKRE0 productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CASAPSDSSGYYFSYW in-frame + tggatacaccttcaccagttactatatgcactgggtccgacaggcccctggacaagggcttgagtggatgggaatgatcaaccctagtggcggaagcacaatctacgcacagaacttccagggcagagttgccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgctagcgccccctctgatagtagtggatactacttttcctactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8265 JY8QFUQ01AKLI2 No results +8266 JY8QFUQ01AKVGF unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 654 93.88 138/147 nt 93.2 137/147 nt 8 8 X 8.8.X [1.17.13.X] null - No rearrangement found in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 126 in the user submitted sequence), (cause frameshift) cctctggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgagaagtattatgtgggctctgtgaaggccgattcaccatctccagaga +8267 JY8QFUQ01CJFIZ productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD1-26*01 F 1 8 7 18 8.7.18 [2.17.38.11] CARGWAQQAGATFVGWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'GA' (2 nucleotides at position 80 to 81 in the user submitted sequence), (cause frameshift); gtctatggtgggtccttcagtggttacacctggaactggatccgccagcccccagggaaggggctggagtggattggggGAaaatcaatcatagtggcaggaccaactacaacccgtccctcaagagtcgagtcaccatatcaatagacacgaccaacaaccagttctccctgaagttgacctctgtgaccgccgcggacacggctgtatatttctgtgcgagaggttgggcccaacaagcgggagctacgtttgttggctggttcgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8268 JY8QFUQ01DD0HG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CANEVGYCSGG# out-of-frame + in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaGggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccgaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +8269 JY8QFUQ01C1K01 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 800 86.05 185/215 nt 85.58 184/215 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.37.11] CVRDSDSSGYARYDSMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 121 in the user submitted sequence), (cause frameshift) tctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgagggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccagccaaggccatcggtcttccccctggcgccctgctccaggagcacctccgagagcaccagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +8270 JY8QFUQ01CTZLW productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt 86.7 189/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [2.16.38.11] CAKSPLSVAGTRQNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gctctgacttgcacctttaatagctatgccatggcctgggtccgccaggctccagggaagggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8271 JY8QFUQ01AZFGT productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 768 84.58 181/214 nt 82.71 177/214 nt Homsap IGHJ1*01 F 170 80.77 42/52 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.16.37.11] CARPDGGNGWAAKYFQMW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 54 of V-REGION: 'AT' (2 nucleotides at position 73 to 74 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 76 of V-REGION: 'T' (1 nucleotides at position 134 to 134 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 2 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) ctctgggttctcgtttaatagttatggcatgacatggttccgccaggctccggggaggggctggagtgggtcATgcatctataactggaactgggggtaacgttttctacgcagacttcgtgcagggccggttTcaccatctccagagacaattccgacaatgttgtttctgcaaatgaacagcctgagagttgaggacacggccgtgtattactgtgcgagacctgacggaggcaatggctgggccgcaaagtactttcagatgtggggccagggcacccttctcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8272 JY8QFUQ01BWI99 No results +8273 JY8QFUQ01B0K72 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 89.77 193/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKINNDFGDYDWFDPW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactggGgggcaccgactccaaccCcctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaatcaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggggcttcttcccccag +8274 JY8QFUQ01B48EK unproductive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 843 87.27 192/220 nt 86.82 191/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 X 10.7.X [1.17.38.11] CARGVAGP#YFDSW out-of-frame + in FR3-IMGT at codon 103 of V-REGION: 'G' (1 nucleotides at position 217 to 217 in the user submitted sequence), (cause frameshift); ctctggtggctccgtcagcagtggtaattactactggaactggatccgccaacccccagggaagggactggagtggattggatatatctactatgctggggccaccaacgtcgccccctccctcaagaaccgagtcaccataacgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccgtatattaGctgtgcgaggggcgtggctggaccccctactttgactcctggggccagggaaatctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatcggaacgtggtcatcgctgcctggtccagggcttcttccccca +8275 JY8QFUQ01C008Z No results +8276 JY8QFUQ01CTBVM No results +8277 JY8QFUQ01CA62S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ6*04 F (see comment) 100 64.29 36/56 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CMNEFGYCSGGG in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacttttagcagccatatgatgacttgggtccgccaggctccagggaaggggctggaatgggtcgcaagtattcgtgccagtggtggtaggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgttgtatttgcaaatgtacagtctgagagtcgaggacacggccttatattattgtatgaacgaattcggatactgtagtggtgggggggccagggagcccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcatgcctggtccagggcttcttccccc +8278 JY8QFUQ01AX4R6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +8279 JY8QFUQ01BEYZ9 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 2 8 7 9 8.7.9 [1.17.38.11] CARDNYGDYWG in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccaggggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagccacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8280 JY8QFUQ01AEMOQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [0.17.38.11] CAKVVWSLWYFDLW in-frame + tacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8281 JY8QFUQ01CIX1D productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - tctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8282 JY8QFUQ01CM5UQ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARAGYCNNGVCYSSYFDFW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccggggaaggggctggtgtgggtctcacgtatgaatagtgatggcagtgacataaggtacgcggactccgtgaggggccgattcaccatctccagagacaacaccaagaacacgctgtatctacaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagcgggatattgtaataatggtgtatgctactccagttactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +8283 JY8QFUQ01CAD43 productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8284 JY8QFUQ01CQ9TR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8285 JY8QFUQ01AKSCK unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P (see comment) 307 73.11 87/119 nt 8 8 X 8.8.X [1.17.6.X] null - No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01AKSCK ; 7 AA in Homsap_IGHV3-69-1*01), and low V-REGION identity (73,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactacttccccgaaccggtgacggtgtcgtggaactcag +8286 JY8QFUQ01CCYFY productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8287 JY8QFUQ01C2LO1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8288 JY8QFUQ01B7E8G No results +8289 JY8QFUQ01B0DXX productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 952 92.34 205/222 nt 91.89 204/222 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.38.11] CTHLREEMSYEW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaAaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgtctggtccagggcttcttccccca +8290 JY8QFUQ01BK1TY productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8291 JY8QFUQ01B1Z8K No results +8292 JY8QFUQ01BJ6IJ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-15*01 F 2 8 8 21 8.8.21 [1.17.38.11] CARDSGMFCNSGSCYVYYGPDLW in-frame + ctctggattcttcttcagcagttttggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggcagtcacatcatatgatggaggtaataaattttatggagactcagcgaagggccgattcactatctccagagacaattccaaaaacacactgtatctgcaaatgaacagactgacaactgaggacacggctacttattactgtgcgagagattcggggatgttttgtaacagtggtagttgctacgtctattacggcccggacctctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8293 JY8QFUQ01AWUSJ productive (see comment) Homsap IGHV3-30*15 F 904 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 1 8 8 16 8.8.16 [1.17.37.11] CARNELPWDTREYYFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 105 in the user submitted sequence), (cause frameshift) ctccggattcacctttagtaaatattccatgaactgggtccgccaggctccaggcaaggggctcgagtgggtggcacttatatcatacgatggaagtagaaaatctacgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcatcgcctgcctggtccagggcttcttccc +8294 JY8QFUQ01AJDTG productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8295 JY8QFUQ01DEH5B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [2.17.38.11] CVRYDYSRLHRSNYFGPW in-frame - gtctctggattcaccttcatcagttatggcatgagttgggtccgccagtttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8296 JY8QFUQ01BVDDW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 17 8.8.17 [1.17.38.11] CANQWDSMVRGLITAPDYW in-frame - cctctggattcacctttaacacctatgccatgacctgggtccgtcagactccagggacggggctggaatgggtctcacttattagtggtagtggtgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacagttccaagaacacactatatttgcagatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaatcagtgggatagtatggttcggggacttattaccgctcccgactactggggccagggaaccctggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8297 JY8QFUQ01BN1G9 productive Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFNNW in-frame + Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttaacaactggggccagggaaccctggtcactgtgtcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8298 JY8QFUQ01BYSMX No results +8299 JY8QFUQ01BZXBW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacgaccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8300 JY8QFUQ01BTACU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CATDGVGSTVKLMVMGPFDFR in-frame + ctctggattcgtctttaacaactatgccatgggctgggtccgccaggctccagggaaggggttggagtgggtctcatctattagtactagtgggactaactcatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagcaagcgctttatctgcagatgaacagcctgagagccgaggacacggccgtttattactgtgcgacagatggagtagggtctactgtgaagttgatggttatgggcccttttgacttcaggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8301 JY8QFUQ01CS6JS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8302 JY8QFUQ01CU8I3 productive Homsap IGHV3-9*01 F 1054 98.17 215/219 nt Homsap IGHJ6*02 F 292 96.77 60/62 nt Homsap IGHD5-18*01 F 1 8 8 18 8.8.18 [2.17.38.11] CAKAGTARDTYHYYYGMDVW in-frame - gcctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagtgataggataggatatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatggacagtctgagagctgaggacacggccttgtattactgtgcaaaagcaggtacagccagagatacttaccactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +8303 JY8QFUQ01C3TUN productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARDRRPLREFDCW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 84 of V-REGION: 'C' (1 nucleotides at position 155 to 155 in the user submitted sequence), (cause frameshift); ctctggattcaccctctccagctatgctatgcactgggtccgccagtctcccggcaaggggctagagtgggtggcagctatttcatatgatggaagtaaaatatattacgcagactccgtgaggggccgcttctccatctccagagacagttccCaagaacactctgcatttgcaaatggacagcctgagacctgaggacacggctacatattactgtgcgagagatagacggccacttagggagtttgactgttggggccagggaaccccggtcgccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +8304 JY8QFUQ01A1DVA productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame - Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8305 JY8QFUQ01BE51J unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagcccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +8306 JY8QFUQ01A8H4Q No results +8307 JY8QFUQ01BG431 No results +8308 JY8QFUQ01CKCKN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD5-18*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKNGPRGYSYGYYYYAMDVW in-frame + ctctggactcacctttaccacctttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattagtgctagtggtggtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaagagcctgagagccgaggacacggccgtatattactgtgcgaaaaacggtccccgtggatacagctatggctactactactacgctatggacgtctggggccaagggaccacggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8309 JY8QFUQ01DAMYQ No results +8310 JY8QFUQ01C5XO0 No results +8311 JY8QFUQ01CXU11 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 678 79.44 170/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CXU11 ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (79,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactca +8312 JY8QFUQ01ASCDY No results +8313 JY8QFUQ01C6FF8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1075 100.0 216/216 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFD#PW out-of-frame + tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8314 JY8QFUQ01DP4MG productive (see comment) Homsap IGHV4-4*07 F (see comment) 566 73.95 159/215 nt 72.56 156/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (73,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); ctctggtacctccatcagcacttactattggagttcggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgcaaaactctaActacaaTcccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtaCtttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8315 JY8QFUQ01C8UR6 No results +8316 JY8QFUQ01DW754 productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 157 to 157 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataGccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaaGgaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8317 JY8QFUQ01CYT72 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +8318 JY8QFUQ01A2BAW productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8319 JY8QFUQ01BOWCG unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F (see comment) 603 75.12 163/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,12% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8320 JY8QFUQ01CRV27 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 774 83.87 182/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtaatggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctccaccaagggcccatcggtcttcccctggcacctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8321 JY8QFUQ01DPW7U productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8322 JY8QFUQ01AJTMK productive (see comment) Homsap IGHV3-11*01 F 535 92.06 116/126 nt 91.27 115/126 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 X 14 8.X.14 [1.5.27.11] CARDDSCSGGSCYEYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 44 of V-REGION: 92 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) cctctggattcagtttcagtgactactacatgagttggatccgccatctccagggacaacgccaagaagtcactgtttctgcaaatgagtagcctgagagccgaagacacggccgtgtactattgtgcgagagatgactcttgtagtggtggtagctgttacgaatactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8323 JY8QFUQ01AXQK9 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +8324 JY8QFUQ01CVK8G unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 131 52.11 99/190 nt 8 8 X 8.8.X [1.17.30.X] null - No rearrangement found stop codons tctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8325 JY8QFUQ01A5E27 productive (see comment) Homsap IGHV3-30*12 F, or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 822 87.38 187/214 nt 86.92 186/214 nt Homsap IGHJ4*02 F 181 85.42 41/48 nt Homsap IGHD5-24*01 ORF 3 8 7 13 8.7.13 [1.17.38.11] CASSRDGYNHGXRYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 65 of V-REGION: 3 nucleotides (from position 101 in the user submitted sequence), (do not cause frameshift) gtctggattcaccctcagctcctatggcatgcactgggtccgccgggctccaggcaaggggctagagtgggtggcgaatatgtttcatgatggaggctcttactatggaccctccgtgaggggccgattcaccatctccagagacaattcgaagaacacgctatttctacaaatgaacagcctgagagccgaggacacggctctatattactgtgcgagtagtagagatggctacaatcacggcttnagatactggggccagggaaccctggtcaccgtctcctctgcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +8326 JY8QFUQ01AV6V8 No results +8327 JY8QFUQ01C6R5U unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccaggggaacccctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8328 JY8QFUQ01DBYM0 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CGKQLGPIKG#DYW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcacctttagtaaccattggatgaactgggcccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatgccacaaattacgcagactccgtgaagggccggttcaccatctccagagacaactccatgaacacactgtatctgcaaatgaacagcctgggaaccgatgacacggccttatattactgtggaaagcaattggggcccataaaggggctgactactggggccaggggaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +8329 JY8QFUQ01C7I08 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 805 86.11 186/216 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD5-12*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDPGNYWGYYYDSW# out-of-frame + tctggattcacctttagtgattatgccttgagctgggtccgccagactcccgggaaggggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgagagatccgggaaattattggggatactattatgactcttggggtcctgggaacccctggtcgccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +8330 JY8QFUQ01C6F0T productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8331 JY8QFUQ01ANO1M productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - ctctgacttgcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8332 JY8QFUQ01B36PI productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 863 89.3 192/215 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame - cctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8333 JY8QFUQ01DRR7K unproductive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-22*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDGPPYLYGSHGNSFDQW# out-of-frame + stop codons in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtgggggcccagggaaccctagtcaccgtctcctcagcctccaccaaggggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgggaactcag +8334 JY8QFUQ01A3H9O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 940 93.06 201/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKGIVGDTFFDYW in-frame + tctggattcacctttagtaattatgccctgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggaatcagtagtagtggtgagatcccaaactacgcagactccgtgaagggccggttcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaaagggatagtgggagacactttctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8335 JY8QFUQ01AQY4E productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CIMDLVGRADYW in-frame + ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8336 JY8QFUQ01AJPR3 No results +8337 JY8QFUQ01A60HF productive Homsap IGHV3-7*01 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [2.17.38.11] CAREQSSRGYPLDYW in-frame - ggctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaggaactcactgtttctgcaaatgaacagcctgagaggcgacgacacggctgtctattactgtgcgagagaacaatcctcgaggggatacccacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8338 JY8QFUQ01CTQ1N productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 781 84.98 181/213 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARGEECRSGSCYSVWFDPW in-frame + Low V-REGION identity (84,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggtgggtccttaagtgactcctactgggcctggatccgccagcccccagggaagggcctggagtacattggggagatcagtcatgatggtagaaccatgttcaattggtccctcaagagtcgactcaccatctcagtagacacgtccaagaatcaattctccctgagattgacctctgtgaccgccgcggacacggctgtttattactgcgcgagaggcgaggaatgtcggagtggaagttgctactccgtttggttcgacccctggggccagggagcccaagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8339 JY8QFUQ01A0X8W productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARDSRHSASGSYSDYW in-frame - gcgtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8340 JY8QFUQ01CGIRF No results +8341 JY8QFUQ01B9VGM No results +8342 JY8QFUQ01ADMI2 No results +8343 JY8QFUQ01CT6QL productive Homsap IGHV3-48*02 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARVENYSDSGGSFDYW in-frame - gcctctggattcaccttcagtagctatagcatgaattgggtccgccaggctccagggaagggactggagtgggtttcatacattagtggaagtagtaataccatgtactacgcagactctgtgaagggccgattcaccatctccagagacaatgcccagaattcactacatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagtggaaaattactctgatagtggtggttcgtttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcattgcctgcctggtccagggcttcttccccca +8344 JY8QFUQ01BHMCF unknown (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F (see comment) 544 76.6 144/188 nt 8 8 X 8.8.X [1.17.28.X] null - No rearrangement found Low V-REGION identity (76,60% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttgatgattttgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaggatagtctatgcggactctgtgaagggccgattcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8345 JY8QFUQ01CUABV No results +8346 JY8QFUQ01DNRFJ No results +8347 JY8QFUQ01C2F53 productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +8348 JY8QFUQ01AY6HZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8349 JY8QFUQ01DWXJO productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 926 92.56 199/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - cctctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatcccctaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8350 JY8QFUQ01C1PQ2 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 900 90.78 197/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + gtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8351 JY8QFUQ01ARC40 productive Homsap IGHV4-39*03 F 929 91.36 201/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +8352 JY8QFUQ01DQFTR unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAQRSPER*LHIRRI*SV# out-of-frame - stop codons Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctaaatttgacttcagtgactatggcatgaactgggtccgccaggttccagggaaggggctggagtgggtctcctacataagtcgtctgagtcgccaaatatatgtcgctgacccagtgaagggccgattcaacatctccagagacaacgccaagaattcactgtatctgcaaatgaacaacttgcgggtcgaagacacggctgtgtatttttgtgcccaaagatcgcctgaacggtgactacacattcggcgcatttgatctgtgggggcccagggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +8353 JY8QFUQ01DBICC productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccttgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8354 JY8QFUQ01CAXM3 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 804 86.45 185/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame - ctctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8355 JY8QFUQ01CFMFT productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8356 JY8QFUQ01AU0NX productive Homsap IGHV4-61*02 F (see comment) 645 77.27 170/220 nt Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 10 7 13 10.7.13 [1.17.38.11] CATHSNGGARALDSW in-frame + Low V-REGION identity (77,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) ctctggtggccccgtcaacactgctggtctcttctggagctgggtccggcagcccgccgggaaacgacttgagtggatcggacatgtttctggtggaggggacaccacctacaatccctccctcgagagtcgggtcaccatgtcgttggattccctcaaaaacgagatctccctgacgttgacttccgtgaccgccgcagacacggccgtctactattgtgccactcattccaacggcggagcgagagcacttgactcctggggccagggggccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8357 JY8QFUQ01C7FZL unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 99 49.31 107/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctcaggattcatgttcaataactattggatgcattgggtccgccaagctccaggggagggcttggtgtgggtcgcacgtatcagcagtgatgggaacccgagtcaccgtctcttcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccg +8358 JY8QFUQ01CR090 productive Homsap IGHV3-48*01 F 814 86.57 187/216 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8359 JY8QFUQ01DQQAC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8360 JY8QFUQ01CZDBR unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDPGNYWGYYYDS## out-of-frame + ctctggattcacctttagcagttatgccatgagctgggtccgccagactccagggaaggggctggagtggatctcagaaattactggtgatggcgataacatatactacgcagactccgtgaagggccgtttcaccatctccagagacaattccaagaacactctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatccggggaactattgggggtactactatgactcttgggggcctgggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +8361 JY8QFUQ01CLKP9 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 817 85.59 190/222 nt 85.14 189/222 nt Homsap IGHJ3*01 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-16*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARTYTYRNAFDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 34 of V-REGION: 'ACC' (3 nucleotides at position 22 to 24 in the user submitted sequence), (do not cause frameshift); gtctttggtgactctctgagtACCagtagcagtttctactggggctgggtccgccaggccccagggaagggactggagtgggttgggactgtttattatagtgggagcgcccactacaatccgtccctcaagagtcgagtcgccatatccgtggacacggcccaaaaccaggtctccctgactttgaactctgtgaccgccgcagacgccgctgtctatttctgtgcgagaacttatacttatagaaatgcttttgacgtctggggccaggggacattggtcgctgtgtcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8362 JY8QFUQ01C4BMN unproductive Homsap IGHV4-61*03 F 152 66.25 53/80 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-10*01 F 3 X X X X.X.X [X.X.26.11] CATVRHLGERIFDF# out-of-frame + tctctggggccaccatgagtagtttctactggagctggctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctgggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +8363 JY8QFUQ01C0WTC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8364 JY8QFUQ01CO7OU No results +8365 JY8QFUQ01BFB0Q productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 845 88.37 190/215 nt 87.91 189/215 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 7 15 8.7.15 [1.17.38.11] CAKVYTGAWGDPNFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcagctttagcaactttgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtactttagcacccattatgccgactccgtgaagggccgcttcaccatctccagagacaatttcaggagcaccttatatctgcagatgaacaacctgagagccgacgacacggccatatattactgtgcgaaagtgtacaccggtgcctggggggatcctaattttgactcctggggccagggaaccctggtcaccgtctcctcagcattcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8366 JY8QFUQ01AKV8X unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 2 8 8 X 8.8.X [1.16.38.11] CANASPRITGN#YFYYYGMDVW out-of-frame - in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaagggctggagtgggtctcagccattagtggtantggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactgggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8367 JY8QFUQ01CVFKN productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggGtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8368 JY8QFUQ01CX9OH No results +8369 JY8QFUQ01DMWUQ No results +8370 JY8QFUQ01CQ80T productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8371 JY8QFUQ01B3J5C productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8372 JY8QFUQ01BQ9G8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD1-1*01 F 3 8 8 8 8.8.8 [1.17.38.11] CAVNWNLDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagcggctatgccatgagctgggtccgccaggctccagggaaggggctggactgggtctcatctattagttataatggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctccaaatgaacagcctgagagccgaggacacggccgtatattactgtgctgtgaactggaaccttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8373 JY8QFUQ01A31S4 productive Homsap IGHV4-39*03 F 929 91.36 201/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8374 JY8QFUQ01AUZHT unproductive (see comment) Homsap IGHV3-66*02 F 924 93.36 197/211 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [0.17.38.11] CVGDRQRDNYFAYW in-frame - stop codons tggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggctgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8375 JY8QFUQ01CQ4WI productive (see comment) Homsap IGHV1-3*01 F 849 88.79 190/214 nt 88.32 189/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggGggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8376 JY8QFUQ01CP0UW No results +8377 JY8QFUQ01AK05F unknown (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F (see comment) 281 65.54 97/148 nt 8 8 X 8.8.X [1.17.14.X] null - No rearrangement found Low V-REGION identity (65,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8378 JY8QFUQ01B23WP productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8379 JY8QFUQ01CZXHW unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 88 51.91 68/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +8380 JY8QFUQ01BFEGU productive (see comment) Homsap IGHV3-9*01 F 885 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD3-22*01 F 2 7 8 22 7.8.22 [1.17.37.11] CVRQAYYHDSSAYFFSRYWYFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) tctggattcactttgatgactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacgccagaagtccctgtttctgcaaattaaaagtctgagagttgaggacacggccttatattattgtgtgaggcaagcgtattaccatgatagcagtgcttacttcttctcccgctactggtacttcgatctctggggccgtggcaccccggtcactgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8381 JY8QFUQ01DHSAM No results +8382 JY8QFUQ01AIXJL productive (see comment) Homsap IGHV3-23*05 F 791 87.38 180/206 nt 86.41 178/206 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 7 7 10 7.7.10 [X.16.38.11] CAKRPPGTIDRW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 51 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) ttcacctttggcacctctgacatggcctgggtccgccaggttccaggggagggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8383 JY8QFUQ01CNCBL productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 1034 98.14 211/215 nt 97.67 210/215 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-2*02 F 2 8 7 15 8.7.15 [1.17.38.11] CARGVGVSWHTEYFQHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); cctctgggttcaccgtcagtagcGaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagaggggtcggcgtcagctggcatactgaatacttccagcactggggccagggcaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8384 JY8QFUQ01BN1A6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [2.17.38.11] CVRDSGPSGYARYESMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8385 JY8QFUQ01BJLQG productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*13 F 919 91.32 200/219 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [2.17.38.11] CARDDFYSSGNYGGFGMDVW in-frame - gcctctggattcaccttcagtcactatggtatacactgggtccgccaggctccaggcaaggggctagattgggtggcatttatatcatatgatggaagtaatgagttttacgcagactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagcccgaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8386 JY8QFUQ01CC9VV productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8387 JY8QFUQ01DP27V No results +8388 JY8QFUQ01BRM16 No results +8389 JY8QFUQ01C0NSG unproductive (see comment) Homsap IGHV3-21*04 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame - stop codons in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); ctctggattcgccttcagtacatatatcatgaattgggtccgctaggctccagggaaggggctggagtgggtctcatccattagAttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8390 JY8QFUQ01DRBJQ No results +8391 JY8QFUQ01CN5XI productive (see comment) Homsap IGHV3-9*01 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.16.38.11] CARGIAVAASHESTFDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 42 of V-REGION: 2 nucleotides (from position 38 in the user submitted sequence), (cause frameshift) ctctggattcacctttgatgattttgccatgcactggtcggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaggatagtctatgcggactctgtgaagggccgattcaccatctccagagacaacgcccagaactccctgtatctgcaaatgaacagtctgggtactgaggacacggccttgtattactgtgcaaggggtatagcagtggctgcctcccacgagtcgacttttgactactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8392 JY8QFUQ01AXL5M unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 896 89.91 196/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8393 JY8QFUQ01BK7CO unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 766 83.56 183/219 nt 82.19 180/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDLYGADDLW in-frame - stop codons Low V-REGION identity (83,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 50 of V-REGION: 'AGCTG' (5 nucleotides at position 64 to 68 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'AGTAAC' (6 nucleotides at position 94 to 99 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccgggggaagggAGCTGgtggctagggtctcactaatcattaAGTAACtggatggtaactgaaatagAccacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggtaacgtggtcatcgcctgcctggtccagggcttcttccccca +8394 JY8QFUQ01DS112 No results +8395 JY8QFUQ01CES1G No results +8396 JY8QFUQ01B6CNR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKDKWYYDSSGYQYYLDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacacatactactcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctggatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagacaaatggtactatgatagtagtggttatcaatactaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8397 JY8QFUQ01BBC0J unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8398 JY8QFUQ01CJIFK unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +8399 JY8QFUQ01BES39 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 750 83.64 179/214 nt 83.18 178/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctgatcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8400 JY8QFUQ01A42MA unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag +8401 JY8QFUQ01CN631 No results +8402 JY8QFUQ01DHS87 No results +8403 JY8QFUQ01AZOSQ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 896 90.37 197/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) aggcctctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8404 JY8QFUQ01COAJR No results +8405 JY8QFUQ01BKUNY productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 826 86.04 191/222 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [2.17.38.11] CVRHVRRFWFDPW in-frame - tctctaatgggctccatcagcggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8406 JY8QFUQ01B0V5N No results +8407 JY8QFUQ01A8N9K productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +8408 JY8QFUQ01DGZ15 productive Homsap IGHV3-48*02 F 864 88.94 193/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD6-6*01 F 1 8 8 20 8.8.20 [1.17.38.11] CARDDSRLWSSSFNHYFAMDVW in-frame + ctctggattcacctttagtgattatagaatgaattgggtccgccaggctccagggatggggctggaatgggttgcacacattagtaccagtggtagtagtatatactatgcagactctgtgaagggccgattcaccgtctccagagacgatgccaagaattcactttttctgcaaatggacagcctgagagacgacgacacggctgtatattactgtgcgagagacgattcacggctgtggagctcgtcatttaaccactatttcgctatggacgtctggggccaagggaccaccgtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8409 JY8QFUQ01BGUJA unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDRSGQAVGY## out-of-frame + in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggGggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaacccgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccagaaccggtgacggctgtcgtggaac +8410 JY8QFUQ01CG2UM productive Homsap IGHV3-7*03 F 845 88.37 190/215 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [0.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame + ctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +8411 JY8QFUQ01DUYGA productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccacaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8412 JY8QFUQ01AKPPR unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CVKDWGPNRQMWFGES#SG out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 62 of V-REGION: 'GCTGTTGCC' (9 nucleotides at position 92 to 100 in the user submitted sequence), (do not cause frameshift); ctctggattcacgttcagcagctatgccatgacctgggtccgccagactccagggaaggggctggagtgggtctcaactattcatggcggtGCTGTTGCCggtggcaccacagactacgcggtctccgcccagggtcgattcaccatctccagagacaattccaagagcacactgtatttgcaaatgagcgacctgagacccgaggacacggccctctatttctgtgtgaaagactggggccccaatcggcagatgtggttcggggagagtctctggggcccagggaactctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8413 JY8QFUQ01A4ER3 No results +8414 JY8QFUQ01AZS6M unproductive (see comment) Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKRRVGDTSDWY#YFEYW out-of-frame + stop codons ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc +8415 JY8QFUQ01DH35L productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 811 85.84 188/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8416 JY8QFUQ01B3HI3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 768 82.96 185/223 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [3.17.38.11] CARDDGGHMTLDVW in-frame - Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ccaatgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8417 JY8QFUQ01BNZ0M productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8418 JY8QFUQ01AS4EZ productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 609 96.92 126/130 nt 96.15 125/130 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 X 9 8.X.9 [1.3.31.11] CTREVGATDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 38 in the user submitted sequence), (do not cause frameshift) gtctggattcaccttcaggagctattggatgagctggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8419 JY8QFUQ01DFVGJ productive (see comment) Homsap IGHV2-5*02 F, or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F 923 86.53 212/245 nt 85.71 210/245 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 3 10 7 11 10.7.11 [9.17.38.11] CAHFGPQEHFDFW in-frame - Potentially, because of detected insertion/deletion in FR1-IMGT at codon 20 of V-REGION: 'C' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 28 of V-REGION: 'AT' (2 nucleotides at position 34 to 35 in the user submitted sequence), (cause frameshift); agaccctcCaccctgacctgcgacttctctgggATtcctcactcagcaccaatggaatgggtgtgggttggatccgccagaccccgggagaggccccagactggctcgctctcatttattgggatgatgataagcgataccggccatccctagagagtagactcaccatcaccaaggacatctccacaaaccaggtggtccttagaatgaccgacatgggccctgcagacacagccacatatttctgtgcacactttggaccacaggagcacttcgacttttggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8420 JY8QFUQ01BSEGS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 856 88.13 193/219 nt 87.21 191/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [2.17.38.11] CAKQKHSYGYYFDQW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); gcctctggattcacGctttaaaacacatgccatgagctgggtccgccaggctccaggaaAaggggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaaacatagttatggatactactttgaccagtggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8421 JY8QFUQ01CDYW8 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARLPNTIDSW in-frame + Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) ttctggatatagttttgccacctactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatgggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccgggtcaccatttcagccgacaagtccctcagtatcgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagactgcctaacactattgactcctggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8422 JY8QFUQ01CSIQ6 productive (see comment) Homsap IGHV3-11*01 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ6*02 F 112 64.52 40/62 nt Homsap IGHD2-2*01 F 3 8 7 20 8.7.20 [1.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggccagggggcacacggtcaccgtctcctagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8423 JY8QFUQ01CR487 productive Homsap IGHV4-61*01 F 1110 100.0 223/223 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [2.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame - tgtctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8424 JY8QFUQ01DH323 productive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame - ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacaacctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8425 JY8QFUQ01AT3GM productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame - ctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8426 JY8QFUQ01AO8X8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 720 81.57 177/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CAKVKGYGGNWFQPHFDRW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattctccttcgaggggtctgtcgtgacctgggtccgacaggctccagggaaggggctggagtgggtctcaggtatctacggtggtgatggtacatcattttacgcagacttcgcgaagggccgattcaccgtctccagagacaattccaaggacacggtctatctgcagatgaacggcctgagagtcgaagactcggcccgttattattgtgcgaaagtgaagggctacggcggcaattggttccagcctcactttgaccgctggggccagggcaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8427 JY8QFUQ01AUUMM No results +8428 JY8QFUQ01DCS74 productive Homsap IGHV3-48*01 F 810 85.78 187/218 nt Homsap IGHJ6*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 1 8 8 8 8.8.8 [1.17.38.11] CVRGAGLDVW in-frame + cctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaggggctggagtntgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctggacgtctggggccaagggaccacggtcgccgtctcctcagcctccaccaagggcccatcgggctcttccccctggcacctcctcccaagagcacctctgggggcacagcggccctgggctgcctggtcaggactacttcccccgaaccggtgacggtgtcgtggaactcag +8429 JY8QFUQ01BD3EO productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 677 92.41 146/158 nt 91.14 144/158 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-9*01 F 1 10 7 18 10.7.18 [1.17.17.11] CARLLRVYDWYSQRGYFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 71 of V-REGION: 62 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) ctccgatggctccatcagcactagtaattactactGggggctgggtccgccagcccccagggaaggggctggagtggattggaagtatatattatagtgggagcaccgactacagctcgtccctctgtgaccgccgcagacacggctatatattactgtgcgagactcttacgggtttatgactggtacagtcaaaggggttacttcgacacctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8430 JY8QFUQ01C3Z9T No results +8431 JY8QFUQ01BV5JV No results +8432 JY8QFUQ01CWNIA productive (see comment) Homsap IGHV3-66*02 F 948 93.93 201/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'CA' (2 nucleotides at position 56 to 57 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggCAaaggggctggagtgggtctcagttatttataccgGggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8433 JY8QFUQ01CKSAU productive Homsap IGHV4-4*01 F, or Homsap IGHV4-4*02 F or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 878 89.45 195/218 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 2 9 7 14 9.7.14 [1.17.38.11] CARDKDVTARGTFDMW in-frame + tctctggtgtctccatcagtagtaattactggtggatttgggtccgccagtccccaggggaggggctggagtggattggagaagtctatcatactgggaccacctattacaacccgtccctgaagagtcgagtcaccctgtcagtagacaagtccaggaatcagttctccctggagatgacttctgtgaccgccgcggacacggccgtgtatttctgtgcgagagataaagacgtgacagctcgtgggacctttgatatgtggggccaggggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +8434 JY8QFUQ01CLD43 productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8435 JY8QFUQ01C4LCW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKRWRASNGHFDYW in-frame - ctctggattcacctttagcagcttttccatggggtgggtccgccaggctccagggcggggactggagtgggtctcagccattgacggtcttactggtggtacatattacgcggactccgtgaggggccgattcaccatctccagagacgattccaagaacacactgtatctgcaaatgaatagcctgagagccgaggacacagccatatatcactgtgcgaagcggtggcgtgcttccaatggccactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8436 JY8QFUQ01AWG4X unproductive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 975 95.33 204/214 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [0.17.38.11] CVRGNAVVAASDD## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggaggcaccttcagcagtcatgctatcagctgggtgcgacaggcccctggacaagggcttgagtggatgggcgggatcatccctagttttggtacaccaaactacgcacagaagttccagggcagagtcacgatgaccgcggacgaatccacgagcacagcctacatggagctgagcagcctcagatctgaagacacggccgtgtattattgtgtgagaggtaacgcggtggtagctgccagcgacgactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8437 JY8QFUQ01BVWRE unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8438 JY8QFUQ01C9UFU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 2 8 8 9 8.8.9 [1.17.38.11] CARDNYGDYWG in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccaggggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8439 JY8QFUQ01BE1A6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - cctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8440 JY8QFUQ01AUWN1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-7*01 F 3 8 8 19 8.8.19 [2.17.38.11] CAKVFQVPGEHHFYYFGMNVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcatgtttaggaactatgccatgagttgggtccgccaggctccagggaaggGggctggagtgggtctcaactattagcaataatggaagccacacatactacgcagactccgtcaagggccggttcaccatctccagagacaattccaagaacacggtgtatatgcagatgaacaggctgagagtcgaggagacggccctgtactactgtgcgaaagtcttccaggtgcctggcgagcaccacttctactacttcggaatgaatgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8441 JY8QFUQ01BJJ53 productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame - cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8442 JY8QFUQ01C8JQA productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 962 92.41 207/224 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.38.11] CTHLREEMSYEW in-frame + cctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaaggcttcttccccc +8443 JY8QFUQ01DRH2R productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.18 194/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccaCtttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8444 JY8QFUQ01DK55H No results +8445 JY8QFUQ01BZ3H3 No results +8446 JY8QFUQ01DOTLO productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 836 89.81 185/206 nt 88.35 182/206 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 58 of V-REGION: 'A' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 9 nucleotides (from position 15 in the user submitted sequence), (do not cause frameshift) tctctggtgactcccacttctggagctggatccggcagcccccgggaaaagggctggagtggattggttatgtctataaAcagtgGggaccaccaactacaacccctccctcaggagtcgagtcaccatgtctatagacacgtccaagaagcagatctctctgaggttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactcctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8447 JY8QFUQ01AVINK unproductive Homsap IGHV3-48*03 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-8*02 F 3 8 8 X 8.8.X [1.17.38.11] CARESWWSGFM#WYDPW out-of-frame - in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcaCtttactatgcagactctgtgatgggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggctttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8448 JY8QFUQ01CKH2H productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttacCtggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgaaactcag +8449 JY8QFUQ01AFES7 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 917 90.18 202/224 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 2 8 10 15 8.10.15 [1.17.38.11] CTTDRRGLSIPPQFDFW in-frame - cctctggattcactttcagtgacgcctggatgagctgggtccgccagattccagggaaggggctggagtgggttggccgtataaaaaacaaagctatgggtgagacaacagacttcgctgcacccgtgagaggcagattcagtatctcaagagatgattcaaaaaatacactgtatctgcacatgagtggcctgaaaaccgaggacacagccgtctattattgtaccacagatcggcggggtttgtctataccacctcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8450 JY8QFUQ01BWRCS No results +8451 JY8QFUQ01B4AEC productive (see comment) Homsap IGHV4-61*02 F 816 85.91 189/220 nt 84.55 186/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 10 7 18 10.7.18 [1.17.37.11] CAREDYYGSGSYGRAWFDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 119 in the user submitted sequence), (cause frameshift) tctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggaTttgggcgcttctacagtcgtCgggggtgtcgactacaaccctccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagaggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8452 JY8QFUQ01DI5YM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame + ttctggattcacttttagcagtcatatgatgagttgggtccgccaggctccagggaagggactggaatgggtctcaagtattcgtgccagtggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgctgtatttgcaaatgtacagcctgagagtcgaggacacggccttatattactgtatgaacgaactcggatattgtagtggtgggggggtccagggagccctggtcaccgtctcctcaggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8453 JY8QFUQ01C9O87 productive Homsap IGHV3-64*02 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-9*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVRGRPMAGFHGILYDNW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttagtatcagtaattatggtattcactgggtccgccaggctccagggaggggactggaacttgtttcagctattaccaacaatgcgcatagtgtagtctatgtagactctgtgaagggcagattcatcatctccagagactattccaagaacacgttgtatcttcaaatgggcagactgagaccagaagacacggctgtgtactactgtgtcagagggcggcctatggctggctttcatggaatcctttatgacaactggggcctgggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +8454 JY8QFUQ01CO27Z productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1008 94.25 213/226 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGNYYDSGGLDYW in-frame - ctccggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcgaataactatcaagccagacgcatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtatattactgtgcaagagggggtaattactatgatagtggtggtcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8455 JY8QFUQ01AHMPT unproductive Homsap IGHV4-34*10 F 813 86.92 186/214 nt 85.51 183/214 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-23*01 ORF 3 8 7 X 8.7.X [1.16.38.11] CARNTNYGGNSGDYFDY## out-of-frame - in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AA' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) tgtctggtgagtccttcactaattactactggagctgGgatccgccagtcccccaggaAAagggtctggagtggcttggggagtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccacgggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8456 JY8QFUQ01A5MS2 productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8457 JY8QFUQ01C4BD8 productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.21 206/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatGggggcgtatctataccagtgggatcaccaactacaaccCcctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccacaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +8458 JY8QFUQ01AGDEN No results +8459 JY8QFUQ01A5MZO productive Homsap IGHV3-72*01 F 867 87.89 196/223 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 10 12 8.10.12 [1.17.38.11] CARDLGNGWGYDYW in-frame + ctctggattcatcttcagtgaccactatatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagagttgcatctaacacttacgccacagaatacgccgcgtctttcagaggcagattcgtcatctcaagagacaactcaaggaaatcattgtttctccaaatgaacagcctgagaaccgacgacacggccatgtattattgtgctagagatctgggcaatggctggggctacgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +8460 JY8QFUQ01BBON6 unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag +8461 JY8QFUQ01C8MB7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8462 JY8QFUQ01AFCLH productive Homsap IGHV4-61*01 F (see comment) 767 83.26 184/221 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8463 JY8QFUQ01B6W3L unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 125 56.52 65/115 nt 8 10 X 8.10.X [1.17.2.X] null + No rearrangement found ctctggattcagctttagttactattggatgagctgggtccgccaggctcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8464 JY8QFUQ01AQJU6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFD#PW out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgcctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8465 JY8QFUQ01DDXSG productive Homsap IGHV3-30*05 F, or Homsap IGHV3-30*06 F or Homsap IGHV3-30*12 F or Homsap IGHV3-30*13 F (see comment) 747 82.95 180/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-13*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAREADGQDLTTHLNWFDPW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtagttatagcatgcactgggtccgcctgtctccaggcaggggcctagagtgggtggcaggaatctcacacgatggcagtcagacagactacgcagcctccgtgaagggccggttcatcatttctagagacaattccaaagacacagtgtttctggaaatgaaaagcctgggcggagaagacacggctgtttactattgtgcgagagaagcagatgggcaagacctgacgacccacttgaactggttcgacccctggggccagggaatccaggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8466 JY8QFUQ01AXYTN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.16.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) agcctctggattcacctttaccacctccgccatggcctggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8467 JY8QFUQ01A3FZJ productive Homsap IGHV3-21*04 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +8468 JY8QFUQ01DEG6Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggactggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaaggcccatcggtctccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8469 JY8QFUQ01DNS6I unknown (see comment) Homsap IGHV3-7*02 F 972 94.47 205/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8470 JY8QFUQ01DR3V5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 952 94.37 201/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.16.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 92 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaagggctggtttggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8471 JY8QFUQ01BHB74 No results +8472 JY8QFUQ01A8IW5 No results +8473 JY8QFUQ01AVE0F productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKCKAPGKVDWFDPW in-frame - ctctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctggtaaggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8474 JY8QFUQ01CXU7L productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 899 91.16 196/215 nt 90.7 195/215 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); cttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattaCcttatcctgatggtactacatattatggagaccccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8475 JY8QFUQ01DU4E2 unproductive (see comment) Homsap IGHV3-74*03 F 846 88.02 191/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggcagccctggtccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8476 JY8QFUQ01C8ZZL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8477 JY8QFUQ01AZAYV productive Homsap IGHV3-11*01 F (see comment) 789 84.55 186/220 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARYRGSYYDYGGVDVW in-frame - Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release aacctctggcttcagattccgtgactactacatgacgtgggtccgccaggctccagggaagggtcttgagtggctttcctccatcagcagcggtagtaataccatccactactcagactcggtgaggggccgcttcaccatctccagggacaacaccaggaactcagtggatctgcaaatgaatagtctgagagccgaagacacggccgtctattattgtgcgaggtacagaggcagttactacgactatggcggtgtggacgtctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8478 JY8QFUQ01CDB52 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + ctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8479 JY8QFUQ01CTPGJ productive Homsap IGHV3-11*01 F 848 87.33 193/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [2.17.38.11] CVREVTGVWDWFDPW in-frame - cagcctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8480 JY8QFUQ01BYHGN productive (see comment) Homsap IGHV4-4*07 F 863 89.3 192/215 nt 87.91 189/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 7 9 8.7.9 [2.17.37.11] CARDSGDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'AC' (2 nucleotides at position 112 to 113 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 207 in the user submitted sequence), (cause frameshift) gtctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtccaaaccagtgggagcCccccactacaaACcccttccctcaagagtcgagtcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccattttttctgtgcgagagactccggggactttgactactggggcccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8481 JY8QFUQ01B97JU productive Homsap IGHV3-30*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAGDLTGVPYYYDSSGLKYW in-frame + cctctagattcaccttcagtagctataatatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcgcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +8482 JY8QFUQ01CJKNZ No results +8483 JY8QFUQ01BQERC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 8 8.8.8 [1.17.38.11] CAKRYSLDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift); ctctggattcacctttaagaactatgccttaaAactgggtccgccaggctccagggaaggggctgaagtgggtctccggaatcagtgctactggtgaaagcacacactacgcagactccgtaattggccggttcaccatctccagagacgattccaagaatacgttatatctgcaaatgaacagcctgagagccgaggacacggccgtatatttctgtgcgaaacgatattctcttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8484 JY8QFUQ01BT8WY productive (see comment) Homsap IGHV3-11*01 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 3 8 8 15 8.8.15 [1.17.38.11] CVRSYKLRGGLYYFDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'T' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); ctctggattcatcttcgatgactacttcatgacctggatccgccaggctccaTgggaaggggctggagtggatttctcacattgatggtagcggttctaccaggcactacgcagactctgtgaggggccgcttcaccatctccagggacaacgccaagaactccctttttctgcatatgaacagcctcagagtcgaggacacggccgtgttttactgtgtgagatcctacaaacttaggggaggtctttactactttgactcctggggccagggaagcctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8485 JY8QFUQ01BXALZ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame + tctctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8486 JY8QFUQ01CLJ0E unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CARAYSGPGPYYFD#IG out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattgggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccag +8487 JY8QFUQ01CRACO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame + ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8488 JY8QFUQ01AK13L productive Homsap IGHV3-48*01 F 1080 99.54 216/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASIFGVVPLGNYYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaaactca +8489 JY8QFUQ01AXBGY unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [1.17.38.11] CSNGYGDFPRR## out-of-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8490 JY8QFUQ01DQK9C No results +8491 JY8QFUQ01CRB0C productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8492 JY8QFUQ01BDA4R productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-3*01 F 2 7 8 13 7.8.13 [1.17.38.11] CAKRWRASNGHFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) cctctggattcacctttagcagctttccatggggtgggtccgccaggctccagggcggggactggagtgggtctcagccattgacggtcttactggtggtacatattacgcggactccgtgaggggccgattcaccatctccagagacgattccaagaacacactgtatctgcaaatgaatagcctgagagccgaggacacagccatatatcactgtgcgaagcggtggcgtgcttccaatggccactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8493 JY8QFUQ01BR7X8 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 934 91.44 203/222 nt 90.99 202/222 nt Homsap IGHJ1*01 F, or Homsap IGHJ4*03 F 93 69.05 29/42 nt 8 10 X 8.10.X [1.17.37.11] CTTESAY (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 161 in the user submitted sequence), (cause frameshift) ctctgcattcactttcagtaatgcctggatgacctgggtccgccaggctccagggaaggggctggagtggcttggccgtattaaaaggaaagttgatggtgagacaacagactacgctgcatccgtgaagggcagattcaccatctggagagatgactcaaaaacactctatatctgcaaatgaacagcctggaacccgaggacacagccgtatattattgtaccactgaatctgcctattgggccagggaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccgctgagcctctgcagcacccaggccatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8494 JY8QFUQ01AUX2R productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8495 JY8QFUQ01CIRSH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.02 200/215 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 7 7 11 7.7.11 [2.17.38.11] CAKEGNLGYFDDW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) gcctctggattcaccttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8496 JY8QFUQ01CHXOI productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcagg +8497 JY8QFUQ01CHSYW unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 687 80.37 172/214 nt 79.44 170/214 nt Homsap IGHJ2*01 F 148 75.47 40/53 nt Homsap IGHD1-26*01 F 1 8 7 X 8.7.X [1.17.38.11] CARLDGHFD#LW out-of-frame + Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 77 of V-REGION: 'GAA' (3 nucleotides at position 131 to 133 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 80 of V-REGION: 'T' (1 nucleotides at position 145 to 145 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcgggcttGAAtcgatctccagTagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgactctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8498 JY8QFUQ01C73TC No results +8499 JY8QFUQ01DDHD6 No results +8500 JY8QFUQ01A3RNK No results +8501 JY8QFUQ01CS0KM productive (see comment) Homsap IGHV4-61*02 F 816 85.91 189/220 nt 85.45 188/220 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD4-23*01 ORF 2 10 7 17 10.7.17 [1.17.37.11] CARGECGVNCPYYNWYQHW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 126 in the user submitted sequence), (cause frameshift) tgtctggtggctccatcagcagtgatgattactactggagctggatacggcagtccgccgggaagggactggagtggattgggcgaatttataaaagtggcgacacagtgtacaacccctccctcgggggcgagtcgccatgtcactggacacgtccaagaaccaattctccctgaggttgacttctgtgaccgccgaagacacggccgtctattactgtgcgaggggtgagtgcggtgtcaactgcccctactacaactggtaccaacactggggcccgggaacccgggtcaccgtcacgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8502 JY8QFUQ01COBOK No results +8503 JY8QFUQ01ASNTY unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPLGVG#FDNW out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8504 JY8QFUQ01ALJBN No results +8505 JY8QFUQ01DQBI6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKEQRGSGWSRSALDV## out-of-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaacggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8506 JY8QFUQ01DOPE8 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDGGSYNRMDLW in-frame + cgtctgggttcagtttcattgactatggcatacactgggtccgccaggctccaggcaaggggctggagtggatggcaattatatggtatgatgggaaaaataaatattatgaagagtccgtgaaggaccgattcaccgtctccagagacaattccaagaacacggtgtatttggaagtgaatagtctgagagtcgacgacacggctgtgtattactgtgcgagagacggtgggagctacaacaggatggacctttggggccagggaaccctggtcaccgtctcgtcagcatccccggaccagccccaagggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8507 JY8QFUQ01DUIBU productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 823 87.04 188/216 nt 86.11 186/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); gtctctggggactccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacacCtgggagtaCccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8508 JY8QFUQ01CO29A productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-16*02 F 2 8 7 19 8.7.19 [1.17.38.11] CARSSDYLWGSYRYPYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 71 of V-REGION: 'A' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagttacttctggagttggatccggcagcccccagggaagggactggagtggattggatatgtctattacagtggaagtaccaagtataatccttccctAcgaaagtcgagtcaccatatcattagacacgcccaacaaccagttctccctgagcctgacctatgtcaccgctgcggacacggccatatactactgtgcgagaagctctgattacctttgggggagttatcgttatccctactacttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8509 JY8QFUQ01C5AY2 No results +8510 JY8QFUQ01DRE2B productive Homsap IGHV3-30*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDELPWDTIEYYFDYW in-frame + ctctggattcaccttcaatacctattctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8511 JY8QFUQ01AEZCS productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 613 97.67 126/129 nt 96.9 125/129 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 X 10 8.X.10 [1.3.31.11] CSNGYGDFPRRW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 37 in the user submitted sequence), (do not cause frameshift) tctggattcaccttcaggagctattggatgagctggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +8512 JY8QFUQ01AI4NA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKAGYSSARTHMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagcaattttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttgtgagtggtagtggcgatagaacagactacgcagactccgtgaagggccggttcactatctccagagacaattccaagagtacactattcctgcaaatgcacagcctgagagtcgaggacacggccgtatattactgtgcgaaagctggatatagtagtgcgcgaacccacatggacgtctggggccaaggggtcgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8513 JY8QFUQ01BHJ2H productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8514 JY8QFUQ01CCCWM productive (see comment) Homsap IGHV3-30-3*01 F, or Homsap IGHV3-30-3*02 F (see comment) 403 78.79 104/132 nt 78.03 103/132 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 X 6 18 X.6.18 [X.X.38.11] CARDDFYSSGNYGGFGMDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (78,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtcactatgactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaAatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8515 JY8QFUQ01A5A7Q unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtctcctcagatccccgaccagccccaaggtcttcccgctgagcctcgacagnaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8516 JY8QFUQ01CWX10 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8517 JY8QFUQ01B6IM7 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDQRSGDA#EAFDIW out-of-frame + stop codons in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtcgctatagcatgaactGgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaaggtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +8518 JY8QFUQ01C3F50 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame + cctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8519 JY8QFUQ01BHRZG unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 115 53.57 75/140 nt 10 7 X 10.7.X [1.17.11.X] null - No rearrangement found stop codons ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8520 JY8QFUQ01DROPW unproductive Homsap IGHV3-11*01 F 980 95.35 205/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [0.17.38.11] CAKDPGGKVGATD#DHW out-of-frame - ctgggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccagggtcaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgaaagatccggggggaaaagtgggagctacggacttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8521 JY8QFUQ01DAHPO unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYFGTL#DYW out-of-frame + stop codons gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttggaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8522 JY8QFUQ01BHA2F productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 808 88.73 181/204 nt 88.24 180/204 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 3 8 8 11 8.8.11 [2.17.33.11] CATEKPGNEFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 15 nucleotides (from position 157 in the user submitted sequence), (do not cause frameshift) gcgtctggattcaccctcagttcctatgtcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagtcattggatttaatggacgcagcgagtattatgcagactccgtgaagggccgattcaccatctccagagacaattctctgcaaatgaacaatctgagagtcgaggacacggctgtctattactgtgcgactgagaaacccggcaacgaatttgattactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8523 JY8QFUQ01B9IA6 No results +8524 JY8QFUQ01BZ5ME productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 814 86.57 187/216 nt 85.65 185/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 7 7 9 7.7.9 [1.17.38.11] CTGLTYPDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 28 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 81 in the user submitted sequence), (cause frameshift) cgtctggatttaccttcagtaagttctgatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtataatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8525 JY8QFUQ01CUA2E productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8526 JY8QFUQ01C3FER No results +8527 JY8QFUQ01CI5PE No results +8528 JY8QFUQ01B7B1B productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8529 JY8QFUQ01B4HQ1 No results +8530 JY8QFUQ01DPZ3N No results +8531 JY8QFUQ01BK4SM productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8532 JY8QFUQ01C4FS7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 974 93.67 207/221 nt 93.21 206/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); cagcctctggaGttcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8533 JY8QFUQ01BGXQQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagaaccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8534 JY8QFUQ01BEWPJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame - ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8535 JY8QFUQ01B47SE No results +8536 JY8QFUQ01BNHM6 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 968 94.04 205/218 nt 92.66 202/218 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 7 8 10 7.8.10 [2.17.38.11] CAREVSDALDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 26 in the user submitted sequence), (cause frameshift) gcctctggattcatctttgatgatttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaaAttggaatggtggtaaaacaggttatgcagactctgtgaGggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctagtccagggcttcttccccca +8537 JY8QFUQ01BMU57 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 489 82.98 117/141 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (82,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag +8538 JY8QFUQ01CRX55 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8539 JY8QFUQ01BC4GZ unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F 449 91.51 97/106 nt 8 8 X 8.8.X [1.17.1.X] null + No rearrangement found tctggattcagtttcagtgactactacatgagttggatccgccaggctccagggagggggctggagtgggtttcatacattagtaggagtagtactgacatatact +8540 JY8QFUQ01BBDEH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 828 87.1 189/217 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD3-16*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASLNTHAGPGAERSAFDVW in-frame + ctctggattcatcttcagtaactatagaatgaactgggtccgtcaggctccagggaaggggctcgagtgggtctcgtccatcaccagttccagtagttacatctactatgcagactcggtgacgggccgattcaccatctccagagacaactccaaggggtcactctatctgcacatgaacgaccttagggccgaagacacggctgtctattactgtgcgagcctaaacacgcacgcgggaccgggagccgagaggtctgcttttgatgtctggggccgagggacaagggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +8541 JY8QFUQ01C4KK6 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 701 80.93 174/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [1.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame + Low V-REGION identity (80,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8542 JY8QFUQ01AUFGY No results +8543 JY8QFUQ01CQ8R1 No results +8544 JY8QFUQ01CXCFY unproductive Homsap IGHV3-74*03 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [2.17.38.11] CAISSGFTRR#YW out-of-frame - gcctctggattcaccttcagtcgctactggatgcactgggtccgccaagctccagggaagggcctggtgtgggtctcacgtattaaaagtgatgggattagcacaacgtacgcggactctgtgaagggccgattcaccatttccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8545 JY8QFUQ01DJCJZ No results +8546 JY8QFUQ01B2JOM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 943 93.9 200/213 nt 92.96 198/213 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 7 7 11 7.7.11 [1.17.38.11] CAKEGNLGYFDDW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 3 nucleotides (from position 81 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8547 JY8QFUQ01A63Q1 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8548 JY8QFUQ01B6C0L productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8549 JY8QFUQ01AQAA0 No results +8550 JY8QFUQ01BD2IQ productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYYYYDTNGDYW in-frame + tctggatttacctttacaaattattggatgagctgggtccgccaggctccagggaggggcgtggagtgggtggccagcgtaaaacaagatggaggtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggtcctactattattatgatactaatggcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct +8551 JY8QFUQ01DWJC4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8552 JY8QFUQ01CIHIM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8553 JY8QFUQ01A9P0G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8554 JY8QFUQ01CQWF7 unknown (see comment) Homsap IGHV3-74*03 F 129 55.3 73/132 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +8555 JY8QFUQ01A12KV productive Homsap IGHV3-48*01 F 815 86.24 188/218 nt Homsap IGHJ6*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 1 8 8 8 8.8.8 [1.17.38.11] CVRGAGLDVW in-frame + cctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaggggctggagtgtgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctggacgtctggggccaagggaccacggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +8556 JY8QFUQ01DN4IN productive (see comment) Homsap IGHV3-7*02 F 940 93.06 201/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'A' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'CT' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); tctacattcacgtttagtcggtattggatgagctgggtAccgccaggctccaggggaagggcCTgggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8557 JY8QFUQ01DCJWT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 782 86.89 179/206 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 5 8 10 5.8.10 [X.17.38.11] CSKDTFGREDYW in-frame + acttcaatggctttaatatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +8558 JY8QFUQ01AIBQ6 productive (see comment) Homsap IGHV3-72*01 F 961 92.79 206/222 nt 92.34 205/222 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD7-27*01 F 1 8 10 10 8.10.10 [1.16.38.11] CVRDPFSSRGHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcatcctcagtgactaccacatggagtgggtccgccaggctccagggaaggggctggagtggttggccgtagtagaaagaaagctaatagttacagtacagaatatgccgcgtctgtgaaaggcagattctccatttcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaatcgacgacacggccgtgtattattgtgtcagagaccccttctcaagtcggggccactggggccagggaaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt +8559 JY8QFUQ01ACH9Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 8 21 8.8.21 [1.17.38.11] CARVMREHYYGAGNYPWGGMEVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcacctttaacaactatgccatgacctgggtccgccaggctccggggaaggggctggagtgggtctcagctatcagtggcagtggcggtaccacttactacgcagactccgtgcagggccgcttcaccatttccagagacaatcacgaaaacaccctgtatctggaaatgagtagcctgagagccgaggacgcggccgtctattactgtgcgagagtgatgagggaacattattatggagcggggaattatccctgggggggaatggaagtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8560 JY8QFUQ01BGUSV No results +8561 JY8QFUQ01AGPNS productive (see comment) Homsap IGHV4-61*01 F (see comment) 758 82.81 183/221 nt 82.35 182/221 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 101 of V-REGION: 'C' (1 nucleotides at position 210 to 210 in the user submitted sequence), (cause frameshift); tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggttgaacgatgtgaccgctgcggacacggccCatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8562 JY8QFUQ01BVHQU unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.16.38.11] CYKRQSVGGT#YW out-of-frame + in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) cctccggattcacctttagtagttactggatgcactgggtccgccaaactccagggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaAgctacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgttacaagagacagtcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctccagcatccccgaccagcccaaggtcttcccggctgagcctcgacagcacccccgcaagatcgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8563 JY8QFUQ01ATXAK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8564 JY8QFUQ01B7VL5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8565 JY8QFUQ01BO056 No results +8566 JY8QFUQ01AU4V8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - tctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8567 JY8QFUQ01B6VH0 unproductive Homsap IGHV3-72*01 F 1074 98.21 219/223 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYD#PG out-of-frame + ctctggattaaccctcagtgaccactacatggactgggcccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8568 JY8QFUQ01BLIES No results +8569 JY8QFUQ01BBQWA No results +8570 JY8QFUQ01CCVT3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 875 88.69 196/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - cagcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8571 JY8QFUQ01BBNGZ productive Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARDPRVICSGGSCRSSAMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaacccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagaccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +8572 JY8QFUQ01B6YCL No results +8573 JY8QFUQ01B6L7M No results +8574 JY8QFUQ01BT7ZV No results +8575 JY8QFUQ01CK7J8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8576 JY8QFUQ01BN6KV unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F or Homsap IGHV7-81*01 ORF 143 59.43 63/106 nt 8 8 X 8.8.X [0.17.2.X] null - No rearrangement found cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +8577 JY8QFUQ01BLH08 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 870 88.64 195/220 nt 88.18 194/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); agcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtGgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8578 JY8QFUQ01CPDIO No results +8579 JY8QFUQ01B1JQ7 unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 714 85.2 167/196 nt 84.69 166/196 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) ctgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8580 JY8QFUQ01DNMX7 productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame - ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8581 JY8QFUQ01DQA69 No results +8582 JY8QFUQ01DLG7A unproductive Homsap IGHV3-7*01 F 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ4*03 F (see comment) 87 64.58 31/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [2.17.38.11] CARATNADV## out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaGgggggtactggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaccataaatcacgatggaagtcaaatttactatatggaccttgtgaagggccggttcaccatctccagagacaacgccgagacctcactctatttgcaaatgaacaccctgagagccgaagacacggctgtctattactgtgcgagggcgactaatgccgacgtctgggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8583 JY8QFUQ01DKDHQ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 930 92.99 199/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARRLNNYDSGEYAMDVW in-frame + tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8584 JY8QFUQ01CL2R1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8585 JY8QFUQ01AIIKB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggaacacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8586 JY8QFUQ01BBKAE No results +8587 JY8QFUQ01BXLBK productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 653 77.52 169/218 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD3-3*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIIREGLDRW in-frame + Low V-REGION identity (77,52% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) tgtctggtggttctactcgcactaaccattggtggaattgggtccgccagacccccgacaagggactggagtggattggagaagtctataagagtggacagaccaactacaacccgtcactccagagtcgcgttgacctcttcattgacaactccaggaatcagatctccctaaatatgagagatgtgaccgccgcggacacggccgtctattactgcgcgagagaagacattattcgggagggccttgaccgctggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8588 JY8QFUQ01BTLBP No results +8589 JY8QFUQ01CA6DO productive Homsap IGHV3-7*03 F 958 93.98 203/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-3*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKQTIFDYYYYGLDVW in-frame - tctggattcaccttcaggagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgacaaattctatgtggactctgtgaagggccgattcaccatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctggggccaagggaccacggtcaccgtcccctcagcatccccgacagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8590 JY8QFUQ01CLUBR productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + ctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8591 JY8QFUQ01DVSZR unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtgga +8592 JY8QFUQ01AJF0Q No results +8593 JY8QFUQ01C1XQ4 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8594 JY8QFUQ01BD9RX No results +8595 JY8QFUQ01BZRJN productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 883 89.5 196/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARKRVPGGTFYGDYW in-frame - gcctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgcctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8596 JY8QFUQ01ACLU1 productive (see comment) Homsap IGHV3-7*01 F 1022 96.79 211/218 nt 96.33 210/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGcctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8597 JY8QFUQ01A0TP4 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 464 67.89 148/218 nt 66.97 146/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (67,89% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'TG' (2 nucleotides at position 37 to 38 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); tgtctggattcacatttagaagctattccatgaattTGgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8598 JY8QFUQ01AI4L5 unproductive Homsap IGHV4-61*02 F 960 93.18 205/220 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD2-2*01 F 3 10 7 X 10.7.X [1.17.38.11] CARVVRCTTTGCSRVGWFD#PG out-of-frame + ctctggtggctccatcagcagtgatgattactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctcttccagtgggaacaccaactacaacccctccctcaggagtcgagtcaacatttcactagacatgtccaagacccagttctccctggagctgacctctgtgagcgccgcagacacggccgtgtattactgtgcgagggtcgttcgttgtactacgaccggctgctcaagggtaggatggttcgacccctggggccagggaacccgtggtaaccgtctcctcagcatcccccgaccagccccaaggctcttcccgntgagcctcgacagcaccccccaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccccc +8599 JY8QFUQ01BPJGG productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAKDFYYGCDYW in-frame + ctctggattcaacttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagtcattgcatacaatggaggaaatatatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaaggataccctgtacttgcacatgaccagtctgagacctgatgacacggccatgtattactgtgcgaaagacttttattatggttgcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8600 JY8QFUQ01CFLWN productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8601 JY8QFUQ01BM2HZ productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8602 JY8QFUQ01AWMLK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8603 JY8QFUQ01CHDAZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8604 JY8QFUQ01AMJQ0 No results +8605 JY8QFUQ01A4XAG unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARKRVPGGTFYG#DYW out-of-frame + cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatgggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +8606 JY8QFUQ01CQJ2P No results +8607 JY8QFUQ01C4BYC unproductive Homsap IGHV3-11*01 F 904 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.37.11] CARRLLSSGWPPHEWGF# out-of-frame + in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 157 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaagggactggagtgggtctcatatattagcagtactggtggttccatatattacgcagactctgtgaagggccgcttcaccacctccagggacaacaccaaaactcaatgtctctgcaaatgaacagcctgagcgtcgacgacacgggcgtctattattgcgcgagaaggcttctcagtagtggatggccaccccacgagtggggcttctgggccagggagtccaggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttc +8608 JY8QFUQ01CKSKF No results +8609 JY8QFUQ01BTX1Y productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 701 80.93 174/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [1.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame - Low V-REGION identity (80,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8610 JY8QFUQ01AGROF productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 932 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8611 JY8QFUQ01B4W9M No results +8612 JY8QFUQ01A544D No results +8613 JY8QFUQ01CN6MQ productive Homsap IGHV2-26*01 F 1080 93.85 229/244 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 10 7 20 10.7.20 [9.17.38.11] CARSPSHYSDSFGSYLNKFDYW in-frame + gaccctcacgctgacctgcaccgtctctgggttcttactcagcagtggtaagatgggtgtgagctggatccgtcagcccccagggaaggccctggagtggcttgcacacattttttcgaatggcgataaatcctacaacacatctctgaggagcaggctcaccatctccaaggacacccccaaaagccaggtggtccttaccgtgaccaacgtggaccctgcggacacagccacttattattgtgcacgttctccgtcgcattactcggatagttttggttcttacctcaacaaatttgactactggggtcagggaaccctggtcgccgtctcctcagcctccaccaaggggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccagaaccggtgacggtcgtcgtggaactcag +8614 JY8QFUQ01AZUML productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + ctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgctctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +8615 JY8QFUQ01AO8BO No results +8616 JY8QFUQ01CK9BK No results +8617 JY8QFUQ01C6JWN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1090 100.0 219/219 nt 99.09 217/219 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [2.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); gcctctggattcaccGtttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcGtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8618 JY8QFUQ01CLEXQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8619 JY8QFUQ01C1E0N No results +8620 JY8QFUQ01CJWU5 productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactca +8621 JY8QFUQ01AGAXJ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [2.17.38.11] CAKEGNLGYFDD## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) agcctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagg +8622 JY8QFUQ01AZU09 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 824 86.7 189/218 nt 86.24 188/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 101 of V-REGION: 'C' (1 nucleotides at position 209 to 209 in the user submitted sequence), (cause frameshift); cgtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtCatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8623 JY8QFUQ01C0MJD productive Homsap IGHV3-30*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAGDLTGVPYYYDSSGLKYW in-frame + ctctagattcaccttcagtagctataatatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +8624 JY8QFUQ01C4132 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 901 90.41 198/219 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [2.17.38.11] CARADDYGDYPEFW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gcctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgcttagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8625 JY8QFUQ01DJGCJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame + ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8626 JY8QFUQ01CBTTJ unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F (see comment) 624 80.0 156/195 nt 8 7 X 8.7.X [1.17.31.X] null - No rearrangement found Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8627 JY8QFUQ01DGCCW productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.17.38.11] CARGEMTAEYYFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacaCgcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8628 JY8QFUQ01A3MT9 productive (see comment) Homsap IGHV4-61*02 F 871 88.29 196/222 nt 87.39 194/222 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [2.17.38.11] CAREHSRTMGGARELDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'A' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); gtctctggtggccccatcagcagcagcacttactactggacttgGgatccggcaggccgccggggagggactggagtggatcggacgtgtttatActtagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8629 JY8QFUQ01AMRYH No results +8630 JY8QFUQ01B5CO0 unproductive Homsap IGHV3-72*01 F 889 89.19 198/222 nt 88.74 197/222 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-19*01 F 3 8 10 X 8.10.X [1.16.38.11] CARDLGNGWGYDY# out-of-frame + in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggcttcatcttcagtgaccactatatggactgggtccgccaggctccagggaaggggctggagtggttggccgtactagagttgcatctaacacttacgccacagaatacgccgcgtctttcaaaggcagattcgtcatctcaagagacaattcaaggaactcattgtttctccaaatgaacagcctgaaaaccgacgacacggccatgtattattgtgctagagatctgggcaatggctggggctatgactattgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +8631 JY8QFUQ01A7CTP No results +8632 JY8QFUQ01BX0J5 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 985 93.33 210/225 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 10 9 19 10.9.19 [1.17.38.11] CARGSSRGGNSDGVYYELDYW in-frame - tccggggacagtgtctctaccacccgtgctgcttggaactggatcaggcagtccccatcgggaggccttgagtggctgggaaggacatactacaggtccaagtggcttaatgattatgcagtgtctgtgaaaagtcgaattaccatcaatccagacacatccaagaaccagttttccctgcagttgaaatctgtcattcccgaggacacggctgtttattactgtgcaagaggttccagtcgcggggggaattctgatggggtctactatgaacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +8633 JY8QFUQ01BVKMY unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P 182 60.0 78/130 nt 8 6 X 8.6.X [1.17.11.X] null - No rearrangement found stop codons ctctggattcatcttcagtgactactacatgacctggatccgccaggctccaaggtcttcccgctgagcctcgacagcaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +8634 JY8QFUQ01CMONL unproductive Homsap IGHV3-7*01 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSDFYSTGH## out-of-frame - in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); tctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatgGgaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8635 JY8QFUQ01AH1M8 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.37.11] CVRRGMVAGRYDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 101 of V-REGION: 2 nucleotides (from position 207 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8636 JY8QFUQ01A3KYL productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8637 JY8QFUQ01C8ANE unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDYL# out-of-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactacctgggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtctcccctggcaccctctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8638 JY8QFUQ01CMIII productive Homsap IGHV1-2*02 F 1020 97.66 209/214 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [0.17.38.11] CAREHGSGTYSEYFQDW in-frame + tggatacgccttcaccggctactatatgcactgggtgcgacaggcccctggacaagggcttgagtggatggggtggatcaaccctaatagtggtggcacaaactatgcacagaagtttcagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggacctgagcaggctgacatctgacgacacggccgtgtattactgtgcgagagaacatggttcggggacttattctgaatatttccaggattggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8639 JY8QFUQ01BT0OK productive (see comment) Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 740 81.82 180/220 nt 81.36 179/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARVWVAGSRDENFDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); tctcgggtgcttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaaggGgcctagagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgccctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +8640 JY8QFUQ01CK2XZ productive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8641 JY8QFUQ01AGSH3 productive Homsap IGHV3-9*01 F 922 92.13 199/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - tctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8642 JY8QFUQ01CB4J1 No results +8643 JY8QFUQ01DJPPU productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-3*01 F 1 8 8 20 8.8.20 [0.17.38.11] CARDHRSGALEWSHHYHGMDVW in-frame - tggttacatcttcacccactatggtatcaactgggtgcgccaggcccctggacaagggcttgagtggatgggatggatcagcgcctacagtggtaacacaaagtatgcacagaaggtccagggcagagtcaccatgaccacagacacttccacgagtacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagatcacagaagcggggctttggagtggtctcaccactaccacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8644 JY8QFUQ01B3B9F productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 796 85.65 185/216 nt 85.19 184/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSGPSGYARYESMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); tctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggcgtggaagGtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8645 JY8QFUQ01B7E59 No results +8646 JY8QFUQ01DFN6M No results +8647 JY8QFUQ01CXRCB productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8648 JY8QFUQ01C4N1G unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 116 54.14 72/133 nt 8 8 X 8.8.X [1.17.9.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +8649 JY8QFUQ01B37IT productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + gtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +8650 JY8QFUQ01CMV96 No results +8651 JY8QFUQ01CE9LJ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 103 52.99 71/134 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8652 JY8QFUQ01A8WS2 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1060 100.0 213/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - tctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8653 JY8QFUQ01CI6C5 productive Homsap IGHV2-5*01 F 998 90.5 219/242 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 7 14 10.7.14 [8.17.38.11] CVQSHYYDNSGYFVSW in-frame + ccctcacgctgacctgcgacttctctgggttctcactcaccactagtggagtgggtgtggcctggatccgtcagcccccaggaaaggccctggagtggcttgcactcatttactggaacaatgatcagcgctatagcccatctctgaagaacaggctcaccatcagtcaggacagctccaaaaatcaggtcgtccttacagtgaccaatatggaccctgtggattccgccacatacttctgtgtccaaagtcactactatgataatagtggttactttgtttcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8654 JY8QFUQ01BI6RT productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 777 85.05 182/214 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARERGSGPPTGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaagaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8655 JY8QFUQ01B8C9Z unknown (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*03 F or Homsap IGHV4-59*07 F (see comment) 458 67.91 146/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (67,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8656 JY8QFUQ01BUW74 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8657 JY8QFUQ01C2LSU No results +8658 JY8QFUQ01CTDZI unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1014 95.91 211/220 nt 95.45 210/220 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [2.16.38.11] CVRGDYGGDPRTLLRP#YGLDVW out-of-frame - in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) cagcctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaagggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgacccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8659 JY8QFUQ01AS28D productive Homsap IGHV3-23*03 F (see comment) 522 71.43 155/217 nt Homsap IGHJ2*01 F 166 79.25 42/53 nt Homsap IGHD3-3*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARVRNSNWYFDHW in-frame + Low V-REGION identity (71,43% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgaagacatgtttaagagtttcggattgacgtgggtccgtcaggctccagggaaggggctggagtgggtcgcaggaataaacaattacaatggtgcaactttctatgctggccccgtaaagggccgcttcaccgtctctcgagataaagaaaagaccattttttatctacaaatggacaacgtgagggtcgacgacacgggcgtttatttctgtgcgagagtcaggaatagtaattggtacttcgaccactggggccgcggcgcactagtcacagtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8660 JY8QFUQ01AG60V productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.37.11] CARGLAVILGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 156 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +8661 JY8QFUQ01A4A0M No results +8662 JY8QFUQ01CFE1A No results +8663 JY8QFUQ01DQ9QD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgtgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8664 JY8QFUQ01DNFAX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 797 85.32 186/218 nt 83.94 183/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATRNKMGISTPVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'A' (1 nucleotides at position 170 to 170 in the user submitted sequence), (cause frameshift); cctctggattcaccGttcagtagatactggatgcactgggtccgccaggctcctgggaAaggggctggagtgggtctcaagtattggaactactgagggtagctcatattatgcagactccgtgaagggccggttcaccatctccagagacaactcccagactacgctgAtttttggagatgagcagcctgagagacgaggacacggccgtatattactgtgcgacaaggaataaaatgggaattagtacgcctgttgactactggggccagggaaccctagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8665 JY8QFUQ01A8KHD productive Homsap IGHV3-9*01 F (see comment) 793 84.93 186/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [2.17.38.11] CGRIAKPGLGALDLW in-frame - Low V-REGION identity (84,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ggcgttggattcacttttaatgaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctggggccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8666 JY8QFUQ01A2ECA productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 768 82.96 185/223 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 13 8.10.13 [1.17.38.11] CATDSPTGYYAFDVW in-frame + Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctgggttcgttttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8667 JY8QFUQ01CLSYK No results +8668 JY8QFUQ01AKBIM productive Homsap IGHV3-48*01 F 886 90.28 195/216 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARESTWEFTPDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) tctggattcagtttcagtgactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagttctagtagtaccctatattatgcagactctgtgaagggccgattcaccgtctccagagacaatgacaagagttctctgtatctgcaaatgaccggcctgagagccgaagacacggcgacttattactgtgcgagagagtcgacgtgggaatttactcctgactcctggggcccggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +8669 JY8QFUQ01ABCA0 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 795 84.3 188/223 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD3-16*01 F 2 8 10 13 8.10.13 [1.17.38.11] CSTGGPNGYESTYPW in-frame + Low V-REGION identity (84,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaatatcaagtggatgagttgggtccgccaggctccggggaaggggctggagtgggttggccgcatcaagagcacctctgatggtgggacaacagactccattgcacacgtcaaagacagattcatcatctcaagagatgattcaagaaatacactgtacttacaaatgaacaacctgagagtcgaggatacaggcgtctattattgttccacaggagggccaaatggttatgagtctacctatccctggggcccgggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcaacacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8670 JY8QFUQ01BFYTP unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt 88.37 190/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 1 8 7 20 8.7.20 [1.17.38.11] CAREPPRLL*WWLLFVGAFDIW in-frame - stop codons in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 136 to 136 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaggaattattacCtggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccCttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagaacccccgagactattgtagtggtggttactgtttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggactgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8671 JY8QFUQ01BQR98 No results +8672 JY8QFUQ01DLA93 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.37.11] CVSDLAGQKGF# out-of-frame + in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8673 JY8QFUQ01CCFI9 No results +8674 JY8QFUQ01AF4ER productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8675 JY8QFUQ01CXPDA unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 984 93.72 209/223 nt 93.27 208/223 nt Homsap IGHJ4*02 F 199 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 10 X 8.10.X [1.17.38.11] CTTDPRYFWG*R#FDYW out-of-frame + stop codons in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); ctctggattccctttcagcaacacctacatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaaactgatggtgggacaatagaatacgctgcacccgtgaaaggcagattaaccatatcaagagacgattcaaaaaaTcacgctgtatctgcatatgagcagcctgaagatcgaggacacagccgtgtattactgtaccaccgatccccgttacttttgggggtagcgggtttgactactggggccagggaaccctggtcaccgtctcctnagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8676 JY8QFUQ01AU855 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); gtttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8677 JY8QFUQ01B1OZO unknown (see comment) Homsap IGHV3-7*01 F 1026 96.77 210/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8678 JY8QFUQ01C98V3 No results +8679 JY8QFUQ01B92QK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8680 JY8QFUQ01A6WOJ No results +8681 JY8QFUQ01C878R productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1043 96.43 216/224 nt 95.98 215/224 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTRGGYSYAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cttctggattcacctttggtgattatgctatgagttggttccgccaggctccagGggaaggggctggagtgggtaggtttcattggaggcagagctcatggtggggcaacagaatacgccgcgtctgtgaaaggcagattcatcatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattattgtactagagggggatacagttatgcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8682 JY8QFUQ01DDO4Z No results +8683 JY8QFUQ01BQWUF No results +8684 JY8QFUQ01B5EL3 productive Homsap IGHV3-48*01 F 923 91.74 200/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTRQTGNYYYFGVDVW in-frame - cctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8685 JY8QFUQ01DWKI0 unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 943 93.9 200/213 nt 93.43 199/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 X 8.7.X [1.17.38.11] CARGTGLR#DYW out-of-frame + in FR3-IMGT at codon 76 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); tctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattGcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagagggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8686 JY8QFUQ01C4S9T productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 963 92.04 208/226 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [5.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION gccgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8687 JY8QFUQ01BI4NH productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 746 83.26 179/215 nt 82.79 178/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tttcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgatggtgtcgtggaactc +8688 JY8QFUQ01BIBXR productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggccatcgcctgcctggtccagggcttcttccccca +8689 JY8QFUQ01ARGPK No results +8690 JY8QFUQ01AOP9S No results +8691 JY8QFUQ01BRRVB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8692 JY8QFUQ01AZBTF No results +8693 JY8QFUQ01AR9V6 productive Homsap IGHV3-21*04 F 937 92.24 202/219 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARAVSNQVDVW in-frame - gcctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8694 JY8QFUQ01DCOWC No results +8695 JY8QFUQ01AR6RC productive Homsap IGHV3-11*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 14 8.8.14 [1.17.38.11] CTRDDRSVRGVTSDYW in-frame + ctctggattcaccttcagtgaccacttcatgagttggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggcagtggtagtataatatattacgcagactctgtgaggggccgattcaccatctccagggacaacgccaagaattccctctatctgcaaatggacagcctgagagacgaggacacggccgtgtatttttgtacgagagatgatcgctcggttcggggagtcacctcagactactggggccagggaaccctggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8696 JY8QFUQ01C0BGL No results +8697 JY8QFUQ01C13EL productive Homsap IGHV1-8*01 F 912 92.06 197/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [0.17.38.11] CAREGLLGSLGSW in-frame - aggatacaccttcatcagttatgatatcaattgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaacagcggtaacacagggtttgcacagaggttccagggcagagtaaccatgaccaggaacatctccataaacacggcctacatggagctgaccaacctgacatctgatgacacggccgtatattattgtgcgagagaaggtctattgggcagcctaggatcttggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8698 JY8QFUQ01C3Q8J unproductive Homsap IGHV3-48*02 F 891 90.32 196/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARGRKMATSAS#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcgaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8699 JY8QFUQ01DNWE3 unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 134 63.29 50/79 nt 8 X X 8.X.X [1.17.X.X] null + No rearrangement found ctctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8700 JY8QFUQ01AHITW unproductive (see comment) Homsap IGHV2-5*01 F 1044 92.21 225/244 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD2-15*01 F 3 10 7 X 10.7.X [9.17.38.11] CAHSPP*P#NWFDLW out-of-frame - stop codons gaccctcactctgacctgtaccttctctgggatttcactcaccactggtggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggaatggcttgcactcatttattggaacgatgagacgcgctacagtccatctctgagggacaggctcaccatcagcaagggcacctctaaaaaccaggtggtccttacgatgaccaacatggaccctgtggacacggccacatattactgtgcacacagccccccttagcccagaattggttcgacctctggggccagggctccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8701 JY8QFUQ01DCC58 unproductive Homsap IGHV3-7*03 F 842 87.61 191/218 nt Homsap IGHJ5*01 F (see comment) 111 68.63 35/51 nt Homsap IGHD3-16*01 F 1 8 8 X 8.8.X [1.17.38.11] CTRRGFMDV## out-of-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cctccggattcacttttagtgactattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggcccaagggaccacggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa +8702 JY8QFUQ01A8IJI No results +8703 JY8QFUQ01B00R6 productive Homsap IGHV3-11*01 F 855 88.48 192/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVDIRLGDWFFDLW in-frame + ctctggattcaccttcagtgaccactacatgagctgggtccgccaggctccggggaagggtctggaatggatctcatatatcagtacaagtggtaatatggtttattacgcggactctgtgaagggccgattcaccgtctccagggacaacaccaagagctcactgtatctgcaaatgaacggcctcagagtcgaggacacggccgtctattactgtgtcgacataagactgggagattggttcttcgatctctggggccgtggcaccctggtaactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +8704 JY8QFUQ01DQ6JD unproductive (see comment) Homsap IGHV3-48*04 F 915 90.91 200/220 nt 90.45 199/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [2.17.38.11] CVSSPYFYDSNGYW in-frame - stop codons in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtatctatGcccatgacctgggtccgccaggctccagggaaggggctggagtgatttcagtttatcactgataggggtagtacccaatactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8705 JY8QFUQ01BDLXF No results +8706 JY8QFUQ01BKM4D No results +8707 JY8QFUQ01BJAAN unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 998 96.28 207/215 nt 95.81 206/215 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDNYGDY## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8708 JY8QFUQ01BR23F productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 866 88.24 195/221 nt 87.33 193/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [3.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 42 in the user submitted sequence), (cause frameshift) aggcctcctggattcaccCtttggttattatggcatggactggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +8709 JY8QFUQ01CL9VP productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*07 F 957 94.39 202/214 nt 93.93 201/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 34 of V-REGION: 5 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) tctggattcaccgtcaactagaaactacatgagctggatccggcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8710 JY8QFUQ01C5A8M No results +8711 JY8QFUQ01AWF0A productive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame + ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +8712 JY8QFUQ01AD3IP No results +8713 JY8QFUQ01C9DGQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +8714 JY8QFUQ01DILKD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F (see comment) 87 64.58 31/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGVIAVAG#DFDCW out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagggggttatagcagtggctggtacgactttgactgctggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggctgacggtgtcgtggaactca +8715 JY8QFUQ01AQJ8I productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCGNGACHVADYW in-frame + ctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8716 JY8QFUQ01CH3BJ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 850 88.43 191/216 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame - tctggattcagtcctaccgatttttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctccttcaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8717 JY8QFUQ01DGNVX unproductive (see comment) Homsap IGHV3-9*01 F 445 90.74 98/108 nt 89.81 97/108 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 X 16 8.X.16 [1.15.11.11] CAKDGSAIPVTGTYFEYW in-frame + stop codons in FR2-IMGT, from codon 54 of V-REGION: 109 nucleotides (from position 75 in the user submitted sequence), (cause frameshift) ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggaatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8718 JY8QFUQ01AT9J8 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 119 54.62 71/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +8719 JY8QFUQ01CKPOL No results +8720 JY8QFUQ01BSXDU No results +8721 JY8QFUQ01AGMDN No results +8722 JY8QFUQ01CRXFK productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8723 JY8QFUQ01AL8UN productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame - tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8724 JY8QFUQ01DHN9E productive Homsap IGHV4-34*08 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [1.17.38.11] CTRGRSDAWELSDHW in-frame + ctctggattcacctttggtagctattggatggcctggatccgccagtccccagggaaggggctggagtggattggggaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagtcgagtcaccatatcattagacacgtccaacaaccaagtctccctgaggttgagctctgtgaccgccgcggacacggctgtgtattactgtacgcgagggcgatccgacgcgtgggaattatcggaccactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8725 JY8QFUQ01CJJ54 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 88.02 191/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaCcctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +8726 JY8QFUQ01B1XHB productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-3*02 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [2.16.38.11] CAKNGPGGGWYAEQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcgtctggattcagtttcagtgactatgccatgcactgggtccgccagactccaggcaagggctggagtgggtggcagttatttcatatgatgggagagagaagtactatgcagactccctgaagggccgattcaccacctccagagacaactccaagaaaatgctgtatctccaagtgaatagcctgagacctggagacacggctgtgtattactgtgcgaaaaatgggccggggggtggctggtacgctgagcagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8727 JY8QFUQ01CTT6Y productive Homsap IGHV3-11*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame + ctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +8728 JY8QFUQ01A8IV0 No results +8729 JY8QFUQ01CFHCJ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 823 87.04 188/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - gtctctggggactccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccatggcttcttccccca +8730 JY8QFUQ01CLD9L productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8731 JY8QFUQ01COTXW productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaact +8732 JY8QFUQ01BP3Y5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8733 JY8QFUQ01DP4NP unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CARSKYSLGRLPDF## out-of-frame + ctctggattcattttcaacactcatgccatgacttggctccgccaggctccagggaaggggctggagtgggtctcagccattagtggcgatgctactggcactttttacgcagactccgtgaagggccggttcaccatctccagagacaatgtcaagaacacggtggatttgcagatgaacaacgtgagagtcgaggacacggccttatattactgtgcgaggagcaaatatagtcttggccgcttacctgacttctggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8734 JY8QFUQ01AV7G8 No results +8735 JY8QFUQ01BICQI unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [1.17.38.11] CANACPPYNWN#YFYYYGMDVW out-of-frame - tctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctgccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8736 JY8QFUQ01CO9YE productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 897 90.0 198/220 nt 89.09 196/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaAggggctggagtggaTttgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8737 JY8QFUQ01C8DQF productive Homsap IGHV4-61*02 F 960 93.18 205/220 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame - ctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8738 JY8QFUQ01DFQZY productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8739 JY8QFUQ01DMA0D unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +8740 JY8QFUQ01DS7GW unknown (see comment) Homsap IGHV1-NL1*01 P 90 56.79 46/81 nt 2 X X 2.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagagac +8741 JY8QFUQ01DE480 productive Homsap IGHV3-9*02 F 891 90.32 196/217 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + ctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccga +8742 JY8QFUQ01AK37Y productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame + gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +8743 JY8QFUQ01ARYWV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKCKAPGKVDWFDPW in-frame + tctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctggtaaggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttctt +8744 JY8QFUQ01DRUC1 productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [2.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); gtctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8745 JY8QFUQ01DOFPT No results +8746 JY8QFUQ01BJ5BD No results +8747 JY8QFUQ01BX25Z No results +8748 JY8QFUQ01BIWZU No results +8749 JY8QFUQ01AKUKJ productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 957 92.38 206/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.38.11] CTHLREEMSYEW in-frame + ctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8750 JY8QFUQ01DG5KX productive Homsap IGHV3-66*02 F, or Homsap IGHV3-66*03 F 867 89.72 192/214 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-25*01 F 1 8 7 11 8.7.11 [1.17.38.11] CARDGRGGDLDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gtctgggttctccgtcagtttcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatctatgccgatggaagtacattctatgcagactccgtgaagggccgattcatcatctccagagacaattcaaagaacacgctcaatcttcaaatgaatagtttgagagttgacgacacggctgtgtattactgtgcgagagatgggcgcggcggtgaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgcagcagcccctaaggtcttccgctgagcctcgacacgcacccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8751 JY8QFUQ01C8CMM unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 125 100.0 25/25 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found tccggggacagtgtctctagcaaca +8752 JY8QFUQ01B3AYN productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 928 91.78 201/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [2.17.38.11] CTKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); gcctctggattcaccGttcagtagatactggatgcactGgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8753 JY8QFUQ01AN3PN No results +8754 JY8QFUQ01CMNEA No results +8755 JY8QFUQ01A7PTY unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD2-21*01 F 1 8 8 X 8.8.X [1.17.38.11] CARRSGRDGG#WFDSW out-of-frame + Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tctctggattcatctttgccgactatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtcgcagatattaatggaagaggtgctgccgcacactacgcagactccgtgacgggccgcttcaccctctacaaagacggttccaagaatacgatgtatctgcaaatgaggaccctgagagacgacgacacggccaaatattactgtgcgagacgaagtgggcgtgatggggggcctggttcgactcctggggccagggaacccgtggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8756 JY8QFUQ01B37ED unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGVIAVAG#DFDCW out-of-frame + cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagggggttatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactca +8757 JY8QFUQ01CXOED unproductive Homsap IGHV3-48*01 F 1066 99.54 215/216 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGSGWYRDFDY# out-of-frame + tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgcgagaggcagtggctggtacagggactttgactactgggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +8758 JY8QFUQ01DLZRP unknown (see comment) Homsap IGHV4-4*07 F 818 86.98 187/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccgaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactca +8759 JY8QFUQ01DRK6U unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggctatagcagcgaacgaaactactggggccagggaagccctggctcaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +8760 JY8QFUQ01BKDJ4 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDLTGYSSERNYW in-frame + ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +8761 JY8QFUQ01BWN2J productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame - ctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8762 JY8QFUQ01AE4C2 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 728 82.33 177/215 nt 81.86 176/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 2 7 8 11 7.8.11 [1.17.38.11] CARASTLRYLDRW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) tctggatttacattagtgattataatatgaattgggtccgccgggctccagggaaggggctggaatatgtcgcaaccattacaactgggagtggtcaaatctactacagtgactcagtgaggggccgcttcaccatctctagagacgacgccaagaattcactttatctgcagatgaacaacctgagaggcgaggacacggctgtctatttttgtgcgagagcctccacactacgatatcttgaccgctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8763 JY8QFUQ01BA0MC productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8764 JY8QFUQ01ASM5Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 926 92.09 198/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [0.17.38.11] CAKGYHGPFDSW in-frame + ctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacacatactactcagactccgtgaggggccggttcaccatctccagagacaacgccaagaacacgatgtatctgcaaatgaacaccctgagagacgaggacacggccgtctatttctgcgcgaaaggttaccacggcccctttgactcttggggccggggaaccctggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8765 JY8QFUQ01BYKTM unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFD#PW out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8766 JY8QFUQ01DSMIM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8767 JY8QFUQ01ANF7B unknown (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacatttagtaactactggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctcttccaccaagggcccatccgtcttccccctggcgcccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactca +8768 JY8QFUQ01ATBJS No results +8769 JY8QFUQ01DDV0C productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 894 91.12 195/214 nt 90.65 194/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-18*01 F 1 8 8 15 8.8.15 [0.17.38.11] CAIVDTNLVSATGKDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcagcaactactatagacactgggtgcgacaggCcccctggacaagggcttgagtggatgggaatgatcaaccctagtagtgattacaaatattacgcacagaaatttcagggcagagtcaccatgaccagggacacgtccacgagcacagtcttcatggagctgagtagcctgagatctgacgacacggccgtgtattattgtgcaatagtggacacaaatttggtttcggcgaccggtaaagactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8770 JY8QFUQ01BIVWL productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 858 89.25 191/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [1.17.38.11] CTRELRVAAARDGVDIW in-frame + ctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggagtgggtctcagtaatttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8771 JY8QFUQ01CFEQP unknown (see comment) Homsap IGHV1-2*01 F, or Homsap IGHV1-2*02 F or Homsap IGHV1-2*04 F or Homsap IGHV1-2*05 F or Homsap IGHV1-46*01 F or Homsap IGHV1-46*03 F (see comment) 259 69.91 79/113 nt 8 8 X 8.8.X [0.17.4.X] null - No rearrangement found Low V-REGION identity (69,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcaccgaccactatctgcactgggtccgacaggcccctggacaagggcttgagtggatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8772 JY8QFUQ01AKRAQ productive (see comment) Homsap IGHV1-8*01 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-10*01 F 3 8 8 17 8.8.17 [0.17.38.11] CARGPDEGPLYYYYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 95 of V-REGION: 'AGG' (3 nucleotides at position 185 to 187 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccaattatgatatcaactgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaaaattggaaacacaggctctgcacagaagttccagggcagagtcaccatgaccaggaacacctccacaagcactgcctacatggagctgagcggcctcAGGaagtctgacgacacggccgtatattactgtgcgagagggccggatgagggtcccctttactactattatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +8773 JY8QFUQ01CH4RG No results +8774 JY8QFUQ01A098V No results +8775 JY8QFUQ01DL72Y No results +8776 JY8QFUQ01AKV85 unproductive Homsap IGHV3-48*01 F 1085 99.54 217/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CASNFWSGSPG##YYYGMDVW out-of-frame - cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgaatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8777 JY8QFUQ01BEJX1 unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 135 77.78 35/45 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found ctctggattcagcctcgccacttatagtatgagttgggtccgcca +8778 JY8QFUQ01BTDTI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccatggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8779 JY8QFUQ01CPDBH No results +8780 JY8QFUQ01BXNFF productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-25*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARHEGYNSRYYYFGYW in-frame + tctggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +8781 JY8QFUQ01CIGNE productive Homsap IGHV3-11*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARVKYSSSWSSILDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaacttcggtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtttcattcattagtagtcctggtatcaggagtttctacgcagactctgtgaagggccgattcactatttccagggacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgaggacacggccatatattactgtgcgagagtgaaatatagcagcagctggtcctcaatccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8782 JY8QFUQ01DWRPB No results +8783 JY8QFUQ01CC4CT productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 883 89.5 196/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 8 16 8.8.16 [2.17.38.11] CAKDRYPRSTAITAPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 27 of V-REGION: 'CA' (2 nucleotides at position 9 to 10 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); gcctctggCAttccccgtttagcaactGatgccatgacctgggtccgccaggctccaggggagggactggaatgggtctcaagtattagaggtagtggtgacaggacatcctacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagctgaacaacctgagagccgaggacagggccgaatattactgtgcgaaagatcgctaccctcggtcgacagctattacagcgcctgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8784 JY8QFUQ01AIK4Q productive (see comment) Homsap IGHV3-48*01 F (see comment) 759 84.11 180/214 nt 83.18 178/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaAaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8785 JY8QFUQ01B56HH productive Homsap IGHV2-5*02 F 1134 96.31 235/244 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 10 7 13 10.7.13 [9.17.38.11] CAHRGNYGDYVFDSW in-frame + gaccctcacgctgacctgcaccttctctggattctcacttagcactagtgggatgggtgtgggctggatccgtcagcccccaggaaaggccctggaatggcttacactcatttattgggatgatgataagcgctacagcccatctctgaagagcaggctcgccatcaccaaggacacctccaaaaatcaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattattgtgcacacagagggaattacggtgactatgtttttgactcctggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +8786 JY8QFUQ01BU46G productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaataCgggggggcactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +8787 JY8QFUQ01B2W2D No results +8788 JY8QFUQ01BUXGM productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 974 93.67 207/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 2 8 10 14 8.10.14 [0.17.38.11] CTTRPRGWEPLGLDYW in-frame - ctggattcactttcagtaacgcctggatgatctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagaccaaagctgatggtgcgacaacagactactctgcacccgtgagaggcagattcatcatctcaagagatgattcaaaaaacatggcgtttctgcaaatgaacagcctgaaaaccgaggacacagccctttattactgtaccacacggccccgggggtgggaaccacttgggctcgactactggggcctgggaaccctggtcaccgtctcctctgcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8789 JY8QFUQ01B2GCQ No results +8790 JY8QFUQ01AGKW1 No results +8791 JY8QFUQ01BUO7F No results +8792 JY8QFUQ01A4DRB unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttagcaattttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttgtgagtggtagtggcgatagaacagactacgcagactccgtgaagggccggttcactatctccagagacaattccaagagtacactattcctgcaaatgcacagcctgagagtcgaggacacggccgtatattactgtgcgaaagctggatatagtagtgcgcgaacccacatggacgtctggggccaaggggtcgcgggtcaccgtcctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +8793 JY8QFUQ01CAFZQ No results +8794 JY8QFUQ01CWH2P No results +8795 JY8QFUQ01BGO9W No results +8796 JY8QFUQ01C03N1 No results +8797 JY8QFUQ01A3V1E productive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); ctctacattcacgGtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8798 JY8QFUQ01A365U productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + ctctggattccccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaggggccgattcaccatctccagagacaacgccaggaactcattgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8799 JY8QFUQ01CIFO7 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctactggatgcactGgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8800 JY8QFUQ01B5U19 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [2.17.38.11] CVRRGMVAGRYDAFDIW in-frame - gcctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8801 JY8QFUQ01B5I6A unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGL*QWL##DFDCW out-of-frame + stop codons ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggttatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8802 JY8QFUQ01DIO55 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca +8803 JY8QFUQ01AMI0B productive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame + ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +8804 JY8QFUQ01CK79T unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKEEGATGVYYVDH# out-of-frame - gcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactgggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8805 JY8QFUQ01ADRIZ No results +8806 JY8QFUQ01CPP87 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 107 57.95 51/88 nt 8 2 X 8.2.X [2.17.X.X] null - No rearrangement found stop codons cctcctggattcacctttagcagctatgccatgagctgggctcaagggactacttccccgaaccggtgacggtgtcgtggaactccag +8807 JY8QFUQ01BX6JB productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame + tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca +8808 JY8QFUQ01DRVPT No results +8809 JY8QFUQ01CEGRO No results +8810 JY8QFUQ01BARWR No results +8811 JY8QFUQ01CDELV productive (see comment) Homsap IGHV3-48*03 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD2-15*01 F 2 7 8 13 7.8.13 [2.17.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagttcttatgcatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8812 JY8QFUQ01C64L9 No results +8813 JY8QFUQ01A82RW productive Homsap IGHV3-30*10 F 927 92.17 200/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD3-9*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARDRDFDFPAYGLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacttcagtaactatgctgtgcactgggtccgccgggctccaggcaaggggctagagtggatgggagttatatcatttgatggagataataaatactacacagactccgtgaagggccgattcaccatgtctagagacaattccaagaacacactatatctccaaatgaacagcctgtcagctgaggacacggctgtctattactgtgcgagagatcgagatttcgactttcctgcttacggtttggacgtctggggccaagggaccacggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8814 JY8QFUQ01CPWUK productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1041 97.27 214/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame + ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8815 JY8QFUQ01BJYDO productive Homsap IGHV1-3*01 F 912 92.06 197/214 nt Homsap IGHJ4*02 F (see comment) 231 97.92 47/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDGEPLGGDYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggatacaccttcacttcttatgctgtaaactgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctggcacgggtaacacaaaatattcacagaagtttcagggcagagtcaccattaccagggacacatccgcggacacagtcttcatggagctgagcagtctaagatctgaagacacggctgtgtattattgtgcgagagatggggagccactgggaggcgactactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8816 JY8QFUQ01C6MWX No results +8817 JY8QFUQ01BNVJT No results +8818 JY8QFUQ01AEUM3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame + ctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8819 JY8QFUQ01BVL9C productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGYW in-frame - ctctggattcagctttagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaaatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtttttgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgattagtagtgatttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8820 JY8QFUQ01AT3EI No results +8821 JY8QFUQ01CM72D productive Homsap IGHV3-48*04 F 900 90.78 197/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcgccttcagtagttccagcatgaactgggtccgccagggtccagggaaggggctggagtggatttcacacattaggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8822 JY8QFUQ01C3CHZ productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctgcgccctgctccaggagcacctccgagagcacagccgccctggctgcctggcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8823 JY8QFUQ01AQ049 unproductive Homsap IGHV3-30*08 F, or Homsap IGHV3-30*16 F 918 91.71 199/217 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGKAGHTHYGLDV## out-of-frame + ctctgcattcaccttcagtagttatgctatgcactgggtccgccaggccccaggcaaggggctagagtgggtggcagttatatcaaatgatggaaattataacgactatgcagactccgtgaaggggcgattcaccatttccagagacaactccaagaacacgctatttctacaaatgaatagcctgagagttgaggacacggctgtctataactgtgcgagaggaaaggctggccatacccactacggattggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8824 JY8QFUQ01BXLFA productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD5-18*01 F 1 8 8 19 8.8.19 [1.17.38.11] CARSGDPGMVHGVYYYNIDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); tctggaattcaccttcagaagctatagcatgaactGgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagtaacatatactatgcagactcagtggagggccgattcaccatctccagagacaacgccaagaattcactgtttctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatctggggatccaggtatggttcatggcgtgtactactacaatatagacgtctggggccaagggaccacggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8825 JY8QFUQ01BS2DY unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 616 75.93 164/216 nt 75.46 163/216 nt 7 8 X 7.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8826 JY8QFUQ01BS3ZN unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F (see comment) 650 76.92 170/221 nt 76.47 169/221 nt 10 7 X 10.7.X [2.16.38.X] null - No rearrangement found Low V-REGION identity (76,92% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gtctctggtggctccatcagcagtagtagttactactgggcctggatccgccagccccagggaaggggctggagtgccttgggagcatcttttatagtgggcgcaccaaccaggacccgtccctcaagagtcgagtcaccttatccgttgacacttccaagaaccagttctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +8827 JY8QFUQ01DG7LK No results +8828 JY8QFUQ01DL61R productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtAgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8829 JY8QFUQ01ARGUK No results +8830 JY8QFUQ01CYMNK No results +8831 JY8QFUQ01AG3HE productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame + ctctggattcaccttcagtaactacagaatgaattgggtccgtcaggctccagggaaggggctcgaatgggtctcgtccattaccagttccagtagttacatatactacgcagactcggtgacgggccgattcaccatctccagagacaacgcccagaactcgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +8832 JY8QFUQ01ACPNW unproductive Homsap IGHV3-66*02 F 894 91.12 195/214 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [1.17.38.11] CAKLADTGEWSNRIFYF# out-of-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatattacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8833 JY8QFUQ01DBJFZ unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 90 81.48 22/27 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found ctccgggggacagtgtctctaccaaca +8834 JY8QFUQ01BZFIM productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8835 JY8QFUQ01AJ0AZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.16.38.11] CAKEEVWYGSGRGGPKDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'GGA' (3 nucleotides at position 90 to 92 in the user submitted sequence), (do not cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 32 in the user submitted sequence), (cause frameshift) gcctctggattcacctttaggagctatgccagagctgggtccgccaggctccagggaagggggctgagtgggtctcaactattagtggtGGAaatgttgatagcacagactacgcagattccgtgaagggccggttcaccatctccagagacaattccaagaacacattgtatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaaagaagaagtgtggtatggttcggggagaggggggccaaaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8836 JY8QFUQ01BEABE productive (see comment) Homsap IGHV3-7*01 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARVNKDSTDMW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtgactattggatgaggtggttccgccagcctccaggaagggggctggagtAgggtggccagcataaaagaagatggaagtgagaaaggttatgtggactctgtgaagggccgcttcaccatcgccagagacaacgcccagaaatcactgtttttgcagatgaacagcctgagaggcgaggacacggctgtgtatttctgtgcgagagtcaacaaggactctactgatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +8837 JY8QFUQ01CUDXR No results +8838 JY8QFUQ01B4Z8J No results +8839 JY8QFUQ01DL6YG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDRRGPNDY## out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcggcggggacctaatgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8840 JY8QFUQ01A36OR productive Homsap IGHV3-21*04 F 990 95.39 207/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame + ctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8841 JY8QFUQ01ALH3K unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ1*01 F 89 63.46 33/52 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8842 JY8QFUQ01BDE6W No results +8843 JY8QFUQ01BZJD6 productive (see comment) Homsap IGHV2-5*02 F, or Homsap IGHV2-5*08 F 856 90.0 189/210 nt 88.57 186/210 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-13*01 F 1 8 7 13 8.7.13 [1.15.38.11] CARKYGSSTNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 31 of V-REGION: 'T' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 7 nucleotides (from position 30 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 4 nucleotides (from position 73 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagTcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcatttattgggatgatgataagcgctacaacccatctctgaagagcaggctcaccatcaccaaggacacctccaaaaaccaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattattgtgcacgcaagtacggcagcagcacgaattggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +8844 JY8QFUQ01DHRRE No results +8845 JY8QFUQ01BDGRO productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame - Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtg +8846 JY8QFUQ01DDD10 No results +8847 JY8QFUQ01AEPJ7 productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F or Homsap IGHV4-31*06 F or Homsap IGHV4-31*08 F 834 86.82 191/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGRPSDRGEYYFDYW in-frame + ctctggcgcctccatcagcagtggtctttactactggagctggatccgccaattcccagggaggggcctggaatggattggattcactctttacagtgggagcacccactacaacccgtccctcaagagtcgacttaggatttctatagacacgtcaaagaaccagttctccttgaatctgacttctgtgactgccgcggacacggccgcatattactgtgcgagaggtcgcccttcggatcggggagaatactactttgactactggggtcaggcaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +8848 JY8QFUQ01CEMBF unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 391 88.78 87/98 nt 86.73 85/98 nt 7 7 X 7.7.X [1.16.X.X] null + No rearrangement found in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggattcaccttggcagctatatcatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtaggggtgttgaca +8849 JY8QFUQ01ADQXM No results +8850 JY8QFUQ01DARQJ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 13 8.8.13 [1.17.38.11] CARGGGGKSIPLDNW in-frame + gtctggcttcacgttcagtagttatggcatgcaatgggtccgccaggctccaggcaaggggctggagtgggtggcagttatttggtatgatggaagtaataaatattatgcagactccgtgaagggccgattcgacatctccagagacaattccaagaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatgtaccattgtgcgagaggcggcggtggtaagtccattccacttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +8851 JY8QFUQ01BXI8V unproductive (see comment) Homsap IGHV3-11*01 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [2.17.38.11] CAKDPGGKSGSYGLDHW in-frame - stop codons in FR3-IMGT at codon 80 of V-REGION: 'A' (1 nucleotides at position 145 to 145 in the user submitted sequence), (cause frameshift); gcctctgggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccAagggtcaacgccaagaactcactgtctctgtaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgaaagatccggggggaaaaagtgggagctacggacttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8852 JY8QFUQ01A2HU3 productive (see comment) Homsap IGHV4-4*07 F 828 87.1 189/217 nt 86.18 187/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [2.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 212 to 212 in the user submitted sequence), (cause frameshift); tgtctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgCaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtaCtttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8853 JY8QFUQ01B81HO productive (see comment) Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt 80.65 175/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'C' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctctggattCccccttcaatatatggagcatgaattgggtccgccaggctcCcggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8854 JY8QFUQ01CL33K unknown (see comment) Homsap IGHV1-2*02 F 503 86.47 115/133 nt 8 8 X 8.8.X [0.17.11.X] null + No rearrangement found tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaacc +8855 JY8QFUQ01BULPN No results +8856 JY8QFUQ01DKQ6P productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8857 JY8QFUQ01APZAR unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 558 72.81 158/217 nt Homsap IGHJ1*01 F (see comment) 19 63.64 7/11 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (72,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity). The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctagattcatctttagtagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactatcagtggtagtggtgataacacatactacgcagactccgtgaagggccggttcaccatctccagagacaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +8858 JY8QFUQ01B74B9 unproductive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKIGRAAAGPILR#W out-of-frame + ctctggattcacctttgatgagcatgccatgcactgggtccggcaagttccggggaagggcctggagtgggtctctggtgttacttggaatagtggtgtcatagactatgcggactctgtgaagggccgattcaccatctccagagacaacgccaggaattccctgtatctacaaatgaacagtctgagaactgatgacacggccttctatttctgtgcaaagattggccgagcagcggctggtcccattttgaggcttggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8859 JY8QFUQ01COHK1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 883 89.5 196/219 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKYPSISGWYTP#NWFDPW out-of-frame - ggctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatacccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8860 JY8QFUQ01C8695 unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 837 87.56 190/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggatacacctttggcattcactggattgcctgggtgcgccagaagcccgggaaaggcctagagtggatggggatcatctatccaggcgactctgacaccacatacagtccgtccttccaaggccaagtcaccatctcagtcgacaagtccagcaataccgcctatttacagtggatcagcctgagggcctcggacaccgccatgtattattgtgtgagacggggccagacaagataccgactcgtctgaagctttgacatttggggccaagggacaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8861 JY8QFUQ01DH7XB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-16*02 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGQFGTVMDYW in-frame - ctctggattcacctttaacgactatggcatgacttgggtccgccaggctccagggatggggctgcagtgggtcgcaaccattagtggaagtggcgacagaacattctacgcagactccgtgaagggccgcttcatcgtttccagagacaactccaagaacacgctgtatctgcaaattaccagcccgagagccgaggacacggccgttttttattgtgcgaaaggccagtttggtaccgtcatggactattggggccagggaacccaggtcgtcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8862 JY8QFUQ01DHA6Y unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 102 53.03 70/132 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8863 JY8QFUQ01A3W23 unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F (see comment) 237 60.12 101/168 nt 8 8 X 8.8.X [0.17.22.X] null + No rearrangement found Low V-REGION identity (60,12% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcagcaactactatagacactgggtgcgacaggcccctggacaagggcttgagtggatgggaatgatcagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8864 JY8QFUQ01AT86Y No results +8865 JY8QFUQ01A5D0V No results +8866 JY8QFUQ01APZ3Q productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDYGDCRGGICYAEPLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'CA' (2 nucleotides at position 12 to 13 in the user submitted sequence), (cause frameshift); cctctggattcCAgcctcgccgacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtatatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8867 JY8QFUQ01BLQB5 No results +8868 JY8QFUQ01DLU9F productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8869 JY8QFUQ01BE4VS productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame - ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8870 JY8QFUQ01DS5CD No results +8871 JY8QFUQ01DUXI2 unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 2 8 7 X 8.7.X [1.17.38.11] CARPHI*QRPGR#FDTW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggccccacatatagcagcggccgggacgctttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8872 JY8QFUQ01ACLY7 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatCccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8873 JY8QFUQ01BPL16 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +8874 JY8QFUQ01AW5C9 No results +8875 JY8QFUQ01CZXNB productive Homsap IGHV3-9*01 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [0.17.38.11] CAKGGGNGDLDYW in-frame - tggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattacttggaacagtggtaggataggctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +8876 JY8QFUQ01CPGIT productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 930 90.58 202/223 nt 89.24 199/223 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-22*01 F 2 8 10 14 8.10.14 [1.17.38.11] CTSRYYDPSGYWSDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 82 of V-REGION: 'C' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 94 of V-REGION: 'G' (1 nucleotides at position 196 to 196 in the user submitted sequence), (cause frameshift); ctctggggtcaccttcagtgacgcctggatgacctgggtccgccaggctccagggaaAGggggctggagtgggttggccgtattagaagcagagttgatggtgggacagtggactacgctgcacccgtgaaaggcagattcaccatctcaagagatgaCtccgaaaaacacactatatctacaaatgaacagcctGgaaaatcgaggacacagccatgtatttctgcaccagtcgatactatgatcctagcggttactggtccgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8877 JY8QFUQ01ADX4W productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1040 97.71 213/218 nt 97.25 212/218 nt Homsap IGHJ3*02 F 88 64.0 32/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggGggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +8878 JY8QFUQ01BCO3O productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 862 89.67 191/213 nt 89.2 190/213 nt Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.37.11] CARDPRDYCSGGYCFVGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 92 of V-REGION: 1 nucleotides (from position 176 in the user submitted sequence), (cause frameshift) ctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +8879 JY8QFUQ01BLGQV unproductive (see comment) Homsap IGHV3-33*05 F (see comment) 752 83.03 181/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CVKGTWIQ*LRP#DYW out-of-frame + stop codons Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaagggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctgcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8880 JY8QFUQ01CT2Y2 productive (see comment) Homsap IGHV3-7*01 F 923 91.74 200/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-21*02 F 3 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); cctctggattcccttttagaacctattggatgagttGgggtccgccaggctccagggGAaaggggctggagtGgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctcagg +8881 JY8QFUQ01CYU3K productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8882 JY8QFUQ01DTLJ4 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 472 71.07 140/197 nt 8 7 X 8.7.X [1.17.32.X] null - No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DTLJ4 ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (71,07% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8883 JY8QFUQ01DL9FI unproductive (see comment) Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGAG*PFL##YYSGLDVW out-of-frame + stop codons ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggcagggtgaccctttttgccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8884 JY8QFUQ01A4FR2 unproductive Homsap IGHV3-66*02 F 876 90.19 193/214 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [1.17.38.11] CAALHDPPWGWLD#PG out-of-frame + ctctggattcagcgtcaacaacaactacatgaactgggtccgcctggctccagggaagggtctggagtgggtctcagttatttatagaggtggtaatacattctacacagactccgtgaagggccggttcaccatctccagagacatttccaagaacactttgtatcttcaaatgaacagtctgacaactgaggacacggctgtgtactattgtgcggccctccacgaccctccttggggttggctcgacccctggggccggggaaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8885 JY8QFUQ01AC0N1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8886 JY8QFUQ01C5WBE No results +8887 JY8QFUQ01BNHDT No results +8888 JY8QFUQ01CY19E No results +8889 JY8QFUQ01C67S6 No results +8890 JY8QFUQ01APJQA unproductive Homsap IGHV3-48*01 F 810 86.18 187/217 nt Homsap IGHJ4*03 F (see comment) 114 70.83 34/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRGAGLDV## out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaggggctggagtgtgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctggacgtctgggggccaagggaccacggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +8891 JY8QFUQ01B383T productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +8892 JY8QFUQ01DLITF No results +8893 JY8QFUQ01A8T70 No results +8894 JY8QFUQ01AI35Q unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDNYGDYW# out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8895 JY8QFUQ01A4P7X productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1090 100.0 219/219 nt 99.09 217/219 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [2.16.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) agcctctggattcaccGtttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8896 JY8QFUQ01B98PC No results +8897 JY8QFUQ01DGLEH productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8898 JY8QFUQ01CCDJP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagAccctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8899 JY8QFUQ01ASBMB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 880 90.61 193/213 nt 90.14 192/213 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.37.11] CVSDLAGQKGFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 165 in the user submitted sequence), (cause frameshift) aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8900 JY8QFUQ01DASVR productive Homsap IGHV1-2*02 F 970 94.86 203/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 2 8 8 11 8.8.11 [0.17.38.11] CARSTWRGAPDYW in-frame - tggatacaccttcaccggctactatatgcactgggtgcganaggcccctggacaaggccttgaatggatgggatggaccaaccctaacggtggtggcgcaaactatgcacagaagtttaagggcagggtcaccttgaccagggacacgtccatcagcacagcctacatggagctgagcaggctgaggtttgacgacacggccgtgtatttctgtgcgagatcgacctggagaggggcacctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8901 JY8QFUQ01DRJW6 No results +8902 JY8QFUQ01AD5QJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD3-3*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKQTIFDYYYYGLDVW in-frame - ctctggattcatgtttagtagctttcccatggcctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8903 JY8QFUQ01ATT5V productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +8904 JY8QFUQ01A13CK productive Homsap IGHV3-7*01 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATDDSNGWDEVADYW in-frame + cctctggattcaccttcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8905 JY8QFUQ01BIL8C unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaagaggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +8906 JY8QFUQ01BWZ5H productive Homsap IGHV3-9*01 F 810 86.18 187/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD5-24*01 ORF 3 8 8 17 8.8.17 [1.17.38.11] CVKDRKAGGYNLLDAFDIW in-frame + ctctggattcaccttcgacgactatgtcatgcattgggtccggcaagttccagagaggggcctggagtgggtcgcaggcattaatggggaaagtaatagttttggctctgtggactctgtaaagggccgattcaccatctccagagacaaggccaagaataccctgtatttgcaaatgaatagcctgagagttgaggacacggccttgtattattgtgtgaaagatagaaaagctggtggctacaatctgttggatgcttttgatatctggggccaagggacaatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8907 JY8QFUQ01B6ODL No results +8908 JY8QFUQ01CAR1O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CAKDRDPGYCLSNSCVDGLAFDSW in-frame + cctctggattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctccggtattagtggtagtggtggtaacacatacttcgcagactccgtgaagggccggttcaccatctccagagacaattccaggaacacgctgtttctacagctgaacagcctgagagccgccgacacggccgtatattactgtgcgaaggatcgtgacccgggatattgtcttagtaatagctgtgttgacggcctagcctttgactcctggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +8909 JY8QFUQ01C44TZ productive (see comment) Homsap IGHV3-23*05 F 826 87.79 187/213 nt 86.85 185/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 7 7 10 7.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggatcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +8910 JY8QFUQ01DME8N productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGHSYYVSSGPDYW in-frame + ctcgggattcaacttcaagtccaacaccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8911 JY8QFUQ01APK0W productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8912 JY8QFUQ01CUUTL unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.17 200/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGYHGPFDS## out-of-frame + ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacacatactactcagactccgtgaggggccggttcaccatctccagagacaacgccaagaacacgatgtatctgcaaatgaacaccctgagagacgaggacacggccgtctatttctgcgcgaaaggttaccacggcccctttgactcttggggccggggcaaccctggttaccgtctcctcagcatccccgaccagctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8913 JY8QFUQ01BUNVH productive (see comment) Homsap IGHV3-33*03 F 948 93.93 201/214 nt 92.99 199/214 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 8 7 16 8.7.16 [1.16.38.11] CAREVKYGDDTGGWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaaggggctggagtggtggcaatgattggtatgatggaagccttacatattatgaagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgctgtttctgcaaatgaatagcctgagagtcgaggacacggctctgtattactgtgcgagagaggtgaaatacggtgacgacacgggggggtggttcgacccctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagccctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggccttcttcccccagg +8914 JY8QFUQ01ARRB2 unknown (see comment) Homsap IGHV3-48*01 F 936 92.63 201/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcagcttcagttcctatagcatgagctgggtccgccaggctccggggaaggggctggagtgggtctcatatattagtagtagtggtaggaccatctactacgctgactccgtgaagggccgattcaccatgtccagagacaatgccaagaattcactgtatctacaaatgagcagcctgagagccgaggacacggctgtgtattactgtcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctgtcaggcttcttcccccaa +8915 JY8QFUQ01AUQPF productive Homsap IGHV3-48*02 F 968 94.04 205/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARPAGEGDPFFHYYSGLDVW in-frame + cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8916 JY8QFUQ01AL0GI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 928 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 79 to 81 in the user submitted sequence), (do not cause frameshift); gcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8917 JY8QFUQ01CIW9M unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 650 78.77 167/212 nt 77.83 165/212 nt 8 8 X 8.8.X [0.16.38.X] null - No rearrangement found Low V-REGION identity (78,77% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 2 nucleotides (from position 74 in the user submitted sequence), (cause frameshift) tggattcagctttagcgattttgccatgagttgggtccgccaacctccaggAaaaggggctggagtgggtcgcaaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8918 JY8QFUQ01AT53V No results +8919 JY8QFUQ01ADAE7 productive (see comment) Homsap IGHV2-5*02 F 1080 93.85 229/244 nt 93.44 228/244 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 10 7 12 10.7.12 [9.17.38.11] CAHSVNSWTNFDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'GTTCTCA' (7 nucleotides at position 32 to 38 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttcactgggGTTCTCActcacactcaccactagtggagtgggtgtgggctgggtccgtcagcccccaggcaaggccctggagtggctcgcaatcatttattgggatgatgataagttctacagtccatctctgaagagcagactcaccatcaccaaggacacctccaaaaaccaagttgtccttacaatgaccaacatggaccctgtggacacagccacatattattgtgcacacagtgtcaacagttggaccaattttgaccactggggcccgggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +8920 JY8QFUQ01BPEPF No results +8921 JY8QFUQ01C17CH unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 484 82.86 116/140 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (82,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag +8922 JY8QFUQ01A5H2V No results +8923 JY8QFUQ01A96T1 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [2.17.38.11] CARDPSGSGWAFESW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'AT' (2 nucleotides at position 10 to 11 in the user submitted sequence), (cause frameshift); gcgtctggaATttccctttcagtagagatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatggtatggtatgatggaagtaatacacaccatgcagattccgtgaagggccgattcatcatttccagagacaattccaagaataaagtgtatctgcaaatgaacagtctgagagacgaggacacggctgtctattattgtgcgagagatccgagcggcagtggctgggcctttgagtcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8924 JY8QFUQ01AJDLF unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 883 89.5 196/219 nt 87.67 192/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 3 8 8 X 8.8.X [2.17.38.11] CATDGVGSTVKLMVMGPF#DFR out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'GGG' (3 nucleotides at position 61 to 63 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 133 to 133 in the user submitted sequence), (cause frameshift); gcctctggattcgtctttaacaactatgccatgggctgggtccgccaggctccaggggaaGGGggtttggagtggGgtctcatctattagtactagtggGgactaactcatactacgcagactccgtgaaggGgccggttcaccatctccagagacaattccaagcaagcgctttatctgcagatgaacagcctgagagccgaggacacggccgtttattactgtgcgacagatggagtagggtctactgtgaagttgatggttatgggcccttttggacttcaggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8925 JY8QFUQ01C74KW unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDY## out-of-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggcccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8926 JY8QFUQ01ACFWW unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*05 F 173 55.43 97/175 nt 8 7 X 8.7.X [1.17.25.X] null - No rearrangement found ctctgcattcaccttcagtagctacgacatgcactgggtccgccaagcaacaggaagaggtctggagtgggtctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +8927 JY8QFUQ01CEWZT unknown (see comment) Homsap IGHV3-11*01 F (see comment) 756 83.41 181/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaccctcagtgactacagtatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatacatcagccgaagtggaagtaatgtggaaactgcggactctgtgaggggccgattcaccgcctccagggacaccgccaataattcactgtttctgcggatgaatagcctgacagtcgaggacacggccctctattactgtgcgagagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8928 JY8QFUQ01CM7EV productive (see comment) Homsap IGHV3-30*08 F, or Homsap IGHV3-30*16 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGKAGHTHYGLDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctctgcattcaccttcagtagttatgctatgcactgggtccgccaggGccccaggcaaggggctagagtgggtggcagttatatcaaatgatggaaattataacgactatgcagactccgtgaaggggcgattcaccatttccagagacaactccaagaacacgctatttctacaaatgaatagcctgagagttgaggacacggctgtctataactgtgcgagaggaaaggctggccatacccactacggattggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8929 JY8QFUQ01DQTLP productive Homsap IGHV3-48*04 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +8930 JY8QFUQ01CHPZ5 No results +8931 JY8QFUQ01CY8AI productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtGactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8932 JY8QFUQ01DSBEC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 8 8 10 8.8.10 [1.17.38.11] CATWIQSHFDYW in-frame + cctctggattcacatttagtcactataccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagccattaatcaagatgccattaccacacactacccagactccgtgaagggccgcttcaccgtctccagagacaattccaagaacacactctatctgcaaatgagcagcctgagagccgacgacacggccgtatattattgtgcgacgtggatacagtctcactttgactattggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8933 JY8QFUQ01CW8PV productive Homsap IGHV3-30*15 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame + ctctggattcacctttagtagatattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttatatcatacgatggaagtagaagaatctacgcagactccgtgaagggccgattcaccatctccagagacacttccaagaacacggtgtatctgcaaatgagtagcctgagacctgaggacacggctgtgtattactgtgcgagagatgagctgccttgggatacaatagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +8934 JY8QFUQ01DI3HO productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +8935 JY8QFUQ01CQTPI productive Homsap IGHV4-39*02 F 834 86.82 191/220 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8936 JY8QFUQ01DAX0B No results +8937 JY8QFUQ01C113H productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'GTC' (3 nucleotides at position 73 to 75 in the user submitted sequence), (do not cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggctggGagtgggGTCagtctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8938 JY8QFUQ01CT1KY unproductive (see comment) Homsap IGHV3-66*02 F 953 93.95 202/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 X 8.7.X [1.17.38.11] CVGDRQKG*LFR#YW out-of-frame + stop codons cctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +8939 JY8QFUQ01CSIS8 No results +8940 JY8QFUQ01BC1NA productive Homsap IGHV4-61*02 F 951 92.73 204/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame + ctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +8941 JY8QFUQ01AM81W unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.17 200/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGYHGPFDS## out-of-frame + ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacacatactactcagactccgtgaggggccggttcaccatctccagagacaacgccaagaacacgatgtatctgcaaatgaacaccctgagagacgaggacacggccgtctatttctgcgcgaaaggttaccacggcccctttgactcttggggccggggcaaccctggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8942 JY8QFUQ01BX45F unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 900 90.78 197/217 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRHTAMERGDY## out-of-frame + ttctggatatgactttatcaactactggatcggctgggtgcgccagatgcccgggagaggcctggaatggatgggaatcatctttcctgatgactctgatgccagatatagtccgtccttccagggccacgtcaccatctcagccgacaagtccacaagcaccgcctacctggagtggagcagcctgaaggcctcggacaccgccatctactactgtgtgagacatacagctatggagaggggtgactactggggccccgggaaccctggtcaccgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8943 JY8QFUQ01BLWYE productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8944 JY8QFUQ01A50CS unknown (see comment) Homsap IGHV3-74*03 F 99 52.59 71/135 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons cctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8945 JY8QFUQ01BX688 productive Homsap IGHV3-7*01 F 960 93.18 205/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSAYFSTGYW in-frame - agcctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +8946 JY8QFUQ01BX57K No results +8947 JY8QFUQ01AH715 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 7 8 15 7.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8948 JY8QFUQ01BUQAY productive (see comment) Homsap IGHV4-38-2*01 F, or Homsap IGHV4-38-2*02 F 815 86.24 188/218 nt 84.4 184/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 9 7 15 9.7.15 [1.17.38.11] CAREGDGYIYKRSFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'CAC' (3 nucleotides at position 26 to 28 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'ACT' (3 nucleotides at position 95 to 97 in the user submitted sequence), (do not cause frameshift); tctctgacgactccatcagcagtggCACttactactgggAgttggatccggcagcccGccggggaaggctccggagtggattggccgcttctatACTattactgggcgcaccaactacaatccctccctcgagagtcgagtcaccataacaagggacgtgtccaagaatcagttctccctgagactgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagagagggggatggctacatctacaagaggtcttttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8949 JY8QFUQ01CGPB2 No results +8950 JY8QFUQ01A0HBK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDFFIGGYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +8951 JY8QFUQ01CL1S7 No results +8952 JY8QFUQ01A313H No results +8953 JY8QFUQ01A2FC1 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDNYGDYW# out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaagggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8954 JY8QFUQ01AY5WJ unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 623 75.68 168/222 nt 75.23 167/222 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [3.17.38.11] CARDSGSSEYTRYDAQDVW in-frame - stop codons Low V-REGION identity (75,68% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); ctctggattcagcgttaagttcgttatgggcatntaactggggtccgccaggctccatggggggggctggGagtgggtctcattcattaacagtattagtagttataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8955 JY8QFUQ01A4MJ5 productive Homsap IGHV4-39*03 F 929 91.36 201/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8956 JY8QFUQ01A21XY unproductive Homsap IGHV3-33*03 F 918 91.71 199/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD2-8*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDRGCTNGACYVADF## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaactattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggcccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8957 JY8QFUQ01AWUJ4 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARDCDSGECNFDYW in-frame - stop codons in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); tctgattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatCccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8958 JY8QFUQ01BON36 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtacatactggatgcactgggtccgccCaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8959 JY8QFUQ01BJJ62 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8960 JY8QFUQ01AD4BK No results +8961 JY8QFUQ01B4PD9 productive (see comment) Homsap IGHV3-48*01 F (see comment) 759 84.11 180/214 nt 83.64 179/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8962 JY8QFUQ01C09UG No results +8963 JY8QFUQ01CITN1 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttgggggAcaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggctgacggtgtcgtggaactcag +8964 JY8QFUQ01APN0I No results +8965 JY8QFUQ01DAEQZ unproductive Homsap IGHV3-48*02 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGEGDPFF##YYSGLDVW out-of-frame - in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtGaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8966 JY8QFUQ01BF5OD productive Homsap IGHV3-49*04 F 994 93.78 211/225 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 10 17 8.10.17 [2.17.38.11] CTRDNPPLRSLEWLPFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacgtttagagactattggatgagttgggtccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcaaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8967 JY8QFUQ01CW5KL No results +8968 JY8QFUQ01BE62D productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.21 206/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 97 of V-REGION: 'T' (1 nucleotides at position 199 to 199 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggGggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccTgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +8969 JY8QFUQ01BAGNX No results +8970 JY8QFUQ01B6HAI unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 620 93.01 133/143 nt 91.61 131/143 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 7 1 X 7.1.X [1.X.38.11] CVSDLAGQKGF## out-of-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01B6HAI ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 38 of V-REGION: 75 nucleotides (from position 27 in the user submitted sequence), (do not cause frameshift) cctcaggattcaccttcagtagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgCtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8971 JY8QFUQ01BKF4E productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +8972 JY8QFUQ01BZ6BK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 835 88.26 188/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [X.17.38.11] CAKEEGATGVYYVDHW in-frame + ggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgagtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8973 JY8QFUQ01BJNET unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 760 83.8 181/216 nt 83.33 180/216 nt 7 8 X 7.8.X [1.17.38.X] null + No rearrangement found stop codons Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) ctctggatccagtttcagtggtttggcgtgaactaggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccctgctccaggagcaccctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8974 JY8QFUQ01BO31O productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 653 77.52 169/218 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD3-3*02 F 3 9 7 12 9.7.12 [1.17.38.11] CARENIIREGLDRW in-frame + Low V-REGION identity (77,52% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) tgtctggtggttctactcgcactaaccattggtggaattgggtccgccagacccccgacaagggactggagtggattggagaagtctataagagtggacagaccaactacaacccgtcactccagagtcgcgttgacctcttcattgacaactccaggaatcagatctccctaaatatgagagatgtgaccgccgcggacacggccgtctattactgcgcgagagaaaacattattcgggagggccttgaccgctggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8975 JY8QFUQ01AF29Y productive (see comment) Homsap IGHV4-61*02 F 988 94.14 209/222 nt 93.69 208/222 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD5-18*01 F 3 10 7 18 10.7.18 [2.17.38.11] CARVRARSNSHPGHSWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagcagcagtaGgttactactcgacctggctccggcagcccgccggaaagggaccggagtggattgggcatatctatagtagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcggacacggccgtgtattactgtgcgagagtgagggcgcgcagtaatagtcaccccggccacagctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8976 JY8QFUQ01CC1IS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggctcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8977 JY8QFUQ01CCGG2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY# out-of-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaacttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8978 JY8QFUQ01AXGE4 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 999 95.85 208/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatggtgatgggactagcacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgttgtatttgcaactgagcagtctgagagccgaggacacggctgtgtatttctgtgcaagacccttgagtgggagttccagatcccccagcggctactggggccagggaacccgtggtcaccgtctcctccgcatccccgaccagctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8979 JY8QFUQ01AO96R unproductive (see comment) Homsap IGHV3-9*01 F 406 89.22 91/102 nt 87.25 89/102 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 7 X 16 7.X.16 [X.15.11.11] CAKDGSAIPVTGTYFEYW in-frame - stop codons in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 54 of V-REGION: 109 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) gattcaccttcatgattataccatgcactgggtccggcaagctccagggaagggcctggaatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8980 JY8QFUQ01BM95A unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 819 86.18 187/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8981 JY8QFUQ01CUJ4V No results +8982 JY8QFUQ01DFKC8 productive (see comment) Homsap IGHV4-55*03 P (see comment) 734 82.03 178/217 nt 81.57 177/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 9 7 15 9.7.15 [1.17.38.11] CARDQSVYTAGSYFDSW in-frame + Potentially, because of detected insertion/deletion however the closest V is a pseudogene Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); tctctggtgactccatgagtagcgacacgtggtggagctgggtccgccagacgccagagaagggactggaatggattggggagatcaatcaaagagggacgacctcctacaacccgtccctcaggagtcgagtcgtcctgtcagtgggcgagtccaaaaaGtcaattctccctgaggctgacctctgtgaccgccgcggactcggccatctattattgtgcgagagatcagtctgtctatactgcgggaagttactttgactcctggggccagggaacgctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8983 JY8QFUQ01DGQKI productive (see comment) Homsap IGHV3-7*01 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.37.11] CARTSSREITDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) ctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +8984 JY8QFUQ01API5M productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame + ctctggattctccgtcagtaattactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8985 JY8QFUQ01CEZIY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +8986 JY8QFUQ01AZJ58 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 937 91.78 201/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - gcctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +8987 JY8QFUQ01CRTME productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccagccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +8988 JY8QFUQ01DT4RC No results +8989 JY8QFUQ01CHMCE unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 514 73.0 146/200 nt 8 8 X 8.8.X [2.17.31.X] null - No rearrangement found Low V-REGION identity (73,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release agcctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtcatcgcctgcctggtccagggcttcttcccca +8990 JY8QFUQ01A4J3A No results +8991 JY8QFUQ01B04S9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8992 JY8QFUQ01DUB3R productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 800 86.05 185/215 nt 85.12 183/215 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CATVRHLGERIFDFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'C' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctgggggCcaccatgagtagtttctactggagctgggttcggcagTcccccagggaggggactggagtggattggatttgtttcttacagtgggcccaccaactacagcccctccctcaagagtcgagtcaacttatcactggacgcggccaacaaacagttctctttgcagctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +8993 JY8QFUQ01AZBUC unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLPFIVVVTGAFLGHFDY## out-of-frame - ttctggatacacgtttatgaattactggctcggctgggtgcgccagatgcccggcaaaggcctggagtggatggggatcatctttcctgctgactctgatgcccgatacagcccgtccttccaaggccaggtcaccatctcaatcgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacgccgccatatattactgtgcgagactcccctttattgtggtggtgactggtgcgtttttgggacactttgactattgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +8994 JY8QFUQ01DJQ1O unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CANEVGYCSSG# out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttaacatgtatgtcatgcactggttccgccaggttccagggaaggggctggagtgggtctcaactattcgtgcccgtggtgataggacacactacgcggactccgtgaagggccgcttcaccatctctagagacaattcaaaggacaccctgtatttgcaaatgtacagcctgcgagtcgaggacacggccgtctattactgtgcgaacgaagtcgggtactgtagtagtgggggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8995 JY8QFUQ01BREW3 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +8996 JY8QFUQ01BGJXT No results +8997 JY8QFUQ01B793Z unproductive Homsap IGHV3-30-3*01 F, or Homsap IGHV3-30-3*02 F (see comment) 411 80.0 104/130 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 1 X 5 X X.5.X [X.X.38.11] CARDDFYSSGITE#FGMDVW out-of-frame + Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtcactatgactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcgggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +8998 JY8QFUQ01DRB53 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 795 84.3 188/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 10 15 8.10.15 [1.17.38.11] CTTDSFHIAVHGVFDFW in-frame + Low V-REGION identity (84,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttctgcattcatgttcaacaaagcctggatgaattgggtccgccaggctccaggaaagggactggagtgggttggccgtattaaaagtaacggcgacggtgcgacagtcgactacgctgcacccgtgaaaggccgattcaccatctcaagagatgattcacagaataccctcttcttacaaatgagcagcctgaaagccgaggacacagccgtctattattgtaccacagatagcttccatattgcagtgcatggcgtctttgacttctggggccagggagccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +8999 JY8QFUQ01A70L0 productive Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9000 JY8QFUQ01BE4FQ No results +9001 JY8QFUQ01BQ190 productive (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F 311 85.71 72/84 nt 84.52 71/84 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 X X 20 X.X.20 [X.X.28.11] CAKDIRSVRDRGFSFGYGFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); tctggattcagagacaacCgccaagaactccctgtatctggaaatgagcagtctgagaantgaggacacggccctgtattattgtgcaaaggatattcgttccgtccgagatcgtggattcagctttgggtacggttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +9002 JY8QFUQ01CB1XG productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 896 90.37 197/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - cctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9003 JY8QFUQ01AA9ZQ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame - cgtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9004 JY8QFUQ01BB73D productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 714 81.78 175/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Low V-REGION identity (81,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcaccatcactcactactccatggcctgggtccgccaggctccggggaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcgcctcatcatctccagagacgaatccaagagtgagctgtatcttcggatgacgaaagtgaaagccgaagacgcggccgtatattactgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9005 JY8QFUQ01BJASR unproductive Homsap IGHV3-30*10 F (see comment) 712 80.82 177/219 nt 80.37 176/219 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [2.17.38.11] CSRGTTGTTDDSRLFQH## out-of-frame - Low V-REGION identity (80,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 157 to 157 in the user submitted sequence), (cause frameshift); gcctctggattcagcttcggcaattacgccatgcactgggtccgccaggctccaggcaagggcctagagtgggtggctgtcataaataaggctgggaagactaaacattatatagactccgtgaagggccgattcaacgtctccagagacaactccGcaaaaaacactctatttggagatgaataacgtgggagttgaggacacggctgtatattattgttcgagaggtaccacggggacgacagacgactcgaggttgttccaacactgggggccagggcgccctggtcaccgtttcgtcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9006 JY8QFUQ01AFT7Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccagttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9007 JY8QFUQ01CGS2N productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9008 JY8QFUQ01BF2UN productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.16.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaagggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9009 JY8QFUQ01B1W4F productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 933 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [2.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); agcctctacattcGccctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9010 JY8QFUQ01BGTX0 No results +9011 JY8QFUQ01BNXKI productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 874 89.04 195/219 nt 88.13 193/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift) gcctcctggattcaccCtttggttattatggcatggactggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9012 JY8QFUQ01A0NOK No results +9013 JY8QFUQ01B5RYC productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARDGEWELFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtaggtactggatgtactgGggcccgccaagctccagggaAaggggctggtgtgggtctcacgtattaagaatgatgggactaccgcgacctacgcggactccgtggagggccgattcagcatttccagagacaacgccaaggacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattattgtgcacgagatggggagtgggagctatttgactactggggccagggaaccctggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9014 JY8QFUQ01AJOMR productive (see comment) Homsap IGHV3-11*01 F (see comment) 688 80.09 173/216 nt 79.63 172/216 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-25*01 F 2 8 8 11 8.8.11 [1.17.37.11] CVRDRSRGIADPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 157 in the user submitted sequence), (cause frameshift) gtctggattcaccttcactgactattggatgagttgggtgcgcctgaccccagggaagggtctagaatgggtttcgttcataagtggaagtggcaatagtgtctggtatgcagactctgtgaagggccgattcattatctccagagacaacgccaaaatttagtctttttggacatgaacagcctgagagtcgaggactcggccatgtattattgtgtgagagaccgcagcaggggaatagcagatccttggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +9015 JY8QFUQ01AQMPE unknown (see comment) Homsap IGHV3-7*01 F 1036 96.8 212/219 nt 96.35 211/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9016 JY8QFUQ01B42GO productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9017 JY8QFUQ01DNMAA unproductive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARASTFYYDGSGYRD#FDIW out-of-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9018 JY8QFUQ01A4MUK productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 858 87.44 195/223 nt 86.55 193/223 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [3.16.38.11] CVRAGFGELSGFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 21 to 22 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) ccaggcctcctggattcaccCTttgggttattatggcatggactgggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactactggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9019 JY8QFUQ01CTB18 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtacttactactggacatGggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9020 JY8QFUQ01CPRY6 productive Homsap IGHV3-7*01 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-3*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARHKTISGVVIMGAFDYW in-frame + ctcggaattcacttttggtagtcactggatgagttgggtccgccaggctccagggatgggactggagtgggtggccaacataaaaacagatggaagtgagacacactatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcactgtatttgcaagtggacagcctgagagccgaggacacggctgtttattactgtgcgaggcacaaaacaatttctggagtggttattatgggagcatttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9021 JY8QFUQ01CRFXK productive Homsap IGHV1-2*02 F 822 87.38 187/214 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [0.17.38.11] CAKHPLRSTSGHSYLDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggatacatattcaccgacttttatatacactgggtgcgacaggctcctggacaagggcttgagtggatgggatccatcaatcccaacagtggtgtcacaacctacgaagagaagtttcggggcagggtcaccatgaccagggacacgtccatcactacagcctacatggaactgacaagccttacatcagacgacacggccgtatattactgtgcgaaacatcctcttcgatcaacaagtggacattcctacttagattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9022 JY8QFUQ01BB3P5 productive Homsap IGHV3-9*01 F 945 93.09 202/217 nt Homsap IGHJ1*01 F (see comment) 143 75.0 39/52 nt Homsap IGHD4-17*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARLPGDYGSRW in-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaactttgataaatatgacatgcactgggtccgacaagctccagggaagggcctggagtgggtctcaggtattaagtggaatggcggtcgcgtcggctatgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagacctgaggacacggccttctattactgtgcaagactccccggtgactacgggtctcgttggggccagggaaccctcatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +9023 JY8QFUQ01CE17F No results +9024 JY8QFUQ01CBGI5 No results +9025 JY8QFUQ01BLWWD productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 7 8 11 7.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) tctctggattcacctttagtaggtttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9026 JY8QFUQ01C45JT productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +9027 JY8QFUQ01BZOH1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9028 JY8QFUQ01ASH1A unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F (see comment) 784 84.47 185/219 nt 83.56 183/219 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-9*01 F 3 9 7 X 9.7.X [1.16.38.11] CARILDGYFFD#PG out-of-frame - Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) tctctggtggctccatcgacactcaaattactactggggctggattcgccagccccagggacgggactggagtgggttggcagtgtccgctatggcgagagcacctattacaacccgaccctcaaaagtcgactcaccatatccatagacacgtccaggagccagttatccctgagactgagttctgtcaccgccgccgacacggcagtttactactgtgcgaggatcttggatggttacttcttcgacccctgggggccagggaacccacgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactactttccgaaccggtgacggtgtcgtggaactcag +9029 JY8QFUQ01A1IEL No results +9030 JY8QFUQ01BKVBB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9031 JY8QFUQ01CTMCO productive Homsap IGHV3-43*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-8*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDRIGSLYYFDHW in-frame + ctcaggattcacatttgctgaatataccatgcactgggtccgtcaagttccggggaagggtccggagtgggtctctcttattagttgggatggtggcagcacatactatgcagactctgtgaagggccgattcaccatctccagagacaacagcaaggactccctgtatctgcaaatgaacagtctgagaactgaggacaccgccttgtattactgtgcaaaagataggattgggtccttgtactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9032 JY8QFUQ01CGZQ8 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 153 53.89 97/180 nt 8 7 X 8.7.X [1.17.26.X] null + No rearrangement found ctctggattcaacttcggtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9033 JY8QFUQ01AATLY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 977 94.5 206/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - cctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9034 JY8QFUQ01C28D8 productive Homsap IGHV1-8*01 F 939 93.46 200/214 nt Homsap IGHJ6*02 F 112 64.52 40/62 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [0.17.38.11] CARGYGYPNYYHYAMDVW in-frame + tggataccccttcgacagttatgatatcagctgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaacagtgggaatacagcctatgcacagaagttccagggccgagtcacgatgaccagggacacctccacaagcacagcctacatggaggtgagcagcctcagatctgaggacacggccgtctattactgtgcgcgcggttatggctacccaaactactaccactacgctatggacgtctggggccaagggttccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +9035 JY8QFUQ01CVTSB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9036 JY8QFUQ01BV1VR productive (see comment) Homsap IGHV4-61*02 F 892 89.95 197/219 nt 89.04 195/219 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [1.17.37.11] CARDPRVICSGGSCRSSAMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 117 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 160 in the user submitted sequence), (cause frameshift) tctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaaccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagaccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +9037 JY8QFUQ01C2XX8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 874 89.04 195/219 nt Homsap IGHJ4*01 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [2.17.38.11] CVRDRDFLWGSYRLQLEYW in-frame - gactctggattcagatttagcagctatggcatgagctgggtccgccaggctccaaaaaaggggctggagtgggtctcaggaattagtgcgaatggtggtagtataaattatgcagactccgtgaagggccgattcatcatctccagagacaattccaagaacacattgtttctgcaaatgaatagcctgagagccgaagacacggccgtatattactgtgtgagagatcgcgatttcctgtgggggagttatcgtcttcaacttgaatattggggccaaggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9038 JY8QFUQ01BH3ZC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9039 JY8QFUQ01DWD9J productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 13 8.8.13 [1.17.38.11] CARGGGGKSIPLDNW in-frame - cgtctggcttcacgttcagtagttatggcatgcaatgggtccgccaggctccaggcaaggggctggagtgggtggcagttatttggtatgatggaagtaataaatattatgcagactccgtgaagggccgattcgacatctccagagacaattccaagaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatgtaccattgtgcgagaggcggcggtggtaagtccattccacttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9040 JY8QFUQ01AN2RA No results +9041 JY8QFUQ01AF5AE No results +9042 JY8QFUQ01AF4Z9 productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 678 79.91 171/214 nt 79.44 170/214 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) ctctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9043 JY8QFUQ01CE9R1 No results +9044 JY8QFUQ01DAQCO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 76 of V-REGION: 'G' (1 nucleotides at position 133 to 133 in the user submitted sequence), (cause frameshift); ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttGcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9045 JY8QFUQ01B433C productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1007 96.74 208/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAREDGSGRRHFDYW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccaggaaagggactggagtggattgggtatatcttttacactgggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9046 JY8QFUQ01AE4R0 No results +9047 JY8QFUQ01DPTXI unproductive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F (see comment) 592 93.94 124/132 nt 93.18 123/132 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 X X 8.X.X [2.3.31.11] WCEGGW*R##LDYW out-of-frame - stop codons Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 40 in the user submitted sequence), (do not cause frameshift) acctctggattcacctttagtaaccattggatgaactggggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactggtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctccagcatccccgaccagccccaaggtcttcccggctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9048 JY8QFUQ01ASZT4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcttggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9049 JY8QFUQ01AXXCO unproductive Homsap IGHV3-30*04 F, or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*03 F 900 90.32 196/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGGGGG#AFDIW out-of-frame + ctctggattcaccttcaggagttatgatatgcactgggtccgccagactccaggcaaggggctggagtgggtggcagtgatattatatgatggaagaaaacaattttacgcagagtccgtggagggccgattcaccatctccagagacaactccgggaacacactggatctgcaaatgaacagcctgagacctgaggacacggctgtctattactgcgcgagagggggaggtgggggtctgcttttgatatttggggccaagggacaagggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9050 JY8QFUQ01AW868 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 687 80.37 172/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARQHFDRGDSGRWLDPW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AW868 ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggctcaccttcacgacttacagcatcacctgggtccgccaggctccggggaagggactggagtggatttcatcaatcagtagcagaggcgagatgatctatggagagtctgtgaagggccggttcaccatctctagagacaacgccactgattcagtgtctctgcagatgaacagtctcagagacgaagacacggctgtgtattattgtgcgagacagcactttgaccgcggtgactccggaaggtggctcgacccctggggccaaggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9051 JY8QFUQ01CZJLE productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 696 80.84 173/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [1.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame + Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9052 JY8QFUQ01ADUHM productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcCccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaccggtgacggtgtcgtggaactca +9053 JY8QFUQ01CRC3J No results +9054 JY8QFUQ01AYGZP productive (see comment) Homsap IGHV1-3*01 F 880 90.61 193/213 nt 89.67 191/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.37.11] CARDGYRSGNGADYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 77 of V-REGION: 1 nucleotides (from position 133 in the user submitted sequence), (cause frameshift) tggatacagcttcactaactacaatatccattgggtgcgccagGgcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcacatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9055 JY8QFUQ01B1YPU No results +9056 JY8QFUQ01ALL88 productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARDRRPLREFDCW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 84 of V-REGION: 'C' (1 nucleotides at position 155 to 155 in the user submitted sequence), (cause frameshift); ctctggattcaccctctccagctatgctatgcactgggtccgccagtctcccggcaaggggctagagtgggtggcagctatttcatatgatggaagtaaaatatattacgcagactccgtgaggggccgcttctccatctccagagacagttccCaagaacactctgcatttgcaaatggacagcctgagacctgaggacacggctacatattactgtgcgagagatagacggccacttagggagtttgactgttggggccagggaaccccggtcgccgtctcctcggcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9057 JY8QFUQ01BIEJY productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 912 92.06 197/214 nt 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 12 8.8.12 [0.17.38.11] CARGRGYGSYADHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagctactatttgcactgggtgcgacaggCcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagtgacgcctccataaccacagcctacatggaactgagcaacctgaaatctgacgacacggccgtgtattattgtgcgaggggccgagggtacggaagttacgctgaccactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9058 JY8QFUQ01DVYNM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggGggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9059 JY8QFUQ01DMVHW productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 836 87.91 189/215 nt 86.98 187/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 7 8 17 7.8.17 [1.16.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) ctctggattcagtttagtacacatggcatgaactgggtccgccaggctccagggaagggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9060 JY8QFUQ01CEI6I productive (see comment) Homsap IGHV4-39*02 F 947 91.86 203/221 nt 91.4 202/221 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [2.16.38.11] CARRYSWNYERFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gtctctggtgactccatcagtactaataattactactgggcctggatccgccagccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9061 JY8QFUQ01CZDGQ productive Homsap IGHV3-7*01 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDPYKPGSGNPGFDYW in-frame + ctctggattcacctttagtgactatttgatgacttgggtccgccaggctccaggaaagggactggagtgggtggccaacataaaagaagatggacttgctacattctatgtggactctgtgagggaccgattcaccatctccagagacaacgccaagaactcactttatttgcaaatgaattacctgagagtcgaggacacggctgtttattattgtgcgagggatccctataaacctggttcgggcaatccgggctttgactactggggccagggagcgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +9062 JY8QFUQ01BIEI3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + ctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9063 JY8QFUQ01A94FS productive Homsap IGHV3-9*02 F 886 90.28 195/216 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + tccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaggatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc +9064 JY8QFUQ01BF2YK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9065 JY8QFUQ01BLF36 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 733 82.41 178/216 nt Homsap IGHJ3*01 F 83 62.0 31/50 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDKAGFTLHAFDVX in-frame + Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcgactttgccagccacgccatggcttgggtccgccggactccaaggaagggcctggagtgggtctcaggcataagtagtagtggtggaaccacgtattacgcagacttcgtgaagggccgcgccactgtctccagagacaattccgagaacacagtgtctctggaactccacagcctgagagccgatgacacggccatatattattgtgtgaaggacaaagcgggcttcaccctccatgcttttgatgtcnggggccgagggacggtgtcactgtttcttcaacatccccgaccagccccaaggctcttcccgctgagcctctgcagcaccctagccagatgggaacgctggtcgatcgccctgcctggnccagggcttcttcccccatgga +9066 JY8QFUQ01BECCF No results +9067 JY8QFUQ01AT6SD productive (see comment) Homsap IGHV4-39*07 F (see comment) 788 84.86 185/218 nt 84.4 184/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 9 7 15 9.7.15 [1.17.38.11] CARAVLDNAWPIYYDFW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (9 AA in JY8QFUQ01AT6SD ; 10 AA in Homsap_IGHV4-39*07), and low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 171 to 171 in the user submitted sequence), (cause frameshift); tgtctggtggctccatcaccacttggcattactggggctggatccgccagcccccaggggagggtctggaatggattggaaatgtctatcataatggcaatatcgcctatagcccgtcgcagaggagtcgaatcaccatatcagtagacacgtccaggaaccagttctccCctgaagatgacctctgtgaccgccgcggacacggctgtctattactgtgcgagggctgttcttgacaatgcctggcctatatattatgacttttggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9068 JY8QFUQ01CPK0C No results +9069 JY8QFUQ01DDZWF No results +9070 JY8QFUQ01DB3P3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1085 100.0 218/218 nt 98.62 215/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 7 8 18 7.8.18 [2.16.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 28 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) agcctctggattcaccGtttagcagctagccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9071 JY8QFUQ01BX6QP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9072 JY8QFUQ01CEN22 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 103 52.99 71/134 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9073 JY8QFUQ01BNIV0 No results +9074 JY8QFUQ01BIUUG productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1105 100.0 222/222 nt 98.65 219/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 3 8 10 12 8.10.12 [1.16.37.11] CTKCSVTIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 163 in the user submitted sequence), (cause frameshift) cttctggattcacctttGggtgattatgctatgagctggttccgccaggctccaggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9075 JY8QFUQ01CN1QR productive (see comment) Homsap IGHV3-72*01 F 956 92.76 205/221 nt 91.86 203/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.16.38.11] CITSFGGRSLAYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 182 to 182 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 54 of V-REGION: 2 nucleotides (from position 75 in the user submitted sequence), (cause frameshift) ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttgcgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatTgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgggagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9076 JY8QFUQ01DBOA7 No results +9077 JY8QFUQ01C0VWU productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 861 87.73 193/220 nt 87.27 192/220 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 10 7 12 10.7.12 [1.16.38.11] CARQRYYESDGQTW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) tctctggtggctccatcaccggaagtagttattattggggctggattcgccagtcccagggaaggggctggagtggattggaagtatgtattacactgggagcaccgactacaacccgtccctcaagagtcgggtcacgatatccgcagacaagtcgaagagccaggtctacctgaagttggactctgtgaccgccgcagacacaggtgtttattactgcgcgagacaaaggtactatgaaagtgatggccaaacctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +9078 JY8QFUQ01DGH8W unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9079 JY8QFUQ01BAD7L unknown (see comment) Homsap IGHV3-72*01 F 106 53.44 70/131 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +9080 JY8QFUQ01BRJZV No results +9081 JY8QFUQ01DBC2M productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9082 JY8QFUQ01C2QO4 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 948 91.93 205/223 nt 91.48 204/223 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-3*01 F 2 8 10 15 8.10.15 [1.17.38.11] CTTDRRGSDIPPQFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggatttagtttcaataacgcctggatgagctgggtccgccaggctccagggaaggGggctggagtgggttggccgtattaaaagcaaagctgatggtggggcggcagactacggtgcacccgtgagaggcagattcaccatctcaagagatgattcaagaggcacggtgtctctgcaaatgagcagcctgaaaaccgaggacacagccatctattattgtaccacagataggaggggttcggatattccacctcaatttgactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9083 JY8QFUQ01ASCP3 No results +9084 JY8QFUQ01DV802 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 701 80.93 174/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [1.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame + Low V-REGION identity (80,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9085 JY8QFUQ01COEXB unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 116 54.14 72/133 nt 8 8 X 8.8.X [1.17.9.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +9086 JY8QFUQ01CD0PS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9087 JY8QFUQ01CHBEX productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9088 JY8QFUQ01DEVGU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 187 86.0 43/50 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgttcctcag +9089 JY8QFUQ01BEW4I unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 912 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 7 8 X 7.8.X [1.17.38.11] CARGHSYYVSSGPDY## out-of-frame - in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) ctcggattcaccttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggantgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactgggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggctt +9090 JY8QFUQ01BJUQ6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 593 78.06 153/196 nt 77.55 152/196 nt 8 8 X 8.8.X [1.16.31.X] null - No rearrangement found Low V-REGION identity (78,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggcccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9091 JY8QFUQ01B9YJO No results +9092 JY8QFUQ01A8VXJ unproductive Homsap IGHV3-9*01 F 878 89.45 195/218 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD5-12*01 F 2 8 8 X 8.8.X [1.17.38.11] CARTYGDHD#MDVW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tctctggattcacctttgatgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtattagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcatcacatccagagacaatgccaagaactccatctatttgcaaatgaacagtctgagagatgacgacacggccttctacttctgtgcaaggacttacggcgaccatgacgaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9093 JY8QFUQ01AF3VA unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 472 71.07 140/197 nt 8 7 X 8.7.X [1.17.32.X] null - No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AF3VA ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (71,07% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9094 JY8QFUQ01BMMMW productive Homsap IGHV3-33*04 F (see comment) 703 80.37 176/219 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [2.17.38.11] CARDILDYW in-frame - Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcatttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9095 JY8QFUQ01B6ZW6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccggaaccaggtgacggtgtcgtggaactc +9096 JY8QFUQ01CGNDO No results +9097 JY8QFUQ01CWXDQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGPHQYYFDYW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9098 JY8QFUQ01DWBZW No results +9099 JY8QFUQ01CJDMN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 861 88.18 194/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - agcctctggattcacctttaccgcctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9100 JY8QFUQ01A5NLU productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctCcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9101 JY8QFUQ01BMH1M productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 834 86.82 191/220 nt 86.36 190/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [2.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGcctcgccgacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9102 JY8QFUQ01BU44K No results +9103 JY8QFUQ01AU15Y productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 845 88.37 190/215 nt Homsap IGHJ2*01 F 175 81.13 43/53 nt Homsap IGHD3-9*01 F 2 8 7 12 8.7.12 [1.17.38.11] CAREATYYDAFDVW in-frame + tctctggcggctccatcgggagttactactggacctggatccggcagtctccagggaaggggctggagtggattggatatagccacagcagtgggaaaaccaattataatccttccctcaagagtcgagtcaccatatcaatagacacgtccaagaaccagttctccctgcagctgacctctgtgaccgctgcggacacggccatatattcctgtgcgagagaagcaacttactatgatgccttcgatgtctggggccgtggcacccaagtcagtgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9104 JY8QFUQ01A0HOP productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD1-26*01 F 3 10 6 15 10.6.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift) ctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +9105 JY8QFUQ01CUTS1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 783 84.79 184/217 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CAREEWDNGGFGAW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgacttcacttactactggatgcactgggtccgccaagttccagggcaggggctcgtgtgggtcgcacgtattgggattgttggtggtaaagcagactacgcggacgccgtaaagggccgtttcaccatctccagagacaacacaaggaagactctgtatctacaaatgaacagtctgcgacccgaggacacggcggtgtattactgtgccagagaggaatgggacaacggtggtttcggggcctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +9106 JY8QFUQ01AYAJQ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 408 87.62 92/105 nt 86.67 91/105 nt 8 8 X 8.8.X [1.16.1.X] null - No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 48 in the user submitted sequence), (do not cause frameshift) gctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggagggggctggagtgggtctcagccattagtggcagtggtagtcggacatatt +9107 JY8QFUQ01DCOGY No results +9108 JY8QFUQ01CXAIJ productive Homsap IGHV3-11*01 F (see comment) 769 84.26 182/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9109 JY8QFUQ01CXVP1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 864 88.94 193/217 nt Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD3-16*01 F 2 8 8 15 8.8.15 [1.17.38.11] CATQNYEGGAPFWFDPR in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtagaaacagtatgaattgggtccgccaggctccagggaaggcgctggagtgggtcgcaggcattagtagtagtggtacttatatagattacgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtctctgcaaatgaacagcctgaggggcgaagacacggcgatttactactgtgcgacccaaaactacgaagggggggctcccttttggttcgaccccaggggccagggaacccgtggtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagactgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9110 JY8QFUQ01C0FOR unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 172 94.74 36/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcacctttggttattatggcatgagctggg +9111 JY8QFUQ01AJ1VA productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATDDSNGWDEVADYW in-frame + ctctggattcaccttcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +9112 JY8QFUQ01BDB92 unproductive Homsap IGHV3-9*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-6*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKSGTYSSSSGHFDL## out-of-frame + ctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccaagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9113 JY8QFUQ01DITNB No results +9114 JY8QFUQ01DPMX1 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcagtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9115 JY8QFUQ01BYF7R productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*08 F 872 89.77 193/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 11 8.7.11 [1.17.38.11] CARGPSGSGFDLW in-frame - tctatggtgggtccttcagtggttactactggagctggatccggcagtccccagggaagggactggaatacattgcaactatctatggcagtagaaccaccaactacaacccctccctcaagagtcgagtcaccatatcagtggacacgcccaggaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtattttactgtgcgaggggtccctccgggtccggatttgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9116 JY8QFUQ01C2W90 No results +9117 JY8QFUQ01AGVXF No results +9118 JY8QFUQ01A64VB productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 929 91.4 202/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 10 7 11 10.7.11 [1.17.38.11] CARSYGFSRFDPW in-frame + tctctggtggctccatcaccagtagtctttaccgctggggctggatccgccagtccccagggaagggcctggagtggatagggaatatcttttatggtgggaccacctactacaacccgtccctcaagagtcgagtcaccttatccatagacacgtccaagagccagttctccctgaagctgtcctctgtgaccgccgcagacacggctctatattactgtgcgagatcgtacggtttctctcggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +9119 JY8QFUQ01AKBBL productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9120 JY8QFUQ01DB70M productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.37.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 194 in the user submitted sequence), (cause frameshift) ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggcccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9121 JY8QFUQ01BA1NX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1040 97.71 213/218 nt Homsap IGHJ6*02 F 121 66.13 41/62 nt Homsap IGHD3-22*01 F 2 8 8 27 8.8.27 [1.17.38.11] CARDSDGQTQGDGRGYYYISFYYHGMDVW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcatccattagtagtactagtaatcacatattctacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattccgacggacagacgcagggagatggtcgtggttattactacatttccttctactaccacggtatggacgtctggggccaagggtaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag +9122 JY8QFUQ01CWR7Q productive (see comment) Homsap IGHV3-48*03 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.16.38.11] CAKDKSAAWYAYFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 53 of V-REGION: 2 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagttctcccatgaactgggtccgccaggctccagggaggggcgtggagtggttcatacattagtggtagtggtactaccatgtattacgcagactctgtgcagggccgattcaccgtctccagagacaatgccaagaacttactgtatctgcaaatgaacagcctgagagccgaggacacggctttttattattgtgcgaaagataagagcgctgcctggtatgcctactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9123 JY8QFUQ01DE33S productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 947 92.31 204/221 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD6-19*01 F 1 10 7 10 10.7.10 [1.17.38.11] CAAYDSGWYKHW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tctctggtggctccgtcaacagtggtgattactactggacctggatccgccagcaccctgggaagggcctggagtggattggatacatctattacagtgggagcacttactacaatccgtccctggagagtcgagttaccatatcaatagacatgtctaagaaccagttctccctgaaagtgagctctgtgactgccgcggatacggccgtgtatcattgtgcggcgtatgacagtggctggtacaaacactggggccagggaaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcgtngcatgcctggttccaggggccttcttcccc +9124 JY8QFUQ01CH6U0 unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F or Homsap IGHV7-81*01 ORF 139 58.88 63/107 nt 8 8 X 8.8.X [0.17.2.X] null - No rearrangement found cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9125 JY8QFUQ01BRYWA productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 90 to 95 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9126 JY8QFUQ01BK7KR productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9127 JY8QFUQ01BC2IW productive Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARDPRVICSGGSCRSSAMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaacccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagaccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +9128 JY8QFUQ01B530R productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9129 JY8QFUQ01A5TIW unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccttggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9130 JY8QFUQ01BF6VT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9131 JY8QFUQ01CHO3Z productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9132 JY8QFUQ01AR4BT No results +9133 JY8QFUQ01AC3GP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggGggccggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9134 JY8QFUQ01BNQW6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9135 JY8QFUQ01AMWRD productive (see comment) Homsap IGHV3-30*01 F 896 90.37 197/218 nt 89.45 195/218 nt Homsap IGHJ4*03 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 2 8 8 11 8.8.11 [2.16.38.11] CAREWAASHFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'AA' (2 nucleotides at position 53 to 54 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 31 in the user submitted sequence), (cause frameshift) gccgctggattcaccttcagtggctttgcttgcactggctccgccaggctccAAaacaagggggctagagtgggtgggatttacatcatttgatgggagtaacagagactacgcagactccgtgaagggccgattcacgatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagacctgacgacacggctgtatattactgtgcgagagagtgggcagccagtcactttgaccactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9136 JY8QFUQ01CN0HY productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9137 JY8QFUQ01C8V7V unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1070 97.77 219/224 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 3 8 10 X 8.10.X [1.17.38.11] CTTDGGISS#FDFW out-of-frame - cctctggattcaccttcagtaacgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaaactgctggtgggacaacagactacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcaaagaacacgctgtatttgcaaatgaacagcctgaaaaccgaggacacagccgtgtattattgtaccacagatgggggcatctcgtcccctttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9138 JY8QFUQ01A6FUM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 895 90.74 196/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + tccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9139 JY8QFUQ01CYXIA unknown (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found ctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttcggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc +9140 JY8QFUQ01BG50Z No results +9141 JY8QFUQ01CM1E0 unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9142 JY8QFUQ01DGV60 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 771 99.36 156/157 nt 98.09 154/157 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*03 F 3 X 8 18 X.8.18 [X.6.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); tctggagtgggtctcagcGtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagGaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9143 JY8QFUQ01AD8J3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 12 8.8.12 [1.17.38.11] CAGYYPPSSPFDYW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattagcggtagtggtgatagcacatactacgcagactccctgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgggagccgaagacacggccgtatatcgctgtgcaggctattatcccccaagtagcccctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9144 JY8QFUQ01DSL9S No results +9145 JY8QFUQ01CGMXU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9146 JY8QFUQ01BS1HE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-19*01 F 1 7 8 10 7.8.10 [1.17.38.11] CMNELGYCSGGG in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) ttctggattcactttagcagtcatatgatgagttgggtccgccaggctccagggaagggactggaatgggtctcaagtattcgtgccagtggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgctgtatttgcaaatgtacagcctgagagtcgaggacacggccttatattactgtatgaacgaactcggatattgtagtggtggggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9147 JY8QFUQ01CS9KQ productive Homsap IGHV3-72*01 F 884 89.14 197/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 3 8 10 9 8.10.9 [0.17.38.11] CAVAAPPYDGW in-frame - ctggattcaccttaagtgacttctacatggactggctccgccaggctccagggaaggggctggagtgggttggtcgcagtagaaacaaagctaatggttacagtacacaattcgccgcatctgtgatgggcagattcaccatctcaagagatgactcaaagaatttactatatctacaaatgagcagcctgaaaaccgaggacacggccatttattactgtgctgtcgcagcccccccttatgacggctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9148 JY8QFUQ01DQWX2 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F 121 54.48 73/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons ctctggattcacgtttagtgactactacatgacctggattcgtcaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9149 JY8QFUQ01B6N9B unknown (see comment) Homsap IGHV3-48*01 F 968 94.04 205/218 nt 93.58 204/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in FR3-IMGT at codon 94 of V-REGION: 'C' (1 nucleotides at position 186 to 186 in the user submitted sequence), (cause frameshift); tctctggtgggtccttcagtggttacttctggaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcCctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaacctcag +9150 JY8QFUQ01APC76 No results +9151 JY8QFUQ01CUB5Z productive (see comment) Homsap IGHV3-66*02 F, or Homsap IGHV3-66*03 F 871 90.14 192/213 nt 89.67 191/213 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 7 11 8.7.11 [1.17.38.11] CARDGRGGDLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); tctgggttctccgtcagtttcaactacatgagctgggtccgccaggctccagggaaggggctggagtGgggtctcagttatctatgccgatggaagtacattctatgcagactccgtgaagggccgattcatcatctccagagacaattcaaagaacacgctcaatcttcaaatgaatagtttgagagttgacgacacggctgtgtattactgtgcgagagatgggcgcggcggtgaccttgactcctggggccagggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9152 JY8QFUQ01DEXKU productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1004 95.87 209/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +9153 JY8QFUQ01C3IIM productive Homsap IGHV4-39*02 F 834 86.82 191/220 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9154 JY8QFUQ01DAMHL productive (see comment) Homsap IGHV4-59*03 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 89 to 94 in the user submitted sequence), (do not cause frameshift); ctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9155 JY8QFUQ01CCKZP unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 468 68.2 148/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (68,20% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9156 JY8QFUQ01CA1G6 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1007 96.74 208/215 nt 95.81 206/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAREDGSGRRHFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttactactggagctggatccggcaGgcccccaggaaagggactggagtggattgggtatatcCttttacactgggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +9157 JY8QFUQ01BHYP9 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 800 85.25 185/217 nt 83.87 182/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [2.16.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift)in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) cctccgggagttcaccttagtagttctggatncactggggtccgcaagttccagggagggactggtntgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +9158 JY8QFUQ01AECKB No results +9159 JY8QFUQ01CFKT7 No results +9160 JY8QFUQ01BPU9T No results +9161 JY8QFUQ01BJDXD productive (see comment) Homsap IGHV3-23*05 F 841 87.96 190/216 nt 87.5 189/216 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD3-9*01 F 2 8 7 18 8.7.18 [2.17.38.11] CVKVAGDYRTPNYGWHFDLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 97 in the user submitted sequence), (do not cause frameshift) gcctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactggatctgcaaatgaatagcctgagaggcgaagacacggccgcatattactgtgtgaaagtggccggtgactatagaactcccaactacggctggcacttcgatctctggggccgaggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +9162 JY8QFUQ01B85GD No results +9163 JY8QFUQ01DSG6M productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9164 JY8QFUQ01BTLKF productive (see comment) Homsap IGHV3-48*01 F 979 95.77 204/213 nt 95.31 203/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [0.16.38.11] CAKDGPGGGWYAEQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) tggattcaccttcagtagatatagtatgaactgggtccgccaggctccaggaaaggggctgagtgggttgcatacattagaagtagcagtagtgtcatatactacgcagactctgtgaagggccaattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaagatgggccggggggtggctggtacgctgagcagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9165 JY8QFUQ01BLRNU unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDLRGSTMASD#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaaggggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc +9166 JY8QFUQ01C5HJ8 productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATDDSNGWDEVADYW in-frame + ctctggattcaccttcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggtgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +9167 JY8QFUQ01C9SDI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 698 80.28 175/218 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGLGLNAVYAFDVW in-frame - Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcgcttttggagattatgccatgaactgggtccgccaggccccagggaagggactggagtgggtctcaggtttgagcggtagaggcgtcagcaaatattatgcagactccgtgaggggccggttctccatttccagagacaactccgggagcgaggcagtccttcaaatgagcagcctgagagtcgaggacacggccacttactactgtgcgaggggcctagggcttaatgctgtctacgcatttgacgtctggggacaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9168 JY8QFUQ01A4BFS productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 936 92.63 201/217 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARGSRDVGDAFDVW in-frame - gtctggattcaccttcactaaccatgtcatgcactgggtccgccaggctccaggcaaggggctggagtggttggcaattatatggtatgatggcagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgattgatctgcaaatggacagcctgagagtcgaagacacggcggtgttttattgtgcgagagggagccgggacgtcggggatgcttttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9169 JY8QFUQ01C5HGU unknown (see comment) Homsap IGHV4-61*02 F 888 89.55 197/220 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9170 JY8QFUQ01A0RJS productive (see comment) Homsap IGHV3-7*01 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 8 14 7.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) cctctggattacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9171 JY8QFUQ01CVXL1 No results +9172 JY8QFUQ01DQG9K productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9173 JY8QFUQ01BF2HZ unproductive (see comment) Homsap IGHV3-9*01 F 973 94.06 206/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [2.16.38.11] CAKSGTYSSSSGHFDLW in-frame - stop codons in CDR1-IMGT at codon 36 of V-REGION: 'AG' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift) agcctctggattcaacctttaataAGttatgccatgcactggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9174 JY8QFUQ01B1TFE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9175 JY8QFUQ01CPB9D No results +9176 JY8QFUQ01AXV08 unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9177 JY8QFUQ01AXREM productive Homsap IGHV3-48*01 F 810 86.18 187/217 nt Homsap IGHJ6*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 1 8 8 8 8.8.8 [1.17.38.11] CVRGAGLDVW in-frame + ctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaggggctggagtgtgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctggacgtctggggccaagggaccacggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +9178 JY8QFUQ01CQBLN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 952 92.34 205/222 nt 91.89 204/222 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [3.17.38.11] CAKAPYGEDAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift); gcagcctctggattcacctttagcgactatgCccatgaactgggtccgccaggctccagggaaggggctacagtgggtctcatctatcagtgatagtggtggttccacatactccgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacgctttatctgcgaatgagcagcctgagagccgaggacacggccatatattactgtgcgaaagcaccatacggtgaagatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9179 JY8QFUQ01CWGHM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc +9180 JY8QFUQ01ARRSG No results +9181 JY8QFUQ01DVMRY productive (see comment) Homsap IGHV3-11*01 F 1008 96.31 209/217 nt 95.85 208/217 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD2-2*01 F 2 8 8 12 8.8.12 [1.16.38.11] CAVDCTSISCNGDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 38 in the user submitted sequence), (cause frameshift) cctctgggttcaccttcagtgactactacatgagctgatccgccaggctccagggaaggggctggagtggctttcatatattagtagtgctggtagtaccatatactacgcagactctgtgaggggccgattcaccatctccagggacaacaccaagaactcactgtatctgcaaatgaacagcctgagggccgaggacacggccgtgtattactgtgcggtagattgtactagtatcagctgcaacggagactggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9182 JY8QFUQ01CHFYS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 707 80.73 176/218 nt 80.28 175/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARYRVGDSLYYGLDGW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 59 of V-REGION: 'ACT' (3 nucleotides at position 90 to 92 in the user submitted sequence), (do not cause frameshift); cctctggattcattttagaaaattttgccatgagttggctccgccaggcaccagggaaggggctggaatgggtctcgactatcagcagcACTagtggtgacacggcatattactcagactccgtgaggggccgcttttccatctccagagacaactccaagagcactctgttcttgcagatgaacagcctgagtgccgaagacacggccatttactactgtgcgagataccgtgtgggtgacagtctctactacggtttggacggctggggccaagggaccacggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9183 JY8QFUQ01AMX59 productive (see comment) Homsap IGHV3-33*03 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift) cgtctggattGcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9184 JY8QFUQ01C6TKI No results +9185 JY8QFUQ01AK8PN productive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9186 JY8QFUQ01A0UZS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 915 90.91 200/220 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 1 8 8 12 8.8.12 [2.17.38.11] CGKQLGAHKGADYW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) agcctctggattcacctttagtagttctggcatgtattgggcccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatgccacaaattacgcagactccgtgaagggccggttcaccatctccagagacaactccatgaacacactgtatctgcaaatgaacagcctgggaaccgatgacacggccttatattactgtggaaagcaattgggggcccataaaggggctgactactggggccaggggaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9187 JY8QFUQ01DF0O2 productive Homsap IGHV3-7*01 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDPYKPGSGNPGFDYW in-frame - gcctctggattcacctttagtgactatttgatgacttgggtccgccaggctccaggaaagggactggagtgggtggccaacataaaagaagatggacttgctacattctatgtggactctgtgagggaccgattcaccatctccagagacaacgccaagaactcactttatttgcaaatgaattacctgagagtcgaggacacggctgtttattattgtgcgagggatccctataaacctggttcgggcaatccgggctttgactactggggccagggagcgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9188 JY8QFUQ01DC2T3 No results +9189 JY8QFUQ01B8WF3 productive Homsap IGHV3-72*01 F 975 93.27 208/223 nt Homsap IGHJ6*02 F (see comment) 211 82.26 51/62 nt Homsap IGHD4-11*01 ORF 1 8 10 13 8.10.13 [1.17.38.11] CVRGLQSNYYGMDVR in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtagtagagacaaaattaacagttacagtacagaatatgccgcgtctgcgaagggcagattcaccatctcaagagatgaatcaaagaatttactgtatctgcaaatgaacagcctgagaagcgaggacacggccgtatattactgtgttagaggcctacagagtaattactacggtatggacgtcaggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9190 JY8QFUQ01BB8SR No results +9191 JY8QFUQ01A6D5Q No results +9192 JY8QFUQ01DJVB1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9193 JY8QFUQ01C6DVK unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 849 88.79 190/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD6-25*01 F 3 8 7 X 8.7.X [1.17.38.11] CTRELRMAAARDGVDI## out-of-frame + ctctgggttcgccgtcagtagcaagttcatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatcctgatgggactacacactatggagactccgtgaggggccgattcaccacctccagagacaattctaagaacatcttggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggatggctgcggcgcgtgatggtgttgacatctggggcccaaggcacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9194 JY8QFUQ01B3WVQ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 257 61.96 101/163 nt 61.35 100/163 nt 8 10 X 8.10.X [1.16.20.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (10 AA in JY8QFUQ01B3WVQ ; 8 AA in Homsap_IGHV3-7*01), and low V-REGION identity (61,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcactttcactaacgcctggatgagctgggtccgccaggctccagggaagggctggagtggattggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9195 JY8QFUQ01AATOF No results +9196 JY8QFUQ01ALFG8 productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9197 JY8QFUQ01DLF4V productive (see comment) Homsap IGHV3-7*01 F 747 95.71 156/163 nt 95.09 155/163 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 7 1 11 7.1.11 [X.17.28.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 49 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) gattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9198 JY8QFUQ01CYI6J productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 783 84.79 184/217 nt 84.33 183/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.37.11] CAKDTITMGGDVAPLFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 169 in the user submitted sequence), (cause frameshift) ctctgggattcacctttagtaactatgacatgggctgggtccgccaggctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9199 JY8QFUQ01AHR1C productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtGactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9200 JY8QFUQ01CQ6LV productive (see comment) Homsap IGHV4-61*02 F (see comment) 668 78.28 173/221 nt 77.83 172/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHGLSIGGARELDFW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (78,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 31 of V-REGION: 'C' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); tctctggtggcgccatcaCtgatttttggttccttctggcactggatccgccagcccgccgggggcggactggaatggctcggacgtgtttattataatggggacaccaacctcaatccttccctcaggagtcgactttccatgtcaggagacacgtccaacaaccacttctacctgaggttgaggtctgtgaccgccgaagacacggccacttattattgtgcgagagagcatggtctttcgattggcggagcgagagaacttgacttctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +9201 JY8QFUQ01BRKHB No results +9202 JY8QFUQ01AXACT unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 83 51.54 67/130 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcatcttcagtgactactacatgacctggatccgccaggctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9203 JY8QFUQ01BGFH0 productive Homsap IGHV1-8*01 F 840 88.32 189/214 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD3-16*01 F 1 8 8 18 8.8.18 [0.17.38.11] CARGLTMGENYHSYYGMDAW in-frame + tggatacacattcacccttcatgatatcaactgggtgcgacaggcccctggacaaggacctgagtggatgggatggatgaacccaaacaacaattacagaggttatgcacagaagttccagggccgagtcaccatgaccagggacaccgccacagccacagcctatctggagctgagcagcctgagatcagatgacacggccgtgtattactgtgcgaggggcctaaccatgggggagaattaccactcctactacggtatggacgcctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +9204 JY8QFUQ01AUWMR No results +9205 JY8QFUQ01CYGM0 No results +9206 JY8QFUQ01CZNK7 No results +9207 JY8QFUQ01AE027 No results +9208 JY8QFUQ01B8MBE unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 489 82.98 117/141 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (82,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag +9209 JY8QFUQ01AQ0R8 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttagtagttctggcatgtattgggcccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatgccacaaattacgcagactccgtgaagggccggttcaccatctccagagacaactccatgaacacactgtatctgcaaatgaacagcctgggaaccgatgacacggccttatattactgtggaaagcaattgggggcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga +9210 JY8QFUQ01CPUEG productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9211 JY8QFUQ01AD79A productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 849 87.0 194/223 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD4-23*01 ORF 3 8 10 14 8.10.14 [1.17.38.11] CSRRSTLVTGYVFDKW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggaatcaactttcgtgatcatgccatgagctggttccgccaggttccagggaaggggctggagtgggtaggtttcattagaagttctcaatacggtggagatacagaatacgccgcgtctgtggaaggcagattcaccatctcaagagacgattccaaaagcatcgcctatttggatatgaatagcctgaaaatcgacgacacagccctatattactgttcccggaggtcgacgttggtgactggatacgtctttgacaagtggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9212 JY8QFUQ01AZ1E2 No results +9213 JY8QFUQ01BDD3C No results +9214 JY8QFUQ01BHPNF No results +9215 JY8QFUQ01DWJNN productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDQRGYSYEMDYW in-frame - ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcagcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9216 JY8QFUQ01CK1VY productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 848 87.33 193/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 12 10.7.12 [1.17.38.11] CARGGGWTPYFDSW in-frame + tctctggtggctccgtcagcagtggtaattactactggaactggatccgccaacccccagggaagggactggagtggattggatatatctactatgctggggccaccaacgtcgccccctccctcaagaaccgagtcaccataacgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccgtatattactgtgcgaggggcggtggctggaccccctactttgactcctggggccagggaaatctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccccctaagatcgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9217 JY8QFUQ01COZRA productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 806 85.78 187/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9218 JY8QFUQ01BOOMA No results +9219 JY8QFUQ01CXLBY productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 839 86.88 192/221 nt 85.52 189/221 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD4-23*01 ORF 3 8 10 14 8.10.14 [1.16.38.11] CSRRSTLVTGYVFDKW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 38 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 53 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 76 in the user submitted sequence), (cause frameshift) cctctggaatcaactttcgtgatcatgccatgagctgttccgccaggttccaggaaggggctggagtgggtaggttcattagaagttctcaatacggtggagatacagaatacgccgcgtctgtggaaggcagattcaccatctcaagagacgattccaaaagcatcgcctatttggatatgaatagcctgaaaatcgacgacacagccctatattactgttcccggaggtcgacgttggtgactggatacgtctttgacaagtggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9220 JY8QFUQ01ARH7H productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVKGAGTTVNWFDIW in-frame - cctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9221 JY8QFUQ01DK8VO No results +9222 JY8QFUQ01C1RLY No results +9223 JY8QFUQ01B1K6G productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARPGVGASSFIDFW in-frame + ttctggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +9224 JY8QFUQ01CKQZV productive Homsap IGHV3-9*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9225 JY8QFUQ01BPLD8 productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.18 194/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 12 10.7.12 [1.17.37.11] C#RDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift)in CDR3-IMGT, from codon 105 of V-REGION: 1 nucleotides (from position 221 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9226 JY8QFUQ01AWPQF No results +9227 JY8QFUQ01DGYBA productive Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*02 F or Homsap IGHV3-33*03 F (see comment) 375 79.34 96/121 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 X 2 17 X.2.17 [X.X.38.11] CAKDTITMGGDVAPLFDYW in-frame + Low V-REGION identity (79,34% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +9228 JY8QFUQ01B5OFT unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 123 68.42 39/57 nt 8 X X 8.X.X [1.9.X.X] null + No rearrangement found ctctggattcacctttagtaaccattggatgaactgggtccagggcttcttccccca +9229 JY8QFUQ01AKHML No results +9230 JY8QFUQ01BHHX3 productive (see comment) Homsap IGHV3-48*02 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [2.17.38.11] CVTERGGGLLRYLDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); ggctctggattcatgttcggtagttatagtctgaattgggtccgccaggctccagggaaggGggctggagtggatttcatatattagtagcagtagtcaaacgatttactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgcgagacgacgacacggccatttactactgtgtgacagagaggggcgggggcctattacgatatttggacttatggggcctgggaactcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9231 JY8QFUQ01A0GUN No results +9232 JY8QFUQ01CGAJV No results +9233 JY8QFUQ01A0ECJ productive (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 276 81.18 69/85 nt 80.0 68/85 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); ctctggattcagagacaatgccaggaactctctctacttgcAaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt +9234 JY8QFUQ01DSARW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca +9235 JY8QFUQ01A9YQH productive (see comment) Homsap IGHV3-7*03 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKEQEPHGHYVGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); tcccggattcacttttggtgactattggatgagctgggtccgccaggttccagggaAagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagctgaggacacggccgtgtattcctgtgcgaaagaacaagaaccacatgggcattatgttggaactgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt +9236 JY8QFUQ01DCC26 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame + gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9237 JY8QFUQ01COZCP No results +9238 JY8QFUQ01CMV5N productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtagtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9239 JY8QFUQ01BK4M5 productive Homsap IGHV3-33*03 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARSDLSMVRDLDYW in-frame + gtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatgatttggtatgatggaagccttacatattatgaagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgctgtttctgcaaatgaatagcctgagagtcgaggacacggctctgtattactgtgcgagatccgacctctctatggttagagatcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9240 JY8QFUQ01CV4X4 productive Homsap IGHV4-4*07 F 1061 99.53 214/215 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD4-11*01 ORF 2 8 7 13 8.7.13 [1.17.38.11] CARDFSNRGWYFDLW in-frame - tctctggtggctccatcagtagtttctactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9241 JY8QFUQ01AA0O7 productive (see comment) Homsap IGHV4-39*02 F 852 87.73 193/220 nt 87.27 192/220 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 10 7 17 10.7.17 [1.17.38.11] CARQMGYSGSGLSVWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 62 to 63 in the user submitted sequence), (cause frameshift); ctctggaggctccatcaacactaatcgttactactgggtctggtttcgccagccccccgggGAagggggctggagtggattgggactatttattatactgggatcaccaactacaatccattcttcaagagtcgagtcaccatgtccgtagacacgtccagccaccacttctccctgaggttgagctctgtgaccgccgcagacacggctgtctactactgtgcgagacaaatgggatactctggttcggggctcagtgtgtggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +9242 JY8QFUQ01AGOHV unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 917 90.18 202/224 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD3-22*01 F 3 8 10 X 8.10.X [1.17.38.11] CATDRPYYKNRCWPTLVLLRYGRFG# out-of-frame + tctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagagaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaatcgctgctggccgactctggtattactacggtatggacgttttgggggcccaaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9243 JY8QFUQ01CR4KY productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctgggtggctccatcagtagttactactggagctggatccggcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9244 JY8QFUQ01C8XI8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cttctggattcacctttggtgattatgctatgagctgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9245 JY8QFUQ01CCN84 productive (see comment) Homsap IGHV4-55*03 P (see comment) 739 82.11 179/218 nt 81.19 177/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 9 7 15 9.7.15 [2.17.38.11] CARDQSVYTAGSYFDSW in-frame - Potentially, because of detected insertion/deletion however the closest V is a pseudogene Low V-REGION identity (82,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 173 to 173 in the user submitted sequence), (cause frameshift); gtctctggtgactccatgagtagcgacacgtggtggagctgggtccgccagacgccagagaagggactggaatggattgGgggagatcaatcaaagagggacgacctcctacaacccgtccctcaggagtcgagtcgtcctgtcagtgggcgagtccaaaaatcaattctccCctgaggctgacctctgtgaccgccgcggactcggccatctattattgtgcgagagatcagtctgtctatactgcgggaagttactttgactcctggggccagggaacgctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9246 JY8QFUQ01DFWVC unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [2.17.38.11] CMNELGYCSGG# out-of-frame - in FR3-IMGT at codon 74 of V-REGION: 'GG' (2 nucleotides at position 127 to 128 in the user submitted sequence), (cause frameshift); gcctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaagGGggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9247 JY8QFUQ01CXWID productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9248 JY8QFUQ01BDFG6 unproductive (see comment) Homsap IGHV4-61*02 F 809 86.51 186/215 nt 85.58 184/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD3-10*01 F 1 8 7 17 8.7.17 [1.17.38.11] CARDPPFGELGWGRF*CFG in-frame + stop codons in CDR1-IMGT at codon 37 of V-REGION: 'GGAAAAC' (7 nucleotides at position 24 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaggcgtGGAAAACtattactggagttggcttcggcagcccgccgggaagggattggagtggaTttgggagtttgtatagaggtgggagcaacagctacaatccgtccctcaagagtcgagtcggcatatcagcggacacgtccaggaaccgattctccctgacggtgacttctgtgaccgccgcagacacggccgtgtattactgtgcgagagaccccccatttggggaattgggatggggcaggttttgatgttttgggggccaaggggcaacggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9249 JY8QFUQ01C3Y4I No results +9250 JY8QFUQ01AIN7Q productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CARAYSGPGPYYFDYW in-frame + ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +9251 JY8QFUQ01ADIL3 No results +9252 JY8QFUQ01CE93I unknown (see comment) Homsap IGHV2-5*03 F 177 54.69 105/192 nt 10 7 X 10.7.X [9.17.26.X] null - No rearrangement found gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9253 JY8QFUQ01CB3GX No results +9254 JY8QFUQ01DF6EI No results +9255 JY8QFUQ01AFHD7 No results +9256 JY8QFUQ01A03VN No results +9257 JY8QFUQ01BNODT productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame - ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctgaagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9258 JY8QFUQ01A1VKQ unproductive Homsap IGHV4-61*02 F 978 94.09 207/220 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD1-1*01 F 1 10 7 X 10.7.X [1.17.38.11] CARVRARSNSHPGHSWFD#PW out-of-frame + ctctggtggctccatcagcagcagtagttactactcgacctggctccggcagcccgccggaaagggaccggagtggattgggcatatctatagtagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcggacacggccgtgtattactgtgcgagagtgagggcgcgcagtaatagtcaccccggccacagctggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggcaactca +9259 JY8QFUQ01CLZ8J productive (see comment) Homsap IGHV4-61*02 F 970 93.24 207/222 nt 92.79 206/222 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [2.16.38.11] CARGKWGDKPPFYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) tgtctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaaggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9260 JY8QFUQ01BM8FO productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9261 JY8QFUQ01BNLGB No results +9262 JY8QFUQ01DKBP6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9263 JY8QFUQ01CZ986 No results +9264 JY8QFUQ01AB54F unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 123 68.42 39/57 nt 8 X X 8.X.X [1.9.X.X] null - No rearrangement found ctccggattcacctttagtagttactggatgcactgggtccagggcttcttccccca +9265 JY8QFUQ01DNPWY unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 112 53.73 72/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9266 JY8QFUQ01AJZW6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccagggaaggggctggagtgggtctcaactattcgtgcccgtggtgataggacacactacgcggactccgtgaagggccgcttcaccatctctagagacaattcaaaggacaccctgtatttgcaaatgtacagcctgcgagtcgaggacacggccgtctattactgtgcgaacgaagtcgggtactgtagtagtggggggggaccaggggaccctggtcaccggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +9267 JY8QFUQ01BXREE productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 10 7 25 10.7.25 [1.17.38.11] CAREYPSDRDSSDSSGYLPTSGPLDYW in-frame + tctctggtggctccatcagcagaggtaattactactggacgtggatccggcagcccgccgggacgggactggagtggattgggcgtatctatcccagtgggagaaccaactacagcccctccctcaagagtcgcgtcaccatatcagcagacacgtccaagaaccagttctccctgaagttgacctctgtgaccgccgcagacacggccttgtattactgtgcgagagagtacccctcggacagagattcctctgatagtagtggttatcttcccacctccgggccccttgactactggggcctgggaatccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9268 JY8QFUQ01B5HQ5 No results +9269 JY8QFUQ01AKUDL productive Homsap IGHV4-61*02 F 1010 95.48 211/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*02 F 2 10 7 15 10.7.15 [1.17.38.11] CARAGKQDFWSGYSDDW in-frame + tctctggtggctccatcggcagtggtagttattactggagctggatccggcagcccgccgggaagggactggaataccttgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgctgacacggccatttattactgtgcgagagcggggaaacaggatttttggagtggttattctgacgactggggccagggaaccctggtcatagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9270 JY8QFUQ01C00T0 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 922 92.13 199/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 2 9 7 11 9.7.11 [1.17.38.11] CARASTLRYLDRW in-frame + tctggtggctccatcagcagtgataattggtggagttgggtccgccagcccccagggaagggactggaatggattggggaaatatatcatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacaagtccaagagtcaattcttcctggagctgaggtctgtgaccgccgcggacacggccgtatattattgtgcgagagcctccacactacgatatcttgaccgctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccgaaggtcttcccgctgagcctctgcagcacccanccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +9271 JY8QFUQ01BVUQP unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 X 8.7.X [4.17.38.11] CARGGPHFMI (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION tctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggcccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9272 JY8QFUQ01DSA91 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 652 77.78 168/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (77,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttagcgactatggcatgacctgggtccgccaggctccagggagggggttggagtgggtcgcatctattaatgccggtggtagtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9273 JY8QFUQ01DCXV4 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD1-1*01 F 1 8 8 18 8.8.18 [1.17.38.11] CAREPGRGYTPAMNWYFDLW in-frame + ctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgagagagcctgggaggggttatacacctgcaatgaactggtacttcgatctctggggccgcggcaccctggtcactgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9274 JY8QFUQ01DI94G unproductive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-3*01 F 1 8 10 X 8.10.X [1.17.38.11] CITSFGGRSLAY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9275 JY8QFUQ01CMIQ2 productive (see comment) Homsap IGHV1-2*02 F 835 88.26 188/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [0.17.37.11] CAKHPLRSTSGHSYLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 120 in the user submitted sequence), (cause frameshift) tggatacatattcaccgAccttttatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggatccatcaatcccaacagtggtgtcacaacctacgaagagaagtttcgggcagggtcaccatgaccagggacacgtccatcactacagcctacatggaactgacaagccttacatcagacgacacggccgtatattactgtgcgaaacatcctcttcgatcaacaagtggacattcctacttagattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9276 JY8QFUQ01BM71Y productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 900 90.78 197/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + gtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9277 JY8QFUQ01BL2HM No results +9278 JY8QFUQ01CCEOF No results +9279 JY8QFUQ01CPVC8 productive (see comment) Homsap IGHV3-7*01 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-2*01 F 2 8 8 9 8.8.9 [1.17.38.11] CATRSRSPANW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 86 of V-REGION: 'T' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); ctctggattcagttttagtacctattggatgagctgggtccgccaggctccagggaaggggctggaatgggtggccaccataaacgaggatggaagtgacagaacctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaaaaatTtcattgtatctacaaatgaatagcctgagaaccgacgacacggctcgatattactgtgcgacgcgtagtagaagtccggcgaactggggccagggaagcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagccacagcggcccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +9280 JY8QFUQ01DMIN3 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9281 JY8QFUQ01B3C79 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 702 80.65 175/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRVPTQWFPTLPH##FDIW out-of-frame + stop codons Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaagggcctggaatgggtctctgctatcagtggcagcgatgatcgcacatcttatgttgactccgtgaagggccgcttcaccatctccagagacacttccaggaatacactgtttctgcagatgaacagcctgagcgccgaagatacggccacatacttttgtgtgagagtccccactcagtggtttcccacccttccacactcactttgacatctggggccagggaaccgtggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9282 JY8QFUQ01ASIMC productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 144 to 144 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccCagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9283 JY8QFUQ01DC0FL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 775 84.02 184/219 nt 83.56 183/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [2.16.38.11] CAKDAITMGGDVAPLFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) acctctgggattcacctttagtaactatgacatgggctgggtccgccagctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacgccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9284 JY8QFUQ01ACT0R unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag +9285 JY8QFUQ01A30DY unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD3-16*02 F 3 8 7 X 8.7.X [1.17.38.11] CARAPGWMNPFDF## out-of-frame + ctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggccactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccga +9286 JY8QFUQ01B6LVM productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 873 89.4 194/217 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD6-25*01 F 3 8 8 15 8.8.15 [1.17.38.11] CVRGGRGQQREDAFDIW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcatcttcagtagttatagtttgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatatgagtagttcttacatctattatggagactcagtgaggggccgatttaccatctccagagacaacgccgagagctcactgtatctgcagatgagcagcctgagagccgaggacacggctttatattattgtgtgagaggcgggagggggcagcagcgagaagatgcttttgacatttggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9287 JY8QFUQ01CNJXB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9288 JY8QFUQ01B0KN7 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGHW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9289 JY8QFUQ01BPY8F unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-48*03 F or Homsap IGHV3-69-1*02 P 433 85.0 102/120 nt Homsap IGHJ3*02 F 79 62.0 31/50 nt X 2 X X.2.X [X.X.38.11] CVRDLAARPPYYYYGMDV (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION tctggattcaccttcaactcagtgaagggccgattcaccatctccagagacgactccaagaactcactgtttctgcagatgaacagcctcagagccgaggacacggctgtttattattgtgtgagggatttggcggctcgtcccccttattattactacggtatggacgtctgggccaggggccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggcttcttccccc +9290 JY8QFUQ01DOGII productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 703 80.37 176/219 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [2.17.38.11] CARGLGLNAVYAFDVW in-frame - Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) gcctctggattcgcttttggagattatgccatgaactgggtccgccaggccccagggaagggactggagtgggtctcaggtttgagcggtagaggcgtcagcaaatattatgcagactccgtgaggggccggttctccatttccagagacaactccgggagcgaggcagtccttcaaatgagcagcctgagagtcgaggacacggccacttactactgtgcgaggggcctagggcttaatgctgtctacgcatttgacgtctggggacaggggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9291 JY8QFUQ01BW0XF unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgaaccggtgacggtgtcgtggaactcag +9292 JY8QFUQ01AIAIG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggcgccctgaccagcggcgtgcacac +9293 JY8QFUQ01DTRO5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-7*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKVFQVPGEHHFYYFGMNVW in-frame - cctctggattcatgtttaggaactatgccatgagttgggtccgccaggctccagggagggggctggagtgggtctcaactattagcaataatggaagccacacatactacgcagactccgtcaagggccggttcaccatctccagagacaattccaagaacacggtgtatatgcagatgaacaggctgagagtcgaggagacggccctgtactactgtgcgaaagtcttccaggtgcctggcgagcaccacttctactacttcggaatgaatgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccagga +9294 JY8QFUQ01BULWY productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagcactacttccccgaaccggtgacggtgtcgtggaactcag +9295 JY8QFUQ01BKNFK productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 900 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggcgtggagtgggtcatctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +9296 JY8QFUQ01CDABH productive Homsap IGHV3-48*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTRQTGNYYYFGVDVW in-frame + ctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9297 JY8QFUQ01CJKSZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [2.17.38.11] CARDILGATRFDYW in-frame - gcctctggattcaccttcagcagctatgccatgagctgggtccgccaggctccagggaagggcctggagtgggtctcagctattagtggtattggtgggagtacattctacgcagactccgtgaagggccggttcaccatcaccagagacaattccaacaacacgctgtttctgcaaatgaatagcctgagagccgaggacacggccatatattactgtgcgagagatattctgggagctactcggtttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9298 JY8QFUQ01AHEUW unproductive Homsap IGHV3-7*01 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSGFLLDGLL# out-of-frame - in FR3-IMGT at codon 72 of V-REGION: 'T' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); gctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaTggggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtgggtttttactcgacgggctactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9299 JY8QFUQ01DCEET productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame - tctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9300 JY8QFUQ01B0TW5 productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9301 JY8QFUQ01CL6RH productive Homsap IGHV3-72*01 F 1083 98.65 220/223 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-15*01 F 1 8 10 8 8.10.8 [1.17.38.11] CLRPPRYDPW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9302 JY8QFUQ01CO333 No results +9303 JY8QFUQ01B95LP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9304 JY8QFUQ01AGV8A productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F (see comment) 765 83.87 182/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame - Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gctgggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9305 JY8QFUQ01C465V productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.37.11] CAKDASRYYYNSYCDNW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 213 in the user submitted sequence), (cause frameshift) ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcaatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttattttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9306 JY8QFUQ01DO8CH unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 665 90.62 145/160 nt 90.0 144/160 nt 8 8 X 8.8.X [1.17.19.X] null + No rearrangement found in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaac +9307 JY8QFUQ01B8NC5 No results +9308 JY8QFUQ01C1FIH productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9309 JY8QFUQ01DWOEW unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFDPL# out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgaccccctggggccaggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9310 JY8QFUQ01BCYMS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDFFIGGYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct +9311 JY8QFUQ01B5XDW productive Homsap IGHV3-30*01 F 945 93.09 202/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F (see comment) 114 70.83 34/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [1.17.38.11] CVKNDLSWGTIEHYFDYW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactgggggccagggaaccctggtcacgtctccctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9312 JY8QFUQ01AV4FN No results +9313 JY8QFUQ01AU5BH No results +9314 JY8QFUQ01A3C8Q productive (see comment) Homsap IGHV3-74*03 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [0.17.38.11] CAKVDSDGWHGTIDRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtaAgttactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggatagcgatggctggcacggaacaatagaccgctggggccagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9315 JY8QFUQ01CEK5G unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 814 97.65 166/170 nt 8 7 X 8.7.X [1.17.23.X] null + No rearrangement found ctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttc +9316 JY8QFUQ01BOXSC productive (see comment) Homsap IGHV4-61*02 F 875 88.69 196/221 nt 88.24 195/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); tctctggtggccCccatcagcagcagcacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatcccgacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttccccc +9317 JY8QFUQ01CE1W3 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 925 90.99 202/222 nt 90.54 201/222 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-11*01 ORF 2 8 10 22 8.10.22 [1.17.38.11] CATDRPYYKNAAGRLWYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); tctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgAaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaacgctgctggccgactctggtattactacggtatggacgtttggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9318 JY8QFUQ01BSL07 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - tctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9319 JY8QFUQ01A721G No results +9320 JY8QFUQ01DFNKY productive Homsap IGHV3-72*01 F 1088 98.66 221/224 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-15*01 F 1 8 10 8 8.10.8 [1.17.38.11] CLRPPRYDPW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9321 JY8QFUQ01DGB8B No results +9322 JY8QFUQ01DIZY8 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDLNGGTT# out-of-frame + ctctggattcaccttcactacctcctggatgcactgggtccgccaagctccagggaaggggctaatgtgggtcgcacgtattaataaggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgagagatcttaacggggggactactgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9323 JY8QFUQ01AUXRB No results +9324 JY8QFUQ01BSDG9 No results +9325 JY8QFUQ01AU79L productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 2 9 7 11 9.7.11 [2.17.38.11] CARASTLRYLDRW in-frame - gtctctggtggctccatcagcagtgataattggtggagttgggtccgccagcccccagggaagggactggaatggattggggaaatatatcatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacaagtccaagagtcaattcttcctggagctgaggtctgtgaccgccgcggacacggccgtatattattgtgcgagagcctccacactacgatatcttgaccgctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +9326 JY8QFUQ01BWHRN productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 925 90.99 202/222 nt 90.54 201/222 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [1.16.38.11] CTTAPSETYATEYFAMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctgaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9327 JY8QFUQ01CD99S productive Homsap IGHV3-7*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame - ctctggtttcacatttagtacgtactggatgagttgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9328 JY8QFUQ01B45SQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 651 99.25 132/133 nt 98.5 131/133 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*03 F 3 8 X 18 8.X.18 [1.11.24.11] CAKFMGVVVVPAAHNWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 50 of V-REGION: 84 nucleotides (from position 62 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaagggagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9329 JY8QFUQ01CN4ZQ unproductive Homsap IGHV3-66*02 F 908 91.63 197/215 nt 90.7 195/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [2.16.38.11] CAKLADTGEWSNRIFI#W out-of-frame - in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) agcctctggattcaccgtcagtagcagcttcatgacttgggtccgccagctccaggaaaggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatctttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9330 JY8QFUQ01CWIYB unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRVVLMVHAMS#DFW out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); tctggattcaccttcCgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcgggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9331 JY8QFUQ01B60M1 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatnggtcttcccccctggcaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9332 JY8QFUQ01DMKKA productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9333 JY8QFUQ01BNTGV productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9334 JY8QFUQ01C11GP productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1016 97.21 209/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARGGGYYFVAIDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaagtgggagaaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9335 JY8QFUQ01CSP5B No results +9336 JY8QFUQ01CQSBL productive (see comment) Homsap IGHV4-61*02 F 875 90.57 192/212 nt 89.62 190/212 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 7 13 8.7.13 [0.17.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'CTGGTT' (6 nucleotides at position 19 to 24 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); ccggtggctccatcagtaCTGGTTattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagagggggAcagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9337 JY8QFUQ01DQHIB productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt 88.48 192/217 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-26*01 F 3 8 8 21 8.8.21 [1.17.38.11] CVKDLGSYGSPWRAYYYYGMDAW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); ctctggattcGaccctcaacagcCaatggcatgcactgggtccgccagactccagacaaggggctggagtgggtggcagtgatttcatatgatggaaatgataaatactatggagatgcagtgacgggccgattcaccatctccagagacacttccaagaacacagtatatctggagatgtacagcctgagacctgaggacacggctgtgtattactgtgtgaaagatcttgggagttacggtagtccttggcgcgcctactattactacggcatggacgcctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +9338 JY8QFUQ01DCUZM No results +9339 JY8QFUQ01CW3H6 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ4*03 F (see comment) 26 62.5 10/16 nt 8 8 X 8.8.X [1.17.38.0] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataatttacggtgactantgggggacccaggggaaacccccgttgggctcaccgtctcctcagcatcccctgaccagcccctaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaatg +9340 JY8QFUQ01AFE6A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9341 JY8QFUQ01CCLHR productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctgcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc +9342 JY8QFUQ01DG5UT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 738 82.49 179/217 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +9343 JY8QFUQ01BGA3A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca +9344 JY8QFUQ01AJ082 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'C' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccCaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9345 JY8QFUQ01DR0I6 productive (see comment) Homsap IGHV2-5*02 F 1111 95.47 232/243 nt 95.06 231/243 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 10 7 14 10.7.14 [9.17.37.11] CAHIRAELSTSCHAFW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 182 in the user submitted sequence), (cause frameshift) gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccaggaaaggccctggagtggcttgcacttgtttattgggatgatgataagcgctacagctcatctctgaagagcagactcaccatcaccaaggacacctccaaaaccaggtggtccttacaatgactaacatggaccctatggacacagccacatattactgtgcacacattagggcggaacttagtaccagctgccatgccttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +9346 JY8QFUQ01BOT1H productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 176 to 176 in the user submitted sequence), (cause frameshift); gtctggattcaactcaatagcttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaAatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9347 JY8QFUQ01DTDAG productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKEQEPHGHYVGTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); gtctggattcGaccttcagtagctacggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggccgtgtattcctgtgcgaaagaacaagaaccacatgggcattatgttggaactgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9348 JY8QFUQ01ANSN0 No results +9349 JY8QFUQ01AK94Y unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 46 90.91 10/11 nt 2 X X 2.X.X [1.X.X.X] null + No rearrangement found ctctggattta +9350 JY8QFUQ01BIIIJ productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 662 77.98 170/218 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIVREGLDHW in-frame + Low V-REGION identity (77,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tgtctggtggctccatcgccacttatcattggtggaattgggtccgccagacccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccggaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +9351 JY8QFUQ01DD9VI unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 911 90.5 200/221 nt 90.05 199/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-18*01 F 3 10 7 X 10.7.X [1.17.38.11] CARHSRLVRYF#EFW out-of-frame + in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactggggcCtggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttggaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtctcgcctgcctggtccagggcttcttcccccag +9352 JY8QFUQ01CIG6T productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.37.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 193 in the user submitted sequence), (cause frameshift) agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgaggtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9353 JY8QFUQ01A7QC0 productive (see comment) Homsap IGHV3-33*05 F (see comment) 752 83.03 181/218 nt 82.11 179/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.16.38.11] CVKGRGYNDYGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaagggctggagtgggtggcgaccatttcatatgatAttaatgaaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9354 JY8QFUQ01DN38T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame + ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcatcgcctgccctggtccagggcttcttcccccgag +9355 JY8QFUQ01AFMIM productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 960 93.18 205/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaatacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9356 JY8QFUQ01BZ8RH productive (see comment) Homsap IGHV3-7*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgCcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9357 JY8QFUQ01A75AZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9358 JY8QFUQ01ANOAD No results +9359 JY8QFUQ01B5JBG No results +9360 JY8QFUQ01AVOVU productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1008 98.56 205/208 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-17*01 F 2 6 8 16 6.8.16 [X.17.38.11] CARQLDYGDYSRHGLDVW in-frame + caactttaccggctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccgtgtattactgtgcgagacaattagactacggtgactactctaggcacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9361 JY8QFUQ01AQD2V productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKDRITIFSYNWFDPW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9362 JY8QFUQ01C8R7N productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 935 91.07 204/224 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [1.17.38.11] CTTAPSETYATEYFAMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9363 JY8QFUQ01B47VP No results +9364 JY8QFUQ01DJ7FP No results +9365 JY8QFUQ01BLGB2 productive Homsap IGHV1-8*01 F 1038 98.6 211/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFDYW in-frame + tggatacaccttcaccaattatgatatcaactgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaacagtggtaacacaccctatgcacagaagttccagggcagagtcaccatgaccaggaacacctccataagcacagcctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgcgaggggacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +9366 JY8QFUQ01DRGC4 No results +9367 JY8QFUQ01BJ9SU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaactcag +9368 JY8QFUQ01AXXHP productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1056 99.53 213/214 nt Homsap IGHJ6*02 F 310 100.0 62/62 nt Homsap IGHD5-18*01 F 3 8 8 17 8.8.17 [0.17.38.11] CARPRGYSNYYYYYGMDVW in-frame + tggatacagctttaccagctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggagatcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgaggccccgtggatacagcaattactactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagggagtgcatccgccccaaccc +9369 JY8QFUQ01B1U6L productive (see comment) Homsap IGHV3-74*03 F 900 90.78 197/217 nt 89.86 195/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-20*01 F 3 8 8 14 8.8.14 [1.17.38.11] CVREKSSNWNRWFDTW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'CA' (2 nucleotides at position 73 to 74 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagccactggatgcactggGgtccgccaaggtataggggaggggctgggtgtggCAttgcacgtattaacagtgatggcagtagtacagcttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaagacgctttatctgcaaatgaacagtctgagagtcgaggacacggctgtctattactgtgtaagagagaaaagtagtaattggaaccgctggttcgacacctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacatggtcgtcgcatgcctggtccagggcttcttccccca +9370 JY8QFUQ01DWK39 No results +9371 JY8QFUQ01C5EGC No results +9372 JY8QFUQ01CG58I productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9373 JY8QFUQ01BTW6P No results +9374 JY8QFUQ01DAX5H unproductive Homsap IGHV3-48*02 F 891 90.32 196/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARGQNGYKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9375 JY8QFUQ01A06W8 No results +9376 JY8QFUQ01AO6XS No results +9377 JY8QFUQ01A95GG No results +9378 JY8QFUQ01BX599 No results +9379 JY8QFUQ01C0RN1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +9380 JY8QFUQ01A44VT unproductive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAGGRGWLIDY# out-of-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactgggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9381 JY8QFUQ01C07DV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKKSIIIRGLI#YNFDYW out-of-frame + ctctggatttacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaagcattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtcc +9382 JY8QFUQ01BG9FB No results +9383 JY8QFUQ01DXF3F No results +9384 JY8QFUQ01CIUPL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9385 JY8QFUQ01A5NL9 productive (see comment) Homsap IGHV1-3*01 F 840 88.32 189/214 nt 87.38 187/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); tggatacagcttcactaatcacattatccattgggtgcgccaGggcccccggacaagggcttgagtgggtggGggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccactgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9386 JY8QFUQ01BCHGI unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 80 51.13 68/133 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons tctggattcacctttaacctctatgtcatgcactggttccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9387 JY8QFUQ01BHZ2A No results +9388 JY8QFUQ01BHT2Y productive Homsap IGHV3-53*04 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 3 8 7 12 8.7.12 [1.17.38.11] CARQTAPFGNFDLW in-frame - tctcggggttcaccgtccaaaacagcttcatgagttgggtccgccaggctccagggaagggcctagagtgggtctcagttgtttatagtggtggatccacatactacgcagactccgtgaagggccgtttcaccatcgccagacacagtcgcaacaacattctgtatcttcaaatgaacagcctgagacctgaggacacggctgtttatttctgtgcgagacagactgccccctttgggaactttgacttatggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9389 JY8QFUQ01BJH31 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcatctttgatgattttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccaaagtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9390 JY8QFUQ01B90A3 No results +9391 JY8QFUQ01DWCOM No results +9392 JY8QFUQ01B4PEO No results +9393 JY8QFUQ01BXPNK No results +9394 JY8QFUQ01B2QGE No results +9395 JY8QFUQ01B22NV productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9396 JY8QFUQ01AGQWQ productive (see comment) Homsap IGHV3-69-1*02 P 920 92.92 197/212 nt 92.45 196/212 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-20*01 F 3 8 7 10 8.7.10 [1.16.38.11] CARDDKWAFDYW in-frame + Potentially, because of detected insertion/deletion however the closest V is a pseudogene in FR2-IMGT, from codon 55 of V-REGION: 3 nucleotides (from position 78 in the user submitted sequence), (do not cause frameshift) tctctggattcaccttcagtgactacagcatgaactgggtccgccaggctccagggcaggggctggagtgggtctcatatagtcgcggaagaaccacatactacgcagactctgtgcagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgacagccgaggacacggctgtttattactgtgcgagagatgataagtgggcatttgactactggggccagggaaccctggtcgtcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9397 JY8QFUQ01BX1DY productive (see comment) Homsap IGHV3-30*04 F, or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*03 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVRGSSGRFDSW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagaaaatatgctatgcactgggtccgccaggctccaggcaaggggctggaatgggtggcgattatatcctatgatggaagaagtccatactacgcagactccgtgaggggccgattcaccatctccagagacaattccaggagtactctggatctgcagatgaacagcctgagacctgaggacacggctgtatattcctgtgtgagaggaagcagtggccgctttgactcctggggcccgggaacgctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9398 JY8QFUQ01C4ODX unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 778 92.74 166/179 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattga +9399 JY8QFUQ01AFKGR unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 82 90.0 18/20 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found tctggattcactgtcaataa +9400 JY8QFUQ01ALMB4 No results +9401 JY8QFUQ01BHE7H No results +9402 JY8QFUQ01A1158 productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc +9403 JY8QFUQ01CTINS No results +9404 JY8QFUQ01AF7NW unknown (see comment) Homsap IGHV3-71*01 P, or Homsap IGHV3-71*02 P 131 52.49 95/181 nt 8 6 X 8.6.X [1.17.28.X] null - No rearrangement found ctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtcctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccgaccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9405 JY8QFUQ01CDSV8 No results +9406 JY8QFUQ01B4WKB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1005 95.45 210/220 nt 95.0 209/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); ggcctctggattcagcttGcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9407 JY8QFUQ01BCE04 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9408 JY8QFUQ01BEO43 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9409 JY8QFUQ01CE1WF No results +9410 JY8QFUQ01BDZT5 No results +9411 JY8QFUQ01A3SEN No results +9412 JY8QFUQ01AARD4 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 1003 96.3 208/216 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD6-6*01 F 1 8 7 17 8.7.17 [2.17.38.11] CAKGDSSSSKYYYYGMDVW in-frame - gcctctgggttcagcgtcagtatcaactacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtagcacacactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccttgtatcttcaaatgaacaacctgagagccgacgacacggccgtgtattactgtgcgaaaggtgatagcagctcgtccaaatactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9413 JY8QFUQ01C3Q4U productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1062 96.9 219/226 nt 96.02 217/226 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 132 to 132 in the user submitted sequence), (cause frameshift); taccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtGccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgGaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +9414 JY8QFUQ01C0IDN unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 127 69.64 39/56 nt 8 X X 8.X.X [1.9.X.X] null - No rearrangement found ctctggattcacctttagtaaccattggatgaactgggtccagggcttcttcccca +9415 JY8QFUQ01BH0LW productive (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 285 82.35 70/85 nt 81.18 69/85 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); ctctggattcagagacaatgccaggaactccctctacttgcAaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9416 JY8QFUQ01AJM01 No results +9417 JY8QFUQ01BABC7 unproductive Homsap IGHV1-3*01 F 872 89.77 193/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [0.17.38.11] CARDGYRSGNG#DYW out-of-frame - tgggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacgggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +9418 JY8QFUQ01C85JY unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt 92.79 206/222 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD5-24*01 ORF 1 8 7 9 8.7.9 [4.16.38.11] CARGAPFS**C in-frame + stop codons in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaagggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9419 JY8QFUQ01DPTPU No results +9420 JY8QFUQ01DUJ85 No results +9421 JY8QFUQ01A208J productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 937 92.24 202/219 nt 90.87 199/219 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDGGSYNRMDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 82 of V-REGION: 'G' (1 nucleotides at position 155 to 155 in the user submitted sequence), (cause frameshift); gcgtctggattcaccttcagtagctatgGgcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtGgaaatatattatgaagagtccgtgaaggaccgattcaccgtctccagagacaaGttccaagaacacggtgtatttggaagtgaatagtctgagagtcgacgacacggctgtgtattactgtgcgagagacggtgggagctacaacaggatggacctttggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +9422 JY8QFUQ01CJ7WY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 92.99 199/214 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [1.17.38.11] CAKEGNLGYFDDW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaAaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9423 JY8QFUQ01DBYFF No results +9424 JY8QFUQ01A0X34 unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*02 F or Homsap IGHV3-33*03 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 482 89.92 107/119 nt 89.08 106/119 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD3-3*01 F 3 8 X X 8.X.X [1.14.16.11] CARDFLAPNRFRSV##YYYYGMDVW out-of-frame + stop codons in FR2-IMGT, from codon 53 of V-REGION: 105 nucleotides (from position 72 in the user submitted sequence), (do not cause frameshift) cgtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaggggtctggaatggttggcaatgatatgcctgagagtcgaggacacggctgtctattactgtgcgagggatttcttagccccgaatcgttttcggagtgtttgactactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +9425 JY8QFUQ01CI7ES productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1031 97.25 212/218 nt 96.79 211/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 11 8.8.11 [2.16.38.11] CVVQILGATIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcaatacctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtggtagtacttacataaagtacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtggtccagatcctaggggctacgattgactactggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9426 JY8QFUQ01ANECI unproductive Homsap IGHV3-21*04 F 633 94.37 134/142 nt 93.66 133/142 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 102 66.67 34/51 nt Homsap IGHD6-13*01 F 1 8 X X 8.X.X [1.2.35.11] CARAVSHQVDV## out-of-frame - Other possibilities: Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ2*01 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 41 of V-REGION: 76 nucleotides (from position 38 in the user submitted sequence), (cause frameshift) cctctggattcgacttcagtagatatatcatgaattggactcagtgaagggccgattcaccatctccagagacaacgccaagaactcgctgtttctgcaaatgaacagcctgagagccgatgacacggccgtgtattactgtgcgagagccgtgtcgcatcaggtggacgtctggggccaagggggccacggtcaccgtctcctcagcatccccgatcagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9427 JY8QFUQ01AA90J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - tctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9428 JY8QFUQ01CI8OX unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +9429 JY8QFUQ01BLI3C productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDPSGSGWAFESW in-frame + gtctggattccctttcagtagagatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatggtatggtatgatggaagtaatacacaccatgcagattccgtgaagggccgattcatcatttccagagacaattccaagaataaagtgtatctgcaaatgaacagtctgagagacgaggacacggctgtctattattgtgcgagagatccgagcggcagtggctgggcctttgagtcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9430 JY8QFUQ01BC44E unproductive (see comment) Homsap IGHV4-61*08 F 884 89.14 197/221 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctctggtgcctccatcagcagtagtggtcactactggagttggatccggcagcccccagggaagggactggaattcattggaaaaatctattccaatgggaacgccaactacaacccctccttcaagagtcgagtcaccatttcagtggacacgtccgagaaccagttctccctgagcctgaggtctgtgaccgctgcggacacggccctttattactgtacgagggggggtatacacttatgacagcccgtggggccaggggcattcaggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9431 JY8QFUQ01B0NL2 productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9432 JY8QFUQ01BDPBH unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9433 JY8QFUQ01DOF76 No results +9434 JY8QFUQ01CEVZ4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDPGNYWGYYYDSW# out-of-frame + gtctggattcacctttagtgattatgccttgagctgggtccgccagactcccgggaaggggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgagagatccgggaaattattggggatactattatgactcttgggggcctggggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9435 JY8QFUQ01C32QR unknown (see comment) Homsap IGHV3-64*03 F, or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 184 59.7 80/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggcaacgtggtcgtcgcatgcctggtccagggcttcttcccc +9436 JY8QFUQ01ADBXZ unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.16.38.11] CVRGDYGGAPRTLLRP#YGLDVW out-of-frame + in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccaggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccaggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctctaagagcacctctgggggccacagcggccctgggctgcctgggtcaaagggactactttgccccgaaccggtgacggtgtcgtggaactca +9437 JY8QFUQ01ANLRW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9438 JY8QFUQ01CC1JT productive Homsap IGHV3-64*02 F 953 93.95 202/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVTCGDYSYEYW in-frame - ctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9439 JY8QFUQ01ALGU6 productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9440 JY8QFUQ01BFGBW unknown (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggaacagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9441 JY8QFUQ01AJP8I unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1009 95.89 210/219 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [2.17.38.11] CVRGDYGGAPDITTT#YGLDVW out-of-frame - gcctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9442 JY8QFUQ01DS9GC productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDFW in-frame + cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +9443 JY8QFUQ01BKBNA productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 932 92.2 201/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [2.16.38.11] CATDDSNGWDEVADYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'T' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagctcccattggatgaactgggtccgccagactccagggaagggctggagtgggtggccaacataaaggaagatggaagtgTggaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9444 JY8QFUQ01BHZ4Z productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccatggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagtggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca +9445 JY8QFUQ01CDSCT productive Homsap IGHV3-48*03 F, or Homsap IGHV3-48*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P (see comment) 357 75.38 98/130 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 X 5 13 X.5.13 [X.X.38.11] CATSPSDFDRRWGYW in-frame + Low V-REGION identity (75,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggatttagctttagaaccttttggatgagctggggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9446 JY8QFUQ01BBIKE productive Homsap IGHV3-9*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDRKGSNWYYFENW in-frame - cctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9447 JY8QFUQ01BFIR7 No results +9448 JY8QFUQ01A3ZJ5 productive Homsap IGHV3-33*03 F (see comment) 761 83.49 182/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CARDRQSWGIDSW in-frame + Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cgtctggattcgacttcagtagttatggcttccattgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaattacctacgcagactccgtgaagggccgattcaccatctccagagacaacgccaagaatacactttttcttcaaatgacttccctgagagtcgaagatacggccatttattactgtgcgagagatcgtcagagctgggggattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9449 JY8QFUQ01BSZIQ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcacggtctcctcagcatccccgaccaaccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +9450 JY8QFUQ01AVH1O productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1026 97.24 211/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 11 8.8.11 [1.17.38.11] CVVQILGATIDYW in-frame + ctctggattcaccttcaatacctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtggtagtacttacataaagtacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtggtccagatcctaggggctacgattgactactggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9451 JY8QFUQ01B1YE0 productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 3 8 8 11 8.8.11 [1.17.38.11] CASLARGDGRDYW in-frame + gtctggattctactttaataatttttggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaagtgcgaaagagtatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaaaaactcactgtttctgcaaatggacagcctgagagtcgaggacacggctgtttattactgtgcgagcttggcacggggagacgggagggactactggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +9452 JY8QFUQ01C1A12 productive (see comment) Homsap IGHV3-48*01 F 1004 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 2 8 8 9 8.8.9 [2.16.38.11] CRGDPTQRDYG in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gcctctgggttcaccttcagtagttatagcatgaactgggtccgccaggctccaggaaggggctggagtggctttcattcattactagtagtggtagtaccgtatactacgcagactctgtgaagggccgattcaccatctctagagacaatgtcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgccgcggtgaccctactcaacgtgactacgggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9453 JY8QFUQ01DNK8N productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9454 JY8QFUQ01BBDN7 No results +9455 JY8QFUQ01A6QVX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9456 JY8QFUQ01DML0H unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 884 91.04 193/212 nt 88.21 187/212 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD2-21*01 F 3 8 7 X 8.7.X [2.16.36.11] CVRGGVSGAFRWGLDY# out-of-frame - in CDR2-IMGT at codon 57 of V-REGION: 'TG' (2 nucleotides at position 83 to 84 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 2 nucleotides (from position 83 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 91 of V-REGION: 2 nucleotides (from position 174 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 204 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaagggctggtgtgggtctcacgaatTGatagttctgcgaatctcatcaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctgcaatgacagtctgagagccgacgacacggctgttactactgtgtgagagggggagtcagtggggccttcaggtggggtttggactactgggccagggaaccctggccaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9457 JY8QFUQ01AJUSF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD6-25*01 F 1 8 8 22 8.8.22 [1.17.38.11] CARYQGDTSGYQDVFYAHYGMDVW in-frame - Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacttttaggggctactggatgcactgggtccgtcaggttccaggtaaggcgccggagtggctcgcacgtctgaatactgatggagatagtacaagttatgcggactccgtgaagggccgcttcaccatctccagagacaacgccaggagcacattgttcctgcaaatgagcagtctgagagtcgaagacacggccatttattactgtgcacggtatcagggcgataccagtggctaccaggacgttttctacgcccactacggtatggacgtctggggccaagggacctcggtcaccgtctattcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +9458 JY8QFUQ01BHMYN unproductive (see comment) Homsap IGHV4-4*07 F 868 89.35 193/216 nt 87.5 189/216 nt Homsap IGHJ1*01 F 80 61.54 32/52 nt Homsap IGHD3-16*01 F 3 8 7 10 8.7.10 [2.17.38.11] CARDSGGL*LLG in-frame - stop codons in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'T' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'A' (1 nucleotides at position 208 to 208 in the user submitted sequence), (cause frameshift); gtctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtcCcaaaccagtgggagCcccccactacaacccctTccctcaagagtcgagtcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccActttttttctgtgcgagagactccgggggactttgactactgggggccccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9459 JY8QFUQ01CTUZY productive Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + cctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttcccccag +9460 JY8QFUQ01B5UYP productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); gtttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +9461 JY8QFUQ01BNE4W productive Homsap IGHV4-61*02 F 902 90.05 199/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD2-21*01 F 3 10 7 14 10.7.14 [1.17.38.11] CAREKVVIRPNWFDPW in-frame + tctctggtgactccatcaccagtggtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaatccctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagagaaaaggtagtgatccgtcccaactggttcgacccctggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9462 JY8QFUQ01ARAFR productive (see comment) Homsap IGHV3-48*02 F 869 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 3 8 8 10 8.8.10 [1.17.38.11] CASGGVTEAHYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 100 of V-REGION: 'GG' (2 nucleotides at position 204 to 205 in the user submitted sequence), (cause frameshift); cctctggattcagctccagtgaatataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattggtgttggtactggtggcatatactacgcagactctgtgaggggccgattcaccatctccagggacaatgccgagaactcagtgcatctgcaaatgaacagcctgagagacgacgacacgGGgtgttttattactgcgcgagcggaggggtgacagaggctcactactggggccagggaaccctggtcaccgtctcgtcagcatccccggaccagcccccaagggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9463 JY8QFUQ01BHSSH No results +9464 JY8QFUQ01BT7B7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1090 100.0 219/219 nt 99.09 217/219 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [2.16.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) agcctctggattcaccGtttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9465 JY8QFUQ01CXX81 unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 98 of V-REGION: 'G' (1 nucleotides at position 198 to 198 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgagGgacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9466 JY8QFUQ01DFXSD productive Homsap IGHV4-61*02 F (see comment) 649 77.63 170/219 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARGHSGSTGGARQLDSW in-frame + Low V-REGION identity (77,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggtggccccttcagtagttatttctacctctggcactgggtccggcagcccgccggaaagggactggagtggatcggacacactttcagtaatggggccatcacctacaatgccgctctcaagggtcgagtcgccatgttagtggacgtgtccaagagacagttctccctgaggttggcctctgtgaccgccgcagacacggccatatattattgtgcgaggggacatagcgggtcgactggcggagcgagacaacttgactcctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +9467 JY8QFUQ01ARSP1 productive (see comment) Homsap IGHV3-48*01 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'GGGGGG' (6 nucleotides at position 65 to 70 in the user submitted sequence), (do not cause frameshift); ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctgGGGGGGgagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9468 JY8QFUQ01ADWZ0 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 927 92.17 200/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARVGGTEEFAGMLELDYW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gtctggattcagtttcagtagctttggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatgatctggtatgatggaactaataaatattatgcagactccgtgaagggccgattcaccatctcgagagacaattccaagaacacactgtttctgctcatggacagcctgacagccgacgacacggctgtctattactgtgcgagagtcgggggaaccgaggagttcgctggtatgttggaacttgactactggggccaggggaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +9469 JY8QFUQ01AQH9S No results +9470 JY8QFUQ01BYYS7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F (see comment) 132 75.0 36/48 nt Homsap IGHD6-13*01 F 1 8 8 10 8.8.10 [1.17.38.11] CANEVGYCSSGG in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccagggaaggggctggagtgggtctcaactattcgtgcccgtggtgataggacacactacgcggactccgtgaagggccgcttcaccatctctagagacaattcaaaggacaccctgtatttgcaaatgtacagcctgcgagtcgaggacacggccgtctattactgtgcgaacgaagtcgggtactgtagtagtggggggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9471 JY8QFUQ01AKHTH productive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1001 95.02 210/221 nt 94.57 209/221 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARMPRGETGYGDDNNYFDPW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift); tctctggtgactccatcaacaggggtggttattTtctggagctggatccgccagcacccagggaagggcctggtgtggattgggtacatctattacagggggagcacctactacaacccgtccctcaagagtcgagttaccatatcaatagacacgtctaagaaccagttctccctgaggctgagctctatcactgccgcggacacggccgtgtattactgtgcgaggatgccccgtggagagactggctacggggatgataataattacttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +9472 JY8QFUQ01ARYPI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattaatggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9473 JY8QFUQ01BFE8S productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 3 8 8 14 8.8.14 [2.17.38.11] CARSVSLNRGAYFDCW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 82 of V-REGION: 'T' (1 nucleotides at position 154 to 154 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagcagctatgccctgagctgggtccgccaggctccagggaaggggctcgaatgggtctcagctgttggcggtggcggtagtaacacatactatgcagactccgtgaagGggccggttcaccatctccagagacaaTttccaagaacacactgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatttctgtgcgagatccgttagtctgaatcggggagcttactttgactgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9474 JY8QFUQ01BLXGN No results +9475 JY8QFUQ01BXD9T unproductive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*03 F 69 60.42 29/48 nt Homsap IGHD6-25*01 F 3 8 7 X 8.7.X [1.17.38.11] CARQRGGGDRQWAFEN# out-of-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaaccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactca +9476 JY8QFUQ01CUPTB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); ctccgggattcaccGtttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9477 JY8QFUQ01AKKH7 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 750 83.64 179/214 nt 83.18 178/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9478 JY8QFUQ01C319O productive Homsap IGHV4-4*07 F 808 86.85 185/213 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9479 JY8QFUQ01BF115 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 103 62.9 39/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9480 JY8QFUQ01BG8O8 No results +9481 JY8QFUQ01CUIH8 unproductive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD6-6*01 F 2 8 7 X 8.7.X [1.17.38.11] CARGSSKS#YNWFDPW out-of-frame - ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtccaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9482 JY8QFUQ01A86BJ unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 945 93.09 202/217 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDTGQWKDFDY# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtactaacacgggggggactaacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +9483 JY8QFUQ01B580Q No results +9484 JY8QFUQ01DADF3 productive Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 740 81.82 180/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARVWVAGSRDENFDSW in-frame + Low V-REGION identity (81,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgggtgcttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgccctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9485 JY8QFUQ01CFS8F unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 946 92.27 203/220 nt Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD1-26*01 F 3 10 7 X 10.7.X [1.17.38.11] CARQLEEGREVLQWNDA#FAIW out-of-frame - ctctggtggctccataagtagtagtagacactattgggggtggatccgccagcccccagggaagggactggagtggattggcagtatgtattatagtggggacacctactacaatccgtccctcaagagtcgagtcgccatatccgcagacacgtccaagaaccggttntccctgaagctgagctctctgaccgccgcagacacggctgtgtattactgtgcgaggcagcttgaggaggggcgggaggtactacaatggaatgatgctttttgctatctggggccaggggacagtggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +9486 JY8QFUQ01BNPV4 No results +9487 JY8QFUQ01DPOR8 productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [2.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); agtctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9488 JY8QFUQ01BVEWH unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found agttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +9489 JY8QFUQ01AOTCJ productive Homsap IGHV3-30*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAGDLTGVPYYYDSSGLKYW in-frame + ctctagattcaccttcagtagctataatatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +9490 JY8QFUQ01C9EZR No results +9491 JY8QFUQ01BX9KN No results +9492 JY8QFUQ01B5VDA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 535 92.06 116/126 nt 91.27 115/126 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD1-20*01 F 2 8 X X 8.X.X [1.6.26.11] CANASPRITGTYFYYYGY#DVW out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 45 of V-REGION: 91 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacgggtatggacgtctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9493 JY8QFUQ01DHT6B unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.74 200/218 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CGKPIVGATGREMPVS## out-of-frame + cctctggattcacctttagcaactatgccatgaactgggtccgccaggttccaggggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttcctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9494 JY8QFUQ01A4M2H unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 914 91.28 199/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRVGAPYYDFWSGYQTNWFD#PW out-of-frame + cgtctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgcaagtactacttccatacattatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggcgccatattacgatttctggagtggctatcagactaactggttcgaccccgtggggccagggaactctggtcaccgttacctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9495 JY8QFUQ01BFYZZ unproductive Homsap IGHV3-66*02 F 894 91.12 195/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [2.16.38.11] CAKLADTGEWSNRIFI#W out-of-frame - in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcaatagcagcttcatgacttgggtccgccagctccaggaaaggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatctttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9496 JY8QFUQ01CSDKO productive Homsap IGHV4-39*03 F 919 91.28 199/218 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - tccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9497 JY8QFUQ01BPYWA No results +9498 JY8QFUQ01DHWO6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [2.17.38.11] CARGGLEPVDYW in-frame - ccctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9499 JY8QFUQ01A90FM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [1.17.38.11] CVKDRDFLWGSYRLQLESW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcacctttagtagctatggcatgagttgggtccgccagtctccaaataagggactggagtgggtcgcaggcattagtgcaaatggtggcagtataaattatctggacgccgtgaagggccggtttatcatctctagagacaattccaagaacacgttgtatctgcaaatggacagcctgacagtcgaggacacggccgtttattactgtgtgaaagatcgtgattttctttgggggagctatcgtcttcaacttgaatcttggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9500 JY8QFUQ01DWTCH No results +9501 JY8QFUQ01DQ6K4 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 787 85.19 184/216 nt 84.72 183/216 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD2-2*02 F 1 8 8 19 8.8.19 [1.17.38.11] CARDGSPHSPIYHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); tctggattcagcttcggtagtcatgttatgaactTgggtccgccaggctcccggaaagggcctggagtgggtcgcaacaattggaacaagaagtaagtctatatattacgcagactcagtgaagggccgatgcaccatatccagagagaacgcccataactcaatgtatctgcaactgaacagcctgacagccgaggacacggctgtttattactgtgcgagagacggcagtccacactcgccgatctaccactactattatggtatggacgtctggggccaagggaccacggtcatagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9502 JY8QFUQ01AN4CJ productive Homsap IGHV3-7*01 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAREQSSRGYPLDYW in-frame + tctggattcacctttagtactttttggttgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaggaactcactgtttctgcaaatgaacagcctgagaggcgacgacacggctgtctattactgtgcgagagaacaatcctcgaggggatatccacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9503 JY8QFUQ01ATP88 productive (see comment) Homsap IGHV4-34*10 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaAagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9504 JY8QFUQ01BCHZM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1085 100.0 218/218 nt 99.08 216/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); cctctggattcaccGtttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcGtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9505 JY8QFUQ01CF35R unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 176 58.82 80/136 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9506 JY8QFUQ01BTR4I productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 828 87.1 189/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGFSAWGQDAFDIW in-frame + ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9507 JY8QFUQ01DCF12 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 697 80.56 174/216 nt 80.09 173/216 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [2.17.38.11] CARLDGHFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); atctctgggttcaccatcactcactactccatggcctgggtccgccaggctccggggaaggggctggagtgggtctcattgatttatcccggcgggagcacattccacgcagactccgtgaCgggggcgcctcatcatctccagagacgagtccaagggtgaggtgtatcttcggatgacgagggtgaaaaccgaagacgcggccgtgtattactgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtctctgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9508 JY8QFUQ01C2LWF productive (see comment) Homsap IGHV3-11*01 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9509 JY8QFUQ01CFTTB productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ6*02 F 175 75.81 47/62 nt Homsap IGHD3-16*01 F 1 8 8 14 8.8.14 [1.16.38.11] CARAVGQRGYDGTDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcatgttcagcagttattggatgagctgggtccgccaggatccagggaagggctggagtgggtggccaatataaacgaagaaggaagtgagaaatattatgtggactctgggaagggccgattcaggatctccagagacaacgccaagaattccgtgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgcgagagcagtggggcagcgaggctacgacggtacagacctctggggccaagggaccacggtcatcgtctccacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9510 JY8QFUQ01A948I productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacacagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9511 JY8QFUQ01CDG9O productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 822 85.65 191/223 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARRHYGEGLFDYW in-frame - gtcctttggtggctccatcaccaataataattacttctggggctggatccgccagcccccagggaaggggctggagtggattggggatgtccagtatagtgggagcacctactccagcccgtccctcaagaggcgggtcaccatgtctgtggacgtgtccaaaagtcaggtctccctgagactgagctctgtgaccgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9512 JY8QFUQ01BPT8C productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 951 92.73 204/220 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD3-10*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARRGSYGSGSYYPW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggtggcgccatcagcagtaatagttactactgggactggatccgccagcccccagggaaggggctggagtggattgggagtatgttttatactggggtcaccttctacaacccgtccctcaagagtcgagttaacatttccgtggacacgtccaagagccagttctccctgaggctgagctctgtgaccgccgcagacacggctgtgtatcactgtgcgagacgtggttcctatggttcggggagttattatccctggggccggggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9513 JY8QFUQ01B61T7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9514 JY8QFUQ01B3R8A productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9515 JY8QFUQ01BV9PI unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9516 JY8QFUQ01AQWBS productive (see comment) Homsap IGHV4-39*02 F 978 94.09 207/220 nt 93.64 206/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.16.38.11] CARIVVRQFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtgactccatttccagtactagttattactggggctgggtccgccagccccagggaaggggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaatcctggtcaccgtctcctcacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9517 JY8QFUQ01BJC1Y productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcctcccgctgagcctccgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9518 JY8QFUQ01A2S2M productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaAaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9519 JY8QFUQ01C2LKX productive Homsap IGHV3-9*01 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [1.17.38.11] CVKDIHGKYSYLMDVW in-frame + cctctggaatcaatcttgatgattatggcctgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaaaaggggtagtgtagcctatgcggactctgtgaagggccgattcaccatctccagagactacgccaagaactccctgtatctgcaaatgaatagtctgagagtagaggacacggccttgtattactgtgtgaaagacatccatggcaaatactcctaccttatggacgtctggggccaagggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9520 JY8QFUQ01B4X7N productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9521 JY8QFUQ01AY9SW productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9522 JY8QFUQ01A8MAI productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 924 91.36 201/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 14 10.7.14 [1.17.38.11] CARRALDSSGHYIDIW in-frame + ctctggtggctccatgagcagtggtaattactgctggggctggggccgccagcccccaggaaaggggctggagtggattggaagtatgtgttatggtgggagcacctactacagcttgtcccccaagggtcgagtcaccatatccatagactcgtcgaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagacgcgcattagacagtagtggtcattacattgacatctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +9523 JY8QFUQ01B4P9J productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVSDLAGQKGFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 75 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); caggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccGgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9524 JY8QFUQ01CXODK No results +9525 JY8QFUQ01CE0PZ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9526 JY8QFUQ01CL1NE productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 798 85.0 187/220 nt 84.09 185/220 nt Homsap IGHJ6*02 F (see comment) 188 78.69 48/61 nt Homsap IGHD1-14*01 ORF 2 10 7 12 10.7.12 [1.17.38.11] CTRQGPYLYGFDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'T' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift); ctctggtgtttccgtcagtaacactGattttctattggggTctgggtccgccagtccccagggaagggactggagtggattggcagtgtagattatagtgggagcgcttcctacagccctgccctcaagagtcgagtcatcatatccatagacacgtccaagaaccagttctccatagctctgagttctgtgaccgccgcagacacggctgtctattattgtacgagacagggaccctacctctacggtttcgacgtctggggccaagggaccacggtcaccgcctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +9527 JY8QFUQ01CG0FA productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1115 100.0 224/224 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [2.17.38.11] CARSRTFYGSANYW in-frame - ctgtctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9528 JY8QFUQ01C1PJV productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 591 95.38 124/130 nt 94.62 123/130 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 X 11 8.X.11 [1.3.31.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 38 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagtaaccattggatgaactggggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9529 JY8QFUQ01CY6CU unproductive (see comment) Homsap IGHV3-7*01 F 850 88.43 191/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame - stop codons ctctagatcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9530 JY8QFUQ01BW93K No results +9531 JY8QFUQ01C3NBA No results +9532 JY8QFUQ01AGDKF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARRTITAAGRGDDYR in-frame - ctctgaattcacctttagcagttttgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagcattggtactagtgttgttaacacatggtacgcagactcagtgaagggccggttcgccatttccagagacaattccaagagcacgctgtatttgcaaatgaatagcctgagagtcgaggacacggccgtatattactgtgcgaggaggacaataacagcagctggccgtggggatgactaccggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +9533 JY8QFUQ01CYRUR productive (see comment) Homsap IGHV1-2*02 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); ctggatatactttcaccgaccattatgtttactggatgcgacaggGcccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9534 JY8QFUQ01A7AMF productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1025 97.67 210/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARGGGYYFVAIDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +9535 JY8QFUQ01BOTHE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 805 86.11 186/216 nt 85.65 185/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.37.11] CVKDYGNCGGGRCYSIPLDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 71 of V-REGION: 1 nucleotides (from position 121 in the user submitted sequence), (cause frameshift) ctctggatttacctttagccgctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcattattgatgttaattctttcacatactacgcagactctgttcgggccggttcaccgtgtccagagacgattccaagaacacggtatatctgcaaatgaacagtttgagacccgacgacacggccgtttattattgtgtgaaagattacggtaactgtggtggtggtcgctgctattcgattccccttgactactggggccggggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9536 JY8QFUQ01BZ7N9 No results +9537 JY8QFUQ01A79PR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9538 JY8QFUQ01BLAI9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 979 95.77 204/213 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [X.17.38.11] CAKKYHYGSGSYLYCFDYW in-frame - ggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtggtgatgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactgctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +9539 JY8QFUQ01BAKGF productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 848 87.33 193/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 12 10.7.12 [1.17.38.11] CARGGGWTPYFDSW in-frame - tctctggtggctccgtcagcagtggtaattactactggaactggatccgccaacccccagggaagggactggagtggattggatatatctactatgctggggccaccaacgtcgccccctccctcaagaaccgagtcaccataacgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccgtatattactgtgcgaggggcggtggctggaccccctactttgactcctggggccagggaaatctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9540 JY8QFUQ01DGZ1Q No results +9541 JY8QFUQ01CAE9T unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CAREKGSGPPH#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9542 JY8QFUQ01CYLVO productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame - ctggtgggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9543 JY8QFUQ01AWS2C No results +9544 JY8QFUQ01AIFBN No results +9545 JY8QFUQ01B4AHX productive Homsap IGHV3-7*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame + cctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccgag +9546 JY8QFUQ01DVOVU unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9547 JY8QFUQ01DG2HL productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 863 89.3 192/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + ttcgggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttccttcccccagg +9548 JY8QFUQ01C8AA1 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 934 93.43 199/213 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [X.17.38.11] CARRPAAGSHFALDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ggatacaactttgacaccgattggatcgcctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctgctgactctgataccagatacagtccgtccttccaaggccaagtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagcggcctgaaggcctcggacaccgccatctattattgtgcgaggcgtccagcagctggtagccacttcgctttggacgtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9549 JY8QFUQ01C9MY3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 14 8.8.14 [1.16.38.11] CAKEGTIVGAAGFGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcacctttagcgactatggcatgacctgggtccgccaggctccagggagggggttggagtggtcgcatctattaatgccggtggtagtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgggcagcctgggagccgaagacacggccgtatattactgtgcgaaagaaggcaccattgtgggagctgccggatttggctactggggccagggaaccctggtcaccgtctcctcaccctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9550 JY8QFUQ01A0LZ5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame + ctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaagggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +9551 JY8QFUQ01DCRJC unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD3-16*02 F 3 8 7 X 8.7.X [4.17.38.11] CARGAPFS**# out-of-frame + stop codons ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaggggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9552 JY8QFUQ01CQCZQ No results +9553 JY8QFUQ01C6WRE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 802 85.39 187/219 nt 84.02 184/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 2 8 8 16 8.8.16 [2.17.38.11] CAKVWIELWSAGDHFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'T' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); gcctctggattcGatatttactagatatgccatgacctgggtccgccaggctccAagggaagggtctggagtgggtcgcttctatcagtggtagtgggattagTgaaaaagtacgcagacggcgtggagggccgattcaccatctccagagacagttccgagagaacactgtatctacaaatgaacagcctgagagtcgaggacacggccacatattattgtgcgaaagtatggatagagttatggtcggctggggaccactttgacaactggggccagggaaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9554 JY8QFUQ01A16XV productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9555 JY8QFUQ01CWG23 No results +9556 JY8QFUQ01CXUBO No results +9557 JY8QFUQ01CEYB6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9558 JY8QFUQ01CDH2X unproductive (see comment) Homsap IGHV3-9*01 F (see comment) 892 89.5 196/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [2.17.38.11] *KDRGSSSKYYFDYW in-frame - stop codons Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcacctttgatgattatgtcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggggaagtgctcatatacactatgcggactctgtgaaggaccggttcaccatctccagagacaacgccatgaactccctttatttgcaaatggacagtctgagagctgacgactcggccttgtatttgtaaaaagatcggggtagcagttccaagtattactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9559 JY8QFUQ01BRBV4 unproductive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [1.17.38.11] CARGSYWHYDTFGDY## out-of-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattgggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +9560 JY8QFUQ01AOOQB productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 807 85.45 188/220 nt 85.0 187/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggtgactccatcagtagtactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9561 JY8QFUQ01C5IDJ No results +9562 JY8QFUQ01COOBL No results +9563 JY8QFUQ01BIXBK No results +9564 JY8QFUQ01CFGTC No results +9565 JY8QFUQ01BJLD5 productive (see comment) Homsap IGHV4-61*02 F (see comment) 632 76.47 169/221 nt 76.02 168/221 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 2 10 7 16 10.7.16 [1.17.38.11] CARERDKSGGGAHDFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (76,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); tctccggtgggcccatcatcactggttactcctcttggacatggatccggcagtccgccggtaagggactggagtggatcggacatatttaccaaggtgggatcaccaattacagtccctccttcaggGggccgagtgaatatgtcggtggactcgtccagggggcagttttccctcagtctgcggtctgtgaccgtcgcagacacggccatctattactgtgcgagagaacgtgataagtcgggcggcggagcgcacgactttgattcctggggccagggaaccctagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9566 JY8QFUQ01ARW22 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9567 JY8QFUQ01BA02U productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttaCctggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9568 JY8QFUQ01BFJ67 productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 845 88.37 190/215 nt 86.98 187/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARADYYDTSAYYLDAFDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 60 of V-REGION: 9 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) cctctgggtacagcttcggaggctctgtTtttgcactgggtccgccaggcttccgggaAaaggactggagtgggttggccgtgtcggaaggcagggcgcgacaacatacgctgcgtcggtgaaaggcaggttcctcatctccagagatgatccagcgaacacggcttatctggaaatgaacagcctgaaaaccgaggacacggccgtctattactgtgctcgcgcagattactatgatactagtgcttattatctcgatgcttttgatatctggggccaggggacaattgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9569 JY8QFUQ01AUXOH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + ctctggattcacctttagcatctattccatgagctgggcccgccaggctccagggaaggggctggagtgggtctcatctattaatgataatggtgatagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9570 JY8QFUQ01BGU0C productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 850 88.43 191/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [2.17.38.11] CAREFRAPSLARYGMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctcgggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9571 JY8QFUQ01BQ3Q6 No results +9572 JY8QFUQ01BQTHQ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9573 JY8QFUQ01AYDQU No results +9574 JY8QFUQ01BXFKE No results +9575 JY8QFUQ01A063J unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 915 90.91 200/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-8*02 F 3 10 7 X 10.7.X [1.17.38.11] CARLTDWWGV#FDHW out-of-frame + ctctggtggctccatcagcggtacttctcattactggggctgggtccgccagcccccagggaaggggctggagtggattggcagtatctactctggtgggaccacctactacaacccgtccctcaagagtcgactcaccatgtccgtcgacacgtccaagaaccagatgtccctgcggctgagctctgtgaccgccgcagacacggctgtctattactgtgcgagactgacagactggtggggggtcactttgatcactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +9576 JY8QFUQ01BEN7B unknown (see comment) Homsap IGHV1-3*01 F (see comment) 736 83.1 177/213 nt 82.63 176/213 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.16.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (83,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) tggatacagcttcactaatcacattatccattgggtgcgccaggccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9577 JY8QFUQ01DFFFS productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1004 95.87 209/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +9578 JY8QFUQ01AXPMT No results +9579 JY8QFUQ01CPY5S productive (see comment) Homsap IGHV3-21*04 F (see comment) 741 83.18 178/214 nt 82.71 177/214 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD3-16*01 F 1 8 7 15 8.7.15 [1.17.38.11] CAKRLTVSSKFAAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) caccggattcactttcagtagttttggcatggcctgggtccgccaggctccagggaagggactggagtgggtcgcagacgttgttagtcctcgcagtatatattatgcagactccgtgaagggccgattcatcatctccagagacaacaacaataacaccgtgtacctgcaaatgaacagcctgaggggcgacgacacggccacatattactgtgcgaaacgtctgacggtgtcttcgaaattcgctgcttttgatgtttggggccatgggacagtggtgaccgtctcttcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtcccaggggcttcttcccccag +9580 JY8QFUQ01CHDGD productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9581 JY8QFUQ01CL5FZ unproductive Homsap IGHV3-43*01 F 949 93.52 202/216 nt Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD3-16*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGSYGSYGSDAFDF# out-of-frame + Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) tctggattcatatttgaagactataccatgcactgggtccgtcaagctccggggaagggtctggagtgggtctctcttattaattgggatggtggtaacacatactatgcagactctgtgaagggccgattcaccatctccagagacaacaacaagaactccctgcaaatgcaaatgaacagtctgagaactgacgacaccgccttgtatttttgtgcaaagggctcctacgggagttatgggtccgatgcctttgatttttggggccaaggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9582 JY8QFUQ01BI9VQ productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); gtctggattcaccttcagtgaccatggcatgcactGgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9583 JY8QFUQ01B4U8S No results +9584 JY8QFUQ01AYY7V productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + cctctggactcagtttcactaacgcctggatgagctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaaagatgggaacgtggtcgtcgcatgcctggtccagggcttctt +9585 JY8QFUQ01CAC4E unproductive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1093 98.67 222/225 nt Homsap IGHJ1*01 F 260 100.0 52/52 nt Homsap IGHD1-26*01 F 1 10 9 X 10.9.X [1.17.38.11] CARDRG*WELRAFDPRDET#AEYFQHW out-of-frame + stop codons tccggggacagtgtctctaggaacagtgctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtatctgtgaaaagtcgaataaccatcaacccggacacatccaagaaccagttctccctgcagctgaagtctgtgactcccgaggacacggctgtgtattactgtgcaagagatcggggatagtgggagctacgtgccttcgatccccgcgacgaaaccccgctgaatacttccagcactggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9586 JY8QFUQ01CG01D unproductive (see comment) Homsap IGHV1-2*02 F 902 91.98 195/212 nt 91.51 194/212 nt Homsap IGHJ2*01 F 211 88.68 47/53 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [0.17.38.11] CARAPVGWYFDLW in-frame + stop codons in CDR2-IMGT, from codon 58 of V-REGION: 2 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) tggatacaccttcaccggctactatatgtactgggtgcgacaggcccctggacaagggcttgagtggatggcaaagatcaacctaaagtggtgccacagactatgcacagagttttcagggcagggtcaccttgaccagggacatgtccatcaccacagccaccatggagctgagcagtctgagatctgacgacacggccgtgtattattgtgcgagagcccccgtggggtggtacttcgatctctggggccgtggcaccctggtcactgtttcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9587 JY8QFUQ01BP1UC productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9588 JY8QFUQ01AVNRN unproductive Homsap IGHV3-48*04 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSDFLLDG#YW out-of-frame + in FR2-IMGT at codon 39 of V-REGION: 'T' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); ctctggattcacctttactagttacagttTtcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcagactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtttttgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgattagtagtgattttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9589 JY8QFUQ01AZNRP productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*05 F 975 95.33 204/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 3 8 8 21 8.8.21 [0.17.38.11] CAGDRGPVFRVVHIGQIYGLDVW in-frame + tggatacaccttcaccaactactatcttcactgggtgcgacaggcccccggacaagggcttgagtggatgggacggatcaacccaaacagtggtggcacaacctatgcacagaagtttcagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgagcaggctgagatctgacgacacggccgtctattactgtgcgggagatcggggtccggtttttagggtggttcatataggccaaatctacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcacctgcctggtcagggcttcttccc +9590 JY8QFUQ01C9RTB productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1001 95.02 210/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 2 10 7 12 10.7.12 [1.17.38.11] CVRHRRLELLPDYW in-frame + tctctggtgactccatcagcagtaatagtttctactggggctggatccgccagcccccagggaaggggctggagtggattgggaatatctattatagtgggagcacctactacaacccgtccctcgagagccgagtcaccatatccgtagatacatccaggaaccagttctccctgaagctgaggtttgtgaccgccgcagacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +9591 JY8QFUQ01A8HEJ unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD4-23*01 ORF 1 8 7 X 8.7.X [1.17.38.11] CARLTTAVGGWS#FDIW out-of-frame - stop codons tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtctttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +9592 JY8QFUQ01B9CL3 No results +9593 JY8QFUQ01BLCOT productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 1024 98.12 209/213 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-2*02 F 2 8 7 15 8.7.15 [1.17.38.11] CARGVGVSWHTEYFQHW in-frame + tctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagaggggtcggcgtcagctggcatactgaatacttccagcactggggccagggcaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctagtccagggcttcttccccca +9594 JY8QFUQ01BEW1W No results +9595 JY8QFUQ01CVNA8 productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9596 JY8QFUQ01DKFMG unproductive (see comment) Homsap IGHV3-48*01 F 855 88.48 192/217 nt 87.56 190/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.16.38.11] CARASTFYYDGSGYRDA#FDIW out-of-frame - stop codons in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggcttcagtttgagtacttataccatgGaactgggtccgccaggctccaggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgctttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9597 JY8QFUQ01CP1NK No results +9598 JY8QFUQ01C8ZP6 unknown (see comment) Homsap IGHV3-21*04 F (see comment) 667 78.54 172/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (78,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctccggtttcatcttcagtcacttcagcatgaactgggtccgccaggctccaggaaagggcctggagtggatcgccgacatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcgacgatacggccacctattattgtgtgaggctcttcaccagcgatggagtgagaggcgactactgggggccagggcgcccgggttctcgtctccgcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9599 JY8QFUQ01ALJNM productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 668 79.72 169/212 nt 78.77 167/212 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [0.17.38.11] CVRDAETTVSGVAGWFDPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 56 to 57 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) ctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaAGggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9600 JY8QFUQ01BXEXG productive (see comment) Homsap IGHV4-39*02 F 933 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-9*01 F 1 10 7 18 10.7.18 [1.17.38.11] CARLLRVYDWYSQRGYFDTW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctccgatggctccatcagcactagtaattactactggggctgggtccgccagcCccccagggaaggggctggagtggattggaagtatatattatagtgggagcaccgactacagctcgtccctcaggagtcgcgtcaccatatccagagacacgtccaagaaccacttctccctgaaggtgacctctgtgaccgccgcagacacggctatatattactgtgcgagactcttacgggtttatgactggtacagtcaaaggggttacttcgacacctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9601 JY8QFUQ01CWWDM productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame + ctctggattccccttcagcacctatcccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +9602 JY8QFUQ01C7R6J No results +9603 JY8QFUQ01B9XZC No results +9604 JY8QFUQ01AOTW1 unproductive Homsap IGHV3-74*03 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-20*01 F 3 8 8 X 8.8.X [1.16.38.11] CVREKVVIGT#WFDTW out-of-frame + in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagccactggatgcactgggtccgccaaggtatagggaggggctggtgtggcttgcacgcattaacagtgatggcagtagtacagcttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaagacgctttatctgcaaatgaacagtctgagagtcgaggacacggctgtctattactgtgtaagagagaaagtagtaattggaaccgctggttcgacacctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9605 JY8QFUQ01CMQSO productive Homsap IGHV3-72*01 F 1088 98.66 221/224 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-15*01 F 1 8 10 8 8.10.8 [1.17.38.11] CLRPPRYDPW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9606 JY8QFUQ01A84F3 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1015 97.65 208/213 nt 96.24 205/213 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CARLGSGG*SWL#YADYW out-of-frame - stop codons in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 75 of V-REGION: 'CG' (2 nucleotides at position 127 to 128 in the user submitted sequence), (cause frameshift); tctggtggctccatcagtagttactactggagctggatccggcagGcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacAaacccctccctcaagagtcCGgggtcaccatgtcagtggacacgtccaagaaccagttctccctgaagctgagctctctaaccgctgcggacacggccgtgtattactgtgcgagactagggtccggggggtagtcgtggttattacgctgactactggggccagggaacccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +9607 JY8QFUQ01ARFI3 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKKKHYNSGTYLYNFDY## out-of-frame + ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaaagcattataattcggggacttatttatacaactttgactactggggccgggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +9608 JY8QFUQ01CLVA4 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F 335 88.37 76/86 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 X X 10 X.X.10 [X.X.28.11] CARLGQLALDYW in-frame + tcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9609 JY8QFUQ01AYITE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcanttccccgaaccggtgacggtgtgcgtggaactca +9610 JY8QFUQ01C60RS unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - stop codons cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtaggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccaattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9611 JY8QFUQ01B9S8O productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame - gttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9612 JY8QFUQ01ARMUC productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggaTttgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +9613 JY8QFUQ01BDPSL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 87.56 190/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKYVEGWSYTGGYYNSYAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'AT' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); ttctggattcgcctttagccggttATggccatgacttgggtGccgccagactccagggagggggctggagtgggtctcaggtctcagtggtagtggtgatagcacatactactcaaactccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggaggggtggtcatatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9614 JY8QFUQ01CAQ7C productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9615 JY8QFUQ01CF1GZ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARAGYCNNGVCYSSYFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggatttaccttcagtagctactggatgcactgggtccgccaagctccggGggaaggggctggtgtgggtctcacgtatgaatagtgatggcagtgacataaggtacgcggactccgtgaggggccgattcaccatctccagagacaacaccaagaacacgctgtatctacaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagcgggatattgtaataatggtgtatgctactccagttactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9616 JY8QFUQ01AY45M productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [1.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) gttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9617 JY8QFUQ01C0LUF productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 840 88.32 189/214 nt 87.38 187/214 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD1-1*01 F 3 8 7 16 8.7.16 [1.17.38.11] CARDSHKSTDGDLYFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'CAGT' (4 nucleotides at position 82 to 85 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift); ttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggccccagggaaggggccggagtgggtctcagttatCAGTggttgggggtaatactatatattatgcagactccgtgagaggccggttcaccatctccagagacaactccaagaacatgctgtatctgcaaatTgaatagcctgagagccgaggacacggccgtttattactgtgcgagagactcccacaaatccaccgacggtgacttgtactttgactactggggcccagggaacccgggctcaccgtctcctcagcatccccggaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaatg +9618 JY8QFUQ01BVVXG No results +9619 JY8QFUQ01DF7O5 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatCgggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttcccctggcgcctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9620 JY8QFUQ01ATAZY No results +9621 JY8QFUQ01BVA4N productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARKRVPGGTFYGDYW in-frame - agcctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9622 JY8QFUQ01BGC57 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 895 90.74 196/216 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame + tctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggct +9623 JY8QFUQ01AXX7W unproductive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-22*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDGPPYLYGSHGNSFDQW# out-of-frame + stop codons in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtgggggcccagggaaccctagtcaccgtctcctcagcctccaccaaggggccccatcggtcttcccctgacgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9624 JY8QFUQ01AO52M productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 746 83.26 179/215 nt 82.79 178/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tttcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgatggtgtcgtggaactc +9625 JY8QFUQ01CZ7K3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.37.11] CVSDLAGQKGFW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9626 JY8QFUQ01CFCPT No results +9627 JY8QFUQ01ARJZT unproductive (see comment) Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGHW in-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaacttcagaacctattagatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +9628 JY8QFUQ01C73AJ No results +9629 JY8QFUQ01CNEC8 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 82.79 178/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagccCcccagggaagggactggagtggattgGgggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9630 JY8QFUQ01CM68E productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9631 JY8QFUQ01AKSQR productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggagaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacacgcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +9632 JY8QFUQ01C4C8I No results +9633 JY8QFUQ01B439T productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9634 JY8QFUQ01A2EVT unproductive Homsap IGHV3-48*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.16.38.11] CARGQNGYKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccaggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaatggctacaagtgcttcactggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9635 JY8QFUQ01B3Y5F No results +9636 JY8QFUQ01A9HIP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 829 86.76 190/219 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CVKEDHDSGLRVLLEW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ggctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9637 JY8QFUQ01DS8Q6 unknown (see comment) Homsap IGHV1-58*01 F, or Homsap IGHV1-58*02 F or Homsap IGHV3-11*01 F or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-16*01 ORF or Homsap IGHV3-16*02 ORF 65 100.0 13/13 nt 3 X X 3.X.X [1.X.X.X] null - No rearrangement found tctggattcacct +9638 JY8QFUQ01C5NQN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.53 193/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [2.16.38.11] CAKDASRYYYNSYCDNW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 212 to 212 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gcctctggattcacctttaccaactacgccatgagctggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttaCtttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9639 JY8QFUQ01AS3G0 unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F (see comment) 620 76.28 164/215 nt 8 8 X 8.8.X [0.17.38.X] null + No rearrangement found Low V-REGION identity (76,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9640 JY8QFUQ01A6LJQ productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9641 JY8QFUQ01B9J90 unproductive (see comment) Homsap IGHV3-11*01 F 1053 98.62 214/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDSSTTVTKDYW in-frame + stop codons ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggtagtggtaataccatatactacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtttctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagattcctcgactacggtgactaaagactactggggctagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9642 JY8QFUQ01BBKH9 productive Homsap IGHV3-11*01 F 1012 96.76 209/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 142 76.0 38/50 nt Homsap IGHD6-6*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARDMYSSSALFPW in-frame + tctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtttcacacattagtagtagtggtagtatcataaactatgcggactctgtgaagggccgattcaccatctccagggacaacgccaagaattcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatatgtatagcagctcggcccttttcccttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9643 JY8QFUQ01DWIV2 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 932 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9644 JY8QFUQ01AHS4R No results +9645 JY8QFUQ01DCY6I productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 997 96.26 206/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFYYW in-frame - tggatacaccttcaccagctactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggnggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagacttttactactggggccagggaaccctggtcaccgtcccctcagcatccccgaccagccccaaggtctttccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +9646 JY8QFUQ01C6EVL unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*05 F (see comment) 307 75.45 83/110 nt 8 10 X 8.10.X [1.17.X.X] null - No rearrangement found Low V-REGION identity (75,45% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcactttcagtgacgcctggatgagctgggtccgccagattccagggaaggggctggagtgggttggtcgtcgcatgcctggtccagggcttcttccccca +9647 JY8QFUQ01CWX3I unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 102 55.24 58/105 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons ctctggattcaccttcagtcgttatagcatgaactgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +9648 JY8QFUQ01CZAMZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame + cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9649 JY8QFUQ01BHJ6Q productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9650 JY8QFUQ01ADX32 No results +9651 JY8QFUQ01A19MC No results +9652 JY8QFUQ01AX2V4 No results +9653 JY8QFUQ01AFFCS productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatcgtcttccccctgcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcagg +9654 JY8QFUQ01A9PP5 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKEQEPHGHYVGTDYW in-frame + cgtctggattcaccttcagtagctacggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggccgtgtattcctgtgcgaaagaacaagaaccacatgggcattatgttggaactgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +9655 JY8QFUQ01C5X96 productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9656 JY8QFUQ01CQFWM productive (see comment) Homsap IGHV3-48*01 F 1070 100.0 215/215 nt 99.07 213/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.37.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 90 of V-REGION: 1 nucleotides (from position 174 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9657 JY8QFUQ01AJF1Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARFGPLTRPDYWG in-frame + cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccaggggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9658 JY8QFUQ01AYOSL productive (see comment) Homsap IGHV3-9*01 F (see comment) 793 84.93 186/219 nt 84.02 184/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [2.17.37.11] CVKDMVAGQGLLSRFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'TTTT' (4 nucleotides at position 61 to 64 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 114 in the user submitted sequence), (cause frameshift) agcctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaaTTTTgggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatgggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9659 JY8QFUQ01B4V0R No results +9660 JY8QFUQ01BB08I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9661 JY8QFUQ01ANU4J productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9662 JY8QFUQ01C9RK7 No results +9663 JY8QFUQ01DOBUG unproductive (see comment) Homsap IGHV3-48*03 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame + stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); ctctggattcacctttactagttaCagttttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca +9664 JY8QFUQ01AUIPM No results +9665 JY8QFUQ01C5770 No results +9666 JY8QFUQ01ACMHQ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 908 91.63 197/215 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 21 8.8.21 [0.17.38.11] CVRVGAPYYDFWSGYQTNWFDPW in-frame + ctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgcaagtactacttccatacattatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggcgccatattacgatttctggagtggctatcagactaactggttcgacccctggggccagggaactctggtcaccgttacctcagcatccccgaccagccccaaggtcttcccgctgacgcctctgcagcaccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +9667 JY8QFUQ01DCLEC unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 149 52.07 113/217 nt 8 8 X 8.8.X [1.17.37.X] null - No rearrangement found cctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgaagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +9668 JY8QFUQ01AN7RR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 781 83.78 186/222 nt 82.88 184/222 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [3.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); caatgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9669 JY8QFUQ01B7CZQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 779 84.4 184/218 nt 83.94 183/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 84 of V-REGION: 'T' (1 nucleotides at position 157 to 157 in the user submitted sequence), (cause frameshift); gtctcggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaTgggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9670 JY8QFUQ01B2FO6 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 831 87.85 188/214 nt 86.92 186/214 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 7 8 17 7.8.17 [1.16.38.11] CARDSGSSEYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift) tctggattcagcttaagttctatggcatgaactggtccgccagcgtccatggggggggctggagtgggtctcattcattaacagtattagtagttataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9671 JY8QFUQ01AHY6R productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD2-15*01 F 2 8 8 21 8.8.21 [1.17.38.11] CAKTGGQCSGGNCYLHYYGMDVW in-frame + ctctaaattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcacaggtattagtggtggtggtgaaaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagagcatgttgtatctgcaaatgaacagcctgagagccgaagacacggccgtattttactgtgcgaaaactggcggtcaatgcagtggtggtaactgctatttgcactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +9672 JY8QFUQ01CW8LP productive (see comment) Homsap IGHV3-15*04 F 1006 95.05 211/222 nt 93.24 207/222 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.16.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 200 to 200 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtggttggccgtattgCcaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaaGtatgctgtatctgcaattgaacagcctgaaaacCcgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9673 JY8QFUQ01A8CRV productive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9674 JY8QFUQ01A67RJ unknown (see comment) Homsap IGHV1-2*02 F (see comment) 462 68.22 146/214 nt 67.76 145/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (68,22% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9675 JY8QFUQ01CRXKV productive Homsap IGHV4-61*02 F 798 85.0 187/220 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSSSIGGERELDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gtctggtggccccatcagcagtagtggcttcgcctggacctggatccggcagaccgccgggaagggactggagtggatcggacgtgtttatggtagtgggaataccaattacagtccttccctccagagtcgagtcaccatatcagtagagacgtccaagaatcagttctccctgaggttgacttctgtgaccgccgcagacacgggcctatattactgtgcgagagaacatagtagttcgattggcggagagagagaacttgactcctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9676 JY8QFUQ01B0BI5 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9677 JY8QFUQ01AGMY9 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1016 96.76 209/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [1.16.38.11] CAKDRITIFSYNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift) ctctggattcacctttagcagctatgccatgagctgggtcgccaggntccagggaaggggctggatgggtctgcagcGtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9678 JY8QFUQ01CUV36 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F (see comment) 785 84.16 186/221 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-9*01 F 2 10 7 11 10.7.11 [1.17.38.11] CARILDGYFFDPW in-frame - Low V-REGION identity (84,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcgacactcaaaattactactggggctggattcgccagcccccagggacgggactggagtgggttggcagtgtccgctatggcgagagcacctattacaacccgaccctcaaaagtcgactcaccatatccatagacacgtccaggagccagttatccctgagactgagttctgtcaccgccgccgacacggcagtttactactgtgcgaggatcttggatggttacttcttcgacccctggggccagggaacccacgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9679 JY8QFUQ01DE83A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9680 JY8QFUQ01AZBQJ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1041 96.83 214/221 nt 95.93 212/221 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [2.17.38.11] CAKDRITIFSYNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); cagcctctggattcacctttagcagctatgccatgagctgggtccgGccaggntccagggaaggggctggatgggtctgcagcGtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9681 JY8QFUQ01CCVXJ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - agcctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9682 JY8QFUQ01C6ZDR productive Homsap IGHV4-61*02 F 879 89.09 196/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.38.11] CARDFGGSYNLVAYW in-frame + ctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9683 JY8QFUQ01BK9PA productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt 84.79 184/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CVKDYGNCAGGRCYSIPLDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'TTT' (3 nucleotides at position 98 to 100 in the user submitted sequence), (do not cause frameshift); ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtggtgggTTTttgacatactacgcagacgccgtgcagggccggtttattatttccagagacgattcccagaacacgatagatctgcaaatgaacaatttgagagccgacgacacggccatctattactgtgtgaaagattacggcaattgtgctggtggtcgctgctactcgattccccttgactattggggccggggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacaaccacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +9684 JY8QFUQ01B6DWD productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1043 96.43 216/224 nt 95.98 215/224 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 10 17 8.10.17 [1.17.38.11] CTRDNPPLRSLEWLPFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 97 of V-REGION: 'G' (1 nucleotides at position 201 to 201 in the user submitted sequence), (cause frameshift); cttctggattcacctttggtgattatagtatgagttggttccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcaaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccGggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9685 JY8QFUQ01DCOUL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggattcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9686 JY8QFUQ01DM3S0 No results +9687 JY8QFUQ01A5K3B productive (see comment) Homsap IGHV1-3*01 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARGRYDISGRGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); tggatacaccttcactagttTttagtatacattgggtgcgccaggcccccggacagaggcttgagtggatgggatggatcaacgcaggcaacggtcacacaaaatattcacagaagttccaggacagagtcaccattataagggacacatccgcgagcacagcctacatggacctgagcaccctgagatctgaagacacggctgtctattactgtgcgagagggcgctatgatattagtggtcgtggccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +9688 JY8QFUQ01B8WRM productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*06 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [1.16.38.11] CARGDGYNFGGLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 42 in the user submitted sequence), (cause frameshift) tctggattcaacttcataggttatggcatgcactgggtccgcaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactccgtgaggggccgatccatcatttccagagacgattctaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9689 JY8QFUQ01BZD8Y productive Homsap IGHV3-48*01 F 815 86.24 188/218 nt Homsap IGHJ6*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 1 8 8 8 8.8.8 [1.17.38.11] CVRGAGLDVW in-frame - cctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaggggctggagtgtgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctggacgtctggggccaagggaccacggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9690 JY8QFUQ01DNUOM productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); tatatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggCaaatcaatcacagtggaagccccaactacagcccgtccctcaatagtcgagtcatcatatcgatagacacgtccaagaaccaggtctccctgaagctcttctctgtgaccgccgcggacacgggtgtgtactattgtgcgaggcccacgtatagtagcggccgggacgcctttgatacctggggccaagggacgacggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9691 JY8QFUQ01CSQCS unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 473 68.35 149/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (68,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9692 JY8QFUQ01CKPM2 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 931 92.59 200/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 86 of V-REGION: 'C' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 78 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggcgtggagtgggtctctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactCccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9693 JY8QFUQ01BP3KJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9694 JY8QFUQ01A5H4Z unproductive Homsap IGHV3-66*02 F 893 91.51 194/212 nt 90.57 192/212 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [1.16.38.11] CAKLADTGEWSNRIFI#W out-of-frame - in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) ctctggattcaccgtcagtagcagcttcatgacttgggtccgccagctccaggaaaggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatctttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9695 JY8QFUQ01CWE2H No results +9696 JY8QFUQ01BNPBU unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 121 69.81 37/53 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVVWSLWYFDL## out-of-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctgggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9697 JY8QFUQ01CX7MG No results +9698 JY8QFUQ01CKBGY productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame - ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcatctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9699 JY8QFUQ01BID64 No results +9700 JY8QFUQ01C0N7I productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9701 JY8QFUQ01A0N2E productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARVRGGLSSGWYESLDYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagttcgaggaggtcttagcagtggctggtacgagtctcttgactactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaaccc +9702 JY8QFUQ01DIJMJ unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1110 100.0 223/223 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFFGLL# out-of-frame + stop codons ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9703 JY8QFUQ01BLIOS No results +9704 JY8QFUQ01AL0GQ unproductive (see comment) Homsap IGHV3-11*01 F 902 91.98 195/212 nt 91.04 193/212 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [0.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - stop codons in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) tctgattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggAtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagaactacttccccgaaccggtgacggtgtcgtggaactcag +9705 JY8QFUQ01B5NOR productive (see comment) Homsap IGHV1-18*01 F 876 90.19 193/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARGDIMYYYNSGPFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); tggttacGagtttttccagttatggtatcaattgggtgcgacaggCcccctggacaagggcttgagtggatgggatggatcagcggttacaatggtaacacaaattttgcacagaagttccagcatagagtcaccctgactacggacacatcaacgaggacagcctacatggagctgaggagcctgacatttgacgacacggccgtatattactgtgcgagaggggacattatgtattactataattcgggcccctttgagtactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9706 JY8QFUQ01BL2RY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + tccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +9707 JY8QFUQ01CXL6W No results +9708 JY8QFUQ01CGJGT No results +9709 JY8QFUQ01DNT9I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9710 JY8QFUQ01B4F4X productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1007 96.74 208/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAREDGSGRRHFDYW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccaggaaagggactggagtggattgggtatatcttttacactgggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagaatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9711 JY8QFUQ01CGDXY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9712 JY8QFUQ01CGK5B productive (see comment) Homsap IGHV3-11*01 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9713 JY8QFUQ01C01VG productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9714 JY8QFUQ01AMPM6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9715 JY8QFUQ01DJ5FE unproductive Homsap IGHV4-39*02 F 943 91.89 204/222 nt 90.99 202/222 nt Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD4-17*01 F 1 10 7 X 10.7.X [2.17.38.11] CASVTTVSMRMKY## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 50 of V-REGION: 'GC' (2 nucleotides at position 70 to 71 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagcagtgatagttactactggggctggatccgccagtccccagggaaggggGCtgggagtggaTttgggaatatctattatcgtgggagcacctattacaacccatccctcgagagtcggctcaccatgtcggtagacacgtccaggaacctcttctccctgaggctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagcgtgactacggtgtctatgaggatgaaatactggggccggggaacccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgccgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9716 JY8QFUQ01C49VP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKAGYSSARTHMDIW in-frame - cctctggattcacctttagcaattttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttgtgagtggtagtggcgatagaacagactacgcagactccgtgaagggccggttcactatctccagagacaattccaagagtacactattcctgcaaatgcacagcctgagagtcgaggacacggccgtatattactgtgcgaaagctggatatagtagtgcgcgaacccacatggacatctggggccaaggggtcgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9717 JY8QFUQ01CKUWN unproductive Homsap IGHV3-13*01 F 876 90.19 193/214 nt Homsap IGHJ2*01 F 121 69.81 37/53 nt Homsap IGHD6-13*01 F 2 8 7 X 8.7.X [1.17.38.11] CAKVVWSLWYFDL## out-of-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctgggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9718 JY8QFUQ01AYHQY productive (see comment) Homsap IGHV3-7*01 F 1004 95.87 209/218 nt 95.41 208/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 7 8 11 7.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) ggctctggattcagcttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9719 JY8QFUQ01C3HDP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9720 JY8QFUQ01AIKH9 No results +9721 JY8QFUQ01CCJXU productive (see comment) Homsap IGHV1-69*06 F, or Homsap IGHV1-69*14 F 853 89.2 190/213 nt 88.73 189/213 nt Homsap IGHJ6*02 F (see comment) 229 85.48 53/62 nt Homsap IGHD4-17*01 F 2 8 8 18 8.8.18 [0.16.38.11] CARSDFGAYPTYYYYFMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 73 in the user submitted sequence), (cause frameshift) tggaggcaccttcagtagttacgcaatcagctgggtgcgacaggcccctgggcaagggcttgagtggatggggggatcatccctaagtttggaagaacaaactacgcacagagtttccagggcagagtcacgattaccgcggacaaatctacgaggacagtctacttggagttgagtagcctgcgatctgaagactcgggcgtgtatttctgtgcgaggagtgacttcggggcctaccctacatactactactactttatggacgtctggggccgtgggaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtctcgcctgcctggtccagggcttcttccccca +9722 JY8QFUQ01A2UAC productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame - Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +9723 JY8QFUQ01BQ8M2 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9724 JY8QFUQ01AY8UC productive Homsap IGHV3-7*03 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame + cctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9725 JY8QFUQ01BYN0U productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [0.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactca +9726 JY8QFUQ01CM8A1 productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagtacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9727 JY8QFUQ01BBSMN productive Homsap IGHV4-4*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARTGYTLAVGVREFDSW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01BBSMN ; 8 AA in Homsap_IGHV4-4*07), and low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggcggccccgtcaccaataatgattactactggagttggatccgacagcccgccgggaagaaactggagtggctcgggcgtatttttggaagtgggaccaccaattccaatccctccctcaggggtcggctcaccatgtcactagatccgtctaagaatcagttcaccctgaggttgacctctgtgaccgccgcggacacggccgtgtattattgtgcgagaactggttatactctcgctgttggagtgcgagagtttgactcctggggccagggaaccttggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9728 JY8QFUQ01DEYU2 productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9729 JY8QFUQ01AXOBA productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9730 JY8QFUQ01BB67V productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 832 87.5 189/216 nt 86.57 187/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 7 12 8.7.12 [2.17.38.11] CARAPGWMNPFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'T' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); gtctccggtggctccatcaccacttactacatcagctggctccggcaGgcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaacTccctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9731 JY8QFUQ01CU4ET unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWGELSL#DYW out-of-frame - stop codons ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9732 JY8QFUQ01C6PDY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9733 JY8QFUQ01DNE8U productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatcccgaccagccccaaggtcttcccgctgagcctctgnagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9734 JY8QFUQ01CLJ2C productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9735 JY8QFUQ01CTQJD unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 772 84.98 181/213 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F 69 60.42 29/48 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CARERGSGPPHRHGRL# out-of-frame - Low V-REGION identity (84,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccatctactactgtgcgagagaaagaggttcggggcccccccacaggcatggacgtctgggggcccagggaccatggtcaccgtctccctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9736 JY8QFUQ01C9T1K productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-6*01 F 1 8 8 11 8.8.11 [1.17.38.11] CAKVDSSSAWDYW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaagtttcatgaatatgccatgatctgggtccgccaggctccaggcaagggtccggaatgggtctcgtctattagtagtactagtaaatacatctattatgcacagtcagtggagggccgattcaccatctccagagacgacgccgagaacgcactgttcctccagatgagcagcctgagtgtcgacgacacggctatctattactgcgcgaaagtcgatagcagttcggcctgggactattggggcccgggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9737 JY8QFUQ01B8VUB unknown (see comment) Homsap IGHV3-7*01 F 1031 96.79 211/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttccccca +9738 JY8QFUQ01BNIXY unproductive (see comment) Homsap IGHV1-8*01 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [0.17.38.11] CARGPCQWL#YTDYW out-of-frame + stop codons tggatacaccttcaccagttatgatatcaactgggtgcgacaggccgctggacaagggcttgagtggatgggatgggtgaaccctaatagtggtgccacaggctatgcacagaagttccagggcagagtcaccatgagcagggacacctccgaaagtacagcctacgtggagctgagcagcctgggatctgaggacacggccgtgtattactgtgcgagaggcccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9739 JY8QFUQ01CUQ6W No results +9740 JY8QFUQ01B8REE unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 930 92.99 199/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [0.17.38.11] CVTSGGSGTDLVPP#DDW out-of-frame + tggatacagctttaacaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggactcatctatcctggtgactctgtaaccatgtacagcccgtccttcgaaggccaggtcaccatctcagccgacaaatccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacaccgccacatattactgtgtgacctcggggggttcgggcacagatttggtcccccccggacgactgggcccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +9741 JY8QFUQ01C8RD8 No results +9742 JY8QFUQ01AXSGN No results +9743 JY8QFUQ01AR8PF productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*02 F 3 8 8 19 8.8.19 [1.17.38.11] CARLPFIVVVTGAFLGHFDYW in-frame + ttctggatacatctttaccaattactggctcggctgggtgcgccagatgcccggcaaaggcctggagtggatggggatcatctttcctgctgactctgatgcccgatacagcccgtccttccaaggccaggtcaccatctcaatcaacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacgccgccatatattactgtgcgagactcccctttattgtggtggtgactggtgcgtttttgggacactttgactattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9744 JY8QFUQ01CFYWU unknown (see comment) Homsap IGHV3-7*02 F 118 60.24 50/83 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found cctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9745 JY8QFUQ01AJ19T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9746 JY8QFUQ01BRNZT productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactca +9747 JY8QFUQ01BE9IC No results +9748 JY8QFUQ01AMMAC productive (see comment) Homsap IGHV1-2*04 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 14 8.8.14 [0.17.38.11] CTRDTSLDNGAALDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccgactactatatgcactgggtgcgacaggGccccaggacaagggcttgagtggatgggatggatcaaccctaaaagtggcggcacaaattatgcacggaagtttcagggctgggtcaccatgaccagggacacatccatcaacactgtctacatggagttgagcaggttgaaatctgacgacacggccatttattactgtacgagggatacttctttggacaacggagccgctcttgatatttggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9749 JY8QFUQ01C5B6A productive (see comment) Homsap IGHV3-74*03 F 856 88.13 193/219 nt 87.21 191/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); gcctctggattcacGtttccacacctcctggatgGcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9750 JY8QFUQ01C945U productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*02 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*04 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*08 F or Homsap IGHV3-30*09 F or Homsap IGHV3-30*10 F or Homsap IGHV3-30*11 F or Homsap IGHV3-30*16 F or Homsap IGHV3-30*17 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F (see comment) 210 83.61 51/61 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 2 X X 18 X.X.18 [X.X.20.11] CATDLVTSTPGVLDDAYAFW in-frame - Low V-REGION identity (83,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gaacactgtgtatctgcaaatgaacagtctgagagttgacgactcggctctatatcgctgtgcgacagacttggtgacctccacaccgggagtcctcgatgatgcttatgccttttggggccaagggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9751 JY8QFUQ01BCMCB unproductive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 843 87.27 192/220 nt 86.82 191/220 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 10 7 X 10.7.X [1.17.38.11] CARAWLDPLL*LL# out-of-frame + stop codons in FR3-IMGT at codon 103 of V-REGION: 'G' (1 nucleotides at position 217 to 217 in the user submitted sequence), (cause frameshift); ctctggtggctccgtcagcagtggtaattactactggaactggatccgccaacccccagggaagggactggagtggattggatatatctactatgctggggccaccaacgtcgccccctccctcaagaaccgagtcaccataacgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccgtatattaGctgtgcgagggcgtggctggaccccctactttgactcctggggccagggcaaatctggtcaccgtctcctcagcatccccgaccacgccccaaggtccttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +9752 JY8QFUQ01BZ8ZU unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame + ctccggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggtccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9753 JY8QFUQ01DQY2Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9754 JY8QFUQ01DGCND productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9755 JY8QFUQ01AJ9GQ productive Homsap IGHV4-39*02 F (see comment) 704 80.09 177/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 10 7 15 10.7.15 [1.17.38.11] CAIHNYYGSGRNYFDHW in-frame + Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggagtctccgccatcggcaccagttccttctggggctgggtccgccagcccccagggaaggggctggagtggatcggagctgttcattacagtggaagtatctcttacacgccggccctcaagagtcgactcaccatgtccttagacacgtcaaaaggtcacttgtccctgagactgacctcagtgacctccgcagacacggctatgtactactgtgccatacacaactactatggatcggggagaaactactttgaccactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9756 JY8QFUQ01B6L4V productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSGSSDYTRYDAQDVW in-frame + ctctggattcaccttcagtagttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagccattagcagtattagtcattacatatattacgcggactcactgaggggccgattcaccatctccagagacaacgccaagaacttactgtatttgcaaatgaatagcctgagagccgaagactcggctgtttactactgtgcgagagatagcggctcgtccgactacactaggtacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca +9757 JY8QFUQ01DWYGA No results +9758 JY8QFUQ01BESUC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame + tctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9759 JY8QFUQ01DECYW No results +9760 JY8QFUQ01A2L8B unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [2.17.38.11] CARPGGIAYCSGGSCYDPW# out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaTcctttagtagctatgccatgggctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9761 JY8QFUQ01C9Q2U unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 276 90.91 60/66 nt 89.39 59/66 nt 8 X X 8.X.X [1.3.9.X] null + No rearrangement found in FR2-IMGT, from codon 42 of V-REGION: 75 nucleotides (from position 38 in the user submitted sequence), (do not cause frameshift) ttctggattcaccttcagtagttatagcatgaactgggactcagtgaagggccgattcaccttggt +9762 JY8QFUQ01DKE6B unproductive Homsap IGHV4-61*02 F (see comment) 974 93.21 206/221 nt 92.76 205/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 X 10.7.X [1.17.38.11] LVREIPLIAIRTSI#DYW out-of-frame + Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaacagtggtagttactactggagttgggttcggcagcccgccgggaagggactggagtggattgggcgtatctacaccagtgGggagcaccaactacaacccctccctcaagagtcgagtcgccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctattttttggtgcgagaaatccctcttatagcaattcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +9763 JY8QFUQ01BLV8R productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1046 97.29 215/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9764 JY8QFUQ01A6VGQ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +9765 JY8QFUQ01CAB6L productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9766 JY8QFUQ01A33GI No results +9767 JY8QFUQ01A7BEI No results +9768 JY8QFUQ01ARSQJ No results +9769 JY8QFUQ01CXYJH productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9770 JY8QFUQ01DFNMK No results +9771 JY8QFUQ01A9LCA unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 94 52.24 70/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactggatccgccaagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9772 JY8QFUQ01C996D unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 655 90.51 143/158 nt 89.87 142/158 nt 8 8 X 8.8.X [0.17.19.X] null - No rearrangement found in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 75 to 77 in the user submitted sequence), (do not cause frameshift); cgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaac +9773 JY8QFUQ01BMA6K unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYLNL#DYW out-of-frame + in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggcCtggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatatttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9774 JY8QFUQ01BZ27M unproductive Homsap IGHV1-8*01 F, or Homsap IGHV1-8*02 F 1011 97.2 208/214 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [0.17.38.11] CARGVRTVVTALSYGMDV## out-of-frame + tggatataccttcaccagatatgatatcaattgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaacagtggtaacacaggctatgcacagaagttccagggcagagtcatcatgaccaggaacacctccataagcacagcctacatggagctgagcagcctgagttctgaggacagggccgtgtattactgtgcgagaggtgtccgaacggtggtgactgctctttcctacggtatggacgtctggggcccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggctt +9775 JY8QFUQ01C4TA5 unproductive Homsap IGHV3-74*03 F 1026 97.24 211/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 124 72.0 36/50 nt Homsap IGHD2-8*01 F 1 8 8 X 8.8.X [1.17.38.11] CATGPDYAYAM## out-of-frame - ctctggattcaccttcagtcgctactggatgcactgggtccgccaagctccagggaagggcctggtgtgggtctcacgtattaaaagtgatgggattagcacaacgtacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtactactgtgcaaccgggcccgattatgcgtatgctatgtgggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9776 JY8QFUQ01DJFIZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 693 80.18 174/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD5-12*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKSPDSGYDSNWLDPW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaacttggcgaagttcgccatgagctgggtccgccaggctcctgggaaggggctggagtgggtctcagagatcagtggctccggtagtaaagtcggatatgcggagtccgtgaagggccgattcaccatctccaaagacaattccaagaacacattgtacttgcaaatgaccgacctgagacccggcgacacggccatttattactgtgcgaaaagtcctgatagtggctacgattctaactggctcgacccctggggcctgggaaccctggtcaccgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9777 JY8QFUQ01CV97H productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [0.17.38.11] CAARIDSGHYWNAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); ctggatacagatttCaccaactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctggtgactctgatacccggtacaacccgtccttccaaggccaggtcaccttctccgtcgacaagtccatcaacaccgcctacctgcagtgggacagcctgaagacctcggacaccgccaagtattactgtgcggcgagaattgatagtggtcattactggaatgctttcgatatatggggccaagggacgatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9778 JY8QFUQ01C4MA5 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.16.38.11] CARQSVPYTEYFNWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaggggctggagtgggtggcaattatatggcatgatggaaccaataaatactatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacagtgtatctgcaaatgaatagcctgagagccgaggacacggctgtgtattattgtgcgagacagtctgtaccatataccgaatatttcaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +9779 JY8QFUQ01B3MG7 No results +9780 JY8QFUQ01CY8WM productive Homsap IGHV3-11*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9781 JY8QFUQ01CFBLX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKLGVAATTWNFFDYW in-frame + ctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9782 JY8QFUQ01BSMZD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame + ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9783 JY8QFUQ01AWS99 productive Homsap IGHV3-33*03 F 927 92.17 200/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9784 JY8QFUQ01AYWM5 No results +9785 JY8QFUQ01BOY6G productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9786 JY8QFUQ01CHNUD productive Homsap IGHV3-66*02 F 840 88.32 189/214 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-8*01 F 3 8 7 11 8.7.11 [1.17.38.11] CASHLMVYALDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccgtcagtggcaagtacatgagctgggtccgccaggctccagggcagggactggagtgggtctcagttatctatagtactggtagtacatactacgcagattccgtgaaagggcggttcaccatctccagagacagttccaacaacactctatatcttcaaatttacggcctgagagctgacgacacggctacttactactgtgcgagtcacttaatggtgtatgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9787 JY8QFUQ01AL15Q No results +9788 JY8QFUQ01CSGFJ No results +9789 JY8QFUQ01BAJWO productive (see comment) Homsap IGHV3-30*01 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaaggggActagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcaccctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcc +9790 JY8QFUQ01CZ1NI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARWDTSGWPFLDYW in-frame + ctctggattcacctttaacaattatgccatgacctgggtccgccaggctccagggaaggggctggagtggctctcatatattagtactagtggtggtaatacataccacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacttgctgtatctgcaaatgaataggctgagagtcgacgacacggccgtgtatttctgtgcgagatgggatactagtggctggcctttccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9791 JY8QFUQ01A7782 No results +9792 JY8QFUQ01BKODT productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 896 90.37 197/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [2.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) tgttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgGactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9793 JY8QFUQ01BUU4Q unknown (see comment) Homsap IGHV3-16*01 ORF 94 53.45 62/116 nt 8 X X 8.X.X [25.5.X.X] null + No rearrangement found ctctggattcacctttagtagttctgccatgaactggaggagtctgggggaggcttggttcagccgggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9794 JY8QFUQ01ASXS0 No results +9795 JY8QFUQ01AVQBY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9796 JY8QFUQ01CJW5Z No results +9797 JY8QFUQ01B475P productive (see comment) Homsap IGHV1-18*01 F 970 95.31 203/213 nt 94.84 202/213 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-3*01 F 1 7 8 20 7.8.20 [0.17.38.11] CARDHRSGALEWSHHYHGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) tggttacatcttcaccactatggtatcaactgggtgcgccaggcccctggacaagggcttgagtggatgggatggatcagcgcctacagtggtaacacaaagtatgcacagaaggtccagggcagagtcaccatgaccacagacacttccacgagtacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagatcacagaagcggggctttggagtggtctcaccactaccacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9798 JY8QFUQ01DPLAU productive (see comment) Homsap IGHV4-34*10 F 814 86.57 187/216 nt 85.65 185/216 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [2.17.38.11] CARNTNYGGNSGDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AA' (2 nucleotides at position 61 to 62 in the user submitted sequence), (cause frameshift); gtgtctggtgagtccttcactaattactactggagctggGatccgccagtcccccaggaaAAgggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9799 JY8QFUQ01BS1DJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 897 90.0 198/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARRTITAAGRGDDYW in-frame - ggcctctgaattcacctttagcagttttgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagcattggtactagtgttgttaacacatggtacgcagactcagtgaagggccggttcgccatttccagagacaattccaagagcacgctgtatttgcaaatgaatagcctgagagtcgaggacacggccgtatattactgtgcgaggaggacaataacagcagctggccgtggggatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggcgttcttccccca +9800 JY8QFUQ01DHGEG unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 394 86.54 90/104 nt 84.62 88/104 nt 8 8 X 8.8.X [1.16.1.X] null + No rearrangement found in FR2-IMGT at codon 51 of V-REGION: 'AG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 47 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggaggggcgtggAGagtgggtctcagccattagtggcagtggtagtcggacatatt +9801 JY8QFUQ01CJ8EZ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame - tctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctattcggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9802 JY8QFUQ01AZS42 productive (see comment) Homsap IGHV3-66*02 F 907 92.02 196/213 nt 90.61 193/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.16.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcagtagcagcttcatgacttggtccgccagctccaggaaaggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9803 JY8QFUQ01AECOG unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F (see comment) 222 59.39 98/165 nt 7 8 X 7.8.X [X.17.22.X] null - No rearrangement found Low V-REGION identity (59,39% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atacaccttcagcaactactatagacactgggtgcgacaggcccctggacaagggcttgagtggatgggaatgatcagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9804 JY8QFUQ01CW651 unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F (see comment) 617 75.69 165/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9805 JY8QFUQ01CWKRF productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9806 JY8QFUQ01CAVJ6 No results +9807 JY8QFUQ01CGXHA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 406 89.11 90/101 nt 8 7 X 8.7.X [1.17.X.X] null - No rearrangement found cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagggtgttgaca +9808 JY8QFUQ01CX0CA productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*03 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 7 16 8.7.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtacctattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcatatgatggaaaaaaaagtattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtacctgcaaatggacagcctgaggcctgaagacacggctgtatattactgtgccagagatgagctcccttgggatacaatagagtactactttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9809 JY8QFUQ01AVQ0D productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1011 97.2 208/214 nt 96.73 207/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagctactatttgcactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaaAgctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcgaggggacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9810 JY8QFUQ01DC50K productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKGLYYYDSSGYRVFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); ctctggattcacctttagcaactTttgccatgagctgggtccgccaggctccagggaagggactggagtgggtctcgactattagtcctagtggtggtaccacatattacgcagactccgtgaagggccggttcaccatctccagagacagttccaagaacacgctgtatctgcaaatgaacatcctgagagccgaggacacggccacatattactgtgcgaaaggactatattattatgacagtagtggttatcgggtctttgactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9811 JY8QFUQ01CRPMT productive (see comment) Homsap IGHV3-7*01 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ3*01 F (see comment) 151 78.0 39/50 nt Homsap IGHD3-16*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARATNADVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); cctctggattcacctttaGgggggtactggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaccataaatcacgatggaagtcaaatttactatatggaccttgtgaagggccggttcaccatctccagagacaacgccgagacctcactctatttgcaaatgaacaccctgagagccgaagacacggctgtctattactgtgcgagggcgactaatgccgacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9812 JY8QFUQ01DDSS5 No results +9813 JY8QFUQ01BOUSY No results +9814 JY8QFUQ01AODPS productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 733 82.41 178/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [2.17.38.11] CARDWGGSFDRYYFDYW in-frame - Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaagatcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9815 JY8QFUQ01C0UJ2 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CASRLRSSGGY## out-of-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) tctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9816 JY8QFUQ01CGLOU unproductive Homsap IGHV3-7*01 F 899 91.16 196/215 nt 90.7 195/215 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-3*02 F 1 8 8 X 8.8.X [1.16.38.11] CARGSYWHYDTFGDY# out-of-frame - in FR2-IMGT, from codon 44 of V-REGION: 2 nucleotides (from position 44 in the user submitted sequence), (cause frameshift) ctctggatttacttttaacaactattggatgacctgggtccgcagccccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattgggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9817 JY8QFUQ01CSNZ1 unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 930 92.99 199/214 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [0.17.38.11] CARHEG*QPLLLLWLL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggataacagccgttactactactttggctactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9818 JY8QFUQ01CFBQI productive (see comment) Homsap IGHV3-7*01 F 1040 97.71 213/218 nt 96.33 210/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [2.16.38.11] CXSSPYFYDSNGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 31 in the user submitted sequence), (cause frameshift) gcctctggattcaggtttagcatctattggtgagctgggtccgccaggctccagggaaGggggctggagtgggtggGccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtntgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9819 JY8QFUQ01BA3JA unproductive Homsap IGHV3-7*01 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKGGGNGDLDY## out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'GT' (2 nucleotides at position 11 to 12 in the user submitted sequence), (cause frameshift); gacctctggaGTtcaacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9820 JY8QFUQ01CGQ0G productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame - ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9821 JY8QFUQ01CM5G9 unproductive (see comment) Homsap IGHV4-61*01 F 947 92.31 204/221 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD6-6*01 F 2 10 7 X 10.7.X [1.17.38.11] CTRGAVHL*QPV# out-of-frame + stop codons tctctggtggctccatcagcggtagtactaactactggagctggattcggcagcccccagggaagggactggaattcattgggtatatctattccagtgggaggaccaactacaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccagttctccctgaggctggcgtctgtgaccgctgcggacacggccgtgtattactgtacgaggggggcagtacacttatgacagcccgtggggacaggggacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggggcttcttccccca +9822 JY8QFUQ01CZVCH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9823 JY8QFUQ01A5ZUC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + tctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9824 JY8QFUQ01CUETO productive (see comment) Homsap IGHV4-61*01 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagAcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9825 JY8QFUQ01BWRWC productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 91 of V-REGION: 'N' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift); ctctggattcagcttcagtacctataacatgaactGgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatNgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9826 JY8QFUQ01DI5NC No results +9827 JY8QFUQ01C9VWY No results +9828 JY8QFUQ01BPX9U productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 932 92.2 201/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) ggcctctggattcaccCtttggttattatggcatgactggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9829 JY8QFUQ01A3G8O productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccaaccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9830 JY8QFUQ01AH5V2 productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9831 JY8QFUQ01A6EQ2 unproductive Homsap IGHV3-66*02 F 916 92.49 197/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CSTPTYCRGGSCSQ#FDYW out-of-frame + tctggattcaccgtcagtaactaccacatgaggtgggtccgccaggctccagggaaggggctggagtgggtctcagttatttacagcggtggtagtacatattacatagactccgtgaagggccgattcaccatctcgagagacgattccgagaacacagtgtatcttcaaatgaagagcctgagagctgaggacacggctgtatattactgttcgacgcccacatattgtaggggcggtagctgttcccagattttgactattggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +9832 JY8QFUQ01B4U53 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9833 JY8QFUQ01AXBN3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgagacgn +9834 JY8QFUQ01DJ538 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 330 72.87 94/129 nt 8 8 X 8.8.X [2.17.8.X] null - No rearrangement found Low V-REGION identity (72,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcgtctttaacaactatgccatgggctgggtccgccaggctccagggaaggggttggagtgggtctcatctattagtactagtggtcatcgcctgcctggtccagggcttcttccccca +9835 JY8QFUQ01ADCX5 productive Homsap IGHV4-61*02 F 893 89.59 198/221 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARDPRVICSGGSCRSSAMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaacccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagaccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9836 JY8QFUQ01ABSIT unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 817 85.59 190/222 nt 85.14 189/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 X 10.7.X [2.17.38.11] CARRWASNGWSW#YFDYW out-of-frame - in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); gtctctggtgactccatcagtagtactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgagcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9837 JY8QFUQ01CXFX3 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD2-8*01 F 3 8 8 X 8.8.X [1.17.38.11] CSIRMLGTTGVDY## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcacctttagcagctatgccatggactgggtccgccaggctccagggaaggggctggagtgggtctcagatattactggtggtggtggtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagccgaggatacggccatatattactgttcaataaggatgctgggaactactggtgtggactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgctgcctggtccagggcttcttccccca +9838 JY8QFUQ01C2FQW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9839 JY8QFUQ01B7VGR productive (see comment) Homsap IGHV4-61*02 F 875 88.69 196/221 nt 88.24 195/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); tctctggtggccccatcagcagcagcacttactactggacttggatGccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9840 JY8QFUQ01BECVX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9841 JY8QFUQ01CGFEU unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag +9842 JY8QFUQ01AO2RA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 598 75.46 163/216 nt 75.0 162/216 nt 8 7 X 8.7.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (75,46% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) gcctctgggtttacctttagcaactttgccatggcttgggtccgccaggctccaagaaaggggctggagtgggtctcagctattgctcgtggcggtgacacacactaccgagactccgtgaagggccgattcaccatctccagagacaattctaagaacacactgattctgcagatgcgtggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9843 JY8QFUQ01CH6NP No results +9844 JY8QFUQ01B3VCX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - cctccgggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9845 JY8QFUQ01C92F8 productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt 93.78 211/225 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGNYYDSGGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctagcagcagtgttgTtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcgaataactatcaagccagacgcatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtatattactgtgcaagagggggtaattactatgatagtggtggtcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtctngcctgcctggtccagggcttcttccccca +9846 JY8QFUQ01BPEL9 productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVKGAGTTVNWFDIW in-frame - cctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9847 JY8QFUQ01BEQRC unknown (see comment) Homsap IGHV3-72*01 F 921 90.58 202/223 nt 90.13 201/223 nt 8 10 X 8.10.X [1.17.38.X] null + No rearrangement found in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggtttccCccttcagtgaccacttcatggactgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctggggccaggggtacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +9848 JY8QFUQ01DQDNF productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + ctctggattcacctttagtgactattggatgaggtggttccgccagcctccaggaagggggctggagtgggtggccagcataaaagaagatggaagtgagaaaggttatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +9849 JY8QFUQ01CC0U5 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 857 87.78 194/221 nt 86.88 192/221 nt Homsap IGHJ3*01 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-16*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARTYTYRNAFDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'CCTG' (4 nucleotides at position 15 to 18 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); tctcgggtgactccCCTGagtgccagtagtagttTtctactggggctgggtccgccagcccccagggaagggactggagtggattgggactgtttattatagtgggagcgcccactacaatccgtccctcaagagtcgagtcgccatatccgtggacacggcccagaaccaggtctccctgacgttgaactctgtgaccgccgcagacgccgctgtctatttctgtgcgagaacttatacttatagaaatgcttttgacgtctggggccaggggacattggtcgctgtgtcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9850 JY8QFUQ01AN9JJ No results +9851 JY8QFUQ01CP9PQ No results +9852 JY8QFUQ01A9BQ0 unproductive Homsap IGHV3-7*03 F 932 92.2 201/218 nt 90.83 198/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARRRDYGDYGDGFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 50 of V-REGION: 'TGG' (3 nucleotides at position 65 to 67 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); cctctggatttagctttagaaccttttggatgagctgggtccgccaggctccaggggaggggcgTGGagagtgggtggccaaTcataaagtcagatgGgaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9853 JY8QFUQ01BIQFD productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.37.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 194 in the user submitted sequence), (cause frameshift) ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggcccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9854 JY8QFUQ01DFYTQ No results +9855 JY8QFUQ01B3OLZ productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9856 JY8QFUQ01CR5OE productive (see comment) Homsap IGHV3-7*01 F (see comment) 687 80.37 172/214 nt 79.44 170/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [0.17.37.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 51 of V-REGION: 'A' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccgAgtggtgggtgccaacatatccccagacggaaatacgaaatatttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9857 JY8QFUQ01DHUBM productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 7 12 8.7.12 [2.17.38.11] CARGTMIPRSFDNW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'TG' (2 nucleotides at position 76 to 77 in the user submitted sequence), (cause frameshift); gtctttggtgggtccttcagtggttactactggagctggatccgccagtccccagggaaggggctggagtggattTGgggcaaatcaatcatagtggagacaccagctataatccgtccctcaagagtcgagtcaccatttcaatagacaagtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacacggctgtgtattactgtgcgagaggcacaatgataccgagaagttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9858 JY8QFUQ01CYD71 No results +9859 JY8QFUQ01B9ZFO No results +9860 JY8QFUQ01BD2HK No results +9861 JY8QFUQ01AUBMD productive Homsap IGHV1-18*01 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt 8 8 8 8.8.8 [0.17.38.11] CARGDYFDHW in-frame + tggttacacctttaccagctatggtctcagctgggtgcgacaggcccctggccaagggcttgagtggatgggatggatcttcgtttttaacggtaacacaaaatatgcacagcacctccagggcagagtcaccatgaccacagacacatccacggacacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagaggtgactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcagatgggaacgtggtcatccgcctgcctggtccagggcttcttccccca +9862 JY8QFUQ01CB55E No results +9863 JY8QFUQ01DWET8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9864 JY8QFUQ01B6JVQ productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaaggggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9865 JY8QFUQ01C5YIK productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +9866 JY8QFUQ01DVH46 No results +9867 JY8QFUQ01AEOI2 productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +9868 JY8QFUQ01AWYUH No results +9869 JY8QFUQ01CXCAE productive Homsap IGHV3-66*02 F 863 89.3 192/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 12 8.7.12 [1.17.38.11] CARQTAPFGYFEDW in-frame - cctcggaattctccgtcagtgacagtcacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtagtgcatattatgcagactccgtgaggggccgattcaccatcgccagagacaaatctaagaacgtgttgtatcttcaaatgaacagtctgagacctgaggacacggctgtgtactactgtgcgagacagactgccccttttgggtactttgaggactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9870 JY8QFUQ01CY86E No results +9871 JY8QFUQ01B69EI No results +9872 JY8QFUQ01BM9NP productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 97 of V-REGION: 'T' (1 nucleotides at position 196 to 196 in the user submitted sequence), (cause frameshift); ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccTggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9873 JY8QFUQ01AEKQ9 productive Homsap IGHV3-74*03 F 811 87.62 184/210 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 7 8 13 7.8.13 [X.17.38.11] CVRDSDSSASYFAHW in-frame + ttcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +9874 JY8QFUQ01BD2XN No results +9875 JY8QFUQ01CJOO9 unknown (see comment) Homsap IGHV3-16*01 ORF, or Homsap IGHV3-16*02 ORF or Homsap IGHV3-19*01 P or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-35*01 ORF or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 139 88.57 31/35 nt 8 X X 8.X.X [1.2.X.X] null - No rearrangement found ctctggattcaccttcagcaaccataacatgaact +9876 JY8QFUQ01CQZGU productive Homsap IGHV1-8*01 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 12 8.8.12 [0.17.38.11] CARGRGYGSYADHW in-frame + tggatacagcttcagcaattatgatatcaactgggtgcggcaggccactggacaagggcttcagtggatggggtggatgaacccccacagtgccaatatcgtctacgcgcagaaatttcagggcagagtcaccatgaccagtgacgcctccataaccacagcctacatggaactgagcaacctgaaatctgacgacacggccgtgtattattgtgcgaggggccgagggtacggaagttacgctgaccactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9877 JY8QFUQ01CLTE0 productive (see comment) Homsap IGHV3-11*01 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARGYSYGCFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'GGAGGGACT' (9 nucleotides at position 89 to 97 in the user submitted sequence), (do not cause frameshift); ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcaaacatcaatagtGGAGGGACTagtgggaggaccatatattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagaggatacagctatggctgctttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +9878 JY8QFUQ01BKHHV productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1009 98.1 206/210 nt 97.14 204/210 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-17*01 F 2 7 8 16 7.8.16 [X.17.38.11] CARQLDYGDYSRHGLDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); cacaactttaccggctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatGggggatcatctatcctggtgactctgataCccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccgtgtattactgtgcgagacaattagactacggtgactactctaggcacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9879 JY8QFUQ01B1F8H No results +9880 JY8QFUQ01AKGC4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9881 JY8QFUQ01AV7KG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.16.38.11] CAKDQSCIVGPC#FDYW out-of-frame - in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttGatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggtttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9882 JY8QFUQ01C2MXP unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt 92.79 206/222 nt 8 7 X 8.7.X [4.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaagggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +9883 JY8QFUQ01CUDAI unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CAREKGSGPPHRHGRL# out-of-frame - Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcggggcccccccacaggcatggacgtctgggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9884 JY8QFUQ01A9NLW unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 873 89.4 194/217 nt Homsap IGHJ6*02 F (see comment) 94 61.29 38/62 nt Homsap IGHD2-8*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRPLREFDC## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccctctccagctatgctatgcactgggtccgccagtctcccggcaaggggctagagtgggtggcagctatttcatatgatggaagtaaaatatattacgcagactccgtgaggggccgcttctccatctccagagacagttccaagaacactctgcatttgcaaatggacagcctgagacctgaggacacggctacatattactgtgcgagagatagacggccacttagggagtttgactgttggggtccagggaaccccggtcgccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctcggtccagggcttc +9885 JY8QFUQ01BJJ76 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - tctccggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9886 JY8QFUQ01C34Y1 No results +9887 JY8QFUQ01ANHIG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + tctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9888 JY8QFUQ01DJ4YH productive (see comment) Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 385 89.58 86/96 nt 88.54 85/96 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD5-18*01 F 3 X X 15 X.X.15 [X.X.32.11] CARSDEEYSYGDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'ACTAT' (5 nucleotides at position 23 to 27 in the user submitted sequence), (cause frameshift); gcgtctggattcaccttcagtaACTATgagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatcggacgaggaatacagctatggggatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9889 JY8QFUQ01ANG49 productive (see comment) Homsap IGHV3-66*02 F 903 91.59 196/214 nt 91.12 195/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctCcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9890 JY8QFUQ01B3AFP productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1011 95.07 212/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcacccgttaaaggcagattcaccatctcaagagaggattcaaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctccttcaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9891 JY8QFUQ01BC5ZQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 980 95.35 205/215 nt 94.88 204/215 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.16.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) tctggattcacctacagcagctatgccatgagctggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaaggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9892 JY8QFUQ01ALBF8 No results +9893 JY8QFUQ01ANMRQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 784 84.47 185/219 nt 83.56 183/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); tgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcgggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9894 JY8QFUQ01CQEH2 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccgaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9895 JY8QFUQ01COGUP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9896 JY8QFUQ01A8J17 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1039 98.15 212/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [2.17.38.11] CASANYDYVWGELSL#DYW out-of-frame - stop codons tctcctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9897 JY8QFUQ01CRDMB No results +9898 JY8QFUQ01CUFLZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame + cctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc +9899 JY8QFUQ01B8O1A productive Homsap IGHV3-33*04 F (see comment) 698 80.28 175/218 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame - Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release catttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9900 JY8QFUQ01C0EU8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - cctctggattctccgtcagtaattactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9901 JY8QFUQ01AX7BT productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.38.11] CARGRTVVTVIDYIDYW in-frame + tctctggggactccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9902 JY8QFUQ01AQBBV unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*02 F or Homsap IGHV3-33*03 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F or Homsap IGHV3-64*01 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 115 54.2 71/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons gtctggattcaccttcagtagctacggcatgcactgggtccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +9903 JY8QFUQ01ARPT2 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 7 12 8.7.12 [1.17.38.11] CARAPGWMNPFDF* in-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctccggtggcaccatcaccagttactacgtgagctggctccggcagcCccccagggaagggactggagtggattgggtgtatctcttatagtgggagcactacctacaactcctccctcaagagtcgagtcaccatatcaggagaagggtccacgcgccagttctccctgaggctgagctctgtgaccgttgcggacacggccgtgtattactgtgcgcgagccccaggatggatgaatccctttgacttctagggccagggcactctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9904 JY8QFUQ01AO4GF unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [1.17.38.11] CARGSYWHYDTFGDY#W out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagggtcgtattggcattatgataccttcggcgactatttggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag +9905 JY8QFUQ01CAFC1 productive Homsap IGHV3-72*01 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame + cctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9906 JY8QFUQ01CC682 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWGELSL#DYW out-of-frame - stop codons ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9907 JY8QFUQ01A7S16 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1009 98.1 206/210 nt 96.67 203/210 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-17*01 F 2 7 8 16 7.8.16 [X.17.38.11] CARQLDYGDYSRHGLDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); cacaactttaccggctactggatcggctgggtgcgccagatgcccgggCaaaggcctggagtggatGggggatcatctatcctggtgactctgataCccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccgtgtattactgtgcgagacaattagactacggtgactactctaggcacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9908 JY8QFUQ01BH7IB productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDIGGRYSYW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgcaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9909 JY8QFUQ01B2OZJ No results +9910 JY8QFUQ01DDP29 No results +9911 JY8QFUQ01CDP4D productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAREGGRGSSSEDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'TC' (2 nucleotides at position 12 to 13 in the user submitted sequence), (cause frameshift); gcctctggattTCagccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaatggtgcttacatatactacgcagactcaatggagggccgattcaccatctccagagacaacgccaggaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgcgagagggggggcggggcagttcgtcggaagactactttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9912 JY8QFUQ01BMULJ productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 894 91.12 195/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-18*01 F 1 8 8 15 8.8.15 [0.17.38.11] CAIVDTNLVSATGKDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacaccttcagcaactactatagacactgggtgcgacaggcccctggacaagggcttgagtggatgggaatgatcaaccctagtagtgattacaaatattacgcacagaaatttcagggcagagtcaccatgaccagggacacgtccacgagcacagtcttcatggagctgagtagcctgagatctgacgacacggccgtgtattattgtgcaatagtggacacaaatttggtttcggcgaccggtaaagactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9913 JY8QFUQ01BY0XS productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9914 JY8QFUQ01BQXPO productive Homsap IGHV3-30-3*01 F, or Homsap IGHV3-30-3*02 F (see comment) 403 78.79 104/132 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 X 6 18 X.6.18 [X.X.38.11] CARDDFYSSGNYGGFGMDVW in-frame - Low V-REGION identity (78,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcaccttcagtcactatgactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +9915 JY8QFUQ01AHRBA productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 691 80.75 172/213 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [1.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame + Low V-REGION identity (80,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9916 JY8QFUQ01BF9YK productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1002 96.73 207/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARTTSSSGWYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); ctctggaggctccattagtaattactacCtggagttgGgatccggcagcCccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaatcagttcttcctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgaggactacttctagtagtggctggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9917 JY8QFUQ01C61BA productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 998 96.28 207/215 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD1-26*01 F 1 8 7 18 8.7.18 [1.17.38.11] CARGWAQQAGATFVGWFDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tctatggtgggtccttcagtggttacacctggaactggatccgccagcccccagggaaggggctggagtggattggggaaatcaatcatagtggcaggaccaactacaacccgtccctcaagagtcgagtcaccatatcaatagacacgtccaacaaccagttctccctgaagctgagctctgtgaccgccgcggacacggctgtgtatttctgtgcgagaggttgggcccaacaagcgggagctacgtttgttggctggttcgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccc +9918 JY8QFUQ01BXWLQ productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcacctttgatgattttggcatgagatgggtccgccaagtcccagggaaggggctacagtgggtctctgggattaattggaatggtgctaaaacaggttatgcagcctctgtgcagggccgattcaccatctccagagacaacgacaacaacgtcctgtatctgcaaatgaacagtttgagacccgaggacacggccttgtatcgctgtgcgagagaggtttcggacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9919 JY8QFUQ01B1949 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9920 JY8QFUQ01BTDOA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagg +9921 JY8QFUQ01BP7OM productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 908 91.63 197/215 nt 90.7 195/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 7 8 10 7.8.10 [1.16.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) ctctggattcagcttaagttctatggcatgaactgggtccgccaagctccagggaaggggctgtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9922 JY8QFUQ01AH3ST productive (see comment) Homsap IGHV1-18*01 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-22*01 F 3 8 8 18 8.8.18 [0.17.38.11] CARTPRIVVVPSADYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggttacatctttagtagttatggtctcaggtgggtgcgacaggCcccctggacaagggcttgagtggatgggatggatcagcgtttacagtggtaacgcaaattatgcacagaagttccagggcagagtcaccatgaccacagacagatccacgaccacagcctacatggaactgaggggcctgagatctgacgacacggccgtgtattactgtgcgagaacccctaggatagtagtggtcccctccgcagactacggtatggacgtctggggccaagggaccacggtccgcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcancgcctgcctggtcagggcttcttcccc +9923 JY8QFUQ01CBDCA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGG# out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctgggttcaAtttttggccactataccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9924 JY8QFUQ01BOI5P No results +9925 JY8QFUQ01C7H6S productive Homsap IGHV4-39*02 F 947 91.86 203/221 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [1.17.38.11] CARRYSWNYERFDPW in-frame + tctctggtgactccatcagtactaataattactactgggcctggatccgccagcccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9926 JY8QFUQ01A14EE productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 815 86.24 188/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame + cctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +9927 JY8QFUQ01CJW2Z productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt 88.37 190/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtacttactactggacatgGgatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaaGgccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9928 JY8QFUQ01BLRMD productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F 330 88.24 75/85 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 X X 10 X.X.10 [X.X.28.11] CARLGQLALDYW in-frame + caccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgcctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +9929 JY8QFUQ01A7KOE productive (see comment) Homsap IGHV3-48*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGRAASGTSFDNW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtacctatgccatgaactgggtccgccaggctccagggaaggggctggaatggAttttcatacattagtactagtagtatacccatatactacgcagactctgtgaagggccgattcaccgcctccagagacgatgccaagaactcgctgtatctgcaaatgaacggcctgagagacgaggacacggctatgtattactgtgcgagaggcagagcagcatctggtacttcttttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9930 JY8QFUQ01A5ZSM No results +9931 JY8QFUQ01A52AK unknown (see comment) Homsap IGHV4-61*02 F (see comment) 270 58.06 126/217 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (58,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtgggggtgtcgactacaacccctcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +9932 JY8QFUQ01AHHQ3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9933 JY8QFUQ01AO4OI No results +9934 JY8QFUQ01CZNG1 unproductive (see comment) Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDSVPRVVRGC#YHFDYW out-of-frame + stop codons ctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggtcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +9935 JY8QFUQ01CKI1Y productive Homsap IGHV1-2*02 F 1029 98.13 210/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-3*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARAIDFGSGDKRGFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacaccttcaccggctactctatacactgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcaaccctaacagtggtggcacaaactatgcacagaaatttcagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggagctgagcaggctgacatctgacgacacggccgtgtattactgtgcgagagccatcgattttgggagtggtgacaaacgggggtttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9936 JY8QFUQ01DJE0A No results +9937 JY8QFUQ01B2LWA unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F (see comment) 639 76.96 167/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (76,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctcgggattcaacttcaagtccaacaccatgaattgggtccgccaggctccagggaaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9938 JY8QFUQ01B1WL0 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 863 89.3 192/215 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame + cctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggcaacgtggtcatcgcctgcctggtccagggcttcttccccc +9939 JY8QFUQ01AHCGW productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 830 90.15 183/203 nt 89.66 182/203 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-10*01 F 3 5 7 21 5.7.21 [X.17.38.11] CARLTPLTMVPGTHYYYHSMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'CACAACCCCTCCCTCCTG' (18 nucleotides at position 111 to 128 in the user submitted sequence), (do not cause frameshift); ccatgactggttactactggagttggatccggcggcccccaggtaagggactggagtggattggctatatctactacaccgggtacaacaactacaacccctccctcatcCACAACCCCTCCCTCCTGagtcgactcaccatatcagtcgacacgtccaagaaccagttctctctgacgctgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagattgacacccctgactatggttccgggaactcactactattaccacagtatggacgtctggggccaagggaccgcggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9940 JY8QFUQ01AWZXQ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [2.17.38.11] CTREVGATDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctccggattcaCcctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9941 JY8QFUQ01A6YG1 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F (see comment) 645 75.98 174/229 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 8 10 8.8.10 [5.17.38.11] CGTFGGTHFDDW in-frame + Low V-REGION identity (75,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release aaccggaatcagattcggaagcaaattcggcaatgcctgggtcggttgggtgcgccagaagcccgggaaaggcctggagtggatgggaatcattcatccgagtgactctgaggctagatatggtccgtccttcaaaggccaggtcaccttctcggtcgacaagtccaccgatatcgcctacttgaattgggaccgcctggcggcctcggacaccgccacatattattgtggtacctttggtgggacccactttgacgactggggccagggaactgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9942 JY8QFUQ01BSU4G unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*06 F (see comment) 476 68.84 148/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found stop codons Low V-REGION identity (68,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctatggtgggtccttcagtggttactattggagctggatccgccagcccccagggaaggggctggagtggattggggaaatcaatcatagtggaggcaccaactacaacccgtccctcaagagtcacggaagaattgtattactaccagctgctatgagagggatttgactactggggcccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgcctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactcag +9943 JY8QFUQ01DTFU3 productive (see comment) Homsap IGHV3-66*03 F (see comment) 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 3 8 8 16 8.8.16 [2.17.38.11] CVKDMQGVGDIAIGFDYW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01DTFU3 ; 7 AA in Homsap_IGHV3-66*03) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 98 of V-REGION: 'A' (1 nucleotides at position 199 to 199 in the user submitted sequence), (cause frameshift); gcctctgggttcaccgtcagtagcaagttcatgagctgggtccgccagggtccagggaaggggctggagtgggtctcaggtattagtgctcgtggtagtagtgcgtactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactgtatctgcagatgaacagcctgagacctgaaAgacacggctttgtattactgtgtaaaagatatgcaaggagtcggggacatagcgattggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9944 JY8QFUQ01CSJ9L No results +9945 JY8QFUQ01COQVX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 828 87.1 189/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARLRSFGDYPLDVW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +9946 JY8QFUQ01DM14N unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.37.11] CMNEFGYCSGG# out-of-frame - in FR3-IMGT, from codon 89 of V-REGION: 1 nucleotides (from position 171 in the user submitted sequence), (cause frameshift) gctctggattcacttttagcagccatatgatgacttgggtccgccaggctccagggaaggggctggaatgggtcgcaagtattcgtgccagtggtggtaggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgttgtattgcaaatgtacagtctgagagtcgaggacacggccttatattattgtatgaacgaattcggatactgtagtggtgggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9947 JY8QFUQ01B5CJQ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1017 96.77 210/217 nt 96.31 209/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 11 8.8.11 [2.16.38.11] CVVQILGATIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcaatacctatagcatgaactgggtccgccaggctccaggaagggctggagtgggtctcatccattagtagtggtagtacttacataaagtacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtggtccagatcctaggggctacgattgactactggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9948 JY8QFUQ01DQMOY unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 940 93.06 201/216 nt 91.67 198/216 nt Homsap IGHJ1*01 F (see comment) 116 69.23 36/52 nt Homsap IGHD3-10*01 F 1 7 8 X 7.8.X [2.16.37.11] CARDMGSGRYFEPYDY# out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) gcctctggattcacctttagtagtttgccatgacctgggtccgtcaggctccagggaagggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgagggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagatatgggttcgggaagatactttgaaccttatgactactgggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9949 JY8QFUQ01CII48 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 823 87.04 188/216 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGFSAWGQDAFDIW in-frame - tctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctctaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9950 JY8QFUQ01AJ990 No results +9951 JY8QFUQ01C7E6O No results +9952 JY8QFUQ01CL6TY No results +9953 JY8QFUQ01DUSC7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 829 86.76 190/219 nt 86.3 189/219 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD5-18*01 F 2 8 8 16 8.8.16 [2.17.38.11] CVKDWGPNRQMWFGESLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'GCTGTTGCC' (9 nucleotides at position 94 to 102 in the user submitted sequence), (do not cause frameshift); gcctctggattcacgttcagcagctatgccatgacctgggtccgccagactccagggaaggggctggagtgggtctcaactattcatggcggtGCTGTTGCCggtggcaccacagactacgcggtctccgcccagggtcgattcaccatctccagagacaattccaagagcacactgtatttgcaaatgagcgacctgagacccgaggacacggccctctatttctgtgtgaaagactggggccccaatcggcagatgtggttcggggagagtctctggggccagggaactctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9954 JY8QFUQ01CF976 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame + ctctggattcacctttagtaactcttggatgagttgggtccgccaggcaccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +9955 JY8QFUQ01ALN7I productive Homsap IGHV4-61*03 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 10 7 12 10.7.12 [1.17.38.11] CTRHPKSNVEGDSW in-frame + ccctggtggctccgtcagcagtggtagttatttctggagctggatccggcagcccccagggcaggggctggaatggatcggttatgtctataacaatgggaacaccaattacaacccttccctcaagagtcgagtcaccatttctatagacacgtccgagaatcacgtctccctgaagctggcctctgtgaccgctgcggacacggccgtgtactactgtacgaggcacccgaagtctaatgtagagggtgactcctggggccagggagccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9956 JY8QFUQ01ALA6P No results +9957 JY8QFUQ01CTAB8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1026 97.24 211/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 11 8.8.11 [1.17.38.11] CVVQILGATIDYW in-frame + ctctggattcaccttcaatacctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtggtagtacttacataaagtacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtggtccagatcctaggggctacgattgactactggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +9958 JY8QFUQ01C52U4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 784 84.47 185/219 nt 84.02 184/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); tgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9959 JY8QFUQ01C4FA2 No results +9960 JY8QFUQ01CF6ST productive Homsap IGHV3-7*01 F 828 87.1 189/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CGRDERGADLPNDSW in-frame - Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccgttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagccccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctggggcctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9961 JY8QFUQ01AXLC8 No results +9962 JY8QFUQ01BR9Q4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKRWRASNGHFDYW in-frame + ctctggattcacctttagcagcttttccatggggtgggtccgccaggctccagggcggggactggagtgggtctcagccattgacggtcttactggtggtacatattacgcggactccgtgaggggccgattcaccatctccagagacgattccaagaacacactgtatctgcaaatgaatagcctgagagccgaggacacagccatatatcactgtgcgaagcggtggcgtgcttccaatggccactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +9963 JY8QFUQ01AX25U No results +9964 JY8QFUQ01DXDJW productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 938 91.86 203/221 nt 90.95 201/221 nt Homsap IGHJ6*02 F (see comment) 205 83.05 49/59 nt Homsap IGHD5-24*01 ORF 3 8 8 11 8.8.11 [2.17.38.11] CARPRYGYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift); ggggttctggatacgactttaacaactactgGgatcggctGgggtgcgccagatgcccgggaaaggcctggagtggatgggaatcatctttcctggtgactctgatatcagatatagtccgtcgttccaaggccaggtcaccatctcagtcgacaagtccatcggcaccgcctacctgcaatggagcggcctgaaggcctcggacaccgccacttattattgtgcgagacctagatacggatacggcttggacgtctggggccaagggaccacggtcaccgtctcctcagcccccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9965 JY8QFUQ01CIRGT unproductive Homsap IGHV3-11*01 F (see comment) 963 94.01 204/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] YARRRDYGDYGDGFDY## out-of-frame + Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactatgcgagacggcgggactacggtgactacggtgacggctttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +9966 JY8QFUQ01A1JOY No results +9967 JY8QFUQ01BD8XY productive (see comment) Homsap IGHV3-11*01 F 792 85.25 185/217 nt 84.79 184/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 3 7 8 16 7.8.16 [1.17.38.11] CVRDGARRTNQWLAHDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) cctctggattcagctttatgccttctatatgggttgggtccgccaggctccaggaaaggggctggagtggatttcgtacattaactctggtggtagtgacacatattacgcagactctgtgaagggccgattcaccatctccagggacaacgcctgggacacaatgtacttggaaatgaacagcctgagagccgaagacacggccgtctactattgtgtgagagatggcgctagaaggacgaatcagtggctggcccatgacttctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9968 JY8QFUQ01DFFYM No results +9969 JY8QFUQ01DN8E2 No results +9970 JY8QFUQ01DCNR9 No results +9971 JY8QFUQ01BXLK3 No results +9972 JY8QFUQ01CNJCD productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +9973 JY8QFUQ01DTGIL productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.16.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtacatactggatgcactgggtccgccaagtccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9974 JY8QFUQ01C68VA unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD2-8*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDRGLY*WCMLCRRLL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggtttgtactaatggtgcatgctatgtcgccgacttctggggcccagggaacccaggtcaccgtctcctcagcctccaccaaggggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9975 JY8QFUQ01BQIY5 No results +9976 JY8QFUQ01AU2EL unknown (see comment) Homsap IGHV3-66*02 F 753 92.53 161/174 nt 8 7 X 8.7.X [4.17.21.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgta +9977 JY8QFUQ01C52KT productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9978 JY8QFUQ01BP884 unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 932 92.2 201/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaaggggaccacggtcaccggtctcctcagcctccacccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9979 JY8QFUQ01CLGUE unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLPFIVVVTGAFLGHFDY## out-of-frame + ttctggatacatctttaccaattactggctcggctgggtgcgccagatgcccggcaaaggcctggagtggatggggatcatctttcctgctgactctgatgcccgatacagcccgtccttccaaggccaggtcaccatctcaatcgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacgccgccatatattactgtgcgagactcccctttattgtggtggtgactggtgcgtttttgggacactttgactattggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9980 JY8QFUQ01DOXWU unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 804 86.45 185/214 nt 84.58 181/214 nt Homsap IGHJ1*01 F 80 61.54 32/52 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARRWARQRLVMDYFDYW# out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'ACTATTG' (7 nucleotides at position 31 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'T' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); ctctggtggActccatcagtagtgactcatACTATTGggggctggatccggcaGgcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaacTgggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactgggggccaggggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9981 JY8QFUQ01CN374 No results +9982 JY8QFUQ01AXNOE productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9983 JY8QFUQ01ASS6V productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9984 JY8QFUQ01C3PTZ productive Homsap IGHV4-59*03 F (see comment) 728 82.33 177/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [1.17.38.11] CARHEGSYYDTAGYSDAFDIW in-frame + Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggcgtctccatcaccgattacttctggagttggatccggcagtccccaggagggcgactggagtggatctcatatatctatcacactgggaccaccaagtccaacccctccctcaagagccgagtcaacatgtcactggacaggtccaagaaccaattttccctgagcttgaagtccgtaaccgcagcggacacggccgtctattactgtgcgagacacgagggaagttactatgatacggctggttattcggatgcttttgatatctggggccaagggacaatggtcaccgtctcttcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgggtccagggcttcttccccca +9985 JY8QFUQ01BFXV9 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9986 JY8QFUQ01CHGAZ No results +9987 JY8QFUQ01DD9NX unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 992 96.24 205/213 nt 95.77 204/213 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 73 60.42 29/48 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [0.17.37.11] CARGTAASRLLXL# out-of-frame - in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 211 in the user submitted sequence), (cause frameshift) tggatacaccttcaccagctactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagntacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattatgtgcgagggggacagcagcttcgagacttttantactggggccaggggaaccctggtcaccgtccccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9988 JY8QFUQ01A6B1B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDREDSSGYYFFRDGFDIW in-frame - ctctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctccggtattggtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagatcgtgaagatagtagtggttattacttcttccgtgatggttttgatatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9989 JY8QFUQ01BGWR7 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CAEKKVRAPH#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcagagaaaaaggttcgggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9990 JY8QFUQ01DWB0T productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +9991 JY8QFUQ01AQ0QS unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 946 92.69 203/219 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-20*01 F 3 8 8 X 8.8.X [2.17.38.11] CAARIDSVITG#AFDIW out-of-frame - ggctctggatacagtttcaccaactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctggtgactctgatacccggtacaacccgtccttccaaggccaggtcaccttctccgtcgacaagtccatcaacaccgcctacctgcagtgggacagcctgaagacctcggacaccgccaagtattactgtgcggcgagaattgatagtgtcattactggaatgctttcgatatatggggccaagggacgatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +9992 JY8QFUQ01CI01U unproductive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDY* in-frame + stop codons in FR3-IMGT at codon 74 of V-REGION: 'A' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); ctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtgggctctgtgatggAgccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactgaggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttcccccag +9993 JY8QFUQ01C05SU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9994 JY8QFUQ01C0IGV productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 750 83.64 179/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +9995 JY8QFUQ01BEL27 No results +9996 JY8QFUQ01ASN9O productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcggcagttataggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +9997 JY8QFUQ01APBJY productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +9998 JY8QFUQ01DQFEE productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 662 77.98 170/218 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIVREGLDHW in-frame + Low V-REGION identity (77,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tgtctggtggctccatcgccacttatcattggtggaattgggtccgccagacccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +9999 JY8QFUQ01C6CH8 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 923 91.74 200/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [2.17.37.11] CTKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 127 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagatactggGatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaaggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10000 JY8QFUQ01BRFFP productive Homsap IGHV1-69*06 F, or Homsap IGHV1-69*10 F or Homsap IGHV1-69*14 F 885 90.65 194/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [0.17.38.11] CAREQFYYNSGTYHHYHMDVW in-frame - tggagacacattcaccagctatgctatcagctgggtgcgacaggcccctgggacaaggcttcagtggatgggagggatcatccccagatatggtatatcacactacgcacagaagttccagggcagagtcacgattaccgcggacagatccacgagcacagcctacatggagctgaccagcctgacgtctgaggacacggccctgtattactgtgcgagagaacaattttactataatagtgggacttatcaccattaccatatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10001 JY8QFUQ01CIJSW productive Homsap IGHV4-61*02 F (see comment) 776 83.71 185/221 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERGTAVGGARELDSW in-frame + Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tgtctggtggccccgtcagcagtgatggttactactggacctggatccgccagcccgccgggcagggactggagtgggtcggacgtgtttccagtcgtggggagaccgactacagttcctccctcaagagccgaatcaccatgtcaatagacacgtctaagaaccagttctccctgaggttgaactctgtgaccgccgcagacacggccctatactactgtgcgagagagcgcggtactgcggttggcggagcgagagaacttgactcctggggccagggatcccaggtcaccgtctcgtcagcatcccccgaccagccccaaggtnttccccgtgagctctcgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10002 JY8QFUQ01AEMV4 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10003 JY8QFUQ01B82OW productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.02 200/215 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10004 JY8QFUQ01AX7NA No results +10005 JY8QFUQ01BBF1T productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYG in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaGggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactacgggggccagggaaccctggtcaccgtctcctccgcatcccctgaccagccccaaggtcttcccgctgagcctcctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +10006 JY8QFUQ01A55GJ unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 131 52.11 99/190 nt 8 8 X 8.8.X [1.17.30.X] null - No rearrangement found stop codons tctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10007 JY8QFUQ01BODQ3 unknown (see comment) Homsap IGHV5-51*05 F 149 56.62 77/136 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found gttctgcatatagtttttccagttactggatcgcctgggtgcgccagatgcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10008 JY8QFUQ01BU0QK No results +10009 JY8QFUQ01AVC9I No results +10010 JY8QFUQ01CNO7Z productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); gcctctggaGttcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10011 JY8QFUQ01CKARQ No results +10012 JY8QFUQ01AF2VS No results +10013 JY8QFUQ01AJ3KH productive Homsap IGHV1-2*02 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDWGGTYAPLDNW in-frame - tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaaccttgaccagtgacacgtccatcagtacagcctacatggaaatgagcgggctgacgtctgaggacacggccatcttttactgtgcgagagattggggtggcacgtacgctccgcttgacaattggagccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10014 JY8QFUQ01BGWHY No results +10015 JY8QFUQ01DP1AC productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 632 76.47 169/221 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD3-10*01 F 3 10 7 20 10.7.20 [1.17.38.11] CATSTTRVRGAIRNLVTWFDPW in-frame + Low V-REGION identity (76,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgggtgtctccacaaccagtcaatttaacttctgggtctggatccgccagcctccagggaaggcaccggagtggatagccagttcacgttatggagggaagacgttttacaatccgtcgctcgagagtcgggtcaacatgtctctgagcacgtctaagaatcagttttacctgaacctgatgtctgtgaccgccgcagacacggctgtttatttctgtgcgacgagcaccactcgagttcggggagccatcaggaaccttgttacctggttcgacccctggggcccgggaactcgagtgactgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10016 JY8QFUQ01C380Y unproductive (see comment) Homsap IGHV3-9*01 F 445 90.74 98/108 nt 89.81 97/108 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 X 16 8.X.16 [1.15.11.11] CAKDGSAIPVTGTYFEYW in-frame - stop codons in FR2-IMGT, from codon 54 of V-REGION: 109 nucleotides (from position 75 in the user submitted sequence), (cause frameshift) ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggaatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10017 JY8QFUQ01DJCM2 No results +10018 JY8QFUQ01AG17U unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDNYGDYW# out-of-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10019 JY8QFUQ01CD9A5 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10020 JY8QFUQ01ABZPQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10021 JY8QFUQ01BMW48 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.37.11] CARGLAVILGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 157 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10022 JY8QFUQ01BT8I3 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 3 8 8 X 8.8.X [1.17.37.11] CAKGQFGTVMDY# out-of-frame + in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 207 in the user submitted sequence), (cause frameshift) tctggattcacctttaacgactatggcatgacttgggtccgccaggctccagggatggggctgcagtgggtcgcaaccattagtggaagtggcgacagaacattctacgcagactccgtgaagggccgcttcatcgtttccagagacaactccaagaacacgctgtatctgcaaattaccagcccgagagccgaggacacggccgtttttattgtgcgaaaggccagtttggtaccgtcatggactattgggccagggaacccaggtcgtcgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10023 JY8QFUQ01C7FQ1 No results +10024 JY8QFUQ01B4PYG unproductive (see comment) Homsap IGHV3-7*01 F 848 87.33 193/221 nt 85.52 189/221 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [2.17.38.11] CARGDEFLEW*T#FDPW out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 41 of V-REGION: 'CT' (2 nucleotides at position 39 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GAA' (3 nucleotides at position 62 to 64 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); cctctggagttcagtcttaatgaacctactggatgaacCTggggtccgccaggctccagggGAAaaggggctggagtgggtAggccaatatGaaaaaaagatggaagtgagaaatactatgtggactctgtgaagggccgtttcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagaggcgaggacacggctgtgtatcactgtgcgagaggcgacgaatttttggaatggtaaacacttcgacccctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10025 JY8QFUQ01BIC4N unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 112 53.73 72/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10026 JY8QFUQ01AFZBJ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 85.12 183/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 7 8 12 7.8.12 [1.17.38.11] CVKDISRSGCFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'A' (1 nucleotides at position 108 to 108 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) tctggattccagttagcaactatGgccatgagctgggtccgtcaggctcctgggaaggggctggagtAgggtctcaactattagtaaagacggtgtttacacctactAaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10027 JY8QFUQ01AX71G unproductive Homsap IGHV3-30*01 F 869 88.99 194/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDSVPRASEAAYHFDY## out-of-frame + cctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattgggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10028 JY8QFUQ01B8ZVD productive (see comment) Homsap IGHV3-7*03 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctccggattcaAtttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10029 JY8QFUQ01BQGL9 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10030 JY8QFUQ01DWCPJ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKIDSRNYDFLEWLLC##W out-of-frame - ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtttattactgcgcgaaaatagatagtcggaattacgactttttggagtggttattatgcacactggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10031 JY8QFUQ01A4UD9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCGNGACHVADYW in-frame - cctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10032 JY8QFUQ01DBWXT unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 930 91.03 203/223 nt 90.58 202/223 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD5-18*01 F 3 8 10 X 8.10.X [1.17.38.11] CTTAPSETYATEYFAMDV# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ4*03 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgccCcccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctgggccaggggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10033 JY8QFUQ01B3EO7 No results +10034 JY8QFUQ01AV4S5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 620 93.01 133/143 nt 92.31 132/143 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 7 1 10 7.1.10 [1.X.38.11] CVSDLAGQKGFW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01AV4S5 ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 38 of V-REGION: 75 nucleotides (from position 27 in the user submitted sequence), (do not cause frameshift) cctcaggattcaccttcagtagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10035 JY8QFUQ01CDEOP productive Homsap IGHV4-39*02 F (see comment) 762 83.18 183/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 10 7 22 10.7.22 [1.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame + Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccctatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10036 JY8QFUQ01BJH05 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + tctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10037 JY8QFUQ01A7U9L unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt 97.33 219/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 X 10.9.X [1.17.38.11] CTRGSSRGGDMMRTTMS#DFW out-of-frame + in FR3-IMGT at codon 74 of V-REGION: 'T' (1 nucleotides at position 134 to 134 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaaTgtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcgggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +10038 JY8QFUQ01C534S No results +10039 JY8QFUQ01ARTV6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 389 75.54 105/139 nt 8 8 X 8.8.X [1.17.11.X] null - No rearrangement found Low V-REGION identity (75,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10040 JY8QFUQ01BP904 productive Homsap IGHV4-61*02 F 902 90.05 199/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 14 10.7.14 [1.17.38.11] CAREKVVIRPNWFDPW in-frame + tctctggtgactccatcaccagtggtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaatccctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagagaaaaagtagtgatccgtcccaactggttcgacccctggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10041 JY8QFUQ01B376D unproductive (see comment) Homsap IGHV3-7*01 F 896 90.37 197/218 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CARVIPGRGNYA#FDVW out-of-frame + stop codons cctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgctttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10042 JY8QFUQ01BUVXP productive Homsap IGHV4-39*02 F 920 90.95 201/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 3 10 7 14 10.7.14 [1.17.38.11] CARPGARETNNAWVDW in-frame - tctctggtggctccgtcagtaggagtgcctactactggggctggatccgccagcccccagggaaggggctggagtggattgggaccatctattatagtgggaccacatactccaatccgtccctcaagactcgagtcaccatgtccttggacacgtccaagaaccacatctccctgaagctgaattctgtgaccgccgcagacacggctgtttattactgtgcgagacctggggctagggagactaataacgcctgggtcgactggggccagggcaccctggtcaccgtctcctcggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10043 JY8QFUQ01BD2RN productive Homsap IGHV3-15*07 F 939 91.48 204/223 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD5-12*01 F 3 8 10 12 8.10.12 [1.17.38.11] CATGQRGFDAFDLW in-frame + ccctggtctcactttcagtgacgcctggatgaactgggtccgccaggctccagggaaggggctggagtggattggccgtattaagaacaacactgatggtgggacaccatactacgctgcacccgtgaaaggcagattcaccatctcaagagatgactcaaagaagacgatgtatctccaaatgaacaacctgaaaatcgaagacacagccgtgtattattgtgcgacaggacagaggggctttgatgcttttgatctctggggccaagggacactggtcaccgtctctgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10044 JY8QFUQ01CC2G5 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 160 80.0 40/50 nt Homsap IGHD6-25*01 F 3 8 7 X 8.7.X [1.17.38.11] CARGTRYNNGLD#FDVW out-of-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgctttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10045 JY8QFUQ01AHRU1 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 454 72.63 130/179 nt 8 8 X 8.8.X [1.17.25.X] null - No rearrangement found Low V-REGION identity (72,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10046 JY8QFUQ01DACIO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10047 JY8QFUQ01BC5MC productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 794 84.16 186/221 nt 83.26 184/221 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD6-13*01 F 1 10 7 21 10.7.21 [1.17.38.11] CARRLPLGSSAWLETTHDAFDIW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); tgtctggtgaatctatcgacagaaatgcttatttttggggctggatccgccagcccccaggggaggggctggagtgggttgggagtacctcttctaatggGgaacaccttctatagtccgtccctcCaaaagtcgagtcaccttgtccgtagacacgtccaggaaccttgtctccctgaacctgaggtctgtgaccgccgcagacacggctgtatattactgcgcgagacgactgcccttagggagcagcgcctggttagagacgacccacgatgcttttgatatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10048 JY8QFUQ01C4CXC No results +10049 JY8QFUQ01BM5IX No results +10050 JY8QFUQ01BHN1C productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.37.11] CAKNNNDFGDYDWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactgggggcaccgactccaaccctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10051 JY8QFUQ01CUU6H productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); gtctggattcaccttcagtgaccatggcatgcactGgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10052 JY8QFUQ01BHVUT No results +10053 JY8QFUQ01AWK5D No results +10054 JY8QFUQ01ANJX1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10055 JY8QFUQ01BTVML productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10056 JY8QFUQ01ASH2F productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 750 83.64 179/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10057 JY8QFUQ01CTBUY productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame - ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10058 JY8QFUQ01DKRQ7 productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 925 90.99 202/222 nt 89.64 199/222 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [2.17.38.11] CARGGSGGSYWNLIRDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'AG' (2 nucleotides at position 102 to 103 in the user submitted sequence), (cause frameshift); gtctctgatgactccgtcagcagtggtcgCttactactggagttgggtccggcaTgcccccagggaagggactggagtggattggtcatttctatcacattAGgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10059 JY8QFUQ01AFKF1 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARDRRGYSYEMDYW in-frame - ctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10060 JY8QFUQ01AMEKO productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 2 9 7 15 9.7.15 [1.17.38.11] CLRCHFGTGYYYYFDYW in-frame - tctggtggctccatcgccagtagtaactggtggagttgggtccgccagtccccagggaaggggctggagtggattggagagatctatcatactgggaccgtcaactacaacccgtccctcatcagtcgagccaccataggagtggacaagtccaagaatgagctctccttgaggctgacctctgtgaccgtcgcggacacggccgtatattattgtttaagatgtcactttgggactggttattattactactttgactactggggccagggattgctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10061 JY8QFUQ01BXIOU No results +10062 JY8QFUQ01DU1MH productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 1034 98.14 211/215 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-2*02 F 2 8 7 15 8.7.15 [1.17.38.11] CARGVGVSWHTEYFQHW in-frame + cctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagaggggtcggcgtcagctggcatactgaatacttccagcactggggccagggcaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10063 JY8QFUQ01AUF6C productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 810 86.18 187/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcacgtttagagactattggatgagttgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10064 JY8QFUQ01DWWER productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10065 JY8QFUQ01BPZ65 productive (see comment) Homsap IGHV3-48*03 F 796 85.65 185/216 nt 85.19 184/216 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-21*02 F 2 7 8 14 7.8.14 [1.17.38.11] CVRQTGDYYFFGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) ctctggattcgccttcaaagttttaacatgaattgggtccgccaggcttcagggaaggggccggagtggattgcatacattaatggaagagggactaacatctactatgcagactctgtgaagggccggttcaccatctccagagacaacgcccagaacgcagtgcatctgcagatggaccgcctgagagtcgaggacacggccctatattactgtgtgagacaaactggagactactatttcttcggtctggacgtctggggccaaggaaccacggtcaccgtctcttcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10066 JY8QFUQ01CQ70Y productive (see comment) Homsap IGHV3-48*01 F (see comment) 759 84.11 180/214 nt 83.64 179/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10067 JY8QFUQ01BYUWE productive (see comment) Homsap IGHV3-7*01 F 964 93.61 205/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'C' (1 nucleotides at position 146 to 146 in the user submitted sequence), (cause frameshift); gcctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtgGgactctgtgaagggccgattcaccatctcCcagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10068 JY8QFUQ01B25OW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10069 JY8QFUQ01CD5XY No results +10070 JY8QFUQ01B7DJ1 productive (see comment) Homsap IGHV3-7*01 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [2.17.38.11] CAGGRGWLIDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); gcctctggatTtcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10071 JY8QFUQ01A3PZ4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10072 JY8QFUQ01AM7GI productive (see comment) Homsap IGHV3-23*05 F 826 87.79 187/213 nt 86.85 185/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 7 7 10 7.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggatcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10073 JY8QFUQ01CZWZN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 1 8 8 16 8.8.16 [1.17.38.11] CTKDPQQLLEGVNWFDPW in-frame - cctctggattcacctttaggagctatgccatgagttgggtccgccaggctccagggaaggggctagagtgggtctcgtctatcagtggcagtggtgataagacaaagtatgcagattcagtgaggggccggttcaccatctccagagacaattacgacaacacattatatctgcgaatggagggcctgagagccgaggacacggccacatattactgtacgaaagatcctcagcaactgttggaaggggtaaattggttcgacccctggggccagggaaccctggtcaaggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +10074 JY8QFUQ01AQXZ4 productive (see comment) Homsap IGHV3-7*01 F (see comment) 693 80.18 174/217 nt 79.72 173/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaatacgaaatacttttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10075 JY8QFUQ01AN9EU productive (see comment) Homsap IGHV3-7*01 F 1008 96.31 209/217 nt 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); ctctggattcagctttagttactattGggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10076 JY8QFUQ01A87WT unproductive Homsap IGHV3-7*01 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKGGGNGDLDY## out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); acctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10077 JY8QFUQ01BPT28 No results +10078 JY8QFUQ01DJVA6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVKDISRSGCFEYW in-frame + cctctggattccagtttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10079 JY8QFUQ01B015N No results +10080 JY8QFUQ01CYHLK unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYLNL#DYW out-of-frame - ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatatttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10081 JY8QFUQ01A572X No results +10082 JY8QFUQ01AVUEZ No results +10083 JY8QFUQ01AUDTZ productive Homsap IGHV3-7*01 F 1045 97.72 214/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [2.17.38.11] CVSSPYFYDSNGYW in-frame - gcctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10084 JY8QFUQ01BHJG9 productive (see comment) Homsap IGHV4-61*02 F 893 89.59 198/221 nt 89.14 197/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggtggcctcatcagcagtggtacttactactggacttggatccggcaggccgccgGgggagggactggagtggatcggacgtgtttatattagtgggagcaccacctacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgccgctgacacggccgtatattactgtgcgagagaacatagtaggacgatgggcggggcgagagagcttgactcctggggcctgggaactctggtcaccgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +10085 JY8QFUQ01CSZEX No results +10086 JY8QFUQ01C62U1 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'T' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); cctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatTgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggttttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10087 JY8QFUQ01BIHK2 productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 934 91.44 203/222 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 10 7 18 10.7.18 [2.17.38.11] CARSAYCGADCYSADYLQHW in-frame - gtctctggtggctccgtcagcagtaggggttactactggaactggatccgccagttcccagggaagggcctggagtggattgggaacatcttttacagtgggggcacctacgacaacccgtccctcaggagtcgaatttctatatcattagacacgtctaagaaccaattctccctgaagttgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10088 JY8QFUQ01BW009 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*10 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-7*01 F (see comment) 697 80.56 174/216 nt 80.09 173/216 nt Homsap IGHJ1*01 F 125 71.15 37/52 nt Homsap IGHD1-1*01 F 1 8 8 16 8.8.16 [1.17.37.11] CSRGTTGTTDDSRLFQHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 157 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtaggttttggatgacctgggtccgccaggctccaggcaagggcctagagtgggtggctgtcataaataaggctgggaagactaaacattatatagactccgtgaagggccgattcaacgtctccagagacaactccgaaaaacactctatttggagatgaataacgtgggagttgaggacacggctgtatattattgttcgagaggtaccacggggacgacagacgactcgaggttgttccaacactggggccagggcgccctggtcaccgttttcgtcaacatccccgaccagcccccaaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +10089 JY8QFUQ01A6VCW productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggctccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10090 JY8QFUQ01C4L8V unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +10091 JY8QFUQ01BMHOE productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10092 JY8QFUQ01BFX7V No results +10093 JY8QFUQ01CR39B unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F (see comment) 700 84.62 165/195 nt 84.1 164/195 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) tgtggtgggtccttcagtggtttctactagagatgcattcgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10094 JY8QFUQ01AUUPD productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10095 JY8QFUQ01C28MT productive (see comment) Homsap IGHV3-48*01 F 995 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggntccagggaaggGggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10096 JY8QFUQ01AAR41 No results +10097 JY8QFUQ01BV26V productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatacctggtccagggcttcttccccca +10098 JY8QFUQ01A8S2Q productive Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + cctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca +10099 JY8QFUQ01CBKVX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10100 JY8QFUQ01CPNX4 No results +10101 JY8QFUQ01BOB21 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 804 92.47 172/186 nt 8 8 X 8.8.X [1.17.27.X] null + No rearrangement found ctctggattcagcttcagtagctacagtatgaactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcca +10102 JY8QFUQ01BMNFC unknown (see comment) Homsap IGHV3-13*02 F 83 52.68 59/112 nt 50.89 57/112 nt 8 X X 8.X.X [23.6.X.X] null + No rearrangement found in FR1-IMGT at codon 12 of V-REGION: 'CAGC' (4 nucleotides at position 67 to 70 in the user submitted sequence), (cause frameshift); in FR1-IMGT, from codon 22 of V-REGION: 5 nucleotides (from position 97 in the user submitted sequence), (cause frameshift) tggggaagaagcctggaccaggcaggcgatgaccacgttcccatctggctgggtgctgcagaggctCAGCgggaagaccttggggctggtcggggatgctggggccgccggatccaactccagtagtaaccagtcatggagccaccagaga +10103 JY8QFUQ01CO0B8 productive Homsap IGHV3-7*01 F 907 92.02 196/213 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-21*02 F 2 8 8 18 8.8.18 [X.17.38.11] CSRHGGYTRLYNQNVYLDYW in-frame + ggattcacatttagcaacttttggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaaaataaacccagacggaagtgagaaatactatgtggactctgtgaagggccgattcaccacctccagagacaactctagaaactcgctgtgtctgcaaatggacagcctgagagccgaggacacggctgtgtattactgttcgagacatggaggttacacgagactctacaatcaaaatgtctaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +10104 JY8QFUQ01CWGFZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDLTGYSSERNYW in-frame + ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +10105 JY8QFUQ01AL6E3 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F (see comment) 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 7 17 8.7.17 [1.17.38.11] CARVVTATIYTGSYYFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); tctatggtgcgtccttcagtgattactcctgggcctggatccgccagTcccccagggaaggggctggagtggattggagagatcaatcatagtggaagcaccaactacaacccgtccctcaagagtcgaggcatcatatcaatagacatgtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacacggctgtatattactgtgcgagagtcgtcacggctacaatttatactgggtcctactactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +10106 JY8QFUQ01CKPDD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10107 JY8QFUQ01B66MK unproductive (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 255 77.27 68/88 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 3 X X X X.X.X [X.X.29.11] CVKRSKGQQL#YYFENW out-of-frame - stop codons Low V-REGION identity (77,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggaattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctctgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10108 JY8QFUQ01DOOG7 No results +10109 JY8QFUQ01A7F9O unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 106 53.44 70/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +10110 JY8QFUQ01ACOUC productive (see comment) Homsap IGHV3-48*04 F (see comment) 786 83.86 187/223 nt 83.41 186/223 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [3.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); gcctgctggagttcagccatttagtacctattggatgggctgggtccgccagggtccagggaaggggctggagtggatttcacacattaGggggtagtagtagtaccacccactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10111 JY8QFUQ01BNMSP productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 758 82.81 183/221 nt 82.35 182/221 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 13 8.10.13 [1.17.37.11] CATDSPTGYYAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 83 of V-REGION: 1 nucleotides (from position 159 in the user submitted sequence), (cause frameshift) tctgggttcgttttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10112 JY8QFUQ01B13XW productive (see comment) Homsap IGHV1-24*01 F 988 96.24 205/213 nt 95.77 204/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); ggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggCaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10113 JY8QFUQ01C1QUY productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 855 88.48 192/217 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDGGSYNRMDLW in-frame + gtctgggttcagtttcattgactatggcatacactgggtccgccaggctccaggcaaggggctggagtggatggcaattatatggtatgatgggaaaaataaatattatgaagagtccgtgaaggaccgattcaccgtctccagagacaattccaagaacacggtgtatttggaagtgaatagtctgagagtcgacgacacggctgtgtattactgtgcgagagacggtgggagctacaacaggatggacctttggggccagggaaccctggtcaccgtctcgtcagcatccccggaccagccccaaagggtcttcccgctgagcctcgacagcaccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10114 JY8QFUQ01AGVPB No results +10115 JY8QFUQ01AM2IT unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 833 87.16 190/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARLRSFGDYP#DVW out-of-frame + stop codons cctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactacccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10116 JY8QFUQ01BU8C6 unproductive (see comment) Homsap IGHV3-48*02 F 972 94.47 205/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [1.17.38.11] CARPAGAG*PFFA#YYSGLDVW out-of-frame + stop codons ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgcatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggcagggtgacccttttttgccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10117 JY8QFUQ01AVFWE No results +10118 JY8QFUQ01BGJJ8 productive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10119 JY8QFUQ01BCAAX productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactca +10120 JY8QFUQ01CGW8W No results +10121 JY8QFUQ01B6JKZ productive Homsap IGHV3-7*03 F 837 87.56 190/217 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcacttttagtgactattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10122 JY8QFUQ01DV171 productive (see comment) Homsap IGHV4-39*03 F 929 91.36 201/220 nt 90.91 200/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcCccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +10123 JY8QFUQ01DBY0W unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F or Homsap IGHV1-69*01 F or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F 86 57.53 42/73 nt 56.16 41/73 nt X X X X.X.X [24.X.X.X] null - No rearrangement found in FR1-IMGT, from codon 7 of V-REGION: 3 nucleotides (from position 90 in the user submitted sequence), (do not cause frameshift) agttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgctctcggaggtgctcctggagcagggcgccagggggaagaccgatgggcccttggtggaggtgacgaagccaccagaga +10124 JY8QFUQ01C71OC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [1.17.38.11] CVRYDYSRLHRSNYFGPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctggattcaccttcatcagttatggcatgagttgggtccgccaggTttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10125 JY8QFUQ01BE3QC No results +10126 JY8QFUQ01AX5EL productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1030 97.69 211/216 nt 97.22 210/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10127 JY8QFUQ01BLXMI productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 973 94.06 206/219 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD1-26*01 F 1 9 7 12 9.7.12 [2.17.38.11] CARKGMGSTGWDFW in-frame - Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gtctctggtggctccatcagcagtaataactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggaaatctatcataatgggagaaccctcttcaatgcgtccctcaagagtcgagtcaccatatcagtagacaagtctaagagccagttctccctgaagttgaactctgtgaccgccgcggacacggccgtatattactgtgcgagaaaaggaatgggctctaccgggtgggacttctggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10128 JY8QFUQ01A2OQJ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); gcctctggaGttcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10129 JY8QFUQ01BF6IL productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD2-15*01 F 2 8 8 12 8.8.12 [1.17.38.11] CAKGGGNGDLDYWG in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccaggggaacccctggtcaccgtctcctcagcatcccccgaccagccccaaggttcttgcccgctgagcctcgacagnaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttcccc +10130 JY8QFUQ01A9XRP productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10131 JY8QFUQ01C67DD No results +10132 JY8QFUQ01B13IK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'A' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggAactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10133 JY8QFUQ01DGE1E productive Homsap IGHV3-21*04 F 954 93.55 203/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame - ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10134 JY8QFUQ01DBSU6 productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F (see comment) 559 73.06 160/219 nt 71.69 157/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*01 F 2 10 7 13 10.7.13 [1.17.38.11] CTRGSLTGTYPSDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (73,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'TCTGAG' (6 nucleotides at position 98 to 103 in the user submitted sequence), (do not cause frameshift); in CDR2-IMGT, from codon 60 of V-REGION: 6 nucleotides (from position 97 in the user submitted sequence), (do not cause frameshift) ttcggagacgatatatctggagacagtgttacttggaactggatcaggcagTcccccagggagggggcttgagtggctcgggcgtatctttcacaggTCTGAGtggcataccgactacttggcgtctgttagaggccgaatctccatggatgtcgacacgtccaagaaccacttcaccctgcagctccgctctctgactcccgacgacacggctacatatttctgtacaagaggctctctaactgggacatatccttctgaccactggggtctggggaccccagtgaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10135 JY8QFUQ01CNWHA unproductive (see comment) Homsap IGHV3-7*03 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKNRI*ITLAGTA#FDYW out-of-frame - stop codons in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtggctattggatgagttgggtccgccaggctccagGggaagggtctggagtgggtggccaacatagagaaagatggaagtgacataaagtatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagctgaggacacggccttgtattactgtgcaaaaaatcggatataaataacattggctggcacggcctatttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10136 JY8QFUQ01BQX07 No results +10137 JY8QFUQ01COS53 productive Homsap IGHV3-72*01 F 961 92.79 206/222 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD7-27*01 F 1 8 10 10 8.10.10 [1.17.38.11] CVRDPFSSRGHW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggattcatcctcagtgactaccacatggagtgggtccgccaggctccagggaaggggctggagtgggttggccgtagtagaaagaaagctaatagttacagtacagaatatgccgcgtctgtgaaaggcagattctccatttcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaatcgacgacacggccgtgtattattgtgtcagagaccccttctcaagtcggggccactggggccagggaaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10138 JY8QFUQ01C70M7 productive (see comment) Homsap IGHV3-7*01 F 733 95.06 154/162 nt 94.44 153/162 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 0 11 8.0.11 [1.17.27.11] CAKGGGNGDLDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 56 of V-REGION: 55 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa +10139 JY8QFUQ01CN6A2 unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 172 57.53 84/146 nt 8 8 X 8.8.X [1.17.14.X] null + No rearrangement found ctctggattcatctttgatgattttggcatgagatgggtccgccaagttccggggaaggggctacagtgggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +10140 JY8QFUQ01CRPO4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 830 86.43 191/221 nt 85.97 190/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [2.17.38.11] CAKDYGDCRGGICYAEPLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); tagcctctggattcaGcctcgccgacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtatatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10141 JY8QFUQ01C8TZM unproductive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaagggtcttcccgctgagcctcgaccagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +10142 JY8QFUQ01C0F74 productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca +10143 JY8QFUQ01A3FLZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10144 JY8QFUQ01B21SF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10145 JY8QFUQ01CTRZY unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10146 JY8QFUQ01CZKTN productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 803 85.07 188/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 3 10 7 11 10.7.11 [1.17.38.11] CAGGEDPFKVRHW in-frame + tctctggtggctccttttctaatcatggttaccactgtagttggctccgccagttcccagggaaggacctggagtggattgcctacatctattacactgggagcaccgagtataacccgtccctcaggagtcgagttgccatatcagtggacacgtctgggaaccagtgttccctggagttgaactctgtgagtgccgcggacacggccgtctattactgtgcgggaggcgaggatcccttcaaagttcgacactggggccagggaacccgggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10147 JY8QFUQ01BFEHI productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 813 86.92 186/214 nt Homsap IGHJ1*01 F (see comment) 188 84.62 44/52 nt Homsap IGHD1-26*01 F 1 8 7 13 8.7.13 [1.17.38.11] CVGVGVGSSVSFQYW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcactgtcaataacaactacatgggttgggtccgccaggctccagggaaggggctggagtgggtctcgactatttattacggtggcaccacatattacgcagactccgcgaagggccgattcaccatctccagagacacctccaggaacacactttttcttcagatgaacagcctgagaagcgacgacacggctctatattattgtgtgggagtcggagtgggatcttcagtctccttccaatactggggccagggcacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10148 JY8QFUQ01B9QQ1 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 259 59.28 115/194 nt 58.76 114/194 nt 8 8 X 8.8.X [1.16.30.X] null + No rearrangement found Low V-REGION identity (59,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtaaccattggatgaactggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10149 JY8QFUQ01DJU8W No results +10150 JY8QFUQ01BXIV3 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 872 87.5 196/224 nt 85.71 192/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-14*01 ORF 2 8 10 13 8.10.13 [2.16.38.11] CNADVPSPLAQNDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 61 of V-REGION: 'A' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'G' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) gcctctgggttcGattttcagtgatgcctggatgagttggtccgccaggctccagggaaggctctggagtgggttgcccgtataaaaacttttggtgAacggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcGaaaaaaaaggctgtatctgcaaatggacagcctgagaatcgaggacacagccaagtattactgcaacgcagatgtcccgtcaccattagcgcaaaatgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10151 JY8QFUQ01B8YBT No results +10152 JY8QFUQ01CP6NE No results +10153 JY8QFUQ01A2E3L No results +10154 JY8QFUQ01BY2RR productive (see comment) Homsap IGHV3-9*01 F (see comment) 789 84.55 186/220 nt 84.09 185/220 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [2.17.38.11] CGRIAKPGLGALDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); gggcgttggattcacttttaatgGaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctggggccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10155 JY8QFUQ01DNHX4 No results +10156 JY8QFUQ01BST4Q No results +10157 JY8QFUQ01CBBPX productive (see comment) Homsap IGHV3-74*03 F 846 88.02 191/217 nt 87.1 189/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); ctctggattcacGtttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaAagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10158 JY8QFUQ01DOUFW productive (see comment) Homsap IGHV3-33*03 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10159 JY8QFUQ01BF7RI unknown (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 810 86.18 187/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10160 JY8QFUQ01BQZYK productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 922 90.22 203/225 nt 89.78 202/225 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 2 8 10 15 8.10.15 [2.17.38.11] CTTDRRGLSIPPQFDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 98 of V-REGION: 'G' (1 nucleotides at position 205 to 205 in the user submitted sequence), (cause frameshift); gcctctggattcactttcagtgacgcctggatgagctgggtccgccagattccagggaaggggctggagtgggttggccgtataaaaaacaaagctatgggtgagacaacagacttcgctgcacccgtgagaggcagattcagtatctcaagagatgattcaaaaaatacactgtatctgcacatgagtggcctgaaaaccgagGgacacagccgtctattattgtaccacagatcggcggggtttgtctataccacctcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10161 JY8QFUQ01B40GM productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10162 JY8QFUQ01BXD0I productive Homsap IGHV4-39*03 F 919 91.28 199/218 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - tccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10163 JY8QFUQ01CM17V productive (see comment) Homsap IGHV3-33*03 F 931 92.59 200/216 nt 91.67 198/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 7 12 8.7.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattGcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10164 JY8QFUQ01C05EA No results +10165 JY8QFUQ01A1RAE productive Homsap IGHV3-30*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [1.17.38.11] CPKTGPGHSSPFDYW in-frame + ctctggattcaccttccgaagttatgatctgcactgggtccgccaggctccaggcaaggggctagagtgggtggcatttatttcaaacgatggaagtgacacagactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaagacgctatatctgcaaatgaacagcctgagagttgaggacacggctgtgtattactgtccgaaaaccggccccggtcatagcagcccctttgactactggggccagggaaccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10166 JY8QFUQ01A2C1P productive (see comment) Homsap IGHV3-48*01 F 972 94.47 205/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-2*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARGRCSSSNCKPLYGEFGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtgggAtttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagccgaagacacggctatatattactgtgcgcgaggaagatgtagtagttccaattgtaagccactttacggtgaatttgggtattggggccagggaaccccagtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10167 JY8QFUQ01C5UF8 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaacttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10168 JY8QFUQ01AFE74 productive Homsap IGHV3-9*02 F 896 90.37 197/218 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + cctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10169 JY8QFUQ01DCDMJ unproductive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD2-8*02 F 1 8 8 X 8.8.X [0.17.38.11] CARDGYLPGNGADF# out-of-frame - tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttgggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10170 JY8QFUQ01A921B unproductive Homsap IGHV1-18*01 F 885 90.65 194/214 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [0.17.38.11] CARVIRTNWL#PL out-of-frame + tggttacacctttactacctatggcgtcacctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggtaatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacagccgtatattattgtgcgcgagtgattcggaccaactggctcgacccctgggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +10171 JY8QFUQ01AR8K0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 901 90.41 198/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARRTITAAGRGDDYW in-frame - gcctctgaattcacctttagcagttttgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagcattggtactagtgttgttaacacatggtacgcagactcagtgaagggccggttcgccatttccagagacaattccaagagcacgctgtatttgcaaatgaatagcctgagagtcgaggacacggccgtatattactgtgcgaggaggacaataacagcagctggccgtggggatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10172 JY8QFUQ01BYPPR No results +10173 JY8QFUQ01AIJHN No results +10174 JY8QFUQ01A6JS9 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggGggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +10175 JY8QFUQ01C7QCP No results +10176 JY8QFUQ01DGUMB No results +10177 JY8QFUQ01DHRFR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 886 90.28 195/216 nt 89.35 193/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 79 of V-REGION: 'CATCC' (5 nucleotides at position 139 to 143 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 164 to 164 in the user submitted sequence), (cause frameshift); tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgccagggccggttgcgatcCATCCtccagagacaattcgaagaaTcacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10178 JY8QFUQ01A11F6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10179 JY8QFUQ01BPGLO No results +10180 JY8QFUQ01CEIJB unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDQRSGDA#EAFDIW out-of-frame + stop codons ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaaggtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10181 JY8QFUQ01C0K2G No results +10182 JY8QFUQ01CUANG productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 939 93.46 200/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 21 8.8.21 [0.17.38.11] CARGWLTAADTGVASGHDWFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggatacaccttcaccagctactatatgcactggatacgacaggcccctggacaagggcttgagtggatgggaataatcaaccctagtggtggtaccacaaggtacgcacagaagttccagggcagagtcttcatgaccagagacacgtccacgagcacagtccacatggaggtgaacggcgtaagatctgacgacacggccgtgtattactgtgcccgagggtggctgacagcagctgataccggggtggcgtcagggcacgattggttcgactcctggggccagggaaccctggtaaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +10183 JY8QFUQ01B07O4 productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame + ctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttgcctcagcatcccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttcccccga +10184 JY8QFUQ01ALWT0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1030 97.69 211/216 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGPHQYYFDYW in-frame - tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10185 JY8QFUQ01C9SSW No results +10186 JY8QFUQ01AZHT9 productive (see comment) Homsap IGHV3-7*01 F (see comment) 707 80.73 176/218 nt 80.28 175/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 67 of V-REGION: 'T' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); cctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatcccccagacggaatacgaaatactTttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10187 JY8QFUQ01CMWLP productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10188 JY8QFUQ01C5L8H productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10189 JY8QFUQ01DHKZJ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1001 95.02 210/221 nt 94.57 209/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 2 10 7 12 10.7.12 [1.17.38.11] CVRHRRLELLPDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'A' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagcagtaatagtttctactAggggctggatccgccagcccccagggaaggggctggagtggattgggaatatctattatagtgggagcacctactacaacccgtccctcgagagccgagtcaccatatccgtagatacatccaggaaccagttctccctgaagctgaggtttgtgaccgccgcagacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10190 JY8QFUQ01A5OYB No results +10191 JY8QFUQ01AZOIS productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 609 96.92 126/130 nt 96.15 125/130 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 7 X 15 7.X.15 [1.X.35.11] CTRELRLAAARDGVDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 84 nucleotides (from position 26 in the user submitted sequence), (do not cause frameshift) ctctgggttcaccgtcagtagcaaagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatttggggccaagggacaatggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10192 JY8QFUQ01DI435 No results +10193 JY8QFUQ01BNTHD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10194 JY8QFUQ01AZ89E productive Homsap IGHV4-61*02 F 1028 96.38 213/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 15 10.7.15 [1.17.38.11] CARAPSYTNSHQHCDYW in-frame + tctctggtggctccatcaacagtggtagttactactggagttggattcggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctattattgtgcgagagctccctcttataccaactcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatcccgacagccccaaggtcttcccgctgagcctcganagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +10195 JY8QFUQ01DKUXC No results +10196 JY8QFUQ01A63GT unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD5-24*01 ORF 1 8 7 9 8.7.9 [4.17.38.11] CARGAPFS**C in-frame + stop codons ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10197 JY8QFUQ01DIBNC productive (see comment) Homsap IGHV4-61*01 F 1100 100.0 221/221 nt 99.1 219/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtGgggagcaccaactacaaCcccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccctatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggcccctgggctgcctggtcaaggactacttccccagaaccggtgacggtgtcgtggaactcag +10198 JY8QFUQ01CQCPA unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAGAEAGL#DYW out-of-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtatatttctgtgcgggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10199 JY8QFUQ01B8E5L productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +10200 JY8QFUQ01CKO0V No results +10201 JY8QFUQ01CBSKZ unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F 766 93.64 162/173 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found ctctggattcaccttcagtgactattacatgggctggatccgccaggctccagggaaggggctggagtgggtttcatccattagtaatagtgctagtaccatgtacctggcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaactcactgcatctgc +10202 JY8QFUQ01ALS9D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10203 JY8QFUQ01BFWUZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaac +10204 JY8QFUQ01AGZTV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10205 JY8QFUQ01BM96X productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDWPSSGWSHFEAW in-frame + ctctggattcacctttgatgagcatgccatgcactgggtccggcaagttccggggaagggcctggagtgggtctctggtgttacttggaatagtggtgtcatagactatgcggactctgtgaagggccgattcaccatctccagagacaacgccaggaattccctgtatctacaaatgaacagtctgagaactgatgacacggccttctatttctgtgcaaaagattggccgagcagcggctggtcccattttgaggcttggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10206 JY8QFUQ01A8BAL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10207 JY8QFUQ01CI0IM No results +10208 JY8QFUQ01DEIA7 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10209 JY8QFUQ01A7Z2B productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + gttctggatacatgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10210 JY8QFUQ01BH96D productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10211 JY8QFUQ01A1OLP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10212 JY8QFUQ01B7YIT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10213 JY8QFUQ01A1OIA No results +10214 JY8QFUQ01CLBGL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 874 89.04 195/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKVMWGVTGPIDPFDYW in-frame - gcctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtaagtagtaggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10215 JY8QFUQ01B9KF0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame + ctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccccca +10216 JY8QFUQ01CAQNJ No results +10217 JY8QFUQ01DK1AF unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 951 92.73 204/220 nt 91.36 201/220 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [2.17.38.11] CARPAFSGSGTYRP#DGFDVW out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); ggtttctggatacagcCtttaccaattactggatcggctgggtgcgccaggtgcccggCaaaaggcctggagtggatCggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcagtaccgcctaccttcagtggagcagtctagcgacctcggacaccgccatgtattactgtgcgagaccagctttctctggttcggggacttaccggccgaggatggttttgatgtctggggccaaggaacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10218 JY8QFUQ01CEV8W unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD5-12*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDLYGADDL# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +10219 JY8QFUQ01AGRP6 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-7*01 F 3 8 8 13 8.8.13 [1.17.38.11] CATGAGNWNYIFNYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); cctctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtggtttttGatatatactacgcggattcagtgaagggccgagtcaccatctccagagacaacgccaagaattcgctatttctgcaaatgaacaacctgcgagccgaggacacggctgtctattactgtgcgacaggggccggaaactggaattacatttttaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10220 JY8QFUQ01AMBE4 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 271 67.97 87/128 nt 8 8 X 8.8.X [1.17.8.X] null - No rearrangement found Low V-REGION identity (67,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10221 JY8QFUQ01BFV12 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 877 89.81 194/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF## out-of-frame - tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgcttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccc +10222 JY8QFUQ01AKRWC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame + ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggaccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10223 JY8QFUQ01CIF2W productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +10224 JY8QFUQ01AVT39 productive Homsap IGHV3-7*03 F 837 87.56 190/217 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcacttttagtgactattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +10225 JY8QFUQ01ABWTO No results +10226 JY8QFUQ01AGX2K No results +10227 JY8QFUQ01A4OCK unknown (see comment) Homsap IGHV3-74*03 F 126 51.21 106/207 nt 8 6 X 8.6.X [1.17.36.X] null + No rearrangement found ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10228 JY8QFUQ01ABDY1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame + ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +10229 JY8QFUQ01CZVW2 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 963 94.01 204/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDAFEMW in-frame + ctctggattcacctttgatgattttggcatgagttgggtccgccaagttccagggaaggggctggagtgggtcgctggtatcagttggaatggaggcaaaacaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcattgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10230 JY8QFUQ01B0GPK productive Homsap IGHV3-7*01 F 1026 97.24 211/217 nt Homsap IGHJ6*02 F (see comment) 188 78.69 48/61 nt Homsap IGHD6-13*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARERQLNNGMDVW in-frame + Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) ctctggattcacctttagtagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggcccacataaagcaagatggaagtgtcaaataccaagtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagagcggcagcttaataacggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10231 JY8QFUQ01DSJLM unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1057 99.07 214/216 nt 98.15 212/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [2.17.38.11] CARLGARFGD#DYW out-of-frame - stop codons in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttcctaCctggagctGggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10232 JY8QFUQ01C1UC1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [1.17.38.11] CANEVGYCSG## out-of-frame + in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgTtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccgaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10233 JY8QFUQ01ADRL4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 797 85.32 186/218 nt 84.86 185/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-20*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGLTTMTGNGLEHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift); tctctggattcacccttcgcagatatggcatggcgtgggtccgccaggctccggggGAagggggctggagtgggtctcatcttctaacagtagtgatgaatccacatactatgcagactccgtgaagggccgcttcaccatttccagagaccattccaagaacacggtgtttttgcaaatgtacagcctgagagccgaagacacggccctctattactgtgcgagagggctaacaacaatgacagggaatggtcttgagcactggggccagggagccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10234 JY8QFUQ01CSA9Y productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.16.38.11] CARHGSGWLQELDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtggctccatcatcagagacagtgcctactggggctggatccgccagccccagggaaggggctggagtggcttgggagcatctattatagtgggagtacctactacaatccctccctcaagagtcgagtcaccatatccgtagacacgtccaagaagcagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagacatggcagtggctggctccaggaacttgactactggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10235 JY8QFUQ01BIKPK productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10236 JY8QFUQ01CCVD9 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 634 76.85 166/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (76,85% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10237 JY8QFUQ01COMBA productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'AG' (2 nucleotides at position 75 to 76 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgGgggagggggctggagtgggtcAGtctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10238 JY8QFUQ01DME6J productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 696 80.84 173/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcaatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +10239 JY8QFUQ01A6K87 unproductive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 9 7 12 9.7.12 [1.17.38.11] CAANLGHGSYFKYW in-frame - stop codons in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggtgactccgtcagcagtgataactagtggaGgttgggtccgccagaccccagggaaggggctggagtggattggagaaatctatcatggtgggaccaccaactacaatccgtccctcaagggtcgagtcaccttatcggtcgacaagtccaagaaccaattctctctgagaatgacctcttttaccgccgcagacacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10240 JY8QFUQ01BJCRY No results +10241 JY8QFUQ01B76II productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10242 JY8QFUQ01CFMZ4 No results +10243 JY8QFUQ01CC6BC productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 973 92.11 210/228 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [2.17.38.11] CARGGDYYDSGGLDYW in-frame + tctccgggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtgattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +10244 JY8QFUQ01CPBOV productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 809 86.51 186/215 nt 85.58 184/215 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [1.17.37.11] CARGDGYNFGGLDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 105 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 121 in the user submitted sequence), (cause frameshift) ctatggattcaacttcattggttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatctttatgcagactccgtgagggccgatccatcatttccagagacgattctaaaagaacactgtttctccaaatggacaacctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +10245 JY8QFUQ01APAZK No results +10246 JY8QFUQ01AU2HD productive Homsap IGHV3-7*01 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10247 JY8QFUQ01DNPPJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10248 JY8QFUQ01BGGO2 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt 88.48 192/217 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-26*01 F 3 8 8 21 8.8.21 [1.17.38.11] CVKDLGSYGSPWRAYYYYGMDAW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); ctctggattcGaccctcaacagcCaatggcatgcactgggtccgccagactccagacaaggggctggagtgggtggcagtgatttcatatgatggaaatgataaatactatggagatgcagtgacgggccgattcaccatctccagagacacttccaagaacacagtatatctggagatgtacagcctgagacctgaggacacggctgtgtattactgtgtgaaagatcttgggagttacggtagtccttggcgcgcctactattactacggcatggacgcctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10249 JY8QFUQ01CMMRS No results +10250 JY8QFUQ01CVL1P productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 863 89.3 192/215 nt 88.37 190/215 nt Homsap IGHJ1*01 F 215 90.38 47/52 nt Homsap IGHD5-12*01 F 3 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); cctctgacttaaTcggtcagtgacaattaGcatgagttgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacggttcccagaacacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtatttttgtgcgagtggtggttattcgggctcgggtgaatatttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10251 JY8QFUQ01BIM6Q productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1071 99.54 216/217 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARLHGYCGGGYCYDWYFDLW in-frame + ttctggatacagctttaccagctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgattccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgagactccatgggtattgtggtggtggttattgctacgactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +10252 JY8QFUQ01DJHPK No results +10253 JY8QFUQ01DNM3T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 917 92.09 198/215 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.38.11] CAKGYSSGWYDFDCW in-frame + ctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10254 JY8QFUQ01A4V0H No results +10255 JY8QFUQ01BK76H productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 917 90.18 202/224 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [3.17.38.11] CAKEEFDTGWTQPGDW in-frame - gtgcagcctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10256 JY8QFUQ01CO056 No results +10257 JY8QFUQ01ABPW8 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcgacgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10258 JY8QFUQ01A4J2Q productive (see comment) Homsap IGHV3-66*02 F, or Homsap IGHV3-66*03 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-25*01 F 1 8 7 11 8.7.11 [2.17.38.11] CARDGRGGDLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); agtgtctgggttctccgtcagtttcaactacatgagctgggtccgccaggctccagggaaggGggctggagtgggtctcagttatctatgccgatggaagtacattctatgcagactccgtgaagggccgattcatcatctccagagacaattcaaagaacacgctcaatcttcaaatgaatagtttgagagttgacgacacggctgtgtattactgtgcgagagatgggcgcggcggtgaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10259 JY8QFUQ01BTATM unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 85 80.77 21/26 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found ctctggattcagcgtcaacaacaaca +10260 JY8QFUQ01BHA3Z No results +10261 JY8QFUQ01BYQCI No results +10262 JY8QFUQ01DT4IK productive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*11 F or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 840 88.32 189/214 nt 87.85 188/214 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 17 8.8.17 [0.17.38.11] CASDREDTAMITAESFNIW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); tggaggcaccttcagtagacatgctatcaactgggtgcgacaggcccctggacaagggcttgagtggatgggagggatcaaccccaCtccttcatacaaccaaatatgcacagaggttccagggcagagtcacatttaccgcggacgaatccacggccacagtctacatgcaactgagcagcctgggatctgaagacacggccgtctattattgtgcgagcgatcgggaagatacagctatgattaccgcggagagttttaatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcctgcctggtccagggcttcttcccccag +10263 JY8QFUQ01C2EJV productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccattggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +10264 JY8QFUQ01BGKVU No results +10265 JY8QFUQ01AZUCW No results +10266 JY8QFUQ01B507I No results +10267 JY8QFUQ01C5VRD No results +10268 JY8QFUQ01AJVZE unknown (see comment) Homsap IGHV4-61*02 F 893 89.59 198/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10269 JY8QFUQ01AEIW4 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 932 92.2 201/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - cctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaaatgaacgcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10270 JY8QFUQ01CNH24 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 930 92.99 199/214 nt 91.59 196/214 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [0.17.38.11] CAARIDSGHYWNAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'A' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); tggatacagtttcaccaactactggatcggctCgggtgcgccagatgAcccgggaaaggcctggagtggatgggtatcatctatcctggtgactctgatacccggtacaacccgtccttccaagGgccaggtcaccttctccgtcgacaagtccatcaacaccgcctacctgcagtgggacagcctgaagacctcggacaccgccaagtattactgtgcggcgagaattgatagtggtcattactggaatgctttcgatatatggggccaagggacgatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10271 JY8QFUQ01DBH5A productive (see comment) Homsap IGHV1-2*04 F 925 92.96 198/213 nt 92.02 196/213 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 14 8.8.14 [0.17.37.11] CTRDTSLDNGAALDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) tggatacaccttcaccgactactatatgcactgggtgcgacagGgccccaggacaagggcttgagtggatgggatggatcaaccctaaaagtggcggcacaaattatgcacggaagtttcaggctgggtcaccatgaccagggacacatccatcaacactgtctacatggagttgagcaggttgaaatctgacgacacggccatttattactgtacgagggatacttctttggacaacggagccgctcttgatatttggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10272 JY8QFUQ01BMOQ4 productive Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 740 81.82 180/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARVWVAGSRDENFDSW in-frame + Low V-REGION identity (81,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgggtgcttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgccctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10273 JY8QFUQ01BLHGO unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 946 92.69 203/219 nt 91.78 201/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); gcctccggattcaccGtttagtagttactGggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10274 JY8QFUQ01BIGVU unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 8 21 8.8.21 [1.17.38.11] CAKDPLYYDFVWGSYRYQSLDY* in-frame + stop codons ctctggattcacctttaccgcctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactataagtggtagtggtggtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcccctgtattatgatttcgtttggggaagttatcgttatcaatcccttgactactgaggccagggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10275 JY8QFUQ01DFPT2 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 872 89.35 193/216 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 7 X 8.7.X [2.17.38.11] CARDRQSWR#DSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcaccgtcagtaacaactacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggtgacacatactacncagactccgtgaagggccgattcaccatctccagagacaacgccaagaatacactttttcttcaaatgacttccctgagagtcgaagatacggccatttattactgtgcgagagatcgtcagagctggcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10276 JY8QFUQ01C6DVB productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAKDFYYGCDYW in-frame - ctctggattcaacttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagtcattgcatacaatggaggaaatatatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaaggataccctgtacttgcacatgaccagtctgagacctgatgacacggccatgtattactgtgcgaaagacttttattatggttgcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10277 JY8QFUQ01A0LMF No results +10278 JY8QFUQ01AHVFU No results +10279 JY8QFUQ01B92XS unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKLGWQLLLG#FFDYW out-of-frame + tctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactcag +10280 JY8QFUQ01DLY9L No results +10281 JY8QFUQ01AO340 No results +10282 JY8QFUQ01DXFVY unproductive Homsap IGHV3-48*01 F (see comment) 769 84.26 182/216 nt 82.87 179/216 nt Homsap IGHJ1*01 F 125 71.15 37/52 nt Homsap IGHD5-12*01 F 1 8 7 X 8.7.X [2.17.37.11] CSRDGRRGYDLDS## out-of-frame - Low V-REGION identity (84,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 69 of V-REGION: 'A' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 94 of V-REGION: 1 nucleotides (from position 187 in the user submitted sequence), (cause frameshift) agcctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagaAttctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcgagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctgggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10283 JY8QFUQ01BH18R productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame + ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggaccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10284 JY8QFUQ01BO6JQ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 887 89.91 196/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 17 to 18 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) gcctcctggattcaccCTttgggttattatggcatgactgggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10285 JY8QFUQ01ANK2A No results +10286 JY8QFUQ01B9WVJ productive Homsap IGHV3-21*04 F 954 93.55 203/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 163 76.79 43/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSHQVDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcgacttcagtagatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttgatagtaattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaattcgctgtttctgcaaatgaacagcctgagagccgatgacacggccgtgtattactgtgcgagagccgtgtcgcatcaggtggacgtctggggccaaggggccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagga +10287 JY8QFUQ01BRXEL No results +10288 JY8QFUQ01BLWC3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 952 94.37 201/213 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [X.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10289 JY8QFUQ01AW74R unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 640 85.55 148/173 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgc +10290 JY8QFUQ01CXKT7 productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10291 JY8QFUQ01CZJSX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt 85.19 184/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-20*01 F 1 8 8 14 8.8.14 [1.16.38.11] CARGLTTMTGNGLEHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 32 in the user submitted sequence), (cause frameshift) ctctggattcacccttcgcagatatggcatggcgtggtccgccaggctccggGggaaggggctggagtgggtctcatcttctaacagtagtgatgaatccacatactatgcagactccgtgaagggccgcttcaccatttccagagaccattccaagaacacggtgCtttttgcaaatgtacagcctgagagccgaagacacggccctctattactgtgcgagagggctaacaacaatgacagggaatggtcttgagcactggggccagggagccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctcgtccagggcttcttccccca +10292 JY8QFUQ01AYEWF unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift); caggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgCtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10293 JY8QFUQ01CPINH No results +10294 JY8QFUQ01AH8WJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca +10295 JY8QFUQ01AF6K3 productive (see comment) Homsap IGHV3-9*01 F 835 88.26 188/213 nt 87.79 187/213 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [0.16.38.11] CARTYGDHDGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift) tggattcacctttgacgactatggcatgcactggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10296 JY8QFUQ01B1EKF productive (see comment) Homsap IGHV3-69-1*01 P 915 92.89 196/211 nt 92.42 195/211 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 11 8.7.11 [1.16.38.11] CARSGSGSHLDYW in-frame + Potentially, because of detected insertion/deletion however the closest V is a pseudogene in FR2-IMGT, from codon 55 of V-REGION: 3 nucleotides (from position 77 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcagtgactacagcatgaactgggtccgccaggctccagggcaggggctggagtgggtctcatatagtcgcggaagaaccacatactacgcagactctgtgcagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10297 JY8QFUQ01C48XK productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10298 JY8QFUQ01AE2LT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame - ctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10299 JY8QFUQ01CXEQL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD5-18*01 F 3 8 8 12 8.8.12 [1.16.38.11] CVKDDGDNYGFHHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 55 of V-REGION: 3 nucleotides (from position 78 in the user submitted sequence), (do not cause frameshift) cctctggattcgcctttagcagctgtgccttgggctgggtccgccaggctccagggaaggggctggagtggatctcaggtagtggtagtagtgatagtccatattatgcagactccgtgaagggccgcttcaccatctccagggacaattccaggaacacaatctatctgcaaatgaacagcctgagagccgaggacacggccgtttattactgtgtgaaggatgacggagacaactatggttttcaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +10300 JY8QFUQ01DCZ0B No results +10301 JY8QFUQ01BUWTQ No results +10302 JY8QFUQ01DR4UR productive (see comment) Homsap IGHV4-61*03 F 880 88.74 197/222 nt 88.29 196/222 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 10 7 12 10.7.12 [2.17.38.11] CTRHPKSNVEGDSW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); tgccctggtggctccgtcagcaGgtggtagttatttctggagctggatccggcagcccccagggcaggggctggaatggatcggttatgtctataacaatgggaacaccaattacaacccttccctcaagagtcgagtcaccatttctatagacacgtccgagaatcacgtctccctgaagctggcctctgtgaccgctgcggacacggccgtgtactactgtacgaggcacccgaagtctaatgtagagggtgactcctggggccagggagccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10303 JY8QFUQ01BLHK3 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARDRRGYSYEMDYW in-frame - ctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10304 JY8QFUQ01CU6ZB No results +10305 JY8QFUQ01CJBIY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVSDLAGQKGFW in-frame - aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10306 JY8QFUQ01C28AG unknown (see comment) Homsap IGHV3-23*02 F, or Homsap IGHV3-23*03 F (see comment) 215 63.71 79/124 nt 8 8 X 8.8.X [1.17.7.X] null + No rearrangement found Low V-REGION identity (63,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtcccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10307 JY8QFUQ01CRJU3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10308 JY8QFUQ01AMPYU productive Homsap IGHV4-39*02 F 834 86.82 191/220 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10309 JY8QFUQ01BYP3T No results +10310 JY8QFUQ01AP0OV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFD#PW out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10311 JY8QFUQ01AR68Q unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 840 88.32 189/214 nt Homsap IGHJ1*01 F 152 76.92 40/52 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [0.17.38.11] CTRVGTFNWF#PW out-of-frame - tggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10312 JY8QFUQ01AJ3A7 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt +10313 JY8QFUQ01AS6WG No results +10314 JY8QFUQ01AH911 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 993 96.26 206/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARPGVGASSFIDFW in-frame + tggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10315 JY8QFUQ01B7IPI No results +10316 JY8QFUQ01AXJRF productive (see comment) Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt 81.19 177/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattccCccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10317 JY8QFUQ01BBMXO productive Homsap IGHV3-64*04 F 894 91.12 195/214 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [0.17.38.11] CSNGYGDFPRRW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10318 JY8QFUQ01BS22J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGHSYYVSSGPDYW in-frame + ctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +10319 JY8QFUQ01AJVK8 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggGaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10320 JY8QFUQ01AULWJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccagggaaggggctggagtggatctcatccattagtagtagtggtttttatatatactacgcggactcagtgaagggccgagtcaccatctccagagacaacgccaagaactcgctatctctgcaaatgagcaacctgcgagccgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10321 JY8QFUQ01DUGP5 productive (see comment) Homsap IGHV4-61*02 F (see comment) 600 75.0 165/220 nt 74.55 164/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-18*01 F 1 10 7 15 10.7.15 [1.17.37.11] CAIVDTNLVSATGKDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (75,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 87 of V-REGION: 1 nucleotides (from position 170 in the user submitted sequence), (cause frameshift) tttctggtggcccgatcaaaagtcctgattaccattggacgtggatccggcaggccgccgggaaggggctggagtgggtcgggcgtgtctatatgactggctatgtcgagaacaatccatccctctccgggcgtctctccatgtcgattgacacggcgaagaatcagtttctatgacattgacttctgtgaccgccgcagacacggccgtgtattattgtgcaatagtggacacaaatttggtttcggcgaccggtaaagactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10322 JY8QFUQ01DV2OJ No results +10323 JY8QFUQ01DES1Q productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 592 91.49 129/141 nt 90.78 128/141 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 3 8 X 13 8.X.13 [1.2.35.11] CARGRYGDQVTWDYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 41 of V-REGION: 76 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctataccttgagttggatgcagtgaagggccgattcaccatttccagagacaacgccaagaactccctctctctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagaggtcgctacggtgaccaagtaacctgggactactggggccagggcaccctggtcaccgtctcctcagcatccccggaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10324 JY8QFUQ01DRLVX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 870 90.52 191/211 nt 89.1 188/211 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 7 8 13 7.8.13 [X.17.37.11] CAKGYSSGWYDFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 118 in the user submitted sequence), (cause frameshift) ggatcacctttagtagatttgccatgacctgggtccgtcaggctccagGgcaaggggctggagtgggtCgtcaactattcattataatggtgataacacatactacgcagactccgtgagggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10325 JY8QFUQ01DKQM5 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 734 81.65 178/218 nt Homsap IGHJ6*01 F (see comment) 106 64.41 38/59 nt Homsap IGHD6-6*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKVDSSSAWDY# out-of-frame + Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcaagtttcatgaatatgccatgatctgggtccgccaggctccaggcaagggtccggaatgggtctcgtctattagtagtactagtaaatacatctattatgcacagtcagtggagggccgattcaccatctccagagacgacgccgagaacgcactgttcctccagatgagcagcctgagtgtcgacgacacggctatctattactgcgcgaaagtcgatagcagttcggcctgggactattggggcccgggaacctggtcaccgtctcttcagcatccccgaccagccccaaggtcttccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10326 JY8QFUQ01DEKM7 productive (see comment) Homsap IGHV3-72*01 F 961 92.79 206/222 nt 92.34 205/222 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.16.38.11] CITSFGGRSLAYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10327 JY8QFUQ01CJWXV No results +10328 JY8QFUQ01CCEY2 productive Homsap IGHV3-21*04 F 963 94.01 204/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 163 76.79 43/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSHQVDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcgacttcagtagatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttgatagtaattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcgctgtttctgcaaatgaacagcctgagagccgatgacacggccgtgtattactgtgcgagagccgtgtcgcatcaggtggacgtctggggccaaggggccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10329 JY8QFUQ01AXGG1 No results +10330 JY8QFUQ01BGPMP productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +10331 JY8QFUQ01CGQYY productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10332 JY8QFUQ01BEBC3 unproductive Homsap IGHV4-61*02 F 884 89.14 197/221 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CARDFWRFLQFSG#YW out-of-frame + tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10333 JY8QFUQ01CAHIJ productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 944 91.52 205/224 nt 90.62 203/224 nt Homsap IGHJ4*02 F 184 90.91 40/44 nt 8 10 6 8.10.6 [1.17.38.11] CTTESAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 134 to 134 in the user submitted sequence), (cause frameshift); tctctgcattcactttcagtaatgcctggatgacctgggtccgccaggctccagggaaAggggctggagtggcttggccgtattaaaaggaaagttgatggtgagacaacagactacgctgcatccgtgaaagGgcagattcaccatctggagagatgactcaaaaaacactctatatctgcaaatgaacagcctggaacccgaggacacagccgtatattattgtaccactgaatctgcctattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10334 JY8QFUQ01CVA0Q unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.16.38.11] CARKRVPGGNFLWDY# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaagggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagaggcaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggaactttttatgggactactgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtccgtggaactcag +10335 JY8QFUQ01AJCO3 No results +10336 JY8QFUQ01C3IL3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10337 JY8QFUQ01CNEDV No results +10338 JY8QFUQ01C027H unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 670 93.42 142/152 nt 8 8 X 8.8.X [1.17.16.X] null - No rearrangement found ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaaaggccgattcaccatctccagagacaatg +10339 JY8QFUQ01CLZBQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARDILGATRFDYW in-frame - ctctggattcaccttcagcagctatgccatgagctgggtccgccaggctccagggaagggcctggagtgggtctcagctattagtggtattggtgggagtacattctacgcagactccgtgaagggccggttcaccatcaccagagacaattccaacaacacgctgtttctgcaaatgaatagcctgagagccgaggacacggccatatattactgtgcgagagatattctgggagctactcggtttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10340 JY8QFUQ01CGIC8 unknown (see comment) Homsap IGHV1-2*01 F, or Homsap IGHV1-2*02 F or Homsap IGHV1-2*04 F or Homsap IGHV1-2*05 F or Homsap IGHV1-46*01 F or Homsap IGHV1-46*03 F (see comment) 254 69.64 78/112 nt 8 8 X 8.8.X [0.17.4.X] null - No rearrangement found Low V-REGION identity (69,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcaccgaccactatctgcactgggtccgacaggcccctggacaagggcttgagtggatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +10341 JY8QFUQ01CL7VE productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 858 89.25 191/214 nt 88.79 190/214 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.16.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaaggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10342 JY8QFUQ01C97W1 productive Homsap IGHV3-30*01 F (see comment) 783 84.79 184/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [1.17.38.11] CARGDGYNFGGLDSW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcatcttcgatagttatgctctgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactctgtgaggggccgatccatcatttccagagacgattctaaaagaacactgtttctccaaatggacaacctgagagctgaggacacagctgtctattattgtgcgaggggagatggctacaatttcgggggattagactcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +10343 JY8QFUQ01A4C55 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 7 22 8.7.22 [1.17.38.11] CARVKTDYYDSSGSYLPLYFFDYW in-frame + tctctggtgactccttcagaactcactactggagttggattcgacagcccccggggaggagattggaatggattggcaatatatattatattgggaccaccaactacaacccctccctcaagagtcgagtcaccatgttagtggacacgtccaagaagcagttctccctgagactgagttctgtgaccgctgcggacacggccatgtattattgtgcgagggtcaagactgattattatgatagtagtggttcttacctgcccctgtatttctttgattactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgagctgcctggtcaaggactacttcccccgaaccggtgacggtgtcggtggaactca +10344 JY8QFUQ01CL4UJ productive (see comment) Homsap IGHV3-11*01 F (see comment) 687 80.37 172/214 nt 79.44 170/214 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-25*01 F 2 8 8 11 8.8.11 [1.17.37.11] CVRDRSRGIADPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 156 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 166 in the user submitted sequence), (cause frameshift) tctggattcaccttcactgactattggatgagttgggtgcgtctgaccccagggaagggtctagaatgggtttcgttcataagtggaagtggcaatagtgtctggtatgcagactctgtgaagggccgattcattatctccagagacaacgccaaaatttagtcttttggacatgaacagcctgagagtcgaggactcggccatgtattattgtgtgagagaccgcagcaggggaatagcagatccttggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10345 JY8QFUQ01CCRJF productive (see comment) Homsap IGHV3-11*01 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ6*02 F 263 94.83 55/58 nt Homsap IGHD1-26*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDYYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'GGG' (3 nucleotides at position 97 to 99 in the user submitted sequence), (do not cause frameshift); gcttctgggttctccttcagcgactacttcatgagttgggtccgccaggctccagggaagggactggagtgggttgcatacattagtagtagtggtGGGactactaaatactacgcagactctgtgaagggccgattcaccatctccagggacaacggcaagaattcattgtttctgcaaatggacagcctgagagtcgacgacacggccatgtatttctgtgtgagagactactattattacgggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +10346 JY8QFUQ01AJ2WR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 847 87.67 192/219 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD2-8*01 F 1 8 8 19 8.8.19 [2.17.38.11] CAKVFQVSGEHHFYYYGMNAW in-frame - gcctctggattcatctttagtaattatgccatgagttgggtccgccaggccccagggagggggctggagtgggtctcaactatcagtgccaatggagacaacacatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacagtgtatatgcaaatgaacagcctgaaagccgaggagacggccgtctatcattgtgcgaaagtcttccaggtgtctggcgaacatcacttctactactatggtatgaatgcctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10347 JY8QFUQ01A2WIH No results +10348 JY8QFUQ01BDGF0 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 937 92.24 202/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gcctctggatcaccctttggttattGatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10349 JY8QFUQ01A1MP0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 1 7 8 19 7.8.19 [2.17.38.11] CTKDYPDGRLLNQVRPFFDDW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) gcctctggatacagtttaacagttatgccatgacttgggtccgccaggctccagggaagggactggagtgggtctcaagtattatcgctaatggtggtgacacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagatgaacagccttagaggcgaggacacggccgtatattattgtacgaaagactatccggacggccgcttgttgaatcaggtgcgccccttctttgacgactgggaccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10350 JY8QFUQ01A287O productive Homsap IGHV3-13*01 F 976 94.91 205/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame - gcctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10351 JY8QFUQ01CYR1Z productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 890 90.7 195/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 7 14 8.7.14 [1.17.38.11] CATDDSNGWDEVADYW in-frame + cctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatatcagtggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10352 JY8QFUQ01BG6BT unproductive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CATSPVSSVTTGEGR#YW out-of-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctcccccgtttcatcggtgactactggggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccagcatggagacgtggtcgtcgcatgcctggtccagggcttcttccccca +10353 JY8QFUQ01CEGMR unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1095 100.0 220/220 nt 99.09 218/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 1 8 10 X 8.10.X [0.16.38.11] CTKCSVTIYL#FDYW out-of-frame - stop codons in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) ctggattcacctttGggtgattatgctatgagctggttccgccaggctccaggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttaccttttttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10354 JY8QFUQ01CHJER productive Homsap IGHV3-9*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + ctctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10355 JY8QFUQ01AYQK1 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10356 JY8QFUQ01CR8FR No results +10357 JY8QFUQ01CV3S6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10358 JY8QFUQ01BCLNK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10359 JY8QFUQ01AHDAC unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10360 JY8QFUQ01CJAF2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 8 8 9 8.8.9 [1.17.38.11] CAKEEVPNDYW in-frame - ctctggattcacctttagcaatgctgccatgacgtgggtccgccaggctccagggaaggggctagagtgggtctcaggtattagtattagtggtgatagaacatattacgcagactccgtgaagggccggttcaccatctctagagacaattccaagaataccgtgtatctgcaaatgaacagcctgagagccgaggacacggccatatattattgtgcgaaagaggaggtcccgaatgattattggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10361 JY8QFUQ01ASTX9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - ctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10362 JY8QFUQ01AX2K6 No results +10363 JY8QFUQ01AJ17C productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10364 JY8QFUQ01B4ODW productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 825 86.36 190/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARRHYGEGLFDYW in-frame + ctttggtggctccatcaccaataataattacttctggggctggatccgccagcccccagggaaggggctggagtggattggggatgtccagtatagtgggagcacctactccagtccgtccctcaagaggcgggtcaccatgtctgtggacgtgtccaaaagtcaggtctccctgagactgagctctgtgaccgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10365 JY8QFUQ01BKPFE unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKN*GVGDG##WYFDFW out-of-frame + stop codons in CDR2-IMGT at codon 58 of V-REGION: 'ATG' (3 nucleotides at position 87 to 89 in the user submitted sequence), (do not cause frameshift); ctctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattactaATGgtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttatttctgtgcgaaaaattagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10366 JY8QFUQ01DT2D1 productive (see comment) Homsap IGHV4-4*08 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 7 15 8.7.15 [1.16.38.11] CARGDGSLNSYGSLGNW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagtagttcctactggagctggatccggcagccgccgggaagggactggagtggattgggcatgtctataccagtgggagcaccgactacaacccctccctccggagtcgagtcaccatatcagtggacacgtcaaagaaccagttctccctgaagctgacctctgtgaccgccgcagagacggccttatattactgtgcgagaggggacgggagtttgaactcctacgggagtcttggcaactggggccagggaaccctggtcaccgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10367 JY8QFUQ01BS2Q3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 112 64.52 40/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame + ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10368 JY8QFUQ01AGYKQ unproductive Homsap IGHV3-48*04 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CSRHGGYTKLYNQM#YLDYW out-of-frame + cctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaactctagaaactcgctgtgtctgcaaatggacagcctgagagccgaggacacggctgtgtattactgttcgagacatggaggttacacgaaactctacaatcaaatgtctaccttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +10369 JY8QFUQ01AX3JG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKRLQAVADDAFDFW in-frame - cctctggattcatctttagtagctatgccatgggctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgagcagcctgagagccgaagacacggccatatattactgtgcgaaaaggttgcaagcagtggctgatgatgcttttgatttctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10370 JY8QFUQ01AQS6C unproductive Homsap IGHV3-11*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDLVGSIG#W out-of-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10371 JY8QFUQ01BWT8S No results +10372 JY8QFUQ01BRDXB productive Homsap IGHV3-48*01 F 923 91.74 200/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTRQTGNYYYFGVDVW in-frame - cctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10373 JY8QFUQ01DIQXW No results +10374 JY8QFUQ01CRJQG productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 968 92.07 209/227 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 3 10 9 19 10.9.19 [1.17.38.11] CARSSRRDRLSDRNYYELDFW in-frame - tctccggggacagtgtctctagcaacagtgccacttggaactggatcaggcagtccccaacgggaggccttgagtggctgggaaggacatactacaggtccaaatgggatactgattatgcggcgtctgtgaaaagtcgaataaccctcaccccagacacatccaagaaccagttctccctgcaattgaactccgttagtcccgaggacacggctgtgtattattgtgcaagatcttccagacgcgatcgtttgtctgataggaactactatgagctggacttctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10375 JY8QFUQ01CNGWQ productive (see comment) Homsap IGHV3-11*01 F 984 95.79 205/214 nt 94.86 203/214 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD1-1*01 F 3 8 8 13 8.8.13 [1.17.37.11] CARVNTWNADYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 66 of V-REGION: 3 nucleotides (from position 104 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcagtgactactacatgatctggatccgccaggctccagggaaggggctggagtGgggtttcatacattactagtcgtggtactatcatgtacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggccatttattactgtgcgagagtgaacacatggaacgccgactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10376 JY8QFUQ01B65GE No results +10377 JY8QFUQ01B49LV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10378 JY8QFUQ01BU1EN productive (see comment) Homsap IGHV3-7*02 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) tctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +10379 JY8QFUQ01AN6Q8 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 921 90.58 202/223 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD2-21*01 F 2 8 10 8 8.10.8 [1.17.38.11] CTSNSWLDRW in-frame - ctctggattctctttcagtaatgcctggatgaattgggtccgccaggctccagggaaggggctggaatgggttggccatattaaaagggaaattgatggtgggataacaaactacgctgcacccgtgaagggcagattctccatcgcaagagatgattcaaagaatatgatgtatttgcaaatgaacagcctgaacaccgaggacacaggcgtgtattactgtacctcaaattcgtggctcgaccgctggggccagggaacccccgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10380 JY8QFUQ01B7N1M unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 113 50.46 110/218 nt 50.0 109/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); tatttggattcaagtttagtaggtaGtgggatgaggtgggtccgccaggctccagggaaggggctggagtgggtggccgacgtactctatgttacgactgtggatctctgtgcgagaagtagcagttggttttacctgatatttcgcggaactacgatttgggcgtctggggccaagggactccggccaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10381 JY8QFUQ01CTMXD No results +10382 JY8QFUQ01DFUVA productive Homsap IGHV4-61*02 F 870 88.64 195/220 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + ctctggtggccccatcagcagcagcacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +10383 JY8QFUQ01C55RD unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 746 82.79 178/215 nt 8 8 X 8.8.X [0.17.38.X] null - No rearrangement found Low V-REGION identity (82,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10384 JY8QFUQ01DKDMJ unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +10385 JY8QFUQ01AWDNT No results +10386 JY8QFUQ01DBUXH productive Homsap IGHV3-11*03 F, or Homsap IGHV3-11*05 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*03 F or Homsap IGHV3-69-1*02 P or Homsap IGHV3-7*03 F or Homsap IGHV3-71*01 P 165 68.35 54/79 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 X X 19 X.X.19 [X.X.26.11] CATDGVGSTVKLMVMGPFDFR in-frame - ctctggattcgtctttaacaactatgccatgggctggatgaacagcctgagagccgaggacacggccgtttattactgtgcgacagatggagtagggtctactgtgaagttgatggttatgggcccttttgacttcaggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10387 JY8QFUQ01CHGTF unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 X 8.7.X [1.17.38.11] CAKTTMTSVT#DWFDPW out-of-frame + in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); ctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactgggggcaccgactccaaccCcctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgccctgcctgggtccaggggcttcttcccccag +10388 JY8QFUQ01CJOZ9 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt 97.24 211/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10389 JY8QFUQ01BBYYE unknown (see comment) Homsap IGHV3-7*03 F (see comment) 756 82.95 180/217 nt 82.49 179/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggcGtggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10390 JY8QFUQ01CF1BE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-10*02 F 2 8 8 13 8.8.13 [1.17.38.11] CAKERDNNVLPVDSW in-frame - Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcagcttcaatagttatactttgagttgggtccgccaggctccagggaaggggctggagtgggtctcagctatcagtggaacaggtgaaacaaccttctacgcggactccgtgaggggccggttcaccgtctccagagacaatttcaagaatactctgtacttgcaattgagcgacctgagagccgaagacacggccgtctattactgtgcgaaggagagagataacaatgttctgcccgttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggcgttctttccccca +10391 JY8QFUQ01DRV57 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASDLGGQKSYW in-frame + gtctggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10392 JY8QFUQ01BDYMQ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 757 82.65 181/219 nt 81.74 179/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 10 8.8.10 [2.16.38.11] CAKDDSAGLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 67 of V-REGION: 'T' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) agcctccggattcatcttcagtgccgcttggatggagtgggtccgccaagttccagggcagggctcgtgtgggtcgcgcgtatcgagagtagtggcagcggcacacgttTacgcggactacgtgaagggccgattcaccgtctccagagacaacgccatgaacatagtgtatcttcaaatgaattctctgactgccgaggacacgggtgtgtattactgcgcaaaggatgattcggccggccttgaccattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10393 JY8QFUQ01DQWIK No results +10394 JY8QFUQ01DRVNJ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 927 92.17 200/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift) cctctggattcaccCtttggttattatggcatgactgggtccgccaagctccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10395 JY8QFUQ01A7A9E productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - ctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctttatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10396 JY8QFUQ01AH5MI productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F (see comment) 669 79.44 170/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-10*01 F 2 8 8 21 8.8.21 [0.17.38.11] CARERRPGGYPNGYHHFYGMDVW in-frame + Low V-REGION identity (79,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgatacaattagtcgttatggcatgcactgggtccgccaggctccaggcaaggggctggagtggctggcaattatttcatatgatggaaataggatatatgttggagactccgtgaagggccgcttcaccgtttccagagacaacgccgggaggactctgtttctgcaaatgaacagtctgagaggtgatgacaccgccacatatttttgtgcgagagagcggcgtccgggtggctatccaaatggctaccaccatttttacggcatggacgtctggggccaagggaccagggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10397 JY8QFUQ01BF80N productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 738 82.49 179/217 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10398 JY8QFUQ01CB8PZ unproductive (see comment) Homsap IGHV4-61*01 F 942 92.27 203/220 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD6-6*01 F 2 10 7 X 10.7.X [1.17.38.11] CTRGAVHL*QPV# out-of-frame + stop codons ctctggtggctccatcagcggtagtactaactactggagctggattcggcagcccccagggaagggactggaattcattgggtatatctattccagtgggaggaccaactacaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccagttctccctgaggctggcgtctgtgaccgctgcggacacggccgtgtattactgtacgaggggggcagtacacttatgacagcccgtggggacaggggacccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10399 JY8QFUQ01BTJGP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggngccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10400 JY8QFUQ01CCU9E unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10401 JY8QFUQ01B756E No results +10402 JY8QFUQ01BJG4M productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt 99.54 216/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.16.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10403 JY8QFUQ01C7QLL productive Homsap IGHV3-11*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame - cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10404 JY8QFUQ01DLIBX unproductive Homsap IGHV3-9*01 F 887 89.91 196/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD2-21*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDGDSGWDYY#HW out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgacactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10405 JY8QFUQ01BRKFS productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 963 92.04 208/226 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 3 10 9 19 10.9.19 [1.17.38.11] CARSSRRDRLSDRNYYELDFW in-frame - ctccggggacagtgtctctagcaacagtgccacttggaactggatcaggcagtccccaacgggaggccttgagtggctgggaaggacatactacaggtccaaatgggatactgattatgcggcgtctgtgaaaagtcgaataaccctcaccccagacacatccaagaaccagttctccctgcaattgaactccgttagtcccgaggacacggctgtgtattattgtgcaagatcttccagacgcgatcgtttgtctgataggaactactatgagctggacttctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10406 JY8QFUQ01BOU6G productive Homsap IGHV4-34*10 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame + tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10407 JY8QFUQ01DJL36 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDFFIGGYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +10408 JY8QFUQ01AH02C productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10409 JY8QFUQ01AF6EZ productive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10410 JY8QFUQ01CBFGR productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10411 JY8QFUQ01CAAF5 productive Homsap IGHV3-21*04 F (see comment) 647 78.14 168/215 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [0.17.38.11] CVRLFTSDGVRGDYW in-frame + Low V-REGION identity (78,14% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ccggtttcatcttcagtcacttcagcatgaactgggtccgccaggctccaggaaagggcctggagtggatcgccgacatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcgacgatacggccacctattattgtgtgaggctcttcaccagcgatggagtgagaggcgactactggggccagggcgcccgggttctcgtctccgcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10412 JY8QFUQ01BGSKW No results +10413 JY8QFUQ01BQ3IH unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 878 89.45 195/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found gttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactantgggggcgaggggaaccctgattttccgnctccctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10414 JY8QFUQ01AE5XE productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARVRGYYGGQYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +10415 JY8QFUQ01AQAEH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGSYLYSFDYW in-frame + ctctgggttcacctttgcccactttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtggtgatgattccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactcctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +10416 JY8QFUQ01BMOB5 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +10417 JY8QFUQ01BJMI5 productive Homsap IGHV1-2*02 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARVWGTGVGYLDYW in-frame + tggatacaccttcaccgcctactatatacactgggtgcgacaggcccctggacaaggacttgaatggatgggattgatgaaccctaatagtggtggcacaatatacgcgcagaagtttcagggcagggtcaccatgaccagggacacgtccgtcgacacagcctacatggagttgagcaggctcaaatctgacgacacggccatttattattgtgcgagagtctggggtacgggagtcggctaccttgactactggggccagggaacccgggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10418 JY8QFUQ01BDDDQ No results +10419 JY8QFUQ01CR6PP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKRLQAVADDAFDFW in-frame + ctctggattcatctttagtagctatgccatgggctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgagcagcctgagagccgaagacacggccatatattactgtgcgaaaaggttgcaagcagtggctgatgatgcttttgatttctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10420 JY8QFUQ01CDV3C productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt 99.08 215/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.16.38.11] CARDFFIGGYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccGttcagtagctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10421 JY8QFUQ01DDTVS unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt 99.53 214/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons in FR3-IMGT at codon 101 of V-REGION: 'C' (1 nucleotides at position 204 to 204 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccCgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc +10422 JY8QFUQ01DC4V0 No results +10423 JY8QFUQ01CEZMT productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 806 85.78 187/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 8 13 8.8.13 [1.17.38.11] CATYGRFSFSPLDYW in-frame + cgtctggattcgacttcagtagttatggcttccattgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctccccttgactactggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10424 JY8QFUQ01BFZEE productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 836 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.37.11] CAGSGRDPYGINVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaattcctatnccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10425 JY8QFUQ01BPYPO productive Homsap IGHV3-11*01 F 846 88.02 191/217 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CADIKLGDWCFDLW in-frame - ctctgaaatcaccttcagcgaccactacatgagctggatccgccaggctccaggaaaggggctggaatggatttcatatattagcaccagtggtaatatgatctattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaggtcgatgtatttgcagatgaacagtctgagagccgaggacacggccgtctatttctgtgccgatataaaactgggtgactggtgcttcgatctctggggccgtggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10426 JY8QFUQ01BFTGY productive (see comment) Homsap IGHV4-59*03 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 89 to 94 in the user submitted sequence), (do not cause frameshift); ctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10427 JY8QFUQ01ADBWF No results +10428 JY8QFUQ01AHOM5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 776 83.71 185/221 nt 83.26 184/221 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift); aatgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGgggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10429 JY8QFUQ01BTFSH No results +10430 JY8QFUQ01DF0WH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 960 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDRGCTNGACYVADFW in-frame - ggcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10431 JY8QFUQ01BLA2V productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 869 88.99 194/218 nt 88.07 192/218 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [2.16.38.11] CARDSGSSDYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) gcctctggattcagGttttagttcttatggcatgaactgggtccgccaggctccatgggggggctggagtgggtctcattcattaacagtgttagtagttacaaatactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaagaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagatagcggctcgtccgactacactaggtacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10432 JY8QFUQ01AO0RN No results +10433 JY8QFUQ01ALQU4 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +10434 JY8QFUQ01DGLOZ No results +10435 JY8QFUQ01CJ5D5 No results +10436 JY8QFUQ01AKZ0I productive (see comment) Homsap IGHV4-39*03 F 937 92.2 201/218 nt 91.28 199/218 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 9 6 17 9.6.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 26 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) tctccggtggctccatcaacagtagaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10437 JY8QFUQ01CJ990 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.16.38.11] CARDTLEVVSNMDDAFDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10438 JY8QFUQ01DIRRZ productive Homsap IGHV4-34*03 F (see comment) 750 83.57 178/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [1.17.38.11] CTRGRLDAWEVSDHW in-frame + Low V-REGION identity (83,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgacgatgggtcctgtagagagtgcttctggagttggatccgccagtccccagggaagggtctggagtggattggggacgtcaattatagacgaggcgtcgactacaacccgtccctcaagagtcgagtgaccatatcattggacacgtccaacaaacaagtctccctgagtctgagttctgtcaccgccgcggacacggccatgtattattgtacgcgagggcgattagacgcgtgggaagtatcggaccactggggccagggaaccgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +10439 JY8QFUQ01COD4T productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttcccccaa +10440 JY8QFUQ01BWHU4 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1072 96.93 221/228 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [2.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - atctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagatgctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10441 JY8QFUQ01AWLUJ unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 934 91.44 203/222 nt 90.99 202/222 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD3-22*01 F 3 8 9 X 8.9.X [1.17.38.11] CATDRPYYKNAAGRLWYYYGMDV#W out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatgggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaacgctgctggccgactctggtattactacggtatggacgttttggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10442 JY8QFUQ01BO5QJ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 7 8 15 7.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc +10443 JY8QFUQ01DDY8Y productive Homsap IGHV4-61*02 F 857 87.78 194/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 11 10.7.11 [1.17.38.11] CARSGWDNQFDFW in-frame - tctctggtgtcgccaccagtagtggcacttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaacccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10444 JY8QFUQ01CZQKG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKIDSRNYDFWSGYYAHW in-frame - cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtttattactgcgcgaaaatagatagtcggaattacgatttttggagtggttattatgcacactggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10445 JY8QFUQ01BLZXE productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10446 JY8QFUQ01CI9HQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame + ctctggattcagtttcagagactatgccatgagttgggtccgccaggctccagggaagggactggagtgggtctcagcaattagtggaactggtcttaccacatattacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggaccagggagccctggtctccgtctcctcagcatccccgaccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +10447 JY8QFUQ01DDYTC productive (see comment) Homsap IGHV3-7*01 F 824 86.7 189/218 nt 86.24 188/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CGRDERGADLPNDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 91 of V-REGION: 'CT' (2 nucleotides at position 178 to 179 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagaCTgaaacagcctgagccccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctggggcctgggaaccctggtcaccgtctccgtcaccatccctgacccagccccaaggtcttccgctgcagctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10448 JY8QFUQ01CHRC3 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 855 88.48 192/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame + ttctggattcagtcctaccgatttttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggctcaaggactacttcccccgaaccggtgacggtgtcgtggaactcagg +10449 JY8QFUQ01BTRS8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcaaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10450 JY8QFUQ01B8D1W productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 782 85.12 183/215 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CATVRHLGERIFDFW in-frame - tctctggggccaccatgagtagtttctactggagctgggttcggcagtccccagggaggggactggagtggattggatttgtttcttacagtgggcccaccaactacagcccctccctcaagagtcgagtcaacttatcactggacgcggccaacaaacagttctctttgcagctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10451 JY8QFUQ01AH46J productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFV in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttcgtgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10452 JY8QFUQ01BHTRG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10453 JY8QFUQ01AXNDN No results +10454 JY8QFUQ01DAWZK productive (see comment) Homsap IGHV3-7*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [2.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) gcctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10455 JY8QFUQ01BZ6M2 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + cgtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +10456 JY8QFUQ01C8ROP productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1007 96.74 208/215 nt 95.81 206/215 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [0.17.38.11] CARDGTSSPEPNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); ctggattcaGccttcagtaactatgacatacactgggtccgccaggctccaggcaAaggggctggagtgggtggcagttatatggtatgatggaagtaataaatactatgcagagtccgtgaagggccgattcgccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcttgagagtcgaggacacggctgtgtattactgtgcgagagatggaaccagctcgccggagcccaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10457 JY8QFUQ01CUW9U productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-7*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDRNYAFDYW in-frame + ctctggattcaccttcagcagctttagtatgaactgggtccgccaggctccagggaagggactggagtggctttcatacattagtaatactggtagtaacaaatactacgcagactctgtgaagggccgattcaccatctccagagacgatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgtgcgagagatcggaactacgctttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10458 JY8QFUQ01BONLS unproductive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CVKGRGYNDYGLDY## out-of-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggccccgggaaccctgctcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10459 JY8QFUQ01AD0NK No results +10460 JY8QFUQ01A2QEG productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-3*02 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGPGGGWYAEQW in-frame + gtctggattcagtttcagtgactatgccatgcactgggtccgccagactccaggcaaggggctggagtgggtggcagttatttcatatgatgggagagagaagtactatgcagactccctgaagggccgattcaccacctccagagacaactccaagaaaatgctgtatctccaagtgaatagcctgagacctggagacacggctgtgtattactgtgcgaaagatgggccggggggtggctggtacgctgagcagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10461 JY8QFUQ01BIS54 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaaggacccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10462 JY8QFUQ01DOC2V unknown (see comment) Homsap IGHV4-61*02 F (see comment) 702 80.65 175/217 nt 80.18 174/217 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); ctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggGggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgccctttgtacacaccgcccgtcgctactaccgattggatggtttagtgaggccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10463 JY8QFUQ01A4KC1 unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*03 F 820 86.3 189/219 nt Homsap IGHJ5*01 F (see comment) 120 70.59 36/51 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [2.17.38.11] CARDQRDYDYIYYYGMD#SG out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) gcctctggattctccctcaggaatcatgctatgcactgggtccgccagactccaggcaagggactcgagtgggtggcagttatctcatttaatggacgaaggaagtattatgcagacttcgtgaagggccgattcaccatcaccagggacaattcccagaacactctgtctctgcaattgaatagcctgggaactgaggacacggctgtctattactgtgcgagagatcagcgtgactacgattacatctactattacgggatggacctctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10464 JY8QFUQ01BI8GQ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 920 90.95 201/221 nt 90.5 200/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-8*02 F 1 10 7 12 10.7.12 [1.17.38.11] CARLTDWWGHFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcggtacttctcattactGggggctgggtccgccagcccccagggaaggggctggagtggattggcagtatctactctggtgggaccacctactacaacccgtccctcaagagtcgactcaccatgtccgtcgacacgtccaagaaccagatgtccctgcggctgagctctgtgaccgccgcagacacggctgtctattactgtgcgagactgacagactggtgggggcactttgatcactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10465 JY8QFUQ01B5TP7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [2.17.38.11] CTREVGATDYW in-frame - gcctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +10466 JY8QFUQ01AKX3F productive Homsap IGHV4-4*07 F 590 86.54 135/156 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 X 7 15 X.7.15 [X.7.38.11] CARQRGGGDRQWAFENW in-frame - ggactggagtggattgggcgnatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccacccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10467 JY8QFUQ01AYMY9 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +10468 JY8QFUQ01BF9OL unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt +10469 JY8QFUQ01CT3WE No results +10470 JY8QFUQ01AC0IS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10471 JY8QFUQ01ALRD3 unproductive Homsap IGHV3-48*02 F 971 94.88 204/215 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [0.17.38.11] CARPAGEGDPFS#YYSGLDVW out-of-frame - ctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgaccctttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10472 JY8QFUQ01BHBI8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10473 JY8QFUQ01BPIYL productive Homsap IGHV1-24*01 F 993 96.26 206/214 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [0.17.38.11] CAIGAMATW in-frame - cggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10474 JY8QFUQ01DHOH7 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1003 98.55 204/207 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-17*01 F 2 6 8 16 6.8.16 [X.17.38.11] CARQLDYGDYSRHGLDVW in-frame + aactttaccggctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccgtgtattactgtgcgagacaattagactacggtgactactctaggcacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +10475 JY8QFUQ01B0FPZ productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10476 JY8QFUQ01ARP0R unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 109 50.24 105/209 nt 8 8 X 8.8.X [1.17.35.X] null + No rearrangement found ttctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10477 JY8QFUQ01DWT8O unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 856 88.13 193/219 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [2.17.38.11] CANEVGYCSSG# out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccagggaaggggctggagtgggtctcaactattcgtgcccgtggtgataggacacactacgcggactccgtgaagggccgcttcaccatctctagagacaattcaaaggacaccctgtatttgcaaatgtacagcctgcgagtcgaggacacggccgtctattactgtgcgaacgaagtcgggtactgtagtagtgggggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10478 JY8QFUQ01AMN4Y unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 751 82.87 179/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (82,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10479 JY8QFUQ01B8RZ5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10480 JY8QFUQ01B4LFK productive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 930 91.03 203/223 nt Homsap IGHJ6*01 F (see comment) 180 76.19 48/63 nt Homsap IGHD4-11*01 ORF 3 8 10 18 8.10.18 [1.17.38.11] CVRHEGTPVSDVGGYGMDVW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) ctctggggtcaccttcagtgacgcctggatgacctgggtccgccaggtttccgggaaagggctggagtgggttggccgtattagaagcaaagcttacaattccgcgacagcatatgctgcgtcggtgaaaggcaggttcaccatctccagagatgattcaaagaacacggcgtatttggaaatgaacagtttgaagagggaggacacggccgtgtattactgtgtgagacatgaagggactccagtaagtgatgtaggtggatacggcatggacgtctggggtcaagggtccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +10481 JY8QFUQ01CMYZK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10482 JY8QFUQ01AS4RT No results +10483 JY8QFUQ01BZK7M unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F (see comment) 765 83.41 181/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagaagttatggcatgcactgggtccgccgggctccaggcaaggggctggagtgggtggcacttgtgtcatatgatggaagtcataaatattatacagactccgtgacgggccgattcaccatctccagagacaattccaaaaatatgttgtatctacaaatcgacagcctgagagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10484 JY8QFUQ01A2GOZ unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 826 87.79 187/213 nt 87.32 186/213 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.37.11] CARENGSGPPQH#DVW out-of-frame + in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 187 in the user submitted sequence), (cause frameshift) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagcccgaggacacggccgtctactactgtgcgagagaaaatggttcgggccccccacagcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10485 JY8QFUQ01AERH9 productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaacctcagg +10486 JY8QFUQ01ASO9V productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcanttcccccgaaccggtgacggtgtgcgtggaactcag +10487 JY8QFUQ01AVBNC productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt 88.69 196/221 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD5-24*01 ORF 3 10 7 15 10.7.15 [1.17.38.11] CARRTGSDGFREGFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagtactggttattactgggcctggatccgccagcccccaggaaAagggcctggagtggattggaagtatccataagcttgggaacacctataacaacccgtccctcaagagtcgagccaccatctccgtggacaagtccaagaaccagttctccctgaggctgaggtctgtgaccgccgcagacacgggtgtgtattattgtgcgagacgaacaggcagcgatggcttcagagagggtttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10488 JY8QFUQ01AVHXS No results +10489 JY8QFUQ01DEDXM unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 674 94.04 142/151 nt 8 8 X 8.8.X [1.17.16.X] null + No rearrangement found ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaat +10490 JY8QFUQ01DAV7M productive (see comment) Homsap IGHV3-33*03 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10491 JY8QFUQ01A5O1J productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [2.16.38.11] CATSRGSANWYPFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gcctctggattcaatttcagtaattacaccatgaactgggtccgccagcctccaggaagaggctggagtgggtcgcatccattaatgttggcactacttatatatattacggagacgcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10492 JY8QFUQ01BRUOX No results +10493 JY8QFUQ01C9VCP No results +10494 JY8QFUQ01CXTJW productive Homsap IGHV3-48*02 F 973 94.06 206/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAKDRGGSAYPIFDYW in-frame - gcctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaatagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10495 JY8QFUQ01BJQPU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.02 191/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-21*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKIDPNTNWPTDFW in-frame - ctctggattcacctttagcagctttggcatgaactgggtccgccaggctccagggaagggcctggagtgggtctcagcaataggtcgtgctgtcactagcacatattacgcagcctccgtgaagggccggttcaccatctccaaagacaattccaggaacacggtatatctgcaaatgaacagtttgagagccgacgacacggccttatatttctgcgcgaagattgatcccaataccaattggcctactgacttttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10496 JY8QFUQ01A4M9B productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 883 89.5 196/219 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-3*01 F 3 8 8 17 8.8.17 [2.17.38.11] CARILTLFAVVTSSGMDVW in-frame - Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) gcctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccatcaccagtagtggtagttatgtctaccattcagactcaacgaagggccgattcaccatctccagagacaacgcccagaattcactatttctgcaaatgaacaacctgagacccgaggacacggctatatattactgtgcgaggatcctgacgctttttgcagtggttacctccagtgggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10497 JY8QFUQ01CQCGP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10498 JY8QFUQ01AKMHL No results +10499 JY8QFUQ01AWP6D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVKDISRSGCFEYW in-frame + ctctggattccagtttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtccatcgcctgcctggtccagggcttcttccccc +10500 JY8QFUQ01AZ1TU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 790 85.92 183/213 nt 85.45 182/213 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-13*01 F 1 8 7 16 8.7.16 [1.17.38.11] CAKTQPFGTTWYGATDAW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 82 in the user submitted sequence), (do not cause frameshift) ctctggtttacctttagcaactttgccatggcttgggtccgccaggctccaagaaaggggctggagtgggtctcagctattgctcgtggcggtgacacacactaccgagactccgtgaagggccgattcaccatctccagagacaattctaagaacacactgattctgcagatgagcagcctaagagccgaggacacggccttatattactgtgcaaagacgcagccgtttggcaccacctggtacggtgctacggatgcgtggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10501 JY8QFUQ01BEJEJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10502 JY8QFUQ01B8W3M productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKKYHYGSGSYLYCFDYW in-frame - gcctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtggtgatgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactgctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10503 JY8QFUQ01A1UXL productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 896 90.37 197/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 8 8 20 8.8.20 [1.17.38.11] CTRTQFDPDYGDYETGYGMDVW in-frame + cggctggattcaacttccgatcttatgccatgtactgggtccgccaggccccaggcaaggggctggactgggtggcagttatttggcatgatggcagtaatcaatactatgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacattgtttctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtacgaggacgcaatttgaccctgactacggtgactacgagacggggtacggtatggacgtctggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10504 JY8QFUQ01C835G No results +10505 JY8QFUQ01BLOLV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDQSCIVGPCGFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10506 JY8QFUQ01CVAJT productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-8*02 F 1 10 7 12 10.7.12 [0.17.38.11] CARLTDWWGHFDHW in-frame - tggtggctccatcagcggtacttctcattactggggctgggtccgccagcccccagggaaggggctggagtggattggcagtatctactctggtgggaccacctactacaacccgtccctcaagagtcgactcaccatgtccgtcgacacgtccaagaaccagatgtccctgcggctgagctctgtgaccgccgcagacacggctgtctattactgtgcgagactgacagactggtgggggcactttgatcactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10507 JY8QFUQ01A39P0 No results +10508 JY8QFUQ01AKOZR No results +10509 JY8QFUQ01AQTUT unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 558 72.81 158/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (72,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctagattcatctttagtagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactatcagtggtagtggtgataacacatactacgcagactccgtgaagggccggttcaccatctccagagacaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10510 JY8QFUQ01DHHV8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10511 JY8QFUQ01BKBNG productive Homsap IGHV3-11*01 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKVGSMNIEASPPDDW in-frame - gcctcgggttcagcgtcagtaataacttcatgacctgggtccgccaggctccggggaaggggctggagtgggtctcatatattagtagtagtggtaggaccatctactacgctgactccgtgaagggccgattcaccatgtccagagacaatgccaagaattcactgtatctacaaatgaacagcctgagagccgaggacacggccgtctattactgtgcgaaagttggcagcatgaatatcgaggcgagccctcctgacgactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacatggtcatcgcctgcctggtccagggcttcttccccca +10512 JY8QFUQ01B7H46 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctCcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10513 JY8QFUQ01AW0AD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10514 JY8QFUQ01DEK7Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 787 85.19 184/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD2-21*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARRSGRDGGWFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcatctttgccgactatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtcgcagatattaatggaagaggtgctgccgcacactacgcagactccgtgacgggccgcttcaccctctacaaagacggttccaagaatacgatgtatctgcaaatgaggaccctgagagacgacgacacggccaaatattactgtgcgagacgaagtgggcgtgatgggggctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +10515 JY8QFUQ01C67L4 No results +10516 JY8QFUQ01BBPXX productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame - tctctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10517 JY8QFUQ01CBXMD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.16.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10518 JY8QFUQ01C7A0D productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame + gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10519 JY8QFUQ01A7FE0 productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10520 JY8QFUQ01BQAON productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F 815 86.24 188/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARPHHNSGYSFDHW in-frame + cgtctgatttcaacgtcggtgactttgacatgcactgggtccgccagactccagacaaggggctggagtgggtggcacttttttggtatgacggaaagaggaaatattatgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacaccctgtatctgcaaatggacagcctgagagccgacgacacggctacctacttttgtgcgaggcctcatcataatagtggttattcctttgaccactggggccagggaacccaggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatcgcctggtcaggcttcttcccccga +10521 JY8QFUQ01BSNGL No results +10522 JY8QFUQ01B91QK No results +10523 JY8QFUQ01AQ7NM productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10524 JY8QFUQ01ADN6X No results +10525 JY8QFUQ01DB7WG No results +10526 JY8QFUQ01AIM1I productive Homsap IGHV3-11*04 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame - cctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtacctgcaaatggacagcctgaggcctgaagacacggctgtatattactgtgccagagatgagctcccttgggatacaatagagtactactttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10527 JY8QFUQ01AQP2P unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 99 52.59 71/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10528 JY8QFUQ01BOHHB unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc +10529 JY8QFUQ01AHCLR productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10530 JY8QFUQ01BTS32 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10531 JY8QFUQ01A1J79 No results +10532 JY8QFUQ01A4ONL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CIMDLVGRADYW in-frame + ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgagagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10533 JY8QFUQ01DBY4U unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 353 86.17 81/94 nt 8 5 X 8.5.X [1.17.X.X] null - No rearrangement found ctctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc +10534 JY8QFUQ01ALX54 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10535 JY8QFUQ01DRRVW productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 973 94.06 206/219 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [2.17.38.11] CAREVSDAFEMW in-frame - gcctctggattcacctttgatgattttggcatgagttgggtccgccaagttccagggaaggggctggagtgggtcgctggtatcagttggaatggaggcaaaacaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcattgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10536 JY8QFUQ01ACTFT No results +10537 JY8QFUQ01BQMV0 productive Homsap IGHV4-61*02 F (see comment) 686 79.19 175/221 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-9*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARERDRSIGGASELDSW in-frame + Low V-REGION identity (79,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctcttctgtccccataagcagtggtggttactattggaactggatccggcagcccgccgggaaggggctggagtggatcggacgtgttgacagtaatgggttcgtcaggtacaacagttccctcaagagtcgactttctatgtcggtggacatgtccaagagtcaggtctccctgaggttgaggtctgtgatcgccgcggacacggccgtatactattgtgcgcgagaacgcgataggtcgattggcggagcgtcagaacttgactcctggggccagggatctctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +10538 JY8QFUQ01AQ4WG No results +10539 JY8QFUQ01BZ42A No results +10540 JY8QFUQ01AMM1A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctaggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10541 JY8QFUQ01CXALF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 779 84.4 184/218 nt 83.94 183/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); gtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGgggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10542 JY8QFUQ01DMQOQ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 84 51.52 68/132 nt 8 8 X 8.8.X [2.17.9.X] null - No rearrangement found stop codons gcctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +10543 JY8QFUQ01CIOY1 productive (see comment) Homsap IGHV3-48*02 F 973 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 3 8 8 20 8.8.20 [2.17.38.11] CARARRTISGVVFIEHYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcaggacccatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcattcattagtagtagtagtggtaccataAttttatgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactttatctgcaaatgaacagcctgagagacgaggatgcggctgtgtattactgtgcgagagcccgtaggacgatttctggagtggtttttattgagcactacggtatggacgtctggggcccagggaccacggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10544 JY8QFUQ01CAESX No results +10545 JY8QFUQ01B61FL productive (see comment) Homsap IGHV3-7*01 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaAaagggccgattcaccactcccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10546 JY8QFUQ01DK87J productive Homsap IGHV4-4*07 F 953 93.95 202/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD4-17*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARDLLTVTTGALDIW in-frame + tttctggtggctccctcagtagttactactggaactggatccggaagcccgccggggagggactggagtggattgggcgtatttactacagtgggagcaccaattacaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccagttctccctaaagctgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagagatcttcttacggtgactactggggctcttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10547 JY8QFUQ01CXSE7 No results +10548 JY8QFUQ01BNHO0 No results +10549 JY8QFUQ01DC522 productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - tctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10550 JY8QFUQ01AMZ3Z productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [2.17.38.11] CARAYSGPGPYYFDYW in-frame - gcctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10551 JY8QFUQ01DMH5G unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1008 96.31 209/217 nt Homsap IGHJ4*03 F 69 60.42 29/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDTLEVVSNMDDAFDV# out-of-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaaggacaatggtcaccgtctctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10552 JY8QFUQ01BUB6H productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1008 96.31 209/217 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDVW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10553 JY8QFUQ01CI79S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10554 JY8QFUQ01BYIDH No results +10555 JY8QFUQ01BL3CK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10556 JY8QFUQ01B00WG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 978 94.09 207/220 nt 93.64 206/220 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [2.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); agcctctacattcGccctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10557 JY8QFUQ01AOTAE unproductive (see comment) Homsap IGHV4-61*02 F 925 90.99 202/222 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 X 10.7.X [2.17.38.11] CAREK**SV#NWFDPW out-of-frame - stop codons gtctctggtgactccatcaccagtggtaattattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggatcaccaactacaatccctccctcaagagtcgagtcaccatactattagacacgtccagcaaccggttctccctgaagctcagctctgtgaccgccgcagacacggccgtgtattactgtgcgagagaaaagtagtgatccgtcccaattggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10558 JY8QFUQ01BS6QJ No results +10559 JY8QFUQ01B2W9U No results +10560 JY8QFUQ01B4VTT productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARMGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagaatgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10561 JY8QFUQ01CCW4G productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYHFDYW in-frame - tctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10562 JY8QFUQ01B6XCF productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 880 90.61 193/213 nt 90.14 192/213 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [1.17.38.11] CTRELRVAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); tctggattcaccgtcagtaccaagGttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagtaatttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +10563 JY8QFUQ01A72FV productive Homsap IGHV3-11*01 F 948 93.93 201/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [0.17.38.11] CARDPHRGDGCTYDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggattcaccttcagtgactaccacatgggctggatccgccaggctccagggaaggggctggagtgcgtttcatacattagcactagtggtcgtgacatatacaacgcagactctgtgaagggccgattcaccatctccagggacaacgcccagaagtcactgtatctgcaaatgaacagcctgagagccgaggacacagccgtgtatttctgtgcgagggatccccatcgtggagatggctgcacttacgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10564 JY8QFUQ01AHL3I productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1080 97.79 221/226 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 9 11 10.9.11 [1.17.38.11] CARLDYTRYFDYW in-frame - ctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10565 JY8QFUQ01CYYZE No results +10566 JY8QFUQ01DOU9I productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +10567 JY8QFUQ01CN2IZ unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F (see comment) 436 66.98 144/215 nt 10 9 X 10.9.X [1.17.34.X] null - No rearrangement found Low V-REGION identity (66,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10568 JY8QFUQ01APU75 unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtaacggtgtcgtggaact +10569 JY8QFUQ01DRLUL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKGIVGDTFFDYW in-frame + cctctggattcacctttagtaattatgccctgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggaatcagtagtagtggtgagatcccaaactacgcagactccgtgaagggccggttcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaaagggatagtgggagacactttctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10570 JY8QFUQ01C3ZMO productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10571 JY8QFUQ01B8LLE productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10572 JY8QFUQ01CA1P8 No results +10573 JY8QFUQ01CXMQ6 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 927 92.17 200/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10574 JY8QFUQ01BJM6L productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +10575 JY8QFUQ01B0EEH productive (see comment) Homsap IGHV3-48*01 F (see comment) 763 84.11 180/214 nt 83.18 178/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaAagggnctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10576 JY8QFUQ01B9XTE No results +10577 JY8QFUQ01AEKIC No results +10578 JY8QFUQ01CF7J5 No results +10579 JY8QFUQ01BT63X unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKSPLSVAGTRQK#WFDPW out-of-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaagctggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagacctctgggggccacagcgcccttgggctgcctggtcaaggactacttccccgaccggtgacggtgtcgtggaactcag +10580 JY8QFUQ01BIDN9 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-16*02 F 1 8 8 X 8.8.X [1.17.38.11] CVRRGM*RAD#DAFDIW out-of-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttatagcatgaactgggtccgcctggCctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatgtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcgtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10581 JY8QFUQ01CXOHG unproductive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 824 86.7 189/218 nt 86.24 188/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-21*01 F 2 9 7 X 9.7.X [1.17.38.11] CTSREHALVVNSR#DYW out-of-frame - stop codons in CDR1-IMGT at codon 36 of V-REGION: 'GTC' (3 nucleotides at position 24 to 26 in the user submitted sequence), (do not cause frameshift); tgtctggtgtctccgtcaccagcGTCagtcactggtggacctgggtccgccagcccccagggaagggactggagtggattggagaaatctattattatggcatcaccaatttcaacccgtccctcaagagtcgaatcagcatgtcagtggacgagtccaagaaccagttctccctgagactgacttctgttaccgccgcggacacggccgtttattattgtacgagtcgcgaacatgctttagtggtcaattcacgggtgactactggggccagggaaccctgatgaccgtcacctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10582 JY8QFUQ01BZG0Q productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10583 JY8QFUQ01BFWQ9 productive Homsap IGHV3-48*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVRERGNSYGEIDYW in-frame - tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgnccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10584 JY8QFUQ01AVMHK productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); ctctggattcccttTttagaacctattggatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10585 JY8QFUQ01A45ND productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1002 96.73 207/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFYYW in-frame - tggatacaccttcaccagctactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagacttttactactggggccagggaaccctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10586 JY8QFUQ01B9JJT productive Homsap IGHV1-2*02 F 817 86.92 186/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame - tggatatactttcaccgaccattatgtttactggatgcgacaggcccctgganaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10587 JY8QFUQ01AOXYI unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD2-21*02 F 2 8 8 X 8.8.X [1.17.38.11] CARLPFIVVVTGAFFGTL*LL# out-of-frame + stop codons in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ttctggatacatctttaccaattactggctcggctgggtgcgccagatgcccggcaaaggcctggagtggatggGggatcatctttcctgctgactctgatgcccgatacagcccgtccttccaaggccaggtcaccatctcaatcgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacgccgccatatattactgtgcgagactcccctttattgtggtggtgactggtgcgttttttgggacactttgactattgggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10588 JY8QFUQ01CTGKM productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10589 JY8QFUQ01DQJQS productive (see comment) Homsap IGHV3-48*03 F 874 89.04 195/219 nt 88.58 194/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) agcctctggattcaccttcagttcttatgccatgaactgggtccgcctggtccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +10590 JY8QFUQ01C0BZ0 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame - tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10591 JY8QFUQ01BMWJ8 productive (see comment) Homsap IGHV4-39*02 F (see comment) 781 83.78 186/222 nt 82.43 183/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 9 7 22 9.7.22 [2.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'TAC' (3 nucleotides at position 30 to 32 in the user submitted sequence), (do not cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'CT' (2 nucleotides at position 32 to 33 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 2 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) ctgtctccggtgtctcccattagtagtgaTACTttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10592 JY8QFUQ01BI4Q0 No results +10593 JY8QFUQ01AD3OR No results +10594 JY8QFUQ01AGW41 No results +10595 JY8QFUQ01DIOHI productive Homsap IGHV4-4*07 F (see comment) 720 81.57 177/217 nt Homsap IGHJ4*03 F 195 89.58 43/48 nt Homsap IGHD3-3*02 F 3 10 7 16 10.7.16 [2.17.38.11] CARSGYTSIVGVREFDSW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01DIOHI ; 8 AA in Homsap_IGHV4-4*07), and low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggcgggcccccatgactgataaaaattactattggagttggatccggcagcccgccgggaagggactggagtggctcggacgtgtttatggtagcgggagcacaagctccaatccctccgtcaggagtcggatcaccatgtcaatatacacgtctatgaaccaattctccctgaggttgagttctgtgaccgccgcggacacggccgtctattattgtgcgagatcaggttatacttccattgtcggagtgagggagtttgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10596 JY8QFUQ01AZ6AK No results +10597 JY8QFUQ01B9VEW unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDNYGDYW# out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10598 JY8QFUQ01A4DNG unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-16*01 F 1 8 7 X 8.7.X [1.17.38.11] CARKGLVPSMFFFDF## out-of-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggcccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccttggcaccctcctccaagagcacctctggggggccacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10599 JY8QFUQ01DV8LF productive Homsap IGHV3-74*03 F 1031 97.25 212/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [1.17.38.11] CATGPDYAYAMW in-frame + cctctggattcaccttcagtcgctactggatgcactgggtccgccaagctccagggaagggcctggtgtgggtctcacgtattaaaagtgatgggattagcacaacgtacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtactactgtgcaaccgggcccgattatgcgtatgctatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggctccagggcttcttccccca +10600 JY8QFUQ01A7TRV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 8 17 8.8.17 [1.17.38.11] CAKDLVVTSIGPQGIHGHW in-frame + ctctgggttcacctttagcagctatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaagtatcagttttagtggtgagagaacatattatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacagtacatttgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaagatctggtggtgactagtattggcccccagggaatccatggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +10601 JY8QFUQ01CKBJQ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 864 88.48 192/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found gtctggattcaccttcagtagctatggcatacactgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagagccgaggccctgccgctggccttcacacagaagaccatcgaccgcttggcgggt +10602 JY8QFUQ01BJO34 unproductive Homsap IGHV3-48*01 F 815 86.24 188/218 nt Homsap IGHJ4*03 F (see comment) 114 70.83 34/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRGAGLDV## out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaggggctggagtgtgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctggacgtctgggggccaagggaccacggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +10603 JY8QFUQ01BZ3T1 productive (see comment) Homsap IGHV2-5*02 F 1071 93.44 228/244 nt 93.03 227/244 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 3 10 7 13 10.7.13 [9.17.38.11] CAHRRVGTATAFDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttctctgggttctcactcagtaacagtggagtgggtgtgggctgggtccgtcagcccccaggaaaggccctggagtggcttggacacaCttttttgggatgatgataagcgctacagtccctctctgaaaagcaggctcaccctcaccaaggatacctccaaagaccaggtggtccttgaaatgaccaacatggaccctgtggacacagccacttattactgtgctcacagacgtgtggggactgcgaccgcttttgatttctggggccaggggacaacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10604 JY8QFUQ01AMKYK No results +10605 JY8QFUQ01DTIM6 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 878 89.45 195/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) gcctcctggattcacCctttggttattatggcatgactggtccgccaagctccggggatgggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10606 JY8QFUQ01CKI20 No results +10607 JY8QFUQ01B8D22 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 890 90.7 195/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD5-18*01 F 3 10 7 17 10.7.17 [1.17.38.11] CAGEQMIDAVSHNYAMDVW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01B8D22 ; 8 AA in Homsap_IGHV4-59*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggctccatcagcatcaatacttacttctggagttggatccggcagcccccagggaagggactggagtggattgggtatatctctcacagtgggagtgccaactacaacccctccctcgagagtcgagtcaccatcttaagagacacgtccaagaaccagttctctctgaggctgagggctgtaaccgcggcggacacggccgtgtatttctgtgcgggggaacagatgattgacgcagtctcccacaactatgccatggacgtctggggccaagggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgacgcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +10608 JY8QFUQ01CEH7I productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 918 91.24 198/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKGRGYNDYGLDYW in-frame + ctctggattcaccttcagtgactatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtgacagttattttatatgatggaagtagaaaatactatgcagactccgtgaagggccgattcgccatctccagagacgtttcgaggaacacgttgtatctgcagatgaatagcctgagacctgaggacacggctgtatactactgcgcgaaaggacgtggatataatgactacggcctcgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10609 JY8QFUQ01CVO57 productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttcccc +10610 JY8QFUQ01DHV9M unknown (see comment) Homsap IGHV3-48*01 F 820 86.3 189/219 nt 85.84 188/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); gcctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaTggggctggagtgtgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctgggactctgggggcccaagggaccacggtcgccgtctccctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10611 JY8QFUQ01B45Q5 productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10612 JY8QFUQ01BP7R4 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1076 97.36 221/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgagaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10613 JY8QFUQ01ADMJX productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaggagttattattggagttggatccggcagccCcccaggaaagggactggagtggattggttatattaattatgttgggggAcaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10614 JY8QFUQ01BKW6J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10615 JY8QFUQ01BE6BR productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [1.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10616 JY8QFUQ01BU14D productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*07 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 928 91.78 201/219 nt 90.87 199/219 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [2.17.38.11] CAKDREDSSGYYFFRDGFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); gcctctggattcaTgcttcagCaagccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagatcgtgaagatagtagtggttattacttcttccgtgatggttttgatatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10617 JY8QFUQ01BMDI0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10618 JY8QFUQ01AWFVX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10619 JY8QFUQ01DDMV5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagccctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10620 JY8QFUQ01BAGLD productive Homsap IGHV1-2*02 F 822 87.38 187/214 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARQRGPGIGTVGLDYLG in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatatgtcttcaatgactactatatacactgggtgcgacaggcccctggacaaggacttgagtggatggggtggatcaaccccaccagtggtgtcacaaactatgcgcagaagtttcagggcaggatcgtcatgaccagggacacgtccatcgatacagcctacttggaggtgaccagggtgaagtttgacgacacggccgtctattactgtgcgcgacagagaggtcccggtatagggacagttggcttggactatttgggggccaggggtaccctagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +10621 JY8QFUQ01DL7V8 No results +10622 JY8QFUQ01B0YNB No results +10623 JY8QFUQ01C1YGN No results +10624 JY8QFUQ01BKECC No results +10625 JY8QFUQ01DNPGO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - agcctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10626 JY8QFUQ01B4MWK productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 780 84.09 185/220 nt 83.64 184/220 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [2.17.38.11] CARDGSAHSPISHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); agcctctggaAttctccttaagttctcatacaatgaattgggtccgccaggctccagggaaggggccggagtgggtctcaactattggcaccagagggagatccatatactacgcggactcagtgaagggccgattcatcacctcgagagacaacgccgggcacgcactatatctggagatgcacaacctgagagccgaggacacggctatgtattactgtgcgagagatggtagtgctcactcgccaatctcacattactattacggcatggacgtctggggccaagggaccacggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10627 JY8QFUQ01DQF6F productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1013 95.87 209/218 nt Homsap IGHJ1*01 F, or Homsap IGHJ4*02 F (see comment) 145 78.72 37/47 nt Homsap IGHD4-17*01 F 2 8 8 6 8.8.6 [1.17.38.11] CANYGQWL in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctaattacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10628 JY8QFUQ01BHQWH No results +10629 JY8QFUQ01CJWBE productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame - ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10630 JY8QFUQ01DPZU3 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF## out-of-frame - ctctaaagttcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcacaggtattagtggtggtggtgaaaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagagcatgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10631 JY8QFUQ01C2U95 No results +10632 JY8QFUQ01B5Z4M No results +10633 JY8QFUQ01CZU05 unknown (see comment) Homsap IGHV2-5*03 F 172 54.45 104/191 nt 10 7 X 10.7.X [9.17.25.X] null + No rearrangement found accctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +10634 JY8QFUQ01CJFIA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10635 JY8QFUQ01BAAGC unknown (see comment) Homsap IGHV3-74*03 F 117 54.07 73/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtacctactggatgcactgggtccgccaagttccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10636 JY8QFUQ01AWH4C productive (see comment) Homsap IGHV4-4*07 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD4-17*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARDLPTVTTGALDIW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); ctctggtggctccttcagtaattaccactggagctggatccggaagcccgccgggaaggaactggagtggattgggcgtatccatcacagtgGggctcaccaactccaacccctccctcaagaatcgagtcgtcgtgtcagtggatacgtccaagaatcagttgtccctggagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagatcttcctacggtgactactggggctcttgatatctggggccaagggacaatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctggactgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10637 JY8QFUQ01A2KE1 No results +10638 JY8QFUQ01A5679 productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ6*04 F (see comment) 90 60.32 38/63 nt Homsap IGHD2-21*02 F 2 8 8 20 8.8.20 [2.17.38.11] CAKDRTLHTPAQMFYYGMDAWG in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); gcctctggatttaccttcagttcttatagtgtcaactgggtccgccaggctccagggaagggcctggagtGgggtctcatatattgataatagtggttctaccatatattatgcagactctgtgaagggccgattcaccatctccagagacaatgcccagaactcactgtttctgcaaatgaacagcctgcgagccgaggacacggccgtttattactgtgcgaaagatcggacactacacacacccgctcagatgttttattatggtatggacgcctgggggcccaaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10639 JY8QFUQ01B7EF5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 809 86.51 186/215 nt 85.58 184/215 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 7 12 8.7.12 [1.16.38.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaagggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtgcgtggaactc +10640 JY8QFUQ01CQBXU productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 871 90.14 192/213 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10641 JY8QFUQ01CUS6E productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10642 JY8QFUQ01BT3LW No results +10643 JY8QFUQ01CYBZL productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [1.17.38.11] CACYFDSNGFFDYW in-frame + ttctggatacgtctttccctcctactggatcgcctgggtgcgccagatgcccggtaaaggcctggagtggctgggaaccatctatcccggcgactctgacaccacatacagcccgtcattccaaggccaggtcaccatgtcagtcgacacgtccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacagcgccatttactattgtgcgtgttattttgatagtaatggtttctttgactactggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10644 JY8QFUQ01CLMUE unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F (see comment) 557 73.02 157/215 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt Homsap IGHD5-18*01 F 3 8 8 X 8.8.X [0.17.38.6] PV## out-of-frame - Low V-REGION identity (73,02% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10645 JY8QFUQ01CC7RP productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATSRGSANWYPFDHW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 66 of V-REGION: 'G' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacaGttttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10646 JY8QFUQ01AEXAB unproductive (see comment) Homsap IGHV3-11*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSX*F*VL in-frame + stop codons cctctggcttcaccttcagtgactactacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtggaagtggaactaccatatcctacggagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtatctccagatgaacagcctgagagccgaggacacggccgtatattactgtgtgaggcgggtgtggggatacagctatggttccgtctcgnactgattttgagtactgggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggccttcttccc +10647 JY8QFUQ01A1J69 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGHW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10648 JY8QFUQ01CXE58 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 822 87.38 187/214 nt 86.92 186/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.38.11] CARGRTVVTVIDYIDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); ctctggggactccattagtggttactattggacgtggatccggcagAcccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10649 JY8QFUQ01ALF1M unproductive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 10 7 X 10.7.X [1.17.38.11] CATIVPSSVTALINDQGRFYFDH## out-of-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtcgtcgtggaactcag +10650 JY8QFUQ01BCH6P productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10651 JY8QFUQ01CUGGP productive (see comment) Homsap IGHV3-33*05 F (see comment) 752 83.03 181/218 nt 82.57 180/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.16.38.11] CVKGRGYNDYGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaagggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10652 JY8QFUQ01C8Z01 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10653 JY8QFUQ01B6DL7 productive Homsap IGHV3-66*02 F 894 91.12 195/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaagaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10654 JY8QFUQ01CZO4B productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 880 88.74 197/222 nt 87.39 194/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 1 8 10 9 8.10.9 [1.16.38.11] CTTWFDDFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'A' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) ctctggactcactttcagcaacgcctggatgagatGgggcccgccaggctccagggagggggctgagtgggttggccgcattaaaagtaaagctgatggtgggacaacagacAtttgatgcagccgtgaaaggcagattcaccctctcaagagacgattcgaaaaatacgatatatctgcaaatgaatcgcctgaagactgaggacacaggtgtttattactgtaccacatggttcgacgactttgactactggggcccgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10655 JY8QFUQ01B1DNN unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F or Homsap IGHV7-81*01 ORF 139 58.88 63/107 nt 8 8 X 8.8.X [0.17.2.X] null + No rearrangement found cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10656 JY8QFUQ01DK6WS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-10*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGAAVALTPG in-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtgcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10657 JY8QFUQ01C4YGB productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 912 90.13 201/223 nt 89.69 200/223 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 2 8 10 15 8.10.15 [1.17.37.11] CTTDRRGLSIPPQFDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 162 in the user submitted sequence), (cause frameshift) cctctggattcactttcagtgacgcctggatgagctgggtccgccagattccagggaaggggctggagtgggttggccgtataaaaaacaaagctatgggtgagacaacagacttcgctgcacccgtgagaggcagattcagtatctcaagagatgattcaaaaatacactgtatctgcacatgagtggcctgaaaaccgaggacacagccgtctattattgtaccacagatcggcggggtttgtctataccacctcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10658 JY8QFUQ01CIOEY No results +10659 JY8QFUQ01AZEAD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10660 JY8QFUQ01A92S8 productive (see comment) Homsap IGHV3-30*10 F (see comment) 761 83.49 182/218 nt 82.57 180/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); cctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcaCgcagtctcacatgatggtgttagcgagatgtatacagaCccccgtgaagggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +10661 JY8QFUQ01C4QZS productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGHW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10662 JY8QFUQ01C8FDH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CAKAVPTRVRLDHW in-frame - ctctggattcgactttaacaactttgccatgacctgggtccgccaggctccagggaagggtctggagtgggtctcaggtatcagtggtggcggttttaatacatactacgcagactccgtgaagggccggttcaccgtttctcgagacaagtccaacaacacgttgtttctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaaagccgttcccaccagagtcaggcttgaccattggggccacggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10663 JY8QFUQ01B8FQE No results +10664 JY8QFUQ01BDMOG productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.16.38.11] CTKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagatactggGatgcactgggtccgccaggctccagggaaggggctggagtggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10665 JY8QFUQ01A3PVQ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 838 87.21 191/219 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKSPLSVAGTRQNWFD#PG out-of-frame - gctctgacttgcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctgggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10666 JY8QFUQ01CNN4B productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10667 JY8QFUQ01ADMPT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + cctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10668 JY8QFUQ01CMBYX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame + ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc +10669 JY8QFUQ01AGHV3 productive (see comment) Homsap IGHV4-61*02 F 874 89.04 195/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 114 in the user submitted sequence), (cause frameshift) ctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10670 JY8QFUQ01CNKLI No results +10671 JY8QFUQ01BXLNA productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagccctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactca +10672 JY8QFUQ01CNHY7 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*15 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F (see comment) 694 79.91 175/219 nt 79.45 174/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-1*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRSPNHNWFDPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 93 of V-REGION: 'A' (1 nucleotides at position 184 to 184 in the user submitted sequence), (cause frameshift); ggctctggattcaaattcaataattatgcaatgcactgggtccgccagtctccaagagcggggctgcaatgggtggcggctatatcgactgacggcaataaagaatatcatgcagactccgtgaagggccggctcaccctctccagagacaattcgaggagtacgctgtctctgcaattgcgcAaacctgacagctgacgactcggctctgtattattgtgtcagatctcccaaccacaattggttcgacccctggggccagggagccctggtcactgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10673 JY8QFUQ01C1R7S productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 7 8 11 7.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) cctctggatttactttaacaactattggatgacctgggttcgccaggctccagggaaggggctggagtgggtctcagGgtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10674 JY8QFUQ01A7IGG productive (see comment) Homsap IGHV3-7*01 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); gcctctacattcacgGtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10675 JY8QFUQ01BYVL8 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 493 92.92 105/113 nt 92.04 104/113 nt 8 8 X 8.8.X [1.16.4.X] null + No rearrangement found in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaagggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagac +10676 JY8QFUQ01DNC02 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca +10677 JY8QFUQ01AR8UJ productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 94.17 210/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.37.11] CTTGGGTNYYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 162 in the user submitted sequence), (cause frameshift) cctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10678 JY8QFUQ01BLALJ productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 869 86.78 197/227 nt 85.9 195/227 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*02 F 2 8 10 12 8.10.12 [2.17.38.11] CSYFRHEPYHFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); tagacgctggattcgcctctggtgattatgctatgagGttggttccgccaggctccgggcaaAGggggctggagtgggtggggttcatcagaagcagagcttacactgggacaccagaatacgccgcgtctgtgaaaggcagattcaccatctccagagatgcttccaaaagtattggctatctgcaaatgaacaatctgaggatcgaggacacagccgtctattattgctcttattttcggcatgagccatatcactttgactattggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10679 JY8QFUQ01B9V5M productive Homsap IGHV3-48*01 F 810 86.18 187/217 nt Homsap IGHJ6*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 1 8 8 8 8.8.8 [1.17.38.11] CVRGAGLDVW in-frame + ctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaggggctggagtgtgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctggacgtctggggccaagggaccacggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +10680 JY8QFUQ01DDV5C unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F (see comment) 768 82.96 185/223 nt 81.61 182/223 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 1 8 10 X 8.10.X [1.17.38.11] CSTGGPNGYHSTYPW# out-of-frame + Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); ctctggattcgccttcaatatcaagtggatgagttgggtccgccaggctccGggggaaggggcttgagGtgggtcggccgcatcaagagcagcgctgatggtgcgacaacagacaccattgagcgcgtgagagacagattcaccatctcaagagatgactcaaaaaaGtacactgtacttgcacatgaccagcctgagaaccgaggacacaggcatgtattattgttccacaggcgggccaaatggatatcactccacatatccctgggggcccgggggacccaggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10681 JY8QFUQ01AA9FJ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10682 JY8QFUQ01BMJLY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [2.17.38.11] CAKEGNLGYFDDW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) gcctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10683 JY8QFUQ01AYJ8O No results +10684 JY8QFUQ01AF6U3 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 824 86.7 189/218 nt 86.24 188/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.17.37.11] CVRDSDSSGYARYDSMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 100 of V-REGION: 2 nucleotides (from position 207 in the user submitted sequence), (cause frameshift) agcctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10685 JY8QFUQ01C4E75 productive Homsap IGHV4-61*07 F (see comment) 766 83.56 183/219 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Low V-REGION identity (83,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) gtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcacccctcctcccaagagcacctctgggggcacagcggcccctgggctgcctggtccaagggactacttcccccgaaccggtgacggtgtcgtggaact +10686 JY8QFUQ01BWFM1 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) cctccgggattcaccttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10687 JY8QFUQ01A78NA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ2*01 F 242 94.34 50/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFXLW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcnatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10688 JY8QFUQ01CTCXB productive Homsap IGHV1-18*01 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [0.17.38.11] CATSDVGARKFDYW in-frame - tggttacacctttaccagatatggtattagttgggtgcgacaggcccctggacaagggcttgagtggataggatggatcagcgtttccaatggtgacacaaactatgcacagaagctccagggcagagtcaccatgaccgcagacccatccacgagcacagcctacttggaactgaggagcctgacatctgacgacacggccgtatattactgtgcgacatctgacgttggagctcgaaagtttgactactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10689 JY8QFUQ01B9BPY productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1080 97.79 221/226 nt 97.35 220/226 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtCccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10690 JY8QFUQ01DDCCT productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 967 92.44 208/225 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [5.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ccgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10691 JY8QFUQ01CE3EU No results +10692 JY8QFUQ01BB4PW productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10693 JY8QFUQ01BW6L0 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.37.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 194 in the user submitted sequence), (cause frameshift) ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggcccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcacccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10694 JY8QFUQ01DRJLJ No results +10695 JY8QFUQ01AKYM1 No results +10696 JY8QFUQ01BOPT4 productive (see comment) Homsap IGHV3-66*02 F 899 91.16 196/215 nt 90.23 194/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.16.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) agcctctggattcaccgtcagtagcagcttcatgacttgggtccgccagctccaggaaaggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcgactgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10697 JY8QFUQ01DUYT0 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttacccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10698 JY8QFUQ01AB8R5 productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10699 JY8QFUQ01ASFP7 No results +10700 JY8QFUQ01BAD27 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10701 JY8QFUQ01A4PFT No results +10702 JY8QFUQ01B2TU9 No results +10703 JY8QFUQ01CB3JH productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 2 9 7 14 9.7.14 [1.17.38.11] CARPARPSAVGPFDFW in-frame - tctctggtgactccatcagcggtagcaattggtggagttggatccgccagcccccagggaaggggctggagtggattggggaaatctctcatagtgggaacactaactacaacccgtccctcaagagtcgggtcaccatatcagtcgacaagtccaagagccagttctccctgaacctgagcgctgtcaccgccgcggacacggccgtatattactgtgcgagacctgctcgcccatcggccgtgggaccctttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10704 JY8QFUQ01AZPLL unknown (see comment) Homsap IGHV4-4*08 F, or Homsap IGHV4-61*05 F 173 56.69 89/157 nt 8 7 X 8.7.X [1.17.18.X] null + No rearrangement found stop codons tctctggtggctcgctcacgggtttcaagtggggctggatccggcagcccccaggggagggactgcaatggattggacatatctcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +10705 JY8QFUQ01CKTX3 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 936 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggcgtgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10706 JY8QFUQ01CKS0C productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 855 88.48 192/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CTRVGTFNWFGPW in-frame + ctctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +10707 JY8QFUQ01BRNG5 productive (see comment) Homsap IGHV3-13*01 F 970 95.31 203/213 nt 94.37 201/213 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 7 7 13 7.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 97 of V-REGION: 'T' (1 nucleotides at position 190 to 190 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) ctctggattcacgttcagtaatacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccTggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10708 JY8QFUQ01ACENJ productive Homsap IGHV3-21*04 F 985 95.37 206/216 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame + tctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10709 JY8QFUQ01DBQ14 No results +10710 JY8QFUQ01ACK8R productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10711 JY8QFUQ01DV8NC productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-13*01 F 3 8 7 12 8.7.12 [2.17.38.11] CARGVGQQLPPLDW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); gtctctcgtgcctccatGcaatatttcctactggagctggatccggcagcccccagggaggggactggagtggattggatatatctatgatagtgggagtaccaactacaacccctccctcaagagtcgagtcaccatatctatagacacgtccaagaaccagttctccctgaggctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgaggggggtggggcagcaactgccccccttagactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10712 JY8QFUQ01DKWN3 No results +10713 JY8QFUQ01BDPXU productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 888 89.55 197/220 nt 88.64 195/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); ctctaatggctccatcagcggaagtgtttactactgggcctgGgatccgccagcccccagagaagggtctggagtacattgggaAgcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttctccc +10714 JY8QFUQ01BANH8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 8 21 8.8.21 [1.17.38.11] CARVMREHYYGAGNYPWGGMEVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcacctttaacaactatgccatgacctgggtccgccaggctccggggaaggggctggagtgggtctcagctatcagtggcagtggcggtaccacttactacgcagactccgtgcagggccgcttcaccatttccagagacaatcacgaaaacaccctgtatctggaaatgagtagcctgagagccgaggacgcggccgtctattactgtgcgagagtgatgagggaacattattatggagcggggaattatccctgggggggaatggaagtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10715 JY8QFUQ01B2H4W productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 775 84.02 184/219 nt 83.56 183/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); tgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGgggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +10716 JY8QFUQ01ALGEH unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CANELGYCSGG# out-of-frame - ctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10717 JY8QFUQ01DE2T0 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 786 85.51 183/214 nt 85.05 182/214 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-23*01 ORF 2 8 7 17 8.7.17 [1.17.38.11] CAGEEMRTRDGGGYGTDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); ctctggtgGgctccatgactctttattattggagttggatccggcagcccgcagggaaggggctggagtgggttgggtacatcgatcacgctgggagcgccaagtataacgcctcccttcagagtcgagtcaccatctcagtcgacgcgcccaagaatcagttctctctgaagttgaactctgtgactgctgcggacacggccgtttattactgtgcgggagaagagatgcgaacgcgggacgggggtggctacggaacggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10718 JY8QFUQ01BR9IG productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 890 90.7 195/215 nt 89.3 192/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [2.16.38.11] CTRELRVAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 81 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcagtaccaagGttcatgagctgggtccgccaggctccagggaagGgggctggagtgggtctcagtaattatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10719 JY8QFUQ01AM9UU No results +10720 JY8QFUQ01CEUTU unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 454 72.63 130/179 nt 8 8 X 8.8.X [1.17.25.X] null - No rearrangement found Low V-REGION identity (72,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10721 JY8QFUQ01AMSO8 unknown (see comment) Homsap IGHV3-21*04 F (see comment) 667 78.54 172/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (78,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctccggtttcatcttcagtcacttcagcatgaactgggtccgccaggctccaggaaagggcctggagtggatcgccgacatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcgacgatacggccacctattattgtgtgaggctcttcaccagcgatggagtgagaggcgactactgggggccagggcgcccgggttctcgtctccgcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10722 JY8QFUQ01BNGHM productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 82 to 87 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgTcctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +10723 JY8QFUQ01AIWOI productive (see comment) Homsap IGHV3-48*03 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagttcttatgccatgaactgggtccgcctggtccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +10724 JY8QFUQ01DRCAF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 927 91.74 200/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'GG' (2 nucleotides at position 56 to 57 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) gcctccggattcacctttagtagtactggatgcactgggtccgccaagctccaggGGgagggactgggtntgggtctcacggaCtaaatgaagatgggagtatcacGaaactacgAcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10725 JY8QFUQ01BZF9G unproductive Homsap IGHV3-48*02 F 976 94.91 205/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGEGDPFF##YYSGLDVW out-of-frame - tctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10726 JY8QFUQ01CRF3X No results +10727 JY8QFUQ01BOALS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10728 JY8QFUQ01CFMY9 productive (see comment) Homsap IGHV4-4*07 F 786 85.51 183/214 nt 84.58 181/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 6 15 8.6.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'AGGC' (4 nucleotides at position 76 to 79 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 92 in the user submitted sequence), (cause frameshift) tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgAGGCgtcatctctgttcttgaaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10729 JY8QFUQ01BBYJ2 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10730 JY8QFUQ01AYJEJ productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10731 JY8QFUQ01BEYE8 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 103 52.99 71/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacctttagtgactattggatgagctgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10732 JY8QFUQ01CIT4F productive Homsap IGHV3-48*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARESTWEFTPDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcagtttcagtgactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagttctagtagtaccctatattatgcagactctgtgaagggccgattcaccgtctccagagacaatgacaagagttctctgtatctgcaaatgaccggcctgagagccgaagacacggcgacttattactgtgcgagagagtcgacgtgggaatttactcctgactcctggggcccggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +10733 JY8QFUQ01CVI49 productive Homsap IGHV3-48*02 F 976 94.91 205/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARPAGEGDPFFHYYSGLDVW in-frame + tctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10734 JY8QFUQ01B9RQR No results +10735 JY8QFUQ01DAZD6 No results +10736 JY8QFUQ01BVRVR productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 963 92.04 208/226 nt 91.59 207/226 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt 8 7 9 8.7.9 [5.17.38.11] CARGGPHFYDS (see Functionality comment) in-frame - Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); gccgtctgcagcctctggattcCattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggcccccacttttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10737 JY8QFUQ01A5SB0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtcttctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10738 JY8QFUQ01BRQ8F productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10739 JY8QFUQ01A95F9 productive Homsap IGHV3-74*03 F 846 88.02 191/217 nt Homsap IGHJ1*01 F 134 73.08 38/52 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggcagccctggtcacgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttccccca +10740 JY8QFUQ01AL3XX productive Homsap IGHV3-9*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattacttggaacagtggtaggataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +10741 JY8QFUQ01B9L1U productive (see comment) Homsap IGHV2-5*02 F 1134 96.31 235/244 nt 95.49 233/244 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-17*01 F 3 10 7 13 10.7.13 [9.17.38.11] CAHFSVTTPYGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 81 of V-REGION: 'G' (1 nucleotides at position 173 to 173 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 185 to 185 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttctctgggttctcactcaccactactggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcagtcattttttgggatgatgatgagcgccacagcccatctctgaggagaaggctcaccatcaccaagGgacatctccaaAaaaccaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacttttcggtgactaccccatatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggctcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10742 JY8QFUQ01BZY5S productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 967 92.44 208/225 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 7 14 8.7.14 [5.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10743 JY8QFUQ01AJO4L unproductive (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F (see comment) 342 61.75 134/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found Low V-REGION identity (61,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattacttggaacagtggtaggataggctatgcggactcttgtattattgtgcaaaagatatggggtatacctggaagtacattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10744 JY8QFUQ01BD0HS No results +10745 JY8QFUQ01CFOEY No results +10746 JY8QFUQ01AN3J7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.99 194/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame - cctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10747 JY8QFUQ01AFIHV No results +10748 JY8QFUQ01C8MU7 No results +10749 JY8QFUQ01ASHDH No results +10750 JY8QFUQ01CUDH9 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANYW# out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10751 JY8QFUQ01B6YTM productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 921 92.52 198/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - ctctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatcccctaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10752 JY8QFUQ01A35PD No results +10753 JY8QFUQ01COVYR No results +10754 JY8QFUQ01DJ040 unproductive (see comment) Homsap IGHV3-72*01 F 853 87.39 194/222 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 1 8 10 X 8.10.X [1.17.38.11] CAVAAPPL#DGW out-of-frame + stop codons tctggattcaccttaagtgacttctacatggactggctccgccaggctccagggaaggggcctggatgggttggtcgcagtagaaacaaagctaatggttacagtacacaattcgccgcatctgtgatgggcagattcaccatctcaagagatgactcaaagaatttactatatctacaaatgagcagcctgaaaaccgaggacacggccatttattactgtgctgtcgcagcccccccgttatgacggctggggccagggaaccctggtcatcgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagccaccccccctcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10755 JY8QFUQ01BBP33 No results +10756 JY8QFUQ01BIJZ5 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame - tctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10757 JY8QFUQ01CR3NS No results +10758 JY8QFUQ01ASM1Z productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt 88.69 196/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcCccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10759 JY8QFUQ01B6OVD No results +10760 JY8QFUQ01CKO1P productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 809 84.82 190/224 nt 83.93 188/224 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD3-16*01 F 2 8 10 13 8.10.13 [2.16.38.11] CSTGGPNGYESTYPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) gcctctggattGcaccttcaatatcaagtggatgagttgggtccgccaggctccgggaaggggctggagtgggttggccgcatcaagagcacctctgatggtgggacaacagactccattgcacacgtcaaagacagattcatcatctcaagagatgattcaagaaatacactgtacttacaaatgaacaacctgagagtcgaggatacaggcgtctattattgttccacaggagggccaaatggttatgagtctacctatccctggggcccgggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10761 JY8QFUQ01AH452 productive Homsap IGHV3-11*01 F 944 93.49 201/215 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD1-26*01 F 3 8 8 16 8.8.16 [0.17.38.11] CARDGDDYRSYYYGMDVW in-frame - ctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcatggtatacctggcagactctgtgaagggccgattcatcatctccagggacaacggcgagaactcactgtatcttcaaatgaacagcctgagagccgaagacacggccgtgtattactgtgcgagagatggggacgactacaggtcgtactactatggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10762 JY8QFUQ01BIAPA No results +10763 JY8QFUQ01B7GKQ productive (see comment) Homsap IGHV4-61*02 F (see comment) 754 82.43 183/222 nt 81.98 182/222 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 10 7 16 10.7.16 [2.17.38.11] CARERFRSTGGARDFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,43% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); gtctctggtgAgccccatcagcagtggtgatcacttctggagctggatccggcagcccgccgggaagggactggagtggattggacatgttcactatggtggggtcaccaattacaatccttccctccagggtcgggtcatggtgtctatggacacgtccaagagccagttcttcctgacgatgacctccgtgaccgccgcagacacggccacatattactgtgcgagagagcgtttcaggtcgacgggcggagcgagagattttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10764 JY8QFUQ01CD8YB productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10765 JY8QFUQ01AO9ZD productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10766 JY8QFUQ01BZSD2 productive (see comment) Homsap IGHV3-11*01 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggcagtgctactaccatatcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaaaaaGctcactttatctgcaaatggacagcctgagagccgaggacacggccatatattactgtgtgaggcgggtgtggggatacagttatggttccgtttcgtactactttgaatactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10767 JY8QFUQ01BDE5D productive Homsap IGHV4-61*02 F 875 88.69 196/221 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD4-11*01 ORF 3 10 7 9 10.7.9 [1.17.38.11] CTKLLNHFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctccatcaatggaggcagttcctactggagctgggtccggcagcccgccgggaggggactggagtggattgggcgtatctatctcagtgggagcaccaactacaatccctccctcaatgatcgagccaccatctcaatcgacccgtccaagaaccagttctccctgaaactgaggtttgtgaccgccgcagacacggccgtatactattgtactaaactacttaaccacttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaacctcag +10768 JY8QFUQ01CO019 productive Homsap IGHV3-11*01 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 14 8.8.14 [1.17.38.11] CTRDDRSVRGVTSDYW in-frame + tctggattcaccttcagtgaccacttcatgagttggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggcagtggtagtataatatattacgcagactctgtgaggggccgattcaccatctccagggacaacgccaagaattccctctatctgcaaatggacagcctgagagacgaggacacggccgtgtatttttgtacgagagatgatcgctcggttcggggagtcacctcagactactggggccagggaaccctggtcaccgtctcctccgcctcctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcagg +10769 JY8QFUQ01DAK9T unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 953 93.95 202/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 7 X 8.7.X [1.17.38.11] CASSV*GGQLWPGEL# out-of-frame + stop codons tctctggtggctccatcagtaattacttctggagctggatccggcagcccccagggaagggtctggagtggattgcgaatatctattacaatgggaacaccaactacaacccctccctcaagagtcgagtcaccatatctatagacacgtctaagaaccagttctccctgaaggtgaggtctgtgaccgctgcggacacggccgtgtattattgtgcgagctcagtttaggggggccagctatggcctggggaactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggggcttcttcccccga +10770 JY8QFUQ01C6I13 productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +10771 JY8QFUQ01BR33H productive (see comment) Homsap IGHV3-11*01 F (see comment) 747 82.95 180/217 nt 82.49 179/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARVRCSGNTCGAFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 77 of V-REGION: 'N' (1 nucleotides at position 135 to 135 in the user submitted sequence), (cause frameshift); ctctggattcagcttaagtgactactacatgacctgggtccgccaggccccagggaagggactggagtggctcgcctacattagtcgaactgatgattccgtatattccgcagagtctgtggtgggccgattcaNccgtctccagggacaacgtccaaaactcacttgttttgcagatgattggcctgagagacgaggacacggccgtatattactgtgcgagagtccgctgtagtggtaatacctgcggggcttttgatttgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10772 JY8QFUQ01B161I unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARVRGYYGGQYFDS## out-of-frame + ctctggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +10773 JY8QFUQ01A0VAL No results +10774 JY8QFUQ01BR81F unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRGGVSGAFRWG#FDYW out-of-frame + stop codons ctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgacgacacggctgtttactactgtgtgagagggggagtcagtggggccttcaggtgggggttttgactactggggccagggaaccctggccaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10775 JY8QFUQ01CKC0K unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F (see comment) 541 71.69 157/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (71,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ggttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10776 JY8QFUQ01B8DCT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + tctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10777 JY8QFUQ01BN3GL No results +10778 JY8QFUQ01BNQSK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKNMAMGEALFDFW in-frame + gtctggattcacctttagtgattatgccttgagctgggtccgccagactcccgggaaggggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgaaaaacatggctatgggagaggcgttgtttgacttctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10779 JY8QFUQ01B8I5W productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10780 JY8QFUQ01A9569 productive Homsap IGHV3-43*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDRIGSLNYFDHW in-frame + cctcagggttcaactttgatgaatataccatgcactgggtccgtcaagctccggggaagggtctggagtgggtctctcttattagttgggatggtagcagcacatactatgcagactctgtgaagggccgattcaccatctccagagacaacagcaaagattccctgtatctgcaaatgagcagtctgagagctgaggacgccgccttctattattgtgcaaaggataggattgggtccttgaattactttgaccattggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +10781 JY8QFUQ01B1TMD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 940 93.06 201/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + tccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10782 JY8QFUQ01BVM4A No results +10783 JY8QFUQ01BSUM5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +10784 JY8QFUQ01A7I0L productive Homsap IGHV3-48*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDQSPGVAVAGPDYW in-frame + ctctggattcaccttcagtagatatagtatgaactgggtccgccaggctccaggaaagaggctggagtgggttgcatacattagaagtagcagtagtgtcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcaaagtccgggtgtagcagtggctggtcctgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagccaccccccaanatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +10785 JY8QFUQ01B1O5A productive Homsap IGHV3-7*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10786 JY8QFUQ01AXTVE unproductive (see comment) Homsap IGHV4-61*02 F 893 89.59 198/221 nt 89.14 197/221 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 10 7 X 10.7.X [1.17.38.11] CARQGG**WTLE*LL# out-of-frame + stop codons in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 216 to 216 in the user submitted sequence), (cause frameshift); tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatTttttgtgcgagacaagggggatagtagtggaccctggaatgactactgggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10787 JY8QFUQ01DIGTH unproductive Homsap IGHV3-9*01 F 971 94.88 204/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [0.17.38.11] CAKILGYTCGP#DYW out-of-frame + ctggattcacgtttgatgactatggcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggcattacttggaatagtggttacataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctacagatgaacagtctcagagctgacgacacggccttgtattactgtgcaaagatattggggtacacatgtggaccattgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10788 JY8QFUQ01AUOZJ productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 903 91.59 196/214 nt Homsap IGHJ3*02 F (see comment) 133 74.0 37/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaacggtcaccggtctcttcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +10789 JY8QFUQ01AZTV5 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-16*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARHNYGNEKYIMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'GA' (2 nucleotides at position 27 to 28 in the user submitted sequence), (cause frameshift); ttggatacaactttgccacctattggGAtcgggctgggtgcgccacatgcccgggaaaggcctggaatggatggggatggtctttgctggtgactctgacaccagatacagtccgtccttccgaggccaggtcaccatgtcagccgacaagtccatcaacaccgcctacctgcagtggagcagcctgatggcctcggacaccgccatatattactgtgcgagacataattatggaaacgagaagtacattatggacgtctggggccaggggaccacggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10790 JY8QFUQ01BOSCN productive (see comment) Homsap IGHV4-4*07 F (see comment) 679 79.63 172/216 nt 79.17 171/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-9*01 F 2 8 7 16 8.7.16 [2.17.38.11] CARESTNSIGDPRHLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'CAANACGAC' (9 nucleotides at position 19 to 27 in the user submitted sequence), (do not cause frameshift); gtctctggtggccccatcCAANACGACatggacttctattggacgtggatccggcagtccgccgggaggggactggagtggctcggacatgtctatatgaatggcattagtgaccacaatccagtcttcactagtcgtctcaccatgtccattgacacgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcggactcggccctatattactgtgcgagagaaagtactaattcgattggcgacccgagacaccttgactcttggggccagggaaggttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10791 JY8QFUQ01B53GB productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 897 90.0 198/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10792 JY8QFUQ01BZPA4 productive Homsap IGHV3-11*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame + ctctggcttcaccttcagtgactactacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtggaagtggaactaccatatcctacggagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtatctccagatgaacagcctgagagccgaggacacggccgtatattactgtgtgaggcgggtgtggggatacagctatggttccgtctcgtactattttgagtactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10793 JY8QFUQ01AT7VB productive Homsap IGHV3-15*07 F 993 94.17 210/223 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-10*01 F 3 8 10 22 8.10.22 [1.17.38.11] CTTAGITMVRGIIINGDYYGMDVW in-frame + ctctggattcactttcagtaacgcctggatgaactgggtccgccaggctccaggtaaggggctggagtgggtcggccgtattaaaagcaaaggtgatggtgggacaacggactacgctgcacccgtgaaaggcagattcagtatctcaagagatgattcagaaaacaagttgtatctgcaaatgaacagcctgaaaaccgaggacacaggcatatattactgtaccacagccggtattactatggttcggggaattattataaacggtgactattatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagtgggaacgtggtcatcgcctgcctggtccagggcttcttcccccagg +10794 JY8QFUQ01BN655 No results +10795 JY8QFUQ01A86H8 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 85 57.75 41/71 nt 8 X X 8.X.X [1.14.X.X] null - No rearrangement found ctctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttcccca +10796 JY8QFUQ01DLPCH productive (see comment) Homsap IGHV1-2*02 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARGGATWELLLGNLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 69 of V-REGION: 'GC' (2 nucleotides at position 110 to 111 in the user submitted sequence), (cause frameshift); tggatacacgttcaccgactactatgtccactgggtgcgacaggcccctggacaagggcttgagtggatggcgtggatcaaccctaacattggtgtcaccaagtctgcaGCcaaaaatttcagggcagggtcaccatgaccagggacacgtccatcagcacagccttcatggagctgagcagcctgagatctgacgacacggccgtttattactgtgcgagagggggggcgacgtgggaactattattggggaatcttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10797 JY8QFUQ01DTEZT unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 913 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CAGGQRLGL#DYW out-of-frame + in FR3-IMGT at codon 99 of V-REGION: 'G' (1 nucleotides at position 201 to 201 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'T' (1 nucleotides at position 212 to 212 in the user submitted sequence), (cause frameshift); ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacaGcggctntataTtttctgtgcggggggccagaggctgggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10798 JY8QFUQ01AA9UM productive Homsap IGHV4-61*02 F 1010 95.48 211/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*02 F 2 10 7 15 10.7.15 [1.17.38.11] CARAGKQDFWSGYSDDW in-frame + tctctggtggctccatcggcagtggtagttattactggagctggatccggcagcccgccgggaagggactggaataccttgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgctgacacggccatttattactgtgcgagagcggggaaacaggatttttggagtggttattctgacgactggggccagggaaccctggtcatagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10799 JY8QFUQ01B4JYA productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccagccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10800 JY8QFUQ01BI2PW productive (see comment) Homsap IGHV3-7*01 F 997 94.59 210/222 nt 93.69 208/222 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [3.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); gcgacctctggattcaccttTtagtaaccattggatgaactGgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10801 JY8QFUQ01CFLMK productive Homsap IGHV3-11*01 F 860 88.53 193/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVDIRLGDWFFDLW in-frame + cctctggattcaccttcagtgaccactacatgagctgggtccgccaggctccggggaagggtctggaatggatctcatatatcagtacaagtggtaatatggtttattacgcggactctgtgaagggccgattcaccgtctccagggacaacaccaagagctcactgtatctgcaaatgaacggcctcagagtcgaggacacggccgtctattactgtgtcgacataagactgggagattggttcttcgatctctggggccgtggcaccctggtaactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10802 JY8QFUQ01CGL8I No results +10803 JY8QFUQ01C0VWG unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 454 72.63 130/179 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (72,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10804 JY8QFUQ01BXB22 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 866 90.09 191/212 nt 89.62 190/212 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.16.38.11] CAREFRAPSLARYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) tcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccaggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10805 JY8QFUQ01DPHF7 productive (see comment) Homsap IGHV4-61*02 F (see comment) 628 76.13 169/222 nt 75.68 168/222 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 10 7 16 10.7.16 [2.17.38.11] CARERDKSGGGAGDFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (76,13% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 34 of V-REGION: 'CGAAGGATTT' (10 nucleotides at position 24 to 33 in the user submitted sequence), (cause frameshift); gtctccagtggcattattaatagCGAAGGATTTtggtcgtttctactggaactgggtccggcagatcgacgggcaggggctggagtggatcgggcgtgtttatcgtgatgggatcacaaactacaatccctccttcgggacccgaataagtttgtcgttagactcgtccaagaggcagttttccctgaagttacagtctgtgaccgccgcagacacggccgtatatttttgtgcgagggagcgtgacaagtcgggcggcggggcgggcgactttgactcctggggccagggactcctggtcaccgtctcatctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10806 JY8QFUQ01BVRED productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 905 90.83 198/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame - ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10807 JY8QFUQ01B5QTF No results +10808 JY8QFUQ01AKBT4 No results +10809 JY8QFUQ01DRPI3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 774 84.33 183/217 nt 82.95 180/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 7 7 9 7.7.9 [2.16.38.11] CTGLTYPDDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 31 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 83 in the user submitted sequence), (cause frameshift) acgtctgggatttaccttcagtaagttctgatgcattgggtccgccaagctccagggaagggctgacttgggtctcacgtataatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10810 JY8QFUQ01DWFTQ unproductive Homsap IGHV1-69*06 F, or Homsap IGHV1-69*10 F or Homsap IGHV1-69*14 F 912 92.06 197/214 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [0.17.38.11] CAREQFYYNSGTYHHYHMDV## out-of-frame + tggagacacattcaccagctatgctatcagctgggtgcgacaggcccctggacaagggcttcagtggatgggagggatcatccccagatatggtatatcacactacgcacagaagttccagggcagagtcacgattaccgcggacagatccacgggcacagcctacatggagctgaccagcctgacgtctgaggacacggccctgtattactgtgcgagagaacaattttactataatagtgggacttatcaccattaccatatggacgtctggggccaaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10811 JY8QFUQ01CYHYD No results +10812 JY8QFUQ01B6Z1N productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 939 93.46 200/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.37.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'AG' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 100 of V-REGION: 1 nucleotides (from position 201 in the user submitted sequence), (cause frameshift) ctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtAGgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacgctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10813 JY8QFUQ01CRPFQ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10814 JY8QFUQ01CIB0W unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1125 100.0 226/226 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD1-26*01 F 3 10 9 X 10.9.X [1.17.38.11] CAREEWELPLDAFDI## out-of-frame + Other possibilities: Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) ctccggggacagtgtctctagcaacagtgctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtatctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtgtattactgtgcaagagaagagtgggagctaccgcttgatgcttttgatatctggggccaagggtacaatggtcaccgtctcttcagggagtgcatccgccccaatccc +10815 JY8QFUQ01A4VXL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctctggattctccgtcagtaattactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10816 JY8QFUQ01A0VCZ No results +10817 JY8QFUQ01DS915 unknown (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-59*08 F (see comment) 634 76.85 166/216 nt 76.39 165/216 nt 8 7 X 8.7.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (76,85% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); gtctctggtaactccatcacagattattactggagctggctccggcagtctccagggaagggactggagtggattggaaatgtcCttttacagtgggagagccaactacaacccctccctcaagagtcgagtcaccatatcagtagccacgtccaggaaccagttctccctgaagctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +10818 JY8QFUQ01BZU4R productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ5*02 F 109 70.21 33/47 nt Homsap IGHD5-12*01 F 3 8 8 6 8.8.6 [1.17.38.11] CVSIGHGV in-frame + ctctggattcgcctttaggagtgagtggatgaactgggtccgccaagccccagggaaggggctggagtgggtcgcacacattgacactgatgggagtatcgcagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaatactttgtatctgcaaatggacagtctgagagccgacgacacggctatatattactgtgtaagcattggacacggagtgggcccgggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacatggtcgtcgcatgcctggtccagggcttcttccccca +10819 JY8QFUQ01DK0WV No results +10820 JY8QFUQ01AX80T productive (see comment) Homsap IGHV3-48*02 F (see comment) 716 80.73 176/218 nt 80.28 175/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift); cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggGAaggggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggatggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc +10821 JY8QFUQ01C9SOA unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 651 83.42 156/187 nt Homsap IGHJ1*01 F (see comment) 138 74.51 38/51 nt Homsap IGHD4-11*01 ORF 2 X 8 X X.8.X [X.16.38.11] TPEIPG## out-of-frame - stop codons Low V-REGION identity (83,42% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gagtggggtccgccaggctccagggaaggggctggagtgggtctcagggctttgtggaagtgctcctaccacacactacgcagactccgtgaagggccggttcagcatctccagagacctctccaagaatgttctgtttctgcaaacgagcagcctgagagccgaggacacgaccgtttttctgactccagaaatcccagggtaggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10822 JY8QFUQ01BYSP9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10823 JY8QFUQ01DXDWF No results +10824 JY8QFUQ01A4U6K productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame - tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10825 JY8QFUQ01A0OJJ productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 285 82.35 70/85 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame + Low V-REGION identity (82,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +10826 JY8QFUQ01C15UA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 926 92.56 199/215 nt 92.09 198/215 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.16.38.11] CARFGPLTRPDY## out-of-frame + in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) tctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +10827 JY8QFUQ01B4DKB unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 814 97.65 166/170 nt 8 7 X 8.7.X [1.17.23.X] null + No rearrangement found ctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttc +10828 JY8QFUQ01DKNML productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10829 JY8QFUQ01C6HZC No results +10830 JY8QFUQ01CJ8L9 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 8 13 8.8.13 [1.17.38.11] CATYGRFSFSPLDYW in-frame + gtctggattcgacttcagtagttatggcttccattgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctccccttgactactggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgagaacgtggtcatcgcctgcctggtccagggcttcttccccc +10831 JY8QFUQ01AOWLX productive (see comment) Homsap IGHV1-3*01 F 966 94.86 203/214 nt 94.39 202/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.37.11] CARWNNDLDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 83 of V-REGION: 1 nucleotides (from position 152 in the user submitted sequence), (cause frameshift) ctggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatcgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10832 JY8QFUQ01DFL6S productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1031 97.25 212/218 nt 96.79 211/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); cgtctggattcaccgtcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgGaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10833 JY8QFUQ01CRL0P productive Homsap IGHV3-7*01 F (see comment) 783 84.79 184/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARERSAAGVVFFDFW in-frame - Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaggggctggagtgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgcaaatgaacagcctgcgagtcgaggacacggctgtgtatttctgtgcgagagagagatcagcagctggagtcgtcttctttgacttttggggccagggagccccggtcaccgtctccagagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10834 JY8QFUQ01ABJSU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10835 JY8QFUQ01CH45V No results +10836 JY8QFUQ01B1QAD No results +10837 JY8QFUQ01B0JM4 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10838 JY8QFUQ01A3TN3 unproductive (see comment) Homsap IGHV4-61*02 F (see comment) 699 80.0 176/220 nt Homsap IGHJ4*02 F (see comment) 123 72.92 35/48 nt Homsap IGHD3-10*01 F 1 10 7 X 10.7.X [1.17.38.11] CARERGTTVGGASE#FDSW out-of-frame + stop codons Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gtctggtggccccgtcattattgatggttattactggacgtggatccgtcagcccgccgggaagggactggagtgggtcggacgtgtcaccagtcgtggggagaccaattacagttcctccctcaagagtcgaattttcatgtcagtagacacgtctaagaatcaattctccctgaggtttaattctgtgaccgccgcagacacggccctatattactgtgcgagagaacgcggtactacagttggcggggcgagcgaattttgactcctggggccagggagtgcaggtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +10839 JY8QFUQ01CNGUC No results +10840 JY8QFUQ01DOO1G No results +10841 JY8QFUQ01BOIQ7 productive (see comment) Homsap IGHV3-11*01 F 823 87.04 188/216 nt 86.57 187/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.16.38.11] CVTRRLGSTYTTFDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcactgactactacatgaattggatccgccaggctccggggaagggctggaatgggtttcatacattggaaccgatgatcaaaccagattttacgcagactctgtgaagggccgattcaccatctccacggacaacgcccagaattctgtgtttttgcaaatgaccagcctgcgagccgaggacacggccatgtattactgtgtgacacgtcgactgggaagtacctatacgacttttgatttttggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10842 JY8QFUQ01A5VM1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10843 JY8QFUQ01A4JG3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcaccagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactca +10844 JY8QFUQ01AV3VG productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 7 8 15 7.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) ttctggattcagtcctaccgattttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaa +10845 JY8QFUQ01BGINF unproductive Homsap IGHV3-7*03 F (see comment) 374 82.73 91/110 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD4-11*01 ORF 3 X X X X.X.X [X.X.36.11] CARDRYSSDSSYYMPNWLD#PW out-of-frame + Low V-REGION identity (82,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacgtttgggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgaccccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10846 JY8QFUQ01CZ3ME No results +10847 JY8QFUQ01BAKET productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 981 94.93 206/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 88 64.0 32/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDFW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaagggactggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggaagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +10848 JY8QFUQ01BQQBC productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10849 JY8QFUQ01AOTBL unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKQKS*LW#YYFDQW out-of-frame + stop codons ctctggattcacgtttaaaacacatgccatgagctgggtccgccaggctccaggaaaggggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaaatcatagttatggatactactttgaccagtggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10850 JY8QFUQ01AON9Y unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 746 83.26 179/215 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDKVISAGRDV## out-of-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AON9Y ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagtttcactggttttaccgtgatctgggtccgccaggctccaaggaaggggctggaatggatctcatccgtcactactaatggtctcacgtactacgcagactcagtagagggccgattcaacatctccagggacaacgccaacaatttagtgtttctgcaaatgaacagcctgagagtcgaggacactggtgtatattattgtgcgagagataaagtgatctctgccggacgggacgtctggggcccaagggaccacggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10851 JY8QFUQ01AUW74 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 789 86.26 182/211 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 7 8 9 7.8.9 [X.17.38.11] CTGLTYPDDYW in-frame + atttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggcctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10852 JY8QFUQ01AMEYY No results +10853 JY8QFUQ01A8A4C productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-20*01 F 1 8 8 14 8.8.14 [1.17.37.11] CARGLTTMTGNGLEHW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 169 in the user submitted sequence), (cause frameshift) tctctggattcacccttcgcagatatggcatggcgtgggtccgccaggctccggggaaggggctggagtgggtctcatcttctaacagtagtgatgaatccacatactatgcagactccgtgaagggccgcttcaccatttccagagaccattccaagaacacggtgttttgcaaatgtacagcctgagagccgaagacacggccctctattactgtgcgagagggctaacaacaatgacagggaatggtcttgagcactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10854 JY8QFUQ01B0WNX unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 133 63.64 49/77 nt 8 X X 8.X.X [1.16.X.X] null + No rearrangement found tctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +10855 JY8QFUQ01DXF20 unproductive Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [0.17.38.11] CARGPVSG#YTDYW out-of-frame + in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctgtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10856 JY8QFUQ01AF35K productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKVSGNSRTYWYLDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); gttctggatacaactttcccagatattggatcgcctCgggtgcgccagattcccgggagaggcctggagtgggtggggatgatctatcctggtgactctgagaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacgcgtccatgaacaccgcctacctgcagtggagcagcctgaaggcctccgacaccgccatatacttctgtgcgaaggtctctggtaactctcgaacctactggtacctcgatatctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10857 JY8QFUQ01C1Z2H productive (see comment) Homsap IGHV3-7*02 F 928 91.78 201/219 nt 90.41 198/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [2.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'CC' (2 nucleotides at position 13 to 14 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcCCatttttagaacctCattggatgagttgggtccgccaggctccagggaAaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10858 JY8QFUQ01AU76E productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +10859 JY8QFUQ01CF6EU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.37.11] CAKDGARGGGSCFNSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 177 in the user submitted sequence), (cause frameshift) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10860 JY8QFUQ01AF52M unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARADDYGDYP#EFW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactacccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +10861 JY8QFUQ01AOATE unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 267 62.42 103/165 nt 8 10 X 8.10.X [1.17.20.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (10 AA in JY8QFUQ01AOATE ; 8 AA in Homsap_IGHV3-7*01), and low V-REGION identity (62,42% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcactttcactaacgcctggatgagctgggtccgccaggctccagggaaggggctggagtggattggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10862 JY8QFUQ01BUHUI No results +10863 JY8QFUQ01CWJTG unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 427 88.79 95/107 nt 85.98 92/107 nt 7 8 X 7.8.X [2.16.1.X] null - No rearrangement found in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) cctctgggattcaccttcagtagctatagatgaactggtccgcccagctccagggaaggggctggagtggtctcatacattagtaggagtagtactgacatatacta +10864 JY8QFUQ01CECME No results +10865 JY8QFUQ01CNEDF productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame + ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10866 JY8QFUQ01DDQ8A productive (see comment) Homsap IGHV3-7*02 F 960 93.18 205/220 nt 92.27 203/220 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'A' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'CT' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift); agcctctacattcacgtttagtcggtattggatgagctgggtAccgccaggctccaggggaagggcCTgggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10867 JY8QFUQ01DSCVL No results +10868 JY8QFUQ01CZJGN No results +10869 JY8QFUQ01BKWM8 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANYW# out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccaggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10870 JY8QFUQ01BKF2J productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 712 80.82 177/219 nt 80.37 176/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [2.17.38.11] CARYRVGDSLYYGLDGW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 59 of V-REGION: 'ACT' (3 nucleotides at position 91 to 93 in the user submitted sequence), (do not cause frameshift); gcctctggattcattttagaaaattttgccatgagttggctccgccaggcaccagggaaggggctggaatgggtctcgactatcagcagcACTagtggtgacacggcatattactcagactccgtgaggggccgcttttccatctccagagacaactccaagagcactctgttcttgcagatgaacagcctgagtgccgaagacacggccatttactactgtgcgagataccgtgtgggtgacagtctctactacggtttggacggctggggccaagggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10871 JY8QFUQ01AKFEZ unknown (see comment) Homsap IGHV4-61*02 F 910 90.87 199/219 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctggtgactccatcaccagtggtaattattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggatcaccaactacaatccctccctcaagagtcgagtcaccatactattagacacgtccagcaaccggttctccctgaagctcagctctgtgaccgccgcagacacggccgtgtattactgtgcgagagaaaagtagtgatccgtcccaattggttcgacccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10872 JY8QFUQ01BHLSH productive Homsap IGHV3-7*01 F 964 93.61 205/219 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [2.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10873 JY8QFUQ01A1X35 productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 911 90.5 200/221 nt Homsap IGHJ4*02 F (see comment) 231 97.92 47/48 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARDRLGSCSGASCPVYYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctccatcaacagtggtgattcctcctggacctggatccgccagtacccagggaagggcctggagtggattgggtacatctctggcagtggggactcctactccaacccggccctcaagagtcgagttaccatatcagtggacacgtctaagagccagttcttcctggaactgagttctgtgactgccgcggacacggccgtctattactgtgcgagagatcggctgggatcttgtagtggggctagctgccccgtctactactttgactcctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccg +10874 JY8QFUQ01DE2O2 unproductive (see comment) Homsap IGHV4-61*02 F 902 90.05 199/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD2-15*01 F 1 10 7 X 10.7.X [1.17.38.11] CAREKG**SV#NWFDPW out-of-frame + stop codons tctctggtgactccatcaccagtggtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaatccctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagagaaaaaggctagtgatccgtcccaactggttcgacccctggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10875 JY8QFUQ01A4MMY unproductive (see comment) Homsap IGHV3-48*04 F 972 94.47 205/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDSRAGGYPNGILLLLWSGRL# out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatgggatacttctattactctggtctggacgtctgggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10876 JY8QFUQ01CB7M9 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1060 100.0 213/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - tctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10877 JY8QFUQ01COI40 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGSGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggtccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10878 JY8QFUQ01AFKMW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-3*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDVQFLEWSLPPLDYW in-frame + cctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgcgagccgaggacacggctgtgtattactgtgcgagagatgtccaatttttggagtggtcattaccacccttagactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10879 JY8QFUQ01AL8T2 productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10880 JY8QFUQ01A9M1O productive Homsap IGHV4-4*07 F (see comment) 557 73.49 158/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARVRDAYTAGHFDSW in-frame + Low V-REGION identity (73,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgactctgtcactatgtcttattgggcctggatacgtcagcccgccgggggaggcctggagttaattggacgaacttctgccagtccaaaagttacctacaatccctccctcaggagtcgagccaccatattcgaagacacttcaaagaatcaacttatcttgaaattggcctctgtgaccgccgcggacacggccatctactactgtgcgagggtccgtgatgcctacaccgctggacactttgactcctggggcccgggaaccctggtcaccgtctcttcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctgggtccacggggnttcttcccccag +10881 JY8QFUQ01CU33R No results +10882 JY8QFUQ01DCLUF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10883 JY8QFUQ01A4PSY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 897 90.0 198/220 nt 89.55 197/220 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 15 8.8.15 [2.17.38.11] CAKNRGSAMADWYFDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'ATG' (3 nucleotides at position 90 to 92 in the user submitted sequence), (do not cause frameshift); agcctctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattactaATGgtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttatttctgtgcgaaaaatagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10884 JY8QFUQ01A02L1 unproductive (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F (see comment) 408 80.65 100/124 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 X 3 X X.3.X [X.X.38.11] CASFAGPVVVTL*WLLVRLT#YCDYR out-of-frame + stop codons Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctgcattcaccgtcagtaggctccgtgacgggccgagtcatcatctccagagagaatgcccagaactccgtgtatcttccactgaacagcctgagagccgggaacacggctgtgtatcactgcgcaagttttgctggccctgtggtggtgactctatagtggctgttggtccgtctgaccactactgtgactaccggggcctgggaaccccggtccccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10885 JY8QFUQ01AKXI3 No results +10886 JY8QFUQ01BH47R No results +10887 JY8QFUQ01APBLB productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 191 86.0 43/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDXFDTW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacncttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10888 JY8QFUQ01ARLVF productive Homsap IGHV3-7*01 F 837 87.56 190/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CGRDERGADLPNDSW in-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagccccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctggggcctgggaaccctggtcaccgtctcctcaccatcccctgacccagccccaaggtcttccgctgcagctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10889 JY8QFUQ01AHUH3 unproductive (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F (see comment) 413 80.8 101/125 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 X 3 X X.3.X [X.X.38.11] CASFAGPVVVTL*WLLVRLT#YCDYR out-of-frame + stop codons Low V-REGION identity (80,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgcattcaccgtcagtaggctccgtgacgggccgagtcatcatctccagagagaatgcccagaactccgtgtatcttccactgaacagcctgagagccgggaacacggctgtgtatcactgcgcaagttttgctggccctgtggtggtgactctatagtggctgttggtccgtctgaccactactgtgactaccggggcctgggaaccccggtccccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactca +10890 JY8QFUQ01DA7QX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 2 8 8 9 8.8.9 [1.17.38.11] CARDNYGDYWG in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaacccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10891 JY8QFUQ01DIHNN unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDPGNYWGYYYDS## out-of-frame + gtctggattcacctttagtgattatgccttgagctgggtccgccagactcccgggaaggggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgagagatccgggaaattattggggatactattatgactcttgggggcctgggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +10892 JY8QFUQ01AKX15 productive Homsap IGHV3-7*03 F 886 90.28 195/216 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame + tctggattcacctttagtagttattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10893 JY8QFUQ01DAACI productive Homsap IGHV3-74*03 F 856 88.13 193/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARGTNAVLADPMDYW in-frame - gcctctggattcacctttagtgactactggatgcactgggtccgccaagttccagggaaggggctggtttgggtctcacgcattaaaactgatgacacatctataacgtacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaatacgttgtttctgcaaatgaacgatctgagagttgacgacacggcggtgtattattgtgcaagagggacgaacgctgttctggctgaccccatggactattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10894 JY8QFUQ01A35H8 No results +10895 JY8QFUQ01CTZBP productive Homsap IGHV4-39*02 F 921 90.58 202/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 3 10 7 14 10.7.14 [2.17.38.11] CARPGARETNNAWVDW in-frame - tctctctggtggctccgtcagtaggagtgcctactactggggctggatccgccagcccccagggaaggggctggagtggattgggaccatctattatagtgggaccacatactccaatccgtccctcaagactcgagtcaccatgtccttggacacgtccaagaaccacatctccctgaagctgaattctgtgaccgccgcagacacggctgtttattactgtgcgagacctggggctagggagactaataacgcctgggtcgactggggccagggcaccctggtcaccgtctcctcggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10896 JY8QFUQ01CFF78 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10897 JY8QFUQ01AJASK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10898 JY8QFUQ01C0BE5 productive Homsap IGHV4-34*10 F 818 86.98 187/215 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame + tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggcccaagggaacccgtggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10899 JY8QFUQ01B5JSV productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10900 JY8QFUQ01A4O1N unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 909 91.24 198/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 97 66.0 33/50 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CARRDVGLHAFDL## out-of-frame + ttctggatccaattttaactacgactggatcggctgggtgcgccagatgcccggtaaaggcctggagtggatgggaatggtctatgttggtgactctgatgctagatacagcccgtcctcccaaggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattattgtgcgagacgggacgtaggtttacatgcttttgatctgtggggcccaggggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10901 JY8QFUQ01CBET4 productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 869 86.78 197/227 nt 86.34 196/227 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*02 F 2 8 10 12 8.10.12 [2.17.38.11] CSYFRHEPYHFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tagacgctggattcgcctctggtgattatgctatgagttggttccgccaggctccgggaaAaggggctggagtgggtggggttcatcagaagcagagcttacactgggacaccagaatacgccgcgtctgtgaaaggcagattcaccatctccagagatgcttccaaaagtattggctatctgcaaatgaacaatctgaggatcgaggacacagccgtctattattgctcttattttcggcatgagccatatcactttgactattggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10902 JY8QFUQ01CVT72 unproductive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CARERGNSYGEIDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggcccaagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10903 JY8QFUQ01BO0WM No results +10904 JY8QFUQ01BMY9S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKGLGPRYYYYGLDVW in-frame + cctcggaattctccgtcagtgacagtcacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatctattgatggtcgggctactaccccatatcacgcagagtccgtgaagggccggttcaccatctccagagacaattccaacaacacactgtatctgcaaatgaacagcctgagagccgaggacgcggccgtctattattgtgcgaaaggattggggcctcggtattattactacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10905 JY8QFUQ01BRADB No results +10906 JY8QFUQ01A0939 productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 985 93.33 210/225 nt 92.89 209/225 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 10 9 19 10.9.19 [1.17.38.11] CARGSSRGGNSDGVYYELDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctaccacccgtgctgcttggaactggatcaggcagtccccatcgggaggccttgagtggctggGgaaggacatactacaggtccaagtggcttaatgattatgcagtgtctgtgaaaagtcgaattaccatcaatccagacacatccaagaaccagttttccctgcagttgaaatctgtcattcccgaggacacggctgtttattactgtgcaagaggttccagtcgcggggggaattctgatggggtctactatgaacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +10907 JY8QFUQ01DLKIA productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 696 80.84 173/214 nt Homsap IGHJ2*01 F 112 67.92 36/53 nt Homsap IGHD3-16*01 F 3 8 7 10 8.7.10 [1.17.38.11] CARLDGALRSLG in-frame + Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacggggcacttcgatctctgggggcccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10908 JY8QFUQ01A1IYG productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10909 JY8QFUQ01B8OAF No results +10910 JY8QFUQ01CJCGS No results +10911 JY8QFUQ01CHCVN No results +10912 JY8QFUQ01BO5DQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - gcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10913 JY8QFUQ01C97XU productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10914 JY8QFUQ01CPGIE unproductive (see comment) Homsap IGHV1-69*08 F 911 92.45 196/212 nt 91.51 194/212 nt Homsap IGHJ4*03 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 14 8.8.14 [0.16.38.11] CARDSNGYSSGYIDCW in-frame - stop codons in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 2 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) tggaggctccttcggcagctacactatcacctgggtgcgacaggccctgacaagggcttgagtggatggGgaaggatcacccctatccttggttcaacaagctactcacagaagttccagggcagagtcacgattaccgcggacacattcacgggcacagcctacatggagctgagcagcctgacatctgaagacacggccgtatattactgtgcgcgagactcgaatggatacagttctggttatattgactgctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt +10915 JY8QFUQ01B7HV5 productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10916 JY8QFUQ01B8S9W productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVKGAGTTVNWFDIW in-frame - cctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10917 JY8QFUQ01AFSB1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDFW in-frame + cctctggattcacctttagcaactttgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10918 JY8QFUQ01AVEBS productive (see comment) Homsap IGHV3-11*01 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10919 JY8QFUQ01BLH4H unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDY## out-of-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggcccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10920 JY8QFUQ01BCQ7F productive Homsap IGHV3-7*01 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARERSAAGVVFFDFW in-frame - Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaggggctggagtgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgcaaatgaacagcctgcgagtcgaggacacggctgtgtatttctgtgcgagagagagatcagcagctggagtcgtcttctttgacttttggggccagggagccccggtcaccgtctccagagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10921 JY8QFUQ01DI568 No results +10922 JY8QFUQ01CD5BR unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 146 53.26 98/184 nt 52.72 97/184 nt 8 8 X 8.8.X [1.16.27.X] null + No rearrangement found in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagttactggatgaactgggtccgccaagctccagggaagggctggtatgggtctcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +10923 JY8QFUQ01CBORW productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSGSSDYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); cctctggattcagttttagttcttatggcatgaactgggtccgccaggctccatggggggggctggagtgggtctcattcattaacagtgttagtagttacaaatactatgtggacccagtgaGggggccgattcaccatctccagagacaacgccaagaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagatagcggctcgtccgactacactaggtacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10924 JY8QFUQ01B526Q productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt 99.55 219/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10925 JY8QFUQ01AYG87 productive (see comment) Homsap IGHV3-30*01 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.37.11] CARGTMLRGVTKARYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 209 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10926 JY8QFUQ01BYHU2 unproductive Homsap IGHV3-48*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F (see comment) 103 62.9 39/62 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CARARRTISGVVFIEHYGYD#W out-of-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcaggacccatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcattcattagtagtagtagtggtaccatattttatgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactttatctgcaaatgaacagcctgagagacgaggatgcggctgtgtattactgtgcgagagcccgtaggacgatttctggagtggtttttattgagcactacgggtatgactctggggcccagggaccacggtctccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +10927 JY8QFUQ01AIE5M productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgcctgctccaggagcaccctccgagagcacagcggccctgggctgcctggtcaaggactcacttccccgaaccgtgacggtgtcgtggaactcagg +10928 JY8QFUQ01B9WE3 unproductive Homsap IGHV3-74*03 F 1031 97.25 212/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD2-8*01 F 1 8 8 X 8.8.X [1.17.38.11] CATGPDYAYAM## out-of-frame + cctctggattcaccttcagtcgctactggatgcactgggtccgccaagctccagggaagggcctggtgtgggtctcacgtattaaaagtgatgggattagcacaacgtacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtactactgtgcaaccgggcccgattatgcgtatgctatgtggggtccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa +10929 JY8QFUQ01C9CX6 unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10930 JY8QFUQ01A1DDW productive (see comment) Homsap IGHV4-59*02 F 895 90.74 196/216 nt 89.81 194/216 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 8 7 15 8.7.15 [2.17.38.11] CARGGSGGSYWNLIRDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'TGGTCGC' (7 nucleotides at position 24 to 30 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'A' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); gtctctgatgactccgtcagcagTGGTCGCttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctAccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +10931 JY8QFUQ01B51BA No results +10932 JY8QFUQ01ANYII productive (see comment) Homsap IGHV1-2*02 F 790 85.51 183/214 nt 85.05 182/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDWGGTYAPLDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); tggatacattttcaccgGgctactatttacactgggngcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaaccttgaccagtgacacgtccatcagtacagcctacatggaaatgagcgggctgacgtctgaggacacggccatcttttactgtgcgagagattggggtggcacgtacgctccgcttgacaattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10933 JY8QFUQ01CYFJ0 No results +10934 JY8QFUQ01DB9MD unknown (see comment) Homsap IGHV3-7*01 F 1041 96.82 213/220 nt 96.36 212/220 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10935 JY8QFUQ01B8BDH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccagccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactc +10936 JY8QFUQ01BK7H0 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 185 100.0 37/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcaccttcagtgactactacatgaactgg +10937 JY8QFUQ01CW0ZP No results +10938 JY8QFUQ01AQGFK productive (see comment) Homsap IGHV3-7*01 F 952 94.37 201/213 nt 93.43 199/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [0.17.37.11] CAISSAYFSTGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 165 in the user submitted sequence), (cause frameshift) tggattcacctttagtaaccattggatgagttgggtccgccaagctccagggaaggGggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10939 JY8QFUQ01ANO3L productive (see comment) Homsap IGHV4-4*07 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 2 8 7 11 8.7.11 [2.17.38.11] CAARNGNVAFNIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 27 of V-REGION: 'C' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); gtctctggCgggctccatctatagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgaatctattccagtggggacaccaactacaacccctccctcaagagtcgagtcaccatgtcagtggacaagtccaagaaccagttctccctgaagctgaagtctgtgaccgccgcggacacggccgtgtattactgtgcggcgagaaatggaaatgtggcttttaatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10940 JY8QFUQ01A6KQQ productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10941 JY8QFUQ01AD65Y productive Homsap IGHV3-48*01 F 1085 100.0 218/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10942 JY8QFUQ01DKITI No results +10943 JY8QFUQ01BFWAR productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +10944 JY8QFUQ01A9VMG productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 861 88.18 194/220 nt 87.73 193/220 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVSDRELHYQHLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); agcgtctggattcaacttcaatagttTttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10945 JY8QFUQ01DCNOJ unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDRSGQAVGY## out-of-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaacccgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +10946 JY8QFUQ01B56O6 No results +10947 JY8QFUQ01ALTZA productive (see comment) Homsap IGHV3-66*02 F 912 92.06 197/214 nt 91.12 195/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.16.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcagtagcagcttcatgacttggtccgccaggctccaggaaaggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10948 JY8QFUQ01C344D productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [1.17.38.11] CSNGYGDFPRRW in-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gtctggattcaccttcaggagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgacaaattctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10949 JY8QFUQ01BD0GZ No results +10950 JY8QFUQ01C6LPJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10951 JY8QFUQ01BAUZA No results +10952 JY8QFUQ01DWYUU productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10953 JY8QFUQ01DOMGW unproductive (see comment) Homsap IGHV3-48*02 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [1.16.38.11] CARPAGAG*PFFA#YYSGLDVW out-of-frame + stop codons in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagttatagcatgaactggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggcagggtgacccttttttgccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10954 JY8QFUQ01AYR4C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARDILGATRFDYW in-frame + ctctggattcaccttcagcagctatgccatgagctgggtccgccaggctccagggaagggcctggagtgggtctcagctattagtggtattggtgggagtacattctacgcagactccgtgaagggccggttcaccatcaccagagacaattccaacaacacgctgtttctgcaaatgaatagcctgagagccgaggacacggccatatattactgtgcgagagatattctgggagctactcggtttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10955 JY8QFUQ01DQ5E1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10956 JY8QFUQ01B8YM6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + cctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10957 JY8QFUQ01BZ7D4 No results +10958 JY8QFUQ01B4T55 No results +10959 JY8QFUQ01A88F1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10960 JY8QFUQ01C69CS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 955 93.15 204/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - gcctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10961 JY8QFUQ01AV350 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 854 90.78 187/206 nt 89.81 185/206 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 9 nucleotides (from position 15 in the user submitted sequence), (do not cause frameshift) tctctggtgactctcacttctggagctggatccggcagcccccagggaagggcccggagtggattggttatgtctataacagtgGggaccaccaactacaacccctccctcaggagtcgagtcaccatttctatcgacacgtccaagaagcagatctccctgaagttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10962 JY8QFUQ01C5BUB productive (see comment) Homsap IGHV1-69*08 F 912 92.06 197/214 nt 91.12 195/214 nt Homsap IGHJ4*03 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARDSNGYSSGYIDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'GA' (2 nucleotides at position 73 to 74 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); tggaggctccttcggcagctacactatcacctgggtgcgacagggccctggacaagggcttgagtggatgggGAacggatcaCcccctatccttggttcaacaagctactcacagaagttccagggcagagtcacgattaccgcggacacattcacgggcacagcctacatggagctgagcagcctgacatctgaagacacggccgtatattactgtgcgcgagactcgaatggatacagttctggttatattgactgctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10963 JY8QFUQ01CG3IN productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 285 82.35 70/85 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame + Low V-REGION identity (82,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10964 JY8QFUQ01BJPU6 productive (see comment) Homsap IGHV3-11*01 F (see comment) 770 83.94 183/218 nt 83.49 182/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARVRCSGNTCGAFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); cctctggattcagcttaagtgactactacatgacctgggtccgccaggGccccagggaagggactggagtggctcgcctacattagtcgaactgatgattccgtatattccgcagagtctgtggtgggccgattcaccgtctccagggacaacgtccaaaactcactgtttttgcagatgattggcctgagagacgaggacacggccgtatattactgtgcgagagtccgctgtagtggtaatacctgcggggcttttgatttgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10965 JY8QFUQ01A6PTZ productive (see comment) Homsap IGHV3-11*04 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRDRLYDSSGYDFGELGDYSDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); ctctggattcaacttcagtgactactaGcatgacttgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtgctagtggtggtaccataaaatacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtttctgcaaatgaacagcctgagggccgaagacacggctgtatatttttgtgtgagagatcgtctctatgatagtagtggttatgactttggggaattgggggactattcagaccactggggccagggaacccaggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10966 JY8QFUQ01CAN38 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1071 99.54 216/217 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-2*03 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFD#PW out-of-frame + ctctggattcacttttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +10967 JY8QFUQ01DNV7F productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKEEFDTGWTQPGDW in-frame + ctctggattcaccttcagtagccatgctatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacgctatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10968 JY8QFUQ01AF9TM unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt 91.24 198/217 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-3*01 F 2 7 8 X 7.8.X [1.17.38.11] CARGGLEPVDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 42 of V-REGION: 'GT' (2 nucleotides at position 39 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) cctctggattcaccttagtacatactggatgcactgggGTccgcccaagctccagggaaggGggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10969 JY8QFUQ01C5M5K unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 351 62.21 135/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (62,21% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ttctggattctcctttagcaactatgccctggcctgggtccgccaggctccagggaaggggctggagtgggtctcaattgttagtggaagtggtactggcacaggccacgcagactccgtatattactgtgcgaaggatatgggtggcgactattacatctttcactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10970 JY8QFUQ01DIDA9 No results +10971 JY8QFUQ01B17HS productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDPRSVSRYSLFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagtgactattggatgagctgggtccgccaggctccagggaaggggctagagtgggtggccaacataaatagagatggaagtgagcaacactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacatggctatgtatttttgtgcgagagatcctcgttccgtgagcagatactctttatttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10972 JY8QFUQ01B7D6Q productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 894 91.12 195/214 nt 90.65 194/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-18*01 F 1 8 8 15 8.8.15 [0.17.38.11] CAIVDTNLVSATGKDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcagcaactactatagacactgggtgcgacaggCcccctggacaagggcttgagtggatgggaatgatcaaccctagtagtgattacaaatattacgcacagaaatttcagggcagagtcaccatgaccagggacacgtccacgagcacagtcttcatggagctgagtagcctgagatctgacgacacggccgtgtattattgtgcaatagtggacacaaatttggtttcggcgaccggtaaagactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10973 JY8QFUQ01BABPJ No results +10974 JY8QFUQ01ARYXD productive Homsap IGHV4-39*03 F 929 91.36 201/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10975 JY8QFUQ01AJ6O8 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 750 83.64 179/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 X 8.7.X [1.17.38.11] CARGPGITTV#DAFDVW out-of-frame + Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgaggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10976 JY8QFUQ01CHVQB No results +10977 JY8QFUQ01CHX0H productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*04 F 993 96.26 206/214 nt 95.79 205/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-15*01 F 2 8 7 21 8.7.21 [1.16.38.11] CARRIQGHCRGGSCSRNNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tctatggtgggtccttcagtggttactactggagttggatccgccagccccagggaaggggctggagtggattggggaaatcaatcatagtggaagcaccaactacaactcgtccctcaagagtcgagccaccatctcagtagacacgtccaagaagcagttgtccctgaacgtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacggattcaaggacattgtaggggtggtagttgctccaggaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10978 JY8QFUQ01DUOGR No results +10979 JY8QFUQ01C3PLL unknown (see comment) Homsap IGHV3-30*15 F 896 90.37 197/218 nt 89.91 196/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); tctccggattcacctttagtaaatattccatgaactgggtccgccaggctccaggcaaggggctcgagtgggtggcacttatatcatacgatggaagtaGaaaaaatctacgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactacttttgactattgggggccagggaaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccaggag +10980 JY8QFUQ01DLLPI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CAKDRVLSGGPDYW in-frame + ctctggattcatctttagcaattttgccatgaactgggtccgccaggctccagggaaggggctggagtgggtcgcaagtatcagtcgttacggtggaagctcaaaccacgcagactccgtcaagggccggttcaccatttccagagacaatggcatgaacacgctgtttcttcaaatgaacagcctgagagccgaggacacggccatatactactgtgcgaaagatcgagtcttaagtgggggccctgactactggggccagggagtcctggtcaccgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +10981 JY8QFUQ01DAX0I productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10982 JY8QFUQ01DO1JM unknown (see comment) Homsap IGHV4-61*02 F 884 89.14 197/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttcggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10983 JY8QFUQ01BVU4U No results +10984 JY8QFUQ01DMXRX unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*05 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*07 F or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69*14 F or Homsap IGHV1-69D*01 F (see comment) 413 73.12 117/160 nt 71.25 114/160 nt 7 8 X 7.8.X [X.15.22.X] null - No rearrangement found Low V-REGION identity (73,12% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 56 of V-REGION: 'GA' (2 nucleotides at position 71 to 72 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 44 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 55 of V-REGION: 3 nucleotides (from position 70 in the user submitted sequence), (do not cause frameshift) aggcaccttcagtagttacgcaatcagctgggtgcgacaggccctgggcaagggcttgagtggatgggggGAtcatccctaagtttggaagaacaaactacgcacagagtttccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10985 JY8QFUQ01AI30F No results +10986 JY8QFUQ01DKKST productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacactgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10987 JY8QFUQ01CWQNK productive Homsap IGHV1-3*01 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDGESLGGDYFDYW in-frame + tggatacaccttcagtaattatgctatacattggttgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctggcacgggtaacacaaaatattcacagaagttccagggcagagtcaccattaccagggacacagccgcgaccacagcctacatggaattgagcagcctgaaatctgaggacacggccgtgtattactgtgcgagagatggggagtcactgggaggcgactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +10988 JY8QFUQ01BAZT3 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + gtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10989 JY8QFUQ01DO347 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDREDSSGYYFFRDGFDIW in-frame + ctctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctccggtattggtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagatcgtgaagatagtagtggttattacttcttccgtgatggttttgatatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +10990 JY8QFUQ01BL0EE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +10991 JY8QFUQ01AC7OR productive Homsap IGHV3-74*03 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + cctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +10992 JY8QFUQ01AH7MF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame - ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10993 JY8QFUQ01AZ8UY unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 817 87.32 186/213 nt 86.85 185/213 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 6 X 8.6.X [1.17.38.11] CAREKGSGPPH#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttcttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10994 JY8QFUQ01BH3GK productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtacttactactggacatGggatccgccaggcacccagagaaggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +10995 JY8QFUQ01DEJ3A productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +10996 JY8QFUQ01B06AQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - agcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10997 JY8QFUQ01BNY8P productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +10998 JY8QFUQ01A00NG unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 125 100.0 25/25 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found tccggggacagtgtctctagcaaca +10999 JY8QFUQ01CIPYX productive Homsap IGHV3-7*03 F 945 93.09 202/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVRYDYSRLHRSNYFGPW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11000 JY8QFUQ01CCEYG productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.16.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccaggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +11001 JY8QFUQ01DQFDK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + tctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11002 JY8QFUQ01C5QUT unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 454 72.63 130/179 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (72,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11003 JY8QFUQ01BWZC8 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 817 85.59 190/222 nt 85.14 189/222 nt Homsap IGHJ3*01 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-16*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARTYTYRNAFDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 34 of V-REGION: 'ACC' (3 nucleotides at position 22 to 24 in the user submitted sequence), (do not cause frameshift); gtctttggtgactctctgagtACCagtagcagtttctactggggctgggtccgccaggccccagggaagggactggagtgggttgggactgtttattatagtgggagcgcccactacaatccgtccctcaagagtcgagtcgccatatccgtggacacggcccaaaaccaggtctccctgactttgaactctgtgaccgccgcagacgccgctgtctatttctgtgcgagaacttatacttatagaaatgcttttgacgtctggggccaggggacattggtcgctgtgtcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11004 JY8QFUQ01BXP0X No results +11005 JY8QFUQ01BBXYO productive Homsap IGHV1-2*02 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 2 8 8 15 8.8.15 [0.17.38.11] CAKVSSTRTAGLYFDYW in-frame - tggatacaccttcaccggctcctatatgcactgggtgcgacaggcccctggacaaggccttgagtacataggatggatcaaccttaacagtgctggcacaaattatgtacagaggtttcagggcagggtcaccatgaccagggacacgtccattaccacagcctacatggagctgagccggctgacatctgacgacacggccgtgtattactgtgcgaaagtatcctcgacaagaacagctggcctttactttgattactggggccagggaaccctggtcaccgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11006 JY8QFUQ01A14J8 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*03 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*11 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 915 90.91 200/220 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD5-18*01 F 1 8 8 15 8.8.15 [2.17.38.11] CARGKDTGMGSHGMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctgctggattcaccttcactaatcatcgtatgcactgggtccgccaggctccaggcaaggggctagagggggtggcagttatttcatatgatggaaggaataaatactatgcagactccgtgaagggccgattcaccatctccagagaaaattccaacaaaacgttatatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgagaggaaaggatacaggtatgggttcgcacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11007 JY8QFUQ01DHSA2 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1022 96.79 211/218 nt 95.87 209/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 7 11 8.7.11 [2.16.38.11] CVVQILGATIDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 63 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 83 in the user submitted sequence), (cause frameshift) ggcctctggattcaccttcaatacctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccatagtagtggtagtacttacataaagtacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtggtccagatcctaggggctacgattgactactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11008 JY8QFUQ01DJR2Q productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame - tctggattcacctttagcatctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcgactattagtggtagtggaaatagtacataccatgcagactccatgaagggccggttcaccctctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11009 JY8QFUQ01CK8EK No results +11010 JY8QFUQ01A7KXL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11011 JY8QFUQ01B312C productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARAGYCNNGVCYSSYFDFW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccggggaaggggctggtgtgggtctcacgtatgaatagtgatggcagtgacataaggtacgcggactccgtgaggggccgattcaccatctccagagacaacaccaagaacacgctgtatctacaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagcgggatattgtaataatggtgtatgctactccagttactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +11012 JY8QFUQ01CXKUT unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYFGTL#DYW out-of-frame + stop codons gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttggaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11013 JY8QFUQ01C3QFI unproductive Homsap IGHV3-30*04 F, or Homsap IGHV3-30-3*03 F 868 89.35 193/216 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-11*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CSSGGDYPN## out-of-frame - tctggattcgacttcgatggccgtgctatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatctcatatgatggaaatgataaaaactacgcagactccgtgaggggccgattcaccatctccagagacaattctaaggacacgctgtttttgcaaatgaacagcctgagacatgaagacacgggtgaatatttctgttcttcaggaggtgactacccgaactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +11014 JY8QFUQ01C13BC unproductive Homsap IGHV3-7*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + ctctggatttacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +11015 JY8QFUQ01BGAKE productive Homsap IGHV3-48*01 F 923 91.74 200/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGNYYYFGMDVW in-frame + cctctggattcctcttcagtagctttaacatgaactgggtccgccaggttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccatctactactgtgcgagacaaactgggaattattattacttcggtatggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11016 JY8QFUQ01AELH5 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 929 91.4 202/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 10 7 X 10.7.X [1.17.38.11] CARRALDSSGHYIDI## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatgagcagtggtaattactgctggggctggggccgccagcccccaggaaaggggctggagtggattggaagtatgtgttatggtgggagcacctactacagcttgtcccccaagggtcgagtcaccatatccatagactcgtcgaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagacgcgcattagacagtagtggtcattacattgacatctgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +11017 JY8QFUQ01CL3FT unproductive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 830 86.43 191/221 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 3 10 7 X 10.7.X [1.17.38.11] CARAGGWT#YFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctccgtcaacagtggtaattactactggaactggatccgccaatccccagggaagggactggagtggattggatatatctactatgctggggccaccaacctcgccccctccctcaagaaccgagtcaccatatcgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccatatattactgtgcgagggccggtggctggacccctactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11018 JY8QFUQ01AOEER productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 847 87.67 192/219 nt 86.3 189/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) cctccgggagttcaccttagtagtttctggatgcactgGggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatGagtatggggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11019 JY8QFUQ01AKI3P productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 803 85.07 188/221 nt 84.16 186/221 nt Homsap IGHJ6*02 F (see comment) 188 78.69 48/61 nt Homsap IGHD1-14*01 ORF 2 10 7 12 10.7.12 [1.17.38.11] CTRQGPYLYGFDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'T' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); tctctggtgtttccgtcagtaacactGattttctattggggTctgggtccgccagtccccagggaagggactggagtggattggcagtgtagattatagtgggagcgcttcctacagccctgccctcaagagtcgagtcatcatatccatagacacgtccaagaaccagttctccatagctctgagttctgtgaccgccgcagacacggctgtctattattgtacgagacagggaccctacctctacggtttcgacgtctggggccaagggaccacggtcaccgcctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +11020 JY8QFUQ01DE6DM productive Homsap IGHV3-74*03 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11021 JY8QFUQ01DS7CO unproductive (see comment) Homsap IGHV3-9*01 F 460 90.99 101/111 nt 90.09 100/111 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 X 16 8.X.16 [2.15.11.11] CAKDGSAIPVTGTYFEYW in-frame - stop codons in FR2-IMGT, from codon 54 of V-REGION: 109 nucleotides (from position 78 in the user submitted sequence), (cause frameshift) agcctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggaatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11022 JY8QFUQ01BSOS8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11023 JY8QFUQ01BDIQ1 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 859 88.89 192/216 nt 87.96 190/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 35 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) gcctctggattcaccctttggttatatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11024 JY8QFUQ01DNPQB No results +11025 JY8QFUQ01A3R46 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 163 92.11 35/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found cctctggattcaccttcagtgactatcacatgtactgg +11026 JY8QFUQ01BB77N productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 155 to 155 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccGagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11027 JY8QFUQ01CR1LS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - ctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11028 JY8QFUQ01BN59C productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 783 84.79 184/217 nt 83.87 182/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD2-21*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARRSGRDGGWFDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 137 to 137 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'TC' (2 nucleotides at position 154 to 155 in the user submitted sequence), (cause frameshift); ctctggattcatctttgccgactatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtcgcagatattaatggaagaggtgctgccgcacactacgcagactccgtgacgggccgcttcaccCctctacaaagacggttTCcaaagaatacgatgtatctgcaaatgaggaccctgagagacgacgacacggccaaatattactgtgcgagacgaagtgggcgtgatgggggctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11029 JY8QFUQ01BA6L3 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 932 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11030 JY8QFUQ01DBPDU productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 860 88.53 193/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame + gttctggattcagtcctaccgatttttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggctcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +11031 JY8QFUQ01CJ93A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARGPRSRGYGMDVW in-frame - agcctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11032 JY8QFUQ01AMLRB No results +11033 JY8QFUQ01AMWF5 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 44 of V-REGION: 'T' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagttatagcatgaactgggtccgccTgggctccagGggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11034 JY8QFUQ01COCGB unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +11035 JY8QFUQ01C0SS1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame - cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11036 JY8QFUQ01B1N7G productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 867 87.44 195/223 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*02 F 2 8 10 12 8.10.12 [1.17.38.11] CSYFRHEPYHFDYW in-frame + cgctggattcgcctctggtgattatgctatgagttggttccgccaggctccgggaaaggggctggagtgggtggggttcatcagaagcagagcttacactgggacaccagaatacgccgcgtctgtgaaaggcagattcaccatctccagagatgcttccaaaagtattggctatctgcaaatgaacaatctgaggatcgaggacacagccgtctattattgctcttattttcggcatgagccatatcactttgactattggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11037 JY8QFUQ01AP2Y1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ4*01 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDGVRGVGAYYIYYFDLW in-frame + ctctggattcacctttggcctctatgccatgaactgggtccgccagactccagggaaggggctggagtggctcgcaactattagtggtagtggaagtagatcattttacgcagactccctgaagggccggttcaccatctccagagacaattccaagggcacggtatacctggaaatgaccaccctgagagccgaggacacggccgtatattactgtgcgagagatggggtccgtggcgttggtgcttactacatctactattttgacttatggggccaaggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11038 JY8QFUQ01BS9NH productive (see comment) Homsap IGHV4-39*03 F 924 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctccggtggctccatcaacagtagaaattattattggggctggatccgccagcCccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11039 JY8QFUQ01BU9BZ productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [2.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); gcttctgggttcaccgtcagtagcaagGttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11040 JY8QFUQ01ANERH productive Homsap IGHV3-30*15 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGPGGGWYAEQW in-frame + ctctggattcacctttagtagatattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttatatcatacgatggaagtagaagaatctacgcagactccgtgaagggccgattcaccatctccagagacacttccaagaacacggtgtatctgcaaatgagtagcctgagacctgaggacacggctgtgtattactgtgcgaaagatgggccggggggtggctggtacgctgagcagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11041 JY8QFUQ01BF786 No results +11042 JY8QFUQ01B7IID productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 931 92.59 200/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11043 JY8QFUQ01C9X3S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11044 JY8QFUQ01CPQ3H productive Homsap IGHV3-7*01 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-3*02 F 2 8 8 16 8.8.16 [2.17.38.11] CARQFRSGNTDYFGLDVW in-frame - cagcctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcaccatctccagagacaatgacaagaactcattgtatctgcaaatgaacagcctgagagccgaagacacggctgtgtattactgtgcgagacagtttcgtagtggtaatacagactacttcggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11045 JY8QFUQ01DMPJE unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 873 89.4 194/217 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] YAKDQSCIVGPCGFDY## out-of-frame + Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactatgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11046 JY8QFUQ01CPCDK productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-15*01 F 2 8 8 21 8.8.21 [1.17.37.11] CARDSGMFCNSGSCYVYYGPDLW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 157 in the user submitted sequence), (cause frameshift) ctctggattcttcttcagcagttttggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggcagtcacatcatatgatggaggtaataaattttatggagactcagcgaagggccgattcactatctccagagacaattccaaaacacactgtatctgcaaatgaacagactgacaactgaggacacggctacttattactgtgcgagagattcggggatgttttgtaacagtggtagttgctacgtctattacggcccggacctctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttc +11047 JY8QFUQ01DUXRT productive (see comment) Homsap IGHV4-39*03 F 922 92.09 198/215 nt 91.16 196/215 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 9 6 17 9.6.17 [0.17.38.11] CARSITLTVVVMNDAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 23 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 99 in the user submitted sequence), (cause frameshift) ccggtggctccatcaacagtagaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11048 JY8QFUQ01AVL1I unproductive Homsap IGHV4-59*03 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [1.17.38.11] CARYYFASGILTSGSFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaataattattactggggctggattcggcAaccccccagggaagggactggaatggattgggtatatccaccacagtgggagcaccaactacaatccctccctcaagagtcgattcaccatgttagtcgacacatcccagaatcaattctccctgaaattgaattccgtgaccgctgcagacacggccatatatcgctgtgcgagatattacttcgctagtggaattcttacgtcggggagctttgactactggggccagggaacccgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11049 JY8QFUQ01AKIEX productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 762 83.18 183/220 nt 82.73 182/220 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD3-3*01 F 2 10 7 12 10.7.12 [1.17.37.11] CARRWSGTYPFASW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 210 in the user submitted sequence), (cause frameshift) tctctggtggctcactcagaagtagtagtcaccattggggctggattcgtcagtcccccgggaaggggctggagtggcttgggactgtcgactttcgtgggaccacccactacaacccgtccctcatgggtcgactcacgatatccgtcgacgcgcccaagagtcaaatgtccctgcacttgagctctgtgaccgccgcagacacggcttttacttctgtgcgagacgctggagtgggacttatccgtttgcctcctggggccagggcatcccggtcatcgtctccccagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11050 JY8QFUQ01A7XVM No results +11051 JY8QFUQ01CMVR1 unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccagttttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11052 JY8QFUQ01CSJ98 productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11053 JY8QFUQ01A39TZ No results +11054 JY8QFUQ01BT5S9 productive Homsap IGHV4-39*02 F 983 94.12 208/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.17.38.11] CARIVVRQFDQW in-frame + tctctggtgactccatttccagtactagttattactggggctgggtccgccagcccccagggaaggggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11055 JY8QFUQ01APQ85 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame + ctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +11056 JY8QFUQ01C33ZE No results +11057 JY8QFUQ01AR7NH productive Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11058 JY8QFUQ01A30ZP No results +11059 JY8QFUQ01B6G9V productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASDLGGQKSYW in-frame + ctctgggttcaccttcagtaactcctggatgcactgggtccgccaagctccagggaaggggccggagtgggtctcacgtattaatagtgatgggagtaatacaatctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11060 JY8QFUQ01CG7RL unknown (see comment) Homsap IGHV3-13*02 F, or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F or Homsap IGHV3-16*01 ORF or Homsap IGHV3-16*02 ORF or Homsap IGHV3-19*01 P or Homsap IGHV3-35*01 ORF or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 87 90.48 19/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattcacatttagtaa +11061 JY8QFUQ01BAJIQ No results +11062 JY8QFUQ01ANRI3 unknown (see comment) Homsap IGHV3-23*05 F 90 49.28 102/207 nt 8 8 X 8.8.X [1.17.34.X] null - No rearrangement found ctctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaagggactggttcgaccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11063 JY8QFUQ01BPU64 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 944 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARHAQYYYDSSGYYYLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'GA' (2 nucleotides at position 70 to 71 in the user submitted sequence), (cause frameshift); tggagtacaggctttaccagctactggatcggctgggtgcgccagatgcccgggaaaaggcctgantggGAtgggggatcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgagacacgcgcagtattactatgatagtagtggttattactacttagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11064 JY8QFUQ01BC33J productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame + ctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11065 JY8QFUQ01AN5X2 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 930 92.99 199/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 7 12 8.7.12 [1.16.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 85 in the user submitted sequence), (cause frameshift) tctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaagggctggtgtgggtgtcacgtagtaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcncatgcctggtccagggcttcttccc +11066 JY8QFUQ01CFWDU productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + ttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11067 JY8QFUQ01A62Y2 productive (see comment) Homsap IGHV1-18*01 F 858 89.25 191/214 nt 88.79 190/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-10*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARVIRTNWLDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'GC' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift); tggttacacctttactacctatggGCgtcaccctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggtaatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacagccgtatattattgtgcgcgagtgattcggaccaactggctcgacccctggggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11068 JY8QFUQ01B0MEN productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcc +11069 JY8QFUQ01DLF2L productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 871 90.14 192/213 nt 89.67 191/213 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.16.38.11] CAREFRAPSLARYGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11070 JY8QFUQ01BXKLZ No results +11071 JY8QFUQ01CDA18 productive Homsap IGHV4-61*02 F 830 86.43 191/221 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-21*01 F 2 10 7 19 10.7.19 [1.17.38.11] CAREAPKTAGDSYGSLAMDVW in-frame + tctctggtggctccgtcagtagtggttcttactactggagctggacccggcagcccgccgggaagggactggagtggattgggcgtgtccacagcggtggcagttccgactacaacccgtccctcacgggtcgagccaccatcttagtggactcctccaagaatcagttctccctgaggctgacctctgtgacggccgcagacgcggccgagtatttctgtgcgagagaggcgcccaagacagcaggtgattcctacggctctctcgctatggacgtctggggccaagggaccacggtcatcgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggcttcttcccccc +11072 JY8QFUQ01BDJ01 productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [1.17.38.11] CSNGYGDFPRRW in-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gtctggattcaccttcaggagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgacaaattctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +11073 JY8QFUQ01A1RU8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 928 93.81 197/210 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-21*01 F 3 7 8 16 7.8.16 [X.17.38.11] CARGRIVSVGMSGWFDPW in-frame - ttcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtttattactgtgcgagaggccgaatagtgtcggttggtatgtcaggctggttcgacccctggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11074 JY8QFUQ01A9A38 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 929 91.4 202/221 nt 90.95 201/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 14 10.7.14 [1.17.38.11] CARRALDSSGHYIDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 121 to 121 in the user submitted sequence), (cause frameshift); tctctggtggctccatgagcagtggtaattactgctggggctggggccgccagcccccaggaaaggggctggagtggattggaagtatgtgttatggtgggagcacctactacagcttgtCcccccaagggtcgagtcaccatatccatagactcgtcgaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagacgcgcattagacagtagtggtcattacattgacatctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggttcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +11075 JY8QFUQ01AZ4IH productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARDRRPLREFDCW in-frame - ctctggattcaccctctccagctatgctatgcactgggtccgccagtctcccggcaaggggctagagtgggtggcagctatttcatatgatggaagtaaaatatattacgcagactccgtgaggggccgcttctccatctccagagacagttccaagaacactctgcatttgcaaatggacagcctgagacctgaggacacggctacatattactgtgcgagagatagacggccacttagggagtttgactgttggggccagggaaccccggtcgccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11076 JY8QFUQ01AX6UQ No results +11077 JY8QFUQ01CSMNR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 931 92.59 200/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11078 JY8QFUQ01BHGDW productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - ctctggattccccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaggggccgattcaccatctccagagacaacgccaggaactcattgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11079 JY8QFUQ01DOLHE No results +11080 JY8QFUQ01A7QNQ productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11081 JY8QFUQ01BA7U2 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 752 83.03 181/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctgggttcacattcagtaactactggatccactgggtccgccaagctccaggaaaggggctagagtgggtcgcacgtattaatgatgctggaaagcgtgccgacttcgcgactttcgtgaagggccgattctccatctcccgagacaacgccaagaacacagtgtatctggaaatgactagtctgagagtcgacgacacggctgtctatttttgtgcaatgcgattttgtggtggtcctgagtgctacccttatcttgacaactgggggccagggaaccccgtgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11082 JY8QFUQ01C4MXA unknown (see comment) Homsap IGHV4-30-2*01 F, or Homsap IGHV4-30-2*02 F or Homsap IGHV4-30-2*03 F or Homsap IGHV4-30-2*05 F or Homsap IGHV4-30-2*06 F 103 70.45 31/44 nt 68.18 30/44 nt X X X X.X.X [14.X.X.X] null + No rearrangement found stop codons in FR1-IMGT, from codon 7 of V-REGION: 6 nucleotides (from position 128 in the user submitted sequence), (do not cause frameshift) tggggaagaagccctggaccaggcatgcgacgaccacgttcccatcttgggggtgctgtcgaggctcagcgggaagaccttggggctggtcggggatgctgggggctggcggatgcagttccaggagtaaccactgaaggacccaccacagac +11083 JY8QFUQ01A1Y2H productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 921 92.52 198/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 8 8 11 8.8.11 [0.17.38.11] CAKVGNLYFFEYW in-frame - tggattcagcttcagtagctacagtatgaactgggtccgccaggctccagggaaggggctggagtggatttcatctattagcaccaccagtagtaccataggctacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagacgaggacacggctgtgtactactgtgccaaagtgggtaacctgtatttctttgaatactggggccggggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11084 JY8QFUQ01ACOQH unproductive Homsap IGHV4-61*02 F 978 94.09 207/220 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD1-1*01 F 1 10 7 X 10.7.X [1.17.38.11] CARVRARSNSHPGHSWFD#PW out-of-frame + ctctggtggctccatcagcagcagtagttactactcgacctggctccggcagcccgccggaaagggaccggagtggattgggcatatctatagtagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcggacacggccgtgtattactgtgcgagagtgagggcgcgcagtaatagtcaccccggccacagctggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaaccggtgacggtgtcgtggaactca +11085 JY8QFUQ01ADHG3 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11086 JY8QFUQ01CP5Y2 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [2.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) agcctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11087 JY8QFUQ01DLJGF productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*03 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD5-12*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDQRDYDYIYYYGMDLW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 67 of V-REGION: 'T' (1 nucleotides at position 108 to 108 in the user submitted sequence), (cause frameshift); ctctggattctccctcaggaatcatgctatgcactgggtccgccagactccaggcaagggactcgagtgggtggcagttatctcatttaatggacgaaggaagtactTatgcagacttcgtgaagggccgattcaccatcaccagggacaattcccagaacactctgtctctgcaattgaatagcctgggaactgaggacacggctgtctattactgtgcgagagatcagcgtgactacgattacatctactattacgggatggacctctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11088 JY8QFUQ01CF3EH No results +11089 JY8QFUQ01A8IOY productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11090 JY8QFUQ01B8XC4 No results +11091 JY8QFUQ01DQ77V productive Homsap IGHV3-11*01 F 987 94.55 208/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - agcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +11092 JY8QFUQ01C4GBD No results +11093 JY8QFUQ01AGWHU productive (see comment) Homsap IGHV3-48*01 F 1095 100.0 220/220 nt 99.55 219/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.17.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtagctatagcatgaactgggtccGgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11094 JY8QFUQ01BRTEE productive (see comment) Homsap IGHV3-7*01 F 891 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgagGaaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggatacttccccgaaccggtgacggtgtcgtggaactcagg +11095 JY8QFUQ01BZKWG No results +11096 JY8QFUQ01B59AU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcanttccccgaaccggtgacggtgtgcgtggaactca +11097 JY8QFUQ01B5XZZ productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 904 91.2 197/216 nt 90.28 195/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [1.17.37.11] CAKVSGNSRTYWYLDIW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 86 of V-REGION: 1 nucleotides (from position 163 in the user submitted sequence), (cause frameshift) ttctggatacaactttcccagatattggatcgcctgggtgcgccagattcccgggagaggcctggagtgggtggggatgatctatcctggtgactctGgagaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacgcgtccatgaacacgcctacctgcagtggagcagcctgaaggcctccgacaccgccatatacttctgtgcgaaggtctctggtaactctcgaacctactggtacctcgatatctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11098 JY8QFUQ01CI8E6 productive Homsap IGHV1-18*01 F 885 90.65 194/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-10*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARVIRTNWLDPW in-frame + tggttacacctttactacctatggcgtcacctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggtaatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacagccgtatattattgtgcgcgagtgattcggaccaactggctcgacccctggggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +11099 JY8QFUQ01BKBYB productive (see comment) Homsap IGHV4-39*03 F 918 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 6 17 10.6.17 [0.17.38.11] CARSITLTVVVMNDAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) ccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11100 JY8QFUQ01AXJHF unproductive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-8*02 F 1 8 8 X 8.8.X [0.17.38.11] CARDGYLPGNG#DFW out-of-frame + tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacgggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11101 JY8QFUQ01CX33A productive Homsap IGHV3-7*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatcttcagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctcag +11102 JY8QFUQ01BNGRJ productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CASAPSDSSGYYFSYW in-frame + tggatacaccttcaccagttactatatgcactgggtccgacaggcccctggacaagggcttgagtggatgggaatgatcaaccctagtggcggaagcacaatctacgcacagaacttccagggcagagttgccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgctagcgccccctctgatagtagtggatactacttttcctactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11103 JY8QFUQ01AXNJJ No results +11104 JY8QFUQ01DET16 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11105 JY8QFUQ01BGTBC No results +11106 JY8QFUQ01BHSYH productive Homsap IGHV3-7*01 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + gctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11107 JY8QFUQ01AVDQK productive Homsap IGHV3-7*03 F 967 94.44 204/216 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKEIAVSGEGRGLL in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggccgtatattattgtgcgaaagagatagcagtgagtggtgaggggcgtggacttctgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11108 JY8QFUQ01B6JUY No results +11109 JY8QFUQ01ALDM8 No results +11110 JY8QFUQ01C6Z5P productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 953 93.95 202/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - tctctggtggctccatcgatagttactactggacctggatccggcagccccacgggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +11111 JY8QFUQ01CHP7M unproductive Homsap IGHV3-7*01 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.16.38.11] CATSPFTVTTGKDAY## out-of-frame + in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift) ctctagattcacctttaggacatattggatgagttggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggcccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +11112 JY8QFUQ01CKJ8C No results +11113 JY8QFUQ01BLUE2 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 147 52.11 111/213 nt 8 8 X 8.8.X [1.17.36.X] null - No rearrangement found ctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgaagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +11114 JY8QFUQ01CPVDU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1005 95.45 210/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - ggcctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11115 JY8QFUQ01CLAMG productive Homsap IGHV4-61*02 F 870 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.38.11] CARDFGGSYNLVAYW in-frame + ctctggtgactccattagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11116 JY8QFUQ01ALAXK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11117 JY8QFUQ01DKCDX productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11118 JY8QFUQ01CQK1A No results +11119 JY8QFUQ01CY9AT unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.37.11] CVSDLAGQKGF# out-of-frame + in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 169 in the user submitted sequence), (cause frameshift) cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11120 JY8QFUQ01DBHC6 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctgggtggctccatcagtagttactactggagctggatccggcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11121 JY8QFUQ01DD3NG productive (see comment) Homsap IGHV4-61*02 F 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARAWNGDYEVGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'A' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift); ctctgtgactccatcggtaatggaagttactactggagctAgggtccggcagtccgccgagaagggactggagtggattggacatatctataccagagggagcaccaactacaacccctccctcaagagtcgagtcaccatttcagccgacacgtccaagaatcagatctccctgaagttgacctctgtgaccgccgcagacacggccgtatattactgtgcgagggcgtggaacggtgactacgaggtgggctggttcgacccctggggccaggggaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11122 JY8QFUQ01BFUTU No results +11123 JY8QFUQ01DHFDA productive (see comment) Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 98.61 213/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccGttcagtagctatagcatgaactgggtccgGccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11124 JY8QFUQ01AKGE1 unproductive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1078 98.65 219/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 X 10.7.X [2.17.38.11] CARDRGP*QLVQNGI#DYW out-of-frame - stop codons gtctctggtggctccatcaacagtggtggttactactggagttggatccgccagcacccagggaagggcctggagtggattgggtacatctattacagtgggagtacctactacaacccgtccctcaagagtcgagttaccatatcagtagacacgtctaagaaccagttctccctgaagctgagctctgtgactgccgcggacacggccgtgtattactgtgcgagagatcgggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11125 JY8QFUQ01AIXTO unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 348 96.0 72/75 nt 8 X X 8.X.X [1.16.X.X] null - No rearrangement found tctggattcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctca +11126 JY8QFUQ01ATFWJ productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11127 JY8QFUQ01A9LDO productive (see comment) Homsap IGHV3-7*01 F 896 90.37 197/218 nt 89.45 195/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'TT' (2 nucleotides at position 15 to 16 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); cctctaaattcaccTTtttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaAagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11128 JY8QFUQ01CTV37 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11129 JY8QFUQ01CVMEU No results +11130 JY8QFUQ01BVR5D unknown (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found ctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggccctatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11131 JY8QFUQ01A37SY No results +11132 JY8QFUQ01B8KMJ unproductive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-9*01 F 1 10 7 X 10.7.X [1.17.38.11] CARCPNYNIGTRG#FDYW out-of-frame + tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccggggggctttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11133 JY8QFUQ01ARU4K productive (see comment) Homsap IGHV4-4*07 F 1052 99.07 213/215 nt 97.21 209/215 nt Homsap IGHJ1*01 F (see comment) 197 86.54 45/52 nt Homsap IGHD6-13*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARTAAAGQFDPW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctgggtgctccatcaGgtagttactacCtggagctgGgatccggcagcccgGccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgaggaccgcagcagctggacagttcgacccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11134 JY8QFUQ01BX232 No results +11135 JY8QFUQ01AVH6A productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1057 99.07 214/216 nt 98.15 212/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [2.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttcctaCctggagctGggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11136 JY8QFUQ01C3JR0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11137 JY8QFUQ01B5B8P unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 810 85.71 186/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11138 JY8QFUQ01CD1M7 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +11139 JY8QFUQ01AUTBM unknown (see comment) Homsap IGHV3-21*04 F (see comment) 720 81.11 176/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (81,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11140 JY8QFUQ01AXF50 unproductive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 1 9 7 X 9.7.X [1.17.38.11] CARDQRADLAPRQ#FDYW out-of-frame - tctctggtgactccatcagcaatgatagttggtggagttgggtccgccagcccccagggaaggggctggagtggattggggaaatctatcatactgggagcaccaactacaacccgtccctcaagagtcgagtcaccatatcactcgacaagtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacgcggccgtctattactgtgcgagagatcagcgggccgatttggcacctcgtcaacctttgactactggggccagggagcccaggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11141 JY8QFUQ01BC5YA productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11142 JY8QFUQ01DG2MU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11143 JY8QFUQ01CSS8X productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11144 JY8QFUQ01BKEKF No results +11145 JY8QFUQ01B5KVE unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 138 64.1 50/78 nt 8 X X 8.X.X [1.16.X.X] null - No rearrangement found ctctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +11146 JY8QFUQ01AI7P6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 743 82.57 180/218 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARTPCSGGNCYLRGHDLW in-frame + Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcgggtatttattattgtgcgcggacgccttgcagtggtggaaattgttaccttagaggccacgacctctggggccagggaacccaggtctccgtttccccagcagtccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccga +11147 JY8QFUQ01B2H3D productive Homsap IGHV4-61*02 F 897 90.0 198/220 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 14 10.7.14 [1.17.38.11] CARAKVVIRPNWFDPW in-frame - ctctggtgactccatcaccagtggtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaatccctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagagcaaaagtagtgatccgtcccaactggttcgacccctggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11148 JY8QFUQ01CIBG4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 901 90.41 198/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [2.17.38.11] CARWRGQQSEMEYW in-frame - gcctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +11149 JY8QFUQ01C5WRD No results +11150 JY8QFUQ01CMI8I productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11151 JY8QFUQ01BE69W productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcacgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11152 JY8QFUQ01BECQV No results +11153 JY8QFUQ01C4C7K unproductive Homsap IGHV3-11*01 F 824 86.7 189/218 nt 86.24 188/218 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD5-12*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDLYGADDL# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); cctctggattcccctttaaggactactccatgaactggatccgccaggctccagggaagggactggagtggAttttcatacatgagcagcactggtgagaccatatattacgcggactttgtgaagggccgattcaccatctccagggacaccgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccgagggcttcttcccccag +11154 JY8QFUQ01BPMR5 productive (see comment) Homsap IGHV3-48*02 F 878 89.45 195/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVTERGGGLLRYLDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); gctctggattcatgttcggtagttatagtctgaattgggtccgccaggctccaggGgaaggggctggagtggAttttcatatattagtagcagtagtcaaacgatttactacgcaaactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgcgagacgacgacacggccatttactactgtgtgacagagaggggcgggggcctattacgatatttggacttatggggcctgggaactcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11155 JY8QFUQ01CHCL3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD3-9*01 F 2 8 8 18 8.8.18 [1.17.38.11] CVKVAGDYRTPNYGWHFDLW in-frame - ctctggattcacctttagcacctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggtagtggtggcagcacattctactcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactggatctgcaaatgaatagcctgagaggcgaagacacggccgcatattactgtgtgaaagtggccggtgactatagaactcccaactacggctggcacttcgatctctggggccgaggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11156 JY8QFUQ01BTY4N No results +11157 JY8QFUQ01ACHVK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 978 94.09 207/220 nt 93.64 206/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); gcctcctggattcaGcattcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11158 JY8QFUQ01AMK5G productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-8*02 F 2 8 8 20 8.8.20 [1.17.38.11] CARDLWLCSGGECYHRGGFENW in-frame + ctctgggttcaccttcagtaactcctggatgcactgggtccgccaagctccagggaaggggccggagtgggtctcacgtattaatagtgatgggagtaatacaatctacgcggactccgtgaagggccgactcaccatctccagagacaacgccaaaaacacggtgtatctgcaattgaacagtctgagagccgaggacacggctgtgtactactgtgcaagagatctgtggctttgtagtggtggtgaatgctatcatcggggtggttttgagaactggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +11159 JY8QFUQ01AWGJ4 productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame + tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtttccccagcatccccgaccagccccaaaggtcttcccgctgagccctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +11160 JY8QFUQ01DFHN2 productive (see comment) Homsap IGHV1-8*01 F 939 93.46 200/214 nt 91.59 196/214 nt Homsap IGHJ3*01 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-16*01 F 1 8 8 14 8.8.14 [0.17.38.11] CARWRLGSGLEGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagttatgatatcaattgggtgcgacaggGccactggacaaGgggcttgagtggatgggatggatgagGcccaaacagtactGataaggggctatgcacagaagttccagggcagagtcaccatgaccaggagcacctccataagcacagcctacatggagctgagtagcctgacatctgaagacacggccgtctattactgtgcgagatggcgattgggttcggggcttgagggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11161 JY8QFUQ01A7OD5 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccgaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11162 JY8QFUQ01DFOB1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKGIVGASMQADWFHPW in-frame - cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggagggggctggagtgggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11163 JY8QFUQ01DOMNJ productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 7 22 8.7.22 [1.17.38.11] CARVKTDYYDSSGSYLPLYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggtgactccttcagaactcactactggagttggattcgacagcccccgggggaggAgattggaatggattggcaatatatattatattgggaccaccaactacaacccctccctcaagagtcgagtcaccatgttagtggacacgtccaagaagcagttctccctgagactgagttctgtgaccgctgcggacacggccatgtattattgtgcgagggtcaagactgattattatgatagtagtggttcttacctgcccctgtatttctttgattactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11164 JY8QFUQ01AG0SV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggactcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11165 JY8QFUQ01BCOXR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11166 JY8QFUQ01DVSTX unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARKRVPGGNFLM#DYW out-of-frame + cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggaactttttgatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc +11167 JY8QFUQ01CPSV4 unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11168 JY8QFUQ01BG5T6 productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGYW in-frame - ctctggattcagctttagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaaatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtttttgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgattagtagtgatttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11169 JY8QFUQ01B6KYS unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDNYGDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11170 JY8QFUQ01ANZL9 No results +11171 JY8QFUQ01A4T3U productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [2.16.38.11] CARDPVGISGSVNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaagggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacgactgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11172 JY8QFUQ01BL4XI productive Homsap IGHV3-33*03 F 855 88.48 192/217 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARADGAGYNYATYYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gtctggattcaacttcaatagtcatgccatacactgggtccggcaggctccaggcaaggggctggagtgggtggcaggtgtttggtatgatggaagtgacaaatactatgcagactcagtggcgggccgattcaccatctcccgagacaactccagaaaaacagtgtttctggaaatgaacagtctgagaggcgaggacacggctgtgtattactgtgcgagagcggatggtgctggttacaactacgcgacgtactactttgattcctggggccagggaacccaggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +11173 JY8QFUQ01DECT5 productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 190 89.36 42/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtccgtggaactcag +11174 JY8QFUQ01A9S30 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt 89.14 197/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 65 to 65 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaAggggctggagtggaTttgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11175 JY8QFUQ01C95PS No results +11176 JY8QFUQ01BH4FT productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 708 81.99 173/211 nt 81.04 171/211 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [0.16.38.11] CARLDGHFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,99% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 76 of V-REGION: 'C' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 75 in the user submitted sequence), (cause frameshift) ctgggttcaccatcactcactactccatggcctgggtccgccaggctccggggaaggggctggagtgggtctcattaattatcccggcgggagcacattccacgcagactccgtgagggggcgcCgtcatcatctccagagacgaatccaagagtgagctgtatcttcggatgacgaaagtgaaagccgaagacgcggccgtatattactgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +11177 JY8QFUQ01CATEA productive Homsap IGHV4-39*03 F 924 91.32 200/219 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + ctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11178 JY8QFUQ01CZTAK unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*03 F or Homsap IGHV4-34*06 F 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CASWNTLAYYFGF#W out-of-frame + in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcaggggttatcactggagctggatccgccagtccccagggaaggggctagagtgggttgggAgaaatcgattttggtggaaccaccaagtacaagtcgtccctcaagagtcgagtcaccatatcactagacacggccaagaaccacttctcgttgaacctgcgctctgtgaccgccgcggactcgggagtgtattactgtgcgagttggaatactctggcttactactttggattcttggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtnaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +11179 JY8QFUQ01CVJA3 productive (see comment) Homsap IGHV3-7*01 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.16.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 78 in the user submitted sequence), (cause frameshift) ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11180 JY8QFUQ01CQG0I unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 885 88.79 198/223 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 10 X 8.10.X [1.17.38.11] CTTRPRGGNHLA#DYW out-of-frame + ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggttggccttattaagaccaaacctgatggttggacaacaatctactctgcacccgtgaaaggcagattcatcatttcaagagatgattcaaaaaacatggtgtttctgcaaatgaacaacctgagaaccgaggacacagccctttattactgtaccacacggccccggggtgggaaccacttggccttgactactggggcctgggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11181 JY8QFUQ01BTFVE productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 923 91.74 200/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 9 7 12 9.7.12 [1.17.38.11] CAANLGHGSYFKYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 121 to 121 in the user submitted sequence), (cause frameshift); tctctggtggcGtccatcagcagtagtaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggacaaatccatcatggtGgggggcaccaattacaacccgtcCcctcgagagtcgagtcactatatcagtagacaagtccaagaaccaattctctctgagaatgacctcttttaccgccgcagaaacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11182 JY8QFUQ01DA2KM productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt 93.78 211/225 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGNYYDSGGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctagcagcagtgttgTtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcgaataactatcaagccagacgcatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtatattactgtgcaagagggggtaattactatgatagtggtggtcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +11183 JY8QFUQ01AWOU0 productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); gctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggGactctgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11184 JY8QFUQ01CRKTD productive (see comment) Homsap IGHV3-7*01 F 938 91.86 203/221 nt 90.95 201/221 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDSPSAYDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); cagcctctggattcaGcctttagtttatCactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11185 JY8QFUQ01C50GB No results +11186 JY8QFUQ01BKGXH unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKYVEGWS*YGGLL##SYAMDVW out-of-frame + stop codons ttctggattcgcctttagccgttatgccatgacttgggtccgccagactccagggagggggctggagtgggtctcaggtctcagtggtagtggtgatagcacatactactcaaactccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggaggggtggtcatgatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagccctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11187 JY8QFUQ01BN3SN productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 912 90.13 201/223 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARHSRLVRYFEFW in-frame - tgtctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11188 JY8QFUQ01CJXQH productive Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARPAGEGDPFFHYYSGLDVW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11189 JY8QFUQ01ACVQ4 productive Homsap IGHV4-4*07 F (see comment) 683 80.0 172/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-9*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARESTNSIGDPRHLDSW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01ACVQ4 ; 8 AA in Homsap_IGHV4-4*07), and low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggccccatcaacacacatgacttctattggacgtggatccggcagtccgccgggaggggactggagtggctcggacgtgtctatatgaatggcattagtgaccacaatccagtcttcactagtcgtctcaccatgtccattgacacgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcggactcggccctatattactgtgcgagagaaagtactaattcgattggcgacccgagacaccttgactcttggggccagggaaggttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +11190 JY8QFUQ01APAUY unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 186 97.44 38/39 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found cctctggattcatcttcagtagctactggatgcactggg +11191 JY8QFUQ01B6PJY unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 724 81.48 176/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (81,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11192 JY8QFUQ01C0LHV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-16*02 F 1 8 8 16 8.8.16 [1.17.38.11] CAKDPQQLLEDINWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 86 of V-REGION: 'A' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); ctctggattcacctttcgcagctatgccatgagctgggtccgccaggctccaggaagggggctagagtgggtctcatctatcagtggtagtggtgataaaacaaagtacgcagactccgtgaagggccggttcaccatctccagagacaacgccaggaacacAtttttatctgcaaatggacagcctcagagccgaggacacggccgtctattactgtgcgaaagatcctcagcagttattggaagacataaactggttcgacccctggggccagggcacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11193 JY8QFUQ01DFINT productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*16 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDLPGWTGYFDHW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'A' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); ctctggtttcatcttcagtgtctatAcccatgcactgggtccgccaggcgccaggcaaggggctagagtgggtggcacttatatcatataatggaggtaatacatactacgcagactccgtgaagggccgattcaccatctccagagacaactccaacaacacgctgtatctgcaaatgaatgggctgagaactgaggacacggctgtttattactgtgcgagagatctgccaggctggacaggctactttgaccactggggccagggagccctgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11194 JY8QFUQ01AIZWZ productive Homsap IGHV3-48*01 F 1075 100.0 216/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11195 JY8QFUQ01B6T6U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11196 JY8QFUQ01B6SGU productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*03 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 7 16 8.7.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 2 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtacctattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcatatgatggaaaaaaagtattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtacctgcaaatggacagcctgaggcctgaagacacggctgtatattactgtgccagagatgagctcccttgggatacaatagagtactactttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +11197 JY8QFUQ01BNP6J productive Homsap IGHV3-7*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-2*01 F 2 8 8 9 8.8.9 [1.17.38.11] CATRSRSPANW in-frame - cctctggattcacctttagaagctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtggccaccataaacgaggatggaagtgacagaacctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaaaaattcattgtatctacaaatgaatagcctgagaaccgacgacacggctcgatattactgtgcgacgcgtagtagaagtccggcgaactggggccagggaagcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11198 JY8QFUQ01B9XU2 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 974 93.67 207/221 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD5-18*01 F 3 10 7 14 10.7.14 [1.17.38.11] CARSQSRYSWGDFLHW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtgactccatcagcagtactagttactactggggctggatccgccagcccccagggagggggctggagtggattggaagcatctattatagtgggagcacctcctacaacccgtccctcaagagtcgaatcaccatgtccatagacatgtccaagaaccaattctccctgaggctgagctctgtgaccgccgcagacacggctgtttatttctgtgcgcggtcccagagtagatacagttggggtgacttcttacactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +11199 JY8QFUQ01C3PST productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 15 8.8.15 [2.17.37.11] CVRGGVSGAFRWGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 107 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgacgacacggctgtttactactgtgtgagagggggagtcagtggggccttcaggtgggggtttgactactggggccagggaaccctggccaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11200 JY8QFUQ01DPHN5 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F (see comment) 204 78.79 52/66 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found Low V-REGION identity (78,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagtttcagtacctatgcaatgcactgggtccgccaggctccagggcttcttccccc +11201 JY8QFUQ01CGUTY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'GG' (2 nucleotides at position 125 to 126 in the user submitted sequence), (cause frameshift); ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaagGGggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtggggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +11202 JY8QFUQ01BQNV9 No results +11203 JY8QFUQ01AUUSZ productive Homsap IGHV3-48*03 F 865 88.58 194/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDKGWSGYGMDVW in-frame - gcctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11204 JY8QFUQ01CJ7YK productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +11205 JY8QFUQ01A02KS productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARGGQRTGWYEYW in-frame + ctctggattcacctttagtacctattggatgacttgggtccgccaggctccagggaaggggctggagtgggtggccagcataaaaaatgatggaagtgagaaatcctatgtggactctgtaaagggccgattcaccatctccagagacaacgccgagaactcactgtatttgcaagtgaacaacctgagagccgaggacacggctgtatattactgtgcgagagggggccaaagaactggctggtacgaatattggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc +11206 JY8QFUQ01DRIF5 unproductive Homsap IGHV3-9*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKMILVSGWSDL#LDYW out-of-frame + ctctggattcaagtttgatgattatgccgcgcactgggtccggcaagctccagggaagggcctggaatgggtctcaggtattagttggaatggtggtagcacacgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaacgccctgtatctggaaatgaacattctgagaactgacgacacggccttatattactgtgcaaaaatgattttggtcagtggctggtcggacctttttggactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11207 JY8QFUQ01COP99 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + tctggatacatgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11208 JY8QFUQ01BUR31 No results +11209 JY8QFUQ01A3VOS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag +11210 JY8QFUQ01CIYMG No results +11211 JY8QFUQ01CZGL0 No results +11212 JY8QFUQ01CJ3GU productive Homsap IGHV3-7*01 F 1027 96.8 212/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 12 8.8.12 [2.17.38.11] CTKVVGGYDTADYW in-frame - gcctctggattcacctttagtagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaacgaagatggaagagcgcaaaactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggatacggctgtgtattactgtacgaaagtcgtcggtggctacgatactgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11213 JY8QFUQ01DCW32 unproductive Homsap IGHV3-48*02 F 923 91.74 200/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*02 F 1 8 8 X 8.8.X [1.17.38.11] CARDAHFGRYY#FDLW out-of-frame - in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'ACT' (3 nucleotides at position 88 to 90 in the user submitted sequence), (do not cause frameshift); cctctggattcacctttagcacctatagcatgcactgggtccgtcaggctccagGggaaggggctcgaatggattgcatacattagtACTagtactactagtcccatgtactacgcagactctgtgaagggccgattcaccatctccagagacaatgccgataactcactgtatctgcaaatgaacagcctgagagacgacgacacggctgtttattattgtgcgagagacgcccattttgggagatattattttttgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11214 JY8QFUQ01BT4R4 productive (see comment) Homsap IGHV3-7*01 F (see comment) 747 82.95 180/217 nt 82.03 178/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 97 in the user submitted sequence), (cause frameshift) cctctggattcgtctttactaatcattggatgagttggGgtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11215 JY8QFUQ01DWZTC No results +11216 JY8QFUQ01ACVZU productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 912 92.06 197/214 nt 91.12 195/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 7 8 10 7.8.10 [1.17.37.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 103 in the user submitted sequence), (cause frameshift) tctggattcagcttaagttctatggcatgaactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11217 JY8QFUQ01CXYEY unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 243 57.14 124/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (57,14% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatatactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11218 JY8QFUQ01DQ427 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1001 95.02 210/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 2 10 7 12 10.7.12 [1.17.38.11] CVRHRRLELLPDYW in-frame - tctctggtgactccatcagcagtaatagtttctactggggctggatccgccagcccccagggaaggggctggagtggattgggaatatctattatagtgggagcacctactacaacccgtccctcgagagccgagtcaccatatccgtagatacatccaggaaccagttctccctgaagctgaggtttgtgaccgccgcagacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11219 JY8QFUQ01A720R productive Homsap IGHV3-43*01 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-8*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDRIGSLYYFDHW in-frame + cctcaggattcacatttgctgaatataccatgcactgggtccgtcaagttccggggaagggtccggagtgggtctctcttattagttgggatggtggcagcacatactatgcagactctgtgaagggccgattcaccatctccagagacaacagcaaggactccctgtatctgcaaatgaacagtctgagaactgaggacaccgccttgtattactgtgcaaaagataggattgggtccttgtactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +11220 JY8QFUQ01CPBZM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +11221 JY8QFUQ01CD1Z2 No results +11222 JY8QFUQ01BAN07 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 160 80.0 40/50 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDRLNW*LHIRR#FDLW out-of-frame + stop codons Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) cctctaaatttgacttcagtgactatggcatgaactgggtccgccaggttccagggaaggggctggagtgggtctcctacataagtcgtctgagtcgccaaatatatgtcgctgacccagtgaagggccgattcaacatctccagagacaacgccaagaattcactgtatctgcaaatgaacaacttgcgggtcgaagacacggctgtgtatttttgtgccaaagatcgcctgaactggtgactacacattcggcgcattttgatctgtggggcccagggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggaccanttgcccccgaaccggtgacggtgtcgtggaactc +11223 JY8QFUQ01CDHH3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 870 88.64 195/220 nt 88.18 194/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); agcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtGgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11224 JY8QFUQ01BT4AX productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +11225 JY8QFUQ01BR5IZ No results +11226 JY8QFUQ01C7WRQ unproductive (see comment) Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD3-16*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARVIPGRGNYAF*CLG in-frame + stop codons ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgctttttgatgtctgggggccggagggacaatggtcaccgtctcttcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11227 JY8QFUQ01DC7DQ productive Homsap IGHV3-21*04 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11228 JY8QFUQ01CIEOW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - ctctgacttcacctttgatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcag +11229 JY8QFUQ01AH4O3 unproductive Homsap IGHV4-61*02 F 934 91.44 203/222 nt 89.64 199/222 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [2.17.38.11] CARATLSDVDTPMGFDS## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'CT' (2 nucleotides at position 90 to 91 in the user submitted sequence), (cause frameshift); gtgtctggtgactccatcagcagtggGtacttactactGggaactggatacggcagcccgccgggaagGgggctggagtggattgggcgCTtttttataccagtgggagcaccaagtacagcccctccctcaagagtcgagtcaccatatcaggagacacgtccaagaaccaggtctccctgaggctcagtcatgtgaccgccgcagacacggccgtctatttctgtgcgcgagcaacgctgtctgacgtggatacacctatgggttttgactcctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccagg +11230 JY8QFUQ01CE3GK unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 897 90.0 198/220 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) agcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11231 JY8QFUQ01ANN3Q No results +11232 JY8QFUQ01CBXI5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 895 90.74 196/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + tccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11233 JY8QFUQ01A3QP3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCGNGACHVADYW in-frame - cctctggattcgcctttaggagtgagtggatgaactgggtccgccaagccccagggaaggggctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccatgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11234 JY8QFUQ01AMZ6W productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARVDFYGSSKYKGFDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); tctctggtaactccatcacagattattactggagctggctccggcagtctccagggaagggactggagtggattggaaatgtcCttttacagtgggagagccaactacaacccctccctcaagagtcgagtcaccatatcagtagccacgtccaggaaccagttctccctgaagctcaggtctgtgaccactgcggacacggccatatattattgtgcgagagttgatttctatggttcgagtaaatataaggggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11235 JY8QFUQ01BOIEU productive (see comment) Homsap IGHV3-7*01 F 1022 96.79 211/218 nt 96.33 210/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGcctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11236 JY8QFUQ01AGGTS productive Homsap IGHV3-64*02 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-9*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVRGRPMAGFHGILYDNW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttagtatcagtaattatggtattcactgggtccgccaggctccagggaggggactggaacttgtttcagctattaccaacaatgcgcatagtgtagtctatgtagactctgtgaagggcagattcatcatctccagagactattccaagaacacgttgtatcttcaaatgggcagactgagaccagaagacacggctgtgtactactgtgtcagagggcggcctatggctggctttcatggaatcctttatgacaactggggcctgggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggg +11237 JY8QFUQ01C624X unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 984 93.72 209/223 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-15*01 F 3 8 10 X 8.10.X [1.17.38.11] CAADGCPGGTCYHG#LDMW out-of-frame + ctctggattcactttcagtaacgtctggatgcactgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgctggtggggcaacagaatacgctgcgcccgtgagaggcatattctccatctcaagagatgattcaaagaacacgttgtatctgcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtgccgcagatggttgtcctggtggtacctgctatcatggttttggatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagcccctaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcncatgcctggtccagggcttcttccc +11238 JY8QFUQ01ANT01 productive (see comment) Homsap IGHV3-33*03 F 904 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.37.11] CARAASHGWYLDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 190 in the user submitted sequence), (cause frameshift) gtctggattcatcttcagtggctatggcatgcactgggtccgccaggtcccaggcaagggcctggagtgggtggcggttattcggtatgatggaactaatgatgactatgcagactccgtgaagggccgattcaccatctccaaagacacctccaagaacactctctatctgcaaatgaacagcctgaggccgaggacacggctatatattattgtgcgagagcggctagccatgggtggtacctggactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11239 JY8QFUQ01BIEF4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.13 199/216 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGYHGPFDS## out-of-frame + tctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacacatactactcagactccgtgaggggccggttcaccatctccagagacaacgccaagaacacgatgtatctgcaaatgaacaccctgagagacgaggacacggccgtctatttctgcgcgaaaggttaccacggcccctttgactcttggggccggggcaaccctggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +11240 JY8QFUQ01A78FD unproductive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*03 F (see comment) 87 64.58 31/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDQVTEDY# out-of-frame + Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaacctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccctggtaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +11241 JY8QFUQ01AI87L productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 926 90.62 203/224 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD3-22*01 F 3 8 10 23 8.10.23 [1.17.38.11] CATDRPYYKKSLLADSGITTVWTFW in-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaaatcgctgctggccgactctggtattactacggtatggacgttttggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11242 JY8QFUQ01AK1LD unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CSKTPLGE#DYW out-of-frame - ctctggattcacctttagcaactatgccatgaactgggtccgccaggttccagggaaggggctggagtgggtctcacgtattaatgaagatgggaggactacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacaccaagaacacactgtatctgcagatggacagtctgagagccgaggacacggctgtgtattactgttcaaagacacctttgggggagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11243 JY8QFUQ01COFPE unproductive Homsap IGHV3-30*07 F, or Homsap IGHV3-30*16 F 923 91.74 200/218 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDSVPRASEAAYYFDS## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtatttattctatgcattgggtccgccaggccccaggcaaggggctagagtgggtggcagttatatcacatgatggaactaataaatattactcagactccgtgaagggccgattcaccatctccagagacaattccaagagcgcgctgtatctgcagctgaacgtcctgagcgccgaggacacggctgtctatttctgtgcgagagattccgtacctcgggcgtcagaggctgcctactactttgactcttgggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +11244 JY8QFUQ01AJ6ES productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11245 JY8QFUQ01CVDU4 productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggGggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11246 JY8QFUQ01CUMN3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.37.11] CVREGAATGSFYYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccaggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11247 JY8QFUQ01B3XHO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 940 93.06 201/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + tccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +11248 JY8QFUQ01CEW9N unproductive Homsap IGHV3-64*02 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSSPYFYDSNGY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaaggGgactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +11249 JY8QFUQ01C6YH3 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 840 88.32 189/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [1.17.38.11] CTRGRSDAWELSDHW in-frame + cgacgatgggtcctgcagaaactgcttctggagttggatccgccagtccccagggaaggggctggagtggattggggaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagtcgagtcaccatatcattagacacgtccaacaaccaagtctccctgaggttgagctctgtgaccgccgcggacacggctgtgtattactgtacgcgagggcgatccgacgcgtgggaattatcggaccactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +11250 JY8QFUQ01BFGVN No results +11251 JY8QFUQ01BM4NU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11252 JY8QFUQ01DXH62 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 152 57.14 76/133 nt 8 7 X 8.7.X [1.17.10.X] null + No rearrangement found stop codons cctctggattcaccttcagtagcctttggatgagctgggtccgccaggccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccc +11253 JY8QFUQ01CUEJA No results +11254 JY8QFUQ01BRKQG No results +11255 JY8QFUQ01BKUUH productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +11256 JY8QFUQ01DCJM7 No results +11257 JY8QFUQ01B8YA9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11258 JY8QFUQ01B56I8 productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc +11259 JY8QFUQ01AWAE8 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [2.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) tgttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11260 JY8QFUQ01DLE5Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11261 JY8QFUQ01CBHMF productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttc +11262 JY8QFUQ01AS1DF No results +11263 JY8QFUQ01DVZXG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1067 99.08 216/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-22*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARDSVTMIVVEYYFDYW in-frame + cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattcggtcactatgatagtagtggaatactactttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggagcacagcggccctggggctgcctggctcaaggcactacttccccggaaccggtgacggtgtcgtggaactca +11264 JY8QFUQ01CTRR8 productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11265 JY8QFUQ01B9TMB productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11266 JY8QFUQ01CPWPG productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 828 87.1 189/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGFSAWGQDAFDIW in-frame + ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11267 JY8QFUQ01DM0K4 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +11268 JY8QFUQ01B1WRM unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 748 82.65 181/219 nt 82.19 180/219 nt Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-3*02 F 1 8 8 X 8.8.X [2.17.38.11] CARIWDSWSGAF*CV# out-of-frame - stop codons Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagctttttgatgtgtgggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11269 JY8QFUQ01BWXHB unproductive Homsap IGHV4-39*07 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt 9 7 X 9.7.X [1.17.38.11] CARAVLDNAWPIYYDFLG (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (9 AA in JY8QFUQ01BWXHB ; 10 AA in Homsap_IGHV4-39*07), and low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctggtggctccatcaccacttggcattactggggctggatccgccagcccccaggggagggtctggaatggattggaaatgtctatcataatggcaatatcgcctatagcccgtcgcagaggagtcgaatcaccatatcagtagacacgtccaggaaccagttctccctgaagatgacctctgtgaccgccgcggacacggctgtctattactgtgcgagggctgttcttgacaatgcctggcctatatattatgactttttgggggcccaaggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccttggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11270 JY8QFUQ01B8WV1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11271 JY8QFUQ01CIBLS productive Homsap IGHV4-59*10 F, or Homsap IGHV4-61*02 F (see comment) 551 71.3 164/230 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [6.17.38.11] CARERDKSGGGAGDFDSW in-frame - Low V-REGION identity (71,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccagtggcattgttaatggcgaaggttttggtcgtttctactggaactgggtccggcagatcgacgggcaggggctagagtggatcgggcgtgtttatcgtgatgggatcacaaactacaatccctccttcgggacccgaataagtttgtcgttagactcgtccaagaggcagttttccctggagttacagtctgtgaccgccgcagacacggccttatatttttgtgcgagggagcgtgacaagtcgggcggcggggcgggcgactttgactcctggggccagggactcctggtcaccgtctcatctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11272 JY8QFUQ01A2R81 No results +11273 JY8QFUQ01AKJNV unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 832 87.5 189/216 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [2.17.38.11] CAREKGSGPPH#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) gcctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11274 JY8QFUQ01CZWU7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11275 JY8QFUQ01BH03V productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 840 88.32 189/214 nt 87.85 188/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [1.17.38.11] CTRGRSDAWELSDHW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cgacgatgggtcctgcagaaAactgcttctggagttggatccgccagtccccagggaaggggctggagtggattggggaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagtcgagtcaccatatcattagacacgtccaacaaccaagtctccctgaggttgagctctgtgaccgccgcggacacggctgtgtattactgtacgcgagggcgatccgacgcgtgggaattatcggaccactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +11276 JY8QFUQ01AL1N5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagacccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca +11277 JY8QFUQ01BA1SC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11278 JY8QFUQ01AK5UN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 893 89.59 198/221 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [2.17.38.11] CARADDYGDYPEFW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) aggcctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11279 JY8QFUQ01B5XW8 productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F (see comment) 759 84.11 180/214 nt 83.64 179/214 nt Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDRGKIAAIALDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); tggatacaAattttatcgactattatatagaatgggtgcgacaggcccctggacaaagacctgagtggatgggaataatcagccctagaggaaggagcccaacttacgcacagaacttccagggcagagtcactatgaccggcgacacgtccacgagcacagtctacatggaattgagtgatttgagatctgacgacacggccgtgtattattgtgcgagagatcggggcaaaatagccgcaatcgccttggacgtctggggccaagggaccacggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11280 JY8QFUQ01A6KC0 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11281 JY8QFUQ01A91ZM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt 85.32 186/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [1.17.38.11] CVKDRDFLWGTYRLQLEHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); cctctggattcagatttagcagctatgccaGtgagctgggtccgccagactccagaaaaggggcttgaatgggtctcaggcatcaatgataacggtcgaagcataaactacgcgggctccgtgaagggccggttcaccatctccagagacaattccaagagcacgttgtatctgcagatggatagcctgagccccgaggactcgggcatatattattgtgtgaaagatcgtgatttcctttggggcacttatcgtcttcaacttgaacattggggccagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11282 JY8QFUQ01CDH4K No results +11283 JY8QFUQ01CJJXA productive (see comment) Homsap IGHV3-33*03 F 904 91.2 197/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.37.11] CARAASHGWYLDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 190 in the user submitted sequence), (cause frameshift) gtctggattcatcttcagtggctatggcatgcactgggtccgccaggtcccaggcaagggccCtggagtgggtggcggttattcggtatgatggaactaatgatgactatgcagactccgtgaagggccgattcaccatctccaaagacacctccaagaacactctctatctgcaaatgaacagcctgaggccgaggacacggctatatattattgtgcgagagcggctagccatgggtggtacctggactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11284 JY8QFUQ01CRC4Q productive Homsap IGHV3-21*04 F 975 95.33 204/214 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [0.17.38.11] CARAVSNQVDVW in-frame + tggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11285 JY8QFUQ01ALN5G productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11286 JY8QFUQ01AVB9Z No results +11287 JY8QFUQ01DHO9S productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11288 JY8QFUQ01BV4T8 productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactca +11289 JY8QFUQ01DQYS5 productive (see comment) Homsap IGHV3-11*01 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaaggaactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11290 JY8QFUQ01CA390 No results +11291 JY8QFUQ01CWX55 productive Homsap IGHV3-7*01 F 904 91.2 197/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + tctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11292 JY8QFUQ01BPSCI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKRLQAVADDAFDFW in-frame + cctctggattcatctttagtagctatgccatgggctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgaacagcctgagagccgaagacacggccatatattactgtgcgaaaaggttgcaagcagtggctgatgatgcttttgatttctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11293 JY8QFUQ01B9L2E unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11294 JY8QFUQ01CELAQ productive Homsap IGHV4-59*10 F, or Homsap IGHV4-61*02 F (see comment) 502 68.83 159/231 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [7.17.38.11] CARERDKSGGGAGDFDSW in-frame - Low V-REGION identity (68,83% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccagtggcattattaatagcgaaggattttggtcgtttctactggaactgggtccggcagatcgacgggcaggggctggagtggatcgggcgtgtttatcgtgatgggatcacaaactacaatccctccttcgggacccgaataagtttgtcgttagactcgtccaagaggcagttttccctgaagttacagtctgtgaccgccgcagacacggccgtatatttttgtgcgagggagcgtgacaagtcgggcggcggggcgggcgactttgactcctggggccagggactcctggtcaccgtctcatctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11295 JY8QFUQ01AEJQ0 productive Homsap IGHV1-2*02 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [0.17.38.11] CARDGRGFSYGENLDHW in-frame + tggatacagcttttccggctactatatacactgggtgcggcgggcccctggacaagggcttgagtggatgggatggatcaaccctaacagtggtggcccagaatatgcacagaaatttcagggcagggtcaccatgaccagagacacgtccaccaccacagcctacatggaaataatcaggttgacatctgacgacacggccgtctattactgtgcgagagatggccgtggattcagttatggtgagaaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtcagggcttcttccccc +11296 JY8QFUQ01CC0ZG unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [1.17.38.11] CASFRVLESGY## out-of-frame + tctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactgggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11297 JY8QFUQ01CF5AI productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1007 94.64 212/224 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD6-19*01 F 3 8 10 11 8.10.11 [1.17.38.11] CTTDIVSQWPVRW in-frame + cctctggactcagtttcactaacgcctggatgagctgggtccgccaggctccggggaaggggctggagtgggttggccggattaaaagcaaaactgatggtgggacaacagagcacgctgcacccgtgaaaggcagattcaccatctcaagagatgactcaaaaaacacgctgtatctgcaaatgaacagcctgaaaaccgaagacacaggcgtttattattgtaccacagatattgtctcccagtggccggtgcgctggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11298 JY8QFUQ01AHGN8 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactgggaccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactc +11299 JY8QFUQ01A5DW7 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 401 77.21 105/136 nt 76.47 104/136 nt 8 6 X 8.6.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (77,21% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) cctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11300 JY8QFUQ01CRGV4 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1060 100.0 213/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - tctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11301 JY8QFUQ01AW1SP productive Homsap IGHV3-48*03 F 883 89.5 196/219 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARESWWSGFYGWYDPW in-frame - gcctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11302 JY8QFUQ01CNY5Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11303 JY8QFUQ01BCWQ9 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); agtttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11304 JY8QFUQ01BB1MS No results +11305 JY8QFUQ01BYIEM productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 878 89.45 195/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD2-2*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDRTLHTPAQMFYYGMDAW in-frame - cctctggatttaccttcagttcttatagtgtcaactgggtccgccaggctccagggaagggcctggagtgggtctcatatattgataatagtggttctaccatatattatgcagactctgtgaagggccgattcaccatctccagagacaatgcccagaactcactgtttctgcaaatgaacagcctgcgagccgaggacacggccgtttattactgtgcgaaagatcggacactacacacacccgctcagatgttttattatggtatggacgcctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11306 JY8QFUQ01AOS3H No results +11307 JY8QFUQ01ADJ6A productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 723 82.24 176/214 nt 81.78 175/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'T' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); ctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatcTattccctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagagcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11308 JY8QFUQ01CNFA2 No results +11309 JY8QFUQ01BRW0B productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 860 88.53 193/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CTRVGTFNWFGPW in-frame + cctctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +11310 JY8QFUQ01DFGEE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.37.11] CAKDASRYYYNSYCDNW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 214 in the user submitted sequence), (cause frameshift) cctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttattttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11311 JY8QFUQ01ASDGB productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 856 88.13 193/219 nt 87.21 191/219 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [2.17.37.11] CVSDRELHYQHLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 161 in the user submitted sequence), (cause frameshift) agcgtctggattcaacttcaatagttTttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11312 JY8QFUQ01CR9KI unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF## out-of-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggcccagggagtcctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcaccctagccagatgggaacgtggtcatcgcctgcctggtccagggtcttcttccccca +11313 JY8QFUQ01CK7SR productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11314 JY8QFUQ01B7VBT productive (see comment) Homsap IGHV4-61*02 F 890 90.7 195/215 nt 87.44 188/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 7 13 8.7.13 [2.16.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'CTGGTT' (6 nucleotides at position 23 to 28 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 130 to 130 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 219 to 219 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) gtctccggtggctccatcagtaCTGGTTattactactggGagctggatccggcagtccgccgggaagggactgaatggattgggcgcatgtctgccagagggggAcagcaactacaaAcccctccctccCagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtaCtttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11315 JY8QFUQ01BP74B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccaatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcanttccccgaaccggtgacggtgtgcgtggaactcag +11316 JY8QFUQ01BPU8S productive Homsap IGHV3-48*01 F 923 91.74 200/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGNYYYFGMDVW in-frame + cctctggattcctcttcagtagctttaacatgaactgggtccgccaggttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccatctactactgtgcgagacaaactgggaattattattacttcggtatggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11317 JY8QFUQ01AY1CD unproductive Homsap IGHV3-9*02 F 901 90.41 198/219 nt Homsap IGHJ2*01 F 85 62.26 33/53 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [2.17.38.11] CGKDMRPGGMD#LG out-of-frame - gcctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctgggggccagggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11318 JY8QFUQ01CHTKO unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRGLY*WCMLCR#DFW out-of-frame + stop codons cctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggcttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11319 JY8QFUQ01CBZC1 unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 817 85.14 189/222 nt 84.68 188/222 nt 8 10 X 8.10.X [1.17.37.X] null + No rearrangement found in FR3-IMGT, from codon 94 of V-REGION: 2 nucleotides (from position 194 in the user submitted sequence), (cause frameshift) tctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgatgtcgtggaactcag +11320 JY8QFUQ01CQKGX unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 84 51.52 68/132 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons cctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccaaggtcttcccgctgagcctctgcagtacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +11321 JY8QFUQ01BM2JY productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + ctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +11322 JY8QFUQ01C6LCV unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 8 14 8.8.14 [1.17.38.11] CARGL*ER*WWSLPQE (see Functionality comment) in-frame - stop codons, IMGT/JunctionAnalysis gives no results for this JUNCTION catctggactcaccttaagtacttatgacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatctggtctgattgaagtaataaatattatgcagactccgtgaagggccgattcaccatctccagagacaaatccaagaacacgctgtatttgcatatgaacagcctgacagccgaggacaggactgtgtctgactgtgcgagaggcctgtaggaacgataatggtggtcactaccccaggaaagccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11323 JY8QFUQ01DKS16 productive (see comment) Homsap IGHV4-59*03 F 844 88.73 189/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.16.38.11] CARGRTVVTVIDYMDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 45 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift) tctctggtggActccattagcggttactattggacctggatccggaaaccccaggaaagggactgagtggattggaaatatccactacagtgggagcaccaagtacagtccctccctcaagagtcgagtcaccatatcactcgccacgtccaagaatcaattcgccctgaagttgacctctgtgaccgctgcggacacggccgtctattattgtgcgagaggacgaacggtggtgactgttattgactacatggactactggggtcagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11324 JY8QFUQ01BVZ1U unproductive Homsap IGHV4-61*02 F 920 90.95 201/221 nt 90.5 200/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD2-21*01 F 3 10 7 X 10.7.X [1.17.38.11] CAREKGSDPS#NWFDPW out-of-frame + in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tctctggtgactccatcaccagtggtaattattattggagttggatccggcagcccgccgagaagggactggagtggattgGggcgtatctccatcggtgggatcaccaactacaatccctccctcaagagtcgagtcaccatactattagacacgtccagcaaccggttctccctgaagctcagctctgtgaccgccgcagacacggccgtgtattactgtgcgagagaaaaaggtagtgatccgtcccaattggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +11325 JY8QFUQ01DLSH2 No results +11326 JY8QFUQ01A13KG unproductive Homsap IGHV3-48*03 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD1-1*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGSLGSG#DHW out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); tctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggGggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgaacagcctgagagccgaggacacggccgtattttactgtgcgaggggctcgctcggttcgggtgggaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +11327 JY8QFUQ01B624X No results +11328 JY8QFUQ01BNE9H unproductive Homsap IGHV3-66*02 F 881 90.23 194/215 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [1.17.38.11] CAALHDPPWGWLD#PG out-of-frame + cctctggattcagcgtcaacaacaactacatgaactgggtccgcctggctccagggaagggtctggagtgggtctcagttatttatagaggtggtaatacattctacacagactccgtgaagggccggttcaccatctccagagacatttccaagaacactttgtatcttcaaatgaacagtctgacaactgaggacacggctgtgtactattgtgcggccctccacgaccctccttggggttggctcgacccctggggccggggaaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11329 JY8QFUQ01BIB1C No results +11330 JY8QFUQ01CT766 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaagactacttcccccgaaccggtgacggtgtcgtggaactcag +11331 JY8QFUQ01BUIPP productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt 98.62 214/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'CA' (2 nucleotides at position 82 to 83 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctatagcatgaactgggtccgccaggctccagggaagGgggctggagtgggtctcatccCAattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11332 JY8QFUQ01AXFX6 productive Homsap IGHV3-64*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +11333 JY8QFUQ01B7KJV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDTRMAAAGSGFDCW in-frame + ctctggattcacctttagtcgctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctctacttttggtattagtgagggtgacacatactacgccgactccgtgaagggccggttcaccgtctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagtcgaggacacggccacatactactgtgcgagagacactcgtatggcagctgctggttcagggtttgactgctggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11334 JY8QFUQ01DMW84 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDPSGSGWAFESW in-frame + gtctggattccctttcagtagagatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatggtatggtatgatggaagtaatacacaccatgcagattccgtgaagggccgattcatcatttccagagacaattccaagaataaagtgtatctgcaaatgaacagtctgagagacgaggacacggctgtctattattgtgcgagagatccgagcggcagtggctgggcctttgagtcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11335 JY8QFUQ01DV2TG unproductive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARETLPLGVGG#LDNW out-of-frame + stop codons ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggtttttagacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +11336 JY8QFUQ01CSHGI productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVKGAGTTVNWFDIW in-frame - cctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11337 JY8QFUQ01CQZTC productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11338 JY8QFUQ01CHVJ1 productive (see comment) Homsap IGHV3-7*02 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) tctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11339 JY8QFUQ01DERJL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARERSAAGVVFFDFW in-frame - cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagagagatcagcagctggagtcgtcttctttgacttttggggccagggagccccggtcaccgtctccagagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11340 JY8QFUQ01DU6KV unproductive Homsap IGHV3-9*01 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CVKDRKAGGYNLLDAFDI## out-of-frame - in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); ctctggattcaccttcgacgactatgtcatgcattgggtccggcaagttccagagaggggcctggagtgggtcgcaggcattaatggggaaagtaatagAttttggctctgtggactctgtaaagggccgattcaccatctccagagacaaggccaagaataccctgtatttgcaaatgaatagcctgagagttgaggacacggccttgtattattgtgtgaaagatagaaaagctggtggctacaatctgttggatgcttttgatatctggggccagggaacccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11341 JY8QFUQ01A75KS No results +11342 JY8QFUQ01B5RK2 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 98 52.63 70/133 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11343 JY8QFUQ01CSZGR unproductive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 10 7 X 10.7.X [1.17.38.11] CATIVPSSVTALINDQGRFYFDH## out-of-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11344 JY8QFUQ01DEUP9 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 651 99.25 132/133 nt 98.5 131/133 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD2-2*03 F 2 8 X X 8.X.X [1.11.24.11] CAKFMGVVVVPAAHNWF#PL out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 50 of V-REGION: 84 nucleotides (from position 62 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaagggagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagcagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11345 JY8QFUQ01BQOBI productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11346 JY8QFUQ01DTPOY unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +11347 JY8QFUQ01DGJE0 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctgggtggctccatcagtagttactactggagctggatccggcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11348 JY8QFUQ01CEOFM No results +11349 JY8QFUQ01CWOYG productive (see comment) Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 99.07 214/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 73 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaaggggctggagtgggttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11350 JY8QFUQ01CTDFC unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 97 52.14 73/140 nt 10 9 X 10.9.X [1.17.9.X] null - No rearrangement found stop codons tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11351 JY8QFUQ01CSVFI productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-NL1*01 F 844 88.73 189/213 nt 88.26 188/213 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [1.17.38.11] CTRELRVAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggGggctggagtgggtctcagtaatttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11352 JY8QFUQ01BRGH5 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 868 89.35 193/216 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [1.17.38.11] CACGHMRDGYDVW in-frame - tctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11353 JY8QFUQ01BP7RX productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11354 JY8QFUQ01C1094 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.16.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaagggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11355 JY8QFUQ01AS600 productive (see comment) Homsap IGHV3-48*01 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); tccggattcaGatttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgga +11356 JY8QFUQ01ACLAL productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame - tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11357 JY8QFUQ01DB8G8 No results +11358 JY8QFUQ01DA3VW unproductive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1110 100.0 223/223 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFLDY## out-of-frame + ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttactttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggctgtcgtggaactc +11359 JY8QFUQ01BZFMX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 824 86.7 189/218 nt Homsap IGHJ1*01 F 206 88.46 46/52 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAAVGVGSAVSFQYW in-frame - cctcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctctagagacacctccaagaacacgttatttcttcaaatgaataccctaagaggtgaggacacggctgtgtactactgtgcggcagtcggagtgggaagtgcagtctccttccaatactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11360 JY8QFUQ01DL31Y unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1012 96.76 209/216 nt 95.37 206/216 nt 7 8 X 7.8.X [1.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift) ctctggattcaGccttcagtagtataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaaggGgccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggaggggggcgagccgcttgaccactgggggccagggaacccctggtcagcgtctccctctgcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11361 JY8QFUQ01C66OW productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11362 JY8QFUQ01A2OGP unknown (see comment) Homsap IGHV1-3*01 F, or Homsap IGHV1-3*02 F (see comment) 270 64.05 98/153 nt 8 8 X 8.8.X [0.17.17.X] null + No rearrangement found Low V-REGION identity (64,05% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggattcaccttcactgactatgctatgcattgggtgcgccaggcccccggacaagggcttgagtggatgggatggatcaacgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +11363 JY8QFUQ01BYFKL No results +11364 JY8QFUQ01DS6VV productive (see comment) Homsap IGHV1-3*01 F 822 87.38 187/214 nt 86.92 186/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [0.17.38.11] CVRGRSPPGDWFDPW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); tggatacaccttcactaAtttatgctctgcaatgggtgcgccgggcccccggacaaacttttgagtggctgggatggatcaactctgccaatggcaacacaaaatattctcagaagtttcagggcagagtcgccattaccagggacacatccgcgaggacaacttacatggaattgagcagtctgacatctgaagacacggcgacatattattgtgtgagaggaagaagtccgcccggcgactggttcgacccctgggggccagggaaccctgtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11365 JY8QFUQ01AJ9AF No results +11366 JY8QFUQ01C1CFQ productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); gtctggattcacgtttagtagAttttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcagtcttcccccatggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11367 JY8QFUQ01DRRGP productive Homsap IGHV3-7*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + cctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctcag +11368 JY8QFUQ01CBP62 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11369 JY8QFUQ01C7P5K productive (see comment) Homsap IGHV3-7*01 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-3*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDDDFWNGKHFDPW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 85 in the user submitted sequence), (cause frameshift) ctctggattcagtcttaataactactggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaatataaaaaagatggaagtgagaaatactatgtggactctgtgaagggccgtttcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagaggcgaggacacggctgtgtatcactgtgcgagagacgacgatttttggaatggtaaacacttcgacccctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11370 JY8QFUQ01C73KI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.78 201/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.17.38.11] CAKDMGGDYYIFHYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); gcttctggattctcctttagcaacnatgccctgggcCtgggtccgccaggctccagggaaggggctggagtgggtctcaattgttagtggaagtggtactggcacaggccacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggatatgggtggcgactattacatctttcactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11371 JY8QFUQ01AT23W unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 1 8 8 X 8.8.X [1.17.38.11] CAREGGGAVRRK#YFDYW out-of-frame + ctctggattcaccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaatggtgcttacatatactacgcagactcaatggagggccgattcaccatctccagagacaacgccaggaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgcgagaggggggcggggcagttcgtcggaagactactttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11372 JY8QFUQ01B9QWJ unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 914 91.28 199/218 nt Homsap IGHJ3*02 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDQMSGGMPEA#FDIW out-of-frame + cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaatgtctgggggcatgcccgaggcttttcgacatctggggccaagggacaatggtcaccgtctcctcaggccctcaccaaatgggccccaatcggtttccccccttggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaacggtgacggtgtcgtggaactca +11373 JY8QFUQ01CNIRS productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11374 JY8QFUQ01B4R6M No results +11375 JY8QFUQ01CCPBN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCGNGACHVADYW in-frame + ctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11376 JY8QFUQ01A5BG8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 938 93.87 199/212 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 3 7 8 X 7.8.X [X.17.38.11] CAKLSGGGSTY#FDYW out-of-frame - gattcacctttaacaactatgccatgagctgggtccgccaggctccgggggaggggctggagtggctctcaactgttagtggtcgtggtgacagcacatactacgcagactccgtgcagggccggttcatcatctctagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaactgtcgggcgggggcagcacgtaccctttgactactggggccagggaaccctggtcacagtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11377 JY8QFUQ01BJN3B productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 868 89.35 193/216 nt 88.43 191/216 nt Homsap IGHJ1*01 F 215 90.38 47/52 nt Homsap IGHD5-12*01 F 3 8 7 14 8.7.14 [2.17.38.11] CASGGYSGSGEYFLRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); gcctctgacttaaTcggtcagtgacaattacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacggttcccagaacacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtaCtttttgtgcgagtggtggttattcgggctcgggtgaatatttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11378 JY8QFUQ01DWSY6 productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaTggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11379 JY8QFUQ01AZHXN No results +11380 JY8QFUQ01CT4CD unproductive (see comment) Homsap IGHV4-61*02 F (see comment) 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 X 10.7.X [1.17.37.11] FVEKSLL*QFAPAL#DYW out-of-frame - stop codons Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) ctctggtgcctccatcaacagtggtagttactactggagttgggttcggcagcccgccgggaagggactggagtggattgggcgtatctacaccagtgggagcaccaactacaaccctccctcaagagtcgagtcgccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctaattttttgtcgagaaatccctcttatagcaattcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11381 JY8QFUQ01AKFBE productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + ctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccag +11382 JY8QFUQ01AN9EC unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 752 83.03 181/218 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CARTPCSGGNCYLRGHDL# out-of-frame - Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcgggtatttattattgtgcgcggacgccttgcagtggtggaaattgttaccttagaggccacgacctctgggccagggaacccaggtctccgtttccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11383 JY8QFUQ01DK6RA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 7 8 X 7.8.X [1.17.38.11] CAKQNIVM#YYFDQW out-of-frame + in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) tctggattcacgtttaaacacatgccatgagctgggtccgccaggctccaggaaaggggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaacatagttatggatactactttgaccagtggggccagggaacccgggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +11384 JY8QFUQ01DPFIO productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 973 94.06 206/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [2.17.38.11] CAKGDSGGYTHNYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaAggggctggtgtgggcctcacgtgttaatggtgatAgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattactgtgcaaaaggggatagtggtggttatacccacaactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11385 JY8QFUQ01B403G unknown (see comment) Homsap IGHV4-59*10 F (see comment) 440 66.98 144/215 nt 66.51 143/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null - Rearranged sequence but no junction found The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01B403G ; 8 AA in Homsap_IGHV4-59*10), and low V-REGION identity (66,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT at codon 63 of V-REGION: 'AGAACAATCTCTTCAATACCTCCCTCAGGAGTC' (33 nucleotides at position 100 to 132 in the user submitted sequence), (do not cause frameshift); ttctggctggcgccatcagcgatattggctccttctggagctgggtccgacagcccgccgggagttcgctggagtacatcggacgtgtctataatagtgAGAACAATCTCTTCAATACCTCCCTCAGGAGTCgaatcaccaactacaatcctgccctaaggagtcgagtcaccatgtcagtggacacgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11386 JY8QFUQ01AG01M productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARALIVVAGAPVYWG in-frame + ctctggattcaccttcagtagttatagtatgatctgggtccgccaggctccagggaaggggctggagtgggtcgcttcaattagtcataccgggggttccaaatattacggagactcactgaagggccgattcgccatctcaagagacaacgacaagaactcactgtatctgcaaatgaccagcctgagagccgaggacacggctgtctactactgtgcgagagccctaatagtagtggctggtgcccctgtctattgggggccaggggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11387 JY8QFUQ01A56OJ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11388 JY8QFUQ01CAQG8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctaggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11389 JY8QFUQ01DOY4X No results +11390 JY8QFUQ01A3OUD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +11391 JY8QFUQ01BVTC6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + tctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +11392 JY8QFUQ01BC28P productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11393 JY8QFUQ01BK9R4 No results +11394 JY8QFUQ01B5TTD No results +11395 JY8QFUQ01DTFKX No results +11396 JY8QFUQ01BXBPF productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 932 92.2 201/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + cctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11397 JY8QFUQ01BUHVK No results +11398 JY8QFUQ01CY3RH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11399 JY8QFUQ01BIWOC productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1030 95.56 215/225 nt 95.11 214/225 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 1 10 9 13 10.9.13 [1.17.38.11] CVRDVGWGLDTLDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tccggggacactgtctctagcaacagtgctgcttggaactggatcaggcagtCccccatcgagaggccttgagtggctgggaaggacatattacaggtcccagtggtattatgattatgcagtgtctgtgcagagtcgaataaccatcatcccagacacatccaagaaccagttctccctgcagttgaactctgtgattcccgaggacacggctgtgtattactgtgtaagagacgtcggctggggattggatactcttgatatctggggccaagggacaatggtcatcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +11400 JY8QFUQ01BEXDZ unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-59*08 F or Homsap IGHV4-61*01 F 962 94.42 203/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 3 8 7 X 8.7.X [1.17.38.11] CAKNLWLRTR#YW out-of-frame + tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgaaaaatctctggctacggacaaggctactggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11401 JY8QFUQ01CK138 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttggttattatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +11402 JY8QFUQ01AJ1GW No results +11403 JY8QFUQ01AI8GD productive (see comment) Homsap IGHV3-7*01 F 1009 95.89 210/219 nt 95.43 209/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); ggctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11404 JY8QFUQ01BDI1Z productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARVDFYGSSKYKGFDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); tctctggtaactccatcacagattattactggagctggctccggcagtctccagggaagggactggagtggattggaaatgtcCttttacagtgggagagccaactacaacccctccctcaagagtcgagtcaccatatcagtagccacgtccaggaaccagttctccctgaagctcaggtctgtgaccactgcggacacggccatatattattgtgcgagagttgatttctatggttcgagtaaatataaggggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcgatcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11405 JY8QFUQ01AZUUS productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11406 JY8QFUQ01AC0DA productive Homsap IGHV3-48*01 F 980 95.35 205/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARERGNSYGEIDYW in-frame - ctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaagactacttccccgaaccggtgacggtgtcgtggaactcag +11407 JY8QFUQ01C6P75 unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 7 8 X 7.8.X [1.17.38.11] CARDMGSGRYLNL#DYW out-of-frame - in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) ggtctggattcatcttcttgaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatatttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11408 JY8QFUQ01BQ2SE No results +11409 JY8QFUQ01AORVQ No results +11410 JY8QFUQ01BHBH9 unproductive Homsap IGHV4-4*07 F 835 88.26 188/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 3 8 7 X 8.7.X [1.17.38.11] CARSGWDNQ#DFW out-of-frame + in CDR1-IMGT at codon 37 of V-REGION: 'GCACTT' (6 nucleotides at position 23 to 28 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); tctggtgtcgccaccagtagtgGCACTTactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaaccCcctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaattgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11411 JY8QFUQ01C0QXR No results +11412 JY8QFUQ01AESJ4 unknown (see comment) Homsap IGHV3-7*02 F 118 60.24 50/83 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found cctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11413 JY8QFUQ01AJ7GQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcacctttagcaactatgccatgagttgggtccgccaggctcaagggaaggggctggactgggtctcagatattagtaatagtggtggtgacacattctacgcaggctccgtgaagggccgcttcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcacgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccagg +11414 JY8QFUQ01CQ1NV unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F (see comment) 660 78.97 169/214 nt 78.5 168/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [0.17.38.11] CARERRPGGYPNGYHHFYGMDV## out-of-frame + Low V-REGION identity (78,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); ctctgatacaattagtcgttatggcatgcactgggtccgccaggctccaggcaaggggctggagtggctggGcaattatttcatatgatggaaataggatatatgttggagactccgtgaagggccgcttcaccgtttccagagacaacgtcgggaggactctgtttctgcaaatgaacagtctgagaggtgatgacaccgccacatatttttgtgcgagagagcggcgtccgggtggctatccaaatggctaccaccatttttacggcatggacgtctggggccaaagggaccagggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11415 JY8QFUQ01AX4LK No results +11416 JY8QFUQ01CQ37A productive (see comment) Homsap IGHV2-5*02 F 1021 91.36 222/243 nt 90.12 219/243 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 18 10.7.18 [9.17.38.11] CAHNSLYDRNGYYLTYFDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 27 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 152 to 152 in the user submitted sequence), (cause frameshift); accctcacactgacctgcaacctctctGggggtctcactcagcagtcgtggagtgggtgtgggctggatccgtcaggccccaggAaaaggccctggagtggcttgccctcattgattgggatgatgacaagcgctatagtccatctctaaaCggggaggctcaccatcaccagggacacctccacaggccaggtggtcctcacaatgaccaacatgcaccctgtggacacagccacatattactgtgcacacaacagtctctatgataggaatggctattatttgacgtactttgatcactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11417 JY8QFUQ01B4BNR No results +11418 JY8QFUQ01B59I4 No results +11419 JY8QFUQ01CQS64 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11420 JY8QFUQ01AOCOZ productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); gtctggattcacgtttagtagAttttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +11421 JY8QFUQ01DTVBR No results +11422 JY8QFUQ01DO95W No results +11423 JY8QFUQ01A1C30 unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAREVKYGDDTGG#WFDPW out-of-frame + gtctggattcaccttcagtgactctggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcacttatatggtatgatggatattataaacaacatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattactgtgcgagagaggtgaaatacggtgacgacacgggggggatggttcgacccctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgggtccagggcttcttcccccag +11424 JY8QFUQ01BB8AU productive Homsap IGHV3-66*02 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 12 8.7.12 [1.17.38.11] CARQTAPFGYFEDW in-frame + ctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatatcagtggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaagaacacggtgtatcttcagatgaacagtctgagagctgaggacacggctgtgtattactgtgcgagacagactgccccttttgggtactttgaggactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +11425 JY8QFUQ01A9H3D unknown (see comment) Homsap IGHV3-13*01 F (see comment) 361 67.63 117/173 nt 8 7 X 8.7.X [1.17.24.X] null - No rearrangement found stop codons Low V-REGION identity (67,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ccgctggattcaccctcagttcctacgacatgcactgggtccgccagactacaggaaaaggtctggagtgggtctcaggtataagcactgacggtgacacatactattcaggctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11426 JY8QFUQ01CS771 productive (see comment) Homsap IGHV4-61*01 F (see comment) 759 84.11 180/214 nt 83.64 179/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 1 8 7 13 8.7.13 [2.16.38.11] CASVRPSGERFFDFW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 37 of V-REGION: 8 nucleotides (from position 31 in the user submitted sequence), (cause frameshift) gtctctggtggctcgctcacgggttcaagtgggctggatccggcagcccccaggggagggactgcaatggattggacatatctctttcgttggggacaccagttatgacccttccctcaggagtcgagtcaccatttcagtcgacacgtccaagaaccagttctccctgaaactgaactctatgactcctgcggacacggccgtctattactgtgcgagcgtgcgtccttcgggagaacggttcttcgacttctggggcctgggaaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11427 JY8QFUQ01BP1DC unproductive Homsap IGHV3-48*02 F 995 95.41 208/218 nt 94.5 206/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGEGDPFF##YYSGLDVW out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaGggggctggagtgggAtttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11428 JY8QFUQ01DHNAH productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'T' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccTttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11429 JY8QFUQ01AQ0RE productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11430 JY8QFUQ01BKBKE productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 136 76.6 36/47 nt Homsap IGHD2-15*01 F 1 8 8 6 8.8.6 [1.17.38.11] CASLPLVW in-frame - ttttaattacaacgttaccacctactggatgggctgggtgcgccagaagcccggaaaaggcctggagtcgatgggaatcatctatcctggtgactccgatgtcaggtacagtccgccctttcaaggccaggtcaccatgtccgtcgacacgtccaccaatgtcgcctacctgcagtggaacagcctgaaggcctcggacaccgccatgtattattgtgcgagtctcccccttgtctggggccaggggacaatggtcaccgtcgcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11431 JY8QFUQ01AEPDX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-17*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKEMIRYGDDVFGGLNVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggatttacctttagcagttatgccatgaactgggtccgccaggctccagggaaggggctgcagtgggtctctggtattagtggtggtggtgatgacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtgtattactgtgcgaaagaaatgatccgctacggggacgacgtttttggcggtctgaacgtctggggccaagggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +11432 JY8QFUQ01AZ3LY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11433 JY8QFUQ01ATPQS productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11434 JY8QFUQ01CQ508 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11435 JY8QFUQ01C2PD8 No results +11436 JY8QFUQ01BDHZ7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaac +11437 JY8QFUQ01AWF3H unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +11438 JY8QFUQ01A2TQ5 No results +11439 JY8QFUQ01CEBF1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11440 JY8QFUQ01DQQIL No results +11441 JY8QFUQ01C2J6R productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggCtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11442 JY8QFUQ01C4B5M No results +11443 JY8QFUQ01ATW8E unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 777 85.05 182/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CARERGSGPP#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaagaggttcgggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11444 JY8QFUQ01CZOCG unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDQSCIVGPCG#FDYW out-of-frame + stop codons ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggtttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagaacacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11445 JY8QFUQ01DK4P3 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1020 97.66 209/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARGGGYYFVAIDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +11446 JY8QFUQ01CTMRO unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSDFYSTGH## out-of-frame + in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); ctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgTtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11447 JY8QFUQ01C0NG5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactc +11448 JY8QFUQ01DKKI3 No results +11449 JY8QFUQ01AUE9D productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); cctctggattcaccttcCgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11450 JY8QFUQ01AAW35 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 914 91.28 199/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - cctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11451 JY8QFUQ01AMSPO productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1025 97.67 210/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARGGGYYFVAIDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +11452 JY8QFUQ01CXZV1 No results +11453 JY8QFUQ01A7XDX productive Homsap IGHV3-7*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - ctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11454 JY8QFUQ01BZLHT unproductive Homsap IGHV3-48*01 F 945 93.09 202/217 nt Homsap IGHJ1*01 F (see comment) 116 69.23 36/52 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYFEPYDY# out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactgggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11455 JY8QFUQ01B252D productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 800 86.05 185/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 3 8 7 15 8.7.15 [1.17.38.11] CARLAMLRGVPTWFDPW in-frame - cctctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactcagtgaagggccgattcaccatctccaaagacaacgccaaaaacttattgtttttgcaaatggacagcctgagagacgaggacacggctatttattactgtgcgagacttgcaatgcttcggggagtccccacctggttcgacccctggggccagggagccctagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11456 JY8QFUQ01B6832 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.37.11] CARDPRDYCSGGYCFVGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 92 of V-REGION: 1 nucleotides (from position 177 in the user submitted sequence), (cause frameshift) tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +11457 JY8QFUQ01B996S No results +11458 JY8QFUQ01AZZ4J No results +11459 JY8QFUQ01ARI4W productive Homsap IGHV4-39*03 F 919 91.28 199/218 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - tccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11460 JY8QFUQ01BYVHP No results +11461 JY8QFUQ01CMEMC productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 900 90.78 197/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) ggcctctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11462 JY8QFUQ01BU88H productive (see comment) Homsap IGHV3-48*02 F (see comment) 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [2.17.38.11] FVTERGGGLLRYLDLW in-frame - Potentially, because of detected insertion/deletion Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); ggctctggattcatgttcggtagttatagtctgaattgggtccgccaggctccagggaaggGggctggagtggatttcatatattagtagcagtagtcaaacgatttactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgcgagacgacgacacggccatttactactttgtgacagagaggggcgggggcctattacgatatttggacttatggggcctgggaactcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11463 JY8QFUQ01DF59O No results +11464 JY8QFUQ01DM3BG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11465 JY8QFUQ01DM1S8 productive (see comment) Homsap IGHV4-59*03 F 791 85.58 184/215 nt 84.65 182/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.37.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 86 of V-REGION: 'C' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) gtctctggtgactccattagtggttactattggacgtggatccgacagcgcccagggatgagcctggagtggattggacaagtccattacactgggagcaccaagtacagccctccctcaagagtcgagtcaccatttctgttgacatgtccaagaaccCaattcaccctcatcttgacctctgtggccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11466 JY8QFUQ01CHP9C No results +11467 JY8QFUQ01CHIXP No results +11468 JY8QFUQ01B5DKA No results +11469 JY8QFUQ01CULC9 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 412 88.46 92/104 nt 87.5 91/104 nt 8 8 X 8.8.X [1.16.1.X] null - No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 47 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggagggggctggagtgggtctcagccattagtggcagtggtagtcggacatatt +11470 JY8QFUQ01COX54 No results +11471 JY8QFUQ01BRZGC No results +11472 JY8QFUQ01AUPN6 productive (see comment) Homsap IGHV4-59*03 F 1025 97.67 210/215 nt 96.74 208/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARGLRWNDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaatCagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatgcctattacagtgggagcaccaactacaAacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccaattctccctgaagctgacctctgtgaccgctgcggacacggccgtctattactgtgcgagagggttgcgttggaacgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11473 JY8QFUQ01AZGCF No results +11474 JY8QFUQ01DB35I unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 801 85.25 185/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDNVTF#DAFDIW out-of-frame - gtctgggttaaccttcagtgaggatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagtcatttggaacaatggaaagacctttcactatgcagactccgtgaagggccgcttcgtcatctcccgagacaattccaagagcaccctatatttacaaatgaatagcctgagagtcgaggacacggctgtgtattactgcgcgagagataatgtcacctttgggatgcctttgatatttggggccgggggacaacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11475 JY8QFUQ01ATN66 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.16.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'A' (1 nucleotides at position 208 to 208 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccaggaaggggctggagtgggtctcaggtattagtggtagtggtgAaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccAgtttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11476 JY8QFUQ01ANTFH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11477 JY8QFUQ01ADPMB No results +11478 JY8QFUQ01AQ0K4 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 896 90.37 197/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 17 to 18 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ggcctctggattcaccCTttgggttattatggcatggactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11479 JY8QFUQ01CRDUG No results +11480 JY8QFUQ01CE4MI productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1105 100.0 222/222 nt 99.55 221/222 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD6-6*01 F 2 8 10 16 8.10.16 [1.17.38.11] CTRRSIADNFYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); tctgggttcaccttcagtggctctgctatgcactgggtccgccaggcttccgggaaagggctggagtgggttggccgtattagaagcaaagctaacagttacgcgacagcatatgctgcgtcggtgAaaaggcaggttcaccatctccagagatgattcaaagaacacggcgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtactagacggagtatagcagataacttctactactacggtatggacgtctggggccaagggaccacagtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11481 JY8QFUQ01DDE64 productive Homsap IGHV3-21*04 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARVRGYYGGQYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11482 JY8QFUQ01BXFLK unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARVGYGYRGIYFFDY## out-of-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11483 JY8QFUQ01CV33N No results +11484 JY8QFUQ01AVMKB productive Homsap IGHV3-11*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +11485 JY8QFUQ01CE7YT productive Homsap IGHV3-9*01 F (see comment) 788 84.86 185/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CGRIAKPGLGALDLW in-frame - Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcgttggattcacttttaatgaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctggggccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11486 JY8QFUQ01DOIZU productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1002 96.73 207/214 nt 94.86 203/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARTTSSSGWYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); ctctggaggctCccattagtaattactacCtggagttgGgatccggcagcCccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaatcagttcttcctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgaggactacttctagtagtggctggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11487 JY8QFUQ01DJQ5C productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 841 89.86 186/207 nt 89.37 185/207 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 30 of V-REGION: 8 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) tctctggtgactccccacttctggagctggatccggcagcccccgggaaagggcctggagtggattggttatgtctataacagtgggaccaccaactacaacccctccctcaggagtcgagtcaccatgtctatagacacgtccaagaagcagatctctctgaggttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactcctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccag +11488 JY8QFUQ01AL2FG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11489 JY8QFUQ01BX5EO unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 7 X 8.7.X [1.17.38.11] CATLRGGY#FDYW out-of-frame + tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggctactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttcccccgaacccggctggacggtgtcgtggaactcag +11490 JY8QFUQ01BMIPQ unproductive Homsap IGHV4-61*02 F (see comment) 560 72.85 161/221 nt 72.4 160/221 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD3-10*01 F 1 10 7 X 10.7.X [1.17.38.11] CARECSNSKVGPRALDS## out-of-frame + Low V-REGION identity (72,85% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'CGG' (3 nucleotides at position 60 to 62 in the user submitted sequence), (do not cause frameshift); tttctggtggcccgatcaaaagtcctgattaccattggacgtggatccggcagccccgcCGGggaaggggactggagtgggtcggacgtgtctatatgactggttatgtcgaccacaatccatccctctccgggcgtctcaccatgtctatcgacacctcgaagaatcaattttctatgacattgacctctgtgaccgccgcagacacggccctatatttttgtgcgagggagtgtagtaattcgaaggtcggaccgagagcgcttgattcctggggccccgggaagtctggtcaccgtatcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11491 JY8QFUQ01CGGNW unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11492 JY8QFUQ01BK1LC No results +11493 JY8QFUQ01BFVM4 productive Homsap IGHV3-30*01 F 860 88.53 193/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacccgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactactttcccgaaccggtgacggtgtcgtggaactc +11494 JY8QFUQ01DIAT7 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 945 93.09 202/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 1 8 8 19 8.8.19 [1.17.38.11] CARKWPPEEMAPLQQCDMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaatggcccccagaagagatggctcccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgcacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +11495 JY8QFUQ01CUR2C productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11496 JY8QFUQ01AP3IL No results +11497 JY8QFUQ01AWNB8 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 914 91.28 199/218 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcacctttgatgattttggcatgagatgggtccgccaagtcccagggaaggggctacagtgggtctctgggattaattggaatggtgctaaaacaggttatgcagcctctgtgcagggccgattcaccatctccagagacaacgacaacaacgtcctgtatctgcaaatgaacagtttgagacccgaggacacggccttgtatcgctgtgcgagagaggtttcggacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccc +11498 JY8QFUQ01CWCXK unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +11499 JY8QFUQ01CKOQL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11500 JY8QFUQ01B8FNM unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaagccctggctnaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +11501 JY8QFUQ01DJM48 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 872 89.77 193/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11502 JY8QFUQ01BAFIL No results +11503 JY8QFUQ01CHNO7 productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaactc +11504 JY8QFUQ01A9N1H No results +11505 JY8QFUQ01AVKBO No results +11506 JY8QFUQ01DQ94B productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + gtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +11507 JY8QFUQ01BBMAT No results +11508 JY8QFUQ01A29HR productive (see comment) Homsap IGHV3-11*01 F 828 87.1 189/217 nt 86.18 187/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CVREVTGVWDWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'A' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); ctctggattcaccttcaaAggactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtgGgtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctggcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +11509 JY8QFUQ01DMVW5 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11510 JY8QFUQ01CGMRL productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 900 90.78 197/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + gtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccacaagggcccatcggtcttcccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +11511 JY8QFUQ01BERLC unproductive Homsap IGHV3-11*01 F 878 88.99 194/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARGPHSYASDGHNFDF## out-of-frame - Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcagcttcagtgactattacatgggttggatccgccaggctccagggaaggggctggagtggcttgcatatattactagtaccagtgccaccatatattatgcagactctgtgaggggccgattcaccacctccagggacaacgccaaaaactcactgtatctgcacataaacagcctgagagtcgaggacacggccgtttattactgcgcgagaggtccccattcctatgccagtgatggtcacaattttgacttctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11512 JY8QFUQ01BJM8B unknown (see comment) Homsap IGHV1-2*02 F 503 86.47 115/133 nt 8 8 X 8.8.X [0.17.11.X] null + No rearrangement found tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaacc +11513 JY8QFUQ01DRXN2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARDILGATRFDYW in-frame - cctctggattcaccttcagcagctatgccatgagctgggtccgccaggctccagggaagggcctggagtgggtctcagctattagtggtattggtgggagtacattctacgcagactccgtgaagggccggttcaccatcaccagagacaattccaacaacacgctgtttctgcaaatgaatagcctgagagccgaggacacggccatatattactgtgcgagagatattctgggagctactcggtttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11514 JY8QFUQ01CMSTH productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgtgtctgtggaactcag +11515 JY8QFUQ01B821R productive Homsap IGHV1-2*02 F 817 86.92 186/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame - tggatatactttcaccgaccattatgtttactggatgcgacaggcccctgganaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11516 JY8QFUQ01DLTIC unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 1 8 8 X 8.8.X [1.17.38.11] CAGYYPQVA#FDYW out-of-frame - ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattagcggtagtggtgatagcacatactacgcagactccctgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgggagccgaagacacggccgtatatcgctgtgcaggctattatccccaagtagcccctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11517 JY8QFUQ01CYWC2 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-7*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDRNYAFDYW in-frame + ctctggattcaccttcagcagctttagtatgaactgggtccgccaggctccagggaagggactggagtggctttcatacattagtaatactggtagtaacaaatactacgcagactctgtgaagggccgattcaccatctccagagacgatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgtgcgagagatcggaactacgctttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11518 JY8QFUQ01BT51R unproductive (see comment) Homsap IGHV3-9*01 F 1072 99.09 217/219 nt 98.63 216/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [2.17.38.11] CAKRLFRHIWKF#FDGW out-of-frame - stop codons in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); gcctctggattcacctttggtgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagtggtagcataggctatgcggactctgtgAaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagacctgaggacacggccttgtattactgtgcaaaaagactattcagacatatatggaaatttctttgacggctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11519 JY8QFUQ01C0U09 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11520 JY8QFUQ01A8IYT productive (see comment) Homsap IGHV3-30*01 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.37.11] CARGTMLRGVTKARYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 161 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11521 JY8QFUQ01A3UDN unproductive Homsap IGHV3-72*01 F 1093 98.67 222/225 nt Homsap IGHJ1*01 F 107 67.31 35/52 nt Homsap IGHD1-26*01 F 2 8 10 X 8.10.X [2.17.38.11] CLRPPRYDPW# out-of-frame - gcctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctgggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11522 JY8QFUQ01A03N6 productive (see comment) Homsap IGHV4-55*03 P (see comment) 734 82.03 178/217 nt 81.57 177/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 9 7 15 9.7.15 [1.17.38.11] CARDQSVYTAGSYFDSW in-frame + Potentially, because of detected insertion/deletion however the closest V is a pseudogene Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); tctctggtgactccatgagtagcgacacgtggtggagctgggtccgccagacgccagagaagggactggaatggattggggagatcaatcaaagagggacgacctcctacaacccgtccctcaggagtcgagtcgtcctgtcagtgggcgagtccaaaaaGtcaattctccctgaggctgacctctgtgaccgccgcggactcggccatctattattgtgcgagagatcagtctgtctatactgcgggaagttactttgactcctggggccagggaacgctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11523 JY8QFUQ01AJZDU productive Homsap IGHV3-66*02 F (see comment) 760 83.8 181/216 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-21*01 F 3 8 7 11 8.7.11 [2.17.38.11] CARHLMVYALDVW in-frame - Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaggggctggagtgggtctcagtcttatttagtactggcactgcatactacgcagactccgtgaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11524 JY8QFUQ01BV54S productive Homsap IGHV3-48*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDRGGSAYPIFDYW in-frame + cctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +11525 JY8QFUQ01B8I89 productive Homsap IGHV3-9*02 F 896 90.37 197/218 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame - cctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11526 JY8QFUQ01BKOVT productive (see comment) Homsap IGHV3-9*01 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggatttaactttgatcaatatgccatgtattGgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctgggtcaccgtctcgtcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11527 JY8QFUQ01BPTTW No results +11528 JY8QFUQ01AMAAI productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11529 JY8QFUQ01CJGIP unproductive Homsap IGHV3-7*02 F 895 90.74 196/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSAYFSTGY# out-of-frame - in FR2-IMGT at codon 42 of V-REGION: 'TCC' (3 nucleotides at position 39 to 41 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'GG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); tctagattcacctttaggacatattggatgaggttgggTCCcgcccaagctccagggaaaggGGgctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgagcagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactgggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11530 JY8QFUQ01BJ4OQ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11531 JY8QFUQ01CG70I unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 106 53.44 70/131 nt 8 8 X 8.8.X [1.17.9.X] null - No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +11532 JY8QFUQ01B8WTX unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11533 JY8QFUQ01BS4WZ unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [2.17.38.11] CARDNYGDYW# out-of-frame - in CDR2-IMGT at codon 62 of V-REGION: 'TG' (2 nucleotides at position 94 to 95 in the user submitted sequence), (cause frameshift); ctctggagttcagccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatTGgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactgggggccagggaacccctggtcacagtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11534 JY8QFUQ01C0PY0 unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11535 JY8QFUQ01ALIUD productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 932 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11536 JY8QFUQ01CT8AA productive Homsap IGHV3-11*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame + ctctggcttcaccttcagtgactactacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtggaagtggaactaccatatcctacggagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtatctccagatgaacagcctgagagccgaggacacggccgtatattactgtgtgaggcgggtgtggggatacagctatggttccgtctcgtactattttgagtactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtcagggcttcttccccc +11537 JY8QFUQ01AT0ML productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11538 JY8QFUQ01BM58O productive Homsap IGHV3-11*01 F 882 89.86 195/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVDIRLGDWFFDLW in-frame + ctctggattcatcttcagtgaccactacatgagctgggtccgccaggctccggggaagggtctggagtggatctcatacatcagtacaagtggtaatatggtttattacgcggactctgtgaagggccgattcaccgtctccagggacaacgccaagaactcactgtatctgcaaatgaacggcctcagagtcgaggacacggccgtctattactgtgtcgacataagactgggtgattggttcttcgatctctggggccgtggcaccctggtaactgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11539 JY8QFUQ01DSGY2 No results +11540 JY8QFUQ01AKSD0 No results +11541 JY8QFUQ01A1UEF unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*01 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDY#W out-of-frame + cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactacctgggggccaggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11542 JY8QFUQ01APSLB productive (see comment) Homsap IGHV3-48*01 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.16.38.11] CARASTFYYDGSGYRDVFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccaggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11543 JY8QFUQ01A3WOY No results +11544 JY8QFUQ01BUP6V unproductive Homsap IGHV3-74*03 F 909 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVDSDGWHGTIDR## out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaAaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggatagcgatggctggcacggaacaatagaccgctgggggccagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11545 JY8QFUQ01ALK8F productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); gttctggattcagtcctaccgatttttggatcggctgggttcgccagctgcccggCaaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc +11546 JY8QFUQ01BWQZE No results +11547 JY8QFUQ01APY1W No results +11548 JY8QFUQ01C7D8J productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 957 94.39 202/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD1-26*01 F 1 8 7 18 8.7.18 [1.17.38.11] CARGWAQQAGATFVGWFDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctatggtgggtccttcagtggttacacctggaactggatccgccagcccccagggaaggggctggagtggattggggaaatcaatcatagtggcaggaccaactacaacccgtccctcaagagtcgagtcaccatatcaatagacacgaccaacaaccagttctccctgaagttgacctctgtgaccgccgcggacacggctgtatatttctgtgcgagaggttgggcccaacaagcgggagctacgtttgttggctggttcgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttcccc +11549 JY8QFUQ01ALCY5 No results +11550 JY8QFUQ01B1XJ2 unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 981 94.93 206/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRDRYTDSWFNGNWF#PL out-of-frame + ctctggattcacatttgatgaatatggcatgagctgggtccgccaatctccagggaagaggctggagtgggtctctggtattaattggaatggtgccagcataggttatgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtttctgcaaatgaacagtctgagagccgaagacacggccttgtactactgtgtgagagacaggtataccgacagttggtttaatggaaactggttcgccccctgggccagggaacccaagtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +11551 JY8QFUQ01AY1B0 No results +11552 JY8QFUQ01AD6VN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11553 JY8QFUQ01CBR14 productive Homsap IGHV3-66*02 F, or Homsap IGHV3-66*03 F 863 89.3 192/215 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-25*01 F 1 8 7 11 8.7.11 [1.17.38.11] CARDGRGGDLDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tgtctgggttctccgtcagtttcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatctatgccgatggaagtacattctatgcagactccgtgaagggccgattcatcatctccagagacaattcaaagaacacgctcaatcttcaaatgaatagtttgagagttgacgacacggctgtgtattactgtgcgagagatgggcgcggcggtgaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11554 JY8QFUQ01BGVCA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11555 JY8QFUQ01CUNMM No results +11556 JY8QFUQ01DRT0U productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); cctctggattcagcttcagtacctataacatgaactgGggtccgccaggctccagGggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11557 JY8QFUQ01DGWHK unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11558 JY8QFUQ01CO9R6 productive Homsap IGHV3-11*01 F 910 90.87 199/219 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [2.17.38.11] CARVKYSSSWSSILDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcaacttcggtgactactacatgaactggatccgccaggctccagggaaggggctagagtgggtttcattcattagtagtcctggtatcaggagtttctacgcagactctgtgaagggccgattcactatttccagggacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgaggacacggccatatattactgtgcgagagtgaaatatagcagcagctggtcctcaatccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccccca +11559 JY8QFUQ01BY0OQ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 250 58.76 114/194 nt 58.25 113/194 nt 8 8 X 8.8.X [1.17.30.X] null - No rearrangement found Low V-REGION identity (58,76% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaCcctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11560 JY8QFUQ01CQ4VD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame - cgtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11561 JY8QFUQ01A24RC productive Homsap IGHV3-7*01 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11562 JY8QFUQ01CRIVN unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt 94.12 208/221 nt 10 7 X 10.7.X [2.16.38.X] null - No rearrangement found in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gtctctggtgactccatcagcagtagttcttactactgggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactgggccagcggggaaacccctggtcaccgtctccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccacc +11563 JY8QFUQ01APVPR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11564 JY8QFUQ01DEUV1 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 7 21 8.7.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 97 in the user submitted sequence), (cause frameshift) cctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11565 JY8QFUQ01BZJ86 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 856 88.13 193/219 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVSDRELHYQHLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11566 JY8QFUQ01BXHDN unproductive (see comment) Homsap IGHV3-7*01 F (see comment) 409 65.28 141/216 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt Homsap IGHD7-27*01 F 3 8 8 2 8.8.2 [1.17.38.6] NR*R in-frame + stop codons Low V-REGION identity (65,28% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaagcgtactatgcggactctgtgaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11567 JY8QFUQ01CVP8B productive (see comment) Homsap IGHV4-61*02 F 970 93.24 207/222 nt 92.34 205/222 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [2.16.38.11] CARGKWGDKPPFYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 73 in the user submitted sequence), (cause frameshift) tgtctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactgagtggattgggcgtatatatagcagtgggagcGatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11568 JY8QFUQ01BSWUK unproductive (see comment) Homsap IGHV4-39*02 F (see comment) 762 83.18 183/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CATIVPLFCDSTY*RSRKV#YFDHW out-of-frame - stop codons Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtgcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11569 JY8QFUQ01B5PZ4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11570 JY8QFUQ01B7WY5 No results +11571 JY8QFUQ01CZX79 unproductive Homsap IGHV3-48*02 F 828 87.1 189/217 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD5-18*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGDTVML#GMDVW out-of-frame + ctccggattcacctccatctcctatggcatgcactgggtccgccagattccaggaaaggggctggagtcggttgcatacattagtgatagtaatagcagcatatactatgcagactctgtgaagggccgattcaccatctcccgagacaaagacaagaagtcagtatatctgcaaatgagcagcctgagagacgaggacacggctatttattactgtgcgaggggcgatacagttatgctcacggaatggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11572 JY8QFUQ01DS9QD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-14*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CTKDYPDGRLLNHVFLFDH#W out-of-frame + ctctggattcacgtttgacgactatgccatgagttgggtccgccaggctccagggaaggggccggagtgggtctcaggtattattcctaatagtcgtgacagacactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagagcacagtgtatctgcaaatgaacaacctcagaggcgaggacacggccgtatattactgtacgaaagactatccggacggccgcctgctaaatcacgtcttcctttttgatcacttggggcgagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgtaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +11573 JY8QFUQ01BZEWU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame - Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11574 JY8QFUQ01BC7DJ productive Homsap IGHV1-18*01 F (see comment) 719 81.86 176/215 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD1-14*01 ORF 2 8 8 14 8.8.14 [0.17.38.11] CAREPEPRGAYGMDVW in-frame + Low V-REGION identity (81,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggttacgacttttccgcctatagtctcaattggatacgtcaggcccctggacacgggcttgagtgggtgggatggatcagtcgttctggtctccatatattctatgaacagagttttcagggcagagtcaccctgaccacagacacatccacgagcacagcctacatggagctgaggagcctgcaatctgacgacacggccatatattactgtgcgcgagaaccggagccccgaggggcctacggtatggacgtctggggcctagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11575 JY8QFUQ01B7JLL No results +11576 JY8QFUQ01A1WCP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 892 89.95 197/219 nt 89.04 195/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [2.17.38.11] CSKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gcctctggattctccgtcagtaAgttactggatgcactgggtccgccaggctccagGgggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11577 JY8QFUQ01C1OW3 unproductive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSSPYFYDSNGY## out-of-frame + cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +11578 JY8QFUQ01CB60R productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactc +11579 JY8QFUQ01C37BK unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD2-15*01 F 3 7 8 X 7.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift) ctccggattcaccttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctctcagatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11580 JY8QFUQ01DNLB6 unproductive (see comment) Homsap IGHV4-55*07 P (see comment) 689 79.72 173/217 nt 78.34 170/217 nt Homsap IGHJ6*04 F 90 60.32 38/63 nt Homsap IGHD3-3*02 F 1 9 7 X 9.7.X [1.17.38.11] CARHVRGILQEGHFCSASACHSFDSW# out-of-frame - however the closest V is a pseudogene Low V-REGION identity (79,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 42 of V-REGION: 'GGGAT' (5 nucleotides at position 44 to 48 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'CT' (2 nucleotides at position 81 to 82 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 131 to 131 in the user submitted sequence), (cause frameshift); tgtctggtgactccatctccagggattatgcgttactgggggtGGGATccgccagtccccagggaagggactggagtggaCTttgggggcgtctctcatgatgggatcaccttctacaccccgtccctcaCgggggcgagtcaccatctccgtggacgggtccaagaaccacttctccctgaggctggactccacgaccgccgcagacacggctatttattactgtgcgagacatgtccgtgggattcttcaggagggacatttctgtagtgcttctgcttgccactccttcgactcctgggggccagggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11581 JY8QFUQ01C4V7J No results +11582 JY8QFUQ01BC8PD productive Homsap IGHV1-24*01 F 988 96.24 205/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame - ggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11583 JY8QFUQ01ABFPI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccttgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11584 JY8QFUQ01BEU2A productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagatacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactc +11585 JY8QFUQ01A6DLE productive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARCPNYNIGTRGFDYW in-frame - tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11586 JY8QFUQ01ADGIJ No results +11587 JY8QFUQ01CI99L unproductive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSGFLLDG#YW out-of-frame - ctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtgggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11588 JY8QFUQ01CJG1W productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-3*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDGVRGLGAYYIYYFDSW in-frame + ctctggattcacctttggcctctatgccatgaactgggtccgccagactccagggaaggggccggagtggctcgcaactatcagtggtagtggaagtaggtcattctacgcagactccctcaggggccgtttcaccatctccagagacaattccaagggcacggtgtacctggacatgaccaccctgggagccgacgactcggccgtgtattactgtgccagagatggagtccgtggccttggtgcttattatatctactattttgactcatggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcc +11589 JY8QFUQ01C91CR unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); gcctcaggattcaccttcagtaggtactggatgcactGgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11590 JY8QFUQ01BGO73 No results +11591 JY8QFUQ01AXVIZ unknown (see comment) Homsap IGHV3-74*03 F 135 55.56 75/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11592 JY8QFUQ01BWOJ4 No results +11593 JY8QFUQ01DHLHH No results +11594 JY8QFUQ01B639Y productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1090 100.0 219/219 nt 99.09 217/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 3 8 10 12 8.10.12 [X.17.38.11] CTKCSVTIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'A' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ggattcaccAtttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgAaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11595 JY8QFUQ01AJVHR productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +11596 JY8QFUQ01BG2KZ productive Homsap IGHV3-7*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame + cctctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgctggtcccaggggcttcttccccc +11597 JY8QFUQ01DWQZH No results +11598 JY8QFUQ01CMLMU unproductive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 X 9.7.X [1.17.38.11] CARGETDC##YYFDYW out-of-frame + stop codons tctctggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaactgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11599 JY8QFUQ01A1364 productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtatattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11600 JY8QFUQ01BG2XI No results +11601 JY8QFUQ01AX1NQ No results +11602 JY8QFUQ01DITE7 productive (see comment) Homsap IGHV3-48*02 F 945 93.09 202/217 nt 92.17 200/217 nt Homsap IGHJ6*02 F (see comment) 238 87.1 54/62 nt Homsap IGHD4-11*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CARADYRNYYAGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); ctcaggattcaccttcagtacctatagcatgaactgGggtccgccaggctccagGggaaggggctggagtggatttcatacattagcgctactagtactaccatatattacggagactctatgaggggccgattcaccatctccagagacaatgccaagaactcactttatctgcaaatgaatagcctgagagacgacgacacggctgtgtattactgtgcgagagccgactacaggaactactacgccggtatggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc +11603 JY8QFUQ01C58E8 No results +11604 JY8QFUQ01C09Y9 No results +11605 JY8QFUQ01DPX57 unproductive Homsap IGHV3-48*01 F 1085 100.0 218/218 nt Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CASRLRSSGGY## out-of-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaacccgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11606 JY8QFUQ01C4N11 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtc +11607 JY8QFUQ01A8WCU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1085 100.0 218/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKDRITIFSYNWFDPW in-frame - cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +11608 JY8QFUQ01CUTH2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11609 JY8QFUQ01BHY5R productive Homsap IGHV3-11*01 F (see comment) 963 94.01 204/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] YARRRDYGDYGDGFDYW in-frame + Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactatgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcaatgcctggtccagggcttcttccc +11610 JY8QFUQ01DK9JD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggttaaggactacttccccgaaccggtgacggtgtcgtggaactc +11611 JY8QFUQ01BTDKT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgtctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccacaagggcccatcggtctcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11612 JY8QFUQ01DWVME productive (see comment) Homsap IGHV3-21*04 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 7 8 16 7.8.16 [2.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) gcctctggattcagtttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11613 JY8QFUQ01B7U7C productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11614 JY8QFUQ01AL6EV productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDYFDSW in-frame - tggatacaccttcaccgactacttcatacactggctgcgacaggcccctggacaacgacttgagtggatgggatggatcaaccctaagaatggtgacacaaagtatgcacagaactttcagggccgggtcaccatgaccagggacacgtccgtcagcaccatatatgtggaggtgagcagcctggaatctgacgacgcagccacttattactgtgcgagaggcttttatggtgactactttgactcctggggccagggagccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11615 JY8QFUQ01A8RKJ productive (see comment) Homsap IGHV3-7*01 F 949 93.52 202/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.16.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) cctctacattcacgtttagtcggtattggatgagctggtccgccaggctccagggaagggcctggagtggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11616 JY8QFUQ01DS6BY No results +11617 JY8QFUQ01ABI4U productive (see comment) Homsap IGHV4-39*03 F 928 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 9 7 17 9.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) ctccggtggctccatcaacagtagaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11618 JY8QFUQ01C5KM1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + tctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11619 JY8QFUQ01CZMGC productive (see comment) Homsap IGHV3-48*01 F 1085 100.0 218/218 nt 99.08 216/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11620 JY8QFUQ01A2F1Z unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11621 JY8QFUQ01CNWIQ productive Homsap IGHV3-48*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTRQTGNYYYFGVDVW in-frame + ctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11622 JY8QFUQ01AHX1B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKLGVAATTWNFFDYW in-frame + ctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11623 JY8QFUQ01DU62D productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 1016 97.21 209/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-18*01 F 3 8 7 15 8.7.15 [1.17.38.11] CARGPGRGYSYGYLYYW in-frame - tctatggtgggtccttcagtggttactactggaactggatccggccagccccagggaaggggctggagtggattggggaaatcaatcatagtggaagcaccaactacaacccgtccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcggacacggctgtgtattactgtgcgagaggcccggggcgtggatacagctatggttacttatactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11624 JY8QFUQ01CBX8Y unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 99 52.59 71/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11625 JY8QFUQ01BQVJM unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found tgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag +11626 JY8QFUQ01CX6W8 No results +11627 JY8QFUQ01BTUG9 productive Homsap IGHV3-48*01 F 1075 100.0 216/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11628 JY8QFUQ01C6PSP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11629 JY8QFUQ01DNSKU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagtagcGtatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11630 JY8QFUQ01BW865 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 872 89.77 193/215 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - caggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgcttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaagtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11631 JY8QFUQ01B41FE productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11632 JY8QFUQ01BEE11 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 898 89.64 199/222 nt 89.19 198/222 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-3*01 F 2 10 7 18 10.7.18 [2.17.38.11] CARSQRSAWSGQPRNWFETW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 31 of V-REGION: 'A' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); tctgctggtggctccatcaAgcagtaacccttattactggggctggatccgccagcccccatggggggggctggagtgggttggcagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgaatcaccatgtccgtggacacgtccaggacccagttctccctgaagttgagctctgtgaccgcctcagatacggctgtgtattattgtgcgaggtcccaaaggagtgcttggagtggacagcctagaaactggttcgagacctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11633 JY8QFUQ01AEYTS productive Homsap IGHV3-7*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtctgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11634 JY8QFUQ01BTFS8 unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-23*01 ORF 3 8 7 X 8.7.X [1.17.38.11] CARGDGVKDDY## out-of-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccaggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +11635 JY8QFUQ01ACKK7 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 891 90.32 196/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift) cctctggatcaccctttggttattGatggcatgactgggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11636 JY8QFUQ01ASCWW No results +11637 JY8QFUQ01AMDQC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAIEHTLPSGQGLGIEYFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cagcctctggattcaactttaacagctttgccatgagctgggtccgccaggttccagggatggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactccgtgAaagggccggttcaccatctccagagacaactccaacaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgatcgagcatacccttccgtccggacagggattagggattgaatatttctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11638 JY8QFUQ01CNRIE unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 946 92.69 203/219 nt 91.32 200/219 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [2.16.38.11] CARPAFSGSGTYRP#DGFDVW out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ggtttctggatacagcCtttaccaattactggatcggctgggtgcgccaggtgcccggaaaagcctggagtggatCggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcagtaccgcctaccttcagtggagcagtctagcgacctcggacaccgccatgtattactgtgcgagaccagctttctctggttcggggacttaccggccgaggatggttttgatgtctggggccaaggaacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11639 JY8QFUQ01ACBLB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 797 85.32 186/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKVWIELWSAGDHFDNW in-frame + cctctggattcatatttactagatatgccatgacctgggtccgccaggctccagggaagggtctggagtgggtcgcttctatcagtggtagtgggattagtaaaaagtacgcagacggcgtggagggccgattcaccatctccagagacagttccgagagaacactgtatctacaaatgaacagcctgagagtcgaggacacggccacatattattgtgcgaaagtatggatagagttatggtcggctggggaccactttgacaactggggccagggaaccctggtcaacgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11640 JY8QFUQ01CG8EF No results +11641 JY8QFUQ01CADUW productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); ctctggattcaTcgttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaataCcgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +11642 JY8QFUQ01APLX8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 3 8 8 10 8.8.10 [1.17.38.11] CASFRVLESGYW in-frame + ctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11643 JY8QFUQ01A6CF8 No results +11644 JY8QFUQ01BBSCF productive (see comment) Homsap IGHV4-61*02 F 897 90.0 198/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.16.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) tctccggtggctccatcagtactggttattactactGggagctggatccggcagtccgccgggaagggactgaatggattgggcgcatgtctgccagagggggAcagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11645 JY8QFUQ01CWUX1 unproductive Homsap IGHV3-21*04 F 990 95.39 207/217 nt Homsap IGHJ5*01 F 84 62.75 32/51 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARAVSNQVDV## out-of-frame - ctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctgggggccaagggaccacggtcaccgtctctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11646 JY8QFUQ01DGWJE No results +11647 JY8QFUQ01DBVMQ productive (see comment) Homsap IGHV4-61*02 F 888 89.55 197/220 nt 89.09 196/220 nt Homsap IGHJ4*01 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-22*01 F 3 10 7 11 10.7.11 [1.17.37.11] CARAREFLTFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 87 of V-REGION: 1 nucleotides (from position 170 in the user submitted sequence), (cause frameshift) tctctggtgcctccatcaacaatgatactttctactggaactggatccggcaggccgccgggaagggactgcagtggattgggcgtatgtatgccagtgggaccactaactacaacccctccctcaagagtcgagtcaccatgtcagtagtcacgtcaaagaatcaatttccctgaagttgagttctgtgaccgccgcagacacggccatttactactgtgcgagggcccgagagtttctcacctttgactcctggggccaaggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11648 JY8QFUQ01BURQO No results +11649 JY8QFUQ01BDDGB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD2-21*02 F 3 8 8 20 8.8.20 [1.17.38.11] CAKEGDGSVIPSPVPEWKFDSW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttgacagccatgccatgcactgggtccgtcgggctccagggaaggggctggagtgggtctcggcagttagtggtggtggccattatacatactacgcgcgctccgtgaagggccgatttaccatatccagggacaattcccgaaacatggtgtatttggagatgactggcctgacagccgaggacacggccgtatattattgtgcgaaagagggagacggatcagtgatcccgtctcctgttcctgagtggaaatttgactcctggggccagggaaccctggccacggtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +11650 JY8QFUQ01DO4D1 No results +11651 JY8QFUQ01CDQ0Y productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + tctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11652 JY8QFUQ01AW8OZ productive (see comment) Homsap IGHV4-39*02 F 942 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [1.16.38.11] CARRYSWNYERFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtactaataattactactgggcctggatccgccagccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11653 JY8QFUQ01B9FHT No results +11654 JY8QFUQ01DI8JM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 950 83.15 227/273 nt 82.78 226/273 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [20.17.38.11] CVRYDYSRLHRSNYFGPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,15% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); ggggggcgccatcagacgantgcgtctggggagtctctgaagatctcctgtgcagtctctggattcaccttcatcagttatggcatgagttgggtccgccaggTttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11655 JY8QFUQ01ARK8Q No results +11656 JY8QFUQ01BTIAT productive Homsap IGHV3-9*01 F 922 92.13 199/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + tctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +11657 JY8QFUQ01CAR33 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKEEGATGVYYVDH# out-of-frame - gcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactgggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11658 JY8QFUQ01A1JGU No results +11659 JY8QFUQ01C9XIH No results +11660 JY8QFUQ01CQDC1 unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 985 93.33 210/225 nt 92.89 209/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 9 9 X 9.9.X [1.17.38.11] CARGVIIMIVVV#DYW out-of-frame - in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 33 in the user submitted sequence), (cause frameshift) tctcggggacagtgtctctagcagcagtgttgttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagaggggtgattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +11661 JY8QFUQ01B27PW productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11662 JY8QFUQ01ASWW4 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 885 90.65 194/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 X 8.7.X [1.17.38.11] CAKTTMTSVT#DWFDPW out-of-frame + ctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactgggggcaccgactccaacccctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagacccagccagatgggaacgtgtcatcgcctgcctggtccagggcttcttccccca +11663 JY8QFUQ01BD9FJ No results +11664 JY8QFUQ01CV6RU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDVSTRITMRVVVPALDYW in-frame + gtctggattcacgtttagaaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattagtgataatggtgacagcatattccacgcagactccgtgaagggccggttcaccatcaccagagacaactctaagaacatcctgtatctgcacatgaacagcctgagagccgaggactcggccgtatattactgtgcgaaggatgtttccacgcgtattactatgagagttgtggtgccagcccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +11665 JY8QFUQ01CRLC9 productive Homsap IGHV3-9*01 F 901 90.41 198/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [2.17.38.11] CVRQAYYHDSSAYFFSRYWYFDLW in-frame - gcctctggattcacttttgatgactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacgccaagaagtccctgtttctgcaaattaaaagtctgagagttgaggacacggccttatattattgtgtgaggcaagcgtattaccatgatagcagtgcttacttcttctcccgctactggtacttcgatctctggggccgtggcaccccggtcactgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11666 JY8QFUQ01DIGF6 unknown (see comment) Homsap IGHV4-31*06 F, or Homsap IGHV4-61*01 F or Homsap IGHV4-61*03 F or Homsap IGHV4-61*04 F 127 57.27 63/110 nt 10 7 X 10.7.X [1.17.1.X] null + No rearrangement found tctctggtgcctccgtcagcagtggtagtttctactggacctggattcgtcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11667 JY8QFUQ01C6628 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 930 92.99 199/214 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDPSYSYYNGLDVW in-frame - stop codons tggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtaggtctcaactattagtggtagtggtggtaggacatactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcatgcctggtccagggcttcttccccca +11668 JY8QFUQ01DR5VR productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 639 77.42 168/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [0.17.38.11] CVRHVRRFWFDPW in-frame - Low V-REGION identity (77,42% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggtttcacggttcagtggctctgctatgcactgggtccgccaggcttccgggaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11669 JY8QFUQ01C9VQE unproductive Homsap IGHV3-7*03 F (see comment) 374 82.73 91/110 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD4-11*01 ORF 3 X X X X.X.X [X.X.36.11] CARDRYSSDSSYYMPNWLD#PG out-of-frame + Low V-REGION identity (82,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacgtttgggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11670 JY8QFUQ01DGPFY productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +11671 JY8QFUQ01C29UK No results +11672 JY8QFUQ01DE1JB productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'G' (1 nucleotides at position 137 to 137 in the user submitted sequence), (cause frameshift); tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtgGgattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccaGtttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11673 JY8QFUQ01CTI5L No results +11674 JY8QFUQ01B9H6N No results +11675 JY8QFUQ01AL0PM unproductive Homsap IGHV3-48*02 F 976 94.91 205/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGEGDPFF##YYSGLDVW out-of-frame - tctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11676 JY8QFUQ01BK32N unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 705 91.07 153/168 nt 8 7 X 8.7.X [1.17.22.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BK32N ; 8 AA in Homsap_IGHV3-11*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatct +11677 JY8QFUQ01BHITL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame - Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11678 JY8QFUQ01BMWB9 No results +11679 JY8QFUQ01B6AL4 No results +11680 JY8QFUQ01BXKFJ unknown (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 810 86.18 187/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11681 JY8QFUQ01C2B2K unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag +11682 JY8QFUQ01DUWZ2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccgaccaagggcccatcggtcttccccctggcaccctcctccaagagcagcctctgggggccacagcggccctggggcctcctggtcaagggactacttccccggaaccggtgacggtgtcgtggaactcag +11683 JY8QFUQ01CE6CM unproductive Homsap IGHV3-30*01 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGVTKARYGLDV## out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggGggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctgggggccaagggaccacggtcatcgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11684 JY8QFUQ01APBW6 productive Homsap IGHV3-13*01 F 976 94.91 205/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame - gcctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11685 JY8QFUQ01A7QSW productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD5-12*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARDGSAHSSIYHYYYGMDVW in-frame - cctctggattcaccttcagttctcacactatgaactgggtccggcaggctccagggaaggggccggagtgggtctcaaccattggtactagaggtagatccatatactacgcggactcagtgaagggccgattcaccacctccagagacaacgccaagaaatcactttatctggatatgcacagcctgagagccgaggacacggctatctattactgtgcgagagatggcagtgcacactcgtcgatctatcattactattacggcatggacgtctggggccaagggaccacggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11686 JY8QFUQ01BQQSG No results +11687 JY8QFUQ01ARTMQ No results +11688 JY8QFUQ01DQZSS productive Homsap IGHV3-66*02 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame + ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagcgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11689 JY8QFUQ01BXJ63 productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +11690 JY8QFUQ01CBV9T productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11691 JY8QFUQ01ADHL2 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11692 JY8QFUQ01CNKAD unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARLGQLALDY## out-of-frame + gttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactgggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccttggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +11693 JY8QFUQ01BCBWP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11694 JY8QFUQ01DCDKD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 779 84.4 184/218 nt 83.94 183/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); gtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGgggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11695 JY8QFUQ01BUIGH unproductive Homsap IGHV3-9*02 F 901 90.41 198/219 nt Homsap IGHJ6*02 F (see comment) 96 63.16 36/57 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [2.17.38.11] CGKDMRPGGMDV## out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctgggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11696 JY8QFUQ01CGD1Q productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 82.79 178/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [2.16.38.11] CARGTRYNNGLDAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 151 to 151 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) gtctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactgagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtCccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11697 JY8QFUQ01ARSIX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame + ctctggattctccgtcagtaattactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11698 JY8QFUQ01DOVDS unproductive Homsap IGHV3-74*03 F (see comment) 697 80.56 174/216 nt Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRGTTGWRGVDY## out-of-frame - Low V-REGION identity (80,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcaacgtcagtggatactggatgcactgggtccgccaagtgccagggaaggggctggtatgggtctctaggctttcggatgatgaaattactataacttacgcggactttgtggagggccgattcaccatctccagagacaacgccaggaacgaggtctatctgcaaatgaatgatttgagagtcgacgatacggctgtatacttttgtgtgaggggaaccactggctggaggggggttgactactgggggccaaggcgccctcgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11699 JY8QFUQ01AN2WD productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.16.38.11] CARAPRTATLLDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccaagaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11700 JY8QFUQ01BNGHT No results +11701 JY8QFUQ01C50HS productive Homsap IGHV4-61*02 F (see comment) 569 73.3 162/221 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARECSNSKVGPRALDSW in-frame + Low V-REGION identity (73,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) tttctggtggcccgatcaaaagtcctgattaccattggacgtggatccggcaggccgccgggaaggggctggagtgggtcgggcgtgtctatatgactggctatgtcgagaacaatccatccctctccgggcgtctctccatgtcgattgacacggcgaagaatcagttttctatgacattgacttctgtgaccgccgcagacacggccctttatttttgtgcgagggagtgtagtaattcgaaagtcggaccgagagcgcttgactcctggggcccgggaagtctggtcaccgtatcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11702 JY8QFUQ01AF4BD productive Homsap IGHV3-9*01 F 815 86.24 188/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD5-24*01 ORF 3 8 8 17 8.8.17 [1.17.38.11] CVKDRKAGGYNLLDAFDIW in-frame + cctctggattcaccttcgacgactatgtcatgcattgggtccggcaagttccagagaggggcctggagtgggtcgcaggcattaatggggaaagtaatagttttggctctgtggactctgtaaagggccgattcaccatctccagagacaaggccaagaataccctgtatttgcaaatgaatagcctgagagttgaggacacggccttgtattattgtgtgaaagatagaaaagctggtggctacaatctgttggatgcttttgatatctggggccaagggacaatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11703 JY8QFUQ01CQN1T productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccagtgacggtgtcgtggaactcag +11704 JY8QFUQ01AKSJT productive Homsap IGHV3-21*04 F 995 95.41 208/218 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 163 76.79 43/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame + cctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +11705 JY8QFUQ01CBA4N unknown (see comment) Homsap IGHV3-72*01 F 106 53.44 70/131 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +11706 JY8QFUQ01A36I7 unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDY* in-frame + stop codons ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactgaggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca +11707 JY8QFUQ01CNKXB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 830 86.43 191/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [2.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame - tagcctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11708 JY8QFUQ01BSREQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11709 JY8QFUQ01CXM27 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 7 8 10 7.8.10 [1.17.38.11] CAREVSDALDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) ctctggattcatctttgatgatttggcatgagatgggtccgccaagttccagggaaggggccacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11710 JY8QFUQ01DK61J productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11711 JY8QFUQ01AWBO4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 802 85.39 187/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*02 F 3 8 8 9 8.8.9 [2.17.38.11] CARGDVIGDCW in-frame - cctcggattgcaacttgcagagactactggatgcactgggtccgccaagctccagggaaggggctgacgtgggtctcacgtatttatggtgatgggggtaacacagcctatgcggactccgtgaagggccgattcaccatgtccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagacccgacgacacggctatatattattgtgcaaggggcgatgttatcggagactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11712 JY8QFUQ01A96Y3 No results +11713 JY8QFUQ01CPO10 productive Homsap IGHV3-7*01 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11714 JY8QFUQ01ATPO0 No results +11715 JY8QFUQ01C8GVB productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*06 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 823 87.04 188/216 nt 86.57 187/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [1.17.38.11] CARGDGYNFGGLDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 83 of V-REGION: 'T' (1 nucleotides at position 153 to 153 in the user submitted sequence), (cause frameshift); tctggattcaacttcataggttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactccgtgaggggccgatccatcatttccagagacgattcTaaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11716 JY8QFUQ01CCJBJ unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11717 JY8QFUQ01BO6AT productive Homsap IGHV3-7*01 F 1026 97.24 211/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame + ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +11718 JY8QFUQ01DEL2A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11719 JY8QFUQ01AZ6CA No results +11720 JY8QFUQ01C1RGN productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11721 JY8QFUQ01DH08T productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 908 91.63 197/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - cctctgggttcaccgtcagtagcaagttcatgagctgggtccgccagggtccagggaaggggctggagtgggtctcagttacttatcctgatggtactacacattatagagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11722 JY8QFUQ01CMH6G No results +11723 JY8QFUQ01BE0DI productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1028 96.38 213/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [2.17.38.11] CILLYYDSRGVFSTDYW in-frame - cagcctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggcgtgggtctcacgtattaaaagtgatggcagtggcacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagagcacgctgtttctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtatactgctttactatgatagtagaggtgtcttttcaaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11724 JY8QFUQ01ANFJ6 productive (see comment) Homsap IGHV4-59*03 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [2.17.38.11] CARGHFDSSGYSNPLDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 91 to 96 in the user submitted sequence), (do not cause frameshift); gtctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccctcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11725 JY8QFUQ01DP62P No results +11726 JY8QFUQ01BTSZG unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD5-24*01 ORF 1 8 7 9 8.7.9 [4.17.38.11] CARGAPFS**C in-frame + stop codons ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11727 JY8QFUQ01CHSPD No results +11728 JY8QFUQ01CZ8TU productive Homsap IGHV3-48*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGNYYYFGMDVW in-frame + ctctggattcctcttcagtagctttaacatgaactgggtccgccaggttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccatctactactgtgcgagacaaactgggaattattattacttcggtatggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccccca +11729 JY8QFUQ01DI3WD productive Homsap IGHV4-61*02 F 816 85.91 189/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 10 7 18 10.7.18 [1.17.38.11] CAREDYYGSGSYGRAWFDSW in-frame + ctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtgggggtgtcgactacaacccctccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagaggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +11730 JY8QFUQ01CTRR1 productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.38.11] CSRLLEEW in-frame + cctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc +11731 JY8QFUQ01B5ZOX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11732 JY8QFUQ01CA78F No results +11733 JY8QFUQ01AGZN5 productive Homsap IGHV3-53*04 F 787 85.19 184/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 8 7 12 8.7.12 [2.17.38.11] CARQTAPLGTLTYG in-frame - tctcgggggttcaccgtccaaaacagcttcatgagttgggtccgccaggctccagggaagggcctagagtgggtctcagttgtttatagtggtggatccacatactacgcagactccgtgaagggccgtttcaccatcgccagacacagtcgcaacaacattctgtatcttcaaatgaacagcctgagacctgaggacacggctgtttacttctgtgcgagacagactgcccctttgggaactttgacttatgggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11734 JY8QFUQ01CX7WS No results +11735 JY8QFUQ01C2OUK productive (see comment) Homsap IGHV3-7*01 F 960 93.18 205/220 nt 92.27 203/220 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 6 8.8.6 [2.17.38.11] CVKSIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'AT' (2 nucleotides at position 17 to 18 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); agcctctggattcagcATtttagcagctTtttggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagtgggatggaagtgataaaaagtatatggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactatatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtgaaaagcattgactcctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagtcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +11736 JY8QFUQ01BTTRX productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CAREKGSGPPTGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11737 JY8QFUQ01AJ8IZ productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 7 13 8.7.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccgtcggtagcaactacatgacctgggtccgccaggctccagggaaggggctggagtggctctcagttatttacagcggtggtagtaaatactacgcagactccgtgaagggccgattcaccatctccagagacagttccaagaacacgctgtttcttcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11738 JY8QFUQ01B335M productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +11739 JY8QFUQ01C6JWV unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1004 95.87 209/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CVRGDYGGAPDITTT#YGLDVW out-of-frame - cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11740 JY8QFUQ01AL74E productive Homsap IGHV3-48*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGNYYYFGMDVW in-frame - tctggatttcctcttcagtagctttaacatgaactgggtccgccaggttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagaggcaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccatctactactgtgcgagacaaactgggaattattattacttcggtatggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +11741 JY8QFUQ01CMVYS No results +11742 JY8QFUQ01AU098 unproductive Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDGPPYLYGSHGNSFDQ## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggcccagggaaccctagtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11743 JY8QFUQ01BE6AZ No results +11744 JY8QFUQ01DSIIG productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); ttctggatacacatttatgaattattggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagccCcgtcctttcaaggccaggtcaccatttcagccgacaagtccaccaacaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggccctatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11745 JY8QFUQ01DOMCB No results +11746 JY8QFUQ01B5SA1 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +11747 JY8QFUQ01ABG7J productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 704 80.09 177/221 nt 79.64 176/221 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 169 82.0 41/50 nt Homsap IGHD4-17*01 F 2 8 8 16 8.8.16 [3.16.38.11] CAKDRLNGDYTFGAFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 63 in the user submitted sequence), (cause frameshift) agcctcctaaatttgacgttcaggacatatggcatgaactgggtccgccaggttccagggaagggctggagtgggtctcctacataagtcgtctgagtcgccaaatatatgtcgctgacccagtgaagggccgattcaacatctccagagacaacgccaagaattcactgtatctgcaaatgaacaacttgcgggtcgaagacacggctgtgtatttttgtgccaaagatcgcctgaacggtgactacacattcggcgcatttgatctgtggggcccagggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11748 JY8QFUQ01AYTLP productive (see comment) Homsap IGHV3-7*01 F (see comment) 742 82.87 179/216 nt 81.94 177/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaatacgaaatattttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11749 JY8QFUQ01CACC0 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.17.38.11] CARGEMTAEYYFDYW in-frame + ctctggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11750 JY8QFUQ01B617C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 926 92.56 199/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARFGPLTRPDYW in-frame + ctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11751 JY8QFUQ01C42O1 productive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11752 JY8QFUQ01C4BEQ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 888 89.55 197/220 nt 88.64 195/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); ctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagccCcccagagaagggtctggagtacattgggaAgcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +11753 JY8QFUQ01BES25 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 866 88.24 195/221 nt 87.78 194/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARQLSGDYASFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaccagtggtaCttttttactgggcctggatccgccagcccccagggaaggggctggagtgggttggcaatatctattctagtggtgtcgcctattacaacccgtccctcaagagtcgagtcaccatgtccgtcgacacgtccaagaatgagttttccctgacactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11754 JY8QFUQ01B8P9X No results +11755 JY8QFUQ01CFJVQ No results +11756 JY8QFUQ01CMD6N No results +11757 JY8QFUQ01BFNWB productive (see comment) Homsap IGHV4-4*07 F 813 86.92 186/214 nt 86.45 185/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgCaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11758 JY8QFUQ01BX39A productive (see comment) Homsap IGHV3-7*01 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRDRPGGWALDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); ctctggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaTggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11759 JY8QFUQ01BQVI7 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1030 97.69 211/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGPHQYY#DYW out-of-frame - tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11760 JY8QFUQ01BVW4H No results +11761 JY8QFUQ01CGRWZ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11762 JY8QFUQ01CA6E6 No results +11763 JY8QFUQ01A1IV8 productive (see comment) Homsap IGHV4-4*07 F 849 88.79 190/214 nt 87.85 188/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 7 11 8.7.11 [1.17.37.11] CARSGWDNQFDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'TGGCAC' (6 nucleotides at position 23 to 28 in the user submitted sequence), (do not cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) tctctggtgtcgccaccagtagTGGCACttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaaccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11764 JY8QFUQ01COQVB productive Homsap IGHV3-9*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKDRGSSSKYYFDYW in-frame - cctctggattcacctttgatgattatgtcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggggaagtgctcatatacactatgcggactctgtgaaggaccggttcaccatctccagagacaacgccatgaactccctttatttgcaaatggacagtctgagagctgacgactcggccttgtattactgtgtaaaagatcggggtagcagttccaagtattactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11765 JY8QFUQ01BSQ74 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11766 JY8QFUQ01BS5PY unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CAREVIPTATYGMDL## out-of-frame + in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); tctggattcacgtttagtagAttttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctgggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11767 JY8QFUQ01BAP9G unknown (see comment) Homsap IGHV3-23*02 F, or Homsap IGHV3-23*03 F or Homsap IGHV3-30*05 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*12 F 137 52.72 97/184 nt 8 7 X 8.7.X [0.17.28.X] null - No rearrangement found ctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11768 JY8QFUQ01AOU7X productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11769 JY8QFUQ01AGDVH productive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame + ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11770 JY8QFUQ01BDXYZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 886 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'TG' (2 nucleotides at position 36 to 37 in the user submitted sequence), (cause frameshift); ctctgggttcacctttagcagctatgccatgacgtTGgggtccgccaggctccagggaaggggctggagtgggtcncaagtatcagttttagtggtgagagaacatattatgcagactccgtgaagggccggtacaccatctccagagacaattccaagaatacgatgtctgtgcaaatgagcagcctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +11771 JY8QFUQ01AD0SF No results +11772 JY8QFUQ01CCD99 productive (see comment) Homsap IGHV3-7*01 F 890 90.7 195/215 nt 89.77 193/215 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-2*01 F 3 8 7 19 8.7.19 [1.17.38.11] CVRDGGVIVVVPMDYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 66 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 2 nucleotides (from position 83 in the user submitted sequence), (cause frameshift) ctctggtttcacatttagtacgtactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacatagcgagatggaactgagaggtCattatgtggactctgtgaagggccgattcatcatctccagagacaactccaggaatttactgtatctccaaatgaacagcctgagagtcgaagacacggctgtgtattattgtgtgagagatgggggtgttattgtagtagtgccaatggactattacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11773 JY8QFUQ01BCUZS unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ2*01 F 112 67.92 36/53 nt Homsap IGHD2-21*01 F 2 8 8 X 8.8.X [1.16.38.11] CAKVVWSL##YFDLW out-of-frame - in FR3-IMGT at codon 104 of V-REGION: 'C' (1 nucleotides at position 217 to 217 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgCtgcgaaagtagtctggagcctctgggtacttcgatctctggggccgtggcaccctggctcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11774 JY8QFUQ01DM4XQ No results +11775 JY8QFUQ01ABYQ3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 693 80.18 174/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGLGLNAVYAFDVW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcgcttttggagattatgccatgaactgggtccgccaggccccagggaagggactggagtgggtctcaggtttgagcggtagaggcgtcagcaaatattatgcagactccgtgaggggccggttctccatttccagagacaactccgggagcgaggcagtccttcaaatgagcagcctgagagtcgaggacacggccacttactactgtgcgaggggcctagggcttaatgctgtctacgcatttgacgtctggggacaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11776 JY8QFUQ01AVMP9 No results +11777 JY8QFUQ01CITZL productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGDYYDSGGLDYW in-frame + tccggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtgattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +11778 JY8QFUQ01CA0LL productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 894 91.12 195/214 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame + ttctgggttcaccgtcagtagcaagttcatgagctgggtccaccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcctcagcatccccgaccagccccaaggttcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +11779 JY8QFUQ01C529M productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARDGEWEMLDHW in-frame + ctccggattcaccttcagtaggtattggatgtattgggtccgccaagctccaggcaaggggctggtgtgggtctcacgcattaaaagtgatgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacatatttttgtgcaagagacggggagtgggagatgcttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +11780 JY8QFUQ01CR1J3 No results +11781 JY8QFUQ01BZBRJ No results +11782 JY8QFUQ01B2IY9 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11783 JY8QFUQ01CNK6J productive (see comment) Homsap IGHV4-39*02 F 834 86.36 190/220 nt 85.91 189/220 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD2-15*01 F 1 10 7 11 10.7.11 [1.16.38.11] CARMLLRRDFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtagtatctactactggggctggatccgccagcccccaggaaagggctagaatggatcggaagtatcaactccattgggaccacctatcacaacccgtccctcaagagtcgagtcgccatgtccgttgatccgtccatgaggcacttctccctgaaagttagctctgtgaccgccgcagacacggctgtctattactgcgcgagaatgttgcttcgccgcgatttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgttgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11784 JY8QFUQ01DKALV unproductive Homsap IGHV3-7*01 F 873 89.4 194/217 nt Homsap IGHJ1*01 F (see comment) 116 69.23 36/52 nt Homsap IGHD3-16*01 F 1 8 8 X 8.8.X [1.17.38.11] CARATNADV# out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcacctttagggggtactggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaccataaatcacgatggaagtcaaatttactatatggaccttgtgaagggccggttcaccatctccagagacaacgccgagacctcactctatttgcaaatgaacaccctgagagccgaagacacggctgtctattactgtgcgagggcgactaatgccgacgtctgggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +11785 JY8QFUQ01DD2N3 unproductive (see comment) Homsap IGHV4-61*02 F 883 89.09 196/220 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-15*01 F 2 10 7 X 10.7.X [1.17.38.11] CARDPQGYL*WW*LPLFC#MDVW out-of-frame - stop codons Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaacccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaaccngttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagacccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11786 JY8QFUQ01CPIEP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11787 JY8QFUQ01BWMMA productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.37.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 193 in the user submitted sequence), (cause frameshift) tctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggcccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11788 JY8QFUQ01CP0PF productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARDRRPLREFDCW in-frame - ctctggattcaccctctccagctatgctatgcactgggtccgccagtctcccggcaaggggctagagtgggtggcagctatttcatatgatggaagtaaaatatattacgcagactccgtgaggggccgcttctccatctccagagacagttccaagaacactctgcatttgcaaatggacagcctgagacctgaggacacggctacatattactgtgcgagagatagacggccacttagggagtttgactgttggggccagggaaccccggtcgccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11789 JY8QFUQ01BHYO1 No results +11790 JY8QFUQ01CO6TY unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactanttccccgaaccggtgacggtgtcgtgaactc +11791 JY8QFUQ01CQUFJ productive Homsap IGHV3-48*01 F 1075 100.0 216/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11792 JY8QFUQ01BGTEO productive Homsap IGHV3-9*02 F 873 89.4 194/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-8*02 F 2 8 8 20 8.8.20 [1.17.38.11] CARDLWLCSGGECYHRGGFENW in-frame + ctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcaagagatctgtggctttgtagtggtggtgaatgctatcatcggggtggttttgagaactggggccaagggacaagcgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgccctggtccagggcttcttccc +11793 JY8QFUQ01CHY0L productive Homsap IGHV3-9*01 F (see comment) 765 83.87 182/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggagactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +11794 JY8QFUQ01BFKOS No results +11795 JY8QFUQ01AIZWS productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggctt +11796 JY8QFUQ01C4CJF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKDRITIFSYNWFDPW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtccaaggactacttccccgaaccggtgacggtgtcgtggaactc +11797 JY8QFUQ01DH0JE productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11798 JY8QFUQ01BAV34 No results +11799 JY8QFUQ01COL6G productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11800 JY8QFUQ01A5Z17 productive Homsap IGHV3-7*03 F 845 88.37 190/215 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [0.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame + ctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattctctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +11801 JY8QFUQ01CNSWO No results +11802 JY8QFUQ01AYXF7 No results +11803 JY8QFUQ01C7QU9 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 976 94.91 205/216 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARQSVPYTEYFNWFDPW in-frame - tctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcagggggctggagtgggtggcaattatatggcatgatggaaccaataaatactatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacagtgtatctgcaaatgaatagcctgagagccgaggacacggctgtgtattattgtgcgagacagtctgtaccatataccgaatatttcaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11804 JY8QFUQ01AL6UR productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1073 98.64 218/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARDRGPSSSSKMEYDYW in-frame - tctctggtggctccatcaacagtggtggttactactggagttggatccgccagcacccagggaagggcctggagtggattgggtacatctattacagtgggagtacctactacaacccgtccctcaagagtcgagttaccatatcagtagacacgtctaagaaccagttctccctgaagctgagctctgtgactgccgcggacacggccgtgtattactgtgcgagagatcggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11805 JY8QFUQ01BHJ1F No results +11806 JY8QFUQ01CMK2O No results +11807 JY8QFUQ01CHXPU productive Homsap IGHV1-18*01 F 885 90.65 194/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-10*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARVIRTNWLDPW in-frame + tggttacacctttactacctatggcgtcacctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggtaatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacagccgtatattattgtgcgcgagtgattcggaccaactggctcgacccctggggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +11808 JY8QFUQ01CSSV0 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 107 67.31 35/52 nt 7 X X 7.X.X [X.9.X.X] null - No rearrangement found gattcacctttagtagttactggatgcactgggtccagggcttcttccccca +11809 JY8QFUQ01A41PO No results +11810 JY8QFUQ01BYMB6 productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11811 JY8QFUQ01DVLTC unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 876 96.77 180/186 nt 8 8 X 8.8.X [1.17.27.X] null - No rearrangement found ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcca +11812 JY8QFUQ01A5Y86 No results +11813 JY8QFUQ01DO1IH No results +11814 JY8QFUQ01C26JF No results +11815 JY8QFUQ01CSAYF No results +11816 JY8QFUQ01BZDNI productive (see comment) Homsap IGHV4-61*02 F 817 85.59 190/222 nt 84.68 188/222 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 10 7 15 10.7.15 [2.17.38.11] CAKNNNDFGDYDWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'A' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); gtgtctggtggctccatcagcagtgatgattactactggagctggatacggcagtccgccgggaagggactggagtggattgggcgaatttatCaaaagtggcgacacagtgtacaacccctAccctcggggggcgagtcgccatgtcactggacacgtccaagaaccaattctccctgaggttgacttctgtgaccgccgaagacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11817 JY8QFUQ01AO4M7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ6*02 F (see comment) 211 82.26 51/62 nt Homsap IGHD3-9*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARSATGYYDGMDFW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtaggtactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtatgaatagtgatgggagtattataaactacgcggactccgtgaagggccgattcaccatctccagagacaacgcctggaacacgctgtatctgcaaatgaacagtctgggagccgaggacacggctgtgtattattgtgcaaggtctgcgactggctactatgacggcatggacttctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttccccca +11818 JY8QFUQ01DNGX5 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +11819 JY8QFUQ01CQMQ4 unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 412 81.97 100/122 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found Low V-REGION identity (81,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgtttctacttacaccattttctacgcagagtctgtta +11820 JY8QFUQ01BOTUY No results +11821 JY8QFUQ01BOD5Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1076 99.54 217/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD2-2*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKFMGSCSSTSCPQLVRPPG in-frame + cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaagacacggccgtatattactgtgcgaaattcatggggagttgtagtagtaccagctgcccacaactggttcgaccccctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11822 JY8QFUQ01CCXBP No results +11823 JY8QFUQ01CB4XO productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11824 JY8QFUQ01CCZ8L productive (see comment) Homsap IGHV3-7*01 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.16.38.11] CTTTLVWFGEL (see Functionality comment) in-frame + Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggaggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +11825 JY8QFUQ01AH15Z No results +11826 JY8QFUQ01BVEKE No results +11827 JY8QFUQ01A3S3N No results +11828 JY8QFUQ01AP99G productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagcggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11829 JY8QFUQ01AVPHL No results +11830 JY8QFUQ01DN21P productive Homsap IGHV3-48*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDRGGSAYPIFDYW in-frame + ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccc +11831 JY8QFUQ01DNC8V productive Homsap IGHV3-9*02 F 891 90.32 196/217 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + ctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccccaaggatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca +11832 JY8QFUQ01AJ7S8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F (see comment) 87 64.58 31/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11833 JY8QFUQ01BH87Y unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 120 100.0 24/24 nt 6 X X 6.X.X [1.X.X.X] null + No rearrangement found cctctggattcactttcagtaacg +11834 JY8QFUQ01DDAI0 No results +11835 JY8QFUQ01ALDQF No results +11836 JY8QFUQ01B5URA productive (see comment) Homsap IGHV4-34*06 F (see comment) 682 80.19 170/212 nt 79.72 169/212 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 7 7 14 7.7.14 [1.17.38.11] CSRGGQSAGWHSFEAW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 38 of V-REGION: 2 nucleotides (from position 27 in the user submitted sequence), (cause frameshift) tccatggtgggtccctcagggttaccctggacctggatccgccacaccgcagagaagggactggagtggattggtcaaatcaatagtgatggaaggacaacctacaactcggccctcatgggtcgagtcaccatttcaacagacacatccaagaatcagttctcgctgactgtggtttctgttgtcgccgcggacacggcaatgtattattgttcgagaggaggccaaagtgctggctggcactcctttgaagcctggggccagggaacccaggtaatcgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11837 JY8QFUQ01CJGZ4 No results +11838 JY8QFUQ01CTRV5 No results +11839 JY8QFUQ01AH1IP No results +11840 JY8QFUQ01B4N37 productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagtacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11841 JY8QFUQ01ABFEP unproductive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDQVTEDY# out-of-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactgggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +11842 JY8QFUQ01DVKNZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKDMGGDYYIFHYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); cttctggattctcctttagcaactatgccctggcctgggtccgccaggctccagggaaggggctggagtgggtctcaattgttagtggaagtggtactggcacaggccacgcagactCccgtgaggggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggatatgggtggcgactattacatctttcactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccaa +11843 JY8QFUQ01AL4SK unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F (see comment) 603 75.12 163/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,12% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11844 JY8QFUQ01BRC20 No results +11845 JY8QFUQ01AGHVV No results +11846 JY8QFUQ01DNFWA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 661 78.24 169/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (78,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11847 JY8QFUQ01C95LE productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame + tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11848 JY8QFUQ01DIFBM unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 459 72.78 131/180 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (72,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11849 JY8QFUQ01C6FJP productive Homsap IGHV1-58*02 F 930 92.99 199/214 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD3-9*01 F 1 8 8 14 8.8.14 [0.17.38.11] CAAVLAGWGFYYFDFW in-frame - tggattcacctttaaaagttctgctatacagtgggtgcgacaggcccgtggacaacgccttgagtggataggatggaccgccgttggcagcggtaacacagactacgcacagaagttccaggaaagagtcaccattacgagggacatgtccacaagcacagtctacatggagatgatcaacctgggatccgaggacacggccgtgtattactgtgcggcagtcttggccggctggggattctattacttcgatttctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11850 JY8QFUQ01A9LZM productive Homsap IGHV4-4*07 F (see comment) 515 70.59 156/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-1*01 F 2 8 7 16 8.7.16 [3.17.38.11] CARERISSGGGPRHLEPW in-frame + Low V-REGION identity (70,59% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tcactggaggtccggtcaacagtaatgactgctcttggacatggatccgagagtccgccgggaggggactggagtggattggccgtgtccatatgaatggccagaccgactacaatccatccttcggcagtcgtctcgccatgtccattgacacagtcaagaatgaattctcccttcgaatggtctctgtgaccgccgcagacacggccctatattactgtgcgcgagaacgtataagttccggtggcgggccgagacaccttgaaccctggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +11851 JY8QFUQ01BHSKJ productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatgGgacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11852 JY8QFUQ01CYWHB productive Homsap IGHV4-61*02 F (see comment) 677 78.73 174/221 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARDRRRSIAGARHFDSW in-frame + Low V-REGION identity (78,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggccccaccatcgatgatggtgatttgtggacctggatccggcagcccgccggcaagggactggaatggatcggttatgtctatgatgggcggggcaccaactccaacccctccctccggagtcgcgttaccctgtcacaagacacctcaaacaatcagttcttcttgaggttgaagtctgtgaccgcctcagacacggccgtctattactgtgcgcgagaccgccgtaggtcgattgccggagcgagacactttgactcctggggccagggaatcctggtcaccgtcgccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11853 JY8QFUQ01CTZBB productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARDCDSGECNFDYW in-frame + tggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11854 JY8QFUQ01BLSPR productive (see comment) Homsap IGHV1-3*01 F 940 93.06 201/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGRYDSSGRGHEYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'C' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'T' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); gctggatacaccttcaccagtttcagtatccattgggCtgcgccaggcccccggacaAaaggcttgagtggatgggatggatcaaTcggtggcaatggtaacacaaaatattcacagaagttccaggacagactcaccattactagagacacatccgcgagcacagcctacatggacctgagcagcctgagatctgaagacacggctgtctattactgtgcgagagggcgctatgatagtagtggtcgtggccatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11855 JY8QFUQ01B6SNK unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11856 JY8QFUQ01BZ3QE unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 X 10.9.X [1.17.38.11] CTRGSSRGGDMMRTTMS#DFW out-of-frame + tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcgggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +11857 JY8QFUQ01CCYZF productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 10 7 17 10.7.17 [1.16.38.11] CVRLDYYGSGSSYSGLDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) gtctggtggctccatcagtggtactccttactactggggctggatccgccagcccccaggtaagggctggagtggattgggcatgtatatcacagagggaccacctactacaacccgtccctcaagagtcgagtcgccatatccgtagacacgtccgagaaccggttctccctgcagttgaactctgtgaccgccgcagacacggctgtatattactgtgtgagactggattactatggttcgggaagttcttatagtggccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +11858 JY8QFUQ01C7RDZ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD3-10*01 F 1 8 8 19 8.8.19 [1.17.38.11] CARPAFLWFGDLPAEDGFDVW in-frame + ttctggatacagctttaccaattactggatcggctgggtgcgccaggtgcccggaaaaggcctggagtggatggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcagtaccgcctaccttcagtggagcagtctagcgacctcggacaccgccatgtattactgtgcgagaccagcttttctctggttcggggacttaccggccgaggatggttttgatgtctggggccaaggaacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +11859 JY8QFUQ01BZA3D No results +11860 JY8QFUQ01BM2P8 No results +11861 JY8QFUQ01BQLZD No results +11862 JY8QFUQ01AHSIQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 901 92.38 194/210 nt 91.9 193/210 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 7 8 13 7.8.13 [X.17.38.11] CAKGYSSGWYDFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift) attcacctttagtagtttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11863 JY8QFUQ01B1D7U productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CARGIKAVPGAIAYYYYGMDVW in-frame + ctccggattcacctttagtaactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgacaaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagaattcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagaggaattaaggcagtaccaggtgctattgcctactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcttccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11864 JY8QFUQ01BGF48 unknown (see comment) Homsap IGHV4-39*02 F 925 90.99 202/222 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [2.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctctgggtgactccatttccagtactagttattactggggctgggtccgccagcccccagggaaagggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtgggggccagggaacccctggtcaccntctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11865 JY8QFUQ01A0K4F No results +11866 JY8QFUQ01AWSX6 productive Homsap IGHV3-48*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacatggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11867 JY8QFUQ01C95YJ productive (see comment) Homsap IGHV1-3*01 F 840 88.32 189/214 nt 86.92 186/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); tggatacagGcttcactaatcacattatccattgggtgcgccaGggcccccggacaagggcttgagtgggtggGggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11868 JY8QFUQ01ASA99 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 697 92.59 150/162 nt 91.98 149/162 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 2 X 7 13 X.7.13 [X.9.38.11] CARRGSYGSGSYYPW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); gggaaggggctggagtggattgggagtatGcttttatactggggtcaccttctacaacccgtccctcaagagtcgagttaacatttccgtggacacgtccaagagccagttctccctgaggctgagctctgtgaccgccgcagacacggctgtgtatcactgtgcgagacgtggttcctatggttcggggagttattatccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11869 JY8QFUQ01BEEO9 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 940 93.06 201/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.16.38.11] CAISSGYYSTGYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'CA' (2 nucleotides at position 82 to 83 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggatttaccttcagtctctatagaatgaactgggtccgccaggctccagggaagggactggagtggtctcatccattCAtctagtaccagtagttacatttattatgcagacccagtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11870 JY8QFUQ01BHIQA productive (see comment) Homsap IGHV3-7*01 F 863 87.5 196/224 nt 87.05 195/224 nt Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [3.17.38.11] CVRGQVGANPLTTG in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 and Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift); agccctctggggttcaaccctttggtcactattGggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgtcgagaactcactatatttacaaatgaacagcctgagagacgacgacacggctgtatattactgtgtgagaggtcaagtgggagctaatcccttgactactggggccagggggaccctggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11871 JY8QFUQ01BI9J9 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatCggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11872 JY8QFUQ01DS89P No results +11873 JY8QFUQ01AYCDB No results +11874 JY8QFUQ01B1Q4T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +11875 JY8QFUQ01AWPED productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgagacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11876 JY8QFUQ01DVQNE No results +11877 JY8QFUQ01C9JK6 productive (see comment) Homsap IGHV3-11*01 F 973 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD6-13*01 F 1 8 8 9 8.8.9 [2.17.38.11] CARGSSWYRSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'GGAGGGACT' (9 nucleotides at position 91 to 99 in the user submitted sequence), (do not cause frameshift); gcctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcaaacatcaatagtGGAGGGACTagtgggaggaccatatattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacaacctaagagccgaagacacggccttctattactgtgcaagagggagcagctggtaccgctcctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctaagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11878 JY8QFUQ01DCH1D productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11879 JY8QFUQ01BBJPY productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1004 95.87 209/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARHVGNSGFDSSQFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'GA' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); gttctggatacagctttaccacctGActgggatcggctgggtgcgccCaaatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatctcatccgaaaagtccatcagtaccgcctacctgcagtggagcagcctgacggcctcggacaccgccatgtattactgtgcgagacatgtgggaaatagtggcttcgactctagtcaatttgactactggggccagggaacccccgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11880 JY8QFUQ01BJE4C productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +11881 JY8QFUQ01BA4UC No results +11882 JY8QFUQ01AOTOC productive Homsap IGHV3-11*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARRLLSSGWPPHEWGSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtgactactacatgtcgtggatccgccaggctccaggaaaggggctggagtgggtctcatacattagtagtagtggtaattccatatactacgcagactctgtgaggggccgattcaccacctccagggacaacgccaagaattcgatatatctacaaatgaacagcctgagagccgacgacacggccgtttatttttgtgcgagaagacttctgagcagtggctggccaccccacgagtggggctcctggggccagggaacccacgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11883 JY8QFUQ01AN6PU productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +11884 JY8QFUQ01AA27V productive Homsap IGHV4-59*08 F 917 92.09 198/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame - tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11885 JY8QFUQ01CM142 No results +11886 JY8QFUQ01BQXPV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame + ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga +11887 JY8QFUQ01CQ9IE productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 833 87.16 190/218 nt 86.24 188/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [2.16.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) cctccgggagttcaccttagtagtttctggatgcactgggtccgcaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11888 JY8QFUQ01CRTE6 unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1115 100.0 224/224 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFFGLL# out-of-frame + stop codons cttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11889 JY8QFUQ01DMLOV productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11890 JY8QFUQ01BEKLK productive Homsap IGHV4-61*03 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 10 7 12 10.7.12 [1.17.38.11] CTRHPKSNVEGDSW in-frame - tccctggtggctccgtcagcagtggtagttatttctggagctggatccggcagcccccagggcaggggctggaatggatcggttatgtctataacaatgggaacaccaattacaacccttccctcaagagtcgagtcaccatttctatagacacgtccgagaatcacgtctccctgaagctggcctctgtgaccgctgcggacacggccgtgtactactgtacgaggcacccgaagtctaatgtagagggtgactcctggggccagggagccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11891 JY8QFUQ01BH3X1 productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + cctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11892 JY8QFUQ01CEVW7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11893 JY8QFUQ01A6X8C No results +11894 JY8QFUQ01AP01Y unknown (see comment) Homsap IGHV1-2*02 F 551 91.54 119/130 nt 8 8 X 8.8.X [X.17.10.X] null + No rearrangement found ggatacaccttcaccggcacctatatacactgggtgcgacaggcccctggacaagggcttgagtgggtgggattaatcaaccctagcagtggtggcacagagtctgcacagaagcttcagggcagggtca +11895 JY8QFUQ01C583V productive (see comment) Homsap IGHV3-30*01 F 874 89.04 195/219 nt 88.13 193/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARDSVPRASEAAYHFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 214 to 214 in the user submitted sequence), (cause frameshift); gcctctggattcGtccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttaCtttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11896 JY8QFUQ01AKHC5 productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame - ctctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11897 JY8QFUQ01B42UT productive Homsap IGHV3-9*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11898 JY8QFUQ01CC0WF productive Homsap IGHV3-11*06 F, or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F 402 92.55 87/94 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 X X 16 X.X.16 [X.X.31.11] CARDPVGISGSVNWFDPW in-frame + ctctggattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccgagggcttcttcccca +11899 JY8QFUQ01DCV1U No results +11900 JY8QFUQ01BJERG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 913 91.67 198/216 nt 90.74 196/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [2.16.38.11] CAKRLQAVADDAFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 2 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) gcctctggattcatctttagtagctatgccatgggctggtccgccaggctccagggaagggctgagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgagcagcctgagagccgaagacacggccatatattactgtgcgaaaaggttgcaagcagtggctgatgatgcttttgatttctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11901 JY8QFUQ01AP1TI productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 894 91.12 195/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-7*01 F 3 8 7 15 8.7.15 [1.16.38.11] CIADLPDSAENYPFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 58 of V-REGION: 9 nucleotides (from position 88 in the user submitted sequence), (do not cause frameshift) cctctggattcacttttagtggcgcctggatgagctgggtccgccaggctccagggaagggctggagtgggttggccgtgttagaagcggtgggacaacagactaccctgcacccgtggaaggcagattcaccatctctagagatgatcgaaaaaacacgttgtatctggaaataagtagcctgaaaatcgaagacacagccgtatattactgtatcgcagatttgcccgactcggcagagaactatccctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc +11902 JY8QFUQ01C6CX9 No results +11903 JY8QFUQ01DN6YG productive (see comment) Homsap IGHV3-7*01 F 835 88.26 188/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F 136 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 7 10 8.7.10 [1.17.37.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 92 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 98 of V-REGION: 1 nucleotides (from position 194 in the user submitted sequence), (cause frameshift) ctctggattcatctttggacactattggatgagttgggtccgccagattccagggaagggtctggagtgggtggccaacatacaacaagataggaagaattattatctggactctgtgaagggccgatttaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgagacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggantcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11904 JY8QFUQ01BRDEV unproductive Homsap IGHV4-31*06 F 821 85.91 189/220 nt 85.45 188/220 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-16*02 F 1 10 7 X 10.7.X [1.17.38.11] CARRSRGPIQGTPFDH## out-of-frame + in CDR2-IMGT at codon 64 of V-REGION: 'AGTCCCCACTAC' (12 nucleotides at position 102 to 113 in the user submitted sequence), (do not cause frameshift); tctctggagactccgtcaccggaactacttcgtactggagttggatccgccagagcccagggaagggcctggagtggattgggtacgtcttttacaatgagAGTCCCCACTACagcacctactacaggccgtccctcaggagtcgagtcactatttcagtagacacgtctaggaaccagttttccctggaactgagctctgtgactgtcgcggacacggccatgtatttctgtgcgagacgatcccgggggcccatccaggggacaccctttgaccactggggccccgggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaaccgtggtcgtcgcatgcctggtccagggcttcttccccca +11905 JY8QFUQ01CDM6X productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +11906 JY8QFUQ01B5RAR No results +11907 JY8QFUQ01BGC5I productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*08 F (see comment) 769 84.26 182/216 nt 83.33 180/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 1 8 7 13 8.7.13 [2.17.38.11] CASVRPSGERFFDFW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'C' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); gtctctggtggctcgctcacgggtttcaagtggggctggatccggcagcccccaTggggagggactgCaattggattggacatatctctttcgttggggacaccagttatgacccttccctcaggagtcgagtcaccatttcagtcgacacgtccaagaaccagttctccctgaaactgaactctatgactcctgcggacacggccgtctattactgtgcgagcgtgcgtccttcgggagaacggttcttcgacttctggggcctgggaaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +11908 JY8QFUQ01BQZF6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 781 83.78 186/222 nt 82.88 184/222 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [3.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); caatgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11909 JY8QFUQ01BHETC No results +11910 JY8QFUQ01CLHYU productive (see comment) Homsap IGHV3-33*03 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11911 JY8QFUQ01DMPG1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcgatcttcccccttggcaccctcctccaagagcacctcctggggggcacagcggccctgggctggcctggtcaggcactacttccccgaaccggtgacggtgtcgtcggaactca +11912 JY8QFUQ01AQXHN productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggtaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11913 JY8QFUQ01DNQEI productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 905 90.83 198/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame - ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11914 JY8QFUQ01BPU5X unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 625 93.06 134/144 nt 90.97 131/144 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 7 1 X 7.1.X [2.X.38.11] CVSDLAGQKGF## out-of-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01BPU5X ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'T' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 38 of V-REGION: 75 nucleotides (from position 28 in the user submitted sequence), (do not cause frameshift) gcctcaggattcaccttcagtagctacacagatcacgcggactccgtgaaTgggccgattcaccatctccagagacaacgccaagaacaagctgCtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11915 JY8QFUQ01DMK96 productive Homsap IGHV3-48*02 F 896 90.37 197/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [1.17.38.11] CARGQKWLQVLRWFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +11916 JY8QFUQ01AN9TH productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASDLGGQKSYW in-frame + ctctggattcacctttagtgactattggatgagctgggtccgccaggctccagggaaggggctagagtgggtggccaacataaatagagatggaagtgagcaacactatgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccc +11917 JY8QFUQ01B9YIT productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11918 JY8QFUQ01CNS5P productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1010 97.64 207/212 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [0.17.38.11] CARGGGYYFVAIDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +11919 JY8QFUQ01A4B5Y No results +11920 JY8QFUQ01ANBT8 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 135 56.35 71/126 nt 8 8 X 8.8.X [1.17.7.X] null + No rearrangement found stop codons ctctaaattcacctttagcaactatgccatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttc +11921 JY8QFUQ01C7C09 No results +11922 JY8QFUQ01DHFSJ productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame + tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11923 JY8QFUQ01B2TR5 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +11924 JY8QFUQ01CM25P unproductive (see comment) Homsap IGHV4-4*07 F, or Homsap IGHV4-59*10 F (see comment) 380 82.3 93/113 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 3 X X X X.X.X [X.X.37.11] CAREFEIWSRPAL*S#W out-of-frame - stop codons Low V-REGION identity (82,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggtggctcgatcagtggagtcgagtcatcctgtcagtagacacgtccaagaacctgttctccctgaacctgaggtctgtgaccgccgcggacacggccgtgtactactgtgcgagagaattcgaaatttggtcgcgtcctgcactttgatcagtggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11925 JY8QFUQ01BXDIA No results +11926 JY8QFUQ01BFEVB productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 644 93.84 137/146 nt 93.15 136/146 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 1 8 X 12 8.X.12 [1.8.31.11] CARRDVGLHAFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 72 nucleotides (from position 54 in the user submitted sequence), (do not cause frameshift) gttctggatccaattttaactacgactggatcggctgggtgcgccagatgcccggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgcttttgatctgtggggccaggggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11927 JY8QFUQ01CC9GA productive Homsap IGHV3-48*02 F 900 90.78 197/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARDHWDNNGYHWFDPW in-frame - ctctggactcatcttcagtgacaacagcatgaactgggtccgccaggctccagggaaggggctggagtggattgcatacatcagtgctggtagtgtaatgatatactacgcagactctgtgatgggccgattcaccatctccagagacaatgccaagaattcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtatattactgtgcgagagatcattgggacaacaatggttatcactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccgaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11928 JY8QFUQ01BM7QO unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 94 52.24 70/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11929 JY8QFUQ01CSP1R productive Homsap IGHV3-11*01 F 874 89.04 195/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARDDSCSGGSCYEYW in-frame - acctctggattcagtttcagtgactactacatgagttggatccgccaggctccagggagggggctggagtgggtttcatatattgatagcggtggtaccgccatgtactactcagactccgtgaagggccgattcaccatctccagggacaacgccaagaagtcactgtttctgcaaatgagtagcctgagagccgaagacgcggccgtgtactattgtgcgagagatgactcttgtagtggtggtagctgttacgaatactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11930 JY8QFUQ01B5SAT productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt 98.62 214/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.16.38.11] CARDFFIGGYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccGttcagtagctatagcatgaactgggtccgGccaggctccagggaagggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11931 JY8QFUQ01DVWWV productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactgggaccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactc +11932 JY8QFUQ01CKHYH productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 849 87.0 194/223 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD4-23*01 ORF 3 8 10 14 8.10.14 [1.17.38.11] CSRRSTLVTGYVFDKW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggaatcaactttcgtgatcatgccatgagctggttccgccaggttccagggaaggggctggagtgggtaggtttcattagaagttctcaatacggtggagatacagaatacgccgcgtctgtggaaggcagattcaccatctcaagagacgattccaaaagcatcgcctatttggatatgaatagcctgaaaatcgacgacacagccctatattactgttcccggaggtcgacgttggtgactggatacgtctttgacaagtggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11933 JY8QFUQ01CR951 No results +11934 JY8QFUQ01AUXA6 productive Homsap IGHV4-30-4*07 F, or Homsap IGHV4-31*01 F or Homsap IGHV4-31*02 F or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F or Homsap IGHV4-31*06 F or Homsap IGHV4-31*07 F or Homsap IGHV4-31*08 F or Homsap IGHV4-34*09 F or Homsap IGHV4-59*06 F (see comment) 253 75.27 70/93 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 X X 18 X.X.18 [X.X.31.11] CARSAYCGADCYSADYLQHW in-frame - Low V-REGION identity (75,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctctggtggctccgtcagcaacacgtctaagaaccaattctccctgaagttgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +11935 JY8QFUQ01AELDS productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 835 88.26 188/213 nt 87.79 187/213 nt Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD4-23*01 ORF 2 8 7 8 8.7.8 [1.17.38.11] CGRGDGGDLW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcacggttgaggattatggcgtgagctgggttcgccaagttccagggaaggggctggagtgggtctctggtcttaatttgaatggtgccacaggttatgcaaagtccgtgacgggccggtttaccatctccagagacaacgccaagaactccctgtatttggaaatggatagtctgagagtcgaagacacggccttctattattgtgggagaggggacgggggtgacctctggggccggggaatcctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11936 JY8QFUQ01ALQBA No results +11937 JY8QFUQ01C6MAS unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 828 87.1 189/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGFSAWGQDAFDI## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttgggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11938 JY8QFUQ01AB3G5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 942 92.27 203/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARQSFDFAWQWQVDYYFEYW in-frame + ctctggtggctccgtcagcagtagcacttactactggggctggctccgccagtccccagggaaggctctggagtggattgggactatccatcatagtgggagcacctaccagaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaggaaccagttctccctgaggctgagctctgtgaccgccgcagacacggctctttattactgtgcgagacaaagctttgatttcgcgtggcagtggcaggtagattattactttgaatactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtcggtcatcgcctgcctggtccagggcttcttcc +11939 JY8QFUQ01AY8MO productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 857 89.62 190/212 nt 89.15 189/212 nt Homsap IGHJ6*02 F (see comment) 157 72.58 45/62 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [0.17.38.11] CARGHRNPGVWDLGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); acagtgggtccttcagtggttacctctggacctggatccgccagtTcccccgggaaggggctggagtggattggagaaattaattatagtgggagaaccaactacaacccgacccttgagagtcaagtcaccatttctgtagacacgtccaagaaccaattctccctgaagcttacctctgtgaccgccgcggacacggctgtctattactgtgcgagaggtcacagaaatccgggagtttgggacctcggtctggacgtctggggccaggggaccacggtcatcgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11940 JY8QFUQ01BQGF2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CANELGYCSGG# out-of-frame - ctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11941 JY8QFUQ01BGB91 No results +11942 JY8QFUQ01B4712 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11943 JY8QFUQ01BSKS0 No results +11944 JY8QFUQ01APE2N unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1055 100.0 212/212 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [0.17.38.11] CASANYDYVWGELSL#DYW out-of-frame - stop codons ctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11945 JY8QFUQ01C1Z35 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 928 91.78 201/219 nt 90.41 198/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); gcctctggattcaTcgttcagtagctactggatgcactgggtccgccaagctccagggaaGggggctggtgtgggtgtcacgtagtaataCcgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11946 JY8QFUQ01C5Q2O productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + tctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatcccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +11947 JY8QFUQ01BYM54 productive (see comment) Homsap IGHV3-33*03 F 909 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD4-17*01 F 1 8 7 13 8.7.13 [1.17.38.11] CVRGQGLRGGALDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) cgtctggattcaGccttcagtagttatgccatgcactgggtccgccaggctccaggcaggggactggagtgggtggcacttatatactatgatggaagtactaatactttgcagactccgtgaggggccgattcatcctctccagagacaactccaagagaaccctttatctggaaatgaacagcctgcgagccgaggacacggctgtatattactgtgtgagaggccagggattacggggaggtgctcttgatgtctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgcggaactcag +11948 JY8QFUQ01CP0ZY productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11949 JY8QFUQ01CDZX3 No results +11950 JY8QFUQ01A4ICZ No results +11951 JY8QFUQ01CXJ2U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11952 JY8QFUQ01DOZ40 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 80 51.13 68/133 nt 8 6 X 8.6.X [1.17.12.X] null - No rearrangement found ctctggattcaccttcagctcccattggatgagctgggtccgccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11953 JY8QFUQ01C6WJS productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); gtttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11954 JY8QFUQ01B4LPF productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11955 JY8QFUQ01C555O unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1110 100.0 223/223 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFFGLL# out-of-frame + stop codons ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +11956 JY8QFUQ01BMO6L productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11957 JY8QFUQ01BG7VS No results +11958 JY8QFUQ01AQMRJ unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-49*02 F or Homsap IGHV3-49*04 F 120 76.19 32/42 nt 8 X X 8.X.X [0.5.X.X] null - No rearrangement found tggattcagcctcgccacttatagtatgagttgggtccgcca +11959 JY8QFUQ01CP6CD productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 866 88.24 195/221 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 2 10 7 16 10.7.16 [1.17.38.11] CTNDRSMAVRATHAFHIW in-frame + tctctggtgactccattggtagcagtgcctactactggggctgggtccgccagcccctcgggaaggggctggagtggattggaagtatctattatggtggcaacacctactacaacccgtccctcaggagtcgagtcagcatttccgcagacacgtccaagaaccagttctccctgcatctctactccgtgaccgccgcagacacggctctgtattactgtacgaatgaccgttcgatggccgttcgtgcaactcatgcttttcatatctggggcctagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11960 JY8QFUQ01DGVDO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 155 to 155 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgactataccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccGagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11961 JY8QFUQ01AZJZS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [2.17.38.11] CARAYSGPGPYYFDYW in-frame - gcctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11962 JY8QFUQ01ADD0I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [2.17.38.11] CARDRLTISALDYW in-frame - gcctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcgatcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11963 JY8QFUQ01DFDVP unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 770 83.49 182/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagccccgaggacacggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11964 JY8QFUQ01ABYO5 productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CATSPSDFDRRWGYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); cctctggatttagctttagaaccttttggatgagctgggtccgccaggctccagggagGggggctggagtgggtggccaacataaAagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11965 JY8QFUQ01DD9P0 productive Homsap IGHV3-30*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDELPWDTIEYYLDYW in-frame + cctctggattcaccttcaatacctattctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11966 JY8QFUQ01C0163 No results +11967 JY8QFUQ01DSWQX productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 912 90.13 201/223 nt 89.24 199/223 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tgtctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaAggggctggagtggaTttgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11968 JY8QFUQ01AKBXE productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [2.16.38.11] CVRRGMVAGRYDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 72 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagttatagcatgcactgggtccgccagactccagggaagggactggagtggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11969 JY8QFUQ01CF9JY unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKEEGATGVYYVDH# out-of-frame - gcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactgggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11970 JY8QFUQ01BX4H4 productive Homsap IGHV4-4*07 F 854 88.84 191/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 3 8 7 10 8.7.10 [1.17.38.11] CAKDIQDEDNYW in-frame + tctctggtggctccgtcaatggcatttactggagttggattcgacaatccgccggaaagggactggagtggattgggcgcatccataccagtgggagcaccaactacaacccctccctcaaaagtcgagtcaccatgtcgatagacacgtccaagaaccagttctccctaaggttgacctctgtgaccgccgcggacacggccatttattactgtgcaaaagacatacaggatgaggataattactggggccagggagccctggtcaccgtctccgcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +11971 JY8QFUQ01DRMJJ productive (see comment) Homsap IGHV3-11*01 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +11972 JY8QFUQ01CDUFD productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 919 91.32 200/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CTRQTGNYYYFGVDVW in-frame - gcctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11973 JY8QFUQ01CNBO4 No results +11974 JY8QFUQ01CMRUS No results +11975 JY8QFUQ01CUTRF productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaCcctttggttattatggcatgaactgggtccgccaagctccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11976 JY8QFUQ01DMCIU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 940 93.06 201/216 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11977 JY8QFUQ01BU84D productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-2*01 F 2 8 7 12 8.7.12 [2.17.38.11] CAVSTTTWGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); gtctatggtgggtccttcagtggttactactggagctggatccgccagcccccaggggaggggctgcagtggattggaagagtcaatcatagtggaagcaccagctacaacccgtccctcaagagtcgagtcaccatgtcactagacacgtccaagacccacCttttccctgaagctgacctctgtgaccgccgcggacacggctgtgtattactgtgcggtgtctactaccacctgggggtggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11978 JY8QFUQ01BTSZN productive (see comment) Homsap IGHV4-31*06 F 979 93.67 207/221 nt 93.21 206/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [2.17.38.11] CARDRGPSSSSKMEYDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'C' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); gtctctggtgCcctccgtcagcagtggtagtttctactggacctggattcgtcagcacccagggaagggcctggagtggattgggtacatctattacagtgggagcgcctactacaacccgtccctcaagagtcgagttgccatatcaatagacacgtctaagaaccagttctccctgaacttgagttctgtgactgtcgcggacacggccgtttattactgtgcgagagatcggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +11979 JY8QFUQ01C8YSA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVMWGVTGPIDPFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctttacctactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactgggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11980 JY8QFUQ01DDP4N productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +11981 JY8QFUQ01AS99Y unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 866 89.67 191/213 nt Homsap IGHJ5*01 F 102 66.67 34/51 nt Homsap IGHD5-18*01 F 1 8 7 X 8.7.X [1.17.38.11] CAREFRAPSLARYGMDV## out-of-frame - tcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccntgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctgggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11982 JY8QFUQ01BGTYY unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 495 69.59 151/217 nt 69.12 150/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] VHT#AFW out-of-frame + Low V-REGION identity (69,59% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctgaggacaactttggtgaacacgccatgggatggatccgccagtctccgggggggaAttcttcagtgggtcgctgcgatcagtggtgacggactgacggcgtttcacgcagacttcgtggagggtcgattcagcatctccagagacaatcccataaacactctttttctgcaaatgaacagcctcagagtcgaagattcgggtgtctattttgtgcacacactgccttctggggccggggatcccgagtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +11983 JY8QFUQ01BGYPI No results +11984 JY8QFUQ01CLMSI productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 820 86.3 189/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAKVGNLYFFEYW in-frame - gcctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11985 JY8QFUQ01DAXG2 productive Homsap IGHV3-7*01 F 882 89.86 195/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +11986 JY8QFUQ01CLAU5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11987 JY8QFUQ01BB8IM productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 880 88.29 196/222 nt 86.94 193/222 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-19*01 F 2 10 7 16 10.7.16 [2.17.38.11] CTNDHSMAVSAKHAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'AA' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift); gtctctggtgcctccGatgagcaCgtagtgcatactactggggctgggtccgccagAAcccccgggaagggggccggagtggattgggagtgtctactatggtgggagcacctactacaacccgtccctcaagagtcgggcctccatttctgtcgacacgtccaggaacgagttctccctgaggctgaactctgtgaccgccacagacacggctatgtattactgcacgaacgaccattcaatggcagtctctgctaagcatgcttttgatgtttggggtccagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11988 JY8QFUQ01DKOB5 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 872 89.77 193/215 nt Homsap IGHJ3*02 F (see comment) 187 86.0 43/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tatatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaatagtcgagtcatcatatcgatagacacgtccaagaaccaggtctccctgaagctcttctctgtgaccgccgcggacacgggtgtgtactattgtgcgaggcccacgtatagtagcggccgggacgcctttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11989 JY8QFUQ01CCIG5 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARDCDSGECNFDYW in-frame - tggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +11990 JY8QFUQ01A2S2S productive (see comment) Homsap IGHV1-58*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD3-9*01 F 1 8 8 14 8.8.14 [0.17.38.11] CAAVLAGWGFYYFDFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'A' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); tggattcacctttaAaaagttctgctatacagtgggtgcgacaggcccgtggacaacgccttgagtggataggatggaccgccgttggcagcggtaacacagactacgcacagaagttccaggaaagagtcaccattacgagggacatgtccacaagcacagtctacatggagatgatcaacctgggatccgaggacacggccgtgtattactgtgcggcagtcttggccggctggggattctattacttcgatttctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11991 JY8QFUQ01A3591 productive (see comment) Homsap IGHV3-30*07 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-21*01 F 3 8 8 9 8.8.9 [2.17.38.11] CANEEVPNDWW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); gcctctggattcacgttcaacagttTatggtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacactttgtatctacaaatgcacagcctgagagccgaagacacggccacatattactgtgcgaatgaggaggtcccgaatgactggtggggccagggaaccctggtcaccgtgtcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11992 JY8QFUQ01CDKLK unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcaaggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +11993 JY8QFUQ01BQA57 No results +11994 JY8QFUQ01CITBS productive Homsap IGHV3-7*01 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CATSPSVGPTTVGYW in-frame - cctctggattcacctttagaaactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgacagatggaggtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgccacatcccctagtgtgggacctacgacggtgggctactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +11995 JY8QFUQ01CSDDS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11996 JY8QFUQ01B1Y16 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD2-2*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKDPQQLLAEVNWFDPW in-frame - ctctggattcacttttagaagttatgccatgagttgggtccgccaggctccagggaaggggctagagtgggtctcatctatcagtggtaatggtgataagacaaagtacgcagactccgtgaagggccggttcaccatctccagggacaattttaagaatacgttgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattattgtgcgaaagatcctcagcagctattggcagaggtaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +11997 JY8QFUQ01BKT6G productive Homsap IGHV3-66*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD3-16*01 F 2 8 7 13 8.7.13 [2.17.38.11] CAALHDPPWGWLDPW in-frame - agcctctggattcagcgtcaacaacaactacatgaactgggtccgcctggctccagggaagggtctggagtgggtctcagttatttatagaggtggtaatacattctacacagactccgtgaagggccggttcaccatctccagagacatttccaagaacactttgtatcttcaaatgaacagtctgacaactgaggacacggctgtgtactattgtgcggccctccacgaccctccttggggttggctcgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +11998 JY8QFUQ01BK0R7 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame + gttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag +11999 JY8QFUQ01DTVX5 productive (see comment) Homsap IGHV3-48*01 F 1000 95.43 209/219 nt 94.98 208/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggAtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12000 JY8QFUQ01BTIZE unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDQSCIVGPCGFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +12001 JY8QFUQ01CX200 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [2.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) gcctctggaAttcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12002 JY8QFUQ01CASAF productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 911 90.5 200/221 nt 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagTcccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +12003 JY8QFUQ01AS9TZ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 906 90.45 199/220 nt 89.09 196/220 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD1-14*01 ORF 3 10 7 13 10.7.13 [1.16.38.11] CARHLQYNRHGFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 38 in the user submitted sequence), (cause frameshift) tctctggtggctccgtcagcagtagtcattactactgggctggatccgccagaccccaggAaaaggggctggagtggCtttgggacaatctattatagcggaagcgcctacatcaacccgtccctcaagagtcgagtcaccatttccgttgacatatctaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattactgtgcgagacacctgcaatataatcgacatggttttgatttctggggccaggggacaacggtcaccgtctcttcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12004 JY8QFUQ01AD9HE productive (see comment) Homsap IGHV3-7*01 F 937 92.24 202/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [2.17.37.11] CAISSAYFSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'GT' (2 nucleotides at position 11 to 12 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 171 in the user submitted sequence), (cause frameshift) agcctctagaGTtcagcctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12005 JY8QFUQ01DC901 productive Homsap IGHV1-2*02 F 1029 98.13 210/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-3*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARAIDFGSGDKRGFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacaccttcaccggctactctatacactgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcaaccctaacagtggtggcacaaactatgcacagaaatttcagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggagctgagcaggctgacatctgacgacacggccgtgtattactgtgcgagagccatcgattttgggagtggtgacaaacgggggtttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12006 JY8QFUQ01DNXN3 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + tctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcaggc +12007 JY8QFUQ01DLPSL No results +12008 JY8QFUQ01BJ7AA productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12009 JY8QFUQ01CMQUZ unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame - ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12010 JY8QFUQ01A897D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12011 JY8QFUQ01CUNNM unknown (see comment) Homsap IGHV3-7*03 F (see comment) 696 80.37 172/214 nt 79.44 170/214 nt 7 8 X 7.8.X [1.16.38.X] null + No rearrangement found Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcagtttagtgacttttggatgcactgggtccgccaggctccagggaagggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12012 JY8QFUQ01A4918 unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 133 63.64 49/77 nt 8 X X 8.X.X [1.16.X.X] null - No rearrangement found tctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +12013 JY8QFUQ01CGD6K No results +12014 JY8QFUQ01DHTWB productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12015 JY8QFUQ01DTV3B productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 812 93.51 173/185 nt 92.97 172/185 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.6.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 33 nucleotides (from position 36 in the user submitted sequence), (do not cause frameshift) cctctggattcaccttcagtagttactggatgcactgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12016 JY8QFUQ01A1GHG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CVRDRSGQAVGYW in-frame - tggatacacgtttatgaattactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12017 JY8QFUQ01APIZM No results +12018 JY8QFUQ01A4CXE unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 720 81.57 177/217 nt 80.65 175/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGGN*#FDYW out-of-frame + stop codons Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 155 to 155 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 104 of V-REGION: 'G' (1 nucleotides at position 218 to 218 in the user submitted sequence), (cause frameshift); ctctggatttacatttagtgattataatatgaattgggtccgccgggctccagggaaggggctggaatatgtcgcaaccattacaactgggagtggtcaaatctactacagtgactcagtgagaggccgcttcaccatctctagagacgacgccAaagaattcactttatctgcagatgaacaacctgagaggcgaggacacggctgtctatttttgGtgcgagaggggggaactgattttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +12019 JY8QFUQ01CA9L2 No results +12020 JY8QFUQ01AK4VK No results +12021 JY8QFUQ01A65AM No results +12022 JY8QFUQ01AE45Z productive Homsap IGHV4-61*02 F (see comment) 888 89.09 196/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] XARQGDSSGPWNDYW in-frame + Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgngcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12023 JY8QFUQ01AQNXS unproductive (see comment) Homsap IGHV3-11*01 F 891 90.32 196/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [2.17.38.11] CARDGPPY*YGSHGNSFDQW in-frame + stop codons in FR2-IMGT at codon 50 of V-REGION: 'ACC' (3 nucleotides at position 65 to 67 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'T' (1 nucleotides at position 173 to 173 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 56 of V-REGION: 2 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) cctgctggattcagcttcagtgactactacatgagttgggtccgccaggctccaggggaaggggACCtggagtgggtttcatgcatgcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatTctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttattgatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagccctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12024 JY8QFUQ01BNM8M No results +12025 JY8QFUQ01B9YI8 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 899 88.89 200/225 nt 88.44 199/225 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [2.17.38.11] CTTAPSETYATEYFAMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'GA' (2 nucleotides at position 26 to 27 in the user submitted sequence), (cause frameshift); gcctctggattcactttcagtaatgGAtttggatgagttgggnccgtcaggctccgagggaagggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12026 JY8QFUQ01C7R8G productive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD2-15*01 F 2 10 7 19 10.7.19 [1.17.38.11] CARHLTNSDVVHHFYSGVDVW in-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgcctccatcagtaatgataattatttctgggcctgggtccgccagtccccaaggaagggtctgcagtggattggcagtatgtattatagtgggggcaccttttacgacccgtccctcaagggtcgaatcaagttgtccgttgacgtgtcgaagagccacttcctcctgaacctgacctctgcgaccgccgcagacacggctgtctattactgtgcgaggcatttgaccaactcagatgtggtccatcacttctactccggagtagacgtctggggcctcgggaccacggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12027 JY8QFUQ01B0DN3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12028 JY8QFUQ01BI2HT unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 408 87.62 92/105 nt 86.67 91/105 nt 8 8 X 8.8.X [1.16.1.X] null - No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 48 in the user submitted sequence), (do not cause frameshift) gctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggagggggctggagtgggtctcagccattagtggcagtggtagtcggacatatt +12029 JY8QFUQ01CZB7V productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 88.89 192/216 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); tctggattcacGatttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttaCctggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12030 JY8QFUQ01AFVJE No results +12031 JY8QFUQ01CCPRT No results +12032 JY8QFUQ01BUN9C productive Homsap IGHV1-3*01 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame + tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +12033 JY8QFUQ01CKWIB productive Homsap IGHV1-2*02 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDWGGTYAPLDNW in-frame - tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaaccttgaccagtgacacgtccatcagtacagcctacatggaaatgagcgggctgacgtctgaggacacggccatcttttactgtgcgagagattggggtggcacgtacgctccgcttgacaattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12034 JY8QFUQ01CJ55N productive Homsap IGHV3-48*01 F 1080 99.54 216/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASIFGVVPLGNYYYGMDVW in-frame - ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12035 JY8QFUQ01AHXZ2 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARTETQGGYSYGIDSW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); cctctggattcaacttcagtggcCtataccatgacttgggtccgccaggctccggggaaggggctggagtgggtctcatccattagtagtggcagcaattacacatatttcgcagactctgtgaagggccgatgcaccatctcgagagacaacgccaagaaatcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtgcgagaacggagacccaaggtggatacagttatggcattgattcttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12036 JY8QFUQ01BD4L4 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12037 JY8QFUQ01AV7LU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKYVEGWSYTGGYYNSYAMDVW in-frame - cttctggattcgcctttagccgttatgccatgacttgggtccgccagactccagggagggggctggagtgggtctcaggtctcagtggtagtggtgatagcacatactactcaaactccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggaggggtggtcatatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12038 JY8QFUQ01BVNQE unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARKRVPGGTFYG#DYW out-of-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatgggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12039 JY8QFUQ01BA2X2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12040 JY8QFUQ01B921H productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 847 87.67 192/219 nt 87.21 191/219 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD2-8*01 F 1 8 8 19 8.8.19 [2.17.38.11] CAKVFQVSGEHHFYYYGMNAW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); gcctctggattcatctttagtaattatgccatgagttgggtccgccaggCccccagggagggggctggagtgggtctcaactatcagtgccaatggagacaacacatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacagtgtatatgcaaatgaacagcctgaaagccgaggagacggccgtctatcattgtgcgaaagtcttccaggtgtctggcgaacatcacttctactactatggtatgaatgcctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12041 JY8QFUQ01BI52Z unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-71*03 P or Homsap IGHV3-72*01 F or Homsap IGHV3-73*01 F or Homsap IGHV3-73*02 F 87 90.48 19/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggggtcaccttcagtga +12042 JY8QFUQ01DT9N2 productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12043 JY8QFUQ01A8VFH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1004 95.87 209/218 nt 94.95 207/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); cctctggattcagcttcaatagttactggatgcactgggtccgccaagctccaggGgaaggggctggtgtgggtctcacatattaatattgatgGggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12044 JY8QFUQ01BNYDH productive (see comment) Homsap IGHV4-61*02 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 9 7 15 9.7.15 [1.17.38.11] CARGRTVVTVVDYVDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) tctctggtgctccatcagcagtggtagtttctacCtggagctggatccggcagcccgccgggaagggactggagtggatggggcgtgtctatgccagtggaaccaccaagttcaacccctccctcaagagtcgagtcactttatcagtagacacgtccaagaaccagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacgaacggtggtgactgttgttgactacgttgacttttggggtcagggagtcctggtcaacgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12045 JY8QFUQ01B55L9 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ6*01 F (see comment) 90 60.32 38/63 nt 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFGPY (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*02 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) ccctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttggaccgtactggggccaggaacctggtcaccgtctcctcagctccagccaagggccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12046 JY8QFUQ01DDKG0 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*15 F or Homsap IGHV3-30*17 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAKDFYYGCDYW in-frame + ctctggattcaccttcaggaactatgctatgcactgggtccgccaggctcctggcaaggggctagaatgggtggcttttatatcatatgatggaagtagtcaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaaggataccctgtacttgcacatgaccagtctgagacctgatgacacggccatgtattactgtgcgaaagacttttattatggttgcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +12047 JY8QFUQ01CGQUY No results +12048 JY8QFUQ01B6K1Q productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 868 87.11 196/225 nt 85.78 193/225 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-14*01 ORF 2 8 10 13 8.10.13 [2.17.38.11] CNADVPSPLAQNDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 61 of V-REGION: 'A' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); gcctctgggttcGattttcagtgatgcctggatgagttgggtccgccaggctccagggaaAggctctggagtgggttgcccgtataaaaacttttggtgAacggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcgaaaaaaaggctgtatctgcaaatggacagcctgagaatcgaggacacagccaagtattactgcaacgcagatgtcccgtcaccattagcgcaaaatgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12049 JY8QFUQ01BBN07 productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12050 JY8QFUQ01AOWYY No results +12051 JY8QFUQ01DKKPW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12052 JY8QFUQ01ADMS9 productive (see comment) Homsap IGHV3-7*01 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 8 14 7.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 2 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) cctctggattacttttacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12053 JY8QFUQ01CPG9I productive Homsap IGHV4-61*02 F 956 92.76 205/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame - tctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12054 JY8QFUQ01BFMXR No results +12055 JY8QFUQ01DKR74 productive Homsap IGHV3-7*01 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAYFSTGYW in-frame + cctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa +12056 JY8QFUQ01BINLE productive Homsap IGHV4-4*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [1.17.38.11] CARGKDYYDTTGSLEDGFDIW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctctggtggctccataagaagttactattggagttggatacggcactccgccgggaagggactggagtggatcgggcgcatatatgacagtggtagtacaaactacaatccctccctcaagagtcgagtcagcatgtcagtggacacgtccaagaaccaggtctccctgaagttgatctctgtgaccgccgcggacacggccatgtattattgtgcgagagggaaggattactatgatacaactggctccctcgaggatggttttgatatttggggccaagggacgatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12057 JY8QFUQ01CNU0H productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1025 97.67 210/215 nt 97.21 209/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctctgggtggctccatcagtagttactactggagctggatccggcagAcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12058 JY8QFUQ01BLCL3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 902 90.05 199/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARGEFYYETSGRRGFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); cagcctctggaGttcaccttcactacctcctggatgcactgggtccgccaagctccagggaaggggctaatgtgggtcgcacgtattaataaggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaccacactgtacttggaaatggacagtctgagagtcgaggacacggctatgtattattgtgcaagaggggaattttactatgaaactagtggtcgaaggggttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12059 JY8QFUQ01CXKJE No results +12060 JY8QFUQ01CL9NP No results +12061 JY8QFUQ01B33I4 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] RAKG*SLRPNIELQ#W out-of-frame - stop codons Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); ctctggattcacctttagcagcGtaggccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtaatagtggtggtagtagatactacgcagactccgtgaagggccggttctccatctccagagacagttccaagaacacactgcatctgcaaatgaacagcctgagagccgaggacacggccatatattaccgtgcgaaagggtagagtctacgacctaacatcgagctacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12062 JY8QFUQ01A7OU8 No results +12063 JY8QFUQ01C3609 productive (see comment) Homsap IGHV3-72*01 F 1033 96.4 214/222 nt 95.95 213/222 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-11*01 ORF 2 8 9 13 8.9.13 [1.17.38.11] CVRGLHSNYYGMDVR in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 91 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtagtagagacaagttaacagttacagcacagaatacgccgcgtctgcgaagggcagattcaccatctcaagagatgaatcaaagaactcactgtatctgcaaatgaacagcctgaaaagcgaggacacggccgtgtattactgtgttagaggcctacacagtaattactacggtatggacgtcaggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12064 JY8QFUQ01DDR9P productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 914 89.43 203/227 nt 87.67 199/227 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-11*01 ORF 2 8 10 22 8.10.22 [2.17.38.11] CATDRPYYKNAAGRLWYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 136 to 136 in the user submitted sequence), (cause frameshift); agtgctctggaCttcactttcactaacgcgtggatgagttgggtccgccaggctccaGgggaaggggctggagtCgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaAaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaacgctgctggccgactctggtattactacggtatggacgtttggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12065 JY8QFUQ01DBBY5 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtGactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12066 JY8QFUQ01CEP1K productive (see comment) Homsap IGHV1-69*06 F, or Homsap IGHV1-69*10 F or Homsap IGHV1-69*14 F 814 86.57 187/216 nt 85.65 185/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-8*02 F 3 8 8 22 8.8.22 [1.17.38.11] CARGGKSPRRDIIQGVTVDALDLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); tctggagacaccttcagtagccaagccatcagctgggtgcgacaggcccctggacaaggacttgagtggatgggcgggatcatccctaCtttttgatatgacgaggtacccacagaggttcgagggcagaatcacgattaccgcggacacgtccacgaccacactttacatggaactgagcagcctgaggtctgaggacacggccgtgtaCtttttgtgcgagaggcgggaagagtcctcgtcgtgatattatacagggggtgactgttgatgctcttgatctctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12067 JY8QFUQ01BN8OF productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 609 96.92 126/130 nt 96.15 125/130 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 X 10 8.X.10 [1.3.31.11] CSNGYGDFPRRW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 38 in the user submitted sequence), (do not cause frameshift) gtctggattcaccttcaggagctattggatgagctggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +12068 JY8QFUQ01CV8NL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12069 JY8QFUQ01BYHLS No results +12070 JY8QFUQ01AD2J7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12071 JY8QFUQ01DBBMX unknown (see comment) Homsap IGHV2-5*03 F 186 55.21 106/192 nt 10 7 X 10.7.X [9.17.26.X] null + No rearrangement found gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12072 JY8QFUQ01CMOW4 productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12073 JY8QFUQ01BV30U productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-2*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARVRCVTTSCRGLSYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtaactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccagcataaagcaagatggaagtgagacatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagtccggtgtgtcaccaccagctgccggggcctctcctactttgactcctggggccagggaaccctggtcaccctctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12074 JY8QFUQ01DNI95 No results +12075 JY8QFUQ01B6VLE productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 854 88.84 191/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARVDFYGSSKYKGFDPW in-frame + tctctggtaactccatcacagattattactggagctggctccggcagtctccagggaagggactggagtggattggaaatgtcttttacagtgggagagccaactacaacccctccctcaagagtcgagtcaccatatcagtagccacgtccaggaaccagttctccctgaagctcaggtctgtgaccactgcggacacggccatatattattgtgcgagagttgatttctatggttcgagtaaatataaggggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +12076 JY8QFUQ01BUZUI productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 776 83.71 185/221 nt 83.26 184/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFETW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'T' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tttccggtagttccatcagtagcagtgattactactTggggctgggtccgccagtccccagggaagggtctggagtggattggaagtgtctattacagggggacgcagtacctcaacccgtccctccagagtcgagtttccatttccattggcacgtccaagacgcaattctccctgagactgaggtctgtgaccgccgcagacacggctatgtattactgtgcgagacatcggtcttttggagtgataattgtgaattactttgagacctggggacagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12077 JY8QFUQ01CBIYP productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 93.72 209/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 200 to 200 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaaGtatgctgtatctgcaattgaacagcctgaaaacCcgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12078 JY8QFUQ01BFRFB unproductive Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDGPPYLYGSHGNSFDQ## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggcccagggaaccctagtcaccgtctcctagcctccaccaaggggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12079 JY8QFUQ01A7WRG productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1030 97.69 211/216 nt 96.76 209/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtaactatagcatgactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12080 JY8QFUQ01BNL2E productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1011 97.2 208/214 nt 96.26 206/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagctactaTtttgcactgggtgcgacaggCcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcgaggggacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +12081 JY8QFUQ01BWQCK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 603 85.89 140/163 nt 85.28 139/163 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD6-25*01 F 1 8 4 22 8.4.22 [2.2.38.11] CARYQGDTSGYQDVFYAHYGMDVW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (4 AA in JY8QFUQ01BWQCK ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 41 of V-REGION: 56 nucleotides (from position 38 in the user submitted sequence), (cause frameshift) gcctctggattcacgtttaggggctactggatgcactggagatagtacaagttatgcggactccgtgaagggccgcttcaccatctccagagacaacgccaggagcacattgttcctgcaaatgagcagtctgagagtcgaagacacggccatttattactgtgcacggtatcagggcgataccagtggctaccaggacgttttctacgcccactacggtatggacgtctggggccaagggacctcggtcaccgtctattcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12082 JY8QFUQ01A0Q4J unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 876 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ5*01 F 102 66.67 34/51 nt Homsap IGHD5-18*01 F 1 8 7 X 8.7.X [1.17.38.11] CAREFRAPSLARYGMDV## out-of-frame - in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); cctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccntgaagGggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctgggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12083 JY8QFUQ01CJML0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKKYHYGSGSYLYCFDYW in-frame - gcctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtggtgatgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactgctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12084 JY8QFUQ01AEE83 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 741 83.18 178/214 nt Homsap IGHJ6*02 F 179 77.05 47/61 nt Homsap IGHD2-15*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDKVISAGRDVW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AEE83 ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagtttcactggttttaccgtgatctgggtccgccaggctccaaggaaggggctggaatggatctcatccgtcactactaatggtctcacgtactacgcagactcagtagagggccgattcaacatctccagggacaacgccaacaatttagtgtttctgcaaatgaacagcctgagagtcgaggacactggtgtatattattgtgcgagagataaagtgatctctgccggacgggacgtctggggccaagggaccacggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12085 JY8QFUQ01AJFOA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame + ctctggattctccgtcagtaattactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12086 JY8QFUQ01BMO95 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame + ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggagccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +12087 JY8QFUQ01BVLGG productive (see comment) Homsap IGHV3-7*01 F 982 94.52 207/219 nt 93.61 205/219 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD5-12*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRERGGFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagaaactattggatgagttgggtccgccaggctccagggaaAggggctggagtgggtggccagtataaAaactagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccggagacaacgccaagaactcactgtatctgcaaatgaaccgcctgagagccgaggacacggctatatatcactgtgtgagagatcgagagaggggcgggttcgacccctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12088 JY8QFUQ01CZYLK No results +12089 JY8QFUQ01AEH4G productive (see comment) Homsap IGHV3-48*01 F 855 88.48 192/217 nt 87.56 190/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.16.38.11] CARASTFYYDGSGYRDVFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggcttcagtttgGagtacttataccatgaactgggtccgccaggctccaggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12090 JY8QFUQ01CEH2G No results +12091 JY8QFUQ01BR2B7 No results +12092 JY8QFUQ01CZ28Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcanttccccgaaccggtgacggtgtgcgtggaactca +12093 JY8QFUQ01A08YZ unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 972 94.47 205/217 nt Homsap IGHJ3*01 F (see comment) 124 72.0 36/50 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKSPSQVGYYLD#VG out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccggcaaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcaccatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12094 JY8QFUQ01ALA99 No results +12095 JY8QFUQ01A4MB9 productive (see comment) Homsap IGHV4-61*07 F (see comment) 775 84.02 184/219 nt 83.56 183/219 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); gtctggtggctccgtcagcagtggaaattcctactggacctTggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12096 JY8QFUQ01COFAM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 802 85.39 187/219 nt 84.93 186/219 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-16*01 F 3 8 8 15 8.8.15 [2.17.38.11] CVKGYFGAFPSAWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'TATAAG' (6 nucleotides at position 16 to 21 in the user submitted sequence), (do not cause frameshift); gcctctggactcaccTATAAGtttgtcaattatgccatgacgtgggtccgccaggctccagggaagggtctggagtgggtctcaggtattaatggtaatggtcgtaatacactgtacgcagacttcgcgaagggccggttcaccatctccagagacaattccaaggacacggtgtatttgcagctgaatagactgggggtcgaagacacggccatgtattactgtgtgaaaggttatttcggggcatttccgtctgcctggttcgactcttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12097 JY8QFUQ01CF2WI productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [1.17.38.11] CACYFDSNGFFDYW in-frame + ttctggatacgtctttccctcctactggatcgcctgggtgcgccagatgcccggtaaaggcctggagtggctgggaaccatctatcccggcgactctgacaccacatacagcccgtcattccaaggccaggtcaccatgtcagtcgacacgtccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacagcgccatttactattgtgcgtgttattttgatagtaatggtttctttgactactggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12098 JY8QFUQ01DGPWM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactc +12099 JY8QFUQ01DGSKL No results +12100 JY8QFUQ01CRGE6 No results +12101 JY8QFUQ01CATWA productive Homsap IGHV3-9*01 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame - cctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12102 JY8QFUQ01B8CFK productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame - tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12103 JY8QFUQ01BSK1X productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 930 92.99 199/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-25*01 F 1 8 8 15 8.8.15 [0.17.38.11] CARHEGYNSRYYYFGYW in-frame + tggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12104 JY8QFUQ01B4FE6 productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDGYYYYHSGMDVW in-frame + ctctggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattattgtgcgaaagacggctattattattatcacagcggtatggacgtctggggccaagggaccacggtcatcgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggctccagggcttcttc +12105 JY8QFUQ01C37US No results +12106 JY8QFUQ01BZW42 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [2.17.37.11] CAKNNNDFGDYDWF#PW out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 111 in the user submitted sequence), (cause frameshift) tctcctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatatctattatactgggggcaccgactccaaccctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgaccctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12107 JY8QFUQ01DXG68 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12108 JY8QFUQ01ASEOA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 830 86.43 191/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gcctccgggagttcacctttagtagtttctggGatgcactgGggtccgccaagttcCcaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12109 JY8QFUQ01CHO3D unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 412 88.46 92/104 nt 87.5 91/104 nt 8 8 X 8.8.X [1.16.1.X] null + No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 47 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggagggggctggagtgggtctcagccattagtggcagtggtagtcggacatatt +12110 JY8QFUQ01C7TMB productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12111 JY8QFUQ01BCU1I unproductive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD2-8*01 F 2 10 7 X 10.7.X [1.17.38.11] CARGKWGDKPPFYYGMDV## out-of-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12112 JY8QFUQ01ARUTN productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +12113 JY8QFUQ01DJ5EW productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1085 100.0 218/218 nt 98.62 215/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); cctctggattcaGccttcagtagctatagcatgaactgggtccgccaggctccagggaaGggggctggagtgggtctcatccaAttagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12114 JY8QFUQ01AVOE0 No results +12115 JY8QFUQ01C4C3U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggcccttgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12116 JY8QFUQ01CWOR0 unknown (see comment) Homsap IGHV1-2*01 F, or Homsap IGHV1-2*02 F or Homsap IGHV1-2*04 F or Homsap IGHV1-2*05 F or Homsap IGHV1-46*01 F or Homsap IGHV1-46*03 F (see comment) 259 69.91 79/113 nt 69.03 78/113 nt 8 8 X 8.8.X [0.17.4.X] null - No rearrangement found Low V-REGION identity (69,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); tggatacGaccttcaccgaccactatctgcactgggtccgacaggcccctggacaagggcttgagtggatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12117 JY8QFUQ01DHLEX productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 996 95.0 209/220 nt 94.55 208/220 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [2.17.38.11] CARGEMTAEYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); tgtctctggtggctccatcagcagtgttCaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12118 JY8QFUQ01DE0K1 No results +12119 JY8QFUQ01BEZB3 unproductive Homsap IGHV4-61*02 F 870 88.64 195/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CARDFRRFLQFSG#YW out-of-frame + ctctggtgactccattagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttcggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12120 JY8QFUQ01B1SQ5 productive Homsap IGHV4-59*03 F 899 91.16 196/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-23*01 ORF 3 8 7 9 8.7.9 [1.17.38.11] CARGVTPEGYW in-frame + tctcgggtgactccatcactcctaactcctggagctggatccggcagcccccagggaagggactggagtggattggttatatctattacagtggaatcaccaagcacaacccctccctcaagagtcgagtcgccatttcagtagacacgtccaagaaccaattttccctgaggctgagttctgtgaccgctgcggacacggccgtttatttctgtgcgaggggggtcactccggagggctactggggccagggaatcttagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +12121 JY8QFUQ01CH38P productive (see comment) Homsap IGHV4-61*02 F 956 92.76 205/221 nt 92.31 204/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcaacagtggtaAttttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12122 JY8QFUQ01BKLH1 unproductive (see comment) Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CAK*LAEQRLVPFLR#W out-of-frame + stop codons cctctggattcacctttgatgagcatgccatgcactgggtccggcaagttccggggaagggcctggagtgggtctctggtgttacttggaatagtggtgtcatagactatgcggactctgtgaagggccgattcaccatctccagagacaacgccaggaattccctgtatctacaaatgaacagtctgagaactgatgacacggccttctatttctgtgcaaaatgattggccgagcagcggctggtcccatttttgaggcttggggccagggagtcctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +12123 JY8QFUQ01AG3LY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12124 JY8QFUQ01CAD0L unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 657 77.88 169/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (77,88% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcgactatggcatgacctgggtccgccaggctccagggagggggttggagtgggtcgcatctattaatgccggtggtagtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12125 JY8QFUQ01A2EN2 unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 135 77.78 35/45 nt 8 X X 8.X.X [1.5.X.X] null - No rearrangement found ctctggattcagcctcgccacttatagtatgagttgggtccgcca +12126 JY8QFUQ01CIGYA productive (see comment) Homsap IGHV3-7*01 F 985 95.37 206/216 nt 94.44 204/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 7 8 11 7.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift)in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) tctctggattcaccttagtaggtttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcccctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12127 JY8QFUQ01A5GJK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12128 JY8QFUQ01BUZSL productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 797 84.93 186/219 nt 84.47 185/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) cctccgggagttcaccttagtagtttctggatncactggggtccgcaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12129 JY8QFUQ01A6ZEV No results +12130 JY8QFUQ01DDN7X productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*13 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [2.17.38.11] CARDDFYSSGNYGGFGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtcactatggtatacactgggtccgccaggctccaggcaaggggctagattgggtggcatttatatcatatgatggaagtaatGaggttttacgcagactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12131 JY8QFUQ01C6W6D productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASLNTHAGPGAERSAFDIW in-frame + cctctggattcaccttcagtaactacagaatgaattgggtccgtcaggctccagggaaggggctcgaatgggtctcgtccattaccagttccagtagttacatatactacgcagactcggtgacgggccgattcaccatctccagagacaacgccaaggggtcactctatctgcacatgagctaccttagagccgaggacacggctgtctattactgtgcgagcctaaacacgcacgcgggaccgggagccgaaaggtctgcttttgatatctggggccaagggacaatggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggccttcttccc +12132 JY8QFUQ01B7KC5 No results +12133 JY8QFUQ01AUWE8 productive (see comment) Homsap IGHV3-7*01 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'T' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); cctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggTagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +12134 JY8QFUQ01B98IB No results +12135 JY8QFUQ01C2J66 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 10 7 11 10.7.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + tctctagtgactccatcagcagtactaattactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatgtatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcattcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12136 JY8QFUQ01AP5RM unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 392 76.47 104/136 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (76,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +12137 JY8QFUQ01BLAAL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 826 87.79 187/213 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [X.17.38.11] CIMDLVGRADYW in-frame + ggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgcctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12138 JY8QFUQ01C4PF5 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 953 91.96 206/224 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.38.11] CTHLREEMSYEW in-frame + cctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaagggactggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +12139 JY8QFUQ01DW3PR productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame - cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12140 JY8QFUQ01CVG3H productive Homsap IGHV3-66*02 F 913 91.67 198/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.17.38.11] CAKLADTGEWSNRIFYFW in-frame - gcctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12141 JY8QFUQ01BQ72X productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame + ctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12142 JY8QFUQ01A60V7 productive Homsap IGHV3-48*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGNYYYFGMDVW in-frame + ctctggattcctcttcagtagctttaacatgaactgggtccgccaggttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccatctactactgtgcgagacaaactgggaattattattacttcggtatggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12143 JY8QFUQ01BNVHC unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANYW# out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12144 JY8QFUQ01AG8B1 No results +12145 JY8QFUQ01CIC1B productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 98 of V-REGION: 'T' (1 nucleotides at position 199 to 199 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgaTcgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12146 JY8QFUQ01BVJJA productive Homsap IGHV4-4*07 F 953 93.95 202/215 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt 8 7 9 8.7.9 [1.17.38.11] CARGDWYFDLW in-frame - tctctggtggctccatcattaatcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtagtcataccagtggaagcaccaggtacaacccctccctcaagagtcgagtcaccgtgtcagcagacacgtccaagaaccagttctccctgaagcttagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggagactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12147 JY8QFUQ01AQ8YC productive (see comment) Homsap IGHV3-11*01 F 833 87.16 190/218 nt 86.7 189/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-7*01 F 1 8 8 15 8.8.15 [1.17.38.11] CVRESRSWTGSTLPAYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 97 of V-REGION: 'T' (1 nucleotides at position 195 to 195 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgactattacatgagttggtaccgccaggctccaggtcaggggctggagtggctttcatatataagtcaaactggcaaaaccacatacttcgcagactctgtgaagggccgattcaccatctccagggacaatgccaagacatcagtgtttctgcaaatgaacagcctgagagttTgacgacacggccgtgtatttttgtgtgagagaatctaggagttggactggaagtacacttccagcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +12148 JY8QFUQ01CIG7Q No results +12149 JY8QFUQ01BRXXD unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 110 53.24 74/139 nt 10 7 X 10.7.X [1.17.11.X] null + No rearrangement found stop codons tctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12150 JY8QFUQ01BXZRW productive Homsap IGHV3-48*02 F 828 87.1 189/217 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-16*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARGRYSYAHGMDVW in-frame + ctccggattcacctccatctcctatggcatgcactgggtccgccagattccaggaaaggggctggagtcggttgcatacattagtgatagtaatagcagcatatactatgcagactctgtgaagggccgattcaccatctcccgagacaaagacaagaagtcagtatatctgcaaatgagcagcctgagagacgaggacacggctatttattactgtgcgagggggcgatacagttatgctcacggaatggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12151 JY8QFUQ01A6UFN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD6-13*01 F 3 7 8 11 7.8.11 [1.17.38.11] CAKGPHQYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) cctctggatcacttttaggagtcatatgatgagttgggtccgccagactccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12152 JY8QFUQ01C98OS unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 587 78.24 151/193 nt 8 8 X 8.8.X [1.17.30.X] null - No rearrangement found Low V-REGION identity (78,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaaggactacttccccgaaccggtgacggtgtcgtggaact +12153 JY8QFUQ01CNKPH productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 782 85.12 183/215 nt 84.19 181/215 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CATVRHLGERIFDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift); tctctggggccaccatgagtagtttctactggagctgggttcggcagtccccagggaggggactagagtggattggatttGctttcttacagtgggcccaccaactacaGacccctccctcaagagtcgagtcaacttatcactggacgcggccaacaaacagttctctttgcagctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12154 JY8QFUQ01ADDVJ productive Homsap IGHV3-7*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + cctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctcag +12155 JY8QFUQ01CYW4W productive (see comment) Homsap IGHV3-74*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD2-21*01 F 2 7 8 9 7.8.9 [1.17.38.11] CVRDNYSVDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtaattactgatgcagtgggtccgccaagctccagggaaggggctggagtgggtctcacatattaccagtgatggaagcaccacaacttacgcggactccgtgaagggccgattcaccacctccagagacaacggcaggaacaccctttatctgcaaatgaacagcctgagagccgaggacacggctacatattactgtgtaagagacaactattccgttgatgtctggggccaggggacaatggtcaccgtctccacagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12156 JY8QFUQ01B06BT productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12157 JY8QFUQ01ANCM4 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12158 JY8QFUQ01ASQ57 No results +12159 JY8QFUQ01C8154 productive Homsap IGHV3-48*01 F 1085 100.0 218/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12160 JY8QFUQ01ACCK5 No results +12161 JY8QFUQ01AVH3D No results +12162 JY8QFUQ01B1595 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12163 JY8QFUQ01CE5RG productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 841 87.96 190/216 nt 87.5 189/216 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 7 18 8.7.18 [2.17.38.11] CARADYYDTSAYYLDAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 60 of V-REGION: 9 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) gcctctgggtacagcttgcgaggctctgttttgcactgggtccgccaggcttccgggaaaggactggagtgggttggccgtgtcggaaggcagggcgcgacaacatacgctgcgtcggtgaaaggcaggttcctcatctccagagatgatccagcgaacacggcttatctggaaatgaacagcctgaaaaccgaggacacggccgtctattactgtgctcgcgcagattactatgatactagtgcttattatctcgatgcttttgatatctggggccaggggacaattgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12164 JY8QFUQ01DK3A2 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAARIDSGHYWNAFDIW in-frame - tctggatacagtttcaccaactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctggtgactctgatacccggtacaacccgtccttccaaggccaggtcaccttctccgtcgacaagtccatcaacaccgcctacctgcagtgggacagcctgaagacctcggacaccgccaagtattactgtgcggcgagaattgatagtggtcattactggaatgctttcgatatatggggccaagggacgatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12165 JY8QFUQ01C6C7H No results +12166 JY8QFUQ01BD3IS productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagga +12167 JY8QFUQ01ARIKI No results +12168 JY8QFUQ01CNGNP productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame - ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12169 JY8QFUQ01DBO7O productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12170 JY8QFUQ01CLSK9 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggGggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +12171 JY8QFUQ01CRM77 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12172 JY8QFUQ01CXXEM No results +12173 JY8QFUQ01DPB0D unproductive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 976 94.91 205/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAGDLTGGSVLL*Q*WFK#YW out-of-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); tctagattcaGccttcagtagctataatatgcactgggtccgccaggctccaggcaaAggggctagagtAgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactgggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12174 JY8QFUQ01BBMWB unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found tgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +12175 JY8QFUQ01CZFLE productive Homsap IGHV3-66*02 F 913 91.67 198/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.17.38.11] CAKLADTGEWSNRIFYFW in-frame - gcctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12176 JY8QFUQ01BGTTQ productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGNYYDSGGLDYW in-frame - tccggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcgaataactatcaagccagacgcatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtatattactgtgcaagagggggtaattactatgatagtggtggtcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12177 JY8QFUQ01AU3KK No results +12178 JY8QFUQ01DCIJS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12179 JY8QFUQ01AW82K productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctgaagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12180 JY8QFUQ01ANCOI unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggccctatcggtcttccccccttggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12181 JY8QFUQ01BPYKB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 863 89.3 192/215 nt 87.44 188/215 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 15 8.8.15 [0.17.38.11] CAKNRGSAMADWYFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'AATG' (4 nucleotides at position 85 to 88 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'C' (1 nucleotides at position 144 to 144 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'G' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); ctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaTggggctggagtgggtctcaactattactAATGgtgggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctCccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttaGtttctgtgcgaaaaatagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12182 JY8QFUQ01CFWQ8 productive Homsap IGHV3-11*01 F (see comment) 788 84.86 185/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARYRGSYYDYGGVDVW in-frame + Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggcttcagattccgtgactactacatgacgtgggtccgccaggctccagggaagggtcttgagtggctttcctccatcagcagcggtagtaataccatccactactcagactcggtgaggggccgcttcaccatctccagggacaacaccaggaactcagtggatctgcaaatgaatagtctgagagccgaagacacggccgtctattattgtgcgaggtacagaggcagttactacgactatggcggtgtggacgtctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +12183 JY8QFUQ01BWU1H unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 41 90.0 9/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctcaggatt +12184 JY8QFUQ01B9W7D unproductive Homsap IGHV4-4*01 F, or Homsap IGHV4-4*02 F or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 878 89.45 195/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 88 64.0 32/50 nt Homsap IGHD3-10*01 F 3 9 7 X 9.7.X [1.17.38.11] CARDKDVTARGTFDM## out-of-frame + tctctggtgtctccatcagtagtaattactggtggatttgggtccgccagtccccaggggaggggctggagtggattggagaagtctatcatactgggaccacctattacaacccgtccctgaagagtcgagtcaccctgtcagtagacaagtccaggaatcagttctccctggagatgacttctgtgaccgccgcggacacggccgtgtatttctgtgcgagagataaagacgtgacagctcgtgggacctttgatatgtggggccaggggaacagtggtcaccgtctcttcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +12185 JY8QFUQ01BWFLL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 865 88.58 194/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [2.17.38.11] CARDGRGGDLDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaattcaaagaacacgctcaatcttcaaatgaatagtttgagagttgacgacacggctgtgtattactgtgcgagagatgggcgcggcggtgaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12186 JY8QFUQ01DTXRK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 919 91.32 200/219 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD3-3*01 F 3 8 8 15 8.8.15 [2.17.38.11] CAKQTIFDYYYYGLDVW in-frame - gcctctggattcatgtttagtagctttcccatggcctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatagacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12187 JY8QFUQ01BFWP5 productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYYYYDTNGDYW in-frame - ctctggatttacctttacaaattattggatgagctgggtccgccaggctccagggagggggctggagtgggtggccagcgtaaaacaagatggaggtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggtcctactattattatgatactaatggcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +12188 JY8QFUQ01DCMLJ productive Homsap IGHV3-30*01 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYHFDYW in-frame - ctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttacttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12189 JY8QFUQ01DA17U productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12190 JY8QFUQ01DG6A9 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.13 193/219 nt 87.67 192/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); ttccgggggttcaccgtcagtagccaagTacatgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcattcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12191 JY8QFUQ01AB5OR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12192 JY8QFUQ01ACI6J No results +12193 JY8QFUQ01BWMBN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12194 JY8QFUQ01BMBTQ No results +12195 JY8QFUQ01C4VXF productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12196 JY8QFUQ01CHIJT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12197 JY8QFUQ01B7P7N productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 791 85.58 184/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [0.17.38.11] CVRDLNWSFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12198 JY8QFUQ01BO2V4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 8 8 10 8.8.10 [1.17.38.11] CATWIQSHFDYW in-frame + cctctggattcacatttagtcactataccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagccattaatcaagatgccattaccacacactacccagactccgtgaagggccgcttcaccgtctccagagacaattccaagaacacactctatctgcaaatgagcagcctgagagccgacgacacggccgtatattattgtgcgacgtggatacagtctcactttgactattggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12199 JY8QFUQ01CTSF9 No results +12200 JY8QFUQ01DE1Y0 productive Homsap IGHV3-48*01 F 928 91.78 201/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CTRQTGNYYYFGVDVW in-frame - gcctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12201 JY8QFUQ01CVH72 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 463 68.06 147/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (68,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12202 JY8QFUQ01CTPB4 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + tctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12203 JY8QFUQ01CHH44 No results +12204 JY8QFUQ01CGOF5 productive (see comment) Homsap IGHV4-55*03 P (see comment) 733 82.33 177/215 nt 80.93 174/215 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 9 7 15 9.7.15 [1.16.38.11] CARDQSVYTAGSYFDSW in-frame - Potentially, because of detected insertion/deletion however the closest V is a pseudogene Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 169 to 169 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) ctctggtgactccatgagtagcgacacgtggtggagctgggtccgccagacgccagagaagggactgaatggattggggagatcaatcaaagagggacgacctcctacaacccgtccctcaggagtcgagtcgtcctgtcagtgggcgagtccaaaaaTccaattctcCcctgaggctgacctctgtgaccgccgcggactcggccatctattattgtgcgagagatcagtctgtctatactgcgggaagttactttgactcctggggccagggaacgctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12205 JY8QFUQ01A2XE9 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); ctctggattcaTcgttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaataCcgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12206 JY8QFUQ01BSGCG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-7*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKVFQVPGEHHFYYFGMNVW in-frame - cctctggattcatgtttaggaactatgccatgagttgggtccgccaggctccagggagggggctggagtgggtctcaactattagcaataatggaagccacacatactacgcagactccgtcaagggccggttcaccatctccagagacaattccaagaacacggtgtatatgcagatgaacaggctgagagtcgaggagacggccctgtactactgtgcgaaagtcttccaggtgcctggcgagcaccacttctactacttcggaatgaatgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12207 JY8QFUQ01B24MT productive (see comment) Homsap IGHV3-9*01 F 937 92.24 202/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [2.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); gcctctggattcaccGtttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccCctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12208 JY8QFUQ01AFQKU productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-16*01 F 2 8 10 11 8.10.11 [1.17.38.11] CTTRRGTYATFYW in-frame - cctctggattcactttcagtgacgcctggatgaggtgggtccgccaggctccagggaaggggctggagtgggttgcccttattaaaagcaagactgatggtggaacaacagactacgctgcgcccgtgcaaggcagattcaccatctcaagagatgattctaagaacacactatatttgcaaatggacaacctgaaaaccgaggacacagccgtgtattactgtaccacacgacgtgggacttatgctacattctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12209 JY8QFUQ01B38BV productive (see comment) Homsap IGHV4-61*02 F 956 92.76 205/221 nt 92.31 204/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcCccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12210 JY8QFUQ01CGBHU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctcaggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcaggc +12211 JY8QFUQ01CCB9O unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F (see comment) 644 77.06 168/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (77,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctcgggattcaacttcaagtccaacaccatgaattgggtccgccaggctccagggaaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12212 JY8QFUQ01C1CD6 No results +12213 JY8QFUQ01BWB0K unproductive Homsap IGHV3-9*02 F 901 90.41 198/219 nt Homsap IGHJ6*04 F (see comment) 83 60.34 35/58 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [2.17.38.11] CGKDMRPGGMDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) gcctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccagggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12214 JY8QFUQ01CT9HA productive (see comment) Homsap IGHV1-18*01 F 817 87.32 186/213 nt 86.38 184/213 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-16*01 F 2 8 8 24 8.8.24 [0.16.38.11] CARDGYCSTKNCFAKTDFVWGTINYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 207 to 207 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) tggttacagcttttaccaatatggtattagctgggcgcgacaggcccctggacaagggcttgagtggatggatggatcagcacattcaatgatgtcacataccttgcacagaagttccagggcagagtcaccatgaccactgacacctccacgagcacagcctacttggaactaaggagcctgacatctgacgacacggccgtttaCtttttgtgcgagagacggatattgtagtacgaagaattgcttcgccaagaccgacttcgtttgggggaccataaactactggggccagggatccctggtcgccgtctcttcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12215 JY8QFUQ01C73E8 No results +12216 JY8QFUQ01DDY3T No results +12217 JY8QFUQ01BDULP No results +12218 JY8QFUQ01B3IOP productive Homsap IGHV3-72*01 F 894 89.24 199/223 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 10 12 8.10.12 [1.17.38.11] CARDLGNGWGYDYW in-frame + ctctggcttcatcttcagtgaccactatatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagagttgcatctaacacttacgccacagaatacgccgcgtctttcaaaggcagattcgtcatctcaagagacaattcaaggaactcattgtttctccaaatgaacagcctgaaaaccgacgacacggccatgtattattgtgctagagatctgggcaatggctggggctatgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12219 JY8QFUQ01DKCLG productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 687 80.37 172/214 nt 79.91 171/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccaCggcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcgggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12220 JY8QFUQ01DCGRP productive (see comment) Homsap IGHV3-30*01 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD3-16*01 F 3 7 8 15 7.8.15 [2.17.38.11] CARVITAYYYYYAMEVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) gactctggatcaccttcaatagcgttactatgcactgggtccgccaggctccaggcaaggggctagagtgggtggctattatatcatatgatggaagtaagacagactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagagaacgctgtttctgcagatgaacagcctgagagttgaggacacggctgtgtattactgtgcgagagtgattaccgcttactactactactacgctatggaggtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12221 JY8QFUQ01C1C90 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 838 87.21 191/219 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARLRSFGDYPLDVW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc +12222 JY8QFUQ01CSDXL unproductive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1066 97.33 219/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - stop codons tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtagtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12223 JY8QFUQ01CN2LN unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt 99.07 212/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWGELSL#DYW out-of-frame - stop codons in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacCccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctcCcctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +12224 JY8QFUQ01A2U3J unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 358 86.32 82/95 nt 8 5 X 8.5.X [1.17.X.X] null + No rearrangement found cctctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc +12225 JY8QFUQ01BX0V8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'CCTT' (4 nucleotides at position 22 to 25 in the user submitted sequence), (cause frameshift); tctggattcaacctcaatagcCCTTttgggcatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12226 JY8QFUQ01BHPPA productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 992 95.79 205/214 nt 94.39 202/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFYYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagGctactatatacactgGggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggnggtgccaCcaagntacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagacttttactactggggccagggaaccctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12227 JY8QFUQ01ANX39 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 693 80.18 174/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD5-12*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKSPDSGYDSNWLDPW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaacttggcgaagttcgccatgagctgggtccgccaggctcctgggaaggggctggagtgggtctcagagatcagtggctccggtagtaaagtcggatatgcggagtccgtgaagggccgattcaccatctccaaagacaattccaagaacacattgtacttgcaaatgaccgacctgagacccggcgacacggccatttattactgtgcgaaaagtcctgatagtggctacgattctaactggctcgacccctggggcctgggaaccctggtcaccgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12228 JY8QFUQ01A5D4P productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVPHQNIIYLDYW in-frame - tctggattcgactttagcagcgcttccatggcctgggtccgccaggctccagggaaggggctggagtggatctcagctgtcagtggacgtggtgacaacaccttctacgcagcctccgtgaagggccggttcaccatctccagagaccattccaagaacacgctgtggcttcaaatgaacaacctgagagccgaagacacggccctatattactgtgcgagggaagtcccacatcaaaatataatctaccttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12229 JY8QFUQ01ACXPV productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARRLNNYDSGEYAMDVW in-frame - tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12230 JY8QFUQ01AAQO2 No results +12231 JY8QFUQ01CJGTX No results +12232 JY8QFUQ01A0931 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12233 JY8QFUQ01AD002 No results +12234 JY8QFUQ01AX0VD unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt 8 7 X 8.7.X [1.17.38.X] null - No rearrangement found in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +12235 JY8QFUQ01BY72S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKCKAPGKVDWFDPW in-frame - cctctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctggtaaggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12236 JY8QFUQ01AUPMO unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt 93.58 204/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [2.16.38.11] CARDTLEVVSNMDDAFDF## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 42 of V-REGION: 'GT' (2 nucleotides at position 41 to 42 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtcgttatagcatgaactgggGTccggccaggctccagggaagggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctgggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12237 JY8QFUQ01ATTMO productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcttccccgaaccggtgacggtgtccgtggaactcaggc +12238 JY8QFUQ01B9G18 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 119 54.62 71/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +12239 JY8QFUQ01AMXFZ No results +12240 JY8QFUQ01C7W4Y No results +12241 JY8QFUQ01DC5GC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 813 86.92 186/214 nt 85.98 184/214 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.37.11] CAKESLVRGVISYYFDDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 131 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctggttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12242 JY8QFUQ01BW28C productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.18 205/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaanttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcaccctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12243 JY8QFUQ01C1AQG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12244 JY8QFUQ01A7MBK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 933 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [2.17.38.11] CTKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtagatactGggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12245 JY8QFUQ01AWSIU productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + cctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaacctcag +12246 JY8QFUQ01A7M44 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1085 100.0 218/218 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFD#PW out-of-frame + cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12247 JY8QFUQ01CUTTR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - ctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12248 JY8QFUQ01BEYEJ productive Homsap IGHV3-72*01 F 926 90.62 203/224 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-8*02 F 2 8 10 17 8.10.17 [1.17.38.11] CTRDTTDTGGQSFNGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggtttccccttcagtgaccacttcatggactgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctggggccaggggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12249 JY8QFUQ01AJGDO productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [1.17.38.11] CACYFDSNGFFDYW in-frame + ttctggatacgtctttccctcctactggatcgcctgggtgcgccagatgcccggtaaaggcctggagtggctgggaaccatctatcccggcgactctgacaccacatacagcccgtcattccaaggccaggtcaccatgtcagtcgacacgtccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacagcgccatttactattgtgcgtgttattttgatagtaatggtttctttgactactggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12250 JY8QFUQ01CDEVZ No results +12251 JY8QFUQ01AQMC4 unproductive (see comment) Homsap IGHV3-49*02 F (see comment) 599 73.57 167/227 nt 73.13 166/227 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*02 F 1 8 10 9 8.10.9 [2.17.38.11] CAGLLSHFDIW in-frame - stop codons Low V-REGION identity (73,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); attgatgtggtcgggcttcggggcttacacgaatgacttggttccgcttgcctccagggaggggcctggGaattggtaggtttcatcaggagcacgggaaacggtgggacaacagagtacgccgcgtctgtgagaggcagagtcttcatctcaagagatagatccaacaatgtcgcctatctacaaatgaacaatctgaagaccgaggacaccgccatatattattgcgctggactcctttcccattttgacatatggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtctccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12252 JY8QFUQ01B9US6 unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*04 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*03 F or Homsap IGHV3-66*04 F (see comment) 264 72.38 76/105 nt 8 7 X 8.7.X [1.17.1.X] null + No rearrangement found Low V-REGION identity (72,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggcttcaccgtcaataacaactacatgggctgggtccgccaggctccagggaaggggctggagtgggtcatcgcctgcctggtccagggcttcttccccca +12253 JY8QFUQ01CXO7E productive (see comment) Homsap IGHV3-66*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [2.17.38.11] CVGDRQRDNYFAYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); gcctctggactcaccttcagtggccCagtacttagactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcaacacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12254 JY8QFUQ01DBCAP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 256 90.32 56/62 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAHGPSAAPHYYYYYGLEAW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcacctttaccaactatgGgcatgaggtgggtccgccaggctccagggaaggggctggagtgggtctcagatattagcgctggtggcgataacacatactacgcagactccgtgaagggccggttcaccatctccagagacaatttcaggaacacgctgtatctgcaaatgagcagcctgagagccgaggacacggccctttattactgtgcgcatgggcccagtgcagcaccccattactactactattacggtttggaagcttggggccaagggaccaaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12255 JY8QFUQ01BH7NG productive Homsap IGHV3-66*02 F 948 93.93 201/214 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD6-13*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARDSPYSSGWSDGFDVW in-frame + ctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatatcagtggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaagaacacggtgtatcttcagatgaacagtctgagagctgaggacacggctgtgtattactgtgcgagagatagtccatatagcagcggctggtctgatggctttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgctggtccagggcttcttccc +12256 JY8QFUQ01BXSH4 No results +12257 JY8QFUQ01DNBGA productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 861 88.18 194/220 nt 86.82 191/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [3.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 19 to 20 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 41 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) aggcctcctggattcaccCTttgggttattatggcatggactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12258 JY8QFUQ01A0OMH productive (see comment) Homsap IGHV3-74*03 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); ctctggattcacGtttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctcgcctggtccagggcttcttccccca +12259 JY8QFUQ01BVD0A productive (see comment) Homsap IGHV3-33*03 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); cgtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtGgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12260 JY8QFUQ01BIEKD productive Homsap IGHV3-43*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARSDLSMVRDLDYW in-frame + ctcaggattcacatttgctgaatataccatgcactgggtccgtcaagttccggggaagggtccggagtgggtctctcttattagttgggatggtggcagcacatactatgcagactctgtgaagggccgattcaccatctccagagacaactccaagaacacgctgtttctgcaaatgaatagcctgagagtcgaggacacggctctgtattactgtgcgagatccgacctctctatggttagagatcttgactattggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggctcttccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12261 JY8QFUQ01APYPD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggattcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12262 JY8QFUQ01DRI0O unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 41 90.0 9/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctccggatt +12263 JY8QFUQ01BJ66M productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctagattcacctttaatggttactggatgagttgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12264 JY8QFUQ01A0VIE productive (see comment) Homsap IGHV3-30*01 F 878 89.45 195/218 nt 88.53 193/218 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [1.17.38.11] CACGHMRDGYDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'CA' (2 nucleotides at position 99 to 100 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 156 to 156 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtCAaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcCccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12265 JY8QFUQ01AIK4Y productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +12266 JY8QFUQ01CNFRH productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt 95.85 208/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggctacttccccgaaccggtgacggtgtcgtggaactcag +12267 JY8QFUQ01DGWBL productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 13 8.8.13 [2.17.38.11] CARGGGGKSIPLDNW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); gcgtctggcttcacgttcagtagttatggcatgcaatgggtccgccaggctccaggcaaggggctggagtgggtggcagttaAtttggtatgatggaagtaataaatattatgcagactccgtgaagggccgattcgacatctccagagacaattccaagaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatgtaccattgtgcgagaggcggcggtggtaagtccattccacttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12268 JY8QFUQ01AULL8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [1.17.38.11] CVKDRDFLWGSYRLQLESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcacctttagtagctatggcatgagttgggtccgccagtctccaaataagggactggagtgggtcgcaggcattagtgcaaatggtggcagtataaattatctggacgccgtgaagggccggtttatcatctctagagacaattccaagaacacgttgtatctgcaaatggacagcctgacagtcgaggacacggccgtttattactgtgtgaaagatcgtgattttctttgggggagctatcgtcttcaacttgaatcttggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +12269 JY8QFUQ01CZT5A unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 704 81.6 173/212 nt 81.13 172/212 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD1-7*01 F 2 8 7 X 8.7.X [1.17.37.11] CARLDGHFDL# out-of-frame + Low V-REGION identity (81,60% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 129 in the user submitted sequence), (cause frameshift) tctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctgggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12270 JY8QFUQ01A3I1V productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*08 F 782 93.3 167/179 nt 92.74 166/179 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD1-26*01 F 1 X 7 18 X.7.18 [X.14.38.11] CARGWAQQAGATFVGWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 54 of V-REGION: 'TTGG' (4 nucleotides at position 39 to 42 in the user submitted sequence), (cause frameshift); ggatccgccagcccccagggaaggggctggagtggcatTTGGgggaaaatcaatcatagtggcaggaccaactacaacccgtccctcaagagtcgagtcaccatatcaatagacacgaccaacaaccagttctccctgaagttgacctctgtgaccgccgcggacacggctgtatatttctgtgcgagaggttgggcccaacaagcgggagctacgtttgttggctggttcgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12271 JY8QFUQ01B3P0G productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.16.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) ctctggattcacctttaccacctccgccatggcctgggtccgccaggtccagggaaggggctggagtgggtctcaactattagacctagtagtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12272 JY8QFUQ01CFR5M productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12273 JY8QFUQ01BU31Q productive (see comment) Homsap IGHV3-9*01 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRQAYYHDSSAYFFSRYWYFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcacttttgatgactctgccatgcactgggtgcggcaagctccagggaaggGgcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacgccaagaagtccctgtttctgcaaattaaaagtctgagagttgaggacacggccttatattattgtgtgaggcaagcgtattaccatgatagcagtgcttacttcttctcccgctactggtacttcgatctctggggccgtggcaccccggtcactgtctcttcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12274 JY8QFUQ01AYEC2 No results +12275 JY8QFUQ01A6R0X productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt 99.08 215/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaGggggctggagtgggtctcatccaAttagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12276 JY8QFUQ01DEFGF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt 84.4 184/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [1.17.38.11] CTKTRVVLGITFPFYIYGLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); cctctggattcacgttcgacaactatgccatgagctgggtccgccaggcaccaggaaaggggctggagtgggtctccagtattagtggtaatggagaaattgtacaccacgcagacgccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgTtttttgcaaatgaatggagtgagagacgacgacacggccatttactactgtacgaaaacacgcgttgtgttgggaattacatttccgttctatatctatggtctggacgtctggggccaagggaccacggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12277 JY8QFUQ01CY2LK No results +12278 JY8QFUQ01B6KZL unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 839 86.43 191/221 nt 85.97 190/221 nt 8 10 X 8.10.X [1.17.37.X] null + No rearrangement found in FR3-IMGT, from codon 94 of V-REGION: 2 nucleotides (from position 193 in the user submitted sequence), (cause frameshift) ctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttcccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgatgtcgtggaactcag +12279 JY8QFUQ01BUAG1 No results +12280 JY8QFUQ01DP3B2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12281 JY8QFUQ01ACRP3 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 950 93.12 203/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +12282 JY8QFUQ01BHE62 productive Homsap IGHV3-74*03 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12283 JY8QFUQ01ANKL9 No results +12284 JY8QFUQ01CCTG1 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 922 90.22 203/225 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-22*01 F 1 8 10 X 8.10.X [2.17.38.11] CATDRPYYKTLLADS#YYYGMDVW out-of-frame - tgctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaacgctgctggccgactctggtattactacggtatggacgtttggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12285 JY8QFUQ01AXXI5 No results +12286 JY8QFUQ01B6FTY No results +12287 JY8QFUQ01CXMEU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12288 JY8QFUQ01AVBAG productive (see comment) Homsap IGHV3-48*01 F 921 92.52 198/214 nt 91.59 196/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [0.17.37.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 95 of V-REGION: 'G' (1 nucleotides at position 186 to 186 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 174 in the user submitted sequence), (cause frameshift) ctggattcaccctcagtagcaacagcatgaactgggtccgccagactccggggcaggggctggagtgggttgcacacattagtagtagcagcgataccatatactacgcagactctgtggggggccgattcaccatctccagagacaatgccaagaactcactgcatctgcaatgaacagtctgaGgagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +12289 JY8QFUQ01ATA9W productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.57 187/216 nt 84.72 183/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); gtctctggggactccattagtggCttactattggacgtggatccggcagAgccccagggaagggactggagtggattggaaatgtccattacacCtgggagtaCccaagtacagcccctccctnaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12290 JY8QFUQ01AGVPX productive (see comment) Homsap IGHV4-4*07 F 827 87.44 188/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 7 9 8.7.9 [1.17.38.11] CARDSGDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'CC' (2 nucleotides at position 84 to 85 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); tctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtcCCaaaaccagtgggaCccccccactacaaacccttcctcaagagtcgaatcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccatttttttctgtgcgagagactccggggactttgactactggggcccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12291 JY8QFUQ01B66RM productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 824 86.7 189/218 nt 85.78 187/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-10*02 F 2 8 7 14 8.7.14 [2.17.38.11] CVGEGGGRGVSAFEFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); atacccctgagttcaccgtcagGttacaactgcctaagctggatccgccaggctccagggaagggcctagagtgggtctcagAttttttgtagcgctaatggaccatactacgcagactccgtgaagggccgattcaccaccgccagagacaatagtaagaacatactgtatcttcaaatgaacagcctgagagccgaggacacggccgtgtactactgtgtgggcgaaggtggtggtcgtggagtgagtgcttttgagttctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12292 JY8QFUQ01A17DH unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 103 52.99 71/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12293 JY8QFUQ01CW1RS No results +12294 JY8QFUQ01CXZPX unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDPRDYCSGGYCFVGAFDI# out-of-frame + Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaggaattattactggagctggatccggcagTcccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaaggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca +12295 JY8QFUQ01CIAL0 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12296 JY8QFUQ01CRM51 productive (see comment) Homsap IGHV4-59*03 F 791 85.58 184/215 nt 84.65 182/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.37.11] CARGRTVVTVVDYVDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 86 of V-REGION: 'C' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) gtctctggtgactccattagtggttactattggacgtggatccgacagcgcccagggatgagcctggagtggattggacaagtccattacactgggagcaccaagtacagccctccctcaagagtcgagtcaccatttctgttgacatgtccaagaaccCaattcaccctcatcttgacctctgtggccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttgttgactacgttgacttttggggtcagggagtcctggtcaacgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +12297 JY8QFUQ01AJ4K5 productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CATAYYYDNRGHYQEDPFDYW in-frame + ctctggattcacctttagtagccattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaactgcggtattttatgtggagtctgtgaagggccgattcaccatctccagagacaatgtcaggggctcacttcatctgcaaatgaatggcctgagagccgaggacacggctgtatattactgtgcgacagcttattactatgataatagaggtcattaccaagaggatccctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12298 JY8QFUQ01CCSBL productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGDYYDSGGLDYW in-frame + tccggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtgattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtctcgcctgcctggtccagggcttcttcccccag +12299 JY8QFUQ01CYDEI unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [2.17.38.11] CARKRVPGGTFLW#DYW out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggGggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggacctttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12300 JY8QFUQ01BCS5Q productive (see comment) Homsap IGHV4-4*07 F 872 89.77 193/215 nt 87.91 189/215 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 7 12 8.7.12 [1.17.38.11] CARFSSYGDTFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'A' (1 nucleotides at position 210 to 210 in the user submitted sequence), (cause frameshift); tctctgatgggtccatcggaagttactactggacttggatccggcagcccgccgggaaggcaatggagtCggatcgggcgtgtctttagaactCgggaacacgaattacaAacccctccctcaagagtcgggtcaccatgtcagttgacacgtccaagaatcaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgAttttactgtgcgagattctcgtcctacggtgacacctttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12301 JY8QFUQ01DF8ZC productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION tctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12302 JY8QFUQ01BHGJG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt 86.24 188/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 2 7 8 14 7.8.14 [2.17.38.11] CAREVPHQNIIYLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) cctgctggattcgacttagcagcgcttccatggcctgggtccgccaggctccagggaaAGggggctggagtggatctcagctgtcagtggacgtggtgacaacaccttctacgcagcctccgtgaagggccggttcaccatctccagagaccattccaagaacacgctgtggcttcaaatgaacaacctgagagccgaagacacggccctatattactgtgcgagggaagtcccacatcaaaatataatctaccttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +12303 JY8QFUQ01CBD1A productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 811 85.84 188/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12304 JY8QFUQ01AQ5S2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 867 89.72 192/214 nt 88.79 190/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.16.38.11] CAKDQSCIVGPC#FDYW out-of-frame - in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 43 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tccgaattcatccttgacagttatgccatgagttgggtccgcaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggtttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12305 JY8QFUQ01BBSNW productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12306 JY8QFUQ01DW9X4 No results +12307 JY8QFUQ01DM0QJ unproductive Homsap IGHV3-48*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.16.38.11] CARGQNGYKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccaggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12308 JY8QFUQ01C3WRL productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 84.62 187/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtGactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12309 JY8QFUQ01BP7V3 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift); ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagaCtacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12310 JY8QFUQ01B8NNC No results +12311 JY8QFUQ01AYVUG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12312 JY8QFUQ01AGNO8 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDI* out-of-frame + ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctagggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +12313 JY8QFUQ01AVQGZ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); cctctggattcacCctttggttattatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12314 JY8QFUQ01DGVV1 productive (see comment) Homsap IGHV3-7*01 F 1014 95.91 211/220 nt 95.45 210/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); aggctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12315 JY8QFUQ01BSAA3 No results +12316 JY8QFUQ01BVDC3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 651 77.13 172/223 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD3-10*01 F 3 10 7 20 10.7.20 [2.17.38.11] CATSTTRVRGAIRNLVTWFDPW in-frame - Low V-REGION identity (77,13% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctcgggtgtctccacaaccagtcaatttaacttctgggtctggatccgccagcctccagggaaggcaccggagtggatagccagttcacgttatggagggaagacgttttacaatccgtcgctcgagagtcgggtcaacatgtctctgggcacgtctaagaatcagttttacctgaacctgatgtctgtgaccgccgcagacacggctgtttatttctgtgcgacgagcaccactcgagttcggggagccatcaggaaccttgttacctggttcgacccctggggcccgggaactcgagtgactgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12317 JY8QFUQ01DFMAZ unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CASLNTHAGPGSRRS#FDIW out-of-frame + ctctggattcaccttcagtaactacagaatgaattgggtccgtcaggctccagggaaggggctcgaatgggtctcgtccattaccagttccagtagttacatatactacgcagactcggtgacgggccgattcaccatctccagagacaacgccaaggggtcactctatctgcacatgagctaccttagagccgaggacacggctgtctattactgtgcgagcctaaacacgcacgcgggaccgggcagccgaaggtctgctttgatatctggggccaagggacaatggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggccttcttcccc +12318 JY8QFUQ01CQO2O productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 94.17 210/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 89 of V-REGION: 'A' (1 nucleotides at position 178 to 178 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaatatgctgtatctAgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12319 JY8QFUQ01ASOW0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [0.17.38.11] CAFSRALTGKWIDYLDHW in-frame + tggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +12320 JY8QFUQ01C3RLJ productive Homsap IGHV3-48*02 F 891 90.32 196/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [1.17.38.11] CARGQKWLQVLRWFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12321 JY8QFUQ01AY1CS No results +12322 JY8QFUQ01BV8LF productive (see comment) Homsap IGHV3-7*03 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 7 8 8 7.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) cccggattcattttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +12323 JY8QFUQ01DG4MA No results +12324 JY8QFUQ01AOJOM unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYE#DYW out-of-frame - in FR3-IMGT at codon 96 of V-REGION: 'G' (1 nucleotides at position 190 to 190 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagaGgacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacatgcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12325 JY8QFUQ01CTG21 unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F (see comment) 255 57.48 123/214 nt 8 8 X 8.8.X [0.17.38.X] null - No rearrangement found Low V-REGION identity (57,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12326 JY8QFUQ01BNHUN productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaaggggcccatcggtcttgcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12327 JY8QFUQ01AK5BM productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.37.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtccttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12328 JY8QFUQ01B8W39 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 704 81.6 173/212 nt 81.13 172/212 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.37.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,60% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 129 in the user submitted sequence), (cause frameshift) tctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12329 JY8QFUQ01DO2BI No results +12330 JY8QFUQ01B6ZEZ unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 805 100.0 162/162 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 X 7 X X.7.X [X.9.38.11] CARSRTFYGSANY## out-of-frame - gggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12331 JY8QFUQ01CMK7J unproductive (see comment) Homsap IGHV1-2*02 F 804 86.45 185/214 nt 85.98 184/214 nt Homsap IGHJ3*02 F 182 84.0 42/50 nt Homsap IGHD3-16*02 F 2 8 8 X 8.8.X [0.17.38.11] CARHFS*HQRRL#DFDIW out-of-frame + stop codons in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); tggatacagcttcaccgactTtttacattcattgggtgcgacaggaccctggacaagggcttgagtggatggggtggaccaaccctaaaaatggtggcacgttcattacgctgaagtttcagggcagggtcactatgtccagggacacgtccatgaccacagtctatatggagatgagcaggctgagatctgacgacacggccatttattactgtgcgagacatttttcgtgacaccaacgacgtctgtgattttgatatctggggccaggggacaaaggtcaccgtctntttagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcatcgcctgcctggtcagggcttcttccc +12332 JY8QFUQ01BKZBL unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.16.38.11] CAKDQSCIVGPCGFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12333 JY8QFUQ01B0BMU productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 750 82.06 183/223 nt 81.17 181/223 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARRHYGEGLFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift); atttccgggtagttccatcagtagcagtgattactactggggctgggtccgccagtccccagggaagggtctggagtggattggCaagtgtctattacaggggggacgcAgtacctcaacccgtccctccagagtcgagtttccatttccattggcacgtccaagacgcaattctccctgagactgagctctgtgatcgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12334 JY8QFUQ01CWXBJ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1040 97.71 213/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame - cgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12335 JY8QFUQ01CUILV No results +12336 JY8QFUQ01BCD74 productive (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 671 78.9 172/218 nt 78.44 171/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARVTSDRYFYYGMDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (78,90% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); gctctggattcagtataagtgacgattatatgagttgggtccgccaggctccaggcaaggggctggcttGgggtatcatacatcagtgccagtggcgagacgatagactacgcagactctgtgaggggccgattcgccatctccagggacagcgctgagaattcactctatttggagatgaacagtctaacagacgaagattccggaatgtattattgtgcgagagtgacgtcggaccgctacttctattacggaatggacgtctggggccaggggaccactgtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12337 JY8QFUQ01DLNQ2 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12338 JY8QFUQ01A3DG1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcacctttagcaactatgccatgagttgggtccgccaggctcaagggaaggggctggactgggtctcagatattagtaatagtggtggtgacacattctacgcaggctccgtgaagggccgcttcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcacgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12339 JY8QFUQ01CQY9U unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 108 53.33 72/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12340 JY8QFUQ01CYB7H productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcaccctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcttggaactca +12341 JY8QFUQ01CS823 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1060 100.0 213/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWGELSL#DYW out-of-frame - stop codons tctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12342 JY8QFUQ01AXK7W productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 523 89.92 116/129 nt 88.37 114/129 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 X 12 8.X.12 [1.3.31.11] CVKDISRSGCFEYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'G' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 37 in the user submitted sequence), (do not cause frameshift) tctggattccagtttagcaactatgccatgagctggggccgggtcaccaGtctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12343 JY8QFUQ01A3HM7 No results +12344 JY8QFUQ01CHOYS No results +12345 JY8QFUQ01CXUFF productive (see comment) Homsap IGHV4-39*02 F (see comment) 699 80.0 176/220 nt 79.09 174/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 10 7 15 10.7.15 [1.16.38.11] CAIHNYYGSGRNYFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'A' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift) tctctggagtctccgccatcggcaccagttccttctAggggctgggtccgccagcccccagggaagggctggagtggatcggagctgttcattacagtggaagtatctcttacatgccggccctcaagagtcgactcaccatgtccttagacacgtcaaaaggtcacttgtccctgagactgacctcagtgacctccgcagacacggctatgtactactgtgccatacacaactactatggatcggggagaaactactttgaccactggggacagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12346 JY8QFUQ01B2F6Z unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGS# out-of-frame + ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtgggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccggctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +12347 JY8QFUQ01B33G0 No results +12348 JY8QFUQ01AF3QZ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 927 92.17 200/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) gtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12349 JY8QFUQ01DI3MQ unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt 94.12 208/221 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD1-1*01 F 1 10 7 X 10.7.X [1.17.38.11] CARRGRCG*LLVLRSL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctagtgactccatcagcagtactaattactactGggggctggatccgccagcccccagggaaggggctggagtggattgggagtatgtatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgagacgggggagatgcggataactactggtacttcgatctctgggggccgtggcaccctggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +12350 JY8QFUQ01BH6WY productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactca +12351 JY8QFUQ01AGH15 No results +12352 JY8QFUQ01BTE0F productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12353 JY8QFUQ01BZ3C1 No results +12354 JY8QFUQ01DGZL8 productive Homsap IGHV3-48*01 F 810 86.18 187/217 nt Homsap IGHJ6*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 1 8 8 8 8.8.8 [1.17.38.11] CVRGAGLDVW in-frame - ctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaggggctggagtgtgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctggacgtctggggccaagggaccacggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12355 JY8QFUQ01AEZL4 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F 836 87.91 189/215 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD4-17*01 F 2 8 7 18 8.7.18 [1.17.38.11] CASLVTINDNGDYTWAFDVW in-frame + tggatggtgggtccttcagtaataagtattggagttggattcgccagttcccagggaaggggctagagtggattggagaaatcaaccaaagtggaagcaccaactacaatccgtccctcatgagtcgagtcaccatctccatagacacgtccaagatgcagttctccctgaagttgacctctgtgaccgccgcggacacggctgtctattattgtgcgagtttagtgaccattaatgacaacggtgactacacgtgggcttttgatgtctgggcccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +12356 JY8QFUQ01B9ZOB unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 923 91.74 200/218 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CASDLGGQKSY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12357 JY8QFUQ01C2BC0 No results +12358 JY8QFUQ01B4F0J No results +12359 JY8QFUQ01CYNV8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 866 88.24 195/221 nt 87.78 194/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [3.16.38.11] CARDRLTISALDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) aggcctcctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaatgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12360 JY8QFUQ01BZKKR No results +12361 JY8QFUQ01BK9SP productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 920 90.95 201/221 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 1 10 7 12 10.7.12 [1.17.38.11] CAWGWFGLNYFDYW in-frame - tctctggtggctccgtcagaagtaccagttactactggggctggatccgccagcccccagggaaggggctggagtggattagtaacattcattctagtggaaccacctactacaacccgtccctcaacagtcgagtcaccatgtccgtaaacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcggacacggctgtatattactgtgcatgggggtggttcggactgaactactttgactactggggcccgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12362 JY8QFUQ01COABY unproductive Homsap IGHV4-34*10 F 818 86.98 187/215 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD4-23*01 ORF 3 8 7 X 8.7.X [1.17.38.11] CARNTNYGGNSGDYFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccaagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12363 JY8QFUQ01AQMNE productive (see comment) Homsap IGHV3-66*02 F 907 92.02 196/213 nt 90.61 193/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.16.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcagtagcagcttcatgacttggtccgccagctccaggaaaggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12364 JY8QFUQ01CWRHM unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 739 91.91 159/173 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found ctctggagtcacctttagtgactattggatgagctggatccgccaggctccagggaaggggccggagtgggtggccaacatagagcaagatgggagtgagataaattatgtggactctgtgaagggccgattcaccatctccagagacaacaccgagaatgcactgtatctgc +12365 JY8QFUQ01BSWUC productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12366 JY8QFUQ01DFMZ6 productive (see comment) Homsap IGHV3-30*08 F, or Homsap IGHV3-30*16 F 928 91.78 201/219 nt 90.87 199/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 3 8 8 14 8.8.14 [2.17.38.11] CARGKAGHTHYGLDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); gcctctgcattcaccttcagtagttatgctatgcactgggtccgccaGggccccaggcaaggggctagagtgggtggcagttatatcaaatgatggaaattataacgactatgcagactccgtgaaggGggcgattcaccatttccagagacaactccaagaacacgctatttctacaaatgaatagcctgagagttgaggacacggctgtctataactgtgcgagaggaaaggctggccatacccactacggattggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12367 JY8QFUQ01BZU3Z productive (see comment) Homsap IGHV3-48*01 F 1030 97.24 211/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.37.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'TC' (2 nucleotides at position 78 to 79 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 177 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagctGatagcatgaactgggtccgGccaggctccaggggaagggctggagtgggtttTCatgacattantagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12368 JY8QFUQ01B8W6T No results +12369 JY8QFUQ01BLVMS No results +12370 JY8QFUQ01DW7YL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 734 81.65 178/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12371 JY8QFUQ01ABKHV No results +12372 JY8QFUQ01CDYFH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12373 JY8QFUQ01AHFVU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 940 93.06 201/216 nt Homsap IGHJ3*02 F 250 100.0 50/50 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKRLEGVADDAFDIW in-frame + tctggattcacctttagcagctatgccatgggctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtgggagtggtcggagcacatactacgcagactccgtgaagggccggtacaccatctccagagacaattccaagaatacgatgtctgtgcaaatgagcagcctgagagtcgaggacacggccatatattattgtgtgaaaaggttggaaggagtggctgatgatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca +12374 JY8QFUQ01DBVBN No results +12375 JY8QFUQ01DSBEO productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame + ctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +12376 JY8QFUQ01DPT8R productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12377 JY8QFUQ01DTVEM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1011 95.07 212/223 nt 94.17 210/223 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [3.17.37.11] CAKDGARGGGSCFNSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR1-IMGT at codon 26 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 183 in the user submitted sequence), (cause frameshift) tggcagcctGctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12378 JY8QFUQ01AX93I productive Homsap IGHV3-66*02 F 858 89.25 191/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 3 8 7 12 8.7.12 [1.17.38.11] CARQTAPFGYFEDW in-frame + ctcggaattctccgtcagtgacagtcacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtagtgcatattatgcagactccgtgaggggccgattcaccatcgccagagacaaatctaagaacgtgttgtatcttcaaatgaacagtctgagacctgaggacacggctgtgtactactgtgcgagacagactgccccttttgggtactttgaggactggggccagggaatcctgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +12379 JY8QFUQ01A3BLN productive (see comment) Homsap IGHV3-30*01 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 7 8 14 7.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) cctcggattcacctcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12380 JY8QFUQ01BS0FQ unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CARRRGLNYYSFMDVW# out-of-frame + ctctggatacagcttcgccaactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatcgatcctagtgactctgataccagatatagcccgtccttccaaggccaagtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgcaggcctcggacaccgccacgtattactgtgcgagacggcggggccttaactactactcctttatggacgtctgggggccaagggacccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12381 JY8QFUQ01AUM5Q productive (see comment) Homsap IGHV4-4*01 F, or Homsap IGHV4-4*02 F or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 2 9 7 14 9.7.14 [1.17.38.11] CARDKDVTARGTFDMW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagtaattactggtggatttGgggtccgccagtccccaggggaggggctggagtggattggagaagtctatcatactgggaccacctattacaacccgtccctgaagagtcgaatcaccctgtcagtagacaagtccaggaatcagttctccctggagatgacttctgtgaccgccgcggacacggccgtgtatttctgtgcgagagataaagacgtgacagctcgtgggacctttgatatgtggggccaggggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +12382 JY8QFUQ01DJLBK productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccta +12383 JY8QFUQ01BEBN4 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + tctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +12384 JY8QFUQ01CABVX productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 947 92.31 204/221 nt 90.5 200/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtgataatttctactGggggctggatccgccagCcccccagggaaggggActgcagtggattgGggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12385 JY8QFUQ01BGQMX productive (see comment) Homsap IGHV4-39*03 F 893 89.55 197/220 nt 89.09 196/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'TGG' (3 nucleotides at position 72 to 74 in the user submitted sequence), (do not cause frameshift); tctccggtggctccatcaacagtagaaattattattggggctggatccgccagccccccagggaagggtttTGGgagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12386 JY8QFUQ01CSRA0 productive (see comment) Homsap IGHV3-66*02 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-18*01 F 3 8 7 10 8.7.10 [2.16.38.11] CARDRYNSATLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) ggctcaagactaatcgccactagtaactatatgagttgggtccgccaggctccagggaagggctgcagtgggtctcagttatttataacggtggtagaacatactacgcagactccgtgaagggccggttcaccatctccagagacagttccaagaacacggtgcatcttcaaatgaacagcctgagaactgaggacacggctgtgtactactgtgcgagagatcgatacaactctgccacgctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12387 JY8QFUQ01AKD2L productive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'A' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); ctctggattctccAtttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12388 JY8QFUQ01AVLTJ No results +12389 JY8QFUQ01AS6VB unproductive Homsap IGHV3-48*01 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [0.17.38.11] CARAGWELLQG#DYW out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); ctggattcaCcctttagcagtcgtagtatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattgatggtggtagcactaccatattctacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatctgcaaatggacagcctgagagccgacgactcggctacatattactgtgcgagagcgggttgggaattactacaagggatgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12390 JY8QFUQ01BXLCN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 87.56 190/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12391 JY8QFUQ01A9XMX productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1065 97.76 218/223 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 3 8 10 15 8.10.15 [1.17.38.11] CTTFGLTTVTKGYFDFW in-frame + ctctggattcactttcaataacgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaaactgatggtgggacaacagagtacgctgcacccgtgaaaggcagatttaccatctcaagagatgattcaaaaaacacgctttatctgcaaatgaacagcctgaaaatcgaggacacagccgtgtattactgtaccacattcggcctgactacggtgactaaaggctactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12392 JY8QFUQ01A7LR6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 825 86.36 190/220 nt 85.91 189/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [2.17.38.11] CVKDRDFLWGTYRLQLE##W out-of-frame - in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); agcctctggattcatgtttagtgactatTgggatgagctgggtccgccaagttccacaagaggggctggagtgggtcgcaggtatcagtggcagtggtggaagcattaactacgcagactccgtgaagggccgattcaccatttccagagacaattccaagaacactctctatttgcaaatgaccgacctgagagccgacgacacggccgtatattactgtgtgaaggatcgtgacttcctttgggggacttatcgtcttcaacttgaaaaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12393 JY8QFUQ01C44LZ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.37.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 106 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12394 JY8QFUQ01BQ58O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [2.17.38.11] CARDRLTISALDYW in-frame - gcctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12395 JY8QFUQ01C30TT No results +12396 JY8QFUQ01A699S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*02 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDRYPRSTAITAPDYW in-frame + cctctggattcccctttagcaactatgccatgacctgggtccgccaggctccaggggagggactggaatgggtctcaagtattagaggtagtggtgacaggacatcctacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagctgaacaacctgagagccgaggacagggccgaatattactgtgcgaaagatcgctaccctcggtcgacagctattacagcgcctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggctcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12397 JY8QFUQ01CL1G6 No results +12398 JY8QFUQ01DVSSC unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.89 192/216 nt 87.96 190/216 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 7 8 X 7.8.X [1.17.38.11] CAKGTRL*RLVYI#DSW out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaatgggccggagtgggtctcagCcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaagggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12399 JY8QFUQ01AXKC5 unproductive Homsap IGHV3-48*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDRGGSAYPIFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactgggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12400 JY8QFUQ01CO56R No results +12401 JY8QFUQ01BNLQK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtcgacggtgtcgtggcaactc +12402 JY8QFUQ01CA9YP unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1085 100.0 218/218 nt 98.62 215/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [2.16.38.11] CAKDRITIFPTTGST#W out-of-frame - in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcacctttagcagctatgccatgagctgggtccGgccaggctccagggaagggctggagtgggtctcagcGtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatatttcctacaactggttcgacccctggggccaaggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12403 JY8QFUQ01AEF8J productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDPFIAATGRPWYFDNW in-frame + cccctggattcaccttcagtagttatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtgataaatactatgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtttctgcaaatgaacagcctgagaagtgaagacacggctgactattactgtgcgaaagacccatttatagcagcaactggccgcccctggtattttgacaactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12404 JY8QFUQ01AZW8J productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARALIVVAGAPVYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); tctctggattcaccttcagtagttatagtatgatctgggtccgccaggctGccagggaaggggctggagtgggtcgcttcaattagtcataccgggggttccaaatattacggagactcactgaagggccgattcgccatctcaagagacaacgacaagaactcactgtatctgcaaatgaccagcctgagagccgaggacacggctgtctactactgtgcgagagccctaatagtagtggctggtgcccctgtctattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12405 JY8QFUQ01A4L5L unproductive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CATSPFTVTTGKDAY## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggcccagggaaccctggtcctcgtctcctcgagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12406 JY8QFUQ01AY12P No results +12407 JY8QFUQ01BY4NA productive (see comment) Homsap IGHV3-48*03 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [1.17.37.11] CARESWWSGFYGWYDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgagggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12408 JY8QFUQ01AJIEM productive Homsap IGHV3-48*03 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDRADLFYDSSGYQFDLW in-frame - ctctggattcatcttcagcgatcatggaataaactgggtccgccaggctccggggaagggtctggagtggatttcattcgtcagtagtaggggtgggaccatccactacgcagactctgtgaagggccgattcatcatctccagagacaactccaggaacacagtatttctacaactgaacagactgagagacgaagacacggctatttattattgtgcgagagacagggcggatttgttctatgatagcagtggttaccaatttgatctttggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12409 JY8QFUQ01B12IK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + tctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12410 JY8QFUQ01AUNQO unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 7 X 8.7.X [1.17.38.11] CATLRGGY#FDYW out-of-frame - ctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagaggggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12411 JY8QFUQ01BJAW9 productive Homsap IGHV3-7*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + cctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaacctcagg +12412 JY8QFUQ01BZIFS productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 863 88.84 191/215 nt 85.58 184/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-19*01 F 2 8 7 16 8.7.16 [1.17.38.11] CTNDHSMAVSAKHAFDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'AGTGCA' (6 nucleotides at position 24 to 29 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'AC' (2 nucleotides at position 55 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'AC' (2 nucleotides at position 120 to 121 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 71 of V-REGION: 'GT' (2 nucleotides at position 130 to 131 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 34 of V-REGION: 6 nucleotides (from position 21 in the user submitted sequence), (do not cause frameshift) tctctggtgcctccatgagcagtAGTGCAtactactgGgggctgggtccgccagACcccccgggaagggggccggagtggattgggagtgtctactatggtggGgagcacctactacaaACcccgtcccGTccaagagtcgggcctccatttctgtcgacacgtccaggaacgagttctccctgaggctgaactctgtgaccgccacagacacggctatgtattactgcacgaacgaccattcaatggcagtctctgctaagcatgcttttgatgtttggggtccagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12413 JY8QFUQ01C4L01 productive Homsap IGHV4-34*10 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame + tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12414 JY8QFUQ01CRYCJ No results +12415 JY8QFUQ01AXD9U productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12416 JY8QFUQ01A4XSE productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 958 93.98 203/216 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARLPNTIDSW in-frame - Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) tctggatatagttttgccacctactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatgggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccgggtcaccatttcagccgacaagtccctcagtatcgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagactgcctaacactattgactcctggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +12417 JY8QFUQ01CXRN0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggatccaccttcaacaactatgccatgagttgggtccgccaggttccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag +12418 JY8QFUQ01BQ5J2 No results +12419 JY8QFUQ01A6J0H unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 402 88.24 90/102 nt 87.25 89/102 nt 8 8 X 8.8.X [1.16.X.X] null - No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 48 in the user submitted sequence), (do not cause frameshift) gctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggagggggctggagtgggtctcagccattagtggcagtggtagtcggacat +12420 JY8QFUQ01AEZB2 productive Homsap IGHV3-48*01 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaaggggcccatccgtcttccccctggcgccctgntccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc +12421 JY8QFUQ01DSDR2 productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12422 JY8QFUQ01BISS5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 733 82.41 178/216 nt 81.48 176/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 7 8 13 7.8.13 [1.17.38.11] CAKDQYGSPSDFDNW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'GGA' (3 nucleotides at position 82 to 84 in the user submitted sequence), (do not cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) ctcagggttcgttttgagaaatacgccatgagttgggtccgccaggctcccggaaaggggctggagtgggtctcggctattGGAggtgttgatgatgttggcacatactacgcagcctccgtgaagggtcggttcaccatatccagagacgattccagggagattctctatctacaaatgagtaacctgagagtcgacgatacggccgtctattactgtgcgaaagatcaatatgggagcccatccgactttgacaactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt +12423 JY8QFUQ01B6GAR productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 932 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12424 JY8QFUQ01DDI19 productive Homsap IGHV3-7*01 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcacctttagtgactattggatgagctgggtccgccaggctccagggaaggggctagagtgggtggccaacataaatagagatggaagtgagcaacactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaggatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca +12425 JY8QFUQ01C28YZ No results +12426 JY8QFUQ01C18G3 unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +12427 JY8QFUQ01CU9IP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagacccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12428 JY8QFUQ01C0ZKC unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1019 95.93 212/221 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 1 10 7 X 10.7.X [1.17.38.11] CAWGGSG*#YFDYW out-of-frame - stop codons tctctggtggctccatcagcagtactagttactactggggctggatccgccagcccccagggaaggggctggagtggattggtaacattcattctagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcatggggtggttcgggttgaactactttgactactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12429 JY8QFUQ01B3OI5 No results +12430 JY8QFUQ01AK799 No results +12431 JY8QFUQ01AMPES unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 401 77.21 105/136 nt 76.47 104/136 nt 8 6 X 8.6.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (77,21% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) cctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12432 JY8QFUQ01C1MJ4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactca +12433 JY8QFUQ01BTIW5 unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPLGVG#FDNW out-of-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12434 JY8QFUQ01CPW3I productive Homsap IGHV3-48*01 F 1085 100.0 218/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactgggaccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12435 JY8QFUQ01DQTXL productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12436 JY8QFUQ01B8BCF unknown (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 915 90.91 200/220 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12437 JY8QFUQ01BEJ40 unproductive (see comment) Homsap IGHV3-48*04 F 1049 98.17 214/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-3*02 F 1 8 8 15 8.8.15 [1.17.38.11] CARGVVLAL*YLCGDYW in-frame + stop codons cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagaggggtcgtattggcattatgatacctttgcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12438 JY8QFUQ01BOL94 No results +12439 JY8QFUQ01AJ4MI productive Homsap IGHV3-13*01 F 864 90.87 189/208 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-19*01 F 3 7 7 16 7.7.16 [X.17.38.11] CVRRAVGHWQSNWYFDLW in-frame - attcaccttcagtaactacgacatgcactgggtccgccaatctacaggagaaggtctggagtgggtcgcatctattggtgttgctggtaatacaaactttccagactccgtggagggccgattcaccgtctccagggacaatgacaagaactccgtgtatcttcaaatgaacagcctgagacccggggacacggctgtgtattactgtgttagaagggcggtcgggcattggcagagcaattggtatttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12440 JY8QFUQ01ARV43 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12441 JY8QFUQ01AW7FQ productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 912 92.06 197/214 nt 91.59 196/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 7 17 8.7.17 [1.17.38.11] CAKKYHYGSGTYYYHFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'TA' (2 nucleotides at position 82 to 83 in the user submitted sequence), (cause frameshift); ctctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtcgcaactatTAttatagtggcgatagtacatactacgcagattccgtgaggggccggttcaccatctccagagacaattccaagaacactctgcatctgcatatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaaagtatcactatggttcggggacttattattaccacttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccaacccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12442 JY8QFUQ01CVT32 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactc +12443 JY8QFUQ01BZFPU unproductive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +12444 JY8QFUQ01AYLQ4 No results +12445 JY8QFUQ01BDK1E No results +12446 JY8QFUQ01AUYHV unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 402 88.24 90/102 nt 87.25 89/102 nt 8 8 X 8.8.X [1.16.X.X] null - No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 48 in the user submitted sequence), (do not cause frameshift) gctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggagggggctggagtgggtctcagccattagtggcagtggtagtcggacat +12447 JY8QFUQ01CVEEK productive (see comment) Homsap IGHV3-72*01 F 1093 98.67 222/225 nt 98.22 221/225 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-15*01 F 1 8 10 8 8.10.8 [2.17.38.11] CLRPPRYDPW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gcctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaAaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12448 JY8QFUQ01C1OMJ productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12449 JY8QFUQ01C1R2Y productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CTRVGTFNWFGPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggGggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12450 JY8QFUQ01AGDVR productive Homsap IGHV3-30*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CAKDELPWDTIEYYFDYW in-frame + cctctggattcaccttcaatattttttctatgcactgggtccgccaggctccaggcaagggactagagtgggtgtcacttgtttcatatgatggatctaagaaaaagtacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatgagctgccttgggacacaattgaatattattttgactattggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcatcgctgcctggtcagggcttcttccc +12451 JY8QFUQ01DULJJ productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtgcttccccctggcaccctccctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12452 JY8QFUQ01DD9W8 unknown (see comment) Homsap IGHV3-74*03 F 137 52.72 97/184 nt 7 8 X 7.8.X [X.17.29.X] null + No rearrangement found stop codons attcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +12453 JY8QFUQ01BYOYM productive Homsap IGHV3-33*02 F 877 89.81 194/216 nt Homsap IGHJ1*01 F 197 86.54 45/52 nt Homsap IGHD6-6*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDRQDARAEHLQYW in-frame - tctggattcatcttcagtaattatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggctgttctgtggttcaatggaaatacgaagtattatgcagactccgtgaagggccgcttcaccatctccagagacacatccacgaacacgctgtttttgcaaatggacagcctgagagccgaggacacggctgtctattattgtgcaagagatcgtcaggacgcccgcgctgaacatctccaatactggggccagggcaccatggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12454 JY8QFUQ01ACHBJ unproductive Homsap IGHV3-48*03 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD2-8*02 F 3 8 8 X 8.8.X [1.17.38.11] CARESWWSGFI#WYDPW out-of-frame - cctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggctttataggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12455 JY8QFUQ01CAUD4 No results +12456 JY8QFUQ01AM7OF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGHSYYVSSGPDYW in-frame + cctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12457 JY8QFUQ01CXH1Q productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 944 93.49 201/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-13*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARGVGQQLPPLDW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift); tctctcgtgcctccatGcaatatttcctactggagctggatccggcagcccccagggaggggactggagtggattggatatatctatgatagtgggagtaccaactacaAacccctccctcaagagtcgagtcaccatatctatagacacgtccaagaaccagttctccctgaggctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgaggggggtggggcagcaactgccccccttagactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12458 JY8QFUQ01AZVJY unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 949 93.52 202/216 nt 93.06 201/216 nt 8 8 X 8.8.X [1.17.37.X] null - No rearrangement found in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccaggggaaacctgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12459 JY8QFUQ01DI5PB productive Homsap IGHV3-48*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTRQTGNYYYFGVDVW in-frame + ctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +12460 JY8QFUQ01BQAMA No results +12461 JY8QFUQ01CUUWD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12462 JY8QFUQ01B3VPS productive (see comment) Homsap IGHV4-39*07 F 862 87.84 195/222 nt 87.39 194/222 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-3*01 F 3 10 7 18 10.7.18 [2.17.38.11] CARGWAQQAGPTFVGWFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); tctgctggtggctccgtcagaagtaccagttactactGggggctggatccgccagcccccagggaaggggctggagtggattagtaacattcattctagtggaaccacctactacaacccgtccctcaagagtcgagtcaccatttcaatagacacgtccaacagccagttctccctgagcctgaggtctgtgaccgccgcggacacggctatctattactgtgcacgaggttgggcccaacaggcgggacctacgtttgttggctggttcgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12463 JY8QFUQ01CYY27 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [0.17.38.11] CARDNYGDY## out-of-frame - tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12464 JY8QFUQ01BMSOW productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); gcctctggaGttcacctttaccaactatggcatgagctgggtccgccaggctcCcagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12465 JY8QFUQ01BPNQA productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 696 80.84 173/214 nt 80.37 172/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 78 of V-REGION: 'AG' (2 nucleotides at position 135 to 136 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcgaAGtctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +12466 JY8QFUQ01C3JTT productive (see comment) Homsap IGHV3-7*02 F 917 92.09 198/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.16.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 33 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +12467 JY8QFUQ01B8KUQ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 980 95.35 205/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [0.17.38.11] CARDSRHSASGSYSDYW in-frame - ctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12468 JY8QFUQ01DQVLD productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 728 82.33 177/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDWGGSFDRYYFDYW in-frame - Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagataggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12469 JY8QFUQ01BRNQE productive (see comment) Homsap IGHV4-61*02 F 875 88.69 196/221 nt 88.24 195/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); tctctggtggccCccatcagcagcagcacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttccccc +12470 JY8QFUQ01A0FII productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CIMDLVGRADYW in-frame + ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +12471 JY8QFUQ01DHJ30 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1065 97.76 218/223 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 3 8 10 15 8.10.15 [1.17.38.11] CTTFGLTTVTKGYFDFW in-frame + ctctggattcactttcaataacgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaaactgatggtgggacaacagagtacgctgcacccgtgaaaggcagatttaccatctcaagagatgattcaaaaaacacgctttatctgcaaatgaacagcctgaaaatcgaggacacagccgtgtattactgtaccacattcggcctgactacggtgactaaaggctactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +12472 JY8QFUQ01AXKJ1 productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12473 JY8QFUQ01AQ0N2 No results +12474 JY8QFUQ01A7K2I unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 804 85.98 184/214 nt 8 8 X 8.8.X [0.17.38.X] null - No rearrangement found tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12475 JY8QFUQ01B9V2V No results +12476 JY8QFUQ01BB5MK unproductive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPPWCWG#FDNW out-of-frame + stop codons cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactccccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12477 JY8QFUQ01BG4JY productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 728 82.33 177/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDWGGSFDRYYFDYW in-frame + Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggagccagggaatcctggtcactgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +12478 JY8QFUQ01DCSPK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12479 JY8QFUQ01BMWQ1 productive Homsap IGHV3-30*13 F 856 88.13 193/219 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [2.17.38.11] CARGTMLRGVTKARYGLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcaccttcagtcgctatagcatgaactgggtccgccaggttccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12480 JY8QFUQ01BFX1E productive Homsap IGHV3-9*01 F 906 90.45 199/220 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [2.17.38.11] CVRQAYYHDSSAYFFSRYWYFDLW in-frame - agcctctggattcacttttgatgactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacgccaagaagtccctgtttctgcaaattaaaagtctgagagttgaggacacggccttatattattgtgtgaggcaagcgtattaccatgatagcagtgcttacttcttctcccgctactggtacttcgatctctggggccgtggcaccccggtcactgtctcttcagcctccaaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12481 JY8QFUQ01B4Q3C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12482 JY8QFUQ01C18QX No results +12483 JY8QFUQ01AGD1R unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +12484 JY8QFUQ01CGEIG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12485 JY8QFUQ01AO2LB No results +12486 JY8QFUQ01CSM0I productive (see comment) Homsap IGHV3-30*07 F 838 87.21 191/219 nt 86.76 190/219 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [2.17.38.11] CASLGSYESSGPRW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcctcttcagtagttatgctatacactgggtccgccaggctccaggcaaggGggcttgagtgggtggcggttgtttcatatgatggaaataataaattttacgcagactctgtgaagggtcgatttagcctctccagagacaactccaagagcacggttgatctgcaaatggacaacttgagatccgaagacacggctgtatattattgtgcgagcctcggttcctatgagagcagtggtccccgatggggcccgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +12487 JY8QFUQ01CJJYL productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 882 89.86 195/217 nt 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [2.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); gcctctggggttcaccgtcagtagcaaGgttcatgagctgggtccgccaggctccagggaaggGggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12488 JY8QFUQ01BUIDF productive Homsap IGHV3-7*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + cctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctca +12489 JY8QFUQ01DJIQP productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 917 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); tctggaattcagcttcagtacctaGtaacatgaactgggtccgccaggntccagggaaggggctggantgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12490 JY8QFUQ01CF7VI unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 947 94.34 200/212 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD2-21*02 F 3 7 8 X 7.8.X [X.17.38.11] CARDGGHSYGPSFDH## out-of-frame + gatacaccttcaccaggtacattatgcactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcaaccctagaggtgttagcagaagctacgcacagaagttccagggcagagtcaccatgaccaccgacacgtccacgagcacagtctatatggagctaaacagcctgagatctgaggacacggccgtttattactgtgcgagagatggagggcacagctatggaccctcctttgaccactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12491 JY8QFUQ01AY7BL No results +12492 JY8QFUQ01CKVX4 No results +12493 JY8QFUQ01BHGU1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKNVSLWFGDLL#YHFDYW out-of-frame + ctctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtcgcaactattatttatagtggcgatagtacatactacgcagattccgtgaggggccggttcaccatctccagagacaattccaagaacactctgcatctgcatatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaaatgtatcactatggttcggggacttattattaccacttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccaaccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12494 JY8QFUQ01BR56L unknown (see comment) Homsap IGHV3-7*01 F 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ1*01 F (see comment) 23 70.0 7/10 nt 8 8 X 8.8.X [2.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaGgggggtactggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaccataaatcacgatggaagtcaaatttactatatggaccttgtgaagggccggttcaccatctccagagacaacgccgagacctcactctatttgcaaatgaacaccctgagagccgaagacacggctgtctattactgtgcgagggcttcttcc +12495 JY8QFUQ01A0OTP productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.16.38.11] CARAPRTATLLDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccaggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12496 JY8QFUQ01AGW5X No results +12497 JY8QFUQ01APG9M unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 832 87.5 189/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found tctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12498 JY8QFUQ01A7NVO productive (see comment) Homsap IGHV1-3*01 F 912 92.06 197/214 nt 91.12 195/214 nt Homsap IGHJ4*02 F (see comment) 231 97.92 47/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDGEPLGGDYFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 80 of V-REGION: 'G' (1 nucleotides at position 142 to 142 in the user submitted sequence), (cause frameshift); tggatacaccttcacttcttatgctgtaaactgggtgcgccaggcccccggacaAaaggcttgagtggatgggatggatcaacgctggcacgggtaacacaaaatattcacagaagtttcagggcagagtcaccattaccaGgggacacatccgcggacacagtcttcatggagctgagcagtctaagatctgaagacacggctgtgtattattgtgcgagagatggggagccactgggaggcgactactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12499 JY8QFUQ01BWKNJ productive Homsap IGHV4-61*02 F 902 90.05 199/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*02 F 3 10 7 17 10.7.17 [1.17.38.11] CARGVISLSGGNGDWFDPW in-frame + tctctggtgcctccatcagtagtggtaactactattggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatttataccagtgggagcaccaagtacaacccctccctcaaggatcgagtcaccatatcaacagacctgtcccagaaccacttctccctgaagttgaagtcaatgaccgccgcagactcggccgtgtattactgtgcgcgaggagtgatctctttatctggcggtaacggtgactggttcgacccctggggccagggaacccgggtcatcgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttc +12500 JY8QFUQ01CAH26 productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12501 JY8QFUQ01AK776 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 995 93.39 212/227 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 10 9 19 10.9.19 [1.17.38.11] CARGSSRGGNSDGVYYELDYW in-frame - tctccggggacagtgtctctaccacccgtgctgcttggaactggatcaggcagtccccatcgggaggccttgagtggctgggaaggacatactacaggtccaagtggcttaatgattatgcagtgtctgtgaaaagtcgaattaccatcaatccagacacatccaagaaccagttttccctgcagttgaaatctgtcattcccgaggacacggctgtttattactgtgcaagaggttccagtcgcggggggaattctgatggggtctactatgaacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +12502 JY8QFUQ01CNW7H productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 932 92.2 201/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaGggggctggtgtgggtctcacgtactaataCcgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattattgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +12503 JY8QFUQ01CVOQV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 747 82.49 179/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] WCESPPTQWFSHPSTL#FDIW out-of-frame + Low V-REGION identity (82,49% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacttttagctcttttaccatgagctgggtccgccagactccggggaagggcctggaatgggtctctgctatcagtggcagcgatgatcgcacatcttatgttgactccgtgaagggccgcttcaccatctccagagacacttccaggaatacactgtttctgcagatgaacagcctgagcgccgaagatacggccacatacttttggtgtgagagtcccccaactcagtggttttcccacccttccacactcactttgacatctggggccagggaaccgtggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12504 JY8QFUQ01BP1SF No results +12505 JY8QFUQ01C57SN productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 815 86.24 188/218 nt 85.32 186/218 nt Homsap IGHJ6*02 F 187 79.66 47/59 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARRDSDFRMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'A' (1 nucleotides at position 174 to 174 in the user submitted sequence), (cause frameshift); tgtctggatatgactttagcagattttggatcgcctgggtgcgccagatgcccgggaAaaggcctggagtggattggaatcatctatcctagtgactctgatacgagatacagtcccaccttccaaggccaggtcattatctcagccgacaagtccctcagtaccgcctacctAttttttgagcagtctgagggcctcggacaccgccatgtatttttgtgcgagacgtgattccgacttccgtatggacgtctggggccaggggaccacggtcaccgtgtctccaacatcccccggaccagcccccgaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +12506 JY8QFUQ01DOJQ3 No results +12507 JY8QFUQ01DA2RM unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 858 89.25 191/214 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [0.17.38.11] CARLGQLALDY## out-of-frame + gggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactgggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12508 JY8QFUQ01CYTAI productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 705 81.31 174/214 nt 79.91 171/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,31% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatgggcCtgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgGcagactccgtgaGgggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggagctcag +12509 JY8QFUQ01DMWE4 productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaTggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12510 JY8QFUQ01C9RMH productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12511 JY8QFUQ01BSW14 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 901 90.41 198/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [2.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) gtgttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagccCcgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgattttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12512 JY8QFUQ01BN1FJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [2.17.38.11] CARDRLTISALDYW in-frame - gcctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12513 JY8QFUQ01AU8X4 productive (see comment) Homsap IGHV4-61*04 F 945 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD2-15*01 F 3 10 7 18 10.7.18 [2.16.38.11] CARERRVAATASRAFGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 46 of V-REGION: 2 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) gtctctggtggctccgtcagcagtgctagtcactactggagctggatccgccagccccagggagggactggagtggattggatatatccttaacagtgggagcaccaacaacaacccctccctcaagagtcgagtcaccatatcagtggacgcgtccaagaaccaattcttcctgaagctgagctctgtgaccgctgctgacacggccttatattactgtgcgagagagagacgggtggcagccactgctagtcgggccttcggtatggacgtctggggccaagggaccacggtcaccgtctcctcggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12514 JY8QFUQ01AZN8E No results +12515 JY8QFUQ01CJXFO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ1*01 F 89 63.46 33/52 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcttccccgaaccggtcgacggtgtcgtggcaactcag +12516 JY8QFUQ01BNS72 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 890 90.7 195/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD5-18*01 F 3 10 7 17 10.7.17 [1.17.38.11] CAGEQMIDAVSHNYAMDVW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01BNS72 ; 8 AA in Homsap_IGHV4-59*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggctccatcagcatcaatacttacttctggagttggatccggcagcccccagggaagggactggagtggattgggtatatctctcacagtgggagtgccaactacaacccctccctcgagagtcgagtcaccatcttaagagacacgtccaagaaccagttctctctgaggctgagggctgtaaccgcggcggacacggccgtgtatttctgtgcgggggaacagatgattgacgcagtctcccacaactatgccatggacgtctggggccaagggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +12517 JY8QFUQ01C3JXN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12518 JY8QFUQ01AJ597 unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12519 JY8QFUQ01B8AC6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [2.17.38.11] CVRYDYSRLHRSNYFGPW in-frame - gtctctggattcaccttcatcagttatggcatgagttgggtccgccagtttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +12520 JY8QFUQ01APK2R unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPLGVG#FDNW out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); cctctggattGcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttggggttttgacaactggggccagggaaccctggtcaccgtctcctcagccttcaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12521 JY8QFUQ01BNGQY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame - cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12522 JY8QFUQ01CN4QR No results +12523 JY8QFUQ01CCPYX productive Homsap IGHV1-69*02 F 813 86.92 186/214 nt Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [0.17.38.11] CATDHPRGRQSVYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tggggccaccttcaacagttatactttcagctgggtgcgacaggcccctggacaagggcttgagtggatgggaatgatcatctccacccttggtgtgacaaactacgcgcagaggttccagggcagagtcacgatctccgcggacaagtccacgacgacagcctacatggagttgacaaggctgacatttgaagacacggccgtttattattgtgcgacagatcatccccgcgggcgtcagtccgtgtactggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +12524 JY8QFUQ01CXOY1 No results +12525 JY8QFUQ01CTNGN No results +12526 JY8QFUQ01B9VAA productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 826 87.79 187/213 nt 85.92 183/213 nt Homsap IGHJ1*01 F 134 73.08 38/52 nt Homsap IGHD3-16*01 F 3 8 7 15 8.7.15 [1.17.37.11] CARDGDFWELPGVLPIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 104 of V-REGION: 'T' (1 nucleotides at position 212 to 212 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 77 of V-REGION: 1 nucleotides (from position 134 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 82 of V-REGION: 1 nucleotides (from position 148 in the user submitted sequence), (cause frameshift) gctctggattcacctttaatagctttgccatgagctgggtccgccaggctccagggaaggggccggagtgggtcgcattcattagtcgtaacagtcacataagctacgcggactcagtgaggggccgattcacatcgccatggacaatccaagaactcactgcttctgcaaatgaacagcctgagagccgaagacacggctgtctattactTgtgcgagagatggtgatttttgggagctaccaggagttcttccaatatggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12527 JY8QFUQ01CYJKV productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 993 96.26 206/214 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARADNYDSLGLKFDPW in-frame + ctctggtgactccatcagtagtaactactggaactggatccggcagcccccagggaagggactggagtggattgggtatatctatcacagtgggagcaccagctacaacccctccctcaggagtcgagtcaccatatcattagacacgtccaagaaccagttctccctgaaactgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggcggataattatgatagtcttgggctgaagttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +12528 JY8QFUQ01CFMT5 productive Homsap IGHV3-48*01 F 1080 99.54 216/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASIFGVVPLGNYYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca +12529 JY8QFUQ01CTPPL unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 832 87.5 189/216 nt 87.04 188/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found in FR2-IMGT at codon 48 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggaCgggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgagacgtcag +12530 JY8QFUQ01AC7WH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - ctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12531 JY8QFUQ01AH4E3 productive (see comment) Homsap IGHV3-7*01 F 923 92.45 196/212 nt 91.04 193/212 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [0.16.38.11] CVRDRFYDSSGYEFGELGDYSDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) ctggattcacatttagtaactactggatgagctggtccgccaggntccaggaaggggctggantggtggccaacntaaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctgtgtgagagatcgattttatgatagtagtggttatgagtttggggaattgggggactactctgaccactggggccagggaacccaggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12532 JY8QFUQ01DHLIE productive (see comment) Homsap IGHV4-4*07 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt 8 7 9 8.7.9 [1.17.38.11] CARGDWYFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CA' (2 nucleotides at position 15 to 16 in the user submitted sequence), (cause frameshift); tctctggtggctccCAtccattaatcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtagtcataccagtggaagcaccaggtacaacccctccctcaagagtcgagtcaccgtgtcagcagacacgtccaagaaccagttctccctgaagcttagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggagactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12533 JY8QFUQ01B0G04 unknown (see comment) Homsap IGHV4-61*02 F 888 89.55 197/220 nt 89.09 196/220 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatTttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12534 JY8QFUQ01CTZ8E productive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12535 JY8QFUQ01AMPJP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaattttaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12536 JY8QFUQ01C67XX productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 940 93.06 201/216 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 7 10 9.7.10 [1.17.38.11] CASHGGKYFPQW in-frame + tctggtggctccatcagcagtagtaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggacaaatccatcatggtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12537 JY8QFUQ01BWVGJ No results +12538 JY8QFUQ01A33F5 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctgagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12539 JY8QFUQ01CSWQD productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDPRSVSRYSLFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtgactattggatgagctgggtccgccaggctccagggaaggggctagagtgggtggccaacataaatagagatggaagtgagcaacactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacatggctatgtatttttgtgcgagagatcctcgttccgtgagcaggtactctttatttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12540 JY8QFUQ01CIBDC productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12541 JY8QFUQ01DDBFR productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 950 93.12 203/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +12542 JY8QFUQ01CLSH1 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagcaaccataacatgaactgggtccGgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12543 JY8QFUQ01DLL36 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 916 90.54 201/222 nt 90.09 200/222 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD5-18*01 F 3 8 10 X 8.10.X [1.16.38.11] CTTAPSETYATEYFAMDV# out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtaatgtttggatgaattgggtccgtcaggctccagggaagggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccagggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12544 JY8QFUQ01DM31P unproductive Homsap IGHV3-48*02 F 971 94.88 204/215 nt 93.95 202/215 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [0.17.38.11] CARPAGEGDPFF##YYSGLDVW out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaTggggctggagtggatttcatacattagtggtagtggcggtGaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12545 JY8QFUQ01BSZ1W productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgctggtccagggcttcttcccccaggag +12546 JY8QFUQ01A3WPZ productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1004 95.87 209/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +12547 JY8QFUQ01DPW3O No results +12548 JY8QFUQ01CULSO productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + ttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +12549 JY8QFUQ01CUXO1 productive Homsap IGHV3-11*01 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - gcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12550 JY8QFUQ01DK3GO productive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*11 F or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 831 87.85 188/214 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 17 8.8.17 [0.17.38.11] CASDREDTAMITAESFNIW in-frame - tggaggcaccttcagtagacatgctatcaactgggtgcgacaggcccctggacaagggcttgagtggatgggagggatcaccccactccttcatacaaccaaatatgcacagaggttccagggcagagtcacatttaccgcggacgaatccacggccacagtctacatgcaactgagcagcctgggatctgaagacacggccgtctattattgtgcgagcgatcgggaagatacagctatgattaccgcggagagttttaatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12551 JY8QFUQ01A3EIJ No results +12552 JY8QFUQ01C58KO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +12553 JY8QFUQ01CH5WU productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F 335 88.37 76/86 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 X X 10 X.X.10 [X.X.28.11] CARLGQLALDYW in-frame - tcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12554 JY8QFUQ01DP7SJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-19*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDPQQLLAEVNWFDPW in-frame + ctctggattcacctttcgcagctatgccatgagttgggtccgccaggctccaggaaggggactagagtgggtctcgtctataagtggtagtggtgataaaacaaagtatgcagactccgtgaagggccggttcaccatctcccgagacaatgccaggaacactttttatctgcaaatgaacagcctcagagccggggacacggccgtctattactgtgcgaaagatcctcagcagttattggcagaagtaaactggttcgacccttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctccgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12555 JY8QFUQ01BNY5Q No results +12556 JY8QFUQ01C18IM productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*03 F 886 90.28 195/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 8 7 13 8.7.13 [2.17.38.11] CVREVTGVWDWFDPW in-frame - gcctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactctgtgaagggccagttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12557 JY8QFUQ01B7DGU productive (see comment) Homsap IGHV4-39*03 F 929 91.36 201/220 nt 90.91 200/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcCccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12558 JY8QFUQ01B199R productive Homsap IGHV3-49*04 F 1048 96.44 217/225 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 3 8 10 12 8.10.12 [2.17.38.11] CTKCSVTIYFFDYW in-frame - gcctctggattcaccttcagtagctatgctatgcactgggtccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12559 JY8QFUQ01CDN1K unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 860 88.53 193/218 nt Homsap IGHJ1*01 F 152 76.92 40/52 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [1.17.38.11] CTRVGTFNWF#PW out-of-frame - cctctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12560 JY8QFUQ01BZPI8 No results +12561 JY8QFUQ01AXNMX No results +12562 JY8QFUQ01AOFRF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [2.17.38.11] CATSRGSANWYPFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggGggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12563 JY8QFUQ01BDHEG productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 869 88.99 194/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ggcctcctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12564 JY8QFUQ01B5ZUI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + tctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12565 JY8QFUQ01B7DZ7 productive Homsap IGHV3-33*03 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARSDLSMVRDLDYW in-frame - cgtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatgatttggtatgatggaagccttacatattatgaagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgctgtttctgcaaatgaatagcctgagagtcgaggacacggctctgtattactgtgcgagatccgacctctctatggttagagatcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12566 JY8QFUQ01AT5TS productive Homsap IGHV1-24*01 F 993 96.26 206/214 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [0.17.38.11] CAIGAMATW in-frame - cggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagtatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12567 JY8QFUQ01BNLPI productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.35 193/216 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 7 8 14 7.8.14 [1.16.38.11] CARVIPGRGNYAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) cctctggattcgactttggtattattggatgagttgggtccgccaggctccagggaagggactggagtggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12568 JY8QFUQ01C4SDR productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 500 80.65 125/155 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 X 7 9 X.7.9 [X.6.38.11] CARLDGHFDLW in-frame + Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcgcctcatcatctccagagacgaatccaagagtgagctgtatcttcggatgacgaaagtgaaagccgaagacgcggccgtatattactgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12569 JY8QFUQ01AOQJV productive (see comment) Homsap IGHV3-7*01 F 926 92.56 199/215 nt 92.09 198/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 7 8 15 7.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) tctacattcacgtttagtcggtatggatgagctggtaccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12570 JY8QFUQ01B1N1T productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt 84.79 184/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDPGNYWGYYYDSW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); gtctggattcacctttagtgattatgcCcttgagctgggtccgccagactcccgggaAaggggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgagagatccgggaaattattggggatactattatgactcttggggcctgggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12571 JY8QFUQ01AY44B productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12572 JY8QFUQ01BDSWE No results +12573 JY8QFUQ01AGTKI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcgtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12574 JY8QFUQ01BCLBD unproductive (see comment) Homsap IGHV3-7*01 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ4*03 F (see comment) 123 72.92 35/48 nt Homsap IGHD3-16*01 F 1 8 8 X 8.8.X [0.17.38.11] CARVIPGRGNYAF*CL# out-of-frame - stop codons Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 201 to 201 in the user submitted sequence), (cause frameshift); ctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacgGgctgtgtattactgtgcgagagttattcccggccggggaaactatgctttttgatgtctgggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggttcagggcttcttccccca +12575 JY8QFUQ01CZA6T unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +12576 JY8QFUQ01B26V1 No results +12577 JY8QFUQ01CUYP4 productive (see comment) Homsap IGHV1-3*01 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARGRYDISGRGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); tggatacaccttcactagttTttagtatacattgggtgcgccaggcccccggacagaggcttgagtggatgggatggatcaacgcaggcaacggtcacacaaaatattcacagaagttccaggacagagtcaccattataagggacacatccgcgagcacagcctacatggacctgagcaccctgagatctgaagacacggctgtctattactgtgcgagagggcgctatgatattagtggtcgtggccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaagggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +12578 JY8QFUQ01DD5SJ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*01 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [1.17.38.11] CVRDRDFLWGSYRLQLEYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'CA' (2 nucleotides at position 53 to 54 in the user submitted sequence), (cause frameshift); gctctggattcagatttagcagctatggcatgagctgggtccgccaggctccCAaaaaaaggggctggagtgggtctcaggaattagtgcgaatggtggtagtataaattatgcagactccgtgaagggccgattcatcatctccagagacaattccaagaacacattgtttctgcaaatgaatagcctgagagccgaagacacggccgtatattactgtgtgagagatcgcgatttcctgtgggggagttatcgtcttcaacttgaatattggggccaaggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +12579 JY8QFUQ01ACN1F unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 993 96.26 206/214 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 1 8 7 X 8.7.X [1.17.38.11] CARADNYDSLGLKFDP# out-of-frame + ctctggtgactccatcagtagtaactactggaactggatccggcagcccccagggaagggactggagtggattgggtatatctatcacagtgggagcaccagctacaacccctccctcaggagtcgagtcaccatatcattagacacgtccaagaaccagttctccctgaaactgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggcggataattatgatagtcttgggctgaagttcgacccctgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +12580 JY8QFUQ01B3PPT No results +12581 JY8QFUQ01CM85M productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactca +12582 JY8QFUQ01C68HQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDREDSSGYYFFRDGFDIW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctccggtattgGgtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagatcgtgaagatagtagtggttattacttcttccgtgatggttttgatatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggacgtggtcatcgcctgcctggtccagggcttcttccccca +12583 JY8QFUQ01DEDQS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 711 81.11 176/217 nt 80.18 174/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD2-21*01 F 3 8 7 11 8.7.11 [2.17.38.11] CARHLMVYALDVW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DEDQS ; 8 AA in Homsap_IGHV3-23*01), and low V-REGION identity (81,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); agcctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggcaaGggggctggagtgggtctcagtcttatttagtactggcactgcatactacgcagactccgtgaAaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +12584 JY8QFUQ01DMSS9 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12585 JY8QFUQ01BIHKO unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 447 93.14 95/102 nt 8 7 X 8.7.X [1.17.X.X] null - No rearrangement found cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgaca +12586 JY8QFUQ01AZMAF productive (see comment) Homsap IGHV4-39*03 F 928 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 9 7 17 9.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) ctccggtggctccatcaacagtagaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12587 JY8QFUQ01AINHD productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12588 JY8QFUQ01BARB3 productive Homsap IGHV3-30*07 F, or Homsap IGHV3-30*16 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [0.17.38.11] CARDSVPRASEAAYYFDSW in-frame - tggatacagcttcactaatcacattatccattgggtgcgccaggccccaggcaaggggctagagtgggtggcagttatatcacatgatggaactaataaatattactcagactccgtgaagggccgattcaccatctccagagacaattccaagagcgcgctgtatctgcagctgaacgtcctgagcgccgaggacacgagtgtctatttctgtgcgagagattccgtacctcgggcgtcagaggctgcctactactttgactcttggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12589 JY8QFUQ01AMUT4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagAccctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12590 JY8QFUQ01DDUL2 productive Homsap IGHV3-64*02 F (see comment) 784 84.47 185/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-9*01 F 2 8 8 16 8.8.16 [2.17.38.11] CVRGRPMAGFHGILYDNW in-frame - Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggatttagtatcagtaattatggtattcactgggtccgccaggctccagggaggggactggaacttgtttcagctattaccaacaatgcgcatagtgtagtctatgtagactctgtgaagggcagattcatcatctccagagactattccaagaacacgttgtatcttcaaatgggcagactgagaccagaagacacggctgtgtactactgtgtcagagggcggcctatggctggctttcatggaatcctttatgacaactggggcctgggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12591 JY8QFUQ01ABDGN No results +12592 JY8QFUQ01DI2QI unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARKRVPGGNFLM#DYW out-of-frame + cgtctggattcaacttcaatagttttggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggaactttttgatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12593 JY8QFUQ01BG4R5 unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 136 55.47 76/137 nt 10 9 X 10.9.X [1.17.8.X] null + No rearrangement found stop codons ctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +12594 JY8QFUQ01CK2EG productive (see comment) Homsap IGHV3-7*01 F 959 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); gcctctacattcacgGtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacntaaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12595 JY8QFUQ01DGJUU productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatCgggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttcccctggcgccctgctctaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12596 JY8QFUQ01ALOE8 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 167 94.59 35/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcaccttcagtcgttatagcatgaactgg +12597 JY8QFUQ01BIPTQ No results +12598 JY8QFUQ01A5322 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 847 87.67 192/219 nt 87.21 191/219 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 8 21 8.8.21 [2.17.38.11] CARVMREHYYGAGNYPWGGMEVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); gcctctggattcacAttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaatcacgaaaacaccctgtatctggaaatgagtagcctgagagccgaggacgcggccgtctattactgtgcgagagtgatgagggaacattattatggagcggggaattatccctgggggggaatggaagtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12599 JY8QFUQ01BAJOS unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12600 JY8QFUQ01A5EZ5 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12601 JY8QFUQ01BUH5X No results +12602 JY8QFUQ01AN3YW No results +12603 JY8QFUQ01C045Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKEGPTLLTRPPLNW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaacttttggtggtagtggtggttctacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctatatcttcaaatgagcagcctgagagccgaggacacggccatatacttctgtgcgaaagaaggacctacgcttctaactcgcccccctctcaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12604 JY8QFUQ01A48ML No results +12605 JY8QFUQ01DBWQD productive Homsap IGHV3-11*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12606 JY8QFUQ01ABWLU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12607 JY8QFUQ01CZIAW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 160 80.0 40/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgaccttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +12608 JY8QFUQ01BTTE3 No results +12609 JY8QFUQ01DQWJW productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 804 86.05 185/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame - tntctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12610 JY8QFUQ01AFROA unproductive Homsap IGHV1-2*02 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [0.17.38.11] CARGGRRGNYYWGI#DSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); tggatacacgttcaccgactactatgtccactgggtgcgacaggcccctggacaagggcttgagtggatggcgtggatcaaccctaacattggtgtcaccaagtctgcacGaaaaatttcagggcagggtcaccatgaccagggacacgtccatcagcacagccttcatggagctgagcagcctgagatctgacgacacggccgtttattactgtgcgagaggggggcgacgtgggaactattattggggaatcttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12611 JY8QFUQ01BZYY1 unproductive (see comment) Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKEEF*HWLDTTG##W out-of-frame + stop codons ctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaattttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12612 JY8QFUQ01AVUCF unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P 157 57.46 77/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons tctggattcatcttcagtgactactacatgacctggatccgccaggccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12613 JY8QFUQ01CH338 productive (see comment) Homsap IGHV3-64*02 F 967 94.44 204/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 7 8 10 7.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctctggattcatttcagtacttatcctatgcactgggtccgccaggctccagggaaggGgactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12614 JY8QFUQ01CNAQL No results +12615 JY8QFUQ01B0630 No results +12616 JY8QFUQ01DVS1K productive (see comment) Homsap IGHV1-18*01 F 1002 96.73 207/214 nt 96.26 206/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [0.17.38.11] CARNIVGAPFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'GGG' (3 nucleotides at position 44 to 46 in the user submitted sequence), (do not cause frameshift); tggttacacctttaccagctatggtatcagctgggtgcgacaaGGGccccctggacacgggcttgagtggatgggatggatcagcgcttacaatggtaacacaaagtatgcacagaagctccaggacagagtcaccatgaccacagacacatccacgagcacagcctatatggagctgaggagcctgagatctgacgacacggccgtttattactgtgcgaggaatatagtgggagctccttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12617 JY8QFUQ01BHY7V unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 387 76.3 103/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (76,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +12618 JY8QFUQ01B1EO9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 810 86.18 187/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcacgtttagagactattggatgagttgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +12619 JY8QFUQ01CXO19 No results +12620 JY8QFUQ01BFFC2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +12621 JY8QFUQ01CSKA2 productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12622 JY8QFUQ01ATM5X productive (see comment) Homsap IGHV3-11*01 F 795 85.98 184/214 nt 84.58 181/214 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD5-12*01 F 2 8 8 14 8.8.14 [1.16.38.11] CARDRRPWSFDAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 63 in the user submitted sequence), (cause frameshift) tctggattcaccttcagGggactactatatgagttggattcgcctggcactgggaaggggctgagtgggtttcatatattagtggtaatgtgtttaccaaacactacgcagactctgtgcagggccgattcaccatctccagggacaacgacaataagacagtctatctacagatggacaacctgagagccgcagacacggccatgtattactgtgcgagagacaggcgcccatggtcttttgatgcttttgatgtctggggccgggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12623 JY8QFUQ01A95OK No results +12624 JY8QFUQ01B3M1E unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 387 76.3 103/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (76,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +12625 JY8QFUQ01CVGS4 No results +12626 JY8QFUQ01BKNOD productive (see comment) Homsap IGHV1-3*01 F 816 87.68 185/211 nt 86.26 182/211 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [0.16.37.11] CVRGRSPPGDWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 42 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 99 in the user submitted sequence), (cause frameshift) tggatacaccttcactaattatgctctgcaatgggtgcgccgggccccggacaaactttgagtggctgggatggatcaactctgccaatggcaacacaaatattctcagaagtttcagggcagagtcgccattaccagggacacatccgcgaggacaacttacatggaattgagcagtctgacatctgaagacacggcgacatattattgtgtgagaggaagaagtccgcccggcgactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12627 JY8QFUQ01BLJYE productive (see comment) Homsap IGHV3-11*01 F (see comment) 765 83.87 182/217 nt 83.41 181/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARVRCSGNTCGAFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); ctctggattcagcttaagtgactactacatgacctgggtccgccaggccccagggaagggactggagtggctcgcctacattagtcgaactgatgattccgtatattccgcagagtctgtggtgggccgattcaccgtctccagggacaacgtccaaaactcactgTtttttgcagatgattggcctgagagacgaggacacggccgtatattactgtgcgagagtccgctgtagtggtaatacctgcggggcttttgatttgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12628 JY8QFUQ01DCXPQ unproductive Homsap IGHV3-74*03 F 1031 97.25 212/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD2-8*01 F 1 8 8 X 8.8.X [1.17.38.11] CATGPDYAYAM## out-of-frame + cctctggattcaccttcagtcgctactggatgcactgggtccgccaagctccagggaagggcctggtgtgggtctcacgtattaaaagtgatgggattagcacaacgtacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtactactgtgcaaccgggcccgattatgcgtatgctatgtgggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12629 JY8QFUQ01CFBAE No results +12630 JY8QFUQ01A5EG9 unproductive (see comment) Homsap IGHV4-61*02 F 956 92.76 205/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 3 10 7 X 10.7.X [1.17.38.11] CAREPQSNAL#YYFDHW out-of-frame + stop codons tctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgccctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12631 JY8QFUQ01BPDKM productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12632 JY8QFUQ01BED3K No results +12633 JY8QFUQ01CHRAU unknown (see comment) Homsap IGHV3-7*02 F 99 58.02 47/81 nt 8 1 X 8.1.X [0.17.X.X] null - No rearrangement found ctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12634 JY8QFUQ01CM18U productive Homsap IGHV1-3*01 F 871 90.14 192/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [X.17.38.11] CARDGYRSGNGADYW in-frame + ggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12635 JY8QFUQ01C884V No results +12636 JY8QFUQ01DDY3L productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 823 87.04 188/216 nt 86.11 186/216 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.16.38.11] CARDSGSSEYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctgggattcagcttaagttcttatGggcatgaactgggtccgccaggctccaggggggggctggagtgggtctcattcattaacagtattagtagttataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12637 JY8QFUQ01ARPRY productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactc +12638 JY8QFUQ01AYMEF No results +12639 JY8QFUQ01BL1H2 productive (see comment) Homsap IGHV3-7*01 F 968 94.04 205/218 nt 92.66 202/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [2.16.38.11] CATSPSDFDRRWGYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 28 of V-REGION: 'AT' (2 nucleotides at position 10 to 11 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 32 in the user submitted sequence), (cause frameshift) gcctctggaATttaacctttagaaccttttggagagctgggtccgccaggctccagggagggggctggagtgggtggccaacataaAagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12640 JY8QFUQ01DM9RK No results +12641 JY8QFUQ01C0B16 productive (see comment) Homsap IGHV4-61*01 F (see comment) 776 83.71 185/221 nt 82.81 183/221 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'C' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagTccccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccCatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtccaaggactacttccccgaaccggtgacggtgtcgtggaactc +12642 JY8QFUQ01BQ8FU productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 962 94.42 203/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [0.17.38.11] CAGHLLGDPFDYW in-frame + ctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag +12643 JY8QFUQ01CWZQ1 productive (see comment) Homsap IGHV3-7*01 F 926 92.56 199/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD2-21*02 F 2 7 8 18 7.8.18 [1.17.38.11] CSRHGGYTRLYNQNVYLDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 23 in the user submitted sequence), (cause frameshift) tctggattcacatttagcaactttggatgagctgggtccgccagactccagggCaaggggctggagtgggtggccaaaataaacccagacggaagtgagaaatactatgtggactctgtgaagggccgattcaccacctccagagacaactctagaaactcgctgtgtctgcaaatggacagcctgagagccgaggacacggctgtgtattactgttcgagacatggaggttacacgagactctacaatcaaaatgtctaccttgactactggggccagggagcctggtttccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +12644 JY8QFUQ01B8FO0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 721 81.28 178/219 nt 80.82 177/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [2.17.38.11] CAKDQYGSPSDFDNW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'GGA' (3 nucleotides at position 85 to 87 in the user submitted sequence), (do not cause frameshift); acctcagggttcgtttttgagaaatacgccatgagttgggtccgccaggctcccggaaaggggctggagtgggtctcggctattGGAggtgttgatgatgttggcacatactacgcagcctccgtgaagggtcggttcaccatatccagagacgattccagggagattctctatctacaaatgagtaacctgagagtcgacgatacggccgtctattactgtgcgaaagatcaatatgggagcccatccgactttgacaactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12645 JY8QFUQ01A9ABS unproductive (see comment) Homsap IGHV3-48*01 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 133 74.0 37/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARAPF*LL# out-of-frame + stop codons ctctggattcatctttagtagctatagtatgaactgggtccgccaggctccagggaaggggccggagtgggtttcatacattagcggtagtagtagctccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcagatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagcccccttttgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +12646 JY8QFUQ01B2IQ1 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [1.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) gttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12647 JY8QFUQ01DL5VS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +12648 JY8QFUQ01C09W0 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaCcctttggttattatggcatggactgggtccgccaagctccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12649 JY8QFUQ01A01KX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtntcgtgggaactcag +12650 JY8QFUQ01DJA9X productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYYYHFDYW in-frame + gtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaaaagtatcactatggttcggggacttattattaccacttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +12651 JY8QFUQ01CEQK9 unproductive Homsap IGHV3-7*01 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CSRDGRRAT#LDSW out-of-frame + cctctggattcacctttagcagacattggatgacctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtcagagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggagggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga +12652 JY8QFUQ01DLMYL productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 848 89.15 189/212 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [X.17.38.11] CARLGQLALDYW in-frame - cggatcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12653 JY8QFUQ01CR261 No results +12654 JY8QFUQ01BNBTY productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKEQEPHGHYVGTDYW in-frame + gtctggattcaccttcagtagctacggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggccgtgtattcctgtgcgaaagaacaagaaccacatgggcattatgttggaactgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12655 JY8QFUQ01AFTSH productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDYFDSW in-frame + tggatacaccttcaccgactacttcatacactggctgcgacaggcccctggacaacgacttgagtggatgggatggatcaaccctaagaatggtgacacaaagtatgcacagaactttcagggccgggtcaccatgaccagggacacgtccgtcagcaccatatatgtggaggtgagcagcctggaatctgacgacgcagccacttattactgtgcgagaggcttttatggtgactactttgactcctggggccagggagccgtggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +12656 JY8QFUQ01CHEHR productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12657 JY8QFUQ01A9JAF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 841 87.96 190/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CIMDLVGRADYW in-frame + tctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12658 JY8QFUQ01AJ7NL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12659 JY8QFUQ01CM2BA productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 725 81.65 178/218 nt 81.19 177/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDQYGSPSDFDNW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'GGA' (3 nucleotides at position 84 to 86 in the user submitted sequence), (do not cause frameshift); cctcagggttcgtttttgagaaatacgccatgagttgggtccgccaggctcccggaaaggggctggagtgggtctcggctattGGAggtgttgatgatgttggcacatactacgcagcctccgtgaagggtcggttcaccatatccagagacgattccagggagattctctatctacaaatgagtaacctgagagtcgacgatacggccgtctattactgtgcgaaagatcaatatgggagcccatccgactttgacaactggggccagggagccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +12660 JY8QFUQ01CVG4H unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ4*03 F 123 72.92 35/48 nt Homsap IGHD6-13*01 F 3 8 7 X 8.7.X [1.17.38.11] CARPTYSSGRDAF*YL# out-of-frame + stop codons in FR3-IMGT at codon 82 of V-REGION: 'C' (1 nucleotides at position 147 to 147 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacCacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgctttttgatacctgggggccaagggacgacggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12661 JY8QFUQ01BP7Y0 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt 90.95 201/221 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtGataatttcctactggggctggatccgccagcccccagggaagggactgcagtggaCttgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcttggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12662 JY8QFUQ01BLV23 productive Homsap IGHV3-7*01 F 932 92.2 201/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + cctctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga +12663 JY8QFUQ01CEEZ2 productive Homsap IGHV4-39*03 F 924 91.32 200/219 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - ctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12664 JY8QFUQ01BW75G No results +12665 JY8QFUQ01B7XRE unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 435 76.67 115/150 nt 8 7 X 8.7.X [1.17.16.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01B7XRE ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (76,67% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactacttccccgaaccggtgacggtgtcgtggaactcag +12666 JY8QFUQ01AK7YT productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*02 F or Homsap IGHV3-33*06 F 909 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD3-3*01 F 3 8 8 22 8.8.22 [1.17.38.11] CARDFLAPNRFGVFDYYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); gtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaggggtctggaatggttggcaatgatatggtatgatggaaataAaaaaatactacgcagactccgcgacgggccgattcaccatctccagagacaattctgagtacacgctgtctcttcaaatgaacagcctgagagtcgaggacacggctgtctattactgtgcgagggatttcttagccccgaatcgttttggagtgtttgactactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12667 JY8QFUQ01A3KGM productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-22*01 F 2 8 8 21 8.8.21 [1.17.38.11] CARDGGHHEDDGYYNFYYALDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cgtctggattcagcttcaatagatatggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcagtaatttggtatgatggaaaaaacaaatattatgcagactccgtgaagGggccgattcgccatctccaaagacaattccaagaatacggtggatttggagctgaacagtttgagagtcgaagacacggctgtttattactgtgcgagagatggaggccaccatgaagacgatggttattacaacttctactatgctttggacgtttggggccaagggaccacggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12668 JY8QFUQ01A481A unknown (see comment) Homsap IGHV3-38-3*01 ORF 100 53.12 68/128 nt 8 7 X 8.7.X [0.17.11.X] null - No rearrangement found stop codons tggattctccgtcagtttcaactacatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12669 JY8QFUQ01ALMXP productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12670 JY8QFUQ01AHKU0 productive Homsap IGHV3-48*02 F 971 94.88 204/215 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [0.17.38.11] CARPAGEGDPFFHYYSGLDVW in-frame - ctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12671 JY8QFUQ01DDG20 unproductive Homsap IGHV3-48*04 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDSSRWGYYYYGLDVW# out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcatcttcactagttacagtctgaactgggtccgccaggctccagggaaggGggctggagtgggttgcatacattagtagtagtagtagtaccatagactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaggaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatagtagcaggtggggctactactactatggtttggacgtctgggggtccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggtaacgtggtcatcgcctgcctggtccagggcttcttccc +12672 JY8QFUQ01CTI2D No results +12673 JY8QFUQ01A4ISC productive (see comment) Homsap IGHV1-18*01 F 938 93.87 199/212 nt 93.4 198/212 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt 8 8 8 8.8.8 [X.16.38.11] CARGDYFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 45 in the user submitted sequence), (cause frameshift) ggttacacctttaccagctatggtctcagctgggtgcgacaggccctggccaagggcttgagtggatgggatggatcttcgtttttaacggtaacacaaaatatgcacagcacctccagggcagagtcaccatgaccacagacacatccacggacacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagaggtgactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12674 JY8QFUQ01CHSS6 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-25*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARHEGYNSRYYYFGYW in-frame + gttctggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12675 JY8QFUQ01BVJ75 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12676 JY8QFUQ01CSWDZ No results +12677 JY8QFUQ01DISX1 No results +12678 JY8QFUQ01CM1UV No results +12679 JY8QFUQ01DI7OP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12680 JY8QFUQ01CSA0F productive Homsap IGHV1-18*01 F 862 89.67 191/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [X.17.38.11] CARVPGYGSGPWFFDYW in-frame + ggttacacctttagcagcaatggtatcagttgggtgcgacaggcccctggacaagggcttgagtggctgggcaggatcaacgtatacaatggtaacacggaatatgcagaggacttccagggcagagtcaccatgaccacggacacatccacgaacacagcctatattgaagtgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagtccccggatatggttcgggcccgtggttttttgactactggggccagggaaccctggtcatcgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctccgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttccccca +12681 JY8QFUQ01A1I7O No results +12682 JY8QFUQ01CBQ13 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 7 8 10 7.8.10 [2.17.38.11] CAREVSDALDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 74 of V-REGION: 'GC' (2 nucleotides at position 128 to 129 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 26 in the user submitted sequence), (cause frameshift) gcctctggattcatctttgatgatttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggGCccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12683 JY8QFUQ01DA01D productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1057 99.07 214/216 nt 98.61 213/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [2.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12684 JY8QFUQ01CBXUV unproductive (see comment) Homsap IGHV3-30*15 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARDELPWGYNR#YYFDYW out-of-frame + stop codons ctctggattcacctttagtagatattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttatatcatacgatggaagtagaagaatctacgcagactccgtgaagggccgattcaccatctccagagacacttccaagaacacggtgtatctgcaaatgagtagcctgagacctgaggacacggctgtgtattactgtgcgagagatgagctgccttggggatacaatagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +12685 JY8QFUQ01CYOOE unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.16.38.11] CVSDLAGQKGF#W out-of-frame + in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggcggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggttttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12686 JY8QFUQ01AO80F No results +12687 JY8QFUQ01B7XX9 productive Homsap IGHV3-48*03 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARESWWSGFYGWYDPW in-frame + ctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12688 JY8QFUQ01BLCKL productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.17.38.11] CARGEMTAEYYFDYW in-frame + tctctggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12689 JY8QFUQ01ATKPT productive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggccctatcggtcttccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12690 JY8QFUQ01A7Z02 No results +12691 JY8QFUQ01BFCE0 unproductive (see comment) Homsap IGHV4-61*03 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-1*01 F 3 10 7 X 10.7.X [1.17.38.11] CTRHPEV*CRG#DSW out-of-frame + stop codons tccctggtggctccgtcagcagtggtagttatttctggagctggatccggcagcccccagggcaggggctggaatggatcggttatgtctataacaatgggaacaccaattacaacccttccctcaagagtcgagtcaccatttctatagacacgtccgagaatcacgtctccctgaagctggcctctgtgaccgctgcggacacggccgtgtactactgtacgaggcacccggaagtctaatgtagagggtgactcctggggccagggagccccggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagccctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +12692 JY8QFUQ01A6QNU productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12693 JY8QFUQ01BV2YE productive (see comment) Homsap IGHV1-2*02 F 780 85.78 181/211 nt 84.83 179/211 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-16*02 F 2 8 7 15 8.7.15 [0.16.38.11] CARHYCDTNGVCDFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 73 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 57 of V-REGION: 2 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) tggatacagcttcaccgactttcatattcattgggtgcgacaggaccctggacaagggcttgagtggatgggtggaccacctaaaaatggcggcacgttcattacgctgaagtttcagggcagggtcactatgtccagggacacgtccatgaccacagtctatatggaaatgagcaggctgagatctgacgacacggccatttattactgtgcgagacattattgtgacaccaacggcgtctgtgattttgatatctggggccaggggacaaaggtcatcgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12694 JY8QFUQ01B206Z No results +12695 JY8QFUQ01C0IOK productive Homsap IGHV3-7*01 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + tctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacatggtcgtcgcatgcctggtccagggcttcttccccca +12696 JY8QFUQ01A2WCO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 760 83.8 181/216 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggatcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12697 JY8QFUQ01DJ2FZ No results +12698 JY8QFUQ01CHCZ3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccagccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactc +12699 JY8QFUQ01B2HX0 unproductive (see comment) Homsap IGHV1-58*02 F 930 92.99 199/214 nt Homsap IGHJ2*01 F 193 84.91 45/53 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [0.17.38.11] CAAVLAGWGFY##FDFW out-of-frame + stop codons tggattcacctttaaaagttctgctatacagtgggtgcgacaggcccgtggacaacgccttgagtggataggatggaccgccgttggcagcggtaacacagactacgcacagaagttccaggaaagagtcaccattacgagggacatgtccacaagcacagtctacatggagatgatcaacctgggatccgaggacacggccgtgtattactgtgcggcagtcttggccggctggggattctattgacttcgatttctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12700 JY8QFUQ01AQJ3U productive (see comment) Homsap IGHV4-55*03 P (see comment) 734 82.03 178/217 nt 81.57 177/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 9 7 15 9.7.15 [1.17.38.11] CARDQSVYTAGSYFDSW in-frame + Potentially, because of detected insertion/deletion however the closest V is a pseudogene Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); tctctggtgactccatgagtagcgacacgtggtggagctgggtccgccagacgccagagaagggactggaatggattggggagatcaatcaaagagggacgacctcctacaacccgtccctcaggagtcgagtcgtcctgtcagtgggcgagtccaaaaaGtcaattctccctgaggctgacctctgtgaccgccgcggactcggccatctattattgtgcgagagatcagtctgtctatactgcgggaagttactttgactcctggggccagggaacgctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12701 JY8QFUQ01DD82F No results +12702 JY8QFUQ01AO6RW productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt 86.11 186/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-16*01 F 1 8 7 14 8.7.14 [2.17.38.11] CARCKSAGLVDWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) gcctctggattcagcattagcgactatgccatggcctgggtccgccaggctccagggaaggggccggagtgggtctcaagtgttactaatggttttggcacatactacgcagactctgtgaagggccggttcaccgcctccagagacaattccaagaacgcattgttcttggaaatgaacatcctcagagccgaggacacggccgtatattattgtgcgaggtgtaagtcggccggtttggtggactggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12703 JY8QFUQ01ALD6W productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12704 JY8QFUQ01CQ2DI productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - cctctcgattcacctttagcagctatgtcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +12705 JY8QFUQ01CNGVF productive Homsap IGHV4-61*02 F (see comment) 609 75.45 166/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERDKSVGGANDFDSW in-frame + Low V-REGION identity (75,45% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccagtggccccatgatgagtcgtgacttctattggacttggatccggcagcccgccgggggggaactagaatggatcggacgtgtttacattggtgggatgaccaataacagtccctccttcaggggtcgactgagcatgtccatagacccgaccaggaggcagttctccatgaccttgacgtctgtgaccgccgcagacacggccatgtattactgtgcgcgagaacgtgataagtcggtcggcggagcgaacgactttgattcctggggccagggagtcctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12706 JY8QFUQ01AT8YT productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); tggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtGgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12707 JY8QFUQ01BAGI4 productive Homsap IGHV3-11*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CVTDILRVGVTYYFDYW in-frame + ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggctttcatatattagtggtagtggtgacgacatacattatgcagactctgtgaagggccggttcaccatctccagggacaacgccaagaattcattgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgacagatatccttagagtgggagttacatattactttgactactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12708 JY8QFUQ01BYN47 productive Homsap IGHV1-18*01 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD2-21*02 F 3 8 8 17 8.8.17 [0.17.38.11] CVREESIVVVTGRRGMDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggcctggagtggatgggatgggtcagcggttataatgataaatccaactatgcacagaagttcaaagacagaattatcatgaccacagacatatcaacgagcacagcctacatggagctgaggagcctgagatctgacgacacggccatgtattattgtgttagagaagagtcaattgtggtggtgaccgggcggcggggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12709 JY8QFUQ01CB2DX productive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1105 100.0 222/222 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD6-6*01 F 2 8 10 16 8.10.16 [1.17.38.11] CTRRSIADNFYYYGMDVW in-frame - tctgggttcaccttcagtggctctgctatgcactgggtccgccaggcttccgggaaagggctggagtgggttggccgtattagaagcaaagctaacagttacgcgacagcatatgctgcgtcggtgaaaggcaggttcaccatctccagagatgattcaaagaacacggcgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtactagacggagtatagcagataacttctactactacggtatggacgtctggggccaagggaccacagtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12710 JY8QFUQ01AK1KM productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.16.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaagggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12711 JY8QFUQ01AKUHI productive Homsap IGHV3-7*01 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDPYKPGSGNPGFDYW in-frame - ctctggattcacctttagtgactatttgatgacttgggtccgccaggctccaggaaagggactggagtgggtggccaacataaaagaagatggacttgctacattctatgtggactctgtgagggaccgattcaccatctccagagacaacgccaagaactcactttatttgcaaatgaattacctgagagtcgaggacacggctgtttattattgtgcgagggatccctataaacctggttcgggcaatccgggctttgactactggggccagggagcgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12712 JY8QFUQ01B0MR8 productive (see comment) Homsap IGHV3-72*01 F 970 93.24 207/222 nt 92.79 206/222 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 9 11 8.9.11 [1.17.38.11] CITSFGGRSLAYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12713 JY8QFUQ01BM9UG No results +12714 JY8QFUQ01AI884 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 387 84.26 91/108 nt 8 8 X 8.8.X [1.17.1.X] null - No rearrangement found Low V-REGION identity (84,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagact +12715 JY8QFUQ01B70J3 productive Homsap IGHV1-24*01 F 970 95.31 203/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame + cggaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +12716 JY8QFUQ01CDVE2 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 860 88.53 193/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 2 9 7 15 9.7.15 [1.17.38.11] CLRCHFGTGYYYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'GT' (2 nucleotides at position 51 to 52 in the user submitted sequence), (cause frameshift); gatctggtggctccatcgccagtagtaactggtggagAttgggtccgccaGTgcccccagggaaggggctggagtggattggagagatctatcatactgggaccgtcaactacaacccgtccctcatcagtcgagccaccataggagtggacaagtccaagaatgagctctccttgaggctgacctctgtgaccgtcgcggacacggccgtatattattgtttaagatgtcactttgggactggttattattactactttgactactggggccagggattgctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12717 JY8QFUQ01CWCJ9 No results +12718 JY8QFUQ01DMWYP productive (see comment) Homsap IGHV1-8*01 F 911 92.45 196/212 nt 91.98 195/212 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [X.16.38.11] CAREGLLGSLGSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ggatacaccttcatcagttatgatatcaattgggtgcgacaggccactggacaaggcttgagtggatgggatggatgaaccctaacagcggtaacacagggtttgcacagaggttccagggcagagtaaccatgaccaggaacatctccataaacacggcctacatggagctgaccaacctgacatctgatgacacggccgtatattattgtgcgagagaaggtctattgggcagcctaggatcttggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +12719 JY8QFUQ01CFDIP No results +12720 JY8QFUQ01CGYVT unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD5-24*01 ORF 1 8 7 9 8.7.9 [4.17.38.11] CARGAPFS**C in-frame + stop codons cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12721 JY8QFUQ01BJ8F9 unproductive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1020 95.52 213/223 nt Homsap IGHJ5*01 F 84 62.75 32/51 nt Homsap IGHD4-11*01 ORF 1 8 10 X 8.10.X [1.17.38.11] CARHEGTPVSDVGGYGMDV## out-of-frame + ctctggattcaccttcagtggctctgctatgcactgggtccgccaggcttccgggaaagggctggaatgggttggccgtattagaagcagagcttacagttccgcgacagcatatgcagcgtcggtgaaaggcaggttcaccatttccagagatgattcaaagaacacggtgtatctgcaaatgaacagtttgaaaaccgaggacacggccgtgtattactgtgctagacatgaagggactccagtaagtgatgtaggtggatacggcatggacgtctggggccaaagggtccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatggcctggtccagggcttcttccc +12722 JY8QFUQ01CGNPK productive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12723 JY8QFUQ01A1GVS unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 828 87.1 189/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGFSAWGQDAFDI## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttgggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12724 JY8QFUQ01AMZKQ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12725 JY8QFUQ01COOKR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 937 92.24 202/219 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD4-17*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAKNMGDYMGAPIDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttaccacctacgccatgagctgggtccgccaggctccagggaaggggctggagtggctctcagatatcagtggtagaggttataacacatattacgcagcttccgtgaagggccggttcgccatctccagagacaattccgacaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaaacatgggtgactacatgggcgccccaattgactcctggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12726 JY8QFUQ01BTCFS productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12727 JY8QFUQ01DKQAQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +12728 JY8QFUQ01CCXWM No results +12729 JY8QFUQ01BGT9K productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + cctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca +12730 JY8QFUQ01BW1U7 productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12731 JY8QFUQ01B9S8H productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggactggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12732 JY8QFUQ01CV7GP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +12733 JY8QFUQ01AE42X No results +12734 JY8QFUQ01DNA2K No results +12735 JY8QFUQ01C94TN productive (see comment) Homsap IGHV3-48*01 F 1095 100.0 220/220 nt 99.55 219/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.17.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtagctatagcatgaactgggtccGgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12736 JY8QFUQ01C99TV productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1047 99.07 212/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + ctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12737 JY8QFUQ01C62BK productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 746 83.26 179/215 nt 82.79 178/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tttcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgatggtgtcgtggaactc +12738 JY8QFUQ01BL9OM productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 678 79.91 171/214 nt 79.44 170/214 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 75 of V-REGION: 'GGCT' (4 nucleotides at position 127 to 130 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcgGGCTtgaatcgatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12739 JY8QFUQ01CMLF2 productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 11 8.8.11 [0.17.38.11] CARVIRTNWLDPW in-frame - tggttacacctttactacctatggcatcagctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggaaatacaaactctgcacagaagttccaggacagagtcaccctgaccacagacacatccacgagcacagcctacatggagctgaggaacctgagatctgacgacacggccgtgtattactgtgcgagagtaattcggaccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12740 JY8QFUQ01CLCA0 productive Homsap IGHV1-8*01 F 840 87.85 188/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARVGGTHYHYGVDVW in-frame + cggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagatctgacgacacggccgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12741 JY8QFUQ01CGUKQ productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12742 JY8QFUQ01BQ6NC productive (see comment) Homsap IGHV3-48*03 F 828 87.1 189/217 nt 86.64 188/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ctctgggattcaccttcagttcttatgccatgaactgggtccgcctggtccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12743 JY8QFUQ01CPR1X productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 874 89.04 195/219 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [2.17.38.11] CARLGQLALDYW in-frame - tgttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgattttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12744 JY8QFUQ01A7II3 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 827 85.71 192/224 nt 84.82 190/224 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [2.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); tctctggctggcatgccatcagcagtGataatttcctactggggctggatccgccagcccccagggaagggactgcagtggaCttgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12745 JY8QFUQ01AB534 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 818 86.98 187/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 7 11 8.7.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AB534 ; 8 AA in Homsap_IGHV3-21*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagtttcactggttttaccgtgatctgggtccgccaggctccaaggaaggggctggaatggatctcatccgtcactactaatggtctcacgtactacgcagactcagtagagggccggttcaccatatccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12746 JY8QFUQ01ACT90 productive (see comment) Homsap IGHV4-39*02 F 839 86.88 192/221 nt 85.97 190/221 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctctggtgaccccatcggcaacactgcttactcctgGgggctggatccgccagcCccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +12747 JY8QFUQ01AG2YX productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 904 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 7 8 13 7.8.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) gtctggattcatctcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12748 JY8QFUQ01AG5FJ productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12749 JY8QFUQ01CJYGN productive (see comment) Homsap IGHV3-7*01 F 945 93.09 202/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'GA' (2 nucleotides at position 20 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggattcacatttagtGAattcattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12750 JY8QFUQ01ACRUV productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 881 90.23 194/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12751 JY8QFUQ01AO9EO unproductive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1017 96.77 210/217 nt 95.85 208/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDLYDSSGS#FDYW out-of-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 103 in the user submitted sequence), (cause frameshift) cctctggattcaGccttcagcagctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtaggagtagtaccaaaactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgcgagagatttgtatgatagtagtggttccttttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttctccgaaccggtgacggtgtcgtggaactcag +12752 JY8QFUQ01AGL81 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 672 80.09 169/211 nt 79.62 168/211 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [0.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 76 of V-REGION: 'TTA' (3 nucleotides at position 125 to 127 in the user submitted sequence), (do not cause frameshift); tgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcTTAtcgacagtctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +12753 JY8QFUQ01CS6WP productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame - tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12754 JY8QFUQ01C3JRT productive Homsap IGHV3-48*01 F 1085 100.0 218/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12755 JY8QFUQ01CWUN1 productive Homsap IGHV3-7*01 F 1027 96.8 212/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGFYSTGYW in-frame - gcctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12756 JY8QFUQ01AVHAA productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 810 86.18 187/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-16*02 F 3 8 8 23 8.8.23 [1.17.38.11] CARDRRVFFGQLITTKIYHYGMDVW in-frame - ctctggattcaacttcaattattatagcatgagttgggtccgccaggctccgggaaagggactggagtgggtttcatacattagtactagtagtagttacatgtattacacggactccgtgaagggccgcttcaccgtctccagagacaacgccaagaaatctctgtatctggaaatgaacagcctaagggacgaggacacggctgtctacttttgtgcgagagatcgacgagtgttctttggacaattaataaccaccaaaatctaccactacggcatggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12757 JY8QFUQ01DI2UC No results +12758 JY8QFUQ01BZF4D productive (see comment) Homsap IGHV4-4*07 F 1043 98.6 212/215 nt 97.67 210/215 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD4-11*01 ORF 2 8 7 13 8.7.13 [2.16.38.11] CARDFSNRGWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) gtctctggtggctccatcagtagtttctacCtggagctggatccggcagcccggccggaagggactgagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12759 JY8QFUQ01DLNKW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARGEFYYETSGRRGFDYW in-frame - ctctgggattcaccttcactacctcctggatgcactgggtccgccaagctccagggaaggggctaatgtgggtcgcacgtattaataaggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaccacactgtacttggaaatggacagtctgagagtcgaggacacggctatgtattattgtgcaagaggggaattttactatgaaactagtggtcgaaggggttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12760 JY8QFUQ01BYWUJ No results +12761 JY8QFUQ01AE3VD productive Homsap IGHV3-11*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggcagtgctactaccatatcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaaaaactcactttatctgcaaatggacagcctgagagccgaggacacggccatatattactgtgtgaggcgggtgtggggatacagttatggttccgtttcgtactactttgaatattggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12762 JY8QFUQ01AUYQV productive (see comment) Homsap IGHV3-66*02 F 876 90.19 193/214 nt 89.72 192/214 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD3-16*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAALHDPPWGWLDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); ctctggattcagcgtcaacaacaactacatgaactgggtccgcctggctccagggaagggtctggagtgggtctcagttaAtttatagaggtggtaatacattctacacagactccgtgaagggccggttcaccatctccagagacatttccaagaacactttgtatcttcaaatgaacagtctgacaactgaggacacggctgtgtactattgtgcggccctccacgaccctccttggggttggctcgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12763 JY8QFUQ01CJ1RG No results +12764 JY8QFUQ01AIY7F productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctggattcacctacagcagcGtatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12765 JY8QFUQ01BQDLT productive (see comment) Homsap IGHV1-2*02 F 921 92.52 198/214 nt 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 81 to 86 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacgaccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12766 JY8QFUQ01APUQX unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12767 JY8QFUQ01A1HLF No results +12768 JY8QFUQ01CAVAP No results +12769 JY8QFUQ01B7HDA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12770 JY8QFUQ01CX9PA No results +12771 JY8QFUQ01AFSUH productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +12772 JY8QFUQ01AC5OX productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +12773 JY8QFUQ01BEVTU productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 758 82.81 183/221 nt 82.35 182/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); gtctctgtgactccatcagtagtactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12774 JY8QFUQ01DWST2 No results +12775 JY8QFUQ01ANMI2 No results +12776 JY8QFUQ01DLCNB productive Homsap IGHV3-7*01 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - ctctggattcatgtttagtaactattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagaaagatggtagtgagacttactatgtggaatctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12777 JY8QFUQ01BB7R1 No results +12778 JY8QFUQ01C0MRY productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +12779 JY8QFUQ01BJQ7G unknown (see comment) Homsap IGHV4-4*07 F 890 90.7 195/215 nt 89.3 192/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in CDR1-IMGT at codon 36 of V-REGION: 'TGATTC' (6 nucleotides at position 23 to 28 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagTGATTCtcactactggagttggatccggcagcccgccggGgaagggactggagtggattgggcgtgtctacgccagtgGggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttcggaggttcctacaatttcagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12780 JY8QFUQ01DPWBS productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 973 94.06 206/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [2.17.38.11] CAKGDSGGYTHNYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaAggggctggtgtgggcctcacgtgttaatggtgatAgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattactgtgcaaaaggggatagtggtggttatacccacaactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12781 JY8QFUQ01B641M productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1031 97.25 212/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD1-26*01 F 3 8 8 18 8.8.18 [1.17.38.11] CAKELGRALTGNYYQYFHYW in-frame + cctctggattcacgttcagtggctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtatcatatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctctctctgcaaatgaacagcctgagagctgaggacacggctgtatattactgtgcgaaagaattggggagggccctgactgggaactactaccagtactttcactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12782 JY8QFUQ01C15RE No results +12783 JY8QFUQ01AWG3V No results +12784 JY8QFUQ01DDBA4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12785 JY8QFUQ01BDETF unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12786 JY8QFUQ01A0T6U productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactc +12787 JY8QFUQ01CQHK4 productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 91 to 96 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagttTtctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12788 JY8QFUQ01DWVH3 unknown (see comment) Homsap IGHV1-2*02 F 487 86.72 111/128 nt 8 8 X 8.8.X [0.17.9.X] null + No rearrangement found tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcaggg +12789 JY8QFUQ01CC0UX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12790 JY8QFUQ01CZQ5A No results +12791 JY8QFUQ01BTSHB No results +12792 JY8QFUQ01DPAOU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [2.17.38.11] CARAYSGPGPYYFDYW in-frame - gcctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12793 JY8QFUQ01BBGM9 productive Homsap IGHV4-39*03 F 929 91.36 201/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12794 JY8QFUQ01CH1XL No results +12795 JY8QFUQ01AJ5JP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccag +12796 JY8QFUQ01CQDCU No results +12797 JY8QFUQ01CF50U No results +12798 JY8QFUQ01AURP9 productive Homsap IGHV3-30*10 F (see comment) 702 80.65 175/217 nt Homsap IGHJ1*01 F 152 76.92 40/52 nt Homsap IGHD1-1*01 F 1 8 8 16 8.8.16 [1.17.38.11] CSRGTTGTTDDSRLFQHW in-frame + Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcggcaattacgccatgcactgggtccgccaggctccaggcaagggcctagagtgggtggctgtcataaataaggctgggaagactaaacattatatagactccgtgaagggccgattcaacgtctccagagacaactccgaaaaaacactctatttggagatgaataacgtgggagttgaggacacggctgtatattattgttcgagaggtaccacggggacgacagacgactcgaggttgttccaacactggggccagggcgccctggtcaccgtttcgtcaacatccccgaccagcccccaaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +12799 JY8QFUQ01DBZZM productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1001 95.02 210/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 2 10 7 12 10.7.12 [1.17.38.11] CVRHRRLELLPDYW in-frame + tctctggtgactccatcagcagtaatagtttctactggggctggatccgccagcccccagggaaggggctggagtggattgggaatatctattatagtgggagcacctactacaacccgtccctcgagagccgagtcaccatatccgtagatacatccaggaaccagttctccctgaagctgaggtttgtgaccgccgcagacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12800 JY8QFUQ01BXI5C productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccagGgggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccggctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccgag +12801 JY8QFUQ01B8M0D unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 514 73.0 146/200 nt 72.5 145/200 nt 8 7 X 8.7.X [2.17.31.X] null - No rearrangement found Low V-REGION identity (73,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 85 in the user submitted sequence), (cause frameshift) agcctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtatagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtcatcgcctgcctggtccagggcttcttccccca +12802 JY8QFUQ01B7TWW productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12803 JY8QFUQ01CEETY productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 704 81.6 173/212 nt 81.13 172/212 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.37.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,60% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 129 in the user submitted sequence), (cause frameshift) tctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12804 JY8QFUQ01AFU1L unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F or Homsap IGHV3-74*01 F or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 107 79.41 27/34 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found ctctggattcacctctcctagatactggatgaat +12805 JY8QFUQ01BNYA6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12806 JY8QFUQ01B28V3 productive Homsap IGHV3-11*01 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDDSCSGGSCYEYW in-frame - cctctggattcagtttcagtgactactacatgagttggatccgccaggctccagggagggggctggagtgggtttcatatattgatagcggtggtaccgccatgtactactcagactccgtgaagggccgattcaccatctccagggacaacgccaagaagtcactgtttctgcaaatgagtagcctgagagccgaagacacggccgtgtactattgtgcgagagatgactcttgtagtggtggtagctgttacgaatactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12807 JY8QFUQ01CKN3U productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt 87.61 191/218 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSGSSDYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); cctctggattcagGttttagttcttatgGgcatgaactgggtccgccaggctccatggggggggctggagtgggtctcattcattaacagtgttagtagttacaaatactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaagaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagatagcggctcgtccgactacactaggtacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgaaagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +12808 JY8QFUQ01BKCAT unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12809 JY8QFUQ01AHPL4 productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagg +12810 JY8QFUQ01A5N4V unknown (see comment) Homsap IGHV3-23*02 F, or Homsap IGHV3-23*03 F or Homsap IGHV3-30*05 F 147 53.23 99/186 nt 8 7 X 8.7.X [1.17.28.X] null + No rearrangement found ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12811 JY8QFUQ01C76IX No results +12812 JY8QFUQ01B6LCX unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 750 83.18 178/214 nt 82.24 176/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.37.X] null + Rearranged sequence but no junction found Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 121 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 188 in the user submitted sequence), (cause frameshift) tctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgagggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagcccgaggacacggcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12813 JY8QFUQ01BZCBT No results +12814 JY8QFUQ01B1CH3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.48 192/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 212 to 212 in the user submitted sequence), (cause frameshift); ctctggattcaGcctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttaCtttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12815 JY8QFUQ01C3YLX No results +12816 JY8QFUQ01DTZ4U productive (see comment) Homsap IGHV4-59*03 F 797 85.32 186/218 nt 84.86 185/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVVDYVDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'AC' (2 nucleotides at position 161 to 162 in the user submitted sequence), (cause frameshift); ccgtctctggtgactccattagtggttactattggacgtggatccgacagcgcccagggatgagcctggagtggattggacaagtccattacactgggagcaccaagtacagcccctccctcaagagtcgagtcaccatttctgttgacatgtccaagaaACccaattcaccctcatcttgacctctgtggccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttgttgactacgttgacttttggggtcagggagtcctggtcaacgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12817 JY8QFUQ01B6R1S unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 3 8 7 X 8.7.X [1.17.38.11] CARGDGLR#DYW out-of-frame + ctctggattcaccgtcaatagaaactacataagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacgggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +12818 JY8QFUQ01DVIT1 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 846 87.56 190/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD3-10*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARRNYFGSGSSYNVAGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ttttggatacacctttcccacctactggctcgcctggttccgcctggtgcccgggaaaggcccggagtgggtggggatcatctatcctggtgactccgataccacctatagcccgtccttccaaggccgagtcaccatctcagtcgacctgtccagccgcaccgcctatctgcagtggggcagcctgaaggcctcggacaccgccatctattactgcgcgagacgaaattactttggttcggggagttcttacaatgttgccggcttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12819 JY8QFUQ01CHXLI productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 971 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-3*01 F 2 8 7 22 8.7.22 [1.17.38.11] CARGTRLRDFWSGYPLGGFGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); tctatggtggatccttcagtaattactactggagctggatccgccagTcccccaggggaggggctggagtggattggggaaatcaatcatagtggaagcacgaagtacaatccgtccctcaagaggcgagtcaccatttcagtagacacgtccaagaatcagttctccctgaagctgagttctgtgaccgccgcggacacggctgtgtattactgcgcgagaggcacccgtttaagggatttttggagtggttaccccctgggggggttcggtatggacgtctggggccaagggaccacggtcaccgcctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12820 JY8QFUQ01BPLPH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 3 7 8 15 7.8.15 [1.17.38.11] CAKDQVAGDGYVTYDDW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) cctctggattcactttagcagctatgccatgggctgggtccgccaggctccagggaaggGggctggagtgggtcgcaagtatgagcggtagcggcaagaccatagagcacgcagaccccgtgaagggccggttcaccatctccagagacaactccaagaacacagtgtatctgcaaatgaacagcctgagagccgaagacacggccgtctattactgtgcgaaagaccaggtcgccggagatggttacgtgacctatgacgactggggccagggaaccctggtcaccatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12821 JY8QFUQ01C2G78 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 801 85.71 186/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12822 JY8QFUQ01CEAMW productive (see comment) Homsap IGHV4-39*02 F 983 94.12 208/221 nt 93.21 206/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.17.38.11] CARIVVRQFDQW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); tctctggtgactccatTttccagtactagttattTactggggctgggtccgccagcccccagggaaggggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +12823 JY8QFUQ01CD9B2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1071 99.54 216/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccgggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12824 JY8QFUQ01AFQVN productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaggaattattactggagctggatccggcagTcccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactcag +12825 JY8QFUQ01B6XNK unproductive (see comment) Homsap IGHV3-13*01 F 927 92.17 200/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame - stop codons agcctctggattcacggttcagtaatacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12826 JY8QFUQ01BVH99 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgGttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagcctgagagacgaggacacggctgtgtactactgtgccaaagtgggtaacctgtatttctttgaatactggggccggggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +12827 JY8QFUQ01ACFOO productive Homsap IGHV3-9*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSGGYTHNYFDYW in-frame + ctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagctggaatagtggtagtatagggtatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattactgtgcaaaaggggatagtggtggttatacccacaactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +12828 JY8QFUQ01BQOMW unproductive Homsap IGHV4-61*02 F 911 90.5 200/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-2*01 F 3 10 7 X 10.7.X [1.17.38.11] CASSTSF#LDHW out-of-frame + tctctgatggctccatcggcagtggtactcactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtgtctatgccactgggaaaaccgattacagcccctccctcaagagtcgcgtcaccatatcagtagacacggccaagaaccagttctacctgaccctgaggtctctgaccgccgcagacacggccatttattactgtgcgagtagcaccagtttttttggaccactggggccagggaacgctggtcaacgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttccccca +12829 JY8QFUQ01BO6GI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 940 93.06 201/216 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-2*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARGVGVSWHTEYFQHW in-frame + tctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctccggtattggtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagaggggtcggcgtcagctggcatactgaatacttccagcactggggccagggcaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +12830 JY8QFUQ01CIRW5 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 7 15 8.7.15 [1.17.38.11] CARAKKVRGPPTGMDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagcaaaaaaggttcggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12831 JY8QFUQ01AS3TX productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +12832 JY8QFUQ01BHYWI unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*05 F 948 91.93 205/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 1 8 10 X 8.10.X [1.17.38.11] CVVDIPEVVWG#FDYW out-of-frame + ctctggattctctttcacttatgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttgcccttattaaaagcaaaactagtggtgggacaacacactacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcagagaacacgttctatctacaaatgaatagactgaaaaccgaggacacagccgtgtattattgtgtcgtagatataccagaagttgtgtgggggaatttgactactggggccagggagccctggtttccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgatcatcgcctgcctggtccagggcttcttccccca +12833 JY8QFUQ01CQNEN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 793 84.93 186/219 nt 84.02 184/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [2.17.38.11] CVRVKRFGSGNVLFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 77 of V-REGION: 'A' (1 nucleotides at position 138 to 138 in the user submitted sequence), (cause frameshift); ggctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgAaagggccggttcaAccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +12834 JY8QFUQ01CK280 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 924 91.36 201/220 nt 90.91 200/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 14 10.7.14 [1.17.38.11] CARRALDSSGHYIDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggtggctccatgagcagtggtaattactgctggggctggggccgccagcCccccaggaaaggggctggagtggattggaagtatgtgttatggtgggagcacctactacagcttgtcccccaagggtcgagtcaccatatccatagactcgtcgaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagacgcgcattagacagtagtggtcattacattgacatctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcatcgctgcctggtccagggcttcttccc +12835 JY8QFUQ01A1XYE productive Homsap IGHV4-61*01 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame + tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12836 JY8QFUQ01A7G35 productive (see comment) Homsap IGHV1-8*01 F 822 87.38 187/214 nt 86.92 186/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 12 8.8.12 [0.17.38.11] CARGRGYGSYADHW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tggatacagcttcagcaattatgatatcaactgggtgcggcaggccactggacaagggcttcagtggatggggtggatgaaGcccccacagtgccaatatcgtctacgcgcagaaatttcagggcagagtcaccatgaccagtgacgcctccataaccacagcctacatggaactgagcaacctgaaatctgacgacacggccgtgtattattgtgcgaggggccgagggtacggaagttacgctgaccactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12837 JY8QFUQ01BK953 unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12838 JY8QFUQ01CVT0D unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +12839 JY8QFUQ01AWT6X productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcttccccgaaccggtgacggtgtcgtggcaactca +12840 JY8QFUQ01A9LRE No results +12841 JY8QFUQ01CR6CB productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 903 91.59 196/214 nt 91.12 195/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-1*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARRQLALAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); tggatacaccgttatcacctactggatcgcctgggtgcgccaaatgcccgggaaaggcctggagttgatggggaGtcatctatcctggtgactctgagaccagatacagcccgtccttccaaggccacatcaccctctcagtcgacaagtccatcgataccgcctacctggagtggagcagcctgaaggcctcggacaccgccatgtacttctgtgcaagaagacaactggcccttgcctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12842 JY8QFUQ01DXG9Z productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12843 JY8QFUQ01AQQCI productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12844 JY8QFUQ01CX7EK unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.89 192/216 nt 87.96 190/216 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKNRGVGDG##WYFDFW out-of-frame - stop codons in CDR2-IMGT at codon 58 of V-REGION: 'ATG' (3 nucleotides at position 86 to 88 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'AT' (2 nucleotides at position 209 to 210 in the user submitted sequence), (cause frameshift); tctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattactaATGgtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgATttagtttctgtgcgaaaaataggggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12845 JY8QFUQ01AGDUU productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARPGVGASSFIDFW in-frame + ttctggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12846 JY8QFUQ01CGIGB unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 792 84.79 184/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12847 JY8QFUQ01CK70G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12848 JY8QFUQ01B02KX productive (see comment) Homsap IGHV3-48*01 F 1080 100.0 217/217 nt 99.54 216/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12849 JY8QFUQ01A3JDG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'C' (1 nucleotides at position 142 to 142 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggcCtggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctCccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12850 JY8QFUQ01DWPG0 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12851 JY8QFUQ01B1P1S unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12852 JY8QFUQ01C1PBT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 828 87.1 189/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGFSAWGQDAFDIW in-frame + ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12853 JY8QFUQ01BMS0L No results +12854 JY8QFUQ01AUPO3 productive (see comment) Homsap IGHV3-7*01 F 944 93.49 201/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 7 10 8.7.10 [1.16.38.11] CGTGSGWEVEYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctggattcgccgttaatagtcattggatgaattgggtccgccaggctccagggaaggggctggaatggtggccaacatacaacaagatggagtgagaaaaactatgtggactctgtgaagggccgattcaccatctcccgagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctctctattactgtgggactggcagtggctgggaagttgaatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12855 JY8QFUQ01BSXDM No results +12856 JY8QFUQ01CVV67 No results +12857 JY8QFUQ01C0UKA No results +12858 JY8QFUQ01DS988 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 932 92.2 201/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + cctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12859 JY8QFUQ01AIQ7B No results +12860 JY8QFUQ01AHOJP productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12861 JY8QFUQ01ATAPM No results +12862 JY8QFUQ01BTSOV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ2*01 F (see comment) 94 64.15 34/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggcccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12863 JY8QFUQ01A8QLW No results +12864 JY8QFUQ01A0QIG productive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [0.17.38.11] CARYGDYELGGDFW in-frame + tggaggcgccttcagcacctatagaatcatttgggtgcgacaggcccctggacaagggcttgagttgatgggagggatcgtccctatctttggcgcaccgaactacgcacagaagttccaggacagaatcaccattaccgcggacgaatccacgagcacggcctacatggagttgagtagcctgagatctgaggacacggccgtgtatttctgtgcgagatacggtgactacgaactcggcggtgacttctggggccagggaaccctggtcaccgtctcctcggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12865 JY8QFUQ01BMULR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame + cctctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgacgcctctgcagcacccagccagatgggaacgtgtcatcgctgcctggtccagggcttcttccc +12866 JY8QFUQ01DPITD No results +12867 JY8QFUQ01DSH2U unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 125 56.52 65/115 nt 8 10 X 8.10.X [1.17.2.X] null + No rearrangement found ctctggattcagctttagttactattggatgagctgggtccgccaggctcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12868 JY8QFUQ01AJP1M unknown (see comment) Homsap IGHV4-30-4*01 F, or Homsap IGHV4-30-4*02 F or Homsap IGHV4-30-4*03 F (see comment) 398 65.4 138/211 nt 10 7 X 10.7.X [1.17.35.X] null + No rearrangement found Low V-REGION identity (65,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcgggtgcttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgccctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +12869 JY8QFUQ01DFEAQ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 483 89.17 107/120 nt 88.33 106/120 nt 8 7 X 8.7.X [1.17.6.X] null - No rearrangement found in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) ctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgca +12870 JY8QFUQ01B0236 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +12871 JY8QFUQ01DQCT2 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1043 98.6 212/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-19*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARDIGSGWIDALHIW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattggccatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagatgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagagatattggcagtggctggattgatgctttacatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12872 JY8QFUQ01A6CNG productive Homsap IGHV4-61*01 F (see comment) 767 83.26 184/221 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12873 JY8QFUQ01BZ35D productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 643 77.78 168/216 nt 77.31 167/216 nt Homsap IGHJ3*02 F (see comment) 142 76.0 38/50 nt Homsap IGHD1-1*01 F 3 8 8 17 8.8.17 [1.17.38.11] CAKDIWAREWNDMAAFQMW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (77,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); ccccggaatcattttcccagctatgtcatgagttgggtccgccaggccccagggaaggggctggaggtggtgcaggcaagcattagtGcagggcgacagttcatactacgcagactccgtgaagggccgattcaccatctccagggacaatcccaggaccacattgtatctggaaatgaacagtctgagagtcgaagacacggccacatattattgtgcgaaagatatctgggcgcgagagtggaacgacatggcggcttttcagatgtggggccaggggacacttgtcattgtctcgtcagctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12874 JY8QFUQ01CLL4N productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 903 89.69 200/223 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 2 8 10 12 8.10.12 [1.17.38.11] CTITVRPDDYHDYW in-frame + ctctggagtcactttcactaacgtgtggatgagttgggtccggcaggctccagggaaggggccggagtgggttggccgtattaaaagggagactgagggggggacaatagactacgctgcacccgtgacagcaagattcaccatgtcaaaagatgattcaaaaaacacactatatctgcaaatgaacaacctgaaaatggaggacacagccgtgtattactgtaccataacagtccgaccggatgattaccatgactactggggccagggaaccctggtgaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggctccagg +12875 JY8QFUQ01AZWXX unproductive (see comment) Homsap IGHV3-9*02 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.17.38.11] CVKDKDKVGGPHWPLSH#FDFW out-of-frame + stop codons Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaaccccgaaaactttgccatgcactgggtccgacaagttccagggaagggcctgaagtgggtctcaggtataaattggaatggacgaaaaacaggatatgcggagtctgtgaggggccggttcaccatctccagagacaatgacaagaacgtcctttctttgcaaatgaccaatttggggactgaggacacggccttctatttttgtgtgaaagataaggacaaagtggggggtccacactggccattatcccacgtttgacttctggggccagggagccctggttaccgtcgcatcagcctccaccaaggactacttccccgaaccggctgacggtgtcgtggaactca +12876 JY8QFUQ01BU4RC unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 948 91.93 205/223 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 8 10 X 8.10.X [1.17.38.11] CTTDRRGSDIPPQ#FDYW out-of-frame + stop codons ctctggatttagtttcaataacgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaagctgatggtggggcggcagactacggtgcacccgtgagaggcagattcaccatctcaagagatgattcaagaggcacggtgtctctgcaaatgagcagcctgaaaaccgaggacacagccatctattattgtaccacagataggaggggttcggatattccacctcaattttgactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +12877 JY8QFUQ01BNHKI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12878 JY8QFUQ01CCVIK unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 454 71.28 134/188 nt 6 8 X 6.8.X [X.17.31.X] null + No rearrangement found Low V-REGION identity (71,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release agcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtcatcgcctgcctggtccagggcttcttccccca +12879 JY8QFUQ01CUBKO productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +12880 JY8QFUQ01DB4T3 No results +12881 JY8QFUQ01B34YK unproductive Homsap IGHV3-64*02 F, or Homsap IGHV3-64*04 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CANEVGYCSGG# out-of-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtgggggggccagggaaccctggtcaccgtctcctgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12882 JY8QFUQ01DD6CC unproductive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD2-15*01 F 3 10 7 X 10.7.X [1.17.38.11] CATIVPSSVTALINDQGRFYFDH## out-of-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggccctatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtcgtcgtggaactcag +12883 JY8QFUQ01BOQGM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12884 JY8QFUQ01AEZ8T unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [2.17.38.11] CAREVKYGDDTGGWFD#PG out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); agcgtctggattcaccttcagtgactctggcatgcactgggtccgccaggctccaggcaaggGggctggagtgggtggcacttatatggtatgatggatattataaacaacatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattactgtgcgagagaggtgaaatacggtgacgacacgggggggtggttcgacccctgggggccagggaaccctggtcaccgtctcatcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12885 JY8QFUQ01CCRGO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12886 JY8QFUQ01DCA4Q unproductive (see comment) Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKRLAEQRLVPF*G#W out-of-frame - stop codons cctctggattcacctttgatgagcatgccatgcactgggtccggcaagttccggggaagggcctggagtgggtctctggtgttacttggaatagtggtgtcatagactatgcggactctgtgaagggccgattcaccatctccagagacaacgccaggaattccctgtatctacaaatgaacagtctgagaactgatgacacggccttctatttctgtgcaaaaagattggccgagcagcggctggtcccattttgaggcttggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctttcccca +12887 JY8QFUQ01BTGBR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12888 JY8QFUQ01A1WLI productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 897 90.0 198/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12889 JY8QFUQ01CY3ZT productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.16.38.11] CSKDTFGREDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 2 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) cctctggattctccgtcagtaattactggatgcactgggtccgccaggctccagggagggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12890 JY8QFUQ01B8J1O unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F (see comment) 623 80.31 155/193 nt 8 7 X 8.7.X [1.17.31.X] null + No rearrangement found Low V-REGION identity (80,31% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaaggactacttccccgaaccggtgacggtgtcgtggaactca +12891 JY8QFUQ01CAYIT productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-9*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARGGVDILTGFYDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ttctggatacagctttggcaccgcctggctcggctgggtgcgccagacgcccgggaAaaggcctggagtggatggggaccatccatcctgctgactctgatacaaaatacagcccgtccttccagggccaagtcaccatctcggtcgacaggtccatcaacaccgcctacctgcagtggagcagcctggaggcctcggacaccgccatgtatttctgtgcgcggggaggagtcgatattttgactggtttctatgatgctttcgatatctggggccaagggaccatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +12892 JY8QFUQ01DCFT6 productive Homsap IGHV3-9*01 F 892 89.95 197/219 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [2.17.38.11] CARTYGDHDGMDVW in-frame - gtctctggattcacctttgatgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtattagttggaacagtggtaagatagactatgcggacgctgtgaagggccgattcatcacatccagagacaatgccaagaactccatctatttgcaaatgaacagtctgagagatgacgacacggccttctacttctgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +12893 JY8QFUQ01BPWQZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); cctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtgGgtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +12894 JY8QFUQ01DUY13 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 97 52.67 69/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +12895 JY8QFUQ01CYMW5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 974 93.67 207/221 nt 93.21 206/221 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARPFSGRWCFDLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'AT' (2 nucleotides at position 85 to 86 in the user submitted sequence), (cause frameshift); cagcctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacgaaATtcaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12896 JY8QFUQ01CU8KI unproductive (see comment) Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + stop codons ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgtaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12897 JY8QFUQ01DRKCQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 977 94.5 206/218 nt 93.58 204/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [2.16.38.11] CATAPLGSSNWDAFEMW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'GGTCGTCAT' (9 nucleotides at position 84 to 92 in the user submitted sequence), (do not cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) gcctctggattcacccttaggaattatgccatgagctgggtccgccaggctccagggaaggggctgagtgggtctccgctattGGTCGTCATggtggtagtggcggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacatttccgagaacacgctgtatgtgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgacagctcccctggggagcagcaactgggacgcttttgagatgtggggccaagggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12898 JY8QFUQ01BEGXL productive Homsap IGHV3-11*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFDYW in-frame - ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcatacattagtgggagtgcgactaccatatcctacgcagactttgcgaagggccgattcaccatctccagggacaacgccaagaactcggtgtatctgcaaatgaacagcctgagagccgaggacacggccacgtattattgtgtgaggcgggtctggggatatagttatggttccgtttcgtattacttcgactactggggccagggaatcccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12899 JY8QFUQ01A1963 productive (see comment) Homsap IGHV3-64*02 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 7 8 10 7.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) tctggattcatttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +12900 JY8QFUQ01AUQ13 No results +12901 JY8QFUQ01B2NTW productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 869 90.91 190/209 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 7 7 11 7.7.11 [X.17.38.11] CAISSGFYSTGYW in-frame - ggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12902 JY8QFUQ01DK7D4 No results +12903 JY8QFUQ01BJIWU No results +12904 JY8QFUQ01BMDY0 unknown (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*03 F or Homsap IGHV4-59*07 F (see comment) 458 67.91 146/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (67,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12905 JY8QFUQ01B956I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12906 JY8QFUQ01CNCW4 productive (see comment) Homsap IGHV1-24*01 F 970 95.31 203/213 nt 94.84 202/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); cggaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgCatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagcccaaggtcttcccgctgagcctctgcaagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +12907 JY8QFUQ01BBZDL productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 868 89.35 193/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + tcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12908 JY8QFUQ01CGPP0 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 165 75.0 45/60 nt 8 X X 8.X.X [1.10.X.X] null - No rearrangement found gctctggattcaacttcagaacctattggatgggctgggtccgccaggcttcttccccca +12909 JY8QFUQ01A1BT3 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-16*02 F 2 8 7 19 8.7.19 [1.17.38.11] CARSSDYLWGSYRYPYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagttacttctggagttggatGccggcagcccccagggaagggactggagtggattggatatgtctattacagtggaagtaccaagtataatccttccctcgaaagtcgagtcaccatatcattagacacgcccaacaaccagttctccctgagcctgacctatgtcaccgctgcggacacggccatatactactgtgcgagaagctctgattacctttgggggagttatcgttatccctactacttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12910 JY8QFUQ01BMCAM productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12911 JY8QFUQ01BZ7IE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 8 8 10 8.8.10 [1.17.38.11] CATWIQSHFDYW in-frame + ctctggattcacatttagtcactataccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagccattaatcaagatgccattaccacacactacccagactccgtgaagggccgcttcaccgtctccagagacaattccaagaacacactctatctgcaaatgagcagcctgagagccgacgacacggccgtatattattgtgcgacgtggatacagtctcactttgactattggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggct +12912 JY8QFUQ01DWONA productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 782 83.48 187/224 nt 83.04 186/224 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 13 8.10.13 [1.17.38.11] CATDSPTGYYAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); cctctgggttcGattttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12913 JY8QFUQ01C3SV7 unproductive Homsap IGHV4-61*02 F 863 89.3 192/215 nt 88.37 190/215 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 8 7 X 8.7.X [1.17.38.11] CARQGDSSGPWNDY## out-of-frame + in CDR1-IMGT at codon 36 of V-REGION: 'CTGGTT' (6 nucleotides at position 22 to 27 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift); tctccggtggctccatcagtaCTGGTTattactactggagctggatccggcagtccgccgggaagggattggaatggattgggcgcatgtctgccagaggggacagcaactacaaccccGtccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttttccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtg +12914 JY8QFUQ01CMFGL No results +12915 JY8QFUQ01DUT18 No results +12916 JY8QFUQ01ALZGA productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 742 82.87 179/216 nt 81.94 177/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 2 7 8 15 7.8.15 [1.17.38.11] CARYRVGDSLYYGLDGW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 58 of V-REGION: 'CAC' (3 nucleotides at position 87 to 89 in the user submitted sequence), (do not cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctctggattcattttagaaattttgccatgagttggctccgccaggcaccagggaaggggctggaatgggtctcgactatcagcagCACtagtggtgacacggcatattactcagactccgtgaggggccgcttttccatctccagagacaactccaagagcactctgttcttgcagatgaacagcctgagtgccgaagacacggccatttactactgtgcgagataccgtgtgggtgacagtctctactacggtttggacggctggggccaagggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12917 JY8QFUQ01B4FQA unproductive Homsap IGHV3-48*02 F 971 94.88 204/215 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [0.17.38.11] CARPAGEGDPFF##YYSGLDVW out-of-frame - ctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12918 JY8QFUQ01BY80F productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12919 JY8QFUQ01A30CD productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccagccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12920 JY8QFUQ01B77RX No results +12921 JY8QFUQ01BUGW0 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); gtctggattcacgtttagtagAttttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12922 JY8QFUQ01ANAE8 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 198 93.33 42/45 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found ctctggattcaccttcagcaagtatgccatgagctgggtccgcca +12923 JY8QFUQ01BO7N4 productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +12924 JY8QFUQ01CCLO8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - tctggagttcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12925 JY8QFUQ01CFIZH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F (see comment) 103 62.9 39/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggcccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +12926 JY8QFUQ01A7TII No results +12927 JY8QFUQ01A4MST unproductive Homsap IGHV3-11*01 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ5*01 F 102 66.67 34/51 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRDYYYYGMDV## out-of-frame + in CDR2-IMGT at codon 63 of V-REGION: 'GGG' (3 nucleotides at position 96 to 98 in the user submitted sequence), (do not cause frameshift); cttctgggttctccttcagcgactacttcatgagttgggtccgccaggctccagggaagggactggagtgggttgcatacattagtagtagtggtGGGactactaaatactacgcagactctgtgaagggccgattcaccatctccagggacaacggcaagaattcattgtttctgcaaatggacagcctgagagtcgacgacacggccatgtatttctgtgtgagagactactattattacgggatggacgtctggggcccaagggaccacggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca +12928 JY8QFUQ01CEVA5 productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-2*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDRTLHTPAQMFYYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift); catctggattcaccttcagttcttatagtgtaaAactgggtccgccaggctccagggaagggcctagagtttgtctcatacattgatagtagtggttctaccatatactacgcagactctgtgaagggccgattcaccatctctagagacaatgcccagaactcactgtttctgcaaatgaacaacctgcgagtcgacgacacggccgtatattactgtgcaaaagaccggacacttcacacacccgctcagatgttttactatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatctccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +12929 JY8QFUQ01BGO68 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12930 JY8QFUQ01CKQHV productive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 10 7 22 10.7.22 [1.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtcgtcgtggaactcagg +12931 JY8QFUQ01C9R55 productive Homsap IGHV3-48*04 F 963 94.01 204/217 nt Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARRGTQLGYCASPSCPTDLW in-frame + ctctggattcaccttcagtagttataccatgcactgggtccgccaggctccagggaaggggctggagtgggtttcatatattagtagtactagtagtaccataaactacgcagactctgtgaagggccgattctccatctccagagacaacgccaggaactcagtggatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcgaggaggggaacacaactgggatactgtgctagccctagctgcccaactgacttgtggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttc +12932 JY8QFUQ01B7MFV productive Homsap IGHV3-48*02 F 864 88.94 193/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD6-6*01 F 1 8 8 20 8.8.20 [1.17.38.11] CARDDSRLWSSSFNHYFAMDVW in-frame + ctctggattcacctttagtgattatagaatgaattgggtccgccaggctccagggatggggctggaatgggttgcacacattagtaccagtggtagtagtatatactatgcagactctgtgaagggccgattcaccgtctccagagacgatgccaagaattcactttttctgcaaatggacagcctgagagacgacgacacggctgtatattactgtgcgagagacgattcacggctgtggagctcgtcatttaaccactatttcgctatggacgtctggggccaagggaccaccgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12933 JY8QFUQ01A2LM7 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 910 90.87 199/219 nt 90.41 198/219 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [2.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); gggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatCggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12934 JY8QFUQ01APK90 unproductive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [1.17.38.11] CARGSYWHYDTFGDY## out-of-frame + cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattgggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +12935 JY8QFUQ01BF8LB No results +12936 JY8QFUQ01BQ2G8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 928 91.78 201/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [2.17.38.11] CASDLGGQKSYW in-frame - gcctcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12937 JY8QFUQ01DFSO3 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARKRVPGGVLFMGDY## out-of-frame + in FR2-IMGT at codon 50 of V-REGION: 'GC' (2 nucleotides at position 62 to 63 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggGCctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccgggggggtactttttatgggggactactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctggggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12938 JY8QFUQ01ASUCZ productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 824 86.7 189/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-17*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARHSGALATGSQNWFDPW in-frame - cgtcgggatttaggtttgatgattttggcatgagctgggtccgccaagttccagggaagggcctggaatgggtctctggtagtgactggagtggtggaagaacaggttatggtgactctgtgaagggacgattcatcatctccagagacaacgccaagaactccctatatctacaaatgaacgatctgcgagccgatgacacggccgtctattattgtgcgcgacatagtggggcgctggctactgggtctcagaactggttcgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12939 JY8QFUQ01A7CQO No results +12940 JY8QFUQ01CEGC4 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggacCtccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12941 JY8QFUQ01A15L6 productive (see comment) Homsap IGHV4-61*02 F 816 85.91 189/220 nt 85.0 187/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 10 7 18 10.7.18 [1.17.37.11] CAREDYYGSGSYGRAWFDSW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) tctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtCgggggtgtcgactacaaccctccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagaggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12942 JY8QFUQ01DR1MK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +12943 JY8QFUQ01BV9QC unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +12944 JY8QFUQ01AFKQK productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12945 JY8QFUQ01DM4PH No results +12946 JY8QFUQ01BB9QJ productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 680 78.9 172/218 nt 77.98 170/218 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIVREGLDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (78,90% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'AC' (2 nucleotides at position 51 to 52 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); tgtctggtggctccatcgccacttatcattggtggaattgggtccgccagACcccccggggaaggggActggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccggaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +12947 JY8QFUQ01AJEGM No results +12948 JY8QFUQ01CFD3R No results +12949 JY8QFUQ01BGY6V productive Homsap IGHV4-31*06 F 974 93.64 206/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARDRGPSSSSKMEYDYW in-frame - tctctggtgcctccgtcagcagtggtagtttctactggacctggattcgtcagcacccagggaagggcctggagtggattgggtacatctattacagtgggagcgcctactacaacccgtccctcaagagtcgagttgccatatcaatagacacgtctaagaaccagttctccctgaacttgagttctgtgactgtcgcggacacggccgtttattactgtgcgagagatcggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12950 JY8QFUQ01CIQ3H productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1057 99.07 214/216 nt 98.61 213/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [2.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12951 JY8QFUQ01AJV3S productive Homsap IGHV4-61*02 F 875 88.69 196/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + tctctggtggccccatcagcagcagcacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +12952 JY8QFUQ01AVA4S No results +12953 JY8QFUQ01AZFDY No results +12954 JY8QFUQ01BF83C No results +12955 JY8QFUQ01BBG80 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CAKRPPGTIDRW in-frame + cctctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccgattcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12956 JY8QFUQ01CAI7Q productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 889 88.74 197/222 nt 87.84 195/222 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-19*01 F 2 10 7 16 10.7.16 [2.17.38.11] CTNDHSMAVSAKHAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); gtctctggtgcctccGatgagcaCgtagtgcatactactggggctgggtccgccagacccccgggaaggggccggagtggattgggagtgtctactatggtgggagcacctactacaacccgtccctcaagagtcgggcctccatttctgtcgacacgtccaggaacgagttctccctgaggctgaactctgtgaccgccacagacacggctatgtattactgcacgaacgaccattcaatggcagtctctgctaagcatgcttttgatgtttggggtccagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12957 JY8QFUQ01BGMLL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 447 93.14 95/102 nt 8 7 X 8.7.X [1.17.X.X] null + No rearrangement found ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacac +12958 JY8QFUQ01BNGZQ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12959 JY8QFUQ01AVMMR productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame + tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +12960 JY8QFUQ01AY632 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12961 JY8QFUQ01C8750 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +12962 JY8QFUQ01BA5ST productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-14*01 ORF 3 8 8 19 8.8.19 [1.16.38.11] CARIIPYDPRTDYYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) cctctggattcagcttcagtaattatatcatgacttggtccgccaggcccagggaaggggctggagtgggtctcatctattagtggaagtagtagtaacatattctacgcagactcaatgaagggtcgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaataatcccgtatgacccgaggaccgactattattactatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +12963 JY8QFUQ01A32N8 No results +12964 JY8QFUQ01B2AZY No results +12965 JY8QFUQ01AE9M1 productive (see comment) Homsap IGHV3-30*01 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggGggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12966 JY8QFUQ01CH7KP productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1016 95.09 213/224 nt 94.64 212/224 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-2*01 F 1 8 10 13 8.10.13 [1.17.38.11] CTSSQDQLITSFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctgggttcaccttcagtgtctctcctatgcactgggtccgccaggcttccgggaAaagggctggagtgggttggccgtattagagacaaagctaacacttacgcgacaacatatgctgcgtcggtgaaaggcaggttcaccatcgccagagatgattcaaagaacacgacatatctgcaaatgaacagcctgaaaatcgaggacgcggccgtgtattactgtactagttctcaggaccagttgataacgtcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12967 JY8QFUQ01CQPJ6 unproductive (see comment) Homsap IGHV3-7*01 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggatttaGgctttagaaccttttggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12968 JY8QFUQ01APV5G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 834 86.82 191/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [2.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame - agcctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggttcagggcttcttccccca +12969 JY8QFUQ01BS42T No results +12970 JY8QFUQ01CINRZ productive Homsap IGHV3-48*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12971 JY8QFUQ01BU3DY productive Homsap IGHV3-11*01 F 981 94.93 206/217 nt Homsap IGHJ6*01 F 252 88.89 56/63 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [1.17.38.11] CVRYWGSYYYYNGLDVW in-frame + ctctggattcaccttcactgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcacacattagtagtggtggtagaaccattgcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtttctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgagatattggggcagctactattactataacggtctggacgtctgggggcaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca +12972 JY8QFUQ01B2GL4 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagactgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +12973 JY8QFUQ01DN9QX No results +12974 JY8QFUQ01CWDBY unknown (see comment) Homsap IGHV4-61*02 F 884 89.14 197/221 nt 88.69 196/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggGAaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttcggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggccctatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc +12975 JY8QFUQ01C1RZA unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaagccctggctnaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgntgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +12976 JY8QFUQ01C7LPO productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame + tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgacgggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +12977 JY8QFUQ01C80HI productive Homsap IGHV4-4*07 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [2.17.38.11] CARQRGGGDRQWAFENW in-frame - tgtctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12978 JY8QFUQ01BCD9X productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12979 JY8QFUQ01BYE5A productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12980 JY8QFUQ01CP7A0 No results +12981 JY8QFUQ01DGG26 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12982 JY8QFUQ01DC9TA productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12983 JY8QFUQ01DXHGU productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 841 87.96 190/216 nt 87.04 188/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 7 8 17 7.8.17 [1.16.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) cctctggattcagtttagtacacatggcatgaactgggtccgccaggctccagggaagggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12984 JY8QFUQ01B030E unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 165 75.0 45/60 nt 8 X X 8.X.X [1.10.X.X] null + No rearrangement found gctctggattcaacttcagaacctattggatgggctgggtccgccaggcttcttccccca +12985 JY8QFUQ01CPNBB unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-7*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDCDSGECNFDY## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ1*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccaagggaaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12986 JY8QFUQ01CB9YO No results +12987 JY8QFUQ01B30T6 unknown (see comment) Homsap IGHV3-48*01 F 1041 97.27 214/220 nt 96.82 213/220 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); gcctctgggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacaGttagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccgcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12988 JY8QFUQ01C8IHX productive Homsap IGHV3-13*01 F 976 94.91 205/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame - gcctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12989 JY8QFUQ01A8XJC unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1017 96.77 210/217 nt 96.31 209/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.16.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 49 of V-REGION: 2 nucleotides (from position 63 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctgagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactgggggccagggaagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12990 JY8QFUQ01BTEZT productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12991 JY8QFUQ01APCHX productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt 95.85 208/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12992 JY8QFUQ01BWALA productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacaGacccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12993 JY8QFUQ01AUUNC unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYFGTL#DYW out-of-frame + stop codons gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttggaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +12994 JY8QFUQ01CZZGJ productive (see comment) Homsap IGHV3-7*01 F 1008 96.31 209/217 nt 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12995 JY8QFUQ01B9OTU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +12996 JY8QFUQ01AQ20J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +12997 JY8QFUQ01DS3UV productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 920 90.95 201/221 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 1 10 7 12 10.7.12 [1.17.38.11] CAWGWFGLNYFDYW in-frame + tctctggtggctccgtcagaagtaccagttactactggggctggatccgccagcccccagggaaggggctggagtggattagtaacattcattctagtggaaccacctactacaacccgtccctcaacagtcgagtcaccatgtccgtaaacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcggacacggctgtatattactgtgcatgggggtggttcggactgaactactttgactactggggcccgggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +12998 JY8QFUQ01ADUCB unproductive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAGAEAGLLTY## out-of-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcgggggcagaggctggcttattgacgtactggggccctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +12999 JY8QFUQ01CB61D productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13000 JY8QFUQ01B1GMB No results +13001 JY8QFUQ01BXO6Y productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13002 JY8QFUQ01DLL4K unknown (see comment) Homsap IGHV3-74*03 F 116 54.14 72/133 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13003 JY8QFUQ01BGM4F productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 894 91.12 195/214 nt 90.65 194/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-18*01 F 1 8 8 15 8.8.15 [0.17.38.11] CAIVDTNLVSATGKDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcagcaactactatagacactgggtgcgacaggCcccctggacaagggcttgagtggatgggaatgatcaaccctagtagtgattacaaatattacgcacagaaatttcagggcagagtcaccatgaccagggacacgtccacgagcacagtcttcatggagctgagtagcctgagatctgacgacacggccgtgtattattgtgcaatagtggacacaaatttggtttcggcgaccggtaaagactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13004 JY8QFUQ01BCC02 productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 854 87.05 195/224 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD4-23*01 ORF 3 8 10 14 8.10.14 [1.17.38.11] CSRRSTLVTGYVFDKW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) cctctggaatcaactttcgtgatcatgccatgagctggttccgccaggttccagggaaggggctggagtgggtaggtttcattagaagttctcaatacggtggagatacagaatacgccgcgtctgtggaaggcagattcaccatctcaagagacgattccaaaagcatcgcctatttggatatgaatagcctgaaaatcgacgacacagccctatattactgttcccggaggtcgacgttggtgactggatacgtctttgacaagtggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13005 JY8QFUQ01AND5U productive (see comment) Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 744 82.19 180/219 nt 81.74 179/219 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD2-15*01 F 3 10 6 15 10.6.15 [1.17.38.11] CARVWVAGSRDENFDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) tctcgggtggttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtggggcacctattacaacccgtctctcaagagtcgacttgacctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13006 JY8QFUQ01CLIT1 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.38.11] CARGRTVVTVIDYIDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); tctctgggggActccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13007 JY8QFUQ01CCVOC unproductive Homsap IGHV1-2*02 F 777 85.05 182/214 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [0.17.38.11] CARVRGIVANKTLPR#ALDVW out-of-frame - tggatacaccttcaccggctactatttgcactgggtacgacaggcccatggacacggggttgagtctctggggtggctccaccctgaaagcggcagcacgaattatgcagagaagtttgggggcagggtcaccatgacccgggacacgtccatcagcactgcctacatggagctgaaaagtctaacactggacgacacggccgtctattactgtgcgagagttcggggcatagtggcgaacaaaaccctcccgcggggctttggatgtctggggccaggggacaatggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13008 JY8QFUQ01APR9P productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARADNYDSLGLKFDPW in-frame + tctctggtgactccatcagtagtaactactggaactggatccggcagcccccagggaagggactggagtggattgggtatatctatcacagtgggagcaccagctacaacccctccctcaggagtcgagtcaccatatcattagacacgtccaagaaccagttctccctgaaactgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggcggataattatgatagtcttgggctgaagttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +13009 JY8QFUQ01A0LAJ productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 845 86.61 194/224 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-22*01 F 2 8 10 11 8.10.11 [1.17.38.11] CTWDSTGYFRLTW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggactcactttcagtgacgcctggatgacctgggtccgccaggttccagggaaggggctggagtgggttgcccatattagatggaactctgatgactggaccacagactacgctactcccgtgaagggcagattcaccatctcaaaagatatttcagagaacacgctgtatctacaaatgaacagcctgataagcgaggatacaggcgtttattactgtacctgggacagcactggttattttcggcttacctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13010 JY8QFUQ01AXVTD unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 130 52.51 94/179 nt 8 8 X 8.8.X [1.17.25.X] null - No rearrangement found tctggattcaccttcagtagctatggcatacactgggtccggcaggctccagggagggggctggagtgggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13011 JY8QFUQ01ADGJZ productive (see comment) Homsap IGHV3-11*01 F 797 85.32 186/218 nt 84.86 185/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CVREVTGVWDWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); ctctgggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggGggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13012 JY8QFUQ01B9HCQ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 873 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [1.17.38.11] CARVRDGSKQPPDWW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcatgttcagtgcctatggcatgaactgggtccgccaggctccagggaaggggctggaatgggtctcatccattagtagcggtggcacttacatatcatacgcaaactcagttaagGgggcgattcaccgtntccagagacaacaccaagaattctctgtttctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgcgagagtcagagatgggtccaagcaacccccggactggtggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13013 JY8QFUQ01CCL9J productive (see comment) Homsap IGHV3-11*01 F (see comment) 770 83.94 183/218 nt 83.49 182/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARVRCSGNTCGAFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); cctctggattcagcttaagtgactactacatgacctgggtccgccaggccccagggaagggactggagtggctcgcctacattagtcgaactgatgattccgtatattccgcagagtctgtggtgggccgattcaccgtctccagggacaacgtccaaaactcactgTtttttgcagatgattggcctgagagacgaggacacggccgtatattactgtgcgagagtccgctgtagtggtaatacctgcggggcttttgatttgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13014 JY8QFUQ01CCXME productive Homsap IGHV3-9*01 F 868 89.35 193/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDRKGSNWYYFENW in-frame - tctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13015 JY8QFUQ01BHE4O No results +13016 JY8QFUQ01C2MRC productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13017 JY8QFUQ01C0SYV productive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13018 JY8QFUQ01CPDTA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 998 96.28 207/215 nt 95.35 205/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.16.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaagggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13019 JY8QFUQ01COJ8F productive (see comment) Homsap IGHV3-66*02 F 885 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcagtagcagcttcatgActtggggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaaggGgccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13020 JY8QFUQ01A0HSP No results +13021 JY8QFUQ01BHDAI No results +13022 JY8QFUQ01DF8VY unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 625 93.01 133/143 nt 8 8 X 8.8.X [1.17.13.X] null - No rearrangement found gctctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctcc +13023 JY8QFUQ01C2B9H unknown (see comment) Homsap IGHV3-7*02 F 118 60.24 50/83 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found cctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13024 JY8QFUQ01ALWGF unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 728 82.33 177/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDWGGSFDRY#FDYW out-of-frame + Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattatttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13025 JY8QFUQ01CGZWG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame - ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtactaatacgggggggactgacacagcctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13026 JY8QFUQ01C2DJG productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 951 92.73 204/220 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARRGSYGSGSYYPW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggtggcgccatcagcagtaatagttactactgggactggatccgccagcccccagggaaggggctggagtggattgggagtatgttttatactggggtcaccttctacaacccgtccctcaagagtcgagttaacatttccgtggacacgtccaagagccagttctccctgaggctgagctctgtgaccgccgcagacacggctgtgtatcactgtgcgagacgtggttcctatggttcggggagttattatccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13027 JY8QFUQ01B3M80 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 645 83.15 153/184 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD4-11*01 ORF 3 X 8 X X.8.X [X.15.38.11] DSRNPRV# out-of-frame - Low V-REGION identity (83,15% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggggtccgccaggctccagggaaggggctggagtgggtctcagggctttgtggaagtgctcctaccacacactacgcagactccgtgaagggccggttcagcatctccagagacctctccaagaatgttctgtttctgcaaacgagcagcctgagagccgaggacacgaccgttttttctgactccagaaatcccagggtaggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13028 JY8QFUQ01CDGF0 No results +13029 JY8QFUQ01BCMK8 No results +13030 JY8QFUQ01CXEJW unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CTKDTFWER#DYW out-of-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgttttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13031 JY8QFUQ01A79R5 productive Homsap IGHV3-9*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + ctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13032 JY8QFUQ01CTWUZ productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 896 90.37 197/218 nt 89.45 195/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-9*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARGGVDILTGFYDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'AG' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); gttctggatacagctttggcaccgcctggctcggctgggtgcgccagacgcccgggaaaAGgccctggagtggatggGggaccatccatcctgctgactctgatacaaaatacagcccgtccttccagggccaagtcaccatctcggtcgacaggtccatcaacaccgcctacctgcagtggagcagcctggaggcctcggacaccgccatgtatttctgtgcgcggggaggagtcgatattttgactggtttctatgatgctttcgatatctggggccaagggaccatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13033 JY8QFUQ01CWYEB No results +13034 JY8QFUQ01CAFR8 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 894 88.79 198/223 nt 87.44 195/223 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD6-19*01 F 3 10 7 X 10.7.X [2.17.38.11] CTNDHSMAVSAKHAFDV## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); tgtctctggtgcctccGatgagcaCgtagtgcatactactggggctgggtccgccagaAcccccgggaaggggccggagtggattgggagtgtctactatggtgggagcacctactacaacccgtccctcaagagtcgggcctccatttctgtcgacacgtccaggaacgagttctccctgaggctgaactctgtgaccgccacagacacggctatgtattactgcacgaacgaccattcaatggcagtctctgctaagcatgcttttgatgtttgggggtccagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13035 JY8QFUQ01B2QJ5 No results +13036 JY8QFUQ01CR0DV productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13037 JY8QFUQ01BE590 productive (see comment) Homsap IGHV2-5*02 F, or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F (see comment) 881 84.77 206/243 nt 84.36 205/243 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 3 10 7 11 10.7.11 [9.17.38.11] CAHFGPQEHFDFW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,77% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 93 of V-REGION: 'CG' (2 nucleotides at position 208 to 209 in the user submitted sequence), (cause frameshift); accctcaccctgacctgcgacttctctggattctcactcagcaccaatggaatgggtgtgggttggatccgccagcccccgggagaggccccagactggctcgctctcatttattgggatgatgataagcgataccggccatccctagagagtagactcaccatcaccaaggacatctccacaaaccaggtggtccttagaatgaccCGacatggggcccctnagacacagccacatatttctgtgcacactttggaccacaggagcacttcgacttttggggccagggaatcctggtcactgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13038 JY8QFUQ01BZLGF unknown (see comment) Homsap IGHV4-61*02 F 884 89.14 197/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc +13039 JY8QFUQ01BAFYU No results +13040 JY8QFUQ01DGAGY No results +13041 JY8QFUQ01AWE3U productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13042 JY8QFUQ01BJR0T productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 869 88.99 194/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CAKDRLDSSGHYYHGVYYFGMDVW in-frame + cctctggatttagttttgaaaactatggcatgcattgggtccgccaggctccaggcaagggcctggaatgggtggcggttatatcatatgatgcaagtaacaaatattatgcagacgccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatcttcaaatgatcggcctgagagctgaggacacggctaaatactactgtgcgaaagatcgccttgacagcagtggtcattactaccacggggtctactacttcggaatggacgtctggggcccagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactca +13043 JY8QFUQ01CT5TN unknown (see comment) Homsap IGHV3-7*03 F (see comment) 208 54.79 120/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (54,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13044 JY8QFUQ01DL2SK productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 626 76.15 166/218 nt 75.23 164/218 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIVREGLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (76,15% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 38 of V-REGION: 'TGG' (3 nucleotides at position 31 to 33 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tgtctggtggctccatcgccacttatcgatTGGgtggaacttgggtccgccagaAcccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13045 JY8QFUQ01DAD3P productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 930 91.03 203/223 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 7 17 8.7.17 [4.17.38.11] CARDSGSSEYTRYDAQDVW in-frame + ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttgccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgt +13046 JY8QFUQ01DXGMS productive (see comment) Homsap IGHV4-59*03 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD3-22*01 F 3 8 7 17 8.7.17 [1.17.38.11] CARDQGVVANYYYYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtgattactactggaactggatccggcagcccccagGggaagggactggagtggattgggtatgtctatcacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgttcaagaaccaattatccctgaaggtgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagatcaaggcgtcgtggctaattactactactacggtatggacgtctggggccaaggggccacggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgtctgcctggtccagggcttcttccccccg +13047 JY8QFUQ01C5RV8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcacttttaggagtcatatgatgagttgggtccgccagactccagggaaggggctggaatgggtctcaagtattcgagccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaactccaagaacacgatgtatttgcaaatgcacagcctgagagtcgacgacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggcccagggagccctggtctccgtctgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaaccgtggtcatcgcctgcctcgtccagggcttcttccccca +13048 JY8QFUQ01CB45P productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 879 88.64 195/220 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-19*01 F 2 10 7 16 10.7.16 [1.17.38.11] CTNDHSMAVSAKHAFDVW in-frame + ctctggtgcctccatgagcagtagtgcatactactggggctgggtccgccagacccccgggaaggggccggagtggattgggagtgtctactatggtgggagcacctactacaacccgtccctcaagagtcgggcctccatttctgtcgacacgtccaggaacgagttctccctgaggctgaactctgtgaccgccacagacacggctatgtattactgcacgaacgaccattcaatggcagtctctgctaagcatgcttttgatgtttggggtccagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13049 JY8QFUQ01BDS19 productive Homsap IGHV3-72*01 F 876 88.34 197/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame - ctctgggtttacctttagcaactttgccatggcttgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13050 JY8QFUQ01ACXCD No results +13051 JY8QFUQ01A02GN unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +13052 JY8QFUQ01BGOHU productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13053 JY8QFUQ01BLEOZ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13054 JY8QFUQ01A9DGQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13055 JY8QFUQ01AIGXY productive (see comment) Homsap IGHV3-7*01 F 963 94.01 204/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [2.16.38.11] CATDDSNGWDEVADYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 128 to 128 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 49 of V-REGION: 2 nucleotides (from position 63 in the user submitted sequence), (cause frameshift) acctctggattGcacctttagtaaccattggatgaactgggtccgccaggctccagggaagggctgagtgggtggccaacataatgccagatggaggtgagaaAattctatgtggactctgtgaaggGgccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13056 JY8QFUQ01C6FU9 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 766 83.56 183/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Low V-REGION identity (83,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13057 JY8QFUQ01B0JWX productive Homsap IGHV4-61*02 F (see comment) 677 78.73 174/221 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARDRRRSIAGARHFDSW in-frame - Low V-REGION identity (78,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggccccaccatcgatgatggtgatttgtggacctggatccggcagcccgccggcaagggactggaatggatcggttatgtctatgatgggcggggcaccaactccaacccctccctccggagtcgcgttaccctgtcacaagacacctcaaacaatcagttcttcttgaggttgaagtctgtgaccgcctcagacacggccgtctattactgtgcgcgagaccgccgtaggtcgattgccggagcgagacactttgactcctggggccagggaatcctggtcaccgtcgccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13058 JY8QFUQ01CTHRK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARGPRSRGYGMDVW in-frame - agcctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13059 JY8QFUQ01AXE56 productive (see comment) Homsap IGHV3-9*01 F (see comment) 778 84.72 183/216 nt 84.26 182/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.37.11] CVKDMVAGQGLLSRFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 111 in the user submitted sequence), (cause frameshift) ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatgggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13060 JY8QFUQ01BI6RE unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt 87.1 189/217 nt Homsap IGHJ5*01 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.16.38.11] CARDGDYYDSSGNFLGHSFDI## out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cgtctggattcacctttagtgattatgccttgagctgggtccgccagactcccgggaagggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacgactccaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcgagagatggagattattatgatagtagtggtaatttcctgggacattcttttgatatctgggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13061 JY8QFUQ01CM936 No results +13062 JY8QFUQ01AU7DL No results +13063 JY8QFUQ01DH1JU productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ6*02 F (see comment) 188 78.69 48/61 nt Homsap IGHD3-16*01 F 3 8 7 12 8.7.12 [1.17.38.11] CAREGGRGYDMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 103 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtatctatgccatgacctgggtccgccaggctccagggaaggggctggagtggatttcatttatcactgataggggtagtaccaatactacgcagactctgtgaagggccgattcaccgtctccagggaccaagccaagaactcactgtatctacaaatgaacaacctgggagtcgaggacacggctgtgtattattgtgcgagagaggggggacgtggctacgatatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca +13064 JY8QFUQ01BR9V1 productive Homsap IGHV3-11*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame + ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggctttcatacattagtggtagtggaactaccatatcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaggaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgaggcgggtgtggggatatagttatggttccgtttcgtactactttgagtactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagcatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13065 JY8QFUQ01CEG6J productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CATISDYRFEFW in-frame + ctctggattcacctttagtggctattggatgagttgggtccgccaggctccggggaagggtctggagtgggtggccaacatagagaaagatggaagtgacataaagtatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtctctgcaaatgaacagcctgagagccgacgacacggctatttattactgtgcgaccattagtgactaccgatttgaattctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13066 JY8QFUQ01CF3IX productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactca +13067 JY8QFUQ01AC5UE No results +13068 JY8QFUQ01CVFZR unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13069 JY8QFUQ01CDO5X unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1011 97.2 208/214 nt Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [0.17.38.11] CARGQQLRDFDY# out-of-frame + tggatacaccttcaccagctactatttgcactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcgaggggacagcagcttcgagactttgactactggggccagggaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13070 JY8QFUQ01BI3SN productive Homsap IGHV3-11*01 F 954 93.55 203/217 nt Homsap IGHJ2*01 F (see comment) 211 88.68 47/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CADIRLGDWCFDIW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtgaccactacatgagttggatccgccaggctccagggaaggggctggagtggatttcatatattagtactagtggtaatatgatttattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaactcactgtatctgcagatgaacagcctgagagccgaggacacggccgtctatttctgtgccgatataagactgggtgactggtgcttcgatatctggggccggggcaccctggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13071 JY8QFUQ01C49B2 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 2 8 7 X 8.7.X [1.17.38.11] CARAPRTATLLDP#W out-of-frame + in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tctctggcgactccatcagtggtcactactggagctggatcaggcagccCcccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaaccCcctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgaccccgtggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13072 JY8QFUQ01DDSRU unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ3*02 F (see comment) 124 72.0 36/50 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [0.17.38.11] CARELGGSGTCGFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); tggatacaccttcaccaggcactatatgcactgggtgcgacaggcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggGggcagagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactgggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccc +13073 JY8QFUQ01BI2G2 productive (see comment) Homsap IGHV3-7*01 F 1012 96.76 209/216 nt 96.3 208/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); tctggattcaGcctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13074 JY8QFUQ01B6L9D productive (see comment) Homsap IGHV3-48*01 F (see comment) 744 83.89 177/211 nt 82.94 175/211 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [0.17.38.11] CSRDGRRGYDLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,89% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 80 in the user submitted sequence), (do not cause frameshift) tggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtGgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13075 JY8QFUQ01DNLTG No results +13076 JY8QFUQ01CWWNH productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaaggggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13077 JY8QFUQ01B82C5 unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYD*GEYAMDVW in-frame + stop codons gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactagggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13078 JY8QFUQ01CF0TC productive Homsap IGHV3-66*02 F 894 91.12 195/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 7 13 8.7.13 [1.17.38.11] CASVGVGATVAFQYW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattcaccgtcagtgatagttacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcgattctttataggggaggtaccacatattatgccgactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctatatcttcaaatgaacaccctgagaggtgaggacacggctctatattactgtgcgagcgtcggagtgggagctacagtcgcctttcaatactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13079 JY8QFUQ01DHNOA No results +13080 JY8QFUQ01AZFMI productive (see comment) Homsap IGHV4-39*03 F 929 91.36 201/220 nt 90.91 200/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcCccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgt +13081 JY8QFUQ01DQYPT No results +13082 JY8QFUQ01DSMPJ No results +13083 JY8QFUQ01CP7W8 No results +13084 JY8QFUQ01CWMFJ No results +13085 JY8QFUQ01CDQ8D productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 872 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttatgccatgagttgggnccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13086 JY8QFUQ01ASJZS productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13087 JY8QFUQ01A1EAJ productive (see comment) Homsap IGHV3-7*03 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGcctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13088 JY8QFUQ01DB22E productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.17.38.11] CARGEMTAEYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtgttCaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +13089 JY8QFUQ01BCH7Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13090 JY8QFUQ01CVYUM productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 989 93.75 210/224 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 2 8 10 14 8.10.14 [1.17.38.11] CTTDPRYFWGSGFDYW in-frame - cctctggattccctttcagcaacacctacatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaaactgatggtgggacaatagaatacgctgcacccgtgaaaggcagattaaccatatcaagagacgattcaaaaaacacgctgtatctgcatatgagcagcctgaagatcgaggacacagccgtgtattactgtaccaccgatccccgttacttttgggggagcgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13091 JY8QFUQ01DB3M9 No results +13092 JY8QFUQ01C0IFS No results +13093 JY8QFUQ01CK6XV productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 7 22 8.7.22 [1.17.38.11] CARVKTDYYDSSGSYLPLYFFDYW in-frame + tctctggtgactccttcagaactcactactggagttggattcgacagcccccggggaggagattggaatggattggcaatatatattatattgggaccaccaactacaacccctccctcaagagtcgagtcaccatgttagtggacacgtccaagaagcagttctccctgagactgagttctgtgaccgctgcggacacggccatgtattattgtgcgagggtcaagactgattattatgatagtagtggttcttacctgcccctgtatttctttgattactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +13094 JY8QFUQ01A3NWZ unknown (see comment) Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13095 JY8QFUQ01AJOJR unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRGGSQWGLQVG#FDYW out-of-frame - stop codons ctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgacgacacggctgtttactactgtgtgagaggggggagtcagtggggccttcaggtgggggtttgactactggggccagggaaccctggccaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13096 JY8QFUQ01AQPJX No results +13097 JY8QFUQ01B2B76 No results +13098 JY8QFUQ01B0M02 No results +13099 JY8QFUQ01DS4IG unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 994 93.78 211/225 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 X 8.10.X [2.17.38.11] CTTGGWN*L##W out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) acctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcgaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacaggggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13100 JY8QFUQ01BVEA2 productive (see comment) Homsap IGHV3-7*01 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.16.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift) ctctggattcagctttagttattattggatgagctgggtcgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13101 JY8QFUQ01AIAUO unproductive (see comment) Homsap IGHV3-7*01 F 816 85.91 189/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARGSYYYYDTNGDYW in-frame - stop codons ctctggatttgacctttgacaaattattgggatgagctgggtccgccaggctccagggagggggctggagtgggtggccagcgtaaaacaagatggaggtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggtcctactattattatgatactaatggcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13102 JY8QFUQ01DI8RP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 868 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.37.11] CAKDASRYYYNSYCDNW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 213 in the user submitted sequence), (cause frameshift) ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttattttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13103 JY8QFUQ01CP5IA productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [2.16.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gtctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaaggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13104 JY8QFUQ01AQZCF productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD4-17*01 F 2 8 7 18 8.7.18 [1.16.38.11] CASVVTINDNGDYTWAFDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) tctatggtgggtccttcaataattacttctggacctggatccgccagtcccagggaaggggccggagtggattggggaaatcaatcatagtggtagcaccaactacaatccgtccctcaagagtcgagtcaccatctcaatagacacgtccaagatccagttctccctgcagctgagctctgtgaccgccgcggacacggctgtctattactgtgccagtgtagtgaccattaatgacaacggtgactacacgtgggcttttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccacccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13105 JY8QFUQ01BN4SH No results +13106 JY8QFUQ01CGSXJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13107 JY8QFUQ01CPWQZ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGG# out-of-frame + ttctggattcacttttagcagtcatatgatgagttgggtccgccaggctccagggaagggactggaatgggtctcaagtattcgtgccagtggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgctgtatttgcaaatgtacagcctgagagtcgaggacacggccttatattactgtatgaacgaactcggatattgtagtggtgggggggccagggagccctggtcaccgtctcctcaggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13108 JY8QFUQ01CYV8D productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - ctctggattccccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaggggccgattcaccatctccagagacaacgccaggaactcattgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13109 JY8QFUQ01AFQ4V unproductive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGY*GIYFFDYW in-frame + stop codons ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttactgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttgccccctggcgccctcgctccaggagcacctccgacgagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13110 JY8QFUQ01B56AV unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 454 72.63 130/179 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (72,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13111 JY8QFUQ01A0R5L productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 848 91.13 185/203 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 4 8 11 4.8.11 [X.17.38.11] CARFGPLTRPDYW in-frame - tatcaacttatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13112 JY8QFUQ01C91GT unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [1.17.38.11] CANASPLYNWN#YFYYYGMDVW out-of-frame + cctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctcccccctgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca +13113 JY8QFUQ01A4HOH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13114 JY8QFUQ01C12XQ unproductive Homsap IGHV3-9*01 F 1008 96.31 209/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGIAVAASHESTFRLL# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttgatgattttgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaggatagtctatgcggactctgtgaagggccgattcaccatctccagagacaacgcccagaactccctgtatctgcaaatgaacagtctgggtactgaggacacggccttgtattactgtgcaaggggtatagcagtggctgcctcccacgagtcgacttttcgactactggggcccaggggaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13115 JY8QFUQ01DA1KP productive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 808 86.85 185/213 nt 85.92 183/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 7 12 8.7.12 [0.17.38.11] CARRSTSGDKFDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 86 in the user submitted sequence), (cause frameshift) tggagggaacttcaacaattatggtttcagctgggtgcgacaggcccctggacaaggccttgagtggatgGggagaaatcatcccttttttggaacatcaaaatatacacagaaattccagggcagactctccattaccgcggacgaatccacgagcacagcctttatggacttgagtggcctgagatctgaggacacggccgtctattattgtgcgagaaggtctactagtggggataaatttgacttctggggccagggaagccaggtcaccgtctcctcagcctccaccaagggcccaatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaacctcag +13116 JY8QFUQ01A4AB0 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13117 JY8QFUQ01B190C No results +13118 JY8QFUQ01C91ZM unproductive Homsap IGHV4-34*10 F 818 86.98 187/215 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD4-23*01 ORF 1 8 7 X 8.7.X [1.17.38.11] CARNTNYGGNSGDYFDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggcccaagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13119 JY8QFUQ01DIM4J productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 789 84.55 186/220 nt 83.64 184/220 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD3-16*01 F 2 8 10 13 8.10.13 [0.16.38.11] CSTGGPNGYESTYPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) ctggattGcaccttcaatatcaagtggatgagttgggtccgccaggctccgggaaggggctggagtgggttggccgcatcaagagcacctctgatggtgggacaacagactccattgcacacgtcaaagacagattcatcatctcaagagatgattcaagaaatacactgtacttacaaatgaacaacctgagagtcgaggatacaggcgtctattattgttccacaggagggccaaatggttatgagtctacctatccctggggcccgggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13120 JY8QFUQ01BHB9O unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ6*02 F 130 67.74 42/62 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKYVEGWS*YGGLL##SYAMDVW out-of-frame + stop codons in FR2-IMGT at codon 51 of V-REGION: 'AG' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift); ttctggattcgcctttagccgttatgccatgacttgggtccgccagactccagggaggggcgtggaAGgtgggtctcaggtctcagtggtagtggtgatagcacatactactcaaactccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggaggggtggtcatgatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13121 JY8QFUQ01C3EMZ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +13122 JY8QFUQ01CNC9O productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13123 JY8QFUQ01BWY7M productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-1*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKEEGTTGVYYVDHW in-frame - tctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtactactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13124 JY8QFUQ01BT1EX No results +13125 JY8QFUQ01CQQFU unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*03 F (see comment) 123 72.92 35/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRRGMVAGRYDAFDI# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctgggccgagggactatggtcaccgtctctccagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13126 JY8QFUQ01C157F unproductive Homsap IGHV4-61*02 F 888 89.55 197/220 nt 89.09 196/220 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 10 7 X 10.7.X [1.17.38.11] CARQGDSSGPWNDY## out-of-frame + in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatTttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13127 JY8QFUQ01AX6P6 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 960 93.18 205/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactggtgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13128 JY8QFUQ01CEBII unknown (see comment) Homsap IGHV1-2*02 F 487 86.72 111/128 nt 8 8 X 8.8.X [0.17.9.X] null + No rearrangement found tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcaggg +13129 JY8QFUQ01CGQ43 unproductive (see comment) Homsap IGHV4-59*03 F 915 92.89 196/211 nt 91.94 194/211 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 X 8.7.X [0.17.38.11] CARGHF***WLFQP#LDHW out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'GC' (2 nucleotides at position 44 to 45 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 88 to 93 in the user submitted sequence), (do not cause frameshift); tggtgtctccatcagtagtttctactggagttggatgaggcagGCcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacatttttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13130 JY8QFUQ01AMPPP productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13131 JY8QFUQ01CPBR4 productive Homsap IGHV3-7*03 F 837 87.56 190/217 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcacttttagtgactattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13132 JY8QFUQ01DTGK2 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKAYDDVLTSYYIAAFIDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgccatgcattgggtccgccaggctccaggcaaggggccggagtgggtggcagttatatcatatgatggaagtcataaagactatgcagcctccgtgaagggccgattcaccatctccagagacaattccaagagtacgttgtatctgcaaatgaacagcctgagacctgaggacacggctttatattcctgtgcgaaggcatatgacgatgttttgacttcttattacatagcagcttttattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13133 JY8QFUQ01CCCXG productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtacatactggatgcactgggtccgccCaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13134 JY8QFUQ01ABG0T productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 836 87.91 189/215 nt 86.98 187/215 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 7 8 13 7.8.13 [1.16.38.11] CVSDRELHYQHLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift) gtctggattcaactcaatagttttggcatgcactgggtcgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacaacggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13135 JY8QFUQ01BI9PN productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13136 JY8QFUQ01BALK4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKKLGGRRWL#WYFDFW out-of-frame + in CDR2-IMGT at codon 58 of V-REGION: 'ATG' (3 nucleotides at position 88 to 90 in the user submitted sequence), (do not cause frameshift); cctctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattactaATGgtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttatttctgtgcgaaaaaattagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13137 JY8QFUQ01AGZEC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13138 JY8QFUQ01CIXDK productive Homsap IGHV3-11*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARVKYSSSWSSILDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaacttcggtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtttcattcattagtagtcctggtatcaggagtttctacgcagactctgtgaagggccgattcactatttccagggacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgaggacacggccatatattactgtgcgagagtgaaatatagcagcagctggtcctcaatccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13139 JY8QFUQ01AMY1J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgt +13140 JY8QFUQ01B5AY8 productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13141 JY8QFUQ01BIQEK productive Homsap IGHV3-7*01 F 918 91.24 198/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 2 8 8 18 8.8.18 [1.17.38.11] CSRHGGYTRLYNQNVYLDYW in-frame - ctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaaaataaacccagacggaagtgagaaatactatgtggactctgtgaagggccgattcaccacctccagagacaactctagaaactcgctgtgtctgcaaatggacagcctgagagccgaggacacggctgtgtattactgctcgagacatggaggttacacgagactctacaatcaaaatgtctaccttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13142 JY8QFUQ01DM5WF productive Homsap IGHV1-8*01 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARVWGVAFTGVWNYW in-frame - tggatacaccttcgccaattttgatatccactgggtgcgacaggccactggacaagggcttgagtggctgggatggatgcaccctaatagtggtaatacagtctatgcacagaagttccagggcagagtcaccatgaccaggaacacctccataagcacagcctacatggagctgagcagcctgagatctgaagacacggccatatattactgtgcgagagtctggggagtagcattcactggggtgtggaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13143 JY8QFUQ01AZH44 No results +13144 JY8QFUQ01C8AT8 unknown (see comment) Homsap IGHV1-2*01 F, or Homsap IGHV1-2*02 F or Homsap IGHV1-2*04 F or Homsap IGHV1-2*05 F or Homsap IGHV1-46*01 F or Homsap IGHV1-46*03 F (see comment) 259 69.91 79/113 nt 8 8 X 8.8.X [0.17.4.X] null - No rearrangement found Low V-REGION identity (69,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcaccgaccactatctgcactgggtccgacaggcccctggacaagggcttgagtggatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13145 JY8QFUQ01CUK8E productive (see comment) Homsap IGHV4-61*02 F 947 92.31 204/221 nt 91.86 203/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcGatcgcacgcaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13146 JY8QFUQ01AV2DS No results +13147 JY8QFUQ01BLJZD productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13148 JY8QFUQ01DASRD No results +13149 JY8QFUQ01DOPR7 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13150 JY8QFUQ01BYO1I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD3-10*01 F 2 8 8 21 8.8.21 [1.17.38.11] CARVMREHYYGAGNYPWGEWKSG in-frame + ctctggattcacctttaacaactatgccatgacctgggtccgccaggctccggggaaggggctggagtgggtctcagctatcagtggcagtggcggtaccacttactacgcagactccgtgcagggccgcttcaccatttccagagacaatcacgaaaacaccctgtatctggaaatgagtagcctgagagccgaggacgcggccgtctattactgtgcgagagtgatgagggaacattattatggagcggggaattatccctggggggaatggaagtctggggccaggggaccacggtgcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +13151 JY8QFUQ01AQOEM productive Homsap IGHV3-48*02 F 896 90.37 197/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDHIWAFDFW in-frame + cctctggattcaccttcagtgactatagcatgaactgggtccgccagactccagggaagggggtggagtggatttcatacatcggccgtggtggtgatgggatatactacgcagactctgtgaagggccgaatcaccatctccagagacaatgccaagaactcactttttctgcaaatgaacaccctgagagacgacgacacggctgtgtattactgtgcgagagaccacatttgggcttttgatttctggggccaagggacaaaggttaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13152 JY8QFUQ01ACD8U productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1001 95.02 210/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 2 10 7 11 10.7.11 [1.17.38.11] CAGREVSGPFDFW in-frame - tctctggtggctccatcaagaggagtagttattactggggctggatccgccagcccccagggaaggggctggagtggattgggactatctattatagtgggagcacgtactacaactcgtccctcgagagtcgagtcaccatgtccgcagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtctattactgtgcgggacgagaagtgtcaggcccgtttgacttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13153 JY8QFUQ01AY96B productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13154 JY8QFUQ01CBKYC productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13155 JY8QFUQ01DJGC1 productive Homsap IGHV3-7*01 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [2.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame - gcctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13156 JY8QFUQ01AIR5Z unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGL*QWL##DFDCW out-of-frame + stop codons cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggttatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13157 JY8QFUQ01CK3ME No results +13158 JY8QFUQ01BTBFG unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame + ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +13159 JY8QFUQ01AWJG8 productive Homsap IGHV4-61*02 F 857 87.78 194/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 11 10.7.11 [1.17.38.11] CARSGWDNQFDFW in-frame - tctctggtgtcgccaccagtagtggcacttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaacccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgcttcaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13160 JY8QFUQ01C117N No results +13161 JY8QFUQ01DU9XY unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt 86.64 188/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKQKR*LW#YYFDQW out-of-frame + stop codons in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); ctctggattcacctTttagtaaccattggatgaactgggtccgccaggctccaggaaaggggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaaacgatagttatggatactactttgaccagtggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca +13162 JY8QFUQ01CCDYP No results +13163 JY8QFUQ01CBH7Q No results +13164 JY8QFUQ01BSBL1 productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame - ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcgggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13165 JY8QFUQ01COT6C unproductive (see comment) Homsap IGHV4-39*02 F 912 90.13 201/223 nt 89.69 200/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 10 7 X 10.7.X [2.17.38.11] CARGHTNFWSGYSG#DYW out-of-frame - stop codons in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); tctctgggtgactcccatttccagtactagttattactggggctgggtccgccagcccccagggaaagggctggagtggattCgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaggccatacgaatttttggagtggttactcgggatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13166 JY8QFUQ01BA5IW No results +13167 JY8QFUQ01B5ITM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13168 JY8QFUQ01AQNL3 unproductive (see comment) Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGAG*PFF##YYSGLDVW out-of-frame + stop codons ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggcagggtgacccttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13169 JY8QFUQ01B2N1Y No results +13170 JY8QFUQ01AY9NB productive Homsap IGHV3-30*10 F 896 90.37 197/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 3 8 8 19 8.8.19 [1.17.38.11] CARDVTTTVVVVVTLGAFDLW in-frame - cctctggattcagcttcactaaatatcctatacactgggtccgccaggctccaggcaagggactagagtgggtggcacttatatcatttgatggaactaataaatactacacagactccgtgaagggccgattcaccatctccagagacaattccaagaacacagtctttctgcagatgaacagtctgacaactgaagacacggctgcttattactgtgcgagagatgtgactactacggtggtagtagtcgtcacacttggagcttttgatctctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +13171 JY8QFUQ01CY32W unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F (see comment) 644 77.06 168/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (77,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctcgggattcaacttcaagtccaacaccatgaattgggtccgccaggctccagggaaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13172 JY8QFUQ01B4K2Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13173 JY8QFUQ01CKRGV productive Homsap IGHV3-9*01 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [1.17.38.11] CAKATTAWYSGGLDVW in-frame + cctctggattcaactttgatgattacggcatgcactgggtccggcaacgcccagggatgggcctggagtgggtcgcaggtattagttataataatggccacaaagaatatgcggactctgtgaggggccgattcaccatctctagagacaacgccaggaagtccctgtatctgcagatggacagtctgagagttgaggacacggccttgtattattgtgcaaaggctacaactgcctggtattcaggcggtctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13174 JY8QFUQ01DJDE8 No results +13175 JY8QFUQ01A0OC8 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 972 94.47 205/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [1.17.37.11] CAKSPSQVGYYLDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 77 of V-REGION: 1 nucleotides (from position 137 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtacctTttggcatgcactgggtccgccaggctcccggcAaaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcacatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13176 JY8QFUQ01DKGHA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1025 97.67 210/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CAKGPHQYYFDYW in-frame + ctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13177 JY8QFUQ01AVB4I productive Homsap IGHV3-7*01 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-2*01 F 2 8 8 9 8.8.9 [1.17.38.11] CATRSRSPANW in-frame + ctctggattcagttttagtacctattggatgagctgggtccgccaggctccagggaaggggctggaatgggtggccaccataaacgaggatggaagtgacagaacctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaaaaattcattgtatctacaaatgaatagcctgagaaccgacgacacggctcgatattactgtgcgacgcgtagtagaagtccggcgaactggggccagggaagcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +13178 JY8QFUQ01CALIR No results +13179 JY8QFUQ01BZ7VC unknown (see comment) Homsap IGHV3-11*01 F (see comment) 458 67.91 146/215 nt 8 8 X 8.8.X [0.17.38.X] null - No rearrangement found Low V-REGION identity (67,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcatggtatacctggcagactccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13180 JY8QFUQ01AWJE7 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 887 89.91 196/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); cctctggattctccgtcagtaAgttactggatgcactgggtccgccaggctccaggggaggggctggGagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13181 JY8QFUQ01A6Q87 productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13182 JY8QFUQ01BESKE productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13183 JY8QFUQ01AX3ZS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13184 JY8QFUQ01DIJLD productive (see comment) Homsap IGHV4-4*07 F 827 87.44 188/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [2.17.37.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 212 in the user submitted sequence), (cause frameshift) gtctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgCaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtattttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13185 JY8QFUQ01AD5UE productive Homsap IGHV3-74*03 F 914 91.28 199/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKVDSDGWHGTIDRW in-frame + cctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggatagcgatggctggcacggaacaatagaccgctggggccagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13186 JY8QFUQ01A6B9M productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13187 JY8QFUQ01BB385 unproductive (see comment) Homsap IGHV3-72*01 F 894 89.24 199/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 1 8 10 X 8.10.X [1.17.38.11] CAVAAPPL#DGW out-of-frame + stop codons ctctggattcaccttaagtgacttctacatggactggctccgccaggctccagggaaggggctggagtgggttggtcgcagtagaaacaaagctaatggttacagtacacaattcgccgcatctgtgatgggcagattcaccatctcaagagatgactcaaagaatttactatatctacaaatgagcagcctgaaaaccgaggacacggccatttattactgtgctgtcgcagcccccccgttatgacggctggggccagggaaccctggtcatcgtctcctcagcatcccgaccagcccgaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccg +13188 JY8QFUQ01DO5KZ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 849 88.79 190/214 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARVDFYGSSKYKGFDPW in-frame - ctctggtaactccatcacagattattactggagctggctccggcagtctccagggaagggactggagtggattggaaatgtcttttacagtgggagagccaactacaacccctccctcaagagtcgagtcaccatatcagtagccacgtccaggaaccagttctccctgaagctcaggtctgtgaccactgcggacacggccatatattattgtgcgagagttgatttctatggttcgagtaaatataaggggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13189 JY8QFUQ01BYAQ8 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 960 93.18 205/220 nt 91.82 202/220 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARPFSGRWCFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaAaaggggccggtgtgggtctcacaaattCaaaagtgatgggagtaCccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtgtgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13190 JY8QFUQ01AJO76 productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcagtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13191 JY8QFUQ01CU0D5 productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13192 JY8QFUQ01CRR42 productive Homsap IGHV3-7*01 F 952 94.37 201/213 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [X.17.38.11] CAKDGYYYYHSGMDVW in-frame - ggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattattgtgcgaaagacggctattattattatcacagcggtatggacgtctggggccaagggaccacggtcatcgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13193 JY8QFUQ01AP0TZ productive Homsap IGHV3-9*01 F 958 93.52 202/216 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDAMGGAGDWAAFGIW in-frame + tctggcttcatctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagcgctaccatagaatatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctggaaatcaacagtctgagacctgaagacacggccttatactactgcgcaaaagatgcgatgggaggagctggtgattgggctgcttttggtatctggggccaggggacaatggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgctggtccagggcttcttccc +13194 JY8QFUQ01BEBP0 No results +13195 JY8QFUQ01BV9YG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccatcaagggccccatcggtcttccccccttggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13196 JY8QFUQ01AB5DG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + cctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactca +13197 JY8QFUQ01DRW2W unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-3*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRVGAPYYDFWSGYQTNWF#PW out-of-frame - in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagcGtactggatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgcaagtactacttccatacattatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggcgccatattacgatttctggagtggctatcagactaactggttcgaccctggggccagggaactctggtcaccgttacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13198 JY8QFUQ01AITV3 productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1039 96.0 216/225 nt 95.56 215/225 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 10 9 8.10.9 [2.17.38.11] CTRGGYSYAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); acttctggattcacctttggtgattatgctatgagttggttccgccaggctccagggaaggGggctggagtgggtaggtttcattggaggcagagctcatggtggggcaacagaatacgccgcgtctgtgaaaggcagattcatcatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattattgtactagagggggatacagttatgcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13199 JY8QFUQ01ANXRG productive Homsap IGHV3-74*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13200 JY8QFUQ01DOYIV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARGPRSRGYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcaacGaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13201 JY8QFUQ01AEKPA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 841 87.5 189/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13202 JY8QFUQ01BPUYM unknown (see comment) Homsap IGHV3-11*01 F (see comment) 633 77.1 165/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BPUYM ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (77,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13203 JY8QFUQ01A3IWM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 979 95.77 204/213 nt 95.31 203/213 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [0.17.37.11] CAKDGARGGGSCFNSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 173 in the user submitted sequence), (cause frameshift) tggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13204 JY8QFUQ01DH3WS productive Homsap IGHV3-11*01 F 955 93.15 204/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [2.17.38.11] CVRRVWGYSYGSVSYYFDYW in-frame - gcctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcatacattagtgggagtgcgactaccatatcctacgcagactttgcgaagggccgattcaccatctccagggacaacgccaagaactcggtgtatctgcaaatgaacagcctgagagccgaggacacggccacgtattattgtgtgaggcgggtctggggatacagttatggttccgtttcgtattacttcgactactggggccagggaatcccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13205 JY8QFUQ01BU6WY productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagttataGgcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13206 JY8QFUQ01COFUI No results +13207 JY8QFUQ01BUNIG productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKNNNDFGDYDWFDPW in-frame + tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactgggggcaccgactccaacccctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +13208 JY8QFUQ01A2PDE productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13209 JY8QFUQ01B7HB0 No results +13210 JY8QFUQ01B62DJ unproductive (see comment) Homsap IGHV4-61*02 F 951 92.73 204/220 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + stop codons ctctggtggctccatcaggagtggtagttactactggagctagatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13211 JY8QFUQ01B4WCZ productive Homsap IGHV3-48*01 F 1085 100.0 218/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame - cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13212 JY8QFUQ01CF2KP productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 855 88.48 192/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame + ttctggattcagtcctaccgatttttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13213 JY8QFUQ01AWDF7 No results +13214 JY8QFUQ01BY1KF unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKKTL*FGDLF#YNFDYW out-of-frame + stop codons ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaacattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13215 JY8QFUQ01C3HIA productive Homsap IGHV3-30*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame + ctctggattcaacttcaggacctattctatgcactggctccgccaggctccaggcaagggactagagtgggtatcagttatttcatatgatggaactaagaagaattatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctacaaatggacagcctgagacctgaggacacggctgtgtattactgtgcgagagatgaactgccttgggatacaatagagtattactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +13216 JY8QFUQ01C8XR0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccacaagggccccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactca +13217 JY8QFUQ01BDT1C No results +13218 JY8QFUQ01DE4Y3 productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13219 JY8QFUQ01BZ3OY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CVKDYGNCGGGRCYSIPLDYW in-frame + cctctggatttacctttagccgctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcattattgatgttaattctttcacatactacgcagactctgttcggggccggttcaccgtgtccagagacgattccaagaacacggtatatctgcaaatgaacagtttgagacccgacgacacggccgtttattattgtgtgaaagattacggtaactgtggtggtggtcgctgctattcgattccccttgactactggggccggggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13220 JY8QFUQ01B3EPF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13221 JY8QFUQ01A907V No results +13222 JY8QFUQ01CSN3B unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ6*01 F (see comment) 94 60.32 38/63 nt 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFGRT (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttggacgaacctggggccaggaacctggtcnccgtctcctcagcctccagccaaggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13223 JY8QFUQ01BWLOU productive (see comment) Homsap IGHV4-39*03 F 929 91.36 201/220 nt 90.91 200/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcCccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13224 JY8QFUQ01CAMSA unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 977 94.5 206/218 nt Homsap IGHJ3*01 F (see comment) 124 72.0 36/50 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKSPSQVGYYLD#VG out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccggcaaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcaccatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13225 JY8QFUQ01CQ2XD productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 2 8 7 16 8.7.16 [2.17.38.11] CARVDFYGSSKYKGFDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); gtctctggtaactccatcacagattattactggagctggctccggcagtctccagggaagggactggagtggattggaaatgtcCttttacagtgggagagccaactacaacccctccctcaagagtcgagtcaccatatcagtagccacgtccaggaaccagttctccctgaagctcaggtctgtgaccactgcggacacggccatatattattgtgcgagagttgatttctatggttcgagtaaatataaggggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13226 JY8QFUQ01C3IXU No results +13227 JY8QFUQ01AHEF7 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 88.99 194/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CANEVGYCSGR## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacctctatgtcatgcactggttccgGccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaAagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtcggggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcatgcctggtccagggcttcttccccca +13228 JY8QFUQ01CA2ZN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame - tctggattcacctttagcatctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcgactattagtggtagtggaaatagtacataccatgcagactccatgaagggccggttcaccctctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13229 JY8QFUQ01A73LL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKGMGTVVVTNTPLYPFDIW in-frame + cctctggattcaactttgacagcagtgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagccattagtggtcgtgctttcggcacagactacgcagcctctgtgaagggccggttcaccatctccagagacaattccaagaacactctgtatctgcaaatgaacagcctgcgagtcgaggactcggccatatattactgtgcgaaaggcatggggacagtggtggtcactaatactccgttgtatccttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcatctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13230 JY8QFUQ01A7O0L unknown (see comment) Homsap IGHV3-11*01 F (see comment) 757 83.11 182/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (83,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ggctctggattcaccctcagtgactacagtatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatacatcagccgaagtggaagtaatgtggaaactgcggactctgtgaggggccgattcaccgcctccagggacaccgccaataattcactgtttctgcggatgaatagcctgacagtcgaggacacggccctctattactgtgcgagagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13231 JY8QFUQ01AKSKE productive (see comment) Homsap IGHV2-5*02 F 1147 97.12 236/243 nt 96.3 234/243 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 2 10 7 11 10.7.11 [9.16.38.11] CAHRRIRFGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 65 to 65 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 88 in the user submitted sequence), (cause frameshift) acccctcacgctgacctgcaccttctctgggttctcactcagcactggtggagtgggtgtgggcCtggatccgtcagcccccaggaaagccctggagtggcttgcactcatttattgggatgatgataagcgctacagcccatctctgaagagcagactcaccatcaccaaggacacgtccaagaaccaggtggtcctcacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacaggaggatacgattcggctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13232 JY8QFUQ01BALM2 No results +13233 JY8QFUQ01DQ8UA No results +13234 JY8QFUQ01DRKGA No results +13235 JY8QFUQ01BELWX unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 738 82.03 178/217 nt Homsap IGHJ1*01 F (see comment) 28 72.73 8/11 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. gtctgggttctccgtcagtttcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatgccacaaattacgcagactccgtgaagggccggttcaccatctccagagacaactccatgaacacactgtatctgcaaatgaacagcctgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13236 JY8QFUQ01CQ5DQ unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDNYGDY## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13237 JY8QFUQ01DAH2M productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.16.38.11] CARAIGRPFYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcacctttaccaactatgccatgacctgggtccgccaggctccagggaagggctggaatgggtctcaactattagtaatcgtggtactggagtgtactacgcagactccgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13238 JY8QFUQ01DJ4KO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.74 200/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - cctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcattcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13239 JY8QFUQ01CEF1U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13240 JY8QFUQ01B8DED productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARADNYDSLGLKFDPW in-frame + tctctggtgactccatcagtagtaactactggaactggatccggcagcccccagggaagggactggagtggattgggtatatctatcacagtgggagcaccagctacaacccctccctcaggagtcgagtcaccatatcattagacacgtccaagaaccagttctccctgaaactgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggcggataattatgatagtcttgggctgaagttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +13241 JY8QFUQ01AOZQ7 No results +13242 JY8QFUQ01DAF4D productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 804 86.45 185/214 nt 85.51 183/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 7 7 10 7.7.10 [1.17.38.11] CATLRGGTFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 23 in the user submitted sequence), (cause frameshift) tctctggtgcctccatcaggagtattattggagttggatccggcagcccccaggaaagggactggagtggattggttataCttaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13243 JY8QFUQ01CMWHN productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaa +13244 JY8QFUQ01DT743 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 911 90.5 200/221 nt 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagTcccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13245 JY8QFUQ01BZLJJ productive Homsap IGHV1-18*01 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD2-21*02 F 3 8 8 17 8.8.17 [0.17.38.11] CVREESIVVVTGRRGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggcctggagtggatgggatgggtcagcggttataatgataaatccaactatgcacagaagttcaaagacagaattatcatgaccacagacatatcaacgagcacagcctacatggagctgaggagcctgagatctgacgacacggccatgtattattgtgttagagaagagtcaattgtggtggtgaccgggcggcggggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13246 JY8QFUQ01B8OYO unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDLFQVSTTYFDY## out-of-frame + tctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggcccggggaaccctggtcaccgtctcctcagcctccaccaagggccccattcggtcttccccctggcaccctctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13247 JY8QFUQ01BE1GG productive (see comment) Homsap IGHV4-61*02 F (see comment) 654 77.73 171/220 nt 77.27 170/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.16.38.11] CARERDRSIGGAAELDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (77,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift) tctccaatgtacccatcagtcgtggaggttactactggaattggatccggcaggccgccgggaagggctggagtggcttggacgtgttgacagtaatggattcgtcaggtacaattcttccctcaaaagtcgcctttctatgtcactagacacgtccaagaatcagatctccctgatattgaggtctgtgatcgccgcagacacggccgtatatttctgtgcgagggagcgtgataggtcgatcggtggagcggcagaacttgactcctggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +13248 JY8QFUQ01AR58C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13249 JY8QFUQ01B5XE3 productive (see comment) Homsap IGHV4-61*02 F 829 86.76 190/219 nt 86.3 189/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 9 7 15 9.7.15 [1.17.38.11] CARDTGQTYGRGPLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift) ctctggtgcctccataataggggtaattattactggaactggatccggcagcccgccgggaagggcctggaatggattggccgaatctatacaagtgggagcaccatctacaacccctccctcgggggtcgagtcaccatgactgtagacccgtccgagaatcagttcttcctgagactgagttctgtgaccgccgcagacacggccgtttatttttgtgcgagagacactggacaaacctacggtcggggccctttggactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13250 JY8QFUQ01ANW3Z No results +13251 JY8QFUQ01AZLYZ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + cgtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcgggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccttgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +13252 JY8QFUQ01BSPM8 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDNLR*LLG in-frame + stop codons ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataatttacggtgactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13253 JY8QFUQ01A8BQT productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARAKRFWGPPTGMDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagcaaaaaggttctggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +13254 JY8QFUQ01DQMVS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13255 JY8QFUQ01COT7A productive Homsap IGHV3-7*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtctgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13256 JY8QFUQ01ATOXX productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13257 JY8QFUQ01C8QQV unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1115 100.0 224/224 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFFGLL# out-of-frame + stop codons cttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13258 JY8QFUQ01BNB5K productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARRLNNYDSGEYAMDVW in-frame + tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13259 JY8QFUQ01CC01V productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 930 91.03 203/223 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [1.17.38.11] CTTAPSETYATEYFAMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13260 JY8QFUQ01CSCCB productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13261 JY8QFUQ01CYKSC productive Homsap IGHV3-74*03 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13262 JY8QFUQ01COKNO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13263 JY8QFUQ01B8KX2 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 823 87.04 188/216 nt 86.11 186/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); gtctctggggactccattagtggttactattggacgtggatccggcagAgccccagggaagggactggagtggattggaaatgtccattacactgggagtaCccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13264 JY8QFUQ01CH4A6 No results +13265 JY8QFUQ01DNGQ9 No results +13266 JY8QFUQ01B3J3Q No results +13267 JY8QFUQ01AW8ZH unproductive Homsap IGHV3-30*04 F, or Homsap IGHV3-30*10 F or Homsap IGHV3-30*17 F or Homsap IGHV3-30-3*03 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [1.17.38.11] CARDLASFCGGDCPIDY## out-of-frame + in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); cctctggatTtccccttcagcaattacgctatgcactgggtccgccaggctccgggcaaggggctggagtgggtggcacttatttcgtatgatgggactaataaatactacatagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacagtgtatctgcaaatgaatagcctgagacgtgaggacacggctgtgtatttctgtgcgagagatctggcatcattttgtggtggtgactgccccattgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +13268 JY8QFUQ01DCAKQ productive Homsap IGHV3-9*01 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame - tctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13269 JY8QFUQ01BCEIV productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13270 JY8QFUQ01ADCOG unproductive Homsap IGHV3-30*01 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGVTKARYGLDV## out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggGggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctgggggccaagggaccacggtcatcgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaac +13271 JY8QFUQ01CNT10 No results +13272 JY8QFUQ01C2CN9 No results +13273 JY8QFUQ01B4PG0 productive Homsap IGHV3-11*06 F, or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F 389 90.53 86/95 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 X X 11 X.X.11 [X.X.31.11] CARSGSGSHLDYW in-frame - tctctggattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13274 JY8QFUQ01CAV9Y productive (see comment) Homsap IGHV3-72*01 F 1073 98.64 218/221 nt 98.19 217/221 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-15*01 F 1 8 10 8 8.10.8 [1.16.38.11] CLRPPRYDPW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) tctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13275 JY8QFUQ01CNGY0 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 709 81.69 174/213 nt 81.22 173/213 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.37.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 130 in the user submitted sequence), (cause frameshift) ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacacgcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13276 JY8QFUQ01DIC8Q No results +13277 JY8QFUQ01CLO2L productive Homsap IGHV1-8*01 F 912 92.06 197/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [0.17.38.11] CAREGLLGSLGSW in-frame - aggatacaccttcatcagttatgatatcaattgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaacagcggtaacacagggtttgcacagaggttccagggcagagtaaccatgaccaggaacatctccataaacacggcctacatggagctgaccaacctgacatctgatgacacggccgtatattattgtgcgagagaaggtctattgggcagcctaggatcttggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13278 JY8QFUQ01A8ZQP unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*13 F 909 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGFLFFGELRRLRNGRL# out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtcactatggtatacactgggtccgccaggctccaggcaaGggggctagattgggtggcatttatatcatatgatggaagtaatGaggttttacgcagactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatggatttctattcttcggggaattacggaggcttcggaatggacgtctgggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13279 JY8QFUQ01AVC1T unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F (see comment) 368 64.39 132/205 nt 63.9 131/205 nt 8 7 X 8.7.X [1.17.34.X] null - No rearrangement found Low V-REGION identity (64,39% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13280 JY8QFUQ01CR5H7 unknown (see comment) Homsap IGHV3-23*05 F 99 52.59 71/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggatacagttttaacagttatgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13281 JY8QFUQ01B94JE unproductive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-3*01 F 1 8 10 X 8.10.X [1.17.38.11] CITSFGGRSLAY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13282 JY8QFUQ01AOYC9 unproductive Homsap IGHV4-61*01 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD1-26*01 F 3 10 7 X 10.7.X [1.17.38.11] CARGGLRWGLLEFDPG#W out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 67 of V-REGION: 'TATAATCCCCTG' (12 nucleotides at position 111 to 122 in the user submitted sequence), (do not cause frameshift); tctctggtggctccgtcagcagagatatttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatgtatcacagagggaacactaagTATAATCCCCTGtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtgggctccggtggggcctactggaatttgatccgggactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +13283 JY8QFUQ01AJRBP No results +13284 JY8QFUQ01CVFLT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13285 JY8QFUQ01BVCWL productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.37.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 194 in the user submitted sequence), (cause frameshift) ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggcccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13286 JY8QFUQ01C76FG productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13287 JY8QFUQ01B5LCE productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARLRDYEYSYGHPRAFDYW in-frame + ctctggattcacctttaataactactggatgagttgggtccgccaggctccagggaaggggctggactacatggccaatataaaggcagatggaagtgcgaagaattatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatttgcaactgaacagcctgagagtcgaggacacggctgtatatttctgtgcgagattgagggattatgaatacagctatggtcacccaagggcctttgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13288 JY8QFUQ01CY2HZ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1035 97.7 212/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame + gtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13289 JY8QFUQ01CBNOH productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13290 JY8QFUQ01CNKWE unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CARLTPLTMVPGNSLL#YHSMDVW out-of-frame + in FR3-IMGT at codon 74 of V-REGION: 'CACAACCCCTCCCTCCTG' (18 nucleotides at position 123 to 140 in the user submitted sequence), (do not cause frameshift); tctctggtggctccatgactggttactactggagttggatccggcggcccccaggtaagggactggagtggattggctatatctactacaccgggtacaacaactacaacccctccctcatcCACAACCCCTCCCTCCTGagtcgactcaccatatcagtcgacacgtccaagaaccagttctctctgacgctgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagattgacacccctgactatggttccggggaactcactactattaccacagtatggacgtctggggccaagggaccgcggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13291 JY8QFUQ01COFUU productive Homsap IGHV3-7*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame + cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcgggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13292 JY8QFUQ01CIBI1 No results +13293 JY8QFUQ01AZAQN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +13294 JY8QFUQ01BV7SZ unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 977 96.65 202/209 nt Homsap IGHJ5*01 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 3 6 8 X 6.8.X [X.17.38.11] CARQIDYGDFSRHGLDV## out-of-frame + acaactttaccggctactggatcggctgggtgcgccagcggcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgataccagatacagcccatccttccaaggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccgtgtattactgtgcgagacaaatagactacggtgacttctctaggcacggtttggacgtctggggcccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13295 JY8QFUQ01DRW1N No results +13296 JY8QFUQ01DW5HG unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 837 87.56 190/217 nt 87.1 189/217 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGEWEMLDH## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 212 to 212 in the user submitted sequence), (cause frameshift); ctccggattcaccttcagtaggtattggatgtattgggtccgccaagctccaggcaaggggctggtgtgggtctcacgcattaaaagtgatgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacatatTttttgtgcaagagacggggagtgggagatgcttgaccactgggggccagggagccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca +13297 JY8QFUQ01A7WQR unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 878 89.45 195/218 nt 88.07 192/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [2.17.38.11] CAREPPETIVVVVTVL#GAFDIW out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 140 to 140 in the user submitted sequence), (cause frameshift); ctgtctctggtggctcCcatgaggaattattacCtggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccCttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagaaccccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13298 JY8QFUQ01C5DFE productive Homsap IGHV3-11*01 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - gcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13299 JY8QFUQ01CBFFI productive Homsap IGHV2-5*02 F 1170 97.95 239/244 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 2 10 7 11 10.7.11 [9.17.38.11] CAHRRIRFGFDYW in-frame + gaccctcacgctgacctgcaccttctctgggttctcactcagcactggtggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcactcatttattgggatgatgataagcgctacagcccatctctgaagagcagactcaccatcaccaaggacacgtccaagaaccaggtggtcctcacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacaggaggatacgattcggctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13300 JY8QFUQ01BFE2F productive (see comment) Homsap IGHV3-30*01 F 874 89.04 195/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARDSVPRASEAAYHFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 213 to 213 in the user submitted sequence), (cause frameshift); gcctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttaCtttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13301 JY8QFUQ01DBM06 productive Homsap IGHV3-30*01 F 878 89.45 195/218 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [1.17.38.11] CACGHMRDGYDVW in-frame - cctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +13302 JY8QFUQ01A4F8J unproductive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARERGNSYGEIDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggcccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13303 JY8QFUQ01B05FW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +13304 JY8QFUQ01CQHZF No results +13305 JY8QFUQ01AMSW8 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found ctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13306 JY8QFUQ01BPEAY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13307 JY8QFUQ01A239T productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 807 85.45 188/220 nt 84.55 186/220 nt Homsap IGHJ6*02 F 187 79.66 47/59 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [2.17.38.11] CARRDSDFRMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 180 to 180 in the user submitted sequence), (cause frameshift); ggtgtctggatatgactttagcagattttGggatcgcctgggtgcgccagatgcccgggaaaaggctggagtggattggaatcatctatcctagtgactctgatacgagatacagtcccaccttccaaggccaggtcattatctcagccgacaagtccctcagtaccgcctacctacttTtttagcagtctgagggcctcggacaccgccatgtatttttgtgcgagacgtgattccgacttccgtatggacgtctggggccaggggaccacggtcaccgtgtctccaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +13308 JY8QFUQ01BNPKU productive (see comment) Homsap IGHV3-9*01 F 891 90.32 196/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDRGSSSKYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift);in CDR3-IMGT at codon 105 of V-REGION: 'T' (1 nucleotides at position 220 to 220 in the user submitted sequence), (cause frameshift); ctctggattcaactttggtgattacgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttGggggaagtgctcatatacactatgcggactctgtgaaggaccggttcaccatctccagagacaacgccatgaactccctttatttgcaaatggacagtctgagagctgacgactcggccttgtattactgtgTcaaaagatcggggtagcagttccaagtattactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13309 JY8QFUQ01APGJK unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13310 JY8QFUQ01AIUAX productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13311 JY8QFUQ01BY77H productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13312 JY8QFUQ01ASBW4 productive Homsap IGHV3-9*01 F 882 89.86 195/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + ctctggattcacctttgatgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtattagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcatcacatccagagacaatgccaagaactccatctatttgcaaatgaacagtctgagagatgacgacacggccttctacttctgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +13313 JY8QFUQ01DKFWU productive (see comment) Homsap IGHV3-33*05 F (see comment) 757 83.11 182/219 nt 82.65 181/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.17.38.11] CVKGRGYNDYGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); gcgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatAttaatgaaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13314 JY8QFUQ01DE4DF productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CARDVYNSRTNYFDLW in-frame + gtctggatttagcttcactaatcatggcatgcactgggtccgccaggctccaggcaaggggctggaatgggtggcacttattgtcgacgatggaagtaatggatattatgcagaccccgtgaggggccggttcaccatctccagagacaatcccaaaaacacactttatctgcaaatggacagcctgagagccgaggacacggctgtctactattgtgcgagagatgtctacaattcccgaactaattactttgacctatggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13315 JY8QFUQ01BM631 productive Homsap IGHV3-11*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKDRGKSGSYGLDHW in-frame + cctctgggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccagggtcaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgaaagatcgggggaaaagtgggagctacggacttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttccgctgagcctcgacagcaccccccaagcatgggaacgtggtccgtcgcatgcctggtccagggcttcttccccca +13316 JY8QFUQ01CM33P productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 979 93.69 208/222 nt 93.24 207/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [2.17.38.11] CARHGSGWLQELDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcatcagagacagtgcctactggggctggatccgccagcccccagggaaggGggctggagtggcttgggagcatctattatagtgggagtacctactacaatccctccctcaagagtcgagtcaccatatccgtagacacgtccaagaagcagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagacatggcagtggctggctccaggaacttgactactggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13317 JY8QFUQ01DFMQ1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 984 95.79 205/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD1-26*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARWRSRSYDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcaactatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattacaagtggtggtagcacatactacgcaaactccgtgaagggccggttcaccgtctccagagacagttccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagatggcgtagtcggagctacgactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13318 JY8QFUQ01ASBGR productive Homsap IGHV3-9*01 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame - cctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13319 JY8QFUQ01AR4XZ productive (see comment) Homsap IGHV3-48*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTRQTGNYYYFGVDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); cctctggatTtcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13320 JY8QFUQ01B9ETA unproductive (see comment) Homsap IGHV4-61*02 F (see comment) 473 68.35 149/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.37.X] null + stop codons no junction found Low V-REGION identity (68,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtgggggtgtcgactacaacccctccctcaggggtcgagtcaccatttcagcggacacgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13321 JY8QFUQ01A6CLA No results +13322 JY8QFUQ01A30KO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13323 JY8QFUQ01A1SIW productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARDRRGYSYEMDYW in-frame - ctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13324 JY8QFUQ01CDMFR productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1000 95.43 209/219 nt 94.52 207/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [2.16.38.11] CARDTLEVVSNMDDAFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) agcctctggattcaccttcagtcgttatagcatgaactggGgtccgccaggctccagggaagggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13325 JY8QFUQ01DF7T4 No results +13326 JY8QFUQ01BDGYS unproductive Homsap IGHV3-11*01 F 862 89.67 191/213 nt 88.73 189/213 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD2-2*01 F 3 8 7 X 8.7.X [1.16.38.11] CARDPYCSSTNCYPY## out-of-frame - in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaagggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactgggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13327 JY8QFUQ01CU5JV productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 947 92.31 204/221 nt 91.86 203/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [0.17.38.11] CTHLREEMSYEW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); ctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaAaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13328 JY8QFUQ01AJY27 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.37.11] CVRSEYSSSNWFDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) ctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcgggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13329 JY8QFUQ01CHKDD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKKYHYGSGTYYYHFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); gcctctggattcaccGtttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcgcaactattatttatagtggcgatagtacatactacgcagattccgtgaggggccggttcaccatctccagagacaattccaagaacactctgcatctgcatatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaaagtatcactatggttcggggacttattattaccacttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13330 JY8QFUQ01A20T6 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 889 91.08 194/213 nt 90.61 193/213 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 8 6 9 8.6.9 [1.17.38.11] CAKEEVPNDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) ttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgtttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgaaagaggaggtcccgaatgattattggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +13331 JY8QFUQ01ANT8E productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATSRGSANWYPFDHW in-frame + cctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13332 JY8QFUQ01A17TV productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.02 196/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'T' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagTttgggtccgccaggctccagggaagggactggagtCgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13333 JY8QFUQ01CPYJ0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttccccgctgagccctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13334 JY8QFUQ01DA34V productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactcaggcgccctgaccagcg +13335 JY8QFUQ01AZRBH No results +13336 JY8QFUQ01AMCLQ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13337 JY8QFUQ01BRY5N No results +13338 JY8QFUQ01BRRF8 productive (see comment) Homsap IGHV4-61*02 F 834 86.43 191/221 nt 85.52 189/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); tctccggtggctccatcagtacCtggttattactactGggagctggatccggcagtccnccggggaagggactgaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13339 JY8QFUQ01BF3SF unproductive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 285 82.35 70/85 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-13*01 F 3 X X X X.X.X [X.X.28.11] CVKDRKGSNWYYFEN# out-of-frame + Low V-REGION identity (82,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactgggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13340 JY8QFUQ01BJRW3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-3*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEAVSNMDDAFDIW in-frame + ctctggattcagcttcagtggttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtcgcatacattagtaggaggagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgggaggcgaggacacggctgtgtatttctgtgcgagagacaccctagaggcagtgtctaatatggatgatgcttttgatatctggggccaagggacaatggtcaccgtctctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13341 JY8QFUQ01C5XHC unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSDFYSTGH# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13342 JY8QFUQ01AYAME productive Homsap IGHV4-4*07 F, or Homsap IGHV4-61*02 F 944 93.49 201/215 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 7 19 8.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctccatcagtagtttctactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccaggccagatgggaacgtggtcatcgcctgcctggtcccaggggcttcttccccca +13343 JY8QFUQ01AUIPX No results +13344 JY8QFUQ01C44NL productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 925 92.96 198/213 nt 92.02 196/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.37.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'AC' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 173 in the user submitted sequence), (cause frameshift) ctctggattcaccgtcaataggaaACtgacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13345 JY8QFUQ01AS6HF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 743 82.57 180/218 nt 81.19 177/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [1.17.38.11] CTKTRVVLGITFPFYIYGLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'T' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 86 of V-REGION: 'G' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); cctctggattcacgttcgacaactatgccatgagctgggtccgccaggcaccaggaaaaGgggctggagtgggtctccagtatTtagtggtaatggagaaattgtacaccacgcagacgccgtgaagggccggttcaccatctccagagacaactccaagaacacGctgttttttgcaaatgaatggagtgagagacgacgacacggccatttactactgtacgaaaacacgcgttgtgttgggaattacatttccgttctatatctatggtctggacgtctggggccaagggaccacggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13346 JY8QFUQ01DK32V productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13347 JY8QFUQ01CFEJB unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt 90.32 196/217 nt 8 8 X 8.8.X [1.17.37.X] null + No rearrangement found in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 123 in the user submitted sequence), (cause frameshift) cctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcgggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgaccctggggccaggggaccctggtaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +13348 JY8QFUQ01C08YX productive (see comment) Homsap IGHV4-59*03 F 786 85.51 183/214 nt 85.05 182/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.37.11] CARGRTVVTVVDYVDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 109 in the user submitted sequence), (cause frameshift) tctctggtgactccattagtggttactattggacgtggatccgacagcgcccagggatgagcctggagtggattggacaagtccattacactgggagcaccaagtacagccctccctcaagagtcgagtcaccatttctgttgacatgtccaagaaccaattcaccctcatcttgacctctgtggccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttgttgactacgttgacttttggggtcagggagtcctggtcaacgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13349 JY8QFUQ01C0V8V productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 928 91.78 201/219 nt 91.32 200/219 nt Homsap IGHJ6*02 F 175 75.81 47/62 nt Homsap IGHD3-16*01 F 1 8 8 14 8.8.14 [2.16.38.11] CARAVGQRGYDGTDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) agcctctggattcatgttcagcagttattggatgagctgggtccgccaggatccagggaagggctggagtgggtggccaatataaacgaagaaggaagtgagaaatattatgtggactctgggaagggccgattcaggatctccagagacaacgccaagaattccgtgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgcgagagcagtggggcagcgaggctacgacggtacagacctctggggccaagggaccacggtcatcgtctccacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13350 JY8QFUQ01CYZEY unproductive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-8*02 F 1 8 8 X 8.8.X [0.17.38.11] CARDGYLPGNG#DFW out-of-frame + tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacgggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13351 JY8QFUQ01BFYY9 productive Homsap IGHV3-48*02 F 865 88.58 194/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD6-6*01 F 1 8 8 20 8.8.20 [2.17.38.11] CARDDSRLWSSSFNHYFAMDVW in-frame - ggctctggattcacctttagtgattatagaatgaattgggtccgccaggctccagggatggggctggaatgggttgcacacattagtaccagtggtagtagtatatactatgcagactctgtgaagggccgattcaccgtctccagagacgatgccaagaattcactttttctgcaaatggacagcctgagagacgacgacacggctgtatattactgtgcgagagacgattcacggctgtggagctcgtcatttaaccactatttcgctatggacgtctggggccaagggaccaccgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13352 JY8QFUQ01B0OA1 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 923 91.74 200/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKAGRGLIRPNNWFDPW in-frame + cctctggatttaccttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcggggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13353 JY8QFUQ01AYS47 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13354 JY8QFUQ01B6NYK productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13355 JY8QFUQ01BSIRY productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 815 86.24 188/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame + cctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13356 JY8QFUQ01B0FUB productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctggggcacagcggcccttgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13357 JY8QFUQ01A2SLU unproductive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1029 95.96 214/223 nt 95.07 212/223 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD5-24*01 ORF 1 10 9 X 10.9.X [0.17.37.11] CASEQR*PPR#FDYW out-of-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 92 of V-REGION: 1 nucleotides (from position 188 in the user submitted sequence), (cause frameshift) tccgggacagtgtctctagcaacagtgctgcttggaactggatcaggcagtCccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtgatataatgattatgcaatatctatgaagagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcaactgaatctgtgactcccgaggacacggctgtgtcttattgtgcaagtgagcagagatgaccacctagaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggctcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13358 JY8QFUQ01BL0VW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13359 JY8QFUQ01A8YWU productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 7 17 8.7.17 [2.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 97 in the user submitted sequence), (do not cause frameshift) gcgtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtggtcataatgcagcctacgcagatttcgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13360 JY8QFUQ01A9SRR unproductive Homsap IGHV4-61*02 F (see comment) 879 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 X 10.7.X [1.17.38.11] LXRDKGIVVDPG#DYW out-of-frame + Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtattttttggngcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13361 JY8QFUQ01DV1Q5 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKNNNDFGDYDWFDPW in-frame + tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactgggggcaccgactccaacccctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +13362 JY8QFUQ01CEJL7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame - ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13363 JY8QFUQ01BUU3D unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 922 92.13 199/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKLADTGEWSNRIFI#W out-of-frame - tctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatctttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13364 JY8QFUQ01DAGOQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13365 JY8QFUQ01AX6NH productive (see comment) Homsap IGHV3-9*02 F (see comment) 665 79.07 170/215 nt 78.14 168/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 7 7 15 7.7.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,07% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 59 of V-REGION: 2 nucleotides (from position 90 in the user submitted sequence), (cause frameshift) cctctggattcaacccgaaaactttgccatgcactgggtccgacaagttccagggaagggcctgaagtgggtctcaggtataattggaatggacgaaaacaggatatgcggagtctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13366 JY8QFUQ01BCW6H productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13367 JY8QFUQ01BP55P productive (see comment) Homsap IGHV3-7*01 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 8 14 7.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) ctctggatttacttttacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13368 JY8QFUQ01BOHMT No results +13369 JY8QFUQ01DAUMA unproductive Homsap IGHV3-7*01 F 963 94.01 204/217 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CASDLGGQKSY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +13370 JY8QFUQ01DF8OD productive (see comment) Homsap IGHV3-48*01 F 1080 100.0 217/217 nt 99.08 215/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 76 of V-REGION: 'G' (1 nucleotides at position 131 to 131 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgaGttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgatgtcgtggaactcag +13371 JY8QFUQ01BVD6B productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 732 82.71 177/214 nt 82.24 176/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.16.38.11] CARDWGGSFDRYYFDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 72 in the user submitted sequence), (cause frameshift) tccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13372 JY8QFUQ01B1I2X No results +13373 JY8QFUQ01CZDE0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 815 86.24 188/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD2-21*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDPQQILAEVNWFDPW in-frame + cctctggattcacctttcgcagctacgccatgagttgggtccgccaggctccaggaagggggctggagtgggtctcctcaatcagtggcagtggtgataaaacaaaatatgcagactccgtgaagggccgattcaccatctccagagacaatgcgaggaacactttttatctgcatatgaacagcctcagagccgcggacacgggcgtctactattgtgcgaaagatcctcagcagatactggcagaagtaaactggttcgacccctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13374 JY8QFUQ01DGXWV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.09 202/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGHLLD#DYW out-of-frame - in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccaactatggcatgagctgGggtccgccaggctccagggaaggGggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtngaggacacggccgtttattactgtgcgagattcggccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13375 JY8QFUQ01A8G7W No results +13376 JY8QFUQ01B2Y30 unknown (see comment) Homsap IGHV1-2*01 F, or Homsap IGHV1-2*02 F or Homsap IGHV1-2*04 F or Homsap IGHV1-2*05 F 142 82.93 34/41 nt 8 X X 8.X.X [0.5.X.X] null + No rearrangement found tggatacacattcaccggccacttcgtccactggctgcgac +13377 JY8QFUQ01CD2NF productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 875 90.57 192/212 nt 90.09 191/212 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 6 15 8.6.15 [1.17.38.11] CAKNNNDFGDYDWFDPW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattctgggggcaccgactccaacccctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +13378 JY8QFUQ01DSGPB productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 921 90.58 202/223 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD2-21*01 F 2 8 10 8 8.10.8 [1.17.38.11] CTSNSWLDRW in-frame + ctctggattctctttcagtaatgcctggatgaattgggtccgccaggctccagggaaggggctggaatgggttggccatattaaaagggaaattgatggtgggataacaaactacgctgcacccgtgaagggcagattctccatcgcaagagatgattcaaagaatatgatgtatttgcaaatgaacagcctgaacaccgaggacacaggcgtgtattactgtacctcaaattcgtggctcgaccgctggggccagggaacccccgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc +13379 JY8QFUQ01B4PTS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 886 90.28 195/216 nt 88.43 191/216 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKNRGSAMADWYFDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'ACT' (3 nucleotides at position 82 to 84 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'C' (1 nucleotides at position 145 to 145 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'G' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); tctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattACTaatggtggtggtggtgtcgtactctacgcagactccgtgaagGggccgattcaccatctcCcagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttaGtttctgtgcgaaaaatagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13380 JY8QFUQ01BI30M No results +13381 JY8QFUQ01B0L5R productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.16.38.11] CARGLAVILGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccaggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13382 JY8QFUQ01DJ2CJ No results +13383 JY8QFUQ01BMUVB No results +13384 JY8QFUQ01DTIOK No results +13385 JY8QFUQ01BOGQI productive Homsap IGHV3-7*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame + cctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13386 JY8QFUQ01CK7Z9 productive Homsap IGHV3-11*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARLASSSGWYFDYW in-frame + ctctgaattcctcttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtgggtttcatacattagtaatagtggtggtaccatatactatgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaagacacggccgtgtattactgtgcgagattagcaagtagcagtggctggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +13387 JY8QFUQ01C4L2P No results +13388 JY8QFUQ01ALBC2 No results +13389 JY8QFUQ01DGY0R productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 817 85.59 190/222 nt 84.23 187/222 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARRHYGEGLFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); tcctttggtggctccatcagcCaataataattacttcctgggctggatccgccaGgcccccagggaaggggctggagtggattCggggatgtccagtatagtgggagcacctactccagcccgtccctcaagaggcgggtcaccatgtctgtggacgtgtccaaaagtcaggtctccctgagactgagctctgtgaccgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcctgcctggtccagggcttcttccccca +13390 JY8QFUQ01C58JQ productive Homsap IGHV3-33*05 F (see comment) 757 83.11 182/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.17.38.11] CVKGRGYNDYGLDYW in-frame - Low V-REGION identity (83,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13391 JY8QFUQ01ASO1O productive Homsap IGHV3-66*02 F 926 92.56 199/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 7 17 8.7.17 [1.17.38.11] CSTPTYCRGGSCSQIFDYW in-frame + cctctggattcaccgtcagtaactaccacatgaggtgggtccgccaggctccagggaaggggctggagtgggtctcagttatttacagcggtggtagtacatattacatagactccgtgaagggccgattcaccatctcgagagacgattccgagaacacagtgtatcttcaaatgaagagcctgagagctgaggacacggctgtatattactgttcgacgcccacatattgtaggggcggtagctgttcccagatttttgactattggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +13392 JY8QFUQ01A5MH8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 980 95.35 205/215 nt 94.88 204/215 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.16.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) tctggattcacctacagcagctatgccatgagctggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13393 JY8QFUQ01B8KSE productive Homsap IGHV3-30*10 F (see comment) 734 82.11 179/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame + Low V-REGION identity (82,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +13394 JY8QFUQ01AGZXJ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13395 JY8QFUQ01CPHOZ productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13396 JY8QFUQ01DI527 unknown (see comment) Homsap IGHV1-2*02 F 551 91.54 119/130 nt 8 8 X 8.8.X [X.17.10.X] null + No rearrangement found ggatacaccttcaccggcacctatatacactgggtgcgacaggcccctggacaagggcttgagtgggtgggattaatcaaccctagcagtggtggcacagagtctgcacagaagcttcagggcagggtca +13397 JY8QFUQ01CL2UN productive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13398 JY8QFUQ01BAQO7 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGV*QWL##DFDCW out-of-frame + stop codons cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13399 JY8QFUQ01B1Z10 No results +13400 JY8QFUQ01DS4FP productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13401 JY8QFUQ01CM7R2 No results +13402 JY8QFUQ01CWYLL productive Homsap IGHV4-61*02 F 960 93.18 205/220 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + ctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13403 JY8QFUQ01BUVHG productive (see comment) Homsap IGHV3-7*01 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); agcctctggattcacatttagtGaattattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13404 JY8QFUQ01DR2MY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD4-11*01 ORF 3 8 8 12 8.8.12 [1.17.38.11] CARHLTPEDAFDIW in-frame + ctctggattcacctttgacaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtgttagtggtcctggtggtaacacataccacgcagactccgtgaagggccggttcaccgtctccagagacaattccaagaacatgctgtttctgcaaatgaacagtctgagggtcgaggacacggccgtttattactgtgcgagacacctgactccagaggatgcttttgatatttggggccaagggacaatggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13405 JY8QFUQ01BVAV2 unproductive (see comment) Homsap IGHV3-66*02 F 858 89.25 191/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-16*01 F 2 8 7 X 8.7.X [1.17.38.11] CARQTAPFGVL*GL# out-of-frame + stop codons ctcggaattctccgtcagtgacagtcacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtagtgcatattatgcagactccgtgaggggccgattcaccatcgccagagacaaatctaagaacgtgttgtatcttcaaatgaacagtctgagacctgaggacacggctgtgtactactgtgcgagacagactgccccttttggggtactttgaggactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +13406 JY8QFUQ01CEFA0 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggGggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13407 JY8QFUQ01CBDGL unproductive Homsap IGHV3-11*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcaccttcagtgaccactacatgagttggatccgccaggctccagggaaggggctggagtggatttcatatattagtactagtggtaatatgatttattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaactcactgtatctgcagatgaacagcctgagagccgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13408 JY8QFUQ01AFBW7 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 906 90.0 198/220 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found agcctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13409 JY8QFUQ01DVAOU productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 908 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [2.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); gcttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaTggggctggantgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13410 JY8QFUQ01DO65C No results +13411 JY8QFUQ01BDP3S productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13412 JY8QFUQ01COSJG productive Homsap IGHV3-9*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13413 JY8QFUQ01AJVUU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 270 92.19 59/64 nt Homsap IGHJ4*02 F 199 89.58 43/48 nt Homsap IGHD3-22*01 F 3 X X 19 X.X.19 [X.X.21.11] CAKDVSTRITMRVVVPXLDYW in-frame - taagaacatcctgtatctgcacatgaacagcctgagagccgaggactcggccgtatattactgtgcgaaggatgtttccacgcgtattactatgagagttgtggtgccancccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +13414 JY8QFUQ01CG89R productive (see comment) Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 749 82.27 181/220 nt 81.82 180/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARVWVAGSRDENFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); tctcgggtggttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctAggagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgacctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13415 JY8QFUQ01CHPQV No results +13416 JY8QFUQ01AOYZF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 977 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtcagtactggatgtactgggtccgccaagntccagggaaggGggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13417 JY8QFUQ01CHHBI productive Homsap IGHV3-11*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggcagtgctactaccatatcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaaaaactcactttatctgcaaatggacagcctgagagccgaggacacggccatatattactgtgtgaggcgggtgtggggatacagttatggttccgtttcgtactactttgaatactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13418 JY8QFUQ01BNH8C productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 922 91.71 199/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacnccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13419 JY8QFUQ01B0MOL unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKPPPVDIVVTT#EFW out-of-frame - in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); tctctggattcacctttaacaactatgccctgagttggttccgccaggctccagggaggggactggagtgggtctcagccgttagtggtagtggtgattatacatattacgcagactccgtgAaagggccggttcaccatttccagagacaattccaagaacacactgtggctgcaaatgaacagactgagagccgaagacacggccgtatattactgtgcgaagcctccccccgtggatatagtggtgacgacattgagttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13420 JY8QFUQ01B0MKR No results +13421 JY8QFUQ01BJ8BC productive (see comment) Homsap IGHV3-11*01 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ6*02 F 263 94.83 55/58 nt Homsap IGHD1-26*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDYYYYGMDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'GGG' (3 nucleotides at position 95 to 97 in the user submitted sequence), (do not cause frameshift); ttctgggttctccttcagcgactacttcatgagttgggtccgccaggctccagggaagggactggagtgggttgcatacattagtagtagtggtGGGactactaaatactacgcagactctgtgaagggccgattcaccatctccagggacaacggcaagaattcattgtttctgcaaatggacagcctgagagtcgacgacacggccatgtatttctgtgtgagagactactattattacgggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +13422 JY8QFUQ01CB01H productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccgag +13423 JY8QFUQ01BV9NQ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 902 90.05 199/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 18 to 19 in the user submitted sequence), (cause frameshift); aggcctctggattcaccCTttgggttattatggcatggactgggtccgccaagctccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13424 JY8QFUQ01CGG9A productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13425 JY8QFUQ01B7JOI productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); gtttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +13426 JY8QFUQ01AEO6U productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARELGGSGTCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); tggatacaccttcaccaggcactatatgcactgggtgcgacaggcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggGggcagagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13427 JY8QFUQ01DODF2 unproductive Homsap IGHV3-48*01 F 1085 99.54 217/218 nt 99.08 216/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 1 8 8 X 8.8.X [1.17.38.11] CASIFGVVPPG##YYYGMDVW out-of-frame + in FR3-IMGT at codon 94 of V-REGION: 'C' (1 nucleotides at position 186 to 186 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcCctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttccccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaggagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttgccccgaaccggtgacggtgtcgtggaaactca +13428 JY8QFUQ01CSCY0 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactGgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatcccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13429 JY8QFUQ01BLSTS No results +13430 JY8QFUQ01C5A15 productive Homsap IGHV1-3*01 F 822 87.38 187/214 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [0.17.38.11] CVRGRSPPGDWFDPW in-frame + tggatacaccttcactaattatgctctgcaatgggtgcgccgggcccccggacaaacttttgagtggctgggatggatcaactctgccaatggcaacacaaaatattctcagaagtttcagggcagagtcgccattaccagggacacatccgcgaggacaacttacatggaattgagcagtctgacatctgaagacacggcgacatattattgtgtgagaggaagaagtccgcccggcgactggttcgacccctggggccagggaaccctgtcaccgtctccgtcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13431 JY8QFUQ01CKL3B No results +13432 JY8QFUQ01BM80W productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 912 91.59 196/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [0.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + tggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13433 JY8QFUQ01B80FV productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 959 93.58 204/218 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDAFEMW in-frame - cctctggattcatctttgatgattttggcatgaattgggtccgccaagctccagggaaggggctggagtgggtcgctggtatcagttggaatggtggcaaagcaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcaatgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13434 JY8QFUQ01CA99E unproductive (see comment) Homsap IGHV3-11*04 F (see comment) 450 67.28 146/217 nt Homsap IGHJ2*01 F 31 64.71 11/17 nt Homsap IGHD7-27*01 F 3 8 8 2 8.8.2 [1.17.38.5] NR*R in-frame + stop codons Low V-REGION identity (67,28% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcatggtatacctggcagactccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13435 JY8QFUQ01C8YCZ unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 110 100.0 22/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggattcaccttcagtga +13436 JY8QFUQ01A19DA unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 605 78.87 153/194 nt 78.35 152/194 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD3-22*01 F 2 8 1 X 8.1.X [1.16.38.11] ESVAPLLLMIR#PG out-of-frame + stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01A19DA ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (78,87% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 55 of V-REGION: 24 nucleotides (from position 78 in the user submitted sequence), (do not cause frameshift) cctctggactctccttcagtgggtaaaatatgaactgggtccgccaggctccaggggagggactggagtgggtctccaaatattacacagactcactgaggggccgattcaccatctccagagacagcgccaagaactcactccttctgcaaatgaacaggctgagagtcgaagtgtgcgaaaaaacgagagaaagtgtggcacccctgttactaatgattcgacccctggggccggggaaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctgacgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13437 JY8QFUQ01AV35P No results +13438 JY8QFUQ01CO4OD productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); gttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgGacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaatcccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13439 JY8QFUQ01DEZVI productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 678 79.91 171/214 nt 79.44 170/214 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) ctctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaagggactacttccccgaaccggctgacggtgtcgtggaactca +13440 JY8QFUQ01AUKEV No results +13441 JY8QFUQ01BV2F7 productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 929 91.4 202/221 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 10 7 18 10.7.18 [1.17.38.11] CARSAYCGADCYSADYLQHW in-frame + tctctggtggctccgtcagcagtaggggttactactggaactggatccgccagttcccagggaagggcctggagtggattgggaacatcttttacagtgggggcacctacgacaacccgtccctcaggagtcgaatttctatatcattagacacgtctaagaaccaattctccctgaagttgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcacgcacccagccagatgggaacgtgtcatcgcctgcctggtccagggcttcttccc +13442 JY8QFUQ01ANXF5 No results +13443 JY8QFUQ01C89O8 productive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13444 JY8QFUQ01AIVDQ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - tctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggccctcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13445 JY8QFUQ01ADNGT productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame - gtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13446 JY8QFUQ01AZDHR unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 819 97.66 167/171 nt 8 7 X 8.7.X [1.17.23.X] null + No rearrangement found cctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttc +13447 JY8QFUQ01CJOWG productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13448 JY8QFUQ01CCQXQ No results +13449 JY8QFUQ01AHXYO productive (see comment) Homsap IGHV3-7*01 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVRDLTADFYVSGSYRSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); ctctggattcaccttcaggagttattggatgaattgggtccgccaggctccagggaaGggggctggagtgggtggccaccataaAagcaagatggaagtgagaaatattatgtagactctgtgaagggccgattcaccatctccagagacaacgccaatgattcactgtatctgcaaatgaacagccttagaaccgaggacacggctgtgtattactgtgtgagagatttaacagcggatttctatgtttcggggagttatcggtcttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca +13450 JY8QFUQ01BDV4O productive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARCPNYNIGTRGFDYW in-frame + tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13451 JY8QFUQ01DJ0K8 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13452 JY8QFUQ01AJ3PL No results +13453 JY8QFUQ01BTMQU No results +13454 JY8QFUQ01CI2OQ unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDNYGDYW# out-of-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13455 JY8QFUQ01AEVWH productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame + ctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13456 JY8QFUQ01BE1BL productive Homsap IGHV3-13*01 F, or Homsap IGHV3-13*02 F (see comment) 746 83.26 179/215 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-10*02 F 2 8 7 18 8.7.18 [1.17.38.11] CARGRRDYYDRSAYPHLDSW in-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gctctggattcatcttcactaactccgacatgcactgggtccgccaaactccaggagggagtctggagtgggtctcaggcattggaactgctgctgacacattctatgcagactctgtgaggggccgcttcaccatctccagagacaatcccaaggactcgatgtaccttcagatgaacagcctgagagccgaagacacgggcatatatttttgtgcaagaggacgtagagattactatgataggagtgcttatccccacctcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13457 JY8QFUQ01ASSOO unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 X 8.7.X [1.17.38.11] CARGTPV*QRS#DAFDVW out-of-frame + stop codons Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggaccccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13458 JY8QFUQ01BJOCP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + tctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13459 JY8QFUQ01ATTL9 productive (see comment) Homsap IGHV3-30*01 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 1 7 8 16 7.8.16 [1.17.38.11] CAKDELPWDTIEYYFDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaatatttttctatgcactgggtccgccaggctccaggcaagggactagagtgggtgtcacttgtttcatatgatggatctaagaaaaagtacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatgagctgccttgggacacaattgaatattattttgactattggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgggtccagggcttcttccccc +13460 JY8QFUQ01A2YPP productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 915 90.91 200/220 nt 90.0 198/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [2.17.38.11] CATSRGSANWYPFDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 180 to 180 in the user submitted sequence), (cause frameshift); agcctctggattGcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaAatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13461 JY8QFUQ01ANQTV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDREDSSGYYFFRDGFDIW in-frame - ctctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctccggtattggtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagatcgtgaagatagtagtggttattacttcttccgtgatggttttgatatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcatgcctggtccagggcttcttccccca +13462 JY8QFUQ01A23UZ productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13463 JY8QFUQ01C0WA2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13464 JY8QFUQ01DJQF1 No results +13465 JY8QFUQ01BPYSL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13466 JY8QFUQ01AFO27 unproductive Homsap IGHV3-7*01 F 1022 96.79 211/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSGFYSTGY## out-of-frame - cctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13467 JY8QFUQ01BRI34 unproductive Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARPAGEGDPFS#YYSGLDVW out-of-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgaccctttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13468 JY8QFUQ01CEEMM productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 585 92.65 126/136 nt 91.91 125/136 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-18*01 F 1 8 X 15 8.X.15 [0.3.34.11] CAIVDTNLVSATGKDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 42 of V-REGION: 78 nucleotides (from position 35 in the user submitted sequence), (do not cause frameshift) tggatacaccttcagcaactactatagacactggaaatttcagggcagagtcaccatgaccagggacacgtccacgagcacagtcttcatggagctgagtagcctgagatctgacgacacggccgtgtattattgtgcaatagtggacacaaatttggtttcggcgaccggtaaagactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13469 JY8QFUQ01DDGWX productive (see comment) Homsap IGHV3-9*01 F 904 91.2 197/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'CG' (2 nucleotides at position 138 to 139 in the user submitted sequence), (cause frameshift); tctggattcaccGtttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaagGggccgattcaccCGtctcccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13470 JY8QFUQ01CCBKP No results +13471 JY8QFUQ01AGO9G productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13472 JY8QFUQ01DKWW9 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 934 91.44 203/222 nt 90.99 202/222 nt Homsap IGHJ6*01 F (see comment) 125 76.74 33/43 nt Homsap IGHD4-17*01 F 1 8 10 X 8.10.X [1.17.37.11] CTTESAY# out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 161 in the user submitted sequence), (cause frameshift) ctctgcattcactttcagtaatgcctggatgacctgggtccgccaggctccagggaaggggctggagtggcttggccgtattaaaaggaaagttgatggtgagacaacagactacgctgcatccgtgaagggcagattcaccatctggagagatgactcaaaaacactctatatctgcaaatgaacagcctggaacccgaggacacagccgtatattattgtaccactgaatctgcctattggggccagggaacctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgcctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13473 JY8QFUQ01BDHUE productive Homsap IGHV3-7*03 F 806 85.78 187/218 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13474 JY8QFUQ01CLKWA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13475 JY8QFUQ01BJQ6B productive Homsap IGHV1-2*02 F 790 85.51 183/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDWGGTYAPLDNW in-frame - tggatacattttcaccggctactatttacactgggngcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaaccttgaccagtgacacgtccatcagtacagcctacatggaaatgagcgggctgacgtctgaggacacggccatcttttactgtgcgagagattggggtggcacgtacgctccgcttgacaattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgcctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13476 JY8QFUQ01CEHBJ productive Homsap IGHV1-2*02 F 849 88.79 190/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*01 F 3 8 8 19 8.8.19 [0.17.38.11] CARDEANIEVVMTSNYYFDYW in-frame + tggatacaccttcaccggccactatctacactgggtgcgacaggcccctggacaaggacttgagtggatgggatgggtaaacatcaagagtggtgacacaaattatccacagaagtttcacggcaggatcaccatgaccagggacacgtccatcaacacagccttcttagaagtgaccagcctgagatctgacgacacggccgtttattactgtgcgagagacgaggccaatattgaagtagtaatgacctctaattattattttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +13477 JY8QFUQ01CG5NM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 890 90.7 195/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 8 17 8.8.17 [0.17.38.11] CAKDLVVTQYWPQGIHGHW in-frame - ctgggttcacctttagcagctatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaagtatcagttttagtggtgagagaacatattatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacagtacatttgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaagatctggtggtgactcagtattggccccagggaatccatggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13478 JY8QFUQ01CL755 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDEIPWDTIEYY#FDYW out-of-frame - ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacggtgtacctgcaaatggacagcctgaggcctgaagacacggctgtgtattactgtgccagagatgagatcccttgggatacaatagagtactaccttttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagacctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +13479 JY8QFUQ01CGW3W unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt 10 7 X 10.7.X [1.17.38.X] null - No rearrangement found tctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgaacccctgggggccagggaaaccctgggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +13480 JY8QFUQ01CMB6M productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +13481 JY8QFUQ01CUOC4 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactca +13482 JY8QFUQ01B95BW productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1060 100.0 213/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - tctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13483 JY8QFUQ01CZZ6E productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgGggagtggtnttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13484 JY8QFUQ01DTRRU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13485 JY8QFUQ01BFUON unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 912 92.06 197/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [0.17.38.11] CARLGATR##DYW out-of-frame + stop codons tggatacagctttaccaattactggatcggctgggtgcgccaggtgcccggaaaaggcctggagtggatggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttggggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13486 JY8QFUQ01AVQS1 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 799 86.38 184/213 nt 85.92 183/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.37.11] CATLRGGTFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 109 in the user submitted sequence), (cause frameshift) ctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaaccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13487 JY8QFUQ01AG5SF No results +13488 JY8QFUQ01CDJWO unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1070 97.77 219/224 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*02 F 3 8 10 X 8.10.X [1.17.38.11] CTTDGGPSRP#FDFW out-of-frame + stop codons cctctggattcaccttcagtaacgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaaactgctggtgggacaacagactacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcaaagaacacgctgtatttgcaaatgaacagcctgaaaaccgaggacacagccgtgtattattgtaccacagatggggggccatctcgtcccctttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13489 JY8QFUQ01C4CZ9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13490 JY8QFUQ01DBM8Q productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13491 JY8QFUQ01CYIO3 No results +13492 JY8QFUQ01ACVYI No results +13493 JY8QFUQ01COR4B productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 921 90.58 202/223 nt 90.13 201/223 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-15*01 F 2 8 10 18 8.10.18 [1.17.38.11] CATHGVGSSWAHYYFGLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); ctctggattcaccctcaaaaacgcctggacgagctgggtccgccagggtccagggaaggggctggagGtgggttggccgcattaagagcaaatctgaaggtggggcaatagactacgctgcacccgtgaagggcagatttaccatctcaagagatgattcagaagacacactgtttctgcaaatgaacagcctgagagccgaggacacagccgtgtattattgtgccacgcacggtgttggcagcagctgggcccactactacttcggtctggacgtctggggccaagggaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacaacacccccccaagtggtcgtcgcatgcctggtccagggcttcttccccca +13494 JY8QFUQ01A3ZP1 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 900 90.78 197/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) ggcctctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13495 JY8QFUQ01BO268 productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGHW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +13496 JY8QFUQ01CFT0C No results +13497 JY8QFUQ01DCWKM productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +13498 JY8QFUQ01CTU32 productive Homsap IGHV3-48*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13499 JY8QFUQ01CMTAN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13500 JY8QFUQ01B2JS1 productive (see comment) Homsap IGHV3-7*01 F 841 87.96 190/216 nt 87.5 189/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.37.11] CGRDERGADLPNDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 190 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagcccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctggggcctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13501 JY8QFUQ01AVA0Q productive Homsap IGHV2-5*02 F 1134 96.31 235/244 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 10 7 13 10.7.13 [9.17.38.11] CAHRGNYGDYVFDSW in-frame + gaccctcacgctgacctgcaccttctctggattctcacttagcactagtgggatgggtgtgggctggatccgtcagcccccaggaaaggccctggaatggcttacactcatttattgggatgatgataagcgctacagcccatctctgaagagcaggctcgccatcaccaaggacacctccaaaaatcaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattattgtgcacacagagggaattacggtgactatgtttttgactcctggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +13502 JY8QFUQ01BHUV1 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 764 84.19 181/215 nt 83.26 179/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 13 8.7.13 [1.17.38.11] CARRPPYGGNRFDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); tgtctggtgggtcctccaatggattttactgggactggatccgccagcccccagggaaggggctagaatggattggagaaatgaaccatgagggaagcagctcatacaccccgGtccctcagGgggtcgagtcaccatttcaggagacacgtccaagaaccagatctccttgaaaatcacctctgtgaccgccgcggacacggctgtatattattgtgcgagacgtcccccctatggtggtaatcgctttgactactggggccagggagtcctggtctccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +13503 JY8QFUQ01DQVYX productive Homsap IGHV3-48*02 F 891 90.32 196/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [1.17.38.11] CARGQKWLQVLRWFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13504 JY8QFUQ01AIH3K unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 121 69.81 37/53 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVVWSLWYFDL## out-of-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctgggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13505 JY8QFUQ01C61MV productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13506 JY8QFUQ01CB3VX unproductive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 976 94.91 205/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAGDLTGGSVLL*Q*WFK#YW out-of-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); tctagattcaGccttcagtagctataatatgcactgggtccgccaggctccaggcaaggggctagagtAgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactgggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13507 JY8QFUQ01DPW2S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-3*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDGVRGLGAYYIYYFDSW in-frame + cctctggattcacctttggcctctatgccatgaactgggtccgccagactccagggaaggggccggagtggctcgcaactatcagtggtagtggaagtaggtcattctacgcagactccctcaggggccgtttcaccatctccagagacaattccaagggcacggtgtacctggacatgaccaccctgggagccgacgactcggccgtgtattactgtgccagagatggagtccgtggccttggtgcttattatatctactattttgactcatggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13508 JY8QFUQ01ALJ17 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVKGWYHIPDYW in-frame + ctctggatttacctttggcagctatgccatgagctgggtccgccaggctccaggcgaggggctcaagtgggtctcaactattggtggtagtgatggtcgcacatactacacagcctccgtgaagggcctgttcacctcctccagagacaattccaagaacacggtgtatctgcatatgaacggcctgagagtcgacgacacggccgtctattactgtgtaaaaggctggtaccacatcccagactactggggccagggaatcttggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13509 JY8QFUQ01B61YI productive Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13510 JY8QFUQ01BM39D unknown (see comment) Homsap IGHV3-72*01 F 102 53.03 70/132 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons tctctggattcaccttcagtgaccactacatggactgggtccgccaggccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +13511 JY8QFUQ01BWJ7V productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 872 89.77 193/215 nt 88.37 190/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVSDLAGQKGSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'TG' (2 nucleotides at position 51 to 52 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'GC' (2 nucleotides at position 62 to 63 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); caggattcaccttcagtaggtactggatgcactgggtccgccaagttccaTGgggaaggggGCccggtgtgggtctcacgtattaatgaagacggcagccCacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13512 JY8QFUQ01A82ZK unproductive Homsap IGHV4-39*03 F 880 88.69 196/221 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-10*01 F 3 10 7 X 10.7.X [2.17.38.11] CTREGT#YYYGMDVW out-of-frame - gtctctggcggctccatcagcaatactgattattactgggtctggatccgccagccccacgggaagggactggagtggattgggagtatcgatttcagtgggagcaccaactacaacccgtccctcaagagtcgagtctccatatccatagacacgtccgagaaccgattctccctgaggttgaattctgtgaccgccgcagacacggccgtctattattgtacgagagaggggaccctactactacggtatggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13513 JY8QFUQ01C3410 unproductive (see comment) Homsap IGHV4-61*02 F (see comment) 874 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 X 10.7.X [1.17.38.11] LXETRG**WTLE#DYW out-of-frame + stop codons Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtattttttgngcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13514 JY8QFUQ01AYTNW productive (see comment) Homsap IGHV4-4*07 F 935 93.02 200/215 nt 91.63 197/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [2.16.38.11] CARGKDYYDSTGSLEDGLDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'AC' (2 nucleotides at position 14 to 15 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'A' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gtctctggtggctACccctcagtacttactactggaactgggtccggcagcccgccggaagggactggagtggattgggcgtaaatatcccagtggggacaccaactataatccctAccctcaaaagtcgagtcaccatgtcactagacacgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagagggaaggattactatgatagtactggttccctcgaggatggtcttgatatctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13515 JY8QFUQ01DT8QJ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13516 JY8QFUQ01CMSBH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDREDSSGYYFFRDGFDIW in-frame + ctctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctccggtattggtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagatcgtgaagatagtagtggttattacttcttccgtgatggttttgatatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13517 JY8QFUQ01DSCTQ productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13518 JY8QFUQ01DOLGG unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + in FR3-IMGT at codon 89 of V-REGION: 'A' (1 nucleotides at position 173 to 173 in the user submitted sequence), (cause frameshift); cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttAgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagactgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13519 JY8QFUQ01AHMZ7 unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F (see comment) 404 65.42 140/214 nt 10 9 X 10.9.X [1.17.33.X] null + No rearrangement found Low V-REGION identity (65,42% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccgggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13520 JY8QFUQ01BNVKG productive (see comment) Homsap IGHV4-34*03 F (see comment) 760 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [2.17.38.11] CTRGRLDAWEVSDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gtcgacgatgggtcctgtagagagtgcttctggagttggatccgccagtccccagggaagggtctggagtggattAggggacgtcaattatagacgaggcgtcgactacaacccgtccctcaagagtcgagtgaccatatcattggacacgtccaacaaacaagtctccctgagtctgagttctgtcaccgccgcggacacggccatgtattattgtacgcgagggcgattagacgcgtgggaagtatcggaccactggggccagggaaccgtggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13521 JY8QFUQ01B889O productive Homsap IGHV1-3*01 F 831 87.85 188/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagagcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13522 JY8QFUQ01CZ6OP productive Homsap IGHV3-64*02 F 953 93.95 202/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVTCGDYSYEYW in-frame - ctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13523 JY8QFUQ01DLRZ7 productive Homsap IGHV3-7*03 F 846 88.02 191/217 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcatttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggcaacgtggtcgtcgcatgcctggtccagggcttcttccccc +13524 JY8QFUQ01AXKCQ productive (see comment) Homsap IGHV3-11*01 F (see comment) 738 82.49 179/217 nt 82.03 178/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARGYSQKGVFDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) cctctggattcagtttcaaggaccactacatgagctggttccgccaggctccagggaagggactggagtgggttgcatacatcgatgccggtggggtactgactactacgcagactctgtggagggccgattcgtcgtcgccagggaaaatgacaagaatttattgcttctgcaaatgcacagcctgacagtcgaagacacggccgtatattactgtgcgagagggtacagtcaaaaaggggtttttgaccactggggccagggaatcctggtcaccgtttccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13525 JY8QFUQ01CLOBT productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.37.11] CARKRVPGGTFYGDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagatccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +13526 JY8QFUQ01DCUR6 unproductive (see comment) Homsap IGHV4-39*02 F 839 86.88 192/221 nt 86.43 191/221 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 X 10.7.X [1.17.38.11] CARHVVFGQ*IQCLASY##DSW out-of-frame + stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtgaccccatcggcaacactgcttactcctGggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggtttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatcccctgaccagccccaaggtcttgcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +13527 JY8QFUQ01B77EG unproductive (see comment) Homsap IGHV4-61*02 F 857 87.78 194/221 nt 87.33 193/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CAREGAWLHLQEV#FDYW out-of-frame + stop codons in CDR2-IMGT at codon 59 of V-REGION: 'ATT' (3 nucleotides at position 96 to 98 in the user submitted sequence), (do not cause frameshift); tctctgacgactccatcagcagtggcacttactactggagttggatccggcagcccgccgggaaggctccggagtggattggccgcttctatactATTactgggcgcaccaactacaatccctccctcgagagtcgagtcaccataacaagggacgtgtccaagaatcagttctccctgagactgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagagagggggcatggctacatctacaagaggtcttttgactactggggccagggaatcctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +13528 JY8QFUQ01ALWQH productive (see comment) Homsap IGHV3-64*02 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); cctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatgggggAtaacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtatcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca +13529 JY8QFUQ01CQLZA unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagcccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +13530 JY8QFUQ01BCDCV No results +13531 JY8QFUQ01C92CT productive Homsap IGHV3-21*04 F 869 88.99 194/218 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGHSYYVSSGPDYW in-frame + cctctggatttaccttcagtctctatagaatgaactgggtccgccaggctccagggaagggactggagtgggtctcatccattactagtaccagtagttacatttattatgcagacccagtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +13532 JY8QFUQ01DAV2P productive Homsap IGHV3-33*04 F 833 87.16 190/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGNGYSYDDVVARWFDSW in-frame - cttctggattcaccttcagtaattacgcaatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagtgacacgatatgacggagattataaattttatgctgactccgtgaagggccgcttcaccatttccagagacaattacaggaacaccctatatcttcaaatgaataacctgagagtcgaggacacggctgtctactactgtgcgcgaggaaatggatacagttatgatgacgtggtcgcgaggtggttcgactcctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13533 JY8QFUQ01BWN2X productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 974 93.67 207/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 2 10 7 12 10.7.12 [1.17.38.11] CVRHRRLELLPDYW in-frame + tctctagtgactccatcagcagtactaattactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatgtatcatggtgggagcacctactacaacccgtccctcgagagccgagtcaccatatccgtagatacatccaggaaccagttctccctgaagctgaggtttgtgaccgccgcagacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13534 JY8QFUQ01CSZL1 productive (see comment) Homsap IGHV3-9*01 F (see comment) 788 84.86 185/218 nt 83.49 182/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [2.17.37.11] CVKDMVAGQGLLSRFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 52 of V-REGION: 'GA' (2 nucleotides at position 70 to 71 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 113 in the user submitted sequence), (cause frameshift) gcctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagGAtgggtcgcgggcaGtcaactggaatcggggcaaagcattgtatgggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13535 JY8QFUQ01A5BMO No results +13536 JY8QFUQ01DT6YR No results +13537 JY8QFUQ01BELBS No results +13538 JY8QFUQ01B5NIQ No results +13539 JY8QFUQ01C3V22 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 960 93.18 205/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [2.17.38.11] CARGGLEPVDYW in-frame - gccctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13540 JY8QFUQ01AIT6H productive (see comment) Homsap IGHV3-9*01 F 1027 96.8 212/219 nt 96.35 211/219 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [2.17.38.11] CAKGDSGGYTHNYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaaggGgcctggagtgggtctcaggtattagctggaatagtggtagtatagggtatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattactgtgcaaaaggggatagtggtggttatacccacaactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13541 JY8QFUQ01AWOCC productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13542 JY8QFUQ01BY2IV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 720 81.57 177/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CAKVKGYGGNWFQPHFDRW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattctccttcgaggggtctgtcgtgacctgggtccgacaggctccagggaaggggctggagtgggtctcaggtatctacggtggtgatggtacatcattttacgcagacttcgcgaagggccgattcaccgtctccagagacaattccaaggacacggtctatctgcagatgaacggcctgagagtcgaagactcggcccgttattattgtgcgaaagtgaagggctacggcggcaattggttccagcctcactttgaccgctggggccagggcaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13543 JY8QFUQ01BHK6B productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13544 JY8QFUQ01BCXZT No results +13545 JY8QFUQ01AUWU9 No results +13546 JY8QFUQ01ATWGG productive Homsap IGHV3-11*01 F 828 87.1 189/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CVREVTGVWDWFDPW in-frame + ctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13547 JY8QFUQ01C5S8U productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13548 JY8QFUQ01AMWJR productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-20*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASLNTHAGPGAERSAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 79 of V-REGION: 'G' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtaactatagaatgaactgggtccgtcaggctccagggaaggggctcgaatgggtctcgtccatcaccagttccagtgcttacatctactatgcagactcggtgacgggccgattcaccatctGccagagacaacgccaaggggtcactctatctgcacatcaacgaccttagggccgaggacacggctgtctattactgtgcgagtcttaacacgcacgcgggaccgggagccgagaggtctgcttttgatatctggggccgagggacaatggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13549 JY8QFUQ01AD4KE productive (see comment) Homsap IGHV4-61*02 F 893 89.59 198/221 nt 88.69 196/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [2.16.38.11] CAREHSRTMGGARELDSW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'T' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift) gtctctggtggccccatcagcagcagcacttactactggacttggatccggcaggccgccgggagggactggagtggatcggacgtgtttatactTagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13550 JY8QFUQ01B1PWD unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ2*01 F (see comment) 76 60.38 32/53 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13551 JY8QFUQ01BTLMP productive Homsap IGHV4-30-2*03 F, or Homsap IGHV4-39*01 F or Homsap IGHV4-39*05 F 674 91.3 147/161 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 2 X 7 13 X.7.13 [X.8.38.11] CARCGSYGSGSYYPW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ggaagggcctggagtggattgggagtatgttttatactggggtcaccttctacaacccgtccctcaagagtcgagttaacatttccgtggacacgtcgaagagccagttctccctgaggctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagatgtggttcttatggttcggggagttattatccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13552 JY8QFUQ01CXOIY unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 169 57.86 81/140 nt 10 7 X 10.7.X [1.17.11.X] null - No rearrangement found stop codons ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13553 JY8QFUQ01DUJ59 productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13554 JY8QFUQ01C39LJ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARNELPWDTREYYFDYW in-frame - gtctggattcaccttcagtagctacggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13555 JY8QFUQ01BX74W productive (see comment) Homsap IGHV4-59*04 F (see comment) 729 82.03 178/217 nt 79.72 173/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 7 12 8.7.12 [2.17.38.11] CARRHYGEGLFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'CCCAATGAA' (9 nucleotides at position 22 to 30 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'TGG' (3 nucleotides at position 42 to 44 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'CAT' (3 nucleotides at position 67 to 69 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'C' (1 nucleotides at position 171 to 171 in the user submitted sequence), (cause frameshift); gtcctttggtggctccatcagCCCAATGAAtaattacttccTGGggcgtggagtccgccaggccccCATgggaaggggcctggagtggattCggggatgtccagtatagtgggagcacctactccagcccgtccctcaagaggcgggtcaccatgtctgtggacgtgtccCaaaagtcaggtctccctgagactgagctctgtgaccgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13556 JY8QFUQ01ABAG4 productive (see comment) Homsap IGHV3-7*01 F 810 86.18 187/217 nt 84.79 184/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [1.17.38.11] CARGDGYNFGGLDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'TGG' (3 nucleotides at position 64 to 66 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 75 of V-REGION: 'C' (1 nucleotides at position 133 to 133 in the user submitted sequence), (cause frameshift); ctctggatttagctttagaaccttttggatgagctgggtccgccaggctccaggggaggggcgTGGagagtgggtggcCcaacataaagtcagatggaagtgacaaatggtatgtggactccgtgaggggccCgatccatcatttccagagacgattctaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13557 JY8QFUQ01CT1B6 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame + tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttc +13558 JY8QFUQ01CX9R2 productive (see comment) Homsap IGHV4-4*07 F 859 88.89 192/216 nt 87.96 190/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 7 9 8.7.9 [2.17.38.11] CARDSGDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'A' (1 nucleotides at position 206 to 206 in the user submitted sequence), (cause frameshift); gtctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtccaaaccagtgggagccCcccactacaacccttccctcaagagtcgagtcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccActttttttctgtgcgagagactccggggactttgactactggggcccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13559 JY8QFUQ01BFRD4 No results +13560 JY8QFUQ01AA2UH No results +13561 JY8QFUQ01ANGEF productive Homsap IGHV4-4*07 F 817 87.32 186/213 nt Homsap IGHJ3*02 F 160 80.0 40/50 nt Homsap IGHD3-22*01 F 2 8 7 11 8.7.11 [1.17.38.11] CAGRNGNLAFNIW in-frame + tctggtggttcgatcgtcagttactactggagttggatccggcagtccgccgggaagggactggagtggattgggcgcatctactccaatggagatacgaactacaatccctccctcaagggtcgagtcaccatgtcagtagacccttccaacaaccagttctccctgaaattgacttctgtgaccgccgcggacacggccatatattactgtgcgggaagaaatggaaatttggccttcaatatttggggccaagggacaaatgtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13562 JY8QFUQ01BP4DE productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13563 JY8QFUQ01C4G5G productive (see comment) Homsap IGHV3-7*01 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.37.11] CARGSYWHYDTFGDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 77 of V-REGION: 1 nucleotides (from position 136 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcacatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13564 JY8QFUQ01C3M39 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 900 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [1.17.38.11] CNTDLGGSWYTFYSDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 59 of V-REGION: 6 nucleotides (from position 89 in the user submitted sequence), (do not cause frameshift) ctctggatacactgtcataaatgcctggatgagttgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaggtgatggtgtgacaacagaatacgctgcatccgtgaaaggcagattcaccatcacaagagatgactcaaggaacacgttgtatctacaaatgaacagcctgaaaaccgaggacacagccatatattattgcaacacagatctgggcgggagttggtacaccttctattctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13565 JY8QFUQ01DA81V No results +13566 JY8QFUQ01CKX1I productive Homsap IGHV3-9*02 F 837 87.56 190/217 nt Homsap IGHJ2*01 F (see comment) 157 77.36 41/53 nt Homsap IGHD4-11*01 ORF 3 8 8 17 8.8.17 [1.17.38.11] CARAPSVTFSGQGHYYDLW in-frame - Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cactggattcagctctgagaattatgccatgcactgggtccggcagcctccagggaagggcctagagtgggtctcacacatcagttggaatggcgaaggcatcgactacgcggactcagtgaagggccgattcaccgtctccagagacaacggcaagaattccctgtatttgcaaatgaacagtctgacaactgacgacacggccttgtattactgtgcaagagccccttcagtcacattcagcgggcaggggcactactatgatctctggggccgtggcaccctggtcgtggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13567 JY8QFUQ01DW642 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 458 88.79 103/116 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 2 X 0 14 X.0.14 [X.X.38.11] CPTPQNHDYIWGYDYW in-frame + tctggattcagcactccgtgaagggccgattcaccgtctccagagacaattccaagaacaccctgtatcttcaaatgaacagcctgagagccgaggacacggccgtgtattactgtccgaccccccagaatcatgattacatttggggctatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13568 JY8QFUQ01DGNK9 No results +13569 JY8QFUQ01AIAC1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.24 202/219 nt 91.78 201/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [2.17.38.11] CAKGYHGPFDSW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); gcctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacacatactactcagactccgtgaggGggccggttcaccatctccagagacaacgccaagaacacgatgtatctgcaaatgaacaccctgagagacgaggacacggccgtctatttctgcgcgaaaggttaccacggcccctttgactcttggggccggggaaccctggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13570 JY8QFUQ01CWH15 productive (see comment) Homsap IGHV4-61*01 F (see comment) 776 83.71 185/221 nt 83.26 184/221 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); tgtctggtggctccgtcagcagtggaaattcctactggacctTggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13571 JY8QFUQ01A1DDB No results +13572 JY8QFUQ01APR7P productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13573 JY8QFUQ01B5BIZ No results +13574 JY8QFUQ01CQG05 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*07 F 803 85.07 188/221 nt 84.62 187/221 nt Homsap IGHJ5*02 F 110 69.39 34/49 nt Homsap IGHD1-26*01 F 2 8 10 5 8.10.5 [1.17.37.11] CREAIAW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 160 in the user submitted sequence), (cause frameshift) tctgggttcgtgttcggtaacttctttatgaattggttccgccagcctccgggaaaggggctggagtgggttggccgcatcaaaaccaaagttgatggtgagacaacagactacgctgcagccgtgaaagacagattcatcatttcaagagatgattcaaaaatacgatgtatctgcaaatgaacgacctgaagaccgaggacacggccgtatattattgtcgggaggccatcgcgtggggccagggaaccctggtcaaggtctcatcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13575 JY8QFUQ01CTGHQ productive Homsap IGHV3-7*01 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + gctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13576 JY8QFUQ01CB5PE No results +13577 JY8QFUQ01AQGGH productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 979 93.69 208/222 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 8 10 15 8.10.15 [1.17.38.11] CATDRRGSTIAPQFDFW in-frame - tctggattcactttcagtagcgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaaacaaagctgacggtcagacaacagacttcgctgcacccgtgaaaggcagattcagcatctcaagagatgattcaaaaaccacactgtatctgcaaatgagcggcctgaaagccgaggacacagccatgtattactgtgccacagataggcggggttcgactatagcacctcaatttgacttctggagccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13578 JY8QFUQ01AMENX No results +13579 JY8QFUQ01AFH97 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 928 91.78 201/219 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-16*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARHNYGNEKYIMDVW in-frame - ggttttggatacaactttgccacctattggatcggctgggtgcgccacatgcccgggaaaggcctggaatggatggggatggtctttgctggtgactctgacaccagatacagtccgtccttccgaggccaggtcaccatgtcagccgacaagtccatcaacaccgcctacctgcagtggagcagcctgatggcctcggacaccgccatatattactgtgcgagacataattatggaaacgagaagtacattatggacgtctggggccaggggaccacggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13580 JY8QFUQ01APENP unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1030 97.69 211/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaagccctggctnaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +13581 JY8QFUQ01CK7GH unproductive Homsap IGHV3-48*02 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGEGDPFF##YYSGLDVW out-of-frame - in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagttaGtagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13582 JY8QFUQ01A91GC productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1046 97.29 215/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13583 JY8QFUQ01DEMZ0 unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGVVTA#LDYW out-of-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13584 JY8QFUQ01BNEB3 productive Homsap IGHV1-8*01 F 840 87.85 188/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARVGGTHYHYGVDVW in-frame + cggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagatctgacgacacggccgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13585 JY8QFUQ01CO34H productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 706 81.02 175/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [2.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame - Low V-REGION identity (81,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13586 JY8QFUQ01CPYSE No results +13587 JY8QFUQ01ALQUJ productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame - ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13588 JY8QFUQ01CS746 productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13589 JY8QFUQ01CV3MY unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ4*03 F (see comment) 123 72.92 35/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRRGW*RADMMLLIS# out-of-frame - stop codons Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaaggggatggtagcgggcagatatgatgcttttgatatctgggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13590 JY8QFUQ01CZFA8 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 2 9 7 11 9.7.11 [1.17.38.11] CARASTLRYLDRW in-frame - tctctggtggctccatcagcagtgataattggtggagttgggtccgccagcccccagggaagggactggaatggattggggaaatatatcatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacaagtccaagagtcaattcttcctggagctgaggtctgtgaccgccgcggacacggccgtatattattgtgcgagagcctccacactacgatatcttgaccgctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13591 JY8QFUQ01CSZXL unproductive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F (see comment) 525 71.5 153/214 nt 71.03 152/214 nt Homsap IGHJ4*03 F (see comment) 123 72.92 35/48 nt Homsap IGHD3-3*01 F 1 8 7 X 8.7.X [1.17.38.11] LDAFDI# out-of-frame + Low V-REGION identity (71,50% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 60 of V-REGION: 9 nucleotides (from position 92 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttaatagctttgccatgagttgggtccgccaggcttccgggaaaggactggagtgggttggccgtgtcggaaggcagggcgcgacaacatacgctgcgtcggtgaaaggcaggttcctcatctccagagatgatccagcgaacacggccgtctattactgtgctcgcgcagattactatgatactagtgcttattatctcgatgcttttgatatctgggccaggggacaattgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13592 JY8QFUQ01CE8T4 productive Homsap IGHV1-58*01 F 876 90.19 193/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD5-12*01 F 3 8 8 16 8.8.16 [0.17.38.11] CAASASYNGYDTDAFDIW in-frame + tggattcacctttgattcctctgctgtgcagtgggtgcggcaggctagtggacaccgccttgagtggatgggatggatcgtcgttgccaatggtaagacagactacgcacggaatctccagggaagagtcaccattgccagggacatgtccacaagtacagtctacatggagctgagcagcctgaaatccgaggacacggccgtatattactgtgcggccagtgcttcgtataatggctacgatactgatgcttttgatatctggggcgaagggacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +13593 JY8QFUQ01DADW2 productive (see comment) Homsap IGHV3-48*01 F (see comment) 754 84.04 179/213 nt 82.63 176/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 82 in the user submitted sequence), (do not cause frameshift) tctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaAagggctggagtGgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13594 JY8QFUQ01C7KS3 productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [0.17.38.11] CATDRCTGGTCCPHYW in-frame + tggatacactttcaccagttattatatacactgggtgcgacaggcccctggacaggggcttgagtggatgggagttgtcaaccctggtgctgaatacacactctacgcacagaagttccagggcagactcaccttgaccagggacacgtccacgagcacagtctacatggagttgagtagcctgagatctgaggacacggccctgtattactgtgcgacagataggtgtactggtggtacctgctgtccacattactggggccagggaaccctgatcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13595 JY8QFUQ01BTXVH No results +13596 JY8QFUQ01CEKIT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [2.17.38.11] CVRRGMVAGRYDAFDIW in-frame - gcctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +13597 JY8QFUQ01A35NF productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt 88.69 196/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcCccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13598 JY8QFUQ01C2L8V productive (see comment) Homsap IGHV3-11*01 F 928 93.81 197/210 nt 91.9 193/210 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.16.37.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 92 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccaggaagggactggagtggtttcatgcatcactactagtggtaccacattctacacggactctgtgagggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13599 JY8QFUQ01AF28W productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 671 78.44 171/218 nt 77.98 170/218 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIVREGLDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (78,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); tgtctggtggctccatcgccacttatcattggtggaattgggtccgccagAccccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13600 JY8QFUQ01A4LRU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13601 JY8QFUQ01A6CVK productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CGKPIVGATGREMPVSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) cctctggattcacctttagcGaactatgccatgaactgggtccgccaggttccagggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13602 JY8QFUQ01BKQCQ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 677 95.3 142/149 nt 94.63 141/149 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 1 8 8.1.8 [1.1.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01BKQCQ ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 40 of V-REGION: 68 nucleotides (from position 33 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtagctactggatgcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +13603 JY8QFUQ01AP4OP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 1 8 8 18 8.8.18 [1.17.38.11] CAKVLAGATRDAYHYGMDVW in-frame + ctctggatttactttcagtaggtctgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggcattagtggtggtggtcttagcacatactacacagactccgtgaagggccggttcaccatctccagagacatttccaagaacacgctgtttctgcaaatgaacagcctgagagccgaggacacggccacatattactgtgcgaaagtcctggcgggagctacgagggacgcctaccactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13604 JY8QFUQ01CX1W7 No results +13605 JY8QFUQ01BL5VZ productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctGggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13606 JY8QFUQ01CFJEW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame - ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13607 JY8QFUQ01DT6BL productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*07 F 818 85.27 191/224 nt 84.38 189/224 nt Homsap IGHJ5*02 F 110 69.39 34/49 nt Homsap IGHD1-26*01 F 2 8 10 5 8.10.5 [1.17.38.11] CREAIAW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift); cctctgggttcgtgttcggtaacttctttatgaattggttccgccagcctccgggaaAaggggctggagtgggttggccgcatcaaaaccaaagttgatggtgagacaacagactacgctgcagccgtgaaagacagattcatcatttcaagagatgattcCaaaaaatacgatgtatctgcaaatgaacgacctgaagaccgaggacacggccgtatattattgtcgggaggccatcgcgtggggccagggaaccctggtcaaggtctcatcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13608 JY8QFUQ01A9RBF productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKSPSQVGYYLDCW in-frame + ctctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccggcaaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcaccatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13609 JY8QFUQ01AA57U productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 725 81.65 178/218 nt 81.19 177/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDQYGSPSDFDNW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'GGA' (3 nucleotides at position 84 to 86 in the user submitted sequence), (do not cause frameshift); cctcagggttcgtttttgagaaatacgccatgagttgggtccgccaggctcccggaaaggggctggagtgggtctcggctattGGAggtgttgatgatgttggcacatactacgcagcctccgtgaagggtcggttcaccatatccagagacgattccagggagattctctatctacaaatgagtaacctgagagtcgacgatacggccgtctattactgtgcgaaagatcaatatgggagcccatccgactttgacaactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +13610 JY8QFUQ01C9SEI productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagGaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13611 JY8QFUQ01CZY8Q productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 965 95.28 202/212 nt 94.34 200/212 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [X.17.37.11] CASAPSDSSGYYFSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'GA' (2 nucleotides at position 51 to 52 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 120 in the user submitted sequence), (cause frameshift) ggatacaccttcaccagttactatatgcactgggtccgacaggcccctggGAccaagggcttgagtggatgggaatgatcaaccctagtggcggaagcacaatctacgcacagaacttccaggcagagttgccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgctagcgccccctctgatagtagtggatactacttttcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13612 JY8QFUQ01CB2QO productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13613 JY8QFUQ01DOJJL No results +13614 JY8QFUQ01B1WH0 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 947 92.31 204/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARQSFDFAWQWQVDYYFEYW in-frame + tctctggtggctccgtcagcagtagcacttactactggggctggctccgccagtccccagggaaggctctggagtggattgggactatccatcatagtgggagcacctaccagaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaggaaccagttctccctgaggctgagctctgtgaccgccgcagacacggctctttattactgtgcgagacaaagctttgatttcgcgtggcagtggcaggtagattattactttgaatactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +13615 JY8QFUQ01BWJBZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaagctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcgaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13616 JY8QFUQ01AAQPQ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13617 JY8QFUQ01CRB82 No results +13618 JY8QFUQ01ATWCJ productive (see comment) Homsap IGHV3-30*01 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 7 11 8.7.11 [1.17.38.11] CACGHMRDGYDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +13619 JY8QFUQ01DB4VJ unproductive Homsap IGHV3-21*04 F 963 94.01 204/217 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGYSYGCFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcagttttgcagactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagaggatacagctatggctgctttgactactgggggccagggaatcctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +13620 JY8QFUQ01BZ1C1 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKEQEPHGHYVGTDY## out-of-frame + cgtctggattcaccttcagtagctacggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggccgtgtattcctgtgcgaaagaacaagaaccacatgggcattatgttggaactgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgccgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13621 JY8QFUQ01BIGXB productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame - Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13622 JY8QFUQ01CPBDD productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13623 JY8QFUQ01C8O27 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13624 JY8QFUQ01B65ND productive Homsap IGHV3-48*01 F 1075 99.54 215/216 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASIFGVVPLGNYYYGMDVW in-frame - tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13625 JY8QFUQ01C065V productive Homsap IGHV3-11*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13626 JY8QFUQ01B96WH productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CATSPSDFDRRWGYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggatttagctttagaaccttttggatgagctgggtccgccaggctccagggagggggctggagtgggtggccaacataaAagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13627 JY8QFUQ01DLC24 productive (see comment) Homsap IGHV4-61*01 F 1105 100.0 222/222 nt 99.55 221/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [2.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); gtctctggtggctccgtcagcagtggtagttactactggagctggatccggcagAcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13628 JY8QFUQ01BYP3F productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CTRVGTFNWFGPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'T' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatTgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13629 JY8QFUQ01A8LX1 productive (see comment) Homsap IGHV3-9*01 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD3-22*01 F 2 7 8 26 7.8.26 [1.17.38.11] CVKDHGVTYFYDSVGYVSGAYNYAMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) ctctggattcacctttgatgatttggcatgcactgggtccggcaagttccagggaagggcccggagtgggtcgcaggtattagttggaatggtggacatatggactatgcggactctgtgaagggccgattcaccgtgtcccgagacaacgccgagaattccctgtatctgcaaatgaacagtctgacacctgaagacacggccctgtattactgtgtaaaagaccatggcgtcacttacttttatgacagtgttggttatgtctccggggcgtacaactacgcaatggacgtctggggccaggggacgacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13630 JY8QFUQ01B09S5 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13631 JY8QFUQ01AHST6 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13632 JY8QFUQ01DP225 productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13633 JY8QFUQ01CZ0CN unproductive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSGFTRR#YW out-of-frame - ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc +13634 JY8QFUQ01BD4S4 productive (see comment) Homsap IGHV3-11*01 F (see comment) 794 84.62 187/221 nt 84.16 186/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARYRGSYYDYGGVDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); caacctctggcttcagattccgtgactactacatgacgtgggtccgccaggctccagggaagggtcttgagtggctttcctccatcagcagcggtagtaataccatccactactcagactcggtgaggGggccgcttcaccatctccagggacaacaccaggaactcagtggatctgcaaatgaatagtctgagagccgaagacacggccgtctattattgtgcgaggtacagaggcagttactacgactatggcggtgtggacgtctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13635 JY8QFUQ01CO82S productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13636 JY8QFUQ01CXXPG productive (see comment) Homsap IGHV4-39*02 F 978 94.09 207/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.16.38.11] CARIVVRQFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtgactccatttccagtactagttattactggggctgggtccgccagccccagggaaggggctggagtggaTttgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13637 JY8QFUQ01AER3H No results +13638 JY8QFUQ01DNGXY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame - gcctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13639 JY8QFUQ01DDVRU No results +13640 JY8QFUQ01DL13S No results +13641 JY8QFUQ01DVVB9 No results +13642 JY8QFUQ01DPEHK productive (see comment) Homsap IGHV3-48*01 F 1090 100.0 219/219 nt 99.09 217/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) agcctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13643 JY8QFUQ01BKJ38 productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13644 JY8QFUQ01B4O24 productive (see comment) Homsap IGHV3-7*01 F 1027 96.8 212/219 nt 96.35 211/219 nt Homsap IGHJ6*02 F (see comment) 188 78.69 48/61 nt Homsap IGHD6-13*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARERQLNNGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtagctattggatgagctgggtccgccaggctccagggaaggggctggagtGgggtgacccacataaagcaagatggaagtgtcaaataccaagtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagagcggcagcttaataacggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13645 JY8QFUQ01BTJ5H productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 927 92.17 200/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13646 JY8QFUQ01BFOPH unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 849 88.79 190/214 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F (see comment) 29 69.23 9/13 nt 8 8 X 8.8.X [0.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tggatacaccttcagcaacttctatatatattgggttcgacaggcccctggacaagggcttgattacataggagtattcaaccctagtggtggtaacaccaggtacgcacagaagttccaggacagagtcaccgtgaccagtgacacgtccacgaacacagtgtacatggagctgagtaggctgagatctgaagacacggccgtgtattactgtgcgagagggatagtggttactctgaatcggaaagtccgacaacccccaaaagactactgggggccagggaaccccgggtcatcgtctcctcagcttccaccaagggcccatccgtcttcccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13647 JY8QFUQ01BYIOI productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13648 JY8QFUQ01C6ALY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaacGaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13649 JY8QFUQ01C76AE productive (see comment) Homsap IGHV3-7*01 F 946 92.24 202/219 nt 91.78 201/219 nt Homsap IGHJ1*01 F (see comment) 107 67.31 35/52 nt Homsap IGHD5-12*01 F 2 8 8 10 8.8.10 [2.17.38.11] CSLGAGWLTPHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); gcctctggattcgcAttttagtacctattggatgaactgggtccgccaggttccggggaagggcctggagtgggtggccatcataaagcaagatggaagtgacatatcctatgtggactctgtgatgggccgattcaccatctccatagacaacgccaagaattcagtgtttctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgctctttaggcgctgggtggctaacaccacattgggggcggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaacttcag +13650 JY8QFUQ01BANFC No results +13651 JY8QFUQ01AVFPO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 847 87.67 192/219 nt 87.21 191/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CTRDIGGRYSY## out-of-frame - in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift); gcctctggattcatctttagtaattatgccatgagttgggtccgccaggccccagggagggggctggagtgggtctcaactatcagtgccaatggagacaacacaaAactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13652 JY8QFUQ01ABFMY unproductive (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F (see comment) 413 80.8 101/125 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 X 3 X X.3.X [X.X.38.11] CASFAGPVVVTL*WLLVRLT#YCDYR out-of-frame + stop codons Low V-REGION identity (80,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgcattcaccgtcagtaggctccgtgacgggccgagtcatcatctccagagagaatgcccagaactccgtgtatcttccactgaacagcctgagagccgggaacacggctgtgtatcactgcgcaagttttgctggccctgtggtggtgactctatagtggctgttggtccgtctgaccactactgtgactaccggggcctgggaaccccggtccccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13653 JY8QFUQ01BSX5W unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1110 100.0 223/223 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFFGLL# out-of-frame + stop codons ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttcccccttggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13654 JY8QFUQ01CH14U No results +13655 JY8QFUQ01ARLEN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 960 93.18 205/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARETLPLGVGGFDNW in-frame - agcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13656 JY8QFUQ01C0QKA unproductive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13657 JY8QFUQ01CBO1C No results +13658 JY8QFUQ01BGJUC productive (see comment) Homsap IGHV1-2*02 F 939 93.46 200/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 82 to 87 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13659 JY8QFUQ01DJ3QI productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYYHYDMFGDYW in-frame + cgctggatttacttttagcaactattggatgacctgggttcgccaggctccagggaaggggctggagtgggtggccaacataaaacaacatggaggtgaaatgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgcatctgcaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgagagggtcgtattatcattatgatatgttcggcgactactggggccagggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +13660 JY8QFUQ01DQMDP No results +13661 JY8QFUQ01CQQPS unproductive (see comment) Homsap IGHV4-61*02 F 1005 95.45 210/220 nt 94.55 208/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 2 10 7 X 10.7.X [1.16.38.11] CARAGETGLFGVVI#DDW out-of-frame - stop codons in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tctctggtggctccatcggcagtggtagttattactggagctggatccgcagcccgccgggaagggactggaataccttgggcgtatctataccagtgGggagcaccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgctgacacggccatttattactgtgcgagagcgggggaaacaggactttttggagtggttattctgacgactggggccagggaaccctggtcatagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13662 JY8QFUQ01BGOPQ productive Homsap IGHV3-13*01 F 872 89.77 193/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-21*02 F 3 8 7 9 8.7.9 [1.17.38.11] CARDQVTEDYW in-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +13663 JY8QFUQ01A688N productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13664 JY8QFUQ01BMP31 No results +13665 JY8QFUQ01B98BJ productive (see comment) Homsap IGHV3-7*01 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) cctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttagacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13666 JY8QFUQ01AGY03 No results +13667 JY8QFUQ01AWR6X No results +13668 JY8QFUQ01B28RE No results +13669 JY8QFUQ01BSR1C productive Homsap IGHV3-48*01 F 923 91.74 200/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTRQTGNYYYFGVDVW in-frame - cctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13670 JY8QFUQ01B6BOW productive Homsap IGHV3-21*04 F 990 95.39 207/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame + ctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13671 JY8QFUQ01C6MOM unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 536 71.56 156/218 nt Homsap IGHJ1*01 F (see comment) 22 75.0 6/8 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (71,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctgggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +13672 JY8QFUQ01C3EQE productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattCaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13673 JY8QFUQ01CSECT productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13674 JY8QFUQ01CATOK productive Homsap IGHV4-59*03 F 935 93.02 200/215 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD3-22*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARGLYYYTSGYPHDAFDVW in-frame - tctctggtgactccatcaatgcttactattggagctggattcggcagtccccagggaagggactggagtggattggacatgtctattatagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacatatccaagaaccaattctccctgaagctgaactctgtgaccgctgcggacacggccgtgtatcactgtgcgcgggggctctattattatactagtggttatccccatgatgcttttgatgtctggagccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13675 JY8QFUQ01DG853 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*02 F 1 8 8 14 8.8.14 [1.17.38.11] CAKVGLMSARDRIDYW in-frame + ctctggattcacctttagcaactatgccatgagttgggtccgccaggctcaagggaaggggctggactgggtctcagatattagtaatagtggtggtgacacattctacgcaggctccgtgaagggccgcttcaccatctccagagacaattccaggaacactctatatctgcaaatggacagcctgagagccgaggacacggccgtgtattactgtgcgaaagtggggctgatgtccgctcgagaccgcattgactactggggccggggaaccctggtctccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13676 JY8QFUQ01C1AIH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [1.17.38.11] CAKEGNLGYFDDW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +13677 JY8QFUQ01BB93X productive (see comment) Homsap IGHV1-2*04 F 925 92.96 198/213 nt 92.49 197/213 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 14 8.8.14 [0.17.37.11] CTRDTSLDNGAALDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) tggatacaccttcaccgactactatatgcactgggtgcgacaggccccaggacaagggcttgagtggatgggatggatcaaccctaaaagtggcggcacaaattatgcacggaagtttcaggctgggtcaccatgaccagggacacatccatcaacactgtctacatggagttgagcaggttgaaatctgacgacacggccatttattactgtacgagggatacttctttggacaacggagccgctcttgatatttggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13678 JY8QFUQ01CDRDD productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13679 JY8QFUQ01B832O productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 7 8 17 7.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) tctggattcagtttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgcctgctccaggagcactccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13680 JY8QFUQ01ADD9Y unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 96 95.24 20/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattcacctttagtac +13681 JY8QFUQ01BQMNN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13682 JY8QFUQ01BPXDU unproductive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CATSPFTVTTGKDAY## out-of-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggcccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13683 JY8QFUQ01CHKB6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKSPDFGGNP#YFDFW out-of-frame - ctctggattcgccttcaccagctatgccatgacctgggtccgccaggccccagggaaggggctggaatgggtctcttctattagtggcagtggtgcgaccacatactacgcagactccgtgaagggccgcttcaccacctccagagacaattccaagaacacggtgtatctgcaaatggacagcctgagagccgcggacacggccgtctattactgtgcgaaaagtcccgacttcggtggtaaccctcctactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13684 JY8QFUQ01BNQ6N productive Homsap IGHV3-23*03 F (see comment) 894 91.12 195/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [1.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BNQ6N ; 8 AA in Homsap_IGHV3-23*03) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttggttattatggcatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13685 JY8QFUQ01APK7S productive (see comment) Homsap IGHV4-34*06 F (see comment) 682 80.19 170/212 nt 79.72 169/212 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 7 7 14 7.7.14 [1.17.38.11] CSRGGQSAGWHSFEAW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 38 of V-REGION: 2 nucleotides (from position 27 in the user submitted sequence), (cause frameshift) tccatggtgggtccctcagggttaccctggacctggatccgccacaccgcagagaagggactggagtggattggtcaaatcaatagtgatggaaggacaacctacaactcggccctcatgggtcgagtcaccatttcaacagacacatccaagaatcagttctcgctgactgtggtttctgttgtcgccgcggacacggcaatgtattattgttcgagaggaggccaaagtgctggctggcactcctttgaagcctggggccagggaacccaggtaatcgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacctagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13686 JY8QFUQ01CV9Y0 No results +13687 JY8QFUQ01AGXFM unknown (see comment) Homsap IGHV4-61*02 F (see comment) 270 58.06 126/217 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (58,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtgggggtgtcgactacaacccctcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +13688 JY8QFUQ01AGMKR productive Homsap IGHV4-4*01 F, or Homsap IGHV4-4*02 F or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 873 89.4 194/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 2 9 7 14 9.7.14 [1.17.38.11] CARDKDVTARGTFDMW in-frame + ctctggtgtctccatcagtagtaattactggtggatttgggtccgccagtccccaggggaggggctggagtggattggagaagtctatcatactgggaccacctattacaacccgtccctgaagagtcgagtcaccctgtcagtagacaagtccaggaatcagttctccctggagatgacttctgtgaccgccgcggacacggccgtgtatttctgtgcgagagataaagacgtgacagctcgtgggacctttgatatgtggggccaggggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13689 JY8QFUQ01CNUO2 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13690 JY8QFUQ01ADNKP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [1.17.38.11] CVKDRDFLWGTYRLQLEHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'A' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); ctctggattcagatttagcagctatgccaAtgagctgggtccgccagactccagaaaaggggcttgaatgggtctcaggcatcaatgataacggtcgaagcataaactacgcgggctccgtgaagggccggttcaccatctccagagacaattccaagagcacgttgtatctgcagatggatagcctgagccccgaggactcgggcatatattattgtgtgaaagatcgtgatttcctttggggcacttatcgtcttcaacttgaacattggggccagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13691 JY8QFUQ01BS2U1 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'N' (1 nucleotides at position 137 to 137 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccNatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13692 JY8QFUQ01AN28Z No results +13693 JY8QFUQ01DIT1N No results +13694 JY8QFUQ01CHKF0 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [1.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) gttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13695 JY8QFUQ01AC5GC productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccgtcagcagtggtaattactactggaactggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13696 JY8QFUQ01BSDZV productive (see comment) Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt 79.72 173/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.37.11] CARDILDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 100 of V-REGION: 1 nucleotides (from position 204 in the user submitted sequence), (cause frameshift) catttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacgctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13697 JY8QFUQ01BERHM unproductive Homsap IGHV1-2*02 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [0.17.38.11] CARGGRRGNYYWGILTP# out-of-frame - in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); tggatacacgttcaccgactactatgtccactgggtgcgacaggcccctggacaagggcttgagtggatggcgtggatcaaccctaacattggtgtcaccaagtctgcacGaaaaatttcagggcagggtcaccatgaccagggacacgtccatcagcacagccttcatggagctgagcagcctgagatctgacgacacggccgtttattactgtgcgagaggggggcgacgtgggaactattattggggaatcttgactcctggggccaggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13698 JY8QFUQ01DKUF5 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 892 89.95 197/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) ggcctcctggattcacCctttggttattatggcatgactgggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13699 JY8QFUQ01C819B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKKHYNSGTYLYNFDYW in-frame + ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaaagcattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13700 JY8QFUQ01CE3GD unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [2.16.38.11] CTRTQFDPDYGDYETGYGMDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) gcggctggattcaacttccgatcttatgccatgtactgggtccgccaggcccaggcaaggggctggactgggtggcagttatttggcatgatggcagtaatcaatactatacagattccgtgaagggccgattcaccatctccagagacaattccaagaacacattgtttctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtacgaggacgcaatttgaccctgactacggtgactacgagacggggtacggtatggacgtctgggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13701 JY8QFUQ01CWV4R productive (see comment) Homsap IGHV3-48*02 F 628 94.33 133/141 nt 93.62 132/141 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 X 14 8.X.14 [1.2.35.11] CAKDRGGSAYPIFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 76 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) ctctggattcaccttcggcagttataggatgagctggactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13702 JY8QFUQ01B5K7F No results +13703 JY8QFUQ01C73WM unproductive Homsap IGHV3-74*03 F (see comment) 702 80.65 175/217 nt 80.18 174/217 nt Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRGTTGWRGVDY## out-of-frame - Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcaacgtcagtggatactggatgcactgggtccgccaagtgccagggaaggggctggtatgggtctctaggctttcggatgatgaaattactataacttacgcggactttgtggagggccgattcaccatctccagagacaacgccaggaacgaggtctatctgcaaatgaatgatttgagagtcgacgatacggctgtatacttttgtgtgaggggaaccactggctggaggggggttgactactgggggccaaggcgccctcgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13704 JY8QFUQ01BX8L0 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 602 91.61 131/143 nt 90.91 130/143 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 3 8 X 14 8.X.14 [2.2.35.11] CATDRLRGDKYNFDDW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 76 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagctataccttgagttggatgcagtgaagggccgattcaccatttccagagacaacgccaagaactccctctctctgcaaatgaacagcctgagagccgaggacacggcagtatattactgtgcgaccgaccgccttcgtggagataaatacaattttgacgactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13705 JY8QFUQ01AP7Z9 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); gcctccggattcaccGtttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13706 JY8QFUQ01BNNOK unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 859 88.02 191/217 nt 87.1 189/217 nt 8 8 X 8.8.X [2.16.38.X] null - No rearrangement found in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 176 to 176 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 2 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagctatagcatgaacgtggtccgccaggctccagggaaggggtgagtgggtctcatccattagtagtagtagtanttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaAatgaacaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13707 JY8QFUQ01AQQ0A productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 994 95.83 207/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - tctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13708 JY8QFUQ01DPB8X unproductive (see comment) Homsap IGHV4-55*03 P (see comment) 644 77.42 168/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD5-18*01 F 3 10 7 X 10.7.X [1.17.38.11] CARHSRLVRYFEF## out-of-frame + however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01DPB8X ; 9 AA in Homsap_IGHV4-55*03), and low V-REGION identity (77,42% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctgttgacgccataagcgacctcggttatttctgggcctgggtccgccagcccgccgcgaagggactggagtggatcggacatgcccttggtgatggatataccgaatacaaccccgccctagagagtcgaatcaccgtgtcagtggacaagtccaagaaccagttttccctgacgttggagtccgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggcccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13709 JY8QFUQ01BOGFB productive Homsap IGHV3-64*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAGDLTGVPYYYDSSGLKYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +13710 JY8QFUQ01B0WZ3 No results +13711 JY8QFUQ01B1TCN productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 846 88.02 191/217 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [2.17.38.11] CAREFRAPSLARYGMDVW in-frame - gcctcgggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcaatatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13712 JY8QFUQ01BALA1 No results +13713 JY8QFUQ01C80EU productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13714 JY8QFUQ01COICN unproductive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +13715 JY8QFUQ01BX0HR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKNRGSAMADWYFDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'ATG' (3 nucleotides at position 88 to 90 in the user submitted sequence), (do not cause frameshift); cctctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattactaATGgtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttatttctgtgcgaaaaatagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13716 JY8QFUQ01ALB0B productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 760 83.8 181/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame - Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13717 JY8QFUQ01CAGWR No results +13718 JY8QFUQ01BFDI8 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactcag +13719 JY8QFUQ01BCE7A productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 912 90.13 201/223 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD5-24*01 ORF 3 8 10 17 8.10.17 [1.17.38.11] CSRGLGDGYNLGYHALDIW in-frame - ttctggattcagttttggtgattattctatgatctggttccgccaggcaccggggaaggggctggagtgcgtaggtttcattagaagcagagcatatggtgggacaacacaatacgccgcgtctgtgaaagacagattcaccatctcaagagatgatcccaaaggcatcgcctatttgcaaatgagcagtctgaaagtcgacgacacaggcgtgtatttttgtagtcggggattaggcgatggctacaatctgggttatcatgcccttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13720 JY8QFUQ01BOEIY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttcccccag +13721 JY8QFUQ01DFZ5B No results +13722 JY8QFUQ01BG466 unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*05 F (see comment) 302 75.23 82/109 nt 8 10 X 8.10.X [1.17.X.X] null - No rearrangement found Low V-REGION identity (75,23% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcactttcagtgacgcctggatgagctgggtccgccagattccagggaaggggctggagtgggttggtcgtcgcatgcctggtccagggcttcttccccca +13723 JY8QFUQ01B9KLC No results +13724 JY8QFUQ01CD5QQ No results +13725 JY8QFUQ01ACV4H productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + cgtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +13726 JY8QFUQ01DAB4Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKKHYNSGTYLYNFDYW in-frame - ctctgggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaacattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13727 JY8QFUQ01B6QSK unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 455 87.29 103/118 nt 8 8 X 8.8.X [1.17.4.X] null - No rearrangement found cctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcttccccca +13728 JY8QFUQ01A4IQR productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 903 91.59 196/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARRDVGSHAFDLW in-frame - tggatacaattttaactacgactggatcggctgggtgcgccagatgctcgggaaaggcctggagtggatggggatggtctatgttggtgactctgatgctagatacagcccgtcctccgaaggccaggtcaccatctcagccgacaaggccatcagtaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggatgtgggttcacatgctttcgatctgtggggccaagggacaatggtcaccgtttcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt +13729 JY8QFUQ01COLCX productive (see comment) Homsap IGHV3-7*01 F 926 92.56 199/215 nt 92.09 198/215 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 7 9 8.7.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame + Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 81 in the user submitted sequence), (cause frameshift) tctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggaggggcgtggagtgggtggccaacataagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +13730 JY8QFUQ01BYTJB productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13731 JY8QFUQ01AVB8N productive (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P (see comment) 737 82.79 178/215 nt 82.33 177/215 nt Homsap IGHJ6*02 F (see comment) 211 82.26 51/62 nt Homsap IGHD6-6*01 F 1 8 8 21 8.8.21 [1.17.38.11] CAKDLGYSISSGASTHYYGMGVW in-frame - Potentially, because of detected insertion/deletion however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01AVB8N ; 7 AA in Homsap_IGHV3-69-1*01), and low V-REGION identity (82,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); cctctggattcgcctTttggtgactatgccatgaactgggtccgccaggctccagggaggggcctggaatgggtctcatttgtcaccactactggcagttccacatattatgcagactccgtgaagggccgattcaccgtttccagagacgacgccaagaatctactgtatcttcagatgaccggcctgagagacggggacacggctacatattactgtgcgaaagacttggggtacagcatctcgtcgggggcctccacgcactactacggaatgggcgtctggggccaagggacaacggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13732 JY8QFUQ01CO8FJ productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 955 91.23 208/228 nt 90.79 207/228 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 19 10.9.19 [2.17.38.11] CARASRRDRLSDKNYYELDFW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 133 to 133 in the user submitted sequence), (cause frameshift); tctccgggggacagtgtctctagcaacagtgccacttggagctggatcaggcagtccccaacgggacgccttgagtggctgggaaggacttactacaggtccaaatggtataatgattatgcggtgtctgtgAaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcaattgaactccgttagtcccgaggacacggctgtgtattactgtgcaagagcttccagacgcgatcgtctctctgataagaactactatgaactggacttctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcacgcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +13733 JY8QFUQ01CXM37 productive Homsap IGHV1-24*01 F 988 96.24 205/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame - ggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13734 JY8QFUQ01AFSQR unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGV*QWL##DFDCW out-of-frame - stop codons in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); tctggattcacctttagtagatttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtcGtcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13735 JY8QFUQ01A7137 No results +13736 JY8QFUQ01CYX8Z No results +13737 JY8QFUQ01AP7QS unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDLRGSTMASD#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaaggggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13738 JY8QFUQ01BG66A productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13739 JY8QFUQ01BLP66 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 973 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcCgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13740 JY8QFUQ01CJAOV productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARFSGSYKSAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); gttctggatacatctttaccgactattggatcggctgggtgcgccagacggccgggaaAaggcctggagtggatggggaAtcatctatcctggtgactctgacaccagttatggcccgtccttccaaggccaggtcaccatttcagccgaccagtccatcaccaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagattcagtgggagttacaaatcggcttttgatatctggggccgagggacaatggtctccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13741 JY8QFUQ01A129D No results +13742 JY8QFUQ01DCH36 No results +13743 JY8QFUQ01B2TNY unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F (see comment) 264 72.38 76/105 nt 8 8 X 8.8.X [0.17.1.X] null + No rearrangement found Low V-REGION identity (72,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcaccgaccactatctgcactgggtccgacaggcccctggacaagggcttgagtggatgggaacgtggtcatcgcctgcctggtccagggcttc +13744 JY8QFUQ01B3AED unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaaggggaccacggtcaccggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13745 JY8QFUQ01BG866 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ5*02 F 109 70.21 33/47 nt Homsap IGHD5-12*01 F 3 8 8 6 8.8.6 [1.17.38.11] CVSIGHGV in-frame + cctctggattcgcctttaggagtgagtggatgaactgggtccgccaagccccagggaaggggctggagtgggtcgcacacattgacactgatgggagtatcgcagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaatactttgtatctgcaaatggacagtctgagagccgacgacacggctatatattactgtgtaagcattggacacggagtgggcccgggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +13746 JY8QFUQ01CI9RK No results +13747 JY8QFUQ01BIN5M No results +13748 JY8QFUQ01BAD9W productive (see comment) Homsap IGHV3-30*01 F 996 95.0 209/220 nt 94.55 208/220 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [2.17.38.11] CAKDELPWDTIEYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); ggcctctggattcaccttcaatacctattcGtatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13749 JY8QFUQ01DS5YQ unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 972 94.47 205/217 nt Homsap IGHJ3*01 F (see comment) 124 72.0 36/50 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKSPSQVGYYLD#VG out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccggcaaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcaccatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13750 JY8QFUQ01BHEWJ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13751 JY8QFUQ01C9UKO productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 801 85.71 186/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13752 JY8QFUQ01A2AVP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13753 JY8QFUQ01CKJ3B No results +13754 JY8QFUQ01BQSY3 productive Homsap IGHV3-33*04 F (see comment) 698 80.28 175/218 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release catttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctca +13755 JY8QFUQ01BCRG1 No results +13756 JY8QFUQ01DP380 productive Homsap IGHV3-33*02 F, or Homsap IGHV3-33*03 F 148 65.43 53/81 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 X X 14 X.X.14 [X.X.27.11] CATDDSNGWDEVADYW in-frame - gcctctggattcaccttcagctcccattggatgagctggatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13757 JY8QFUQ01DNJEO productive (see comment) Homsap IGHV3-7*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [2.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) gcctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13758 JY8QFUQ01CQIXM productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.49 197/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttTgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13759 JY8QFUQ01AZ08S productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 10 7 17 10.7.17 [1.17.38.11] CVRLDYYGSGSSYSGLDYW in-frame + tgtctggtggctccatcagtggtactccttactactggggctggatccgccagcccccaggtaaggggctggagtggattgggcatgtatatcacagagggaccacctactacaacccgtccctcaagagtcgagtcgccatatccgtagacacgtccgagaaccggttctccctgcagttgaactctgtgaccgccgcagacacggctgtatattactgtgtgagactggattactatggttcgggaagttcttatagtggccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +13760 JY8QFUQ01DLTW9 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13761 JY8QFUQ01BMYZK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13762 JY8QFUQ01BAGOW productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 928 89.91 205/228 nt 89.47 204/228 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 3 10 9 19 10.9.19 [2.17.38.11] CARSSRRDRLSDRNYYELDFW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 133 to 133 in the user submitted sequence), (cause frameshift); tctccgggggacagtgtctctagcaacagtgccacttggaactggatcaggcagtccccaacgggaggccttgagtggctgggaaggacatactacaggtccaaatgggatactgattatgcggcgtctgtgAaaaagtcgaataaccctcaccccagacacatccaagaaccagttctccctgcaattgaactccgttagtcccgaggacacggctgtgtattattgtgcaagatcttccagacgcgatcgtttgtctgataggaactactatgagctggacttctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +13763 JY8QFUQ01CI3EW unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); cctccggattcaccGtttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13764 JY8QFUQ01CL0CL productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 689 79.82 174/218 nt 79.36 173/218 nt Homsap IGHJ6*02 F (see comment) 157 72.58 45/62 nt Homsap IGHD5-24*01 ORF 3 8 8 15 8.8.15 [2.17.37.11] CASGGNAYITRRGLEVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 170 in the user submitted sequence), (cause frameshift) gcttccggcttcaccctcagtaaacactggatgcattgggtccgccagccttcagggaagggcctggagtttgtcgcgcgtctgagtaatgatggatataccacaagttatgcagactccgtgcagggccgcttcactatctccagagacgccgccgcgaacgcgctgttttgcagttgaccggtctgagagccgacgacacgggtgtctattactgtgcaagtgggggaaatgcctacatcacgcggcgtggtctggaggtctggggccgggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13765 JY8QFUQ01CG4QN productive Homsap IGHV3-30*01 F 878 89.45 195/218 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [1.17.38.11] CACGHMRDGYDVW in-frame + cctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13766 JY8QFUQ01B4C0K productive Homsap IGHV3-7*01 F 1031 97.25 212/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaaatgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13767 JY8QFUQ01A9WD5 unproductive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSGFLLDG#YW out-of-frame - ctctggattcacctttgatgattatgtcatgcactgggtccggcaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtgggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13768 JY8QFUQ01AG5VW productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKNNNDFGDYDWFDPW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 90 to 95 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13769 JY8QFUQ01A7FPX productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc +13770 JY8QFUQ01DJUOR unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF or Homsap IGHV3-23*01 F or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 143 75.0 39/52 nt 8 X X 8.X.X [1.8.X.X] null - No rearrangement found ctcagggttcgtttttgagaaatacgccatgagttgggtccgccaggcccca +13771 JY8QFUQ01BB0UL No results +13772 JY8QFUQ01BQZSZ No results +13773 JY8QFUQ01CZ1K4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 861 88.18 194/220 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [2.17.38.11] CMNEFGYCSGG# out-of-frame - aggctctggattcacttttagcagccatatgatgacttgggtccgccaggctccagggaaggggctggaatgggtcgcaagtattcgtgccagtggtggtaggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgttgtatttgcaaatgtacagtctgagagtcgaggacacggccttatattattgtatgaacgaattcggatactgtagtggtgggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13774 JY8QFUQ01BAT4C productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13775 JY8QFUQ01DKRX5 productive Homsap IGHV3-7*01 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [0.17.38.11] CARVGYGYRGIYFFDYW in-frame - ctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13776 JY8QFUQ01B9UE1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13777 JY8QFUQ01BWLWN No results +13778 JY8QFUQ01C0Q01 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcaaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +13779 JY8QFUQ01CP0F3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13780 JY8QFUQ01AYACL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 784 84.47 185/219 nt 83.56 183/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); tgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13781 JY8QFUQ01B7Q4P productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cgtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggGggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13782 JY8QFUQ01CJTTF productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 7 12 8.7.12 [1.17.38.11] CARAPGWMNPFDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaccacttactacatcagctggctccggcagcCccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccga +13783 JY8QFUQ01ACMD4 No results +13784 JY8QFUQ01B0E0W productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt 94.93 206/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.16.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaagggctggagtggatttcatacattagtagtagtgGgtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13785 JY8QFUQ01BVNW1 productive Homsap IGHV4-34*13 F 1060 100.0 213/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 7 13 8.7.13 [1.17.38.11] CASRSRGYSYGYDYW in-frame + ctatggtgggtccttcagtggttactactggagctggatccgccagcccccagggaaggggctggagtggattggggaaatcaatcatagtggaagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagccgctcacgtggatacagctatggttacgactactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaaccc +13786 JY8QFUQ01ANI1H productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13787 JY8QFUQ01AREZ5 productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARELGGSGTCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); tggatacaccttcaccaggcactatatgcactgggtgcgacaggcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggGggcagagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13788 JY8QFUQ01DBD13 No results +13789 JY8QFUQ01BB9BO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + cctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagccaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +13790 JY8QFUQ01AQA3U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKCKAPGKVDWFDPW in-frame + ttctggattctcctttagcaactatgccctggcctgggtccgccaggctccagggaaggggctggagtgggtctcaattgttagtggaagtggtactggcacaggccacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctggtaaggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcgcgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +13791 JY8QFUQ01BPN3Y unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 805 85.65 185/216 nt 85.19 184/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 97 66.0 33/50 nt Homsap IGHD2-21*01 F 2 8 8 X 8.8.X [1.17.37.11] CARDNVTFWDAFDIW# out-of-frame - in FR3-IMGT, from codon 86 of V-REGION: 1 nucleotides (from position 163 in the user submitted sequence), (cause frameshift) gtctgggttaaccttcagtgaggatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagtcatttggaacaatggaaagacctttcactatgcagactccgtgaagggccgcttcgtcatctcccgagacaattccaagagcacctatatttacaaatgaatagcctgagagtcgaggacacggctgtgtattactgcgcgagagataatgtcaccttttgggatgcctttgatatttgggggccggggggacaacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13792 JY8QFUQ01CCFDS productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13793 JY8QFUQ01AKI3X No results +13794 JY8QFUQ01CR04E productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13795 JY8QFUQ01CH8DM unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGG# out-of-frame + ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13796 JY8QFUQ01AVTVF unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD3-16*02 F 3 8 7 X 8.7.X [4.17.38.11] CARGAPFS**# out-of-frame + stop codons cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaggggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13797 JY8QFUQ01CMG8J unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 874 93.03 187/201 nt 92.54 186/201 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-2*01 F 2 10 1 X 10.1.X [1.17.37.11] CARVA*CDFVVEPTAQGL#YSYDMDVW out-of-frame + stop codons in CDR2-IMGT, from codon 57 of V-REGION: 19 nucleotides (from position 90 in the user submitted sequence), (cause frameshift) ctctggtggctccatcaacaatagtacttactactacggctgaatccgccagccccccgggaaggggctggagtggattgggagtctctctacaacccgtccctcatgagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgccgacacggctgtatatcgctgtgcgagagttgcctgatgtgattttgtggtagagccaactgctcaaggccttagtactcctacgatatggacgtctggggccaagggaccacggacgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13798 JY8QFUQ01A2Q7N productive Homsap IGHV3-33*04 F (see comment) 698 80.28 175/218 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame - Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release catttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13799 JY8QFUQ01DWIOH productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 939 91.48 204/223 nt 91.03 203/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 2 8 10 9 8.10.9 [1.17.38.11] CNTWLGPSDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 75 of V-REGION: 'A' (1 nucleotides at position 134 to 134 in the user submitted sequence), (cause frameshift); ctctggattcactgtcaataacgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgatggcgggacagcagactacgctccatttgtggacgacAagattcaccatttcaacagatgattcaaaaaacacgttgtatctcctaatgaacagcctgaaaaccgaggacacagccgtctattactgtaacacctggctaggacctagtgactactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13800 JY8QFUQ01AFCKU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CANEVGYCSGGG in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaGggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13801 JY8QFUQ01A3O28 No results +13802 JY8QFUQ01BR32F productive Homsap IGHV3-7*01 F (see comment) 783 84.79 184/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARERSAAGVVFFDFW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaggggctggagtgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgcaaatgaacagcctgcgagtcgaggacacggctgtgtatttctgtgcgagagagagatcagcagctggagtcgtcttctttgacttttggggccagggagccccggtcaccgtctccagagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13803 JY8QFUQ01A5NHA productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-3*02 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ1*01 F (see comment) 80 61.54 32/52 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKRWAGGLAGTLSSG in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'A' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); gtctggattcagtttcagtgactatgccatgcactgggtccgccagactccaggcaaggggctggagtgggtggcagttatttcatatgatgggagagagaagtactatgcagactccctgaagggccgattcaccacctccagagacaactccaagAaaaatgctgtatctccaagtgaatagcctgagacctggagacacggctgtgtattactgtgcgaaaagatgggccggggggttggctggtacgctgagcagtggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13804 JY8QFUQ01B2AOD No results +13805 JY8QFUQ01DIXL8 No results +13806 JY8QFUQ01CLQ5W No results +13807 JY8QFUQ01C8V86 unproductive Homsap IGHV4-61*03 F, or Homsap IGHV4-61*08 F 866 88.24 195/221 nt Homsap IGHJ5*01 F 84 62.75 32/51 nt Homsap IGHD5-24*01 ORF 2 10 7 X 10.7.X [1.17.38.11] CARLRRMVPVSTYYYHSLDV## out-of-frame + tctccggtgcctccgtcaactatgatgcttactactggagttggatccggcagcccccagggagtccactggagtggattgggtatgcccatcacagtgggagcaccaactacaacccctccctcaggagtcgagtcaccatttcagttgacccgtcgaagaataacttctccctgaggctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacttcgaaggatggttccagtttcgacctactactaccacagtttggacgtctggggccaaagggaccacggtcaccgtcttctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +13808 JY8QFUQ01CK0BJ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKKSIIIRGLI#YNFDYW out-of-frame + ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaagcattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13809 JY8QFUQ01A0EF3 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13810 JY8QFUQ01CSWAL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13811 JY8QFUQ01CQI4A productive Homsap IGHV3-9*01 F 990 95.39 207/217 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CAKEGNLGYFDDW in-frame + ctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtggatctcaggtattagctggaatagtggtagtatagggtatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13812 JY8QFUQ01AWL6G productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13813 JY8QFUQ01A5YFY productive (see comment) Homsap IGHV3-23*03 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) ctctggattcccctttagcaactatgacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13814 JY8QFUQ01B1VIH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtaattactGggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13815 JY8QFUQ01A8A7H productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacatactGggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13816 JY8QFUQ01DFQI1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13817 JY8QFUQ01BRQXE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag +13818 JY8QFUQ01DGMP9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13819 JY8QFUQ01DLVME productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13820 JY8QFUQ01AICL6 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 989 95.81 206/215 nt 94.42 203/215 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARYRGYQSYFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); tctctggtggctccaGtcagtCagttactactggagctggatccggcagcccccagggaagggactggagtGggattgggtatatctcttacagtgggggcaccaattacaatccctccctcaagagtcgagtcgccatatcaggagacacggccaagaaccagttctccctgaagctgaactctgcgaccgctgcggacacggccgtgtattactgtgcgcggtataggggttaccagagctactttgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13821 JY8QFUQ01DD8MX unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 689 79.82 174/218 nt Homsap IGHJ1*01 F (see comment) 107 67.31 35/52 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLGLNAVYAFDV## out-of-frame + stop codons Low V-REGION identity (79,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcgcttttggagattatgccatgaactgggtccgccaggccccagggaagggactggagtaggtctcaggtttgagcggtagaggcgtcagcaaatattatgcagactccgtgaggggccggttctccatttccagagacaactccgggagcgaggcagtccttcaaatgagcagcctgagagtcgaggacacggccacttactactgtgcgaggggcctagggcttaatgctgtctacgcatttgacgtctgggggacaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13822 JY8QFUQ01AXIAU productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13823 JY8QFUQ01BZ88U productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13824 JY8QFUQ01BE57F productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARTEYVSGWYIGGFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctatggtgggtcactcagttcttatttctggagctggatccgccagtccccagAgaaaaggactggagtggattggggaaatcaatcagagtggaaccaccaactacaacccgtctctcaggagtcgagtcaccatagcaatagacacgtccaagaaccagttctccctgaaggtgacctctgtgtccgccgcggacacggctgtctattactgtgcgaggaccgagtatgtcagtggctggtacatcggggggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtcgacggtgtcgtggcaactcag +13825 JY8QFUQ01AMVGJ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt 91.67 198/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 76 of V-REGION: 'GC' (2 nucleotides at position 133 to 134 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'C' (1 nucleotides at position 142 to 142 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggacGtccgtgcagggccggttGCgaccatcCtccagagacaattcgaagaaTcacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13826 JY8QFUQ01BTH1P No results +13827 JY8QFUQ01DJQDX productive Homsap IGHV3-7*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - ctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13828 JY8QFUQ01BO9N8 unproductive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD2-15*01 F 1 10 7 X 10.7.X [1.17.38.11] CATIVPSSVTALINDQGRFYFDHW# out-of-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactgggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtcgtcgtggaactcag +13829 JY8QFUQ01ASM4O productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13830 JY8QFUQ01BX0CV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt 85.32 186/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-20*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGLTTMTGNGLEHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggattcacccttcgcagatatggcatggcgtgggtccgccaggctccggggaaggGggctggagtgggtctcatcttctaacagtagtgatgaatccacatactatgcagactccgtgaagggccgcttcaccatttccagagaccattccaagaacacggtgtttttgcaaatgtacagcctgagagccgaagacacggccctctattactgtgcgagagggctaacaacaatgacagggaatggtcttgagcactggggccagggagccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13831 JY8QFUQ01ATUET productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13832 JY8QFUQ01ALDNJ unknown (see comment) Homsap IGHV1-58*01 F, or Homsap IGHV1-58*02 F or Homsap IGHV3-11*01 F or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F 50 100.0 10/10 nt 2 X X 2.X.X [1.X.X.X] null + No rearrangement found tctggattca +13833 JY8QFUQ01BJBC7 productive (see comment) Homsap IGHV3-11*01 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 14 8.8.14 [1.17.38.11] CTRDDRSVRGVTSDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 212 to 212 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgaccacttcatgagttggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggcagtggtagtataatatattacgcagactctgtgaggggccgattcaccatctccagggacaacgccaagaattccctctatctgcaaatggacagcctgagagacgaggacacggccgtgtatTttttgtacgagagatgatcgctcggttcggggagtcacctcagactactggggccagggaaccctggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13834 JY8QFUQ01AIZD8 No results +13835 JY8QFUQ01CNQ50 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 956 92.76 205/221 nt 91.86 203/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 7 10 10 7.10.10 [1.17.38.11] CTHLREEMSYEW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) tctggagtcaattcagaaacgcctggatgaattgggtccgccaggctccagggaAaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13836 JY8QFUQ01BNDM6 No results +13837 JY8QFUQ01DIKDT productive Homsap IGHV4-61*02 F 974 93.67 207/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSAPWNDHW in-frame + tctctggtggctccatcagcagcggttattactactggagctggatccggcagcccgccggggagggactggagtgggttgggcgtatctctgccagtggggacaccaactacaacccctccctcaagagtcgagtcaccatatcagtgaacacgtccaagaaccagttctccttgaggctgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagacaaggggacagtagtgctccctggaatgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13838 JY8QFUQ01B3HMA productive (see comment) Homsap IGHV4-61*02 F 883 89.5 196/219 nt 87.67 192/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.16.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctccggtggctccatcagtactggttattactactGggagctggatccggcagtccgccgggaagggactgaatggattgggcgcatgtctgccagaggggacagcaactacaAacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtaCtttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13839 JY8QFUQ01CPJVI productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13840 JY8QFUQ01BQY9M unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGV*QWL##DFDCW out-of-frame - stop codons cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13841 JY8QFUQ01AVBCS productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'GA' (2 nucleotides at position 23 to 24 in the user submitted sequence), (cause frameshift); tctctggattcaccgtcaatagGAaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13842 JY8QFUQ01CZ4DS unproductive (see comment) Homsap IGHV3-30*01 F 1085 100.0 218/218 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD3-10*02 F 2 8 8 X 8.8.X [1.17.38.11] CARDAQC*##YYYYGMDVW out-of-frame + stop codons cctctggattcaccttcagtagctatgctatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcatatgatggaagtaataaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgagagatgcccaatgttaggcactactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca +13843 JY8QFUQ01BHG5A unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-2*02 F 1 8 8 X 8.8.X [1.17.38.11] CVRVPTQWFPPSTLTLTS# out-of-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagttcctatagcatgagctgggtccgccaggctccggggaagggcctggaatgggtctctgctatcagtggcagcgatgatcgcacatcttatgttgactccgtgaagggccgcttcaccatctccagagacacttccaggaatacactgtttctgcagatgaacagcctgagcgccgaagatacggccacatacttttgtgtgagagtccccactcagtggtttccaccttccacactcactttgacatctgggccagggaaccgtggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +13844 JY8QFUQ01BZXCM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD6-25*01 F 1 8 8 22 8.8.22 [1.17.38.11] CARYQGDTSGYQDVFYAHYGMDVW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacttttaggggctactggatgcactgggtccgtcaggttccaggtaaggcgccggagtggctcgcacgtctgaatactgatggagatagtacaagttatgcggactccgtgaagggccgcttcaccatctccagagacaacgccaggagcacattgttcctgcaaatgagcagtctgagagtcgaagacacggccatttattactgtgcacggtatcagggcgataccagtggctaccaggacgttttctacgcccactacggtatggacgtctggggccaagggacctcggtcaccgtctattcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +13845 JY8QFUQ01BB6OG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-3*01 F 3 8 8 8 8.8.8 [1.17.38.11] CAKDMAFMEG in-frame + cctctggattcacctttagcgactatgccatgagctgggtccgacaggctccagggaagggcctggagtggctctcaagtattagtggtcgcggtttaagcacctactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacaccttgcatttgcaaatgagcagtctgagagccgacgacacggccatatattattgtgcaaaagatatggcttttatggaggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcccagggctnttcccc +13846 JY8QFUQ01CJZKY productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 738 82.49 179/217 nt 82.03 178/217 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); ctctggattcccctttagtgtgtactggatgtactgggtccgccAaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagagcttcttccccca +13847 JY8QFUQ01B4L9U unproductive Homsap IGHV3-7*03 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-11*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARDRYSSDSSYYMPNWLD#PG out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggGggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgaccccctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +13848 JY8QFUQ01DWBVC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 937 92.24 202/219 nt 91.78 201/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [2.17.38.11] CAKGYSSGWYDFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtagAttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13849 JY8QFUQ01CWXW5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13850 JY8QFUQ01BFTMS unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*04 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*03 F or Homsap IGHV3-66*04 F (see comment) 269 72.64 77/106 nt 8 7 X 8.7.X [1.17.1.X] null - No rearrangement found Low V-REGION identity (72,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggcttcaccgtcaataacaactacatgggctgggtccgccaggctccagggaaggggctggagtgggtcatcgcctgcctggtccagggcttcttccccca +13851 JY8QFUQ01AX32U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 761 83.49 182/218 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-1*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKSRRDWNDEGDVYDVW in-frame + Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gctctggattcatctttagagagtttgccatgacatgggtccgccaggctccagggaaggggctggagtgggtctcatttattgatcatagtgggaatgtcaaacgctacgcagacaccgtgaagggccggttcagtatatccagagacaactccaggaacatgttctatctagaagtgaacagcctgagagccgaggacacggccgtatattattgtgcgaaatcccgtcgagactggaacgacgagggtgatgtttatgatgtctggggccgagggacaatggtcaccgtctcttcagcatcccctgaccagccccaaggtcttcccgctgagcctcctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13852 JY8QFUQ01CVOKK productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 771 83.64 184/220 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFESW in-frame + Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ttccggtgactccatcaccagtactaattattactggggctgggtccgccagtccccagggaagggtctggagtggattggaagtgtctattatcgggggacccagtacctcaacccgtctctccacaatcaagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtcttttggagtgataattgttaactactttgagtcctggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13853 JY8QFUQ01B0KK3 productive Homsap IGHV3-7*01 F 973 94.06 206/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARTSSREITDYW in-frame - gcctctggattcacctttggtagctattggatgcgtcgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13854 JY8QFUQ01A6JRT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - gcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13855 JY8QFUQ01AJTT0 No results +13856 JY8QFUQ01B1QWY productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARFSGSYKSAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); gttctggatacatctttaccgactattggatcggctgggtgcgccagacggccgggaAaaggcctggagtggatgggaatcatctatcctggtgactctgacaccagttatggcccgtccttccaaggccaggtcaccatttcagccgaccagtccatcaccaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagattcagtgggagttacaaatcggcttttgatatctggggccgagggacaatggtctccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13857 JY8QFUQ01C1F3C No results +13858 JY8QFUQ01C6SW6 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 710 91.12 154/169 nt 8 7 X 8.7.X [1.17.22.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01C6SW6 ; 8 AA in Homsap_IGHV3-11*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatct +13859 JY8QFUQ01CVNUO No results +13860 JY8QFUQ01BF6AT unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 962 94.42 203/215 nt 93.49 201/215 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 7 8 17 7.8.17 [1.17.38.11] CA*KKHYNSGTYLYNFDYW in-frame - stop codons in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 27 in the user submitted sequence), (cause frameshift) tctggattcacctttagcaactttgcatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagAcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgtaaaaaaaacattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13861 JY8QFUQ01B8SWC productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13862 JY8QFUQ01AXWGT productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13863 JY8QFUQ01CP8N2 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [2.17.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); gtctatggtgggtccttcagtacttactactggacatGggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13864 JY8QFUQ01AHGB3 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 389 75.54 105/139 nt 8 8 X 8.8.X [1.17.11.X] null - No rearrangement found Low V-REGION identity (75,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13865 JY8QFUQ01BW7CO No results +13866 JY8QFUQ01BKMBL No results +13867 JY8QFUQ01AEL9L No results +13868 JY8QFUQ01AYXP4 productive (see comment) Homsap IGHV4-61*02 F 974 93.67 207/221 nt 92.76 205/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'G' (1 nucleotides at position 194 to 194 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccCttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtaaGcccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13869 JY8QFUQ01CVPXO No results +13870 JY8QFUQ01BGYJV productive (see comment) Homsap IGHV4-61*02 F 816 85.91 189/220 nt 85.45 188/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 10 7 18 10.7.18 [1.16.38.11] CAREDYYGSGSYGRAWFDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 83 in the user submitted sequence), (cause frameshift) tctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggattggcgcttctacagtcgtgggggtgtcgactacaacccctccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagaggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13871 JY8QFUQ01CQHUH productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13872 JY8QFUQ01C8UIH productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactc +13873 JY8QFUQ01B9O1F productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARAKLAGDGANWYFDLW in-frame - cctctggattcacccttagtagttattggatgaactgggtccgccaggttccagggaaggggctggagtgggtggccaacatacaccaagatggaagtgagacatattatgtggactctgtgaagggccgattcaccgtctccagagacaacgcgaggaactcactgtatctgcagatgaacaacttgaaagtcgatgacgcggctgtgtattactgtgcgagagcgaagttagcaggagatggtgcaaactggtacttcgatctctggggccgtggcactctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13874 JY8QFUQ01BP08J productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + cctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +13875 JY8QFUQ01BYKXO unproductive (see comment) Homsap IGHV3-9*01 F 792 85.25 185/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 79 62.0 31/50 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CGRIAKPGLGALDL## out-of-frame + stop codons cgttggattcacttttaatgaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctggggcccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttcccccaa +13876 JY8QFUQ01BRLSG productive (see comment) Homsap IGHV1-2*02 F 939 93.46 200/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 82 to 87 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13877 JY8QFUQ01ADDDA productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt 95.81 206/215 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARADNYDSLGLKFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtaactacCtggaactggatccggcagcccccagggaagggactggagtggattgggtatatctatcacagtgggagcaccagctacaacccctccctcaggagtcgagtcaccatatcattagacacgtccaagaaccagttctccctgaaactgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggcggataattatgatagtcttgggctgaagttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13878 JY8QFUQ01CYDQV productive Homsap IGHV3-48*03 F 850 88.43 191/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + tctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +13879 JY8QFUQ01BJ3YM unproductive (see comment) Homsap IGHV4-4*07 F (see comment) 692 80.47 173/215 nt 79.53 171/215 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-16*01 F 2 8 7 X 8.7.X [1.17.38.11] CARERGLSIGGAREF*LL# out-of-frame + stop codons Low V-REGION identity (80,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'ACCGAT' (6 nucleotides at position 18 to 23 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'GATGGATACACCAAGAATGATCCTTCCCTCAGGAGTCGA' (39 nucleotides at position 102 to 140 in the user submitted sequence), (do not cause frameshift); tctctggtggcgccatcACCGATactgactccttctggagctggattcggcagcccgccgggagcggtctggagtggatcggacgtgtttataatagtgggGATGGATACACCAAGAATGATCCTTCCCTCAGGAGTCGAatcaccaactacaatccttccctcaggggtcgaatctccatgtcagtggacacgtccaagaatcagtttctcttgaccttgaaatctgtaatcgccgaagacacagccgtctattattgtgcgagagaacgtggtctttcgattggcggagcgagagaattttgactcctggggcccagggaaccctggtcaccgtctcctcggcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct +13880 JY8QFUQ01DEX6Z productive (see comment) Homsap IGHV4-61*02 F 873 89.4 194/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [0.16.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift) ccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactgaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtaCtttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13881 JY8QFUQ01A2AEH productive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGSSGFNDAYFDNW in-frame + ctccggattcacctttaacacttattggatgaactgggtccgccaggctccagggaagggactggagtgggtggccaacataaaccaagatgggagcaggagacactatgtggactctgtgatgggccgattcaccatctccagagacaacaccaaggactcactgtatctgcaaatggacagcgtgagagccgaagacacggctgtctattactgtgcgaggggatctagtggattcaacgacgcctattttgacaactggggccagggaaccctggccacagtatcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggtcttcttcccccaag +13882 JY8QFUQ01B9TMK productive Homsap IGHV4-61*02 F 853 86.94 193/222 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD5-24*01 ORF 1 10 7 14 10.7.14 [2.17.38.11] CARGMATIKTVRFDPW in-frame - gtctctggtggctccatgaggagtggaattaattcctggacatggatccggcagcccgccgggaagggactggagtggattgggcgtatctatatcaatggagacaccaactacaatccctccctcaagagtcgggccagcatatcaatggacacgtccaagaaccagttctccctgcacttgacctctgtgaccgccgcagattcggccgtctattattgcgcgagagggatggccacaataaaaacggtccgattcgacccctggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13883 JY8QFUQ01CLUK6 unproductive Homsap IGHV3-48*01 F (see comment) 752 82.57 180/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDPREGA#FFDYW out-of-frame - Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggggttcagtcttaatacatatagtatgaattgggtccgccagattccagggaaggggctggagtgggtagggtacattagtagtactgggaataccatatattacgcagactctgtgaggggccgattcaccatctcccgcgacattgccgaaaattcactgtatctgcaaatgaatagcctgacacccgacgacacggctgtctattactgcgcgagagatccccgagagggggcaccttctttgactactggggccggggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13884 JY8QFUQ01CC9JY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD2-15*01 F 2 8 8 21 8.8.21 [1.17.38.11] CAKTGGQCSGGNCYLHYYGMDVW in-frame + ctctaaattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcacaggtattagtggtggtggtgaaaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagagcatgttgtatctgcaaatgaacagcctgagagccgaagacacggccgtattttactgtgcgaaaactggcggtcaatgcagtggtggtaactgctatttgcactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +13885 JY8QFUQ01B3MK5 productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [0.17.38.11] CATDRCTGGTCCPHYW in-frame + tggatacactttcaccagttattatatacactgggtgcgacaggcccctggacaggggcttgagtggatgggagttgtcaaccctggtgctgaatacacactctacgcacagaagttccagggcagactcaccttgaccagggacacgtccacgagcacagtctacatggagttgagtagcctgagatctgaggacacggccctgtattactgtgcgacagataggtgtactggtggtacctgctgtccacattactggggccagggaaccctgatcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13886 JY8QFUQ01CQD9H productive (see comment) Homsap IGHV4-59*03 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [2.17.38.11] CARGHFDSSGYSNPLDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 91 to 96 in the user submitted sequence), (do not cause frameshift); gtctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13887 JY8QFUQ01CIMH5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13888 JY8QFUQ01COXUM No results +13889 JY8QFUQ01B55T7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-48*03 F or Homsap IGHV3-69-1*02 P (see comment) 429 84.3 102/121 nt Homsap IGHJ6*02 F (see comment) 94 61.29 38/62 nt Homsap IGHD6-6*01 F 2 X 2 17 X.2.17 [X.X.38.11] CVRDLAARPPYYYYGMDVW in-frame + Low V-REGION identity (84,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcaccttcaactcagtgaagggccgattcaccatctccagagacgactccaagaactcactgtttctgcagatgaacagcctcagagccgaggacacggctgtttattattgtgtgagggatttggcggctcgtcccccttattattactacggtatggacgtctggggccaggggccacggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13890 JY8QFUQ01A3KZK unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 833 87.16 190/218 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRGTREWSGIDY## out-of-frame + cctctggattcattttcagtaactactggatgcactgggtccgccaagctccagggaaggggctgctctgggtctcagtcattaatagtgacggcagtgaaattcactacgcggactccgtgaggggccgattcaccatctcccgagacaacgccaagaacacgctgtatttgcaaatggacaatctcagaggcgacgacacggctctatattattgtgtaagagggacaagggaatggagcgggattgactactggggtcaggggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +13891 JY8QFUQ01BYZK6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13892 JY8QFUQ01BI7JX productive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtCgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13893 JY8QFUQ01B8LS6 unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*03 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARDELPWDTIEYY#LDYW out-of-frame + ctctggattcaccttcagtacctattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcatatgatggaaaaaaaaggtattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtacctgcaaatggacagcctgaggcctgaagacacggctgtatattactgtgccagagatgagctcccttgggatacaatagagtactactttggactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13894 JY8QFUQ01A0XQ3 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDY## out-of-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggcccagggaaacctggtcaccgtctcctcagcctccacaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13895 JY8QFUQ01DJ02O productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13896 JY8QFUQ01CKFEF productive Homsap IGHV3-30*06 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVRVSGGDGVNW in-frame - tctggattcaccttcagtacctctggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatttcatatgatggaagtagtaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctgtttctacaaatgagcagcctgagacctgaggacgcggcgatgtattactgtgtgagagtttctggtggggatggagtcaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13897 JY8QFUQ01B5WCV No results +13898 JY8QFUQ01DANKY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 867 89.72 192/214 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVSDLAGQKGSW in-frame - aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13899 JY8QFUQ01COVBF unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ5*01 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CANEVGYCSGG# out-of-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) tctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtgggggggcccaggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13900 JY8QFUQ01B8CTC unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 108 53.33 72/135 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons cctctggattcagtttcagagactatgccatgagttgggtccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13901 JY8QFUQ01BFKFB No results +13902 JY8QFUQ01AL5M7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13903 JY8QFUQ01ADX4H No results +13904 JY8QFUQ01AYXAJ unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANYW# out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13905 JY8QFUQ01COIIV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + gtctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13906 JY8QFUQ01DGP1W productive (see comment) Homsap IGHV3-11*01 F 1004 95.87 209/218 nt 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARGYSYGCFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'GGAGGGACT' (9 nucleotides at position 90 to 98 in the user submitted sequence), (do not cause frameshift); cctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcaaacatcaatagtGGAGGGACTagtgggaggaccatatattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagaggatacagctatggctgctttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13907 JY8QFUQ01BA4OA productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +13908 JY8QFUQ01AXQRP No results +13909 JY8QFUQ01B4EWS unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13910 JY8QFUQ01CR219 unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 815 85.78 187/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagccaagggaccacggtcaccgtctcctcaacctccaccaaggggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13911 JY8QFUQ01BFG7N productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13912 JY8QFUQ01AUQ2H unknown (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 968 93.58 204/218 nt 9 7 X 9.7.X [1.17.38.X] null + No rearrangement found stop codons tctctggtgactccatcagcaatgatagttggtggagttgggtccgccagcccccagggaaggggctggagtggattggggaaatctatcatactgggagcaccaactacaacccgtccctcaagagtcgagtcaccatatcactcgacaagtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacgcggccgtctattactgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +13913 JY8QFUQ01BK8JB unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactanttccccgaaccggtgacggtgtcgtggaactc +13914 JY8QFUQ01DCEQ6 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1075 97.78 220/225 nt 97.33 219/225 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 3 8 10 X 8.10.X [2.17.38.11] CTTDGGISS#FDFW out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtGaacgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaaactgctggtgggacaacagactacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcaaagaacacgctgtatttgcaaatgaacagcctgaaaaccgaggacacagccgtgtattattgtaccacagatgggggcatctcgtcccctttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13915 JY8QFUQ01DMHHL productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagccCcgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13916 JY8QFUQ01DGJ39 No results +13917 JY8QFUQ01BM7CU No results +13918 JY8QFUQ01DBLIP unproductive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDY* in-frame + stop codons in FR3-IMGT at codon 74 of V-REGION: 'A' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); cctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtgggctctgtgatggAgccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactgaggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca +13919 JY8QFUQ01BTTDX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 933 91.36 201/220 nt 90.91 200/220 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 80 to 82 in the user submitted sequence), (do not cause frameshift); agcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13920 JY8QFUQ01C6ZSG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13921 JY8QFUQ01BEO23 productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13922 JY8QFUQ01DM9SV productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1011 97.2 208/214 nt 96.26 206/214 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [0.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); gggtttcagcttcaggagctctggcatgaactgggtccgccaggctccagggaaGggggctggagtgggtctcatccaAttagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13923 JY8QFUQ01AIFVT No results +13924 JY8QFUQ01C4KPI unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 821 85.97 190/221 nt 85.52 189/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKGTRL*RLVYI#DSW out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); ggccgtctggattcattttagccaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagCcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaagggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13925 JY8QFUQ01DQU8I productive (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P (see comment) 746 83.26 179/215 nt 82.79 178/215 nt Homsap IGHJ6*02 F (see comment) 211 82.26 51/62 nt Homsap IGHD6-6*01 F 1 8 8 21 8.8.21 [1.17.38.11] CAKDLGYSISSGASTHYYGMGVW in-frame - Potentially, because of detected insertion/deletion however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01DQU8I ; 7 AA in Homsap_IGHV3-69-1*01), and low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); cctctggattcgcttttggtgactatgccatgaactgggtccgccaggctccagggaaggggcCtggaatgggtctcatttgtcaccactactggcagttccacatattatgcagactccgtgaagggccgattcaccgtttccagagacgacgccaagaatctactgtatcttcagatgaccggcctgagagacggggacacggctacatattactgtgcgaaagacttggggtacagcatctcgtcgggggcctccacgcactactacggaatgggcgtctggggccaagggacaacggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13926 JY8QFUQ01BRRCI productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13927 JY8QFUQ01AW9QR productive (see comment) Homsap IGHV4-4*07 F, or Homsap IGHV4-59*10 F 791 85.58 184/215 nt 84.65 182/215 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-22*01 F 2 10 7 21 10.7.21 [1.17.38.11] CARDVYDDGGYYGPYYYYGMAVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); tctccggtgAgccccatggccaataataatttctattggagctggattcggcagcccgccgggaaggGggctggagtggcttgggcgtgtgtatgtcagtgggaccaccaactacaaccccgccctcgagagtcgaatcaccatttcaatagatcggtccaagaaccagttctcgctgaacttgacctcagtgaccgccgctgacacggccatttattactgtgcgagggatgtttatgatgatggcggttattacggtccttattattactatggaatggccgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13928 JY8QFUQ01AGCW5 No results +13929 JY8QFUQ01A3A1C productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13930 JY8QFUQ01A9TVY unproductive Homsap IGHV3-7*01 F 964 93.61 205/219 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [2.17.38.11] CARVGYGYRGIYFFDY## out-of-frame + gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccaatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +13931 JY8QFUQ01BTRLU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - agcctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13932 JY8QFUQ01DIY9J productive Homsap IGHV3-66*02 F 894 91.12 195/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccatcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaaggactacttccccgaaccggtgacggtgtcgtggaact +13933 JY8QFUQ01DP6FF productive (see comment) Homsap IGHV3-11*01 F 878 89.45 195/218 nt 88.53 193/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVDIRLGDWFFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagtgaccactacatgagctggGgtccgccaggctccggggGAaggggtctggagtggatctcatacatcagtacaagtggtaatatggtttattacgcggactctgtgaagggccgattcaccgtctccagggacaacgccaagaactcactgtatctgcaaatgaacggcctcagagtcgaggacacggccgtctattactgtgtcgacataagactgggtgattggttcttcgatctctggggccgtggcaccctggtaactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13934 JY8QFUQ01CMM9U unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARKRVPGGNFLM#DYW out-of-frame + cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggaactttttgatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccttgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +13935 JY8QFUQ01ASGP6 unproductive (see comment) Homsap IGHV3-48*03 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDLNWSFDS# out-of-frame + stop codons in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); cctctggattcacctttactagttaCagttttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctgtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13936 JY8QFUQ01C7BM8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 438 85.12 103/121 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 X 2 22 X.2.22 [X.X.38.11] CVRDRLYDSSGYDFGELGDYSDHW in-frame + ctctggattcgccttcaactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagggccgaagacacggctgtatatttttgtgtgagagatcgtctctatgatagtagtggttatgactttggggaattgggggactattcagaccactggggccagggaacccaggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13937 JY8QFUQ01B4I6V No results +13938 JY8QFUQ01AHAA1 productive Homsap IGHV3-48*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKVGSMNIEASPPDDW in-frame - ctctggattcagcttcagttcctatagcatgagctgggtccgccaggctccggggaaggggctggagtgggtctcatatattagtagtagtggtaggaccatctactacgctgactccgtgaagggccgattcaccatgtccagagacaatgccaagaattcactgtatctacaaatgaacagcctgagagccgaggacacggccgtctattactgtgcgaaagttggcagcatgaatatcgaggcgagccctcctgacgactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacatggtcatcgcctgcctggtccagggcttcttccccca +13939 JY8QFUQ01BBTLX unproductive Homsap IGHV3-48*02 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.16.38.11] CARGQNGYKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) cctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccaggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13940 JY8QFUQ01A9C87 productive Homsap IGHV4-39*02 F 952 91.89 204/222 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [2.17.38.11] CARRYSWNYERFDPW in-frame - gtctctggtgactccatcagtactaataattactactgggcctggatccgccagcccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13941 JY8QFUQ01AOGS5 productive (see comment) Homsap IGHV1-8*01 F 907 92.02 196/213 nt 91.55 195/213 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [0.16.38.11] CAREGLLGSLGSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) aggatacaccttcatcagttatgatatcaattgggtgcgacaggccactggacaaggcttgagtggatgggatggatgaaccctaacagcggtaacacagggtttgcacagaggttccagggcagagtaaccatgaccaggaacatctccataaacacggcctacatggagctgaccaacctgacatctgatgacacggccgtatattattgtgcgagagaaggtctattgggcagcctaggatcttggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13942 JY8QFUQ01B7V6O unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 353 86.17 81/94 nt 8 5 X 8.5.X [1.17.X.X] null - No rearrangement found ctctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc +13943 JY8QFUQ01ANXAZ productive (see comment) Homsap IGHV1-3*01 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 71 of V-REGION: 'A' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagAttgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +13944 JY8QFUQ01AVXVQ productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*02 F 1 8 8 12 8.8.12 [1.17.38.11] CGRPGRWDLSLDYW in-frame - cctctggattcatctttagtgactattacatgacctgggtccgccagagtccagggaaggggctggagtgggtggccaacataaaccaagatggaactgagacatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaaaaagtccctgtatctgcaaatgcacagcctgagaaccgacgacgcggctttatattactgtgggagaccagggagatgggatttatctcttgactattggggccagggaaccgtggtcaccgtctccttagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13945 JY8QFUQ01CJ5SE unproductive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPPWCWG#FDNW out-of-frame + stop codons cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactccccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccgatcggtcttccccctggcgccctgctcccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13946 JY8QFUQ01DON2B No results +13947 JY8QFUQ01AKVLH productive (see comment) Homsap IGHV3-23*05 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13948 JY8QFUQ01AM13O No results +13949 JY8QFUQ01C4USB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13950 JY8QFUQ01CFG8N productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 909 91.24 198/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKVSGNSRTYWYLDIW in-frame + ttctggatacaactttcccagatattggatcgcctgggtgcgccagattcccgggagaggcctggagtgggtggggatgatctatcctggtgactctgagaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacgcgtccatgaacaccgcctacctgcagtggagcagcctgaaggcctccgacaccgccatatacttctgtgcgaaggtctctggtaactctcgaacctactggtacctcgatatctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +13951 JY8QFUQ01BLE7A productive (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 285 82.35 70/85 nt 81.18 69/85 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); ctctggattcagagacaatgccaggaactccctctacttgcAaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcatgcctggtccagggcttcttccccca +13952 JY8QFUQ01CUDCX No results +13953 JY8QFUQ01DG6GC productive Homsap IGHV3-30*15 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame + ctctggattcacctttagtagatattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttatatcatacgatggaagtagaagaatctacgcagactccgtgaagggccgattcaccatctccagagacacttccaagaacacggtgtatctgcaaatgagtagcctgagacctgaggacacggctgtgtattactgtgcgagagatgagctgccttgggatacaatagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +13954 JY8QFUQ01BAPLA productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 885 90.65 194/214 nt 89.25 191/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKINNDFGDYDWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); ctctggtgtctccatcagtagttcctactggagttggatccggcagCcccccagggaagggcctggagtggattggttatgtctattatactggGgggcaccgactccaaccCcctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaatcaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +13955 JY8QFUQ01CP3WA productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca +13956 JY8QFUQ01AJ6F3 productive Homsap IGHV4-61*01 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame + tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggccccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13957 JY8QFUQ01CNYIB productive (see comment) Homsap IGHV3-48*02 F (see comment) 743 82.11 179/218 nt 81.65 178/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaaggggActggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +13958 JY8QFUQ01A1MR0 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13959 JY8QFUQ01DTU0D unknown (see comment) Homsap IGHV4-4*07 F (see comment) 525 73.04 149/204 nt 72.55 148/204 nt 10 6 X 10.6.X [1.17.35.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01DTU0D ; 8 AA in Homsap_IGHV4-4*07), and low V-REGION identity (73,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 102 in the user submitted sequence), (do not cause frameshift) tctctggtggcctcatcagaggcggtggtttctactggacctggctccggcagtccgccgggaagggcctggagtggatcggacgtatttatgacagtggcagtgactacaatccttctctcaagagtcgagtcaccatgtcagtagacacgtccaagagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13960 JY8QFUQ01CABRX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcactccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgaccggtgtcgtggaactcag +13961 JY8QFUQ01CNER9 unproductive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 849 88.79 190/214 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [0.17.38.11] CARGGGFQ*TSGEG#YYNGLDVW out-of-frame + stop codons tggatacaccttcagcagttattatatacactgggtgcgacaggcccccggacaggggcttgagtggatggcaatgatcaacccaagtggtggtagtaccacgtacgcacagaagttccagggcagactcatcgtgaccagggacacgtccacgagtagtgtctacatggacctgagtagcctgagatctgaggacacgggcgtctatttctgtgcgagaggggggggcttccagtaaacgtcaggtgaagggactactacaacggtctggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13962 JY8QFUQ01B5KT0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [0.17.38.11] CAKVVWSLWYFDLW in-frame - tacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13963 JY8QFUQ01CUMC5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1041 97.27 214/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame + ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13964 JY8QFUQ01A69S0 productive Homsap IGHV3-48*01 F 1075 99.54 215/216 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASIFGVVPLGNYYYGMDVW in-frame - tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13965 JY8QFUQ01BA6HX unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CA*KKHYNSGTYLYNFDYW in-frame - stop codons in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); gtcctctggattcacctttagcGaactttgccatgacctgggtccgccaggctccagggagggggActggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggatagcctgagagccgaggacacggccgtatattactgtgcgtaaaaaaaacattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +13966 JY8QFUQ01CCDCV productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +13967 JY8QFUQ01DRROF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKASPKWEFLRTTFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGcctttcgcagctatgccatgacctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtgctggtagcacattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgacgacacggccatctacttctgtgcgaaggcgtcgccgaagtgggagtttctacgaaccacctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13968 JY8QFUQ01CVB6S unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CARQYGSSSYVDF## out-of-frame - tctggatacatctttaccagctattggatcggctgggcgcgccagatgcccgggaaaggcctagagtggatggggatcatctatcctcctgactccgatacaagatacagaccggccttccaaggccaggtcaccatctcagtcgacaagtccaccagtaccgcctacctgcagtggagcagcctgaaggcctcggacagcgccatgtattactgtgcgagacaatatggttcgagcagttatgttgacttttggggccaggggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13969 JY8QFUQ01B4F5F No results +13970 JY8QFUQ01A92WW No results +13971 JY8QFUQ01AXELT unproductive Homsap IGHV3-7*01 F 991 94.98 208/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CARDPYNGGGYGAFDI## out-of-frame - gcctctggattcacctttagtaataattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacatcaagcaagatggaagtgagaaagtctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgcaaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagacccctataatggtggtggttatggtgcttttgatatctgggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaagggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13972 JY8QFUQ01CR0ZE unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13973 JY8QFUQ01AKWSG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13974 JY8QFUQ01AIRJC productive Homsap IGHV4-4*07 F 590 87.1 135/155 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 X 7 15 X.7.15 [X.6.38.11] CARQRGGGDRQWAFENW in-frame - gactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13975 JY8QFUQ01BSOV2 No results +13976 JY8QFUQ01B2ACS productive Homsap IGHV3-11*01 F 1008 96.31 209/217 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD2-2*01 F 2 8 8 12 8.8.12 [1.17.38.11] CAVDCTSISCNGDW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctgggttcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggctttcatatattagtagtgctggtagtaccatatactacgcagactctgtgaggggccgattcaccatctccagggacaacaccaagaactcactgtatctgcaaatgaacagcctgagggccgaggacacggccgtgtattactgtgcggtagattgtactagtatcagctgcaacggagactggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13977 JY8QFUQ01A7Z8B productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 956 92.76 205/221 nt 91.86 203/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 7 10 10 7.10.10 [1.17.38.11] CTHLREEMSYEW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) tctggagtcaattcagaaacgcctggatgaattgggtccgccaggctccagggaAaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13978 JY8QFUQ01BX22A No results +13979 JY8QFUQ01C5TP7 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1007 94.64 212/224 nt 94.2 211/224 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); cctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaaGtatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13980 JY8QFUQ01COIZ4 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARPGVGASSFIDFW in-frame + ttctggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +13981 JY8QFUQ01C359E productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 6 10 9.6.10 [2.17.38.11] CASHGGKYFPQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) gtctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcccccagggaagGgggctggagtggattggacaaatccatcatgtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +13982 JY8QFUQ01BOZ0H productive Homsap IGHV3-30*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDELPWDTIEYYFDYW in-frame + ctctggattcaccttcaatacctattctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13983 JY8QFUQ01AM51E productive (see comment) Homsap IGHV3-7*01 F 918 91.71 199/217 nt 90.78 197/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [2.16.38.11] CARAKLAGDGANWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) gcctctggattcacccttagtagttattggatgaactgggtccgccagttccagggaaggggctgagtgggtggccaacatacaccaagatggaagtgagacatattatgtggactctgtgaagggccgattcaccgtctccagagacaacgcgaggaactcactgtatctgcagatgaacaacttgaaagtcgatgacgcggctgtgtattactgtgcgagagcgaagttagcaggagatggtgcaaactggtacttcgatctctggggccgtggcactctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13984 JY8QFUQ01BA6GM productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +13985 JY8QFUQ01A5HNY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgaccggtgtcgtggaactc +13986 JY8QFUQ01B6E5B productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13987 JY8QFUQ01BOQCN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13988 JY8QFUQ01BFRFT productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [2.17.38.11] CAKDLFQVSTTYFDYW in-frame - gcctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13989 JY8QFUQ01BJG2Y productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13990 JY8QFUQ01CP2YJ productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-25*01 F 1 8 8 10 8.8.10 [1.17.37.11] CTKLYRSYYEYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 105 in the user submitted sequence), (cause frameshift) cctctggattcagttttagtgactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaatatgaatcaagatggaagtgagaaaactatgtggactctgtgaagggtcgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatgtattattgtacgaaattgtatcggagctactacgaatactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca +13991 JY8QFUQ01A9K2Q unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13992 JY8QFUQ01BN3QI productive (see comment) Homsap IGHV3-48*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggGggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtagaact +13993 JY8QFUQ01BT7V8 productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVKGAGTTVNWFDIW in-frame + ctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatggaaacgtggtcatcgcctgcctggtccagggcttcttcccccca +13994 JY8QFUQ01BGFG8 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 823 87.04 188/216 nt 86.57 187/216 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.16.38.11] CARGFSAWGQDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaagggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13995 JY8QFUQ01BPANL No results +13996 JY8QFUQ01AJRNU productive Homsap IGHV4-61*02 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-8*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARGYCSNAVCYQIMNW in-frame - tctctggtggctccatcagcagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggccgtgtattactgtgcgagaggatattgttctaatgctgtatgctatcaaatcatgaactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13997 JY8QFUQ01DWTPQ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [2.17.38.11] CARGGLEPVDYW in-frame - ccctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +13998 JY8QFUQ01BLD8G productive Homsap IGHV3-48*02 F 986 94.95 207/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARPAGEGDPFFHYYSGLDVW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +13999 JY8QFUQ01A0O4F unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactGggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14000 JY8QFUQ01CKUI7 No results +14001 JY8QFUQ01BCFF4 No results +14002 JY8QFUQ01A1R7K productive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 826 87.79 187/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 7 8 12 7.8.12 [0.17.38.11] CARGPVSGWYGDFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) tggatacatcttcaaaactactatatattctgggtgcgacgggcccctggacaagggcttgagtggatgggttgggtcaaccctaacagtggtgccacacactatgcaccgaaatatcagggccgggtcaccatgaccagggacacgtcattcgccacagcctacatggatttgagcatgttgacatctgacgacacggccatgtattactgtgcgagaggccctgtcagtggttggtatggtgacttctggggccagggaaccctagtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14003 JY8QFUQ01ATOJH unproductive Homsap IGHV3-9*01 F 820 86.3 189/219 nt 85.84 188/219 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [2.17.38.11] CVKDRKSWWLQSVGC#FDIW out-of-frame - in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcgacgactatgtcatgcattgggtccggcaagttccagagaggggcctggagtgggtcgcaggcattaatggggaaagtaatagAttttggctctgtggactctgtaaagggccgattcaccatctccagagacaaggccaagaataccctgtatttgcaaatgaatagcctgagagttgaggacacggccttgtattattgtgtgaaagatagaaaaagctggtggctacaatctgttggatgcattttgatatctggggccaagggacaatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14004 JY8QFUQ01BZKLC No results +14005 JY8QFUQ01DSG9D No results +14006 JY8QFUQ01AYDQ1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 888 89.55 197/220 nt 89.09 196/220 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); aggctctgacttGcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14007 JY8QFUQ01C0A7I productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +14008 JY8QFUQ01A58UD productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14009 JY8QFUQ01AKWB3 No results +14010 JY8QFUQ01AKOZJ productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1017 96.77 210/217 nt 96.31 209/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 3 7 8 20 7.8.20 [1.17.38.11] CARLPYIVVLTNIISPTYFDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) tttctggatacagtttaccagttactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctgctgactctgataccagatacagcccgtccttccaaggccaggtcagcatctcagccgacaagtccatcgacaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgcggctgccatatattgtggtgctgactaatataatctccccaacctactttgacttctggggccagggaacccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14011 JY8QFUQ01AYR9G productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ6*02 F 157 72.58 45/62 nt Homsap IGHD1-14*01 ORF 2 8 8 16 8.8.16 [1.17.38.11] CARDRSVPQPKYYGMDVW in-frame + ctctggattcaccttcaataactataacatgaactgggtccgccaggctccagggaaggggctggagtggatctcatccattagtagtggtagtaatgacataaactacgcagactcagtgaggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggtcggtgccgcaaccaaagtactacggtatggacgtctggggccaagggaccacggtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14012 JY8QFUQ01DQ6LN No results +14013 JY8QFUQ01DKQ19 No results +14014 JY8QFUQ01CIFL3 productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame - ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14015 JY8QFUQ01CDVO9 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 724 81.48 176/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (81,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +14016 JY8QFUQ01CC912 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14017 JY8QFUQ01BPUAJ No results +14018 JY8QFUQ01A09OY productive Homsap IGHV3-11*01 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - gcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14019 JY8QFUQ01CAJM5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagttactggatgcactgggtccgccAaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14020 JY8QFUQ01BB7QU No results +14021 JY8QFUQ01A666E productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [2.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - gcctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14022 JY8QFUQ01A19SQ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +14023 JY8QFUQ01BTB07 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14024 JY8QFUQ01DI845 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CANEVGYCSGGG in-frame + cctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14025 JY8QFUQ01B3OBX productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 930 91.03 203/223 nt Homsap IGHJ4*03 F (see comment) 78 62.5 30/48 nt Homsap IGHD3-22*01 F 3 8 10 24 8.10.24 [1.17.38.11] CATDRPYYKKSLLADSGITTVWTFWG in-frame + Other possibilities: Homsap_IGHJ1*01 (shorter alignment but highest percentage of identity) ctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaaatcgctgctggccgactctggtattactacggtatggacgttttgggggcccaaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14026 JY8QFUQ01BX3CP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVKEDHDSGLRVLLEW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14027 JY8QFUQ01CBYEJ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14028 JY8QFUQ01AW6B3 productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccgatcggtcttccccctggcgccctggctcccaggagcacctccgagagccacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14029 JY8QFUQ01B2NJT No results +14030 JY8QFUQ01C49WA No results +14031 JY8QFUQ01CR6ST productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14032 JY8QFUQ01DMXLR productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 902 90.05 199/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); aggcctctggattcaCcctttggttattatggcatggactgggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14033 JY8QFUQ01A0TAV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactca +14034 JY8QFUQ01CYKY8 productive (see comment) Homsap IGHV3-7*01 F 987 94.55 208/220 nt 93.64 206/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); gacctctggaGttcacctttaGgtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14035 JY8QFUQ01APLYG No results +14036 JY8QFUQ01DJK44 productive Homsap IGHV1-18*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 3 8 8 15 8.8.15 [0.17.38.11] CARGTQVRGVIKRPDYW in-frame - tggctacacgtttacctactatggtatcaactgggtgcgacaggcccctggacaaaggcttgagtggctgggatggattagcccttacaacggacacacaaactctgcacagagcctccagggcagagtcaacttgaccacagacagatccacgagcacggcctacatggagctgacgagcctgatatctgacgacacggccgtgtattactgtgcgagaggaacgcaggttcggggtgtgatcaagagacctgactactggggccagggaacccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctcggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14037 JY8QFUQ01CGCMM No results +14038 JY8QFUQ01A9W4E productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 911 90.5 200/221 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-1*01 F 2 10 7 8 10.7.8 [1.17.38.11] CATVDRLTYW in-frame + tctctggtgtctccatgagcagtcttacttactactggggctggattcgccagccccccgggaagggcctggagtggattgggactctcttttatagtgggagcacctactacaatccgtccctcaggagtcgagtcaccatatccgctgactcgtccaagaaccagttctccctgaacctaaggtctgtgaccgccgcagacacggctgtctatttctgtgcgacggtggatcgactgacctactggggccggggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14039 JY8QFUQ01BKJ53 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 88 in the user submitted sequence), (cause frameshift) cctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +14040 JY8QFUQ01C4LWE productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14041 JY8QFUQ01DAYCB productive (see comment) Homsap IGHV3-48*01 F 1080 100.0 217/217 nt 99.54 216/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 94 of V-REGION: 'C' (1 nucleotides at position 185 to 185 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcCctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14042 JY8QFUQ01BJMYD productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F (see comment) 580 73.33 165/225 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*01 F 2 10 9 13 10.9.13 [1.17.38.11] CTRGSLTGTYPSDHW in-frame + Low V-REGION identity (73,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttcggagacgatatatctggagacagtgttacttggaactggatcaggcagtccccagggagggggcttgagtggctcgggcgtatctttcacaggtctgagtggcataccgactacttggcgtctgttagaggccgaatctccatggatgtcgacacgtccaagaaccacttcaccctgcagctccgctctctgactcccgacgacacggctacatatttctgtacaagaggctctctaactgggacatatccttctgaccactggggtctggggaccccagtgaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14043 JY8QFUQ01CTQ0O unproductive Homsap IGHV4-4*07 F 872 89.77 193/215 nt 88.84 191/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-24*01 ORF 3 9 7 X 9.7.X [1.17.38.11] CARDFWRFLQFSG#YW out-of-frame + in CDR1-IMGT at codon 36 of V-REGION: 'ATT' (3 nucleotides at position 25 to 27 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'T' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtgATTctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattTacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14044 JY8QFUQ01DF324 productive (see comment) Homsap IGHV4-61*02 F 844 86.94 193/222 nt 86.49 192/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 10 7 15 10.7.15 [2.17.38.11] CAREGDGYIYKRSFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'C' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); gtctctggtggctccgtcagtagtggttcttactactggagctggacccggcagcccgccgggCaagggactggagtggattgggcgtgtccacagcggtggcagttccgactacaacccgtccctcacgggtcgagccaccatcttagtggactcctccaagaatcagttctccctgaggctgacctctgtgacggccgcagacgcggccgagtattactgtgcgagagagggggatggctacatctacaagaggtcttttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14045 JY8QFUQ01COK70 productive Homsap IGHV3-48*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-16*02 F 2 8 8 8 8.8.8 [1.17.38.11] CARDVPYRNW in-frame + ctctggattcagcttcagtacctatagcatgaactgggtccgccagactccagggaaggggctggagtgggtttcatacattagtagtagtggtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctatttattactgtgcgagagatgtcccttatcgcaactggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14046 JY8QFUQ01ANH7Z productive (see comment) Homsap IGHV3-48*04 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaagggactggagtggggttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14047 JY8QFUQ01A9DBC productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1004 95.87 209/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +14048 JY8QFUQ01CH409 productive Homsap IGHV3-66*02 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame + ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +14049 JY8QFUQ01ATS4G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14050 JY8QFUQ01BU3FD unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 487 83.94 115/137 nt 83.21 114/137 nt 8 8 X 8.8.X [1.16.12.X] null + No rearrangement found Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactca +14051 JY8QFUQ01C05E8 unknown (see comment) Homsap IGHV3-23*02 F, or Homsap IGHV3-23*03 F (see comment) 222 65.0 78/120 nt 63.33 76/120 nt 7 8 X 7.8.X [1.16.6.X] null + No rearrangement found Low V-REGION identity (65,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggatacagtttaacagttatgccatgacttgggtccgccaggctccagggaagggctggagtgggtcccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +14052 JY8QFUQ01DJHPR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 815 86.24 188/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-16*02 F 3 8 8 23 8.8.23 [1.17.38.11] CARDRRVFFGQLITTKIYHYGMDVW in-frame - cctctggattcaacttcaattattatagcatgagttgggtccgccaggctccgggaaagggactggagtgggtttcatacattagtactagtagtagttacatgtattacacggactccgtgaagggccgcttcaccgtctccagagacaacgccaagaaatctctgtatctggaaatgaacagcctaagggacgaggacacggctgtctacttttgtgcgagagatcgacgagtgttctttggacaattaataaccaccaaaatctaccactacggcatggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14053 JY8QFUQ01CC9HI productive Homsap IGHV3-9*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKDRGSSSKYYFDYW in-frame - cctctggattcacctttgatgattatgtcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggggaagtgctcatatacactatgcggactctgtgaaggaccggttcaccatctccagagacaacgccatgaactccctttatttgcaaatggacagtctgagagctgacgactcggccttgtattactgtgtaaaagatcggggtagcagttccaagtattactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14054 JY8QFUQ01BS7HV unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 86 57.53 42/73 nt 8 X X 8.X.X [1.14.X.X] null - No rearrangement found cctctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14055 JY8QFUQ01BUOD5 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 883 89.5 196/219 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [2.17.38.11] CARDLRGSTMASD#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctccgactgtcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaaggggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc +14056 JY8QFUQ01AHQCJ No results +14057 JY8QFUQ01DU8GL No results +14058 JY8QFUQ01ATDFY productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +14059 JY8QFUQ01DR144 unproductive Homsap IGHV3-7*01 F 941 92.66 202/218 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CATSPFTVTTGKDAY## out-of-frame + tctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggcccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14060 JY8QFUQ01B9CJF productive (see comment) Homsap IGHV1-2*02 F 808 86.85 185/213 nt 86.38 184/213 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD3-16*02 F 2 8 7 15 8.7.15 [0.17.38.11] CARHFCDTNDVCDFDIW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 88 in the user submitted sequence), (cause frameshift) tggatacagcttcaccgacttttacattcattgggtgcgacaggaccctggacaagggcttgagtggatggggtggaccaaccctaaaatggtggcacgttcattacgctgaagtttcagggcagggtcactatgtccagggacacgtccatgaccacagtctatatggagatgagcaggctgagatctgacgacacggccatttattactgtgcgagacatttttgtgacaccaacgacgtctgtgattttgatatctggggccaggggacaaaggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +14061 JY8QFUQ01CZTSW No results +14062 JY8QFUQ01BI2BQ No results +14063 JY8QFUQ01AKY7R No results +14064 JY8QFUQ01C6USK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14065 JY8QFUQ01B7J8X No results +14066 JY8QFUQ01DDCM9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 879 89.09 196/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [2.17.38.11] CVREGAATGSFYYW in-frame - aacctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14067 JY8QFUQ01CQE5A productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 738 82.03 178/217 nt 81.57 177/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 8 13 8.8.13 [1.17.38.11] CVRGVRDGTGIIDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); ccatggattcctcttcagtggccactggatgcactgggtccgccaagctccagacaaggggctggcgtgggtctcaCgtcttaaccccggacgggagttttacgaactatccggactccatgaggggccgattcgccatctccagagacaacgccaagaacacagtgtatctgcaaattaacaatctgagacccgatgacacggccgtctattactgcgtaagaggcgtaagagacggaactggaatcatcgactactggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14068 JY8QFUQ01CD3K8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 797 85.32 186/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagtcgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14069 JY8QFUQ01BS1BC No results +14070 JY8QFUQ01BM6SP unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*08 F (see comment) 764 84.19 181/215 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 111 68.63 35/51 nt 8 7 X 8.7.X [1.17.38.11] CASVRPRRTVLRL (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggctcgctcacgggtttcaagtggggctggatccggcagcccccaggggagggactgcaatggattggacatatctctttcgttggggacaccagttatgacccttccctcaggagtcgagtcaccatttcagtcgacacgtccaagaaccagttctccctgaaactgaactctatgactcctgcggacacggccgtctattactgtgcgagcgtgcgtcctcggagaacggttcttcgacttctgggcctggaaccctggtcaacgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccagg +14071 JY8QFUQ01CXQ06 No results +14072 JY8QFUQ01BXEW2 No results +14073 JY8QFUQ01DMU46 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 568 73.06 160/219 nt 72.6 159/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (73,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctagattcaTcgtttagtagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactatcagtggtagtggtgataacacatactacgcagactccgtgaagggccggttcaccatctccagagacaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14074 JY8QFUQ01CRNW3 productive Homsap IGHV3-11*01 F 855 88.48 192/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDGDADYGDLPIPFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctgaattcagtttcactgaccaccacatgagctggatccgccgggctccagggaaggggctggagtgggtgtcatacattagtcctacaggtagtgccatattttacgcagactctgtgaaggcccgtttcaccatctctagggacaacgccaagaatttactatatctacaaatgaacagcctgagacccgaggacacggccatctattactgtgcgagagatggggacgcggactacggtgacttgcccatccctttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14075 JY8QFUQ01AOHFB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14076 JY8QFUQ01C1CU1 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDNYGDYW# out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14077 JY8QFUQ01ARFJE unknown (see comment) Homsap IGHV3-11*01 F (see comment) 707 80.28 175/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcaccttcagcgacaactacatgagctggatccgccaggctccagggaaggggctggattgggtttcatacattagtagtagtggtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcacttttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14078 JY8QFUQ01C6PCV productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14079 JY8QFUQ01CH9ZV No results +14080 JY8QFUQ01CI1BM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14081 JY8QFUQ01A607Q unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [0.17.38.11] CARDLIAAADNGGFG#NWFDPW out-of-frame - in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); tggatataccttcagcaattactatatgcactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcaaccctagtggtggtggcacaaAactacgcacggaagtttcaggacagagtcaccatgaccagggacacgtccacgaacacagtgtatatggagctgagcagcctcagatctgaggacacggccgtatattactgtgctcgagatcttatagcagcagctgataatggggggtttggggaactggttcgacccctggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14082 JY8QFUQ01C3WLI productive (see comment) Homsap IGHV3-7*01 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [0.17.38.11] CVRGRDGVNFGEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctgggttcatctttagtagacattggatggcctgggtccgccaggctccagGggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14083 JY8QFUQ01CF1C3 No results +14084 JY8QFUQ01DERB1 No results +14085 JY8QFUQ01AOJ8L productive (see comment) Homsap IGHV1-2*02 F 939 93.46 200/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 82 to 87 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14086 JY8QFUQ01DVOAK productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 947 92.31 204/221 nt 91.86 203/221 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARDQSLGMPEAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); cagcctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtAgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgcccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14087 JY8QFUQ01DKG5C unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 904 91.2 197/216 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14088 JY8QFUQ01A3ZFE productive Homsap IGHV3-7*01 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14089 JY8QFUQ01B91TW productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 7 8 15 7.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14090 JY8QFUQ01BYSF3 productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccagccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14091 JY8QFUQ01A4TFA productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggGggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14092 JY8QFUQ01COGK9 No results +14093 JY8QFUQ01CU3ZW productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagccgtccaccgaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14094 JY8QFUQ01CLSK8 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 878 89.45 195/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + cctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt +14095 JY8QFUQ01AUA9M No results +14096 JY8QFUQ01BKXS7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKESLVRGVISYYFDDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) cctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggtttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctggttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14097 JY8QFUQ01B8XQA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [1.17.38.11] CANACPPYNWN#YFYYYGMDVW out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); tctggattcaTcgttcagtagcGtatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctgccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14098 JY8QFUQ01DA9FW productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 959 93.58 204/218 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARLPNTIDSW in-frame + Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) cttctggatatagttttgccacctactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatgggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatttcagccgacaagtccctcagtatcgcctacctgcagtggagcagcctgcaggcctcggacaccgccatatattactgtgcgagactgcctaacactattgactcctggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14099 JY8QFUQ01AESJH productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 849 88.79 190/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 7 16 8.7.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame - ttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacagtacatttgcaaatggacagcctgagagccgaggacacggctgtatattactgtgccagagatgagctcccttgggatacaatagagtactactttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14100 JY8QFUQ01A086G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [1.17.38.11] CVRYDYSRLHRSNYFGPW in-frame - tctctggatttaccttcatcagttatggcatgagttgggtccgccagtttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14101 JY8QFUQ01BLH3L unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANYW# out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14102 JY8QFUQ01AD8K3 No results +14103 JY8QFUQ01BGG1W unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 101 95.45 21/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggattcaccttaagtga +14104 JY8QFUQ01ATP3O No results +14105 JY8QFUQ01B8RHG productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'CG' (2 nucleotides at position 91 to 92 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCGgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14106 JY8QFUQ01AIJVY productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 764 84.19 181/215 nt 83.72 180/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.16.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gtctggatctccttcagcaattatgccatccactgggtccgccaggctccagggaagggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14107 JY8QFUQ01CDH08 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - gcctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14108 JY8QFUQ01AGKHP productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame - ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14109 JY8QFUQ01BK7AV productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14110 JY8QFUQ01BAIFQ No results +14111 JY8QFUQ01CCRU2 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 973 94.06 206/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame - gcctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14112 JY8QFUQ01CC9NQ productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CATISDYRFEFW in-frame + ctctggattcacctttagtggctattggatgagttgggtccgccaggctccggggaagggtctggagtgggtggccaacatagagaaagatggaagtgacataaagtatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtctctgcaaatgaacagcctgagagccgacgacacggctatttattactgtgcgaccattagtgactaccgatttgaattctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +14113 JY8QFUQ01A32YE productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14114 JY8QFUQ01B5ZU7 unproductive (see comment) Homsap IGHV4-61*08 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); ctctggtgcctccatcagcagtagtggtcactactggagttggatccggcagcccccagggaagggactggaattcattggaaaaaCtctattccaatgggaacgccaactacaacccctccttcaagagtcgagtcaccatttcagtggacacgtccgagaaccagttctccctgagcctgaggtctgtgaccgctgcggacacggccctttattactgtacgagggggggtatacacttatgacagcccgtggggccaggggcattcaggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14115 JY8QFUQ01C90EK productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14116 JY8QFUQ01B8SJV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14117 JY8QFUQ01B4CAM productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + ctctacattcgcctttagcaactatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14118 JY8QFUQ01CM9Y8 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F (see comment) 662 77.98 170/218 nt 77.52 169/218 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [2.16.38.11] CAREDIVREGLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (77,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gtgtctggtggctccatcgccacttatcattggtggaattgggtccgccagaccccgggaagggactggagtggattggagaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14119 JY8QFUQ01BWGPB unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDSRHSASGSYSDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactgggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14120 JY8QFUQ01DAM5H No results +14121 JY8QFUQ01AYDLJ No results +14122 JY8QFUQ01ADU0D unproductive Homsap IGHV4-61*02 F 965 93.21 206/221 nt 92.76 205/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 2 10 7 X 10.7.X [2.17.37.11] CATVARR#AFDIW out-of-frame - in FR3-IMGT, from codon 96 of V-REGION: 1 nucleotides (from position 196 in the user submitted sequence), (cause frameshift) tcgtctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgaccccgcagacacggccgtttattactgtgcgacagtggcgcgccgggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14123 JY8QFUQ01BEJAX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctgatttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +14124 JY8QFUQ01CCM83 productive (see comment) Homsap IGHV3-7*01 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 8 14 7.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) cctctggatttacttttacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcag +14125 JY8QFUQ01AS9Y7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + tctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14126 JY8QFUQ01CNN46 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14127 JY8QFUQ01BLZ8K No results +14128 JY8QFUQ01DRPB2 No results +14129 JY8QFUQ01C3F1P productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 952 94.37 201/213 nt 93.9 200/213 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [0.16.38.11] CARDGGHSYGPSFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) tggatacaccttcaccaggtacattatgcactgggtgcgacaggccctggacaagggcttgagtggatgggaataatcaaccctagaggtgttagcagaagctacgcacagaagttccagggcagagtcaccatgaccaccgacacgtccacgagcacagtctatatggagctaaacagcctgagatctgaggacacggccgtttattactgtgcgagagatggagggcacagctatggaccctcctttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +14130 JY8QFUQ01DH40M productive Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + cctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +14131 JY8QFUQ01CSF7P unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 389 65.84 133/202 nt 8 8 X 8.8.X [1.17.32.X] null + No rearrangement found Low V-REGION identity (65,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcccctttagcaactatgccatgacctgggtccgccaggctccaggggagggactggaatgggtctcaagtattagaggtagtggtgacaggacatcctacgcagactccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14132 JY8QFUQ01C248S No results +14133 JY8QFUQ01B2EP4 productive Homsap IGHV4-61*02 F 1010 95.48 211/221 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 10 7 14 10.7.14 [1.17.38.11] CARAGYYYGSGSYFEW in-frame + tctctggtgactccatcagcagtggcagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtttctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagctttccctgaagctgacgtccgtgaccgccgcagatacggccgtgtattattgtgccagagcgggttattattatgggtcggggagttacttcgagtggggccagggaaccctgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14134 JY8QFUQ01BWC6T productive Homsap IGHV3-21*04 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14135 JY8QFUQ01B5R9J No results +14136 JY8QFUQ01A2FHS productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1105 100.0 222/222 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [2.17.38.11] CARSRTFYGSANYW in-frame - gtctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14137 JY8QFUQ01AYNJ8 No results +14138 JY8QFUQ01CPQSF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttccccca +14139 JY8QFUQ01C2YDS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagAccctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctctgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14140 JY8QFUQ01A3IIQ productive (see comment) Homsap IGHV3-7*01 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSDFYSTGHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); ggctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14141 JY8QFUQ01BIGJ3 No results +14142 JY8QFUQ01AQDEK unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14143 JY8QFUQ01BKNRL unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*05 F 157 54.19 97/179 nt 8 7 X 8.7.X [1.17.26.X] null + No rearrangement found cctctgcattcaccttcagtagctacgacatgcactgggtccgccaagcaacaggaagaggtctggagtgggtctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14144 JY8QFUQ01C73TY productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 956 92.76 205/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARRGSYGSGSYYPW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggcgccatcagcagtaatagttactactgggactggatccgccagcccccagggaaggggctggagtggattgggagtatgttttatactggggtcaccttctacaacccgtccctcaagagtcgagttaacatttccgtggacacgtccaagagccagttctccctgaggctgagctctgtgaccgccgcagacacggctgtgtatcactgtgcgagacgtggttcctatggttcggggagttattatccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14145 JY8QFUQ01A5DBU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctcctccaggagcacctccgagagcacagcggccctgggctgcctgtcaaggactacttccccgaacggtgacggtgtcgtggaactca +14146 JY8QFUQ01BQ9NT No results +14147 JY8QFUQ01DTUZL No results +14148 JY8QFUQ01DS1AX productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +14149 JY8QFUQ01CYGW1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14150 JY8QFUQ01B254T No results +14151 JY8QFUQ01COOTQ productive (see comment) Homsap IGHV3-30*01 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 7 11 8.7.11 [1.17.38.11] CACGHMRDGYDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14152 JY8QFUQ01DM8TO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ1*01 F 89 63.46 33/52 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaaggggaccacggtcaccgtctcctcagcctccgaccaagggcccatcggtcttccccctggcaccctcctccaagagcagcctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +14153 JY8QFUQ01A5EZX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKRLQAVADDAFDF## out-of-frame + cctctggattcatctttagtagctatgccatgggctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgagcagcctgagagccgaagacacggccatatattactgtgcgaaaaggttgcaagcagtggctgatgatgcttttgatttctggggcccaagggacaatggtcaccgtctcctcagatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14154 JY8QFUQ01AU2BA productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14155 JY8QFUQ01DHKLW unproductive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CAKLADTGEWSNRIFSF#W out-of-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttcatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14156 JY8QFUQ01CM07M productive Homsap IGHV4-34*08 F (see comment) 733 82.41 178/216 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-9*01 F 1 8 7 14 8.7.14 [2.17.38.11] CAKSRIGWFNDAFDVW in-frame - Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtggattggggaaatcaatcacagtggagacaccaattacaacccgtccctcaggagtcgagtcatcatttcaatagacacgtccaagagcgaattctccctgaagatacactctgtgaccgccgcggacacggctatatattactgtgcgaaaagtcgaattggctggttcaatgatgcatttgatgtctggggccaagggacaagggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14157 JY8QFUQ01AUI3L productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14158 JY8QFUQ01COOH3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [0.17.38.11] CVKDISRSGCFEYW in-frame - tggattccagtttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14159 JY8QFUQ01BCNRJ No results +14160 JY8QFUQ01CJEU1 unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 X 8.7.X [4.17.38.11] CARGAPIL** (see Functionality comment) out-of-frame - stop codons, IMGT/JunctionAnalysis gives no results for this JUNCTION cgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggcccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14161 JY8QFUQ01AXRQG unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 644 93.84 137/146 nt 93.15 136/146 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD3-16*01 F 2 8 X X 8.X.X [1.8.31.11] CARRDVGLHAFDL## out-of-frame + in FR2-IMGT, from codon 47 of V-REGION: 72 nucleotides (from position 54 in the user submitted sequence), (do not cause frameshift) gttctggatccaattttaactacgactggatcggctgggtgcgccagatgcccggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgcttttgatctgtggggccaggggtacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +14162 JY8QFUQ01DFIIV productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14163 JY8QFUQ01CMXUR unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccggcaAaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcaccatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttggcaggcgaggcaacctggtcaccgtctctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacatggtcgtcgcatgcctggtccagggcttcttccccca +14164 JY8QFUQ01CE504 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +14165 JY8QFUQ01BY2NW productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcatcttcagtagctactggatgcactGgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +14166 JY8QFUQ01DCGS5 productive (see comment) Homsap IGHV3-7*01 F (see comment) 688 80.09 173/216 nt 79.17 171/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 7 8 15 7.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) ctctggattcgtctttactaatcatggatgagttGgggtccgccaggccacagggaaggggccggagtgggtggccaacatatcccccagacggaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14167 JY8QFUQ01CFG7V No results +14168 JY8QFUQ01DVGZS unproductive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CARVIPGRGKLC#FDVW out-of-frame + ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggcaaactatgctttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +14169 JY8QFUQ01DUMXO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame - cctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14170 JY8QFUQ01A50XT productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 892 89.95 197/219 nt 89.04 195/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [2.17.38.11] CSKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gcctctggattctccgtcagtaAgttactggatgcactgggtccgccaggctccagGgggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14171 JY8QFUQ01AVHVI productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14172 JY8QFUQ01BSI3K productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcagccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14173 JY8QFUQ01AX7IZ productive (see comment) Homsap IGHV4-61*02 F 1023 96.36 212/220 nt 95.91 211/220 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD5-18*01 F 3 10 7 18 10.7.18 [1.17.37.11] CARGSFRDGGHGYGPWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 119 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagcagtggaagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatttatatcagtgggggcaccgactacaaccctccctcaagagtcgagtcaccatatcggcagacacgtccaagaaccagttctccctgaagctgatctctgtgaccgccgcagacacggccgtgtattactgtgcgagaggttctttcagagacggtggacacggctatggcccctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14174 JY8QFUQ01DUQ3Y productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 926 90.62 203/224 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD2-21*01 F 2 8 10 8 8.10.8 [1.17.38.11] CTSNSWLDRW in-frame - cctctggattctctttcagtaatgcctggatgaattgggtccgccaggctccagggaaggggctggaatgggttggccatattaaaagggaaattgatggtgggataacaaactacgctgcacccgtgaagggcagattctccatcgcaagagatgattcaaagaatatgatgtatttgcaaatgaacagcctgaacaccgaggacacaggcgtgtattactgtacctcaaattcgtggctcgaccgctggggccagggaacccccgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14175 JY8QFUQ01AFVNN No results +14176 JY8QFUQ01CNXZ5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14177 JY8QFUQ01ADZFS productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +14178 JY8QFUQ01CVY8N productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F 845 88.37 190/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARISAFDQW in-frame + tacacggcgggtccttcaaaggttactattggagctggatccgccagcccccaggaaaggggctggagtggattggagaaatcgaccatagtggaaacaccaactacaacccgtccctcaagagtcgagtcaccgtgacagttgacacatccaagaaccaaatttccctgaatttgacctctgtgaccgccgcggacacggctatttattactgtgcgcgtatttcagcctttgaccagtggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +14179 JY8QFUQ01A0MXA unproductive Homsap IGHV3-11*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CARRLLSSGWPPHDG#SW out-of-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgactactacatgtcgtggatccgccaggctccaggaaAaggggctggagtgggtctcatacattagtagtagtggtaattccatatactacgcagactctgtgaggggccgattcaccacctccagggacaacgccaagaattcgatatatctacaaatgaacagcctgagagccgacgacacggccgtttatttttgtgcgagaagacttctgagcagtggctggccaccccacgatggggctcctggggccagggaacccacgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14180 JY8QFUQ01CR1U3 productive (see comment) Homsap IGHV1-3*01 F 849 88.79 190/214 nt 88.32 189/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacagcttcactaatcacattatccattgggtgcgccaggCcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14181 JY8QFUQ01CXEZ8 productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 965 92.79 206/222 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD1-26*01 F 3 8 10 21 8.10.21 [1.17.38.11] CTRDATDNGRYYLGSGYFGMDVW in-frame - tctggattcatctttggtgattacgcnatgcactggttccgccaggctccagggaaggggctggaatgggtaggtttcattagaagtacagcttatggtcagacaacacaatacgccgcgtctgtgagaggcagattcaccatctcaagagatgattccaaaagcagcacctatctgcaaatgaatagcctgaaaagcgaggacacagccgtgtattactgtaccagagacgccacagataatgggagatactacctcggctcgggatatttcggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14182 JY8QFUQ01CECLX productive (see comment) Homsap IGHV1-2*02 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [0.17.38.11] CARDGISMTLVRGVRPFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); tggatacaccttcatcggccattaCtatacattgggtgcgacaggcccctggacaagggcttgaatgggtggggtggatcaaccctaacagtggtgttacaaactatgcacagcagtttcaggacagggtcaccatgaccgtcgacacgtccatcagcactgcctacatggacctcaaaagtctaaagtctgacgacacggccatctattactgtgcgagagacggaataagtatgactctggttcggggagttaggcccttcgactactggggccagggaaccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14183 JY8QFUQ01BI87O productive Homsap IGHV4-61*02 F 848 87.33 193/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 10 7 11 10.7.11 [1.17.38.11] CARSGWDNQFDFW in-frame + tctctggtgtcgccaccagtagtggcacttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaacccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccacagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcatcgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14184 JY8QFUQ01ASNEE productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14185 JY8QFUQ01C0VRM productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14186 JY8QFUQ01AGYJ3 No results +14187 JY8QFUQ01CHYBT unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 814 86.57 187/216 nt 86.11 186/216 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD6-6*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDSGPSGYARYESMDV## out-of-frame + in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); tctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggaggggcgtggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaGggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctgggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactattccccgaaccggtgacggtgtcgtggaactcag +14188 JY8QFUQ01AKHHA No results +14189 JY8QFUQ01BBC42 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 890 90.7 195/215 nt 89.77 193/215 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.16.37.11] CVSDLAGQKGF# out-of-frame + in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 167 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaagggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14190 JY8QFUQ01BANLS productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 804 86.45 185/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CGTSSRAWGADAFDIW in-frame + ctctgggctcagcgtcagtaactaccgcatgggctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagagatgatagtacagatcatgtagattccgtgaagggccgattcaccgtttcccgagacaattccaagaacacattgtaccttcagatgaacagtgtgacagccgaggacacggccgtttattattgtggaactagttcccgcgcctggggcgctgatgcctttgatatctggggccaggggacactggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccctagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14191 JY8QFUQ01DM3BO productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +14192 JY8QFUQ01AFV6Z No results +14193 JY8QFUQ01B8AYU unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*03 F 3 8 8 X 8.8.X [1.17.38.11] CVRSPPSYIWRW*DG#FDHW out-of-frame + stop codons Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggtcgttgtttagcaactatgccatgagttgggtccgccaggctccagggaaggggctggagtgcgtcgcagctatcagtggtaatggtgctgacacaaggtacgcagactccgtgaagggccgactcaccatctccagggacaacgtcaataagagggtgtatttggaaatgaagagcctgagagtcgaggacacggccacatattattgtgttagatcccccccgtcttatatatggagatggtaggacggacttttgaccactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14194 JY8QFUQ01AFNVU No results +14195 JY8QFUQ01AJGW3 No results +14196 JY8QFUQ01DEWDW productive (see comment) Homsap IGHV4-61*02 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-9*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARCPNYNIGTPGGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaaggGgaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggaccccggggggctttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +14197 JY8QFUQ01CGTDW productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1053 96.46 218/226 nt 96.02 217/226 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tccgggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtCccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggctttttcccc +14198 JY8QFUQ01BVB0R productive Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame - Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14199 JY8QFUQ01CXUDL productive Homsap IGHV3-21*04 F 873 88.94 193/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAKGYHGPFDSW in-frame - ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactacgcagactctgtggagggccgattcaccatctccagagacaacgccaagaacacgatgtatctgcaaatgaacaccctgagagacgaggacacggccgtctatttctgcgcgaaaggttaccacggcccctttgactcttggggccggggaaccctggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14200 JY8QFUQ01AXKB6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14201 JY8QFUQ01CLU61 productive Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame + Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14202 JY8QFUQ01A53BA productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14203 JY8QFUQ01DLU5K productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14204 JY8QFUQ01B3LHZ productive Homsap IGHV4-39*03 F 915 90.87 199/219 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + ctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacagccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14205 JY8QFUQ01BN8CT No results +14206 JY8QFUQ01BMPYC productive Homsap IGHV3-74*03 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKVDSDGWHGTIDRW in-frame + ctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggatagcgatggctggcacggaacaatagaccgctggggccagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14207 JY8QFUQ01DWRQL No results +14208 JY8QFUQ01AYL0X productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 807 93.48 172/184 nt 92.93 171/184 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.6.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 33 nucleotides (from position 35 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcagtagttactggatgcactgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14209 JY8QFUQ01CRML5 productive Homsap IGHV3-9*01 F (see comment) 749 83.96 178/212 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 7 8 16 7.8.16 [X.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Low V-REGION identity (83,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14210 JY8QFUQ01BFJMN productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 91.28 199/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'A' (1 nucleotides at position 139 to 139 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'G' (1 nucleotides at position 193 to 193 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccAatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaGggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14211 JY8QFUQ01CDNWM unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 94.17 210/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 X 8.10.X [1.17.37.11] CTTGGWN*L##W out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 162 in the user submitted sequence), (cause frameshift) cctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacaggggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14212 JY8QFUQ01BBSWK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 901 90.41 198/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDLYGADDLW in-frame - acctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14213 JY8QFUQ01AOGGT productive Homsap IGHV3-7*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame - cctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14214 JY8QFUQ01AYGBK No results +14215 JY8QFUQ01BPUXF No results +14216 JY8QFUQ01CNGMT unproductive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F or Homsap IGHV3-33*03 F 1035 97.7 212/217 nt Homsap IGHJ3*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD4-11*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAGPVTTNYYYYV#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) gtctggattcaccttcagtagctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcatttatacggtatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcggggcccgtaactacgaactactactactacgtgatgacgtctggggccaagggaccacggtcaccgtctcctcagggagtgcatccgccccaaccc +14217 JY8QFUQ01BJIED productive Homsap IGHV3-48*02 F 864 88.94 193/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD6-6*01 F 1 8 8 20 8.8.20 [1.17.38.11] CARDDSRLWSSSFNHYFAMDVW in-frame + ctctggattcacctttagtgattatagaatgaattgggtccgccaggctccagggatggggctggaatgggttgcacacattagtaccagtggtagtagtatatactatgcagactctgtgaagggccgattcaccgtctccagagacgatgccaagaattcactttttctgcaaatggacagcctgagagacgacgacacggctgtatattactgtgcgagagacgattcacggctgtggagctcgtcatttaaccactatttcgctatggacgtctggggccaagggaccaccgtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14218 JY8QFUQ01DFG5Q productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 836 87.91 189/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.38.11] CARGRTVVTVIDYIDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctgggggActccattagtggttactattggacgtggatccggcagAcccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14219 JY8QFUQ01BNGAT productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1034 95.98 215/224 nt 95.54 214/224 nt Homsap IGHJ6*02 F 230 90.91 50/55 nt Homsap IGHD3-16*01 F 1 8 10 10 8.10.10 [1.17.38.11] CITDLVYGMDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggattcacttttaataacgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaAaaaccgaaactgatggttggacagcagaccacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcaaagaacacgctgtatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattattgtatcacagatttggtctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt +14220 JY8QFUQ01AJ6J6 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 782 83.48 187/224 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-22*01 F 2 8 10 11 8.10.11 [1.17.38.11] CTWDSTGYFRLTW in-frame - Low V-REGION identity (83,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggactcactttcagtgacgcctggatgacctgggtccgccaggttccagggaagggctggagtggggttgcccatattagatggaactctgatgactggaccacagactacgctactcccgtgaagggcagattcaccatctcaaaagatatttcagagaacacgctgtatctacaaatgaacagcctgataagcgaggatacaggcgtttattactgtacctgggacagcactggttattttcggcttacctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14221 JY8QFUQ01AX3Y3 unknown (see comment) Homsap IGHV3-7*01 F 1026 96.77 210/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +14222 JY8QFUQ01C5CP6 productive (see comment) Homsap IGHV3-7*02 F 1004 95.87 209/218 nt 95.41 208/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaagGggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14223 JY8QFUQ01DC98A No results +14224 JY8QFUQ01BXTDZ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-13*01 F 3 8 7 12 8.7.12 [2.17.38.11] CARGVGQQLPPLDW in-frame - gtctctcgtgcctccatcaatatttcctactggagctggatccggcagcccccagggaggggactggagtggattggatatatctatgatagtgggagtaccaactacaacccctccctcaagagtcgagtcaccatatctatagacacgtccaagaaccagttctccctgaggctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgaggggggtggggcagcaactgccccccttagactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14225 JY8QFUQ01B89S0 productive (see comment) Homsap IGHV3-72*01 F 958 92.0 207/225 nt 91.56 206/225 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 10 14 8.10.14 [2.17.38.11] CARLHYSGGWYGLDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtgaccactacatagactgggtccgccaggctccaggaaAaggggctggagtgggttggccgtactcgaaataaagctaacggttacagtacagagtatgccgcgtctgtgaaaggcagattcaccgtctcaagagataactcagagaacttagtgcatctgcaaatgaacagcctgaaaagcgaggacacggccctgtattactgtgctagactgcactacagtggtggctggtacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14226 JY8QFUQ01AT1SV productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARDMGSGRYFEPYDYW in-frame - gggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14227 JY8QFUQ01A5NXH unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 791 85.58 184/215 nt 85.12 183/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame - stop codons in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttaTacttaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14228 JY8QFUQ01C7UHC productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.37.11] CARDMGSGRYFEPYDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 83 of V-REGION: 1 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattcaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14229 JY8QFUQ01AZ6JH unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 580 74.07 160/216 nt 73.61 159/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (74,07% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaAaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +14230 JY8QFUQ01A2XE0 unproductive Homsap IGHV3-48*01 F 1100 100.0 221/221 nt 99.1 219/221 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [2.17.38.11] CASRLRSSGGY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); cagcctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaaggggctggagtgggtttcatGacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14231 JY8QFUQ01DFZ5Q productive (see comment) Homsap IGHV3-48*01 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [1.16.38.11] CAKDRITIFSYNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccaggagggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14232 JY8QFUQ01AQJEX No results +14233 JY8QFUQ01AGZ4S unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 84 51.52 68/132 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons tctggattcacctttaacatgtatgtcatgcactggttccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14234 JY8QFUQ01AUNK1 productive (see comment) Homsap IGHV1-24*01 F 957 94.39 202/214 nt 93.93 201/214 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD3-16*01 F 2 8 8 11 8.8.11 [0.17.38.11] CVGDVGWGYPQGW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); cggatacaccctcaatgaattatccatgcactgggtgcgacagactcctggaaaagggcttgagtcgatgggcggAttttgatcctgaatatggtaaaacaatctacgcgcagaagttccagggcagagtcaccatgaccgaggacacatctgcagacacagcctacatggagttgagaagcctgagatttgaggacacggccgtgtattattgtgtcggagatgtcggctggggatacccccaaggctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14235 JY8QFUQ01DE82D unknown (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F (see comment) 549 76.72 145/189 nt 8 8 X 8.8.X [1.17.28.X] null - No rearrangement found Low V-REGION identity (76,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttgatgattttgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaggatagtctatgcggactctgtgaagggccgattcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14236 JY8QFUQ01BH0D4 No results +14237 JY8QFUQ01BWBZS productive (see comment) Homsap IGHV3-72*01 F 952 92.34 205/222 nt 91.89 204/222 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 10 14 8.10.14 [1.16.38.11] CARLHYSGGWYGLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgaccactacatagactgggtccgccaggctccaggaaaggggctggagtggttggccgtactcgaaataaagctaacggttacagtacagagtatgccgcgtctgtgaaaggcagattcaccgtctcaagagatgactcagagaacttagtgcatctgcaaatgaacagcctgaaaagcgaggacacggccctgtattactgtgctagactgcactacagtggtggctggtacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14238 JY8QFUQ01AB75W productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 761 83.49 182/218 nt Homsap IGHJ3*02 F (see comment) 142 76.0 38/50 nt Homsap IGHD1-1*01 F 3 8 8 17 8.8.17 [1.17.38.11] CAKDIWAREWNDMAAFQMW in-frame + Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cccccggaatcatttttcccagctatgtcatgagttgggtccgccaggccccagggaaggggctggagtgggtcgcaagcattagtgccaggggcgacagttcatactacgcagactccgtgaagggccgattcaccatctccagggacaatcccaggaccacattgtatctggaaatgaacagtctgagagtcgaagacacggccacatattattgtgcgaaagatatctgggcgcgagagtggaacgacatggcggcttttcagatgtggggccaggggacacttgtcattgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14239 JY8QFUQ01DJOGY No results +14240 JY8QFUQ01AT8HH productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 803 85.07 188/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 3 10 7 11 10.7.11 [1.17.38.11] CAGGEDPFKVRHW in-frame + tctctggtggctccttttctaatcatggttaccactgtagttggctccgccagttcccagggaaggacctggagtggattgcctacatctattacactgggagcaccgagtataacccgtccctcaggagtcgagttgccatatcagtggacacgtctgggaaccagtgttccctggagttgaactctgtgagtgccgcggacacggccgtctattactgtgcgggaggcgaggatcccttcaaagttcgacactggggccagggaacccgggtcaccgtctcctcagcatccccggaccagccccaagggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga +14241 JY8QFUQ01CPS2S unproductive Homsap IGHV4-61*02 F 894 89.24 199/223 nt 88.34 197/223 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [2.17.37.11] CAREFWRFLQFSG#YW out-of-frame - in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 118 in the user submitted sequence), (cause frameshift) ctgtctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattAgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagaattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14242 JY8QFUQ01CQ7EP productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 869 86.78 197/227 nt 85.46 194/227 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*02 F 2 8 10 12 8.10.12 [2.17.38.11] CSYFRHEPYHFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tagacgctggattcgcctctggtgattatgctatgaGgttggttccgccaggctccgggaaaAGggggctggagtgggtggGggttcatcagaagcagagcttacactgggacaccagaatacgccgcgtctgtgaaaggcagattcaccatctccagagatgcttccaaaagtattggctatctgcaaatgaacaatctgaggatcgaggacacagccgtctattattgctcttattttcggcatgagccatatcactttgactattggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14243 JY8QFUQ01CC78V productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 905 90.83 198/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14244 JY8QFUQ01AX9R5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14245 JY8QFUQ01B6BDJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKKHYNSGTYLYNFDYW in-frame + ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaaagcattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +14246 JY8QFUQ01C3T6M productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 912 92.06 197/214 nt 91.59 196/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARRDVGSHAFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); tggatacaattttaactacgactggatcggctgggtgcgccagatgcCccgggaaaggcctggagtggatggggatggtctatgttggtgactctgatgctagatacagcccgtcctccgaaggccaggtcaccatctcagccgacaaggccatcagtaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggatgtgggttcacatgctttcgatctgtggggccaagggacaatggtcaccgtttcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14247 JY8QFUQ01BQGVY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVKGWNYHSATFGFDYW in-frame - ctctggattcacctttagtgactatgccataagctgggtccgccaggctccaggaaaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccattttcagagacaactccaaagacacgctgtatctgcaaatgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaacctttgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14248 JY8QFUQ01DMS85 No results +14249 JY8QFUQ01BOY6X productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +14250 JY8QFUQ01B2FBT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKLENSSGNEDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctgaattaacgtttgatatatatgccatgacttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactggtagtggtgataatgcctactacgcagacttcgtgaagggccgattcgccatctccagagacaattccaagaacatgttgtatttgcaaatgaacaacctgcgaggcgaggacacggccgtttattactgtgcgaaactggaaaatagcagtgggaatgaagactcctggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +14251 JY8QFUQ01B325I productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 767 83.26 184/221 nt 82.81 183/221 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD3-3*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARRWSGTYPFASW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctcactcagaagtagtagtcaccattggggctggattcgtcagTccccccgggaaggggctggagtggcttgggactgtcgactttcgtgggaccacccactacaacccgtccctcatgggtcgactcacgatatccgtcgacgcgcccaagagtcaaatgtccctgcacttgagctctgtgaccgccgcagacacggctttttacttctgtgcgagacgctggagtgggacttatccgtttgcctcctggggccagggcatcccggtcatcgtctccccagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtccgtggaactcag +14252 JY8QFUQ01BYCK4 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 448 70.1 136/194 nt 8 7 X 8.7.X [1.17.31.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BYCK4 ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (70,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14253 JY8QFUQ01A3R6Q productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1049 96.04 218/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + ctccgggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccc +14254 JY8QFUQ01AM7BU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 738 82.49 179/217 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame - Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14255 JY8QFUQ01CG6Q8 No results +14256 JY8QFUQ01C55F1 unknown (see comment) Homsap IGHV3-74*03 F 117 54.07 73/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtacctactggatgcactgggtccgccaagttccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14257 JY8QFUQ01C92G5 productive Homsap IGHV3-33*04 F (see comment) 703 80.37 176/219 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [2.17.38.11] CARDILDYW in-frame - Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcatttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14258 JY8QFUQ01DTK17 unproductive Homsap IGHV3-72*01 F 1093 98.67 222/225 nt 98.22 221/225 nt Homsap IGHJ6*04 F (see comment) 108 66.67 36/54 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [2.17.38.11] CLRPPRYDP## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift); gcctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcCaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14259 JY8QFUQ01CJDYI productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 100.0 190/190 nt 99.47 189/190 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.7.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 28 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca +14260 JY8QFUQ01DQ3JG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14261 JY8QFUQ01AWWKU productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ttctggaGtacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14262 JY8QFUQ01CZ24N productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14263 JY8QFUQ01DMBXT unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 693 80.18 174/217 nt Homsap IGHJ1*01 F (see comment) 107 67.31 35/52 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLGLNAVYAFDV## out-of-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcgcttttggagattatgccatgaactgggtccgccaggccccagggaagggactggagtgggtctcaggtttgagcggtagaggcgtcagcaaatattatgcagactccgtgaggggccggttctccatttccagagacaactccgggagcgaggcagtccttcaaatgagcagcctgagagtcgaggacacggccacttactactgtgcgaggggcctagggcttaatgctgtctacgcatttgacgtctgggggacaggggaccacggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14264 JY8QFUQ01CWSL1 No results +14265 JY8QFUQ01A2FU8 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 888 86.13 205/238 nt 85.71 204/238 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 10 7 12 10.7.12 [7.17.38.11] CARRHYGEGLFDYW in-frame - Potentially, because of detected insertion/deletion in FR1-IMGT at codon 26 of V-REGION: 'C' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); gagactctcctgcactgtcCtttggtggctccatcaccaataataattacttctggggctggatccgccagcccccagggaaggggctggagtggattggggatgtccagtatagtgggagcacctactccagcccgtccctcaagaggcgggtcaccatgtctgtggacgtgtccaaaagtcaggtctccctgagactgagctctgtgaccgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14266 JY8QFUQ01CZIOF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 842 87.61 191/218 nt 87.16 190/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-8*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDRIGSLYYFDHW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 79 of V-REGION: 'A' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatcAtccagagacaacagcaaaaactccctgtatctgcaaatgaacagtctgagaactgaggacaccgccttgtattactgtgcaaaagataggattgggtccttgtactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14267 JY8QFUQ01CRG3F No results +14268 JY8QFUQ01DTOZ0 productive (see comment) Homsap IGHV3-7*01 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); tctacattcacgGtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14269 JY8QFUQ01DSXI7 unknown (see comment) Homsap IGHV1-2*03 F 83 57.35 39/68 nt 55.88 38/68 nt 8 X X 8.X.X [0.13.X.X] null - No rearrangement found in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) tggatacaccttcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14270 JY8QFUQ01DDKKR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccgag +14271 JY8QFUQ01AXH8G productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD7-27*01 F 2 8 7 7 8.7.7 [1.17.38.11] CARSQGDYW in-frame + tctctggtggctccatcagtccctacccctggagctggatccggcagtccccagcgaagggactggagtggattggctttatcttttacaatgggaccaccatctacaacccctccctccagagtcgactcaccatttcaatagacacatccaagaaccagttctccctgaaattggcctctgtgactgctgcggacacggccatatattattgtgcgagatcacagggggactactggggccggggagcccgggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca +14272 JY8QFUQ01DFHF6 unproductive (see comment) Homsap IGHV3-48*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARERGNSYGE##DYW out-of-frame - stop codons tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagacttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14273 JY8QFUQ01BZURD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDPGNYWGYYYDS## out-of-frame + gtctggatttacctttagtgattatgccttgagctgggtccgccagactcccgggaaggggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgagagatccgggaaattattggggatactattatgactcttggggcctggggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14274 JY8QFUQ01DQZS4 No results +14275 JY8QFUQ01DPBOX productive (see comment) Homsap IGHV4-4*07 F (see comment) 683 80.0 172/215 nt 79.53 171/215 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD2-8*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARECTNEAGGPRHLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); tctctggtgGgccccatcaatagtagtgactactattggacttggatccggcagcccgccgggaggggactggaatgggtcgggcgtgtcttcatgaatggccttaccgactacaatccatccttcggcagccgtctcaccatgtccattgacatgtcgaagaaccaattctccctgaagttgacctctgtgaccggcgctgacacggccctttattactgtgcgagagaatgtactaatgaggctggcggaccgagacacctggactcctggggccacggaactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14276 JY8QFUQ01BURVQ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame + cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +14277 JY8QFUQ01BHF2R productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARDRRPLREFDCW in-frame + ctctggattcaccctctccagctatgctatgcactgggtccgccagtctcccggcaaggggctagagtgggtggcagctatttcatatgatggaagtaaaatatattacgcagactccgtgaggggccgcttctccatctccagagacagttccaagaacactctgcatttgcaaatggacagcctgagacctgaggacacggctacatattactgtgcgagagatagacggccacttagggagtttgactgttggggccagggaaccccggtcgccgtctcctcggcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggctt +14278 JY8QFUQ01DURLP unproductive Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD5-12*01 F 2 7 8 X 7.8.X [1.17.38.11] CARDQVTEDY## out-of-frame - in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactgggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14279 JY8QFUQ01BJ5LY unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 850 88.43 191/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD3-10*02 F 2 8 7 X 8.7.X [2.17.38.11] CAREFPGAFFGQ#YGMDVW out-of-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctcgggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttccgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14280 JY8QFUQ01C60GD productive (see comment) Homsap IGHV3-7*01 F 977 94.5 206/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 7 8 11 7.8.11 [2.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) gtctctggattcaccttagtagggtttggatgacctgggtccgccaggGgtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14281 JY8QFUQ01BNT82 No results +14282 JY8QFUQ01A0D5E productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 808 86.85 185/213 nt 86.38 184/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 7 8 12 7.8.12 [0.17.38.11] CVKDISRSGCFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 8 in the user submitted sequence), (cause frameshift) tggattccagttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +14283 JY8QFUQ01A7RNH No results +14284 JY8QFUQ01DJIV3 productive (see comment) Homsap IGHV3-7*01 F 853 87.0 194/223 nt 86.55 193/223 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [3.17.38.11] CGRDERGADLPNDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); tgcagcctntggattcaccgttagtaggtattggatgagctgggtccGgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagccccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctggggcctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14285 JY8QFUQ01DM280 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 878 89.45 195/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + cctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14286 JY8QFUQ01BAR43 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 841 87.96 190/216 nt 87.04 188/216 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 8 8 15 8.8.15 [1.16.38.11] CAKGDSPIASRLYIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ttctggattcacctttggtgattatgctatgagctgggtccgccaggctccagggaagggccggagtgggtctcagCcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14287 JY8QFUQ01BMLD6 No results +14288 JY8QFUQ01ANG2X productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14289 JY8QFUQ01AVLL5 No results +14290 JY8QFUQ01DK39Y unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 482 83.82 114/136 nt 82.35 112/136 nt 8 8 X 8.8.X [1.16.12.X] null + No rearrangement found Low V-REGION identity (83,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 33 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) tctggattcacctttaacagccatgccatgagttggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactca +14291 JY8QFUQ01CQ8ID No results +14292 JY8QFUQ01AXFNY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14293 JY8QFUQ01AVUNN No results +14294 JY8QFUQ01C0DFI productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14295 JY8QFUQ01C5MDA No results +14296 JY8QFUQ01B18V1 No results +14297 JY8QFUQ01AXWMP productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 843 87.27 192/220 nt 86.82 191/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARRHYGEGLFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); ctttggtggctccatcagcCaataataattacttctggggctggatccgccagcccccagggaaggggctggagtggattggggatgtccagtatagtgggagcacctactccagcccgtccctcaagaggcgggtcaccatgtctgtggacgtgtccaaaagtcaggtctccctgagactgagctctgtgaccgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14298 JY8QFUQ01BODTQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14299 JY8QFUQ01BV9UK productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 927 92.17 200/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14300 JY8QFUQ01AUOAK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactca +14301 JY8QFUQ01C00CS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14302 JY8QFUQ01A0Z8X No results +14303 JY8QFUQ01BXQJQ productive (see comment) Homsap IGHV3-7*01 F 1008 96.31 209/217 nt 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14304 JY8QFUQ01A5GJS No results +14305 JY8QFUQ01CI7FA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcactctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14306 JY8QFUQ01A9YC6 productive Homsap IGHV3-7*01 F 1045 97.72 214/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [2.17.38.11] CVSSPYFYDSNGYW in-frame - gcctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14307 JY8QFUQ01AGZYH No results +14308 JY8QFUQ01CPDZW productive Homsap IGHV4-61*02 F (see comment) 695 79.64 176/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERDRSIGGAADLDSW in-frame - Low V-REGION identity (79,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccagtgtacccgtcagtcgtggaggttactactggaattggatccggcagcccgccgggaaggggctggagtggattggacgtgttgacagtaatggattcgtcaggtacaattcctccctcaaaagtcgactatctatgtcactaaacacgtccaagaatcagatctccctgatactgaggtctgtgatcgccgcagacacggccgtgtatttctgtgcgagggaacgtgataggtcgattggcggagcggcagatcttgactcctggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14309 JY8QFUQ01DRFCG No results +14310 JY8QFUQ01DPEN4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 796 85.65 185/216 nt 85.19 184/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-3*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDGVRGLGAYYIYYFDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); tctggattcacctttggcctctatgccatgaactGgggtccgccagactccagggaaggggccggagtggctcgcaactatcagtggtagtggaagtaggtcattctacgcagactccctcaggggccgtttcaccatctccagagacaattccaagggcacggtgtacctggacatgaccaccctgggagccgacgactcggccgtgtattactgtgccagagatggagtccgtggccttggtgcttattatatctactattttgactcatggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14311 JY8QFUQ01BU8WP unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 342 61.75 134/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (61,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagctatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagaaatagtggtacttacacattttacgcagactccgtgtattactgtgcgaaagtttacaacagacactcgaccggatattgtagtggtggtagttgctactccggttatggaaactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +14312 JY8QFUQ01BXXGZ No results +14313 JY8QFUQ01AG9YX unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 860 88.53 193/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 79 62.0 31/50 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW# out-of-frame + stop codons cctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggcccaatgggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +14314 JY8QFUQ01C1FAL productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14315 JY8QFUQ01CAZ6Y productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 991 94.98 208/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CGRPPLYSSGWQHPFNFW in-frame - ggttctggatacaactttaccgactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcccggtgactctgatatcacatatagtccgtccttccaaggccaggtcaccatctcagtcgacaagtccatcagcaccgcctacctgcagtggaacagcctgaaggcctcggacaccgccatgtattattgtgggagacccccactatatagcagtggctggcaacatccttttaatttctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14316 JY8QFUQ01BHN4V unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 302 96.88 62/64 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found ctctggattcaccttcagcagctatagaatgaactgggtccgccaggctccagggaaggggctg +14317 JY8QFUQ01B3WD7 No results +14318 JY8QFUQ01C10TD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14319 JY8QFUQ01A9VP5 productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [0.17.38.11] CATSDVGARKFDYW in-frame - tggttacacctttaccagatatggtattagttgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcagcgtttccaatggtgacacaaactatgcacagaagctccagggcagagtcaccatgaccgcagacccatccacgagcacagcctacttggaactgaggagcctgacatctgacgacacggccgtatattactgtgcgacatctgacgttggagctcgaaagtttgactactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14320 JY8QFUQ01BX5R1 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14321 JY8QFUQ01BY6WB productive Homsap IGHV1-2*04 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARGDFFESSGFDYW in-frame - tggatacaccttcaccgcccactatatacactgggtgcgacaggcccctggacaagggcttgagtggatggggcggatcaaccctaatagtggtggcacaatttatgcacagaagtttcagggctgggtcaccatgaccagggacacatccatggacacagcctacatggaggtgagggggctcaaatccgacgacacggccgtctatttctgtgcgcgaggcgatttctttgagagtagcggctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14322 JY8QFUQ01DHN5R productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcatcccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14323 JY8QFUQ01CHFVD productive (see comment) Homsap IGHV3-7*02 F 1004 95.87 209/218 nt 95.41 208/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaagGggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttct +14324 JY8QFUQ01B0BBI productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 849 88.79 190/214 nt Homsap IGHJ6*02 F 121 66.13 41/62 nt Homsap IGHD3-16*01 F 1 8 8 20 8.8.20 [0.17.38.11] CARGGGSSKRQVKDYYNGLDVW in-frame + tggatacaccttcagcagttattatatacactgggtgcgacaggcccccggacaggggcttgagtggatggcaatgatcaacccaagtggtggtagtaccacgtacgcacagaagttccagggcagactcatcgtgaccagggacacgtccacgagtagtgtctacatggacctgagtagcctgagatctgaggacacgggcgtctatttctgtgcgagaggggggggttccagtaaacgtcaggtgaaggactactacaacggtctggacgtctggggccaagggaccagcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgaggtgtcgtggaactc +14325 JY8QFUQ01CGLZF No results +14326 JY8QFUQ01BLUPN unproductive Homsap IGHV3-7*01 F (see comment) 711 81.11 176/217 nt 80.18 174/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 69 60.42 29/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CARLKGLTHHDFYFDL# out-of-frame - Low V-REGION identity (81,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 67 of V-REGION: 'T' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'GG' (2 nucleotides at position 125 to 126 in the user submitted sequence), (cause frameshift); ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatcccccagacggaatacgaaatacTtttggggactctgtgaaGGgggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggcgtggcatcctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14327 JY8QFUQ01CG6VE unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 754 82.43 183/222 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 X 8.10.X [1.17.38.11] CATDSPYWI##AFDVW out-of-frame + stop codons Low V-REGION identity (82,43% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) tctgggttcgttttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagtcgaggacggaggcttgtacttctgtgccacggattccccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14328 JY8QFUQ01BAHNB No results +14329 JY8QFUQ01CMLTU unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +14330 JY8QFUQ01ABR6E productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccggtctcctcagcatccccgaccagccccaaggtcttcccgctgcagcctcctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaggag +14331 JY8QFUQ01ANSMV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [2.17.38.11] CAKDQSCIVGPCGFDYW in-frame - gcctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgt +14332 JY8QFUQ01BQACL productive Homsap IGHV3-7*03 F 851 88.07 192/218 nt Homsap IGHJ6*03 F (see comment) 174 82.35 42/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 and Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctccggattcatttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaaggggccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaaggatgggaacgtggtcgtcgcatgcctggtccaggggcttcttcccccagg +14333 JY8QFUQ01CJCDJ No results +14334 JY8QFUQ01CCACX productive (see comment) Homsap IGHV3-48*02 F 882 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 3 8 8 10 8.8.10 [1.17.38.11] CASGGVTEAHYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'T' (1 nucleotides at position 209 to 209 in the user submitted sequence), (cause frameshift); ctctggattcagctccagtgaatataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattggtgttggtactggtggcatatactacgcagactctgtgaggggccgattcaccatctccagggacaatgccgagaactcagtgcatctgcaaatgaacagcctgagagacgacgacacgggtgttTtattactgcgcgagcggaggggtgacagaggctcactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14335 JY8QFUQ01B4EUN unknown (see comment) Homsap IGHV3-64*02 F, or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 99 52.59 71/135 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons tctctggattcagcttcagtgactatggcatgggctgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14336 JY8QFUQ01AW22E No results +14337 JY8QFUQ01BFTC4 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14338 JY8QFUQ01AN0P3 productive (see comment) Homsap IGHV4-39*02 F 982 94.52 207/219 nt 93.61 205/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.16.38.11] CARIVVRQFDQW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 83 in the user submitted sequence), (cause frameshift) tctctggtgactccatttccagtactagttattactggggctgggtccgccagcccccagggaagggctggagtggattggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14339 JY8QFUQ01DDAXQ productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-6*01 F 1 8 7 12 8.7.12 [1.17.38.11] CVRSYSRTSEFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 2 nucleotides (from position 99 in the user submitted sequence), (cause frameshift) gtctggattcagtttcagtacctttggcatgagttggatccgccagacgccaggcaaggggctggagtgggtgacagttatatggtcggatggaactaaaaaattatgcagactccgtgaagggccgattcaccatctccagagacaatgtcaagaacacggtttatctgcagatgagcagcctgagagtcgaggacacgggcgtatattattgtgtgaggtcgtatagtaggacatctgagtttgactactggggcccgggaacccaagtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14340 JY8QFUQ01CNJAZ productive Homsap IGHV4-34*03 F 890 90.65 194/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 228 94.12 48/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CVRNYYDFSGYFNWFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tgtctggtgggtccttcagtggttactactggagttggatccgccagcccccagggaaggggctggagtggattggggaaatcaattatagaggaagtaccaactacaatccgtccctcaaaagtcgagtcaccgtgtcttcagacacgtccaagaatcagttctccctggagttgatctctgtgaccgccgcggacacggccatatattattgtgtgagaaattactatgattttagtggttatttcaattggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcancgctgcctggtcagggcttcttccc +14341 JY8QFUQ01CZIF6 productive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14342 JY8QFUQ01DQ5IL No results +14343 JY8QFUQ01DMCPH productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARVGATLSFDVW in-frame - cctctggattcaccctcagtagctataacatgaactgggtccgccaggctccagggaaggggctggagcgggtttcatacattagtattagtagtggtaccatatactatgcagactctgtgaagggccgattcaccatctccagggacaatgccgagaactcactgtatctgcaaatgagcagcctgagagccgacgacacggctgtgtattactgtgcgagagtgggagcgacgctttcttttgatgtctggggccaagggacaacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +14344 JY8QFUQ01DM9QB unproductive Homsap IGHV4-61*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD1-1*01 F 1 10 7 X 10.7.X [1.17.37.11] CARESKVISCPNWFD#PW out-of-frame + in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 117 in the user submitted sequence), (cause frameshift) tctggtgactccatcaccagtggtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaatcctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagggaaagtaaagtgatcagctgccccaactggttcgaccccctggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14345 JY8QFUQ01AXJWN productive (see comment) Homsap IGHV1-2*02 F 939 93.46 200/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 82 to 87 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14346 JY8QFUQ01CDE14 productive (see comment) Homsap IGHV3-48*01 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKGVIAVAGTTLTAG in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift); cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatTgaacagcctgagagccgaggacacggccgtatattactgtgcgaagggggttatagcagtggctggtacgactttgactgctggggccagggaaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggctgacggtgtcgtggaactc +14347 JY8QFUQ01AGTXI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.74 200/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + cctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14348 JY8QFUQ01B81A4 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*06 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 823 87.04 188/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [1.17.38.11] CARGDGYNFGGLDYW in-frame - tctggattcaacttcataggttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactccgtgaggggccgatccatcatttccagagacgattctaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14349 JY8QFUQ01AODKR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1035 97.7 212/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKDRITIFSYNWFDPW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14350 JY8QFUQ01A1W6G productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14351 JY8QFUQ01DMRBH productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 959 93.58 204/218 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcatctttgatgattttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14352 JY8QFUQ01ACU8V productive (see comment) Homsap IGHV3-11*01 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14353 JY8QFUQ01DHT73 productive Homsap IGHV4-61*02 F 1033 96.4 214/222 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 15 10.7.15 [2.17.38.11] CARAPSYTNSHQHCDYW in-frame - gtctctggtggctccatcaacagtggtagttactactggagttggattcggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctattattgtgcgagagctccctcttataccaactcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14354 JY8QFUQ01C2UOY productive Homsap IGHV3-72*01 F 931 90.67 204/225 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-8*02 F 2 8 10 17 8.10.17 [2.17.38.11] CTRDTTDTGGQSFNGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggtttccccttcagtgaccacttcatggactgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctggggccaggggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14355 JY8QFUQ01B14T7 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14356 JY8QFUQ01APKCI unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1040 97.71 213/218 nt 97.25 212/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 160 80.0 40/50 nt Homsap IGHD2-21*02 F 2 8 8 18 8.8.18 [1.17.38.11] CARPYCGGDCHNRGAF**SW in-frame + stop codons in FR3-IMGT at codon 76 of V-REGION: 'G' (1 nucleotides at position 134 to 134 in the user submitted sequence), (cause frameshift); cgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttGcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggctttttgatagtcctggggccaagggacaatggtcaccgtctcttcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttccc +14357 JY8QFUQ01AJ98V productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 781 83.78 186/222 nt 82.43 183/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [2.17.38.11] CARRWARQRLVIDYFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'GC' (2 nucleotides at position 108 to 109 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 71 of V-REGION: 'GT' (2 nucleotides at position 128 to 129 in the user submitted sequence), (cause frameshift); gtctctggtgactccatcagtagtactcattactattggggctggatccggcaGgcccccagggaggggactggagtgggttgggagtatccactacactgggagcaGCctacctacaactggtcccGTccaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatagactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14358 JY8QFUQ01A91DP No results +14359 JY8QFUQ01A8P07 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14360 JY8QFUQ01COINA No results +14361 JY8QFUQ01CMNZM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctctagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14362 JY8QFUQ01A4O9C productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 806 85.78 187/218 nt 84.86 185/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); cctctggattcacgttcagtaattacgacatgcactgggtccgccGaacctagaggaagaggtctggagtAgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14363 JY8QFUQ01C2AVU productive (see comment) Homsap IGHV1-8*01 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ3*01 F (see comment) 178 84.0 42/50 nt Homsap IGHD2-2*02 F 3 8 8 14 8.8.14 [0.17.38.11] CARLAAPLRAYALDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); ctggatacaccttcggcagttttgatatcaactgggtgcggcaggGcccctggacaagggcttgagtggatggggtggatgaaccctcacagtggtaacacaggatatgcagagaacttccagggcagagtcaccatgaccagggacacctccataagcacagcctacatggagctgagcagcctgacatctgacgacacggccgtatattactgtgcgagactagcagcacctttacgcgcctacgctttggacgtctggggccaagggaccgcggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14364 JY8QFUQ01ABVQT unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14365 JY8QFUQ01A1E6T productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 944 93.49 201/215 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [0.17.38.11] CARPFSGRWCFDLW in-frame - ctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14366 JY8QFUQ01BAI84 unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD2-8*01 F 2 8 8 X 8.8.X [1.17.37.11] CAKDRTLHTPAQMFYYGMDV## out-of-frame - in FR3-IMGT, from codon 70 of V-REGION: 2 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) atctggattcaccttcagttcttatagtgtaaactgggtccgccaggctccagggaagggcctagagtttgtctcatacattgatagtagtggttctaccatatactacgcagactgtgaagggccgattcaccatctctagagacaatgcccagaactcactgtttctgcaaatgaacaacctgcgagtcgacgacacggccgtatattactgtgcaaaagaccggacacttcacacacccgctcagatgttttactatggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcatctccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14367 JY8QFUQ01AHV9E productive Homsap IGHV3-48*04 F 1039 98.15 212/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14368 JY8QFUQ01BGFM3 No results +14369 JY8QFUQ01A59BK No results +14370 JY8QFUQ01AZYI1 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1002 94.62 211/223 nt 94.17 210/223 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-1*01 F 1 10 7 12 10.7.12 [2.17.38.11] CARHRNSGTYFDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); tgtctctggtggctccatcaacagtagagattactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgGggggcaccttctacaacccgtccctcaagagtcgagtcaccttatccgtagacacgtccaggagccagttctccctgcagctgagctctgtgaccgccgcagacacggctgtttattattgtgcgagacatcgtaactctggaacctactttgacttctggggccggggatccctggtctccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14371 JY8QFUQ01A3PUT productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 692 80.47 173/215 nt 80.0 172/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); tctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaAaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +14372 JY8QFUQ01AJ8R1 productive (see comment) Homsap IGHV4-61*02 F 947 92.31 204/221 nt 91.86 203/221 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD6-13*01 F 2 10 7 19 10.7.19 [1.17.38.11] CAREAPKAAANSYNSYVMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 94 of V-REGION: 'AG' (2 nucleotides at position 191 to 192 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagtggtagttactactggagctggacccggcagcccgccgggaggggcctggagtggattgggcgtgtccataacagtggtagttccaattacaagccctccctcacgagtcgagtcaccatattagtagacacgtccaagaatcagttctccctgaagctgacctctgtAGcaccgccgcagacacggccgtgtattactgtgcgagagaagcgcccaaggcagcagctaattcctacaactcttacgttatggacgtctggggccaagggaccacggtcaccgtcttctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +14373 JY8QFUQ01CRLTG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14374 JY8QFUQ01BPZU7 No results +14375 JY8QFUQ01C0RNL unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 799 86.38 184/213 nt 85.45 182/213 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD5-12*01 F 1 8 7 X 8.7.X [1.16.38.11] CAGEEMRTRDGGWLRNGRL# out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) tctctggtggctccatgactctttattattggagttggatccggcagcccgcagggaagggctggagtggttgggtacatcgatcacgctgggagcgccaagtataacgcctcccttcagagtcgagtcaccatctcagtcgacgcgcccaagaatcagttctctctgaagttgaactctgtgactgctgcggacacggccgtttattactgtgcgggagaagagatgcgaacgcgggacgggggttggctacggaacggacgtctggggcccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +14376 JY8QFUQ01B1QV9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 783 84.79 184/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [1.17.38.11] CTKTRVVLGITFPFYIYGLDVW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacgttcgacaactatgccatgagctgggtccgccaggcaccaggaaaggggctggagtgggtctccagtattagtggtaatggagaaattgtacaccacgcagacgccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtttttgcaaatgaatggagtgagagacgacgacacggccatttactactgtacgaaaacacgcgttgtgttgggaattacatttccgttctatatctatggtctggacgtctggggccaagggaccacggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +14377 JY8QFUQ01B1Q7T productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14378 JY8QFUQ01BI1XN productive Homsap IGHV4-39*03 F (see comment) 911 90.45 199/220 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-14*01 ORF 2 10 7 12 10.7.12 [1.17.38.11] RTREGPYYYGMDVW in-frame + Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgactccatcagtaatactgattactactgggtctggatccgccagaccccagggaagggactggagtggattgggagtatcgatttcagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccatagacacgtccgagaaccggttctccctgaggttgacctctatgaccgccgcagacacggccgtctattaccgtacgagagagggaccctactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14379 JY8QFUQ01B8VAJ unproductive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1073 98.64 218/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 X 10.7.X [1.17.38.11] CARDRGP*QLVQNGI#DYW out-of-frame - stop codons tctctggtggctccatcaacagtggtggttactactggagttggatccgccagcacccagggaagggcctggagtggattgggtacatctattacagtgggagtacctactacaacccgtccctcaagagtcgagttaccatatcagtagacacgtctaagaaccagttctccctgaagctgagctctgtgactgccgcggacacggccgtgtattactgtgcgagagatcgggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14380 JY8QFUQ01BNXAQ No results +14381 JY8QFUQ01C0HUJ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKDPRLSGSMDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); gcctctggaGttcacctttagcatctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcagtggtgctagtacatactactcagactccatcaggggccggttcaccatcaccagagacaattccgagaacacgctttatctgcagatgaacagcctgagagccgacgacacggccgtatatttctgtgcgaaagacccccggctcagtggctcgatggactactggggccggggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14382 JY8QFUQ01CNBKQ productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14383 JY8QFUQ01BKERP productive Homsap IGHV1-58*02 F 930 92.99 199/214 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD3-9*01 F 1 8 8 14 8.8.14 [0.17.38.11] CAAVLAGWGFYYFDFW in-frame - tggattcacctttaaaagttctgctatacagtgggtgcgacaggcccgtggacaacgccttgagtggataggatggaccgccgttggcagcggtaacacagactacgcacagaagttccaggaaagagtcaccattacgagggacatgtccacaagcacagtctacatggagatgatcaacctgggatccgaggacacggccgtgtattactgtgcggcagtcttggccggctggggattctattacttcgatttctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14384 JY8QFUQ01CBGQK No results +14385 JY8QFUQ01CRB7S No results +14386 JY8QFUQ01BW499 No results +14387 JY8QFUQ01BSIE7 No results +14388 JY8QFUQ01AAZ6M productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14389 JY8QFUQ01AXNSW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14390 JY8QFUQ01CALGE productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14391 JY8QFUQ01AKEEE productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14392 JY8QFUQ01A86IT productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 777 85.05 182/214 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARERGSGPPTGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaagaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14393 JY8QFUQ01CGC96 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14394 JY8QFUQ01AN6X4 No results +14395 JY8QFUQ01C5Q4Z productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1003 96.3 208/216 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDVW in-frame + tctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14396 JY8QFUQ01BTN82 No results +14397 JY8QFUQ01B83SF No results +14398 JY8QFUQ01APVYE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14399 JY8QFUQ01B091Q No results +14400 JY8QFUQ01ACLH9 productive Homsap IGHV3-72*01 F 962 92.41 207/224 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD7-27*01 F 1 8 10 10 8.10.10 [1.17.38.11] CVRDPFSSRGHW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gctctggattcatcctcagtgactaccacatggagtgggtccgccaggctccagggaaggggctggagtgggttggccgtagtagaaagaaagctaatagttacagtacagaatatgccgcgtctgtgaaaggcagattctccatttcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaatcgacgacacggccgtgtattattgtgtcagagaccccttctcaagtcggggccactggggccagggaaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +14401 JY8QFUQ01A3L04 productive Homsap IGHV3-74*03 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14402 JY8QFUQ01B2UA1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 877 89.81 194/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame - tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14403 JY8QFUQ01AO0V4 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt +14404 JY8QFUQ01CEMV2 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatcccctgaccagccccaaggtcctcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcgtgcctggtccagggcttcttccccca +14405 JY8QFUQ01DENT6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1085 100.0 218/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14406 JY8QFUQ01ALYS4 No results +14407 JY8QFUQ01BXON5 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*09 F or Homsap IGHV3-30*10 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAREHDTGVATRYFDYW in-frame + cctctggattcgccttcagtctgtatcctatgcactgggtccgccaggctccaggcaagggactagagtgggtggcacttatctcctctgatggaagtgataagttttcctcagactccgtgaagggccgattcgccatctccagagacaattccaagaacacggtctatctacaagtggacagcctgagaactgaggacacggctatgtatttctgtgcgagagagcacgacacgggagtggcgacgaggtattttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14408 JY8QFUQ01CY3UN productive Homsap IGHV4-4*07 F (see comment) 872 89.77 193/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-22*01 F 2 10 7 22 10.7.22 [1.17.38.11] CARERAYDRNGFYYANRHNWLDTW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01CY3UN ; 8 AA in Homsap_IGHV4-4*07) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgcctccatcacatttggcagttactactggaattggatccggcagcccgccgggaagggactggagtgggtaggacgtatctatgcaagtgggaccacccattccaacccctctctcgagactcgagtcatcatgtcactagacacgtccaacaaccagatctccctgaagctgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagagaaagggcctatgatagaaatggcttttactacgcgaaccgccacaactggctggacacctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14409 JY8QFUQ01APTPO No results +14410 JY8QFUQ01CWR1L productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14411 JY8QFUQ01CUTQ0 productive Homsap IGHV3-48*02 F 876 90.19 193/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [0.17.38.11] CARGQKWLQVLRWFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +14412 JY8QFUQ01A3R0S No results +14413 JY8QFUQ01BVXTP productive (see comment) Homsap IGHV3-66*02 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaAagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14414 JY8QFUQ01BXZSI unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CAREKGSGPP#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14415 JY8QFUQ01CMKX8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14416 JY8QFUQ01CE5NY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14417 JY8QFUQ01COVI0 productive Homsap IGHV3-9*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSGGYTHNYFDYW in-frame + ctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagctggaatagtggtagtatagggtatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattactgtgcaaaaggggatagtggtggttatacccacaactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14418 JY8QFUQ01ACV8E No results +14419 JY8QFUQ01AFYS4 unknown (see comment) Homsap IGHV3-11*01 F (see comment) 756 83.41 181/217 nt 82.49 179/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); ctctggattcaccctcagtgactacagtatgagttgggtccgccaggctccagggaaGggggctggagtgggtctcatacatcagccgaagtggaagtaatgtggaaactgcggactctgtgaGggggccgattcaccgcctccagggacaccgccaataattcactgtttctgcggatgaatagcctgacagtcgaggacacggccctctattactgtgcgagagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14420 JY8QFUQ01B2GHU productive (see comment) Homsap IGHV4-61*02 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARDTGQTYGRGPLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtgcctccataaataggggtaattattactGggaactggatccggcagcccgccggggaaggcctggaatggattggccgaatctatacaagtgggagcaccatctacaacccctccctcgggggtcgagtcaccatgactgtagacccgtccgagaatcagttcttcctgagactgagttctgtgaccgccgcagacacggccgtttatttttgtgcgagagacactggacaaacctacggtcggggccctttggactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14421 JY8QFUQ01AITAG No results +14422 JY8QFUQ01BPN9H productive (see comment) Homsap IGHV3-7*02 F 909 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaagGggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14423 JY8QFUQ01A8ROM No results +14424 JY8QFUQ01BNUQT productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14425 JY8QFUQ01AZVG9 unproductive (see comment) Homsap IGHV4-61*02 F (see comment) 714 80.27 179/223 nt 79.82 178/223 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [2.17.38.11] CARERGASIGEAGGLDSW in-frame - stop codons Low V-REGION identity (80,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'CC' (2 nucleotides at position 33 to 34 in the user submitted sequence), (cause frameshift); tctcttgggtggccccgtcaacaaatggtgatCCagtattggagctggatccggcagcccgccgggaaggggctggagtggatcggacgtgtttctgctagtgggacctacagctacaatccctccctcaggagtcggatcaccatctcaatagacatgtctaagaatcacttctccctgaggttgatttctgtgacggccgcagacacggccttatattattgtgcgagagagcgtggtgcgtcgattggcgaagcgggaggccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14426 JY8QFUQ01AQPZZ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 7 8 13 7.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) tctggattcagcttagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14427 JY8QFUQ01CW489 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 7 22 8.7.22 [1.17.38.11] CARVKTDYYDSSGSYLPLYFFDYW in-frame - tctctggtgactccttcagaactcactactggagttggattcgacagcccccggggaggagattggaatggattggcaatatatattatattgggaccaccaactacaacccctccctcaagagtcgagtcaccatgttagtggacacgtccaagaagcagttctccctgagactgagttctgtgaccgctgcggacacggccatgtattattgtgcgagggtcaagactgattattatgatagtagtggttcttacctgcccctgtatttctttgattactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14428 JY8QFUQ01DAG7H productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame - cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14429 JY8QFUQ01CNNQZ productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 832 87.5 189/216 nt 86.57 187/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-6*01 F 1 8 7 12 8.7.12 [1.17.38.11] CVRSYSRTSEFDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattcagtttcagtaccTtttggcatgagttggatccgccagacgccaggcaaggggctggagtgggtgacagttatatggtcggatggaactaaaaaaattatgcagactccgtgaagggccgattcaccatctccagagacaatgtcaagaacacggtttatctgcagatgagcagcctgagagtcgaggacacgggcgtatattattgtgtgaggtcgtatagtaggacatctgagtttgactactggggcccgggaacccaagtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14430 JY8QFUQ01BBZNJ productive Homsap IGHV3-7*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame - cctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +14431 JY8QFUQ01A9SHR productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14432 JY8QFUQ01C2BMN productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctccggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14433 JY8QFUQ01BF7UR unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 118 50.72 106/209 nt 8 8 X 8.8.X [1.17.35.X] null + No rearrangement found ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14434 JY8QFUQ01AN0QQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-17*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKEMIRYGDDVFGGLNVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggatttacctttagcagttatgccatgaactgggtccgccaggctccagggaaggggctgcagtgggtctctggtattagtggtggtggtgatgacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtgtattactgtgcgaaagaaatgatccgctacggggacgacgtttttggcggtctgaacgtctggggccaagggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +14435 JY8QFUQ01APJMN productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 841 87.96 190/216 nt 87.5 189/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSGPSGYARYESMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 94 of V-REGION: 'T' (1 nucleotides at position 186 to 186 in the user submitted sequence), (cause frameshift); tctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacctTgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14436 JY8QFUQ01C4QN4 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14437 JY8QFUQ01DBWS0 unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1085 100.0 218/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKVGSTVVG##FDYW out-of-frame + stop codons cctctggattcaccttcagtagctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgaaagtagggtcgacggtggtagggggactttgactactggggccagggaacccgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14438 JY8QFUQ01C2I1T unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 876 90.19 193/214 nt 89.72 192/214 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD6-19*01 F 2 8 7 X 8.7.X [1.17.38.11] CMNELGYCSGR## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcagtgatagttacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcgattatttataCggggaggtaccacatattatgccgactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtcggggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14439 JY8QFUQ01BV0EO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14440 JY8QFUQ01DL9WP productive (see comment) Homsap IGHV3-11*01 F 984 95.79 205/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD1-1*01 F 3 8 8 13 8.8.13 [1.17.37.11] CARVNTWNADYFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 3 nucleotides (from position 104 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcagtgactactacatgatctggatccgccaggctccagggaaggggctggagtgggtttcatacattactagtcgtggtactatcatgtacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggccatttattactgtgcgagagtgaacacatggaacgccgactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14441 JY8QFUQ01C5ERR No results +14442 JY8QFUQ01AW1YP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14443 JY8QFUQ01CBK2S No results +14444 JY8QFUQ01BW9YU productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAREGVGGFDYW in-frame + cctctggattcacctttagtagctattggataagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaagcaagatgggagtaaggtggagtatgtgggctctgtgaagggccgattcaccatctccagagataatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtttattactgtgcgagagagggggtgggaggatttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14445 JY8QFUQ01AQW3Z productive Homsap IGHV3-9*01 F 837 87.56 190/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaactttgatggtcatgccatgcactgggtccggcaagttccagggaagggcctagagtgggtcgcaggtattaagtcgaatggtgatgtccttggttctgtggactctgtgaagggccgaatcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14446 JY8QFUQ01BYZ7Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcagttccccgaaccggtgacggtcgtgcgtggaactca +14447 JY8QFUQ01DBJH1 unproductive (see comment) Homsap IGHV4-61*02 F 893 89.59 198/221 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 10 7 X 10.7.X [1.17.38.11] CARQGG**WTLE*LL# out-of-frame + stop codons tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaagggggatagtagtggaccctggaatgactactgggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14448 JY8QFUQ01A4EKY unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 X 8.7.X [1.17.38.11] CAKTTMTSVT#DWFDPW out-of-frame + in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactgggggcaccgactccaaccCcctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +14449 JY8QFUQ01BV6AQ productive (see comment) Homsap IGHV4-4*07 F, or Homsap IGHV4-61*02 F 701 92.59 150/162 nt 91.98 149/162 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 X 7 12 X.7.12 [X.9.38.11] CARGSGSGSYSNLW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); gggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccCctgaagntgcgctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14450 JY8QFUQ01CX24P productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14451 JY8QFUQ01DPGMR No results +14452 JY8QFUQ01AIO4V productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt 83.41 181/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.16.38.11] CARDSALFGYARYDAMDAW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 38 in the user submitted sequence), (cause frameshift) cctctggatccagtttcagtggttttggcgtgaactggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaaggggccccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14453 JY8QFUQ01C1WUD unproductive Homsap IGHV3-30*07 F 863 89.3 192/215 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD5-12*01 F 2 8 8 X 8.8.X [0.17.38.11] CGKQLGAHKGADY## out-of-frame - ctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccggttcaccatctccagagacaactccatgaacacactgtatctgcaaatgaacagcctgggaaccgatgacacggccttatattactgtggaaagcaattgggggcccataaaggggctgactactggggccagggggaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14454 JY8QFUQ01AT7QO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame - Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14455 JY8QFUQ01APZQG productive (see comment) Homsap IGHV1-3*01 F 894 91.12 195/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [0.17.38.11] CAKDKWYYDSSGYQYYLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); tggatacagcttcactaactacaatatccattgggtgcgccaGggcccccggacaaaGggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattactgtgcgaaagacaaatggtactatgatagtagtggttatcaatactaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14456 JY8QFUQ01AG43S No results +14457 JY8QFUQ01AHEWI productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 998 94.2 211/224 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcgaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14458 JY8QFUQ01DVC4K productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14459 JY8QFUQ01A61WO productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame - cctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +14460 JY8QFUQ01BVNEI productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 930 92.99 199/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-25*01 F 1 8 8 15 8.8.15 [0.17.38.11] CARHEGYNSRYYYFGYW in-frame + tggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14461 JY8QFUQ01BJSH2 productive (see comment) Homsap IGHV3-9*02 F 923 91.74 200/218 nt 90.83 198/218 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 7 11 8.7.11 [2.17.38.11] CGKDMRPGGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 92 in the user submitted sequence), (cause frameshift) gcctccggattcacctctGgaaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14462 JY8QFUQ01A4MG4 No results +14463 JY8QFUQ01BOQ3Q productive (see comment) Homsap IGHV3-33*05 F (see comment) 761 83.49 182/218 nt 83.03 181/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); cgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaaaGatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +14464 JY8QFUQ01DWDGD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + cctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttc +14465 JY8QFUQ01C9QGG productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 894 91.12 195/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-1*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARRQLALAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); tggatacacctttatcacctactggatcgcctgggtgcgccaaatgcccgggaaAaggcctggagttgatgggagtcatctatcctggtgactctgagaccagatCacagcccgtccttccaaggccacatcaccctctcagtcgacaagtccatcgataccgcctacctggagtggagcagcctgaaggcctcggacaccgccatgtacttctgtgcaagaagacaactggcccttgcctactggggccagggaacccaggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14466 JY8QFUQ01AHCVV No results +14467 JY8QFUQ01CISTZ No results +14468 JY8QFUQ01AT4EU productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD2-8*02 F 2 8 8 24 8.8.24 [1.17.38.11] CVRAAGYCPGGDDCYKIGTHDSLDIW in-frame + gtctggattcaccttcagtacctatggcacacattgggtccgccaggctccaggcaaggggctggactgggtggcagttagttggcatgatggaagtcaggaatattatgcagactccgtgaggggccgattcactgtctccagagacaattccaagaacacggcatatctgcatatgaatgtcctgagaggcgaagacacggctgtctactactgtgtgagagcggcggggtactgtcctggtggtgatgactgctacaagatcggaactcatgactcccttgatatctggggccgaggggcagttgtctccgtctcctctgcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +14469 JY8QFUQ01AYI64 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaacctcag +14470 JY8QFUQ01DQPOL productive Homsap IGHV3-30-3*01 F, or Homsap IGHV3-30-3*02 F (see comment) 411 80.0 104/130 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 X 5 18 X.5.18 [X.X.38.11] CARDDFYSSGNYGGFGMDVW in-frame + Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtcactatgactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14471 JY8QFUQ01C82Q0 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 797 85.32 186/218 nt 83.94 183/218 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSGSSEYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'TGG' (3 nucleotides at position 28 to 30 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'TA' (2 nucleotides at position 36 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); cctctggattcagcgttaagttcgttaTGGgcatgTAactggggtccgccaggctccatggggggggctggGagtgggtctcattcattaacagtattagtagttataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14472 JY8QFUQ01B8D2N productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcaccttcatcagttatggcatgagttgggtccgccagtttccagggaaggGggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14473 JY8QFUQ01CCMNU productive Homsap IGHV4-4*07 F, or Homsap IGHV4-59*10 F 800 86.05 185/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAREAPDGSVTYDYW in-frame + tctctagtggctccatcaatggtcactactgggcctggatccggcagcccgccgggaaggggctggagtggatggggcgcatctatgcaactggggtcaacaactacaatccctccctcaggagtcgagtcaccatgtcagtagacacgtccaacaaccgtctcttcctgagcttgacctctgttaccgccgcggacacggccatatattattgtgcgagagaggcccccgatggttcggtgacttatgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +14474 JY8QFUQ01BBKZT productive Homsap IGHV3-7*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame - cctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14475 JY8QFUQ01B888I productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 706 81.02 175/216 nt 79.63 172/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [2.17.38.11] CARLDGHFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'C' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); gtctctgggttcaccatcagtCacgtactccatgggCctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgGcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14476 JY8QFUQ01DJMF5 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 883 89.5 196/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARKRVPGGTFYGDYW in-frame - gcctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14477 JY8QFUQ01BKGRR No results +14478 JY8QFUQ01APZAB productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1040 97.71 213/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame + cgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +14479 JY8QFUQ01BBDS8 productive (see comment) Homsap IGHV4-39*02 F 801 91.58 174/190 nt 91.05 173/190 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.6.38.11] CARIVVRQFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 43 of V-REGION: 31 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tctctggtgactccatttccagtactagttattactgggggctgattcggggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14480 JY8QFUQ01C8V0W productive (see comment) Homsap IGHV3-9*01 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 67 of V-REGION: 'G' (1 nucleotides at position 108 to 108 in the user submitted sequence), (cause frameshift); cctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggcGtatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14481 JY8QFUQ01C0HLW productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaAGggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14482 JY8QFUQ01BCBTW No results +14483 JY8QFUQ01DHPUD No results +14484 JY8QFUQ01AL0O1 productive (see comment) Homsap IGHV3-7*01 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [2.17.38.11] CAREQSSRGYPLDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); gcctctggattcacctttgagacttattggttgacctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaAagcaagatggaagtgagacatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaggaactcactgtttctgcaaatgaacagcctgagaggcgacgacacggctgtctattactgtgcgagagaacaatcctcgaggggatacccacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14485 JY8QFUQ01CLM87 No results +14486 JY8QFUQ01ADGL2 productive Homsap IGHV3-7*01 F 896 90.37 197/218 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [1.17.38.11] CARVIPGRGNYAFDVW in-frame - cctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14487 JY8QFUQ01AF8I8 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 935 91.07 204/224 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [1.17.38.11] CTTAPSETYATEYFAMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14488 JY8QFUQ01A8JNL productive (see comment) Homsap IGHV2-5*02 F 1071 93.44 228/244 nt 93.03 227/244 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 3 10 7 13 10.7.13 [9.17.38.11] CAHRRVGTATAFDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttctctgggttctcactcagtaacagtggagtgggtgtgggctgggtccgtcagcccccaggaaaggccctggagtggcttggacacaCttttttgggatgatgataagcgctacagtccctctctgaaaagcaggctcaccctcaccaaggatacctccaaagaccaggtggtccttgaaatgaccaacatggaccctgtggacacagccacttattactgtgctcacagacgtgtggggactgcgaccgcttttgatttctggggccaggggacaacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14489 JY8QFUQ01AF5K9 productive Homsap IGHV1-3*01 F 966 94.86 203/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARWNNDLDYW in-frame - tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14490 JY8QFUQ01B59TP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1075 100.0 216/216 nt 99.07 214/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.16.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccGtttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14491 JY8QFUQ01BZB16 productive Homsap IGHV3-7*01 F 1026 97.24 211/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccttgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14492 JY8QFUQ01A1MAL productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 857 87.78 194/221 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 10 7 20 10.7.20 [1.17.38.11] CAATMNYMSADSTGWYGGGDYW in-frame - tctctggtggctccatcaataataggctctactactggggctggattcgtcagcccccagggaagggtctggagtggattgggagcatccataatagtgggagcacctactacagtccgtccctcgagagtcgtgtcatcatctccgtagacacgtccaacaagcggttcttcctgaggctgagctctgtgaccgccgcagacacagctatgtactactgtgcggcaacgatgaattacatgtccgccgatagcactggctggtacggcgggggtgactactggggccagggagcctcggtcaccgtgtcctcagtatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14493 JY8QFUQ01BO2JV productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame + ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgtctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag +14494 JY8QFUQ01CE5WC unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CTKRLSGRPLVESGAP#FFDDW out-of-frame + stop codons cctctggattcacctttagcgactatggcatgagttgggtccgccaggctccagggaagggactggagtgggtctcaagtattatcgctaatggtggtgacacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagatgaacagccttagaggcgaggacacggccgtatattattgtacgaaaagactatccggacggccgcttgttgaatcaggtgcgccccttctttgacgactgggaccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14495 JY8QFUQ01AVR4A productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcacctcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14496 JY8QFUQ01C2ENZ No results +14497 JY8QFUQ01AQCN4 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 990 95.39 207/217 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD6-13*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDRYTDSWFNGNWFAPW in-frame + ctctggattcacatttgatgaatatggcatgagctgggtccgccaatctccagggaaggggctggagtgggtctctggtattaattggaatggtgccagcataggttatgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtttctgcaaatgaacagtctgagagccgaagacacggccttgtactactgtgtgagagacaggtataccgacagttggtttaatggaaactggttcgccccctggggccagggaacccaagtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14498 JY8QFUQ01AZMVL unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 836 87.91 189/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD2-21*02 F 1 8 7 X 8.7.X [1.17.38.11] CARGRTVVTVIDYIDY## out-of-frame + in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctgggggActccattagtggttactattggacgtggatccggcagAcccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggttcagggagccctggtcagcgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagactgggaacgtggtgtcgccatgcctggctccagggcttcttccccca +14499 JY8QFUQ01AMFYO productive (see comment) Homsap IGHV3-48*01 F (see comment) 764 84.19 181/215 nt 83.72 180/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccctaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14500 JY8QFUQ01ASQGX productive (see comment) Homsap IGHV3-11*01 F 872 89.77 193/215 nt 88.37 190/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcaccctcagtgactactacatgagttggttccgccaGggctccagggaaggGggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcatgcctggtccagggcttcttccccca +14501 JY8QFUQ01AU02Q productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 857 87.78 194/221 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD1-1*01 F 1 10 7 14 10.7.14 [1.17.38.11] CARELGNTERGIVDPW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcagcgacactagttatcactgggcctggatgcgccagcccccagggaagggcctggagtggattgctaatgttcattatactggcagcgcccactacaacccgtccctcaagagtcgagtcaccatactagtagacacgtcccagaatcagttctccctgatgctgagttctgtgaccgccacagacacggctgtgtattactgtgcgagggaacttggtaatactgagaggggaatcgtcgacccctggggccagggaatcccggtcagcgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14502 JY8QFUQ01CJOHM productive Homsap IGHV3-7*01 F 977 94.5 206/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDGYYYYHSGMDVW in-frame - cctctggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattattgtgcgaaagacggctattattattatcacagcggtatggacgtctggggccaagggaccacggtcatcgtctcccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14503 JY8QFUQ01ANAJP productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14504 JY8QFUQ01AJQN5 productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame - cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14505 JY8QFUQ01DMPOP unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 905 90.83 198/218 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRHTAMERGDY## out-of-frame + gttctggatatgactttatcaactactggatcggctgggtgcgccagatgcccgggagaggcctggaatggatgggaatcatctttcctgatgactctgatgccagatatagtccgtccttccagggccacgtcaccatctcagccgacaagtccacaagcaccgcctacctggagtggagcagcctgaaggcctcggacaccgccatctactactgtgtgagacatacagctatggagaggggtgactactggggccccgggaaccctggtcaccgtcacctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +14506 JY8QFUQ01BKQBZ productive Homsap IGHV3-48*02 F (see comment) 724 81.48 176/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14507 JY8QFUQ01DQV9H productive (see comment) Homsap IGHV3-11*01 F 890 90.7 195/215 nt 89.3 192/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'CG' (2 nucleotides at position 71 to 72 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) ctctggaattcagcttcagtgactactacatgagtTtgggtccgccaggctccagggaagggactggagtCGggatttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14508 JY8QFUQ01CHPCA productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccacaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +14509 JY8QFUQ01A0ZX6 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame + ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag +14510 JY8QFUQ01AMOBY unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD2-8*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDRGCGNGACHVADY## out-of-frame + cctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +14511 JY8QFUQ01B8ACY unproductive Homsap IGHV3-48*02 F 896 90.37 197/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARGQNGYKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14512 JY8QFUQ01AS6B9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-8*02 F 2 8 8 20 8.8.20 [1.17.38.11] CARDLWLCSGGECYHRGGFENW in-frame + ctctgggttcaccttcagtaactcctggatgcactgggtccgccaagctccagggaaggggccggagtgggtctcacgtattaatagtgatgggagtaatacaatctacgcggactccgtgaagggccgactcaccatctccagagacaacgccaaaaacacggtgtatctgcaattgaacagtctgagagccgaggacacggctgtgtactactgtgcaagagatctgtggctttgtagtggtggtgaatgctatcatcggggtggttttgagaactggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +14513 JY8QFUQ01B3JZW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 873 88.99 194/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame - cctctggattctccgtcagtaattactggatgcactgggtccnccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagattactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +14514 JY8QFUQ01BK5EM productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + ctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgccctggtccagggcttcttccc +14515 JY8QFUQ01C3WVN No results +14516 JY8QFUQ01AITB3 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 6 10 9.6.10 [1.17.38.11] CASHGGKYFPQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggacaaatccatcatgtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14517 JY8QFUQ01DA9DR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKKHYNSGTYLYNFDYW in-frame + ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaaagcattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +14518 JY8QFUQ01AXCM5 productive Homsap IGHV4-4*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [1.17.38.11] CARGKDYYDTTGSLEDGFDIW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctctggtggctccataagaagttactattggagttggatacggcactccgccgggaagggactggagtggatcgggcgcatatatgacagtggtagtacaaactacaatccctccctcaagagtcgagtcagcatgtcagtggacacgtccaagaaccaggtctccctgaagttgatctctgtgaccgccgcggacacggccatgtattattgtgcgagagggaaggattactatgatacaactggctccctcgaggatggttttgatatttggggccaagggacgatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14519 JY8QFUQ01AS8ER No results +14520 JY8QFUQ01BZ0SZ No results +14521 JY8QFUQ01APBH8 No results +14522 JY8QFUQ01BDTVE No results +14523 JY8QFUQ01AJL9X No results +14524 JY8QFUQ01B75FJ unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDNYGDYW# out-of-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa +14525 JY8QFUQ01CEZA3 productive (see comment) Homsap IGHV3-9*01 F 937 92.24 202/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [2.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); gcctctggattcaccGtttcatgattataccatgGcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14526 JY8QFUQ01AAXKV productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14527 JY8QFUQ01A6MYW productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1033 96.4 214/222 nt 95.5 212/222 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 7 10 17 7.10.17 [1.17.38.11] CTRDNPPLRSLEWLPFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift) ttctggatcacctttggtgattaGtagtatgagttggttccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcaaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14528 JY8QFUQ01BXKGT productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 725 81.65 178/218 nt 81.19 177/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDQYGSPSDFDNW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'GGA' (3 nucleotides at position 84 to 86 in the user submitted sequence), (do not cause frameshift); cctcagggttcgtttttgagaaatacgccatgagttgggtccgccaggctcccggaaaggggctggagtgggtctcggctattGGAggtgttgatgatgttggcacatactacgcagcctccgtgaagggtcggttcaccatatccagagacgattccagggagattctctatctacaaatgagtaacctgagagtcgacgatacggccgtctattactgtgcgaaagatcaatatgggagcccatccgactttgacaactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14529 JY8QFUQ01DLJI4 unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 92.86 208/224 nt 91.52 205/224 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD1-14*01 ORF 1 8 7 X 8.7.X [4.17.38.11] CARGDPIFM#*C out-of-frame + in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); cctctgcagcctctggattcattgtcaatagcaactacatgagttggGgtccgccaggctccagggaaggggntGggactgcgtctcagttatttatcccggtgGgtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggaccccattttcatgatagtgttaaaggggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14530 JY8QFUQ01CZ5KL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ5*02 F (see comment) 237 96.08 49/51 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDAALLAAAGDNWFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcacatttgacgactacggcatgagttgggtccgccaggctccagggaaggggctggagtgggtctcccttattagtggtggtggtggcagcacatactatccagactccgtgaagGggtcggttcatcgtctccagagacaattccaagaacatgttgtttcttcaaataaacaacctgaaaatcgaagacacggccgtttatttttgtgcgaaggacgcggcccttctagcagctgccggggacaactggttcgacacctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14531 JY8QFUQ01AG5LX productive (see comment) Homsap IGHV3-74*03 F (see comment) 702 80.65 175/217 nt 80.18 174/217 nt Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRGTTGWRGVDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcaacgtcagtggatactggatgcactGgggtccgccaagtgccagggaaggggctggtatgggtctctaggctttcggatgatgaaattactataacttacgcggactttgtggagggccgattcaccatctccagagacaacgccaggaacgaggtctatctgcaaatgaatgatttgagagtcgacgatacggctgtatacttttgtgtgaggggaaccactggctggaggggggttgactactggggccaaggcgccctcgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14532 JY8QFUQ01DJ04F unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSGFLLDG#YW out-of-frame - ctctggattcagctttagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaaatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtttttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtgggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14533 JY8QFUQ01C4SH0 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattCaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14534 JY8QFUQ01CGSSK unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CAREKRFGPPH#GMDVW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14535 JY8QFUQ01AROP7 productive (see comment) Homsap IGHV3-66*02 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-21*01 F 3 8 7 11 8.7.11 [1.17.38.11] CARHLMVYALDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift); tctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaggggctggagtgggtctcagtcttatttagtactggcactgcatactacgcagactccgtgAaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14536 JY8QFUQ01DHU9P productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 786 85.51 183/214 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDHFDSW in-frame + Other possibilities: Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggatacaccttcaccgactacttcatacactggctgcgactggcccctgaacaacgacttgagtggatgggatggatcaaccctaagaatggtgacacaaattatgcacggaactttcagggccgggtcaccatgacccgcgacacgtccgtcagaacagtatatgtggaggtgaacagcctgaaatctgacgacacagccatttattactgtgcgcgaggcttttatggtgaccactttgactcctggggccagggagccgtggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14537 JY8QFUQ01AHUWU No results +14538 JY8QFUQ01DPATU unproductive Homsap IGHV3-7*01 F 1005 95.45 210/220 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [2.17.38.11] CAISSDFYSTGYW# out-of-frame - agcctctggattcagctttagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaaatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtttttgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgattagtagtgatttttactcgacgggctactgggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14539 JY8QFUQ01AYIXT unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14540 JY8QFUQ01BYPF6 No results +14541 JY8QFUQ01CE1SQ unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14542 JY8QFUQ01C546L productive Homsap IGHV3-30*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDELPWDTIEYYFDYW in-frame + ctctggattcaccttcaatacctattctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14543 JY8QFUQ01CKAX8 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1054 96.05 219/228 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [2.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tctaccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14544 JY8QFUQ01CV905 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1047 99.07 212/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + ctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14545 JY8QFUQ01BH736 No results +14546 JY8QFUQ01AN6BM productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ3*02 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDIW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacatctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaaggactacttccccgaaccggtgacggtgtcgtggaactc +14547 JY8QFUQ01CXANI productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +14548 JY8QFUQ01AO0LA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14549 JY8QFUQ01CJ9DH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CARAYSGPGPYYFDYW in-frame + ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +14550 JY8QFUQ01DPDZW productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt 85.58 184/215 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD5-24*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CATLRGVLSTSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaggagttattattggagttggatccggcagCcccccaggaaagggactggagtggattggttatattaattatgttgggggAcaccgattacaaccCcctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagaggggtactttcgactagctggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgccctggtcaaggactacttcccccgaaccggctgacggtgtcgtggaactcag +14551 JY8QFUQ01C9BZF unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F (see comment) 562 73.15 158/216 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt Homsap IGHD5-18*01 F 3 8 8 X 8.8.X [1.17.38.6] PV## out-of-frame - Low V-REGION identity (73,15% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14552 JY8QFUQ01BR8PW No results +14553 JY8QFUQ01CHOA5 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14554 JY8QFUQ01CXLRG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt Homsap IGHJ2*01 F (see comment) 94 64.15 34/53 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [2.17.38.11] CARGHSYYVSSGPDYW# out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) agcctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactgggggccacggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14555 JY8QFUQ01BLZ8Q productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 928 91.78 201/219 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKAGRGLIRPNNWFDPW in-frame - gcctctggatttaccttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcggggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14556 JY8QFUQ01DMCYI productive (see comment) Homsap IGHV1-18*01 F 876 90.19 193/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 8 8 8 8.8.8 [0.17.38.11] CARDRPNEFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); tggttacccctttaatacctatggtatcacctgggtgcgacaggcccctggacacggccttgagtggatggGggtggatcagcgttcacgatggcaacacaaactatgcacagaatctccagggcagagtcaccctgaccacagacacatctacgagcacagcctacatggaactgaggggtctcagatctgacgacacggccgtttattattgtgcgagagatcgcccgaatgaattctggggccagggaaccctggtcaccgtcttctcagcatccccgaccagccccgaaggtcttcccgctgagcctctgcagcacccagccagatgggaattggtcatcgcctgcctggtccagggcttctc +14557 JY8QFUQ01BJRSQ No results +14558 JY8QFUQ01CVGIT productive Homsap IGHV3-9*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + ctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaattc +14559 JY8QFUQ01CIDLV productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 966 92.83 207/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaagacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14560 JY8QFUQ01BGL40 productive Homsap IGHV4-39*03 F 939 91.44 203/222 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [2.17.38.11] CARSITLTVVVMNDAFDVW in-frame - tgtctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14561 JY8QFUQ01DD88M productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14562 JY8QFUQ01CEH6F unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt +14563 JY8QFUQ01APM60 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 1034 98.14 211/215 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-2*02 F 2 8 7 15 8.7.15 [1.17.38.11] CARGVGVSWHTEYFQHW in-frame + cctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagaggggtcggcgtcagctggcatactgaatacttccagcactggggccagggcaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag +14564 JY8QFUQ01ANF78 unproductive (see comment) Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDWSSMVRGSF##DHW out-of-frame - stop codons gctctggattcaccttaagtagccatcagatgagctgggtccgccaggctccagggaaggggctggagtgggtggctaagataatccaagatggaagtgagacatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatggacagcctgagagtcgaggacacggctgtgtattactgtgcgagagattggtcctctatggttcgggggagtttcaattgaccactggggccagggaaccctgcttaccgtctcctcggcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14565 JY8QFUQ01ADGA2 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 841 87.96 190/216 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD3-3*01 F 1 8 8 X 8.8.X [1.17.38.11] CARILTLFAVVTSSGMDV#W out-of-frame + tctggatttaccttcagtaattatgacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatcaccagtagtggtagttatgtctaccattcagactcaacgaagggccgattcaccatctccagagacaacgcccagaattcactatttctgcaaatgaacaacctgagacccgaggacacggctatatattactgtgcgaggatcctgacgctttttgcagtggttacctccagtgggatggacgtcttggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccacgccagatgggaacgtggtcgtcgcatgcctggtccagggcttgcttcccccag +14566 JY8QFUQ01AH38B productive (see comment) Homsap IGHV4-61*02 F 806 85.78 187/218 nt 85.32 186/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 10 6 16 10.6.16 [1.17.38.11] CAIERSRSIGGDGQFDFW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 102 in the user submitted sequence), (do not cause frameshift) tttctggtggccccatcagaggcggtggtttctactggacctggctccggcagtccgccgggaagggcctggagtggatcggacgtatttatgacagtggcagtgactacaatccttctctcaagagtcgagtcaccatgtcagtagacacgtccaagagccagttctccctgaggctgagttctgtggccgccgcagacacggccgtttacttctgtgcgatagaacgtagtagatcgattggcggagacggacaatttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +14567 JY8QFUQ01B38ZE productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgagggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14568 JY8QFUQ01DT6Z6 unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 975 95.33 204/214 nt 94.39 202/214 nt 8 8 X 8.8.X [0.17.38.X] null - No rearrangement found in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 209 to 209 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagctactatatacactgggtgcgacaggCcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtttaCtttttgtgcgagagacggatattgtagtacgaagaattgcttcgccaagaccgacttcgtttgggggaccataaactactggggccagggatgccctggtcgccgtctcttcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgctcgtgcaggcgttcttccccca +14569 JY8QFUQ01CATUZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 974 95.75 203/212 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 7 8 14 7.8.14 [X.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14570 JY8QFUQ01DN11O productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +14571 JY8QFUQ01CM5PB productive (see comment) Homsap IGHV3-7*03 F (see comment) 789 84.55 186/220 nt 84.09 185/220 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); agcctctggattcagttttagtGaccttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14572 JY8QFUQ01A9CIV productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 964 93.61 205/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gcctctggattcacCctttggttattatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14573 JY8QFUQ01CXVCW productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14574 JY8QFUQ01C3YHE productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14575 JY8QFUQ01AVLD8 productive (see comment) Homsap IGHV3-7*01 F 928 91.78 201/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'T' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); gcctctggcttcacctttgaaaattatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaTggggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14576 JY8QFUQ01CP1MJ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame + ctctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +14577 JY8QFUQ01CGJJT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1014 95.91 211/220 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) agcctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14578 JY8QFUQ01ALEYX productive Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + cctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccctag +14579 JY8QFUQ01CGNIA productive (see comment) Homsap IGHV4-39*02 F 952 91.89 204/222 nt 91.44 203/222 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [2.16.38.11] CARRYSWNYERFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tgtctctggtgactccatcagtactaataattactactgggcctggatccgccagccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14580 JY8QFUQ01CSL9Y unknown (see comment) Homsap IGHV3-74*03 F 104 52.94 72/136 nt 8 7 X 8.7.X [2.17.11.X] null + No rearrangement found stop codons gcctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14581 JY8QFUQ01CK5TA productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARDRRPLREFDCW in-frame + ctctggattcaccctctccagctatgctatgcactgggtccgccagtctcccggcaaggggctagagtgggtggcagctatttcatatgatggaagtaaaatatattacgcagactccgtgaggggccgcttctccatctccagagacagttccaagaacactctgcatttgcaaatggacagcctgagacctgaggacacggctacatattactgtgcgagagatagacggccacttagggagtttgactgttggggccagggaaccccggtcgccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggctt +14582 JY8QFUQ01DNLDV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATSRGSANWYPFDHW in-frame - cctttggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14583 JY8QFUQ01AFD8Q No results +14584 JY8QFUQ01BF9SP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 824 86.7 189/218 nt 86.24 188/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); cgtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgGggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14585 JY8QFUQ01B8IVO No results +14586 JY8QFUQ01APYJS productive Homsap IGHV3-11*01 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD1-26*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARDGDDYRSYYYGMDVW in-frame + ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcatggtatacctggcagactctgtgaagggccgattcatcatctccagggacaacggcgagaactcactgtatcttcaaatgaacagcctgagagccgaagacacggccgtgtattactgtgcgagagatggggacgactacaggtcgtactactatggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14587 JY8QFUQ01BU3VU productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 868 89.35 193/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame + tctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +14588 JY8QFUQ01B36OI unproductive Homsap IGHV3-11*01 F 972 94.47 205/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARRRDYGDYGDGFDYW# out-of-frame + ctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactgggggccaaaggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +14589 JY8QFUQ01BIP32 unproductive Homsap IGHV3-9*01 F 1004 95.87 209/218 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKWGRALVRGLIPVQLVR#PW out-of-frame + cctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggcaacataggctatgcggactctgttaagggccgattcaccatctccagagacaacgacaagaactccctgtatctgcaaatgaacagtctaagacgtgaggacacggccttctattactgtgcaaaatgggggagggctttggttcggggacttatcccagtacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14590 JY8QFUQ01C1H8N No results +14591 JY8QFUQ01B7XXQ productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 922 90.22 203/225 nt 89.78 202/225 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD5-24*01 ORF 3 8 10 17 8.10.17 [2.17.38.11] CSRGLGDGYNLGYHALDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); gcttctggattcagttttggtgattattctatgatctggttccgccaggcaccggGggaaggggctggagtgcgtaggtttcattagaagcagagcatatggtgggacaacacaatacgccgcgtctgtgaaagacagattcaccatctcaagagatgatcccaaaggcatcgcctatttgcaaatgagcagtctgaaagtcgacgacacaggcgtgtatttttgtagtcggggattaggcgatggctacaatctgggttatcatgcccttgatatctggggccaagggacaatggtcaccgtctcttcagcatcccccgaccagccccaaggtcttcccgctgagccctcgacagcaccccccaagatgggaacgtggtcgtcgccatgcctggctccagggcttcttccc +14592 JY8QFUQ01C65WZ unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame + ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +14593 JY8QFUQ01ADY7Y No results +14594 JY8QFUQ01BIUEK productive Homsap IGHV3-66*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 7 13 8.7.13 [2.17.38.11] CASRVAARQGYFDNW in-frame - agcctctggattcaccgtcggtagtaattacatgaactggatccgccaggctccagggaaggggctggagtggatctcagttatttataccggtggtagtacatactacgtggactccgtgaggggccgattcaccatctccagagacaattccaagaacacgctgtatcttcaaatgaacagcctgagagctgaagacacggctgtgtattactgtgcgagccgtgtagcagctcgtcagggctactttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14595 JY8QFUQ01DD8IM No results +14596 JY8QFUQ01ACYZU No results +14597 JY8QFUQ01CE7GX productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1071 99.54 216/217 nt 98.62 214/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.16.38.11] CARDFFIGGYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcacgttcagtagctatagcatgaactggGgtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14598 JY8QFUQ01DMUKG productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14599 JY8QFUQ01C8GQ3 productive (see comment) Homsap IGHV3-23*05 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagctccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +14600 JY8QFUQ01AUHXT No results +14601 JY8QFUQ01DHIV6 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 976 94.91 205/216 nt 93.98 203/216 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.16.38.11] CARDTLEVVSNMDDAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 49 of V-REGION: 2 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) cctctggattcatcttcagtcgttGatagcatgaactgggtccgccaggctccagggaagggctgagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14602 JY8QFUQ01BUUWC productive (see comment) Homsap IGHV3-49*04 F (see comment) 809 84.82 190/224 nt 83.93 188/224 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD3-3*01 F 2 8 10 16 8.10.16 [1.17.38.11] CARDRDYHDSWPDSFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'T' (1 nucleotides at position 65 to 65 in the user submitted sequence), (cause frameshift); cttctggattcaccttaggtgattaTttgtctaatgtgggtccgacagtttccagggaagcgacTtggagtgggtaggcttcattagaagtgcactttttggtgggaccacagaatacgccgcgtctgtgaaaggaagattcaccatctcaagagatgactccgagggcatcgcccacctagagatgaacagtctcaacaccgaggacacagccgtgtattattgtgctagagaccgcgattatcacgatagttggcccgattcttttgatgtctggggcccagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14603 JY8QFUQ01AWC8L productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +14604 JY8QFUQ01AEJJ5 No results +14605 JY8QFUQ01BFOJ9 productive Homsap IGHV3-30*01 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVREERAGAAYYFRYW in-frame + cctctggattctcctttagaacctacgctatgcactgggtccgccaggctccaggcaaggggctacactggctggccgttataacatatgatggaagtaataaatattacgcggactccgtggagggccgcttcaccatctccagagacaattccaagaagaccctttatctgcaaatggacagcctgagaggtgaggacacggcggtctattactgtgtgagagaggaaagagcgggagccgcttactactttcgctactggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14606 JY8QFUQ01B98S6 unproductive Homsap IGHV3-7*01 F 950 93.12 203/218 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARVRGYYGGQYFDSW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggctggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggcccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14607 JY8QFUQ01CKNTI productive Homsap IGHV3-30*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CAKDELPWDTIEYYFDYW in-frame + ctctggattcaccttcaatattttttctatgcactgggtccgccaggctccaggcaagggactagagtgggtgtcacttgtttcatatgatggatctaagaaaaagtacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatgagctgccttgggacacaattgaatattattttgactattggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14608 JY8QFUQ01AD591 No results +14609 JY8QFUQ01A1U7S productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F (see comment) 669 79.44 170/214 nt 78.97 169/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-10*01 F 2 8 8 21 8.8.21 [0.17.38.11] CARERRPGGYPNGYHHFYGMDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); ctctgatacaattagtcgttatggcatgcactgggtccgccaggctccaggcaaggggctggagtggctggcaattatttcatatgatggaaataGggatatatgttggagactccgtgaagggccgcttcaccgtttccagagacaacgccgggaggactctgtttctgcaaatgaacagtctgagaggtgatgacaccgccacatatttttgtgcgagagagcggcgtccgggtggctatccaaatggctaccaccatttttacggcatggacgtctggggccaagggaccagggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14610 JY8QFUQ01AH5YV productive (see comment) Homsap IGHV3-30*07 F 836 87.91 189/215 nt 86.98 187/215 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [1.16.37.11] CASLGSYESSGPRW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 74 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ctctggattcctcttcagtagttatgctatacactgggtccgccaggctccaggcaaggggcttgagtgggtgcggttgtttcatatgatggaaataataaatttacgcagactctgtgaagggtcgattcagcctctccagagacaactccaagagcacggttgatctgcaaatggacaacttgagatccgaagacacggctgtatattattgtgcgagcctcggttcctatgagagcagtggtccccgatggggcccgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14611 JY8QFUQ01BWET8 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 2 8 7 11 8.7.11 [2.17.37.11] CARDRQSWGIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 124 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcagtaacaactacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggtgacacatactacgcagactccgtgaaggccgattcaccatctccagagacaacgccaagaatacactttttcttcaaatgacttccctgagagtcgaagatacggccatttattactgtgctagagatcgtcagagctgggggattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14612 JY8QFUQ01C1V5R unknown (see comment) Homsap IGHV1-NL1*01 P 84 56.41 44/78 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccaga +14613 JY8QFUQ01DRERH unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt 92.79 206/222 nt 8 7 X 8.7.X [4.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaagggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14614 JY8QFUQ01B4QGR productive Homsap IGHV4-39*02 F 956 92.76 205/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.17.38.11] CARIVVRQFDQW in-frame - tctctggtgactccatttccagtactagttattactggggctgggtccgccagccccagggaaaggggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14615 JY8QFUQ01DCK7H productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 852 85.59 196/229 nt 85.15 195/229 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-21*01 F 2 8 10 8 8.10.8 [3.17.38.11] CTSNSWLDRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); tgcagcctctggattctcGtttcagtaatgcctggatgaactgggtccgccaggctccagggaaggggctggaatgggttggccatataaaaagggacatcgatggtggcatagcaaactacgcaacatccgtgaagggcagattctccatcgcaagagatgattcaaagaatatgatgtatttgcaaatgaacagcctgcaaatcgaagactcaggcgtttattactgcacctcaaattcgtggctcgaccgctggggccagggtaccaccgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14616 JY8QFUQ01BZNFS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 917 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 69 60.42 29/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CANWLSGTHSKFDYWG in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'CA' (2 nucleotides at position 16 to 17 in the user submitted sequence), (cause frameshift); tctggattcacccttCAggcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctganagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactgggggcaagggaagcccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag +14617 JY8QFUQ01CJBMZ unproductive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1002 96.73 207/214 nt 96.26 206/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARRQQLRDFDYW in-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagctactatttgcactgggtgtgacaggCcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcgaggagacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14618 JY8QFUQ01CEUYJ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 940 93.06 201/216 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [2.17.38.11] CARAPRTATLLDPW in-frame - gtctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14619 JY8QFUQ01AMG29 productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); tggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtGgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14620 JY8QFUQ01AYJXD productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14621 JY8QFUQ01DJU83 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARPLVDHEDSGYLPSG in-frame - cgtctggattcaccttcagtgactatgccatcctctgggtccgccagactccaggcaaggcgctggagtgggtggcagttatatggcatgatgggagtgaaaagttctatgccgactccgtgaagggccgtttcaccatctccagagacaattccaagaagaccctttatctggaaatgagcaatctgagagccgaggacacggctgtgtatttctgtgcaaggcctcttgtggaccatgaagatagtggttatctgccttctgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14622 JY8QFUQ01DKZQV productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 962 92.41 207/224 nt 91.96 206/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 7 7 8 7.7.8 [5.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) ccgtctgcagcctctggattcattgtcaatagcactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14623 JY8QFUQ01A8H2O productive (see comment) Homsap IGHV3-7*02 F 937 92.24 202/219 nt 91.78 201/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [2.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) agcctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctcccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14624 JY8QFUQ01BLMKY No results +14625 JY8QFUQ01CCERP No results +14626 JY8QFUQ01BF1FJ productive Homsap IGHV3-48*03 F 888 89.55 197/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARESWWSGFYGWYDPW in-frame - agcctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14627 JY8QFUQ01B84FR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 901 90.0 198/220 nt 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [2.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) cagcctccgaattcatccttnacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14628 JY8QFUQ01B9EP0 unproductive (see comment) Homsap IGHV3-33*05 F (see comment) 549 72.81 158/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] YC**RTWIQ*LRP#DYW out-of-frame + stop codons Low V-REGION identity (72,81% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgcctgcatgacttaccgttcggtcgacacgacggctgtcttattattgttagtaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14629 JY8QFUQ01DTWKQ unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1000 95.43 209/219 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [2.17.38.11] CVRGDYGGDPRTLLRP#YGLDVW out-of-frame - gcctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaacgggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgacccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14630 JY8QFUQ01AOR4M productive Homsap IGHV3-7*01 F 950 93.12 203/218 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGHW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14631 JY8QFUQ01B9YFD No results +14632 JY8QFUQ01C8K7Q unknown (see comment) Homsap IGHV3-9*01 F 1017 96.77 210/217 nt 95.85 208/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); ctctggattcagGatttgatgaGttatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagctggaatagtggtagtatagggtatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattactgtgcaaaaggggatagtggtggttatacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14633 JY8QFUQ01BYFTC productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame - ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14634 JY8QFUQ01AMV93 productive Homsap IGHV3-7*01 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CATISDYRFEFW in-frame + cctctggattcacctttagtggctattggatgagttgggtccgccaggctccggggaagggtctggagtgggtggccaacatagagaaagatggaagtgacataaagtatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtctctgcaaatgaacagcctgagagccgacgacacggctatttattactgtgcgaccattagtgactaccgatttgaattctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14635 JY8QFUQ01C3KZ3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'ATG' (3 nucleotides at position 87 to 89 in the user submitted sequence), (do not cause frameshift); ctctggattcgactttagcggctttgccatganctgggtccgccaggccccagggaaggggctggagtgggtctcaactattactaATGgtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14636 JY8QFUQ01B54IS unproductive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARERGNSYGEIDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggcccagggaaccctggtcaccgtctcctcagcttccaccaaggggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14637 JY8QFUQ01BL6V1 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 750 83.64 179/214 nt 83.18 178/214 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 7 18 8.7.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BL6V1 ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 93 of V-REGION: 'A' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift); ctctggattcagtttcactggttttaccgtgatctgggtccgccaggctccaaggaaggggctggaatggatctcatccgtcactactaatggtctcacgtactacgcagactcagtagagggccgattcaacatctccagggacaacgccaacaatttagtgtttctgcaaatgaacAaccctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14638 JY8QFUQ01CJ967 productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaagggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14639 JY8QFUQ01BI54H unproductive Homsap IGHV3-11*01 F 851 88.07 192/218 nt Homsap IGHJ2*01 F 157 77.36 41/53 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CADINWV#WCFDLW out-of-frame + cctctgaaatcaccttcagcgaccactacatgagctggatccgccaggctccaggaaaggggctggaatggatttcatatattagcaccagtggtaatatgatctattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaggtcgatgtatttgcagatgaacagtctgagagccgaggacacggccgtctatttctgtgccgatataaactgggtgactggtgcttcgatctctggggccgtggcaccctggtcaccggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14640 JY8QFUQ01BRF9W unproductive Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGEGDPFF##YYSGLDVW out-of-frame - ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14641 JY8QFUQ01ANR0Z productive Homsap IGHV1-18*01 F 885 90.65 194/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-10*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARVIRTNWLDPW in-frame + tggttacacctttactacctatggcgtcacctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggtaatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacagccgtatattattgtgcgcgagtgattcggaccaactggctcgacccctggggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +14642 JY8QFUQ01DTI0K productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt 91.4 202/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 27 of V-REGION: 'C' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); tctctggCtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14643 JY8QFUQ01CZ5H7 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 108 53.33 72/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14644 JY8QFUQ01BZ5GU unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 819 97.66 167/171 nt 8 7 X 8.7.X [1.17.23.X] null + No rearrangement found cctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttc +14645 JY8QFUQ01CCSL0 productive Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + cctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14646 JY8QFUQ01DUY4L productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1105 100.0 222/222 nt 99.55 221/222 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD6-6*01 F 2 8 10 16 8.10.16 [1.17.38.11] CTRRSIADNFYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); tctgggttcaccttcagtggctctgctatgcactgggtccgccaggcttccgggaaagggctggagtgggttggccgtattagaagcaaagctaacagttacgcgacagcatatgctgcgtcggtgAaaaggcaggttcaccatctccagagatgattcaaagaacacggcgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtactagacggagtatagcagataacttctactactacggtatggacgtctggggccaagggaccacagtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14647 JY8QFUQ01AU0JI productive Homsap IGHV3-66*02 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame + ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14648 JY8QFUQ01B1XIV productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14649 JY8QFUQ01CU3FW unknown (see comment) Homsap IGHV3-66*02 F 743 92.44 159/172 nt 91.86 158/172 nt 8 7 X 8.7.X [4.16.21.X] null + No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) tctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaagggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgta +14650 JY8QFUQ01BNJCF No results +14651 JY8QFUQ01AT0AG No results +14652 JY8QFUQ01A0D0L No results +14653 JY8QFUQ01A8VTH productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1045 95.61 218/228 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [2.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + tctccgggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +14654 JY8QFUQ01A7BV6 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1043 98.6 212/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-3*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARGYDFWSTYRGYNWFDPW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctcttacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgaactctgtgaccgctgcggacacggccgtgtattattgtgcgagaggttacgatttttggagtacatatcgtgggtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14655 JY8QFUQ01AO7UP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 838 87.21 191/219 nt 86.76 190/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); ctccgggagttcacctttagtagtttctGggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14656 JY8QFUQ01A3L37 productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-3*01 F 1 8 8 20 8.8.20 [0.17.38.11] CARDHRSGALEWSHHYHGMDVW in-frame + tggttacatcttcacccactatggtatcaactgggtgcgccaggcccctggacaagggcttgagtggatgggatggatcagcgcctacagtggtaacacaaagtatgcacagaaggtccagggcagagtcaccatgaccacagacacttccacgagtacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagatcacagaagcggggctttggagtggtctcaccactaccacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +14657 JY8QFUQ01A0XAA productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 840 88.32 189/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [1.17.38.11] CTRGRSDAWELSDHW in-frame + cgacgatgggtcctgcagaaactgcttctggagttggatccgccagtccccagggaaggggctggagtggattggggaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagtcgagtcaccatatcattagacacgtccaacaaccaagtctccctgaggttgagctctgtgaccgccgcggacacggctgtgtattactgtacgcgagggcgatccgacgcgtgggaattatcggaccactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +14658 JY8QFUQ01CLLOA productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14659 JY8QFUQ01AQJ09 No results +14660 JY8QFUQ01CHMWW productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 760 83.8 181/216 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [2.17.38.11] CARGTRYNNGLDAFDVW in-frame - Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14661 JY8QFUQ01CQQYZ productive Homsap IGHV3-9*02 F 891 90.32 196/217 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + ctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagnnccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14662 JY8QFUQ01A3RHW unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 425 76.35 113/148 nt 75.68 112/148 nt 8 8 X 8.8.X [1.17.14.X] null - No rearrangement found Low V-REGION identity (76,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggacaacataatgccagatggaggtgagAaaattctacgtggtcgtcgcatgcctggtccagggcttcttccccca +14663 JY8QFUQ01B0SHL unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt 89.95 197/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [2.17.38.11] CARDRLTISALDYW in-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); gcctctggattcacCctttaacaactaCggccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14664 JY8QFUQ01BGTOW unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14665 JY8QFUQ01CTO8B productive Homsap IGHV3-7*01 F 882 89.86 195/217 nt Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARVNKDSTDMW in-frame + ctctggattcacctttagtgactattggatgaggtggttccgccagcctccaggaagggggctggagtgggtggccagcataaaagaagatggaagtgagaaaggttatgtggactctgtgaagggccgcttcaccatcgccagagacaacgcccagaaatcactgtttttgcagatgaacagcctgagaggcgaggacacggctgtgtatttctgtgcgagagtcaacaaggactctactgatatgtggggccaagggacaatggtcaccgtgctcttcagcatccccgaccagccccaaggtcttcccgctgagctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttcccccag +14666 JY8QFUQ01A7HR7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + cctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggctt +14667 JY8QFUQ01BBCX9 productive Homsap IGHV3-30*15 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD5-18*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARNELPWDTREYYFDYW in-frame + tctccggattcacctttagtaaatattccatgaactgggtccgccaggctccaggcaaggggctcgagtgggtggcacttatatcatacgatggaagtagaaaaatctacgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactactttgactattggggccagggaaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14668 JY8QFUQ01CJRRG productive (see comment) Homsap IGHV4-61*02 F 830 86.43 191/221 nt 85.97 190/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARDTGQTYGRGPLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtgcctccataaataggggtaattattactGggaactggatccggcagcccgccgggaagggcctggaatggattggccgaatctatacaagtgggagcaccatctacaacccctccctcgggggtcgagtcaccatgactgtagacccgtccgagaatcagttcttcctgagactgagttctgtgaccgccgcagacacggccgtttatttttgtgcgagagacactggacaaacctacggtcggggccctttggactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14669 JY8QFUQ01BZWQB No results +14670 JY8QFUQ01DIS4R productive Homsap IGHV3-11*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame + ctctggattcagctttagcaactttgccatgacttgggtccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +14671 JY8QFUQ01AKDFZ productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14672 JY8QFUQ01BGAKM No results +14673 JY8QFUQ01CCUFF productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14674 JY8QFUQ01DI4E3 No results +14675 JY8QFUQ01AOMW2 productive Homsap IGHV3-7*03 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame + cctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14676 JY8QFUQ01AJJIF unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +14677 JY8QFUQ01DLUV5 productive (see comment) Homsap IGHV3-48*04 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 96 of V-REGION: 'G' (1 nucleotides at position 190 to 190 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagaGggcgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14678 JY8QFUQ01AP8WK unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); ctcaggattcacgtttagcaggtatgccatgaactCgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgataCctggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14679 JY8QFUQ01CWT79 No results +14680 JY8QFUQ01A98LD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14681 JY8QFUQ01CZJ6H productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame - gttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14682 JY8QFUQ01CE9X2 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1014 95.91 211/220 nt 95.0 209/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'TC' (2 nucleotides at position 53 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'A' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtagtagttactactggggctggatccgccagTCccccagggaaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtAccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14683 JY8QFUQ01A0005 productive Homsap IGHV4-39*03 F 929 91.36 201/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14684 JY8QFUQ01CJLXD productive Homsap IGHV1-58*02 F 925 92.96 198/213 nt Homsap IGHJ6*02 F 188 84.62 44/52 nt 8 8 9 8.8.9 [X.17.38.11] CVADRNGFDVW in-frame - ggattcaccttcgctagttcgtctatacagtgggtgcgacagactcgtggacaacgccttgagtggataggatggatcgtcgttggcagtggcaacacaaagtacgcacagaagttccagggaagagtcacctttaccaaggacatgtccacaagcacagccttcatggagctgaacaacctgagatccgaggacacggccgtgtattactgtgtggcagatcgaaacggtttcgacgtctggggccaagggaccacggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14685 JY8QFUQ01AUYLV No results +14686 JY8QFUQ01BSGO4 productive Homsap IGHV3-7*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + ctctagattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcc +14687 JY8QFUQ01BN5MB productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14688 JY8QFUQ01BS58Q productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 861 88.18 194/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARQLSGDYASFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggtgcctccatcaccagtggtactttttactgggcctggatccgccagcccccagggaaggggctggagtgggttggcaatatctattctagtggtgtcgcctattacaacccgtccctcaagagtcgagtcaccatgtccgtcgacacgtccaagaatgagttttccctgacactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14689 JY8QFUQ01CNW0Z unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F 619 87.97 139/158 nt 8 8 X 8.8.X [1.17.18.X] null - No rearrangement found ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcatacattagtgggagtgcgactaccatatcctacgcagactttgcgaagggccgattcaccatctccagggcttcttccccca +14690 JY8QFUQ01AL269 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*01 F (see comment) 90 60.32 38/63 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctgggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14691 JY8QFUQ01BC9RZ productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1020 97.66 209/214 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD6-13*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARASSAWYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tggatacaccttcaccagttactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcaaccctagtggtggtagcacaagctacgcacagaagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtgtacatggaggtgagcagcctgagatctgaggacacggccgtgtatcactgtgctagagctagcagcgcctggtacggtctagacgtctggggcctagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14692 JY8QFUQ01CMXI4 productive Homsap IGHV1-2*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [0.17.38.11] CARGGTVTAGGPRIVFGYW in-frame - tggctacaccttcaccgactactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcaaccctgacggtggtagcacaaagtatgcacagaaatttcagggcagggtcgccgtgaccagggacacgtcaattagcacagcctacattgaggtgaccagactgacatctgacgacacggccgtgtattattgtgccagaggagggactgtgacagcaggtggtcctcgtattgtctttgggtactggggccagggaacgttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14693 JY8QFUQ01DATSJ productive Homsap IGHV3-11*01 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFDYW in-frame + cctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcatacattagtgggagtgcgactaccatatcctacgcagactttgcgaagggccgattcaccatctccagggacaacgccaagaactcggtgtatctgcaaatgaacagcctgagagccgaggacacggccacgtattattgtgtgaggcgggtctggggatacagttatggttccgtttcgtattacttcgactactggggccagggaatcccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14694 JY8QFUQ01AEM97 productive Homsap IGHV3-74*03 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [2.17.38.11] CARHKPLGATSLDYW in-frame - gcctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggctgtatattattgtgcgagacataagccactgggagctacaagccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca +14695 JY8QFUQ01C3UHK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctncctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +14696 JY8QFUQ01A5VJ3 productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-3*01 F 1 8 8 20 8.8.20 [0.17.38.11] CARDHRSGALEWSHHYHGMDVW in-frame - tggttacatcttcacccactatggtatcaactgggtgcgccaggcccctggacaagggcttgagtggatgggatggatcagcgcctacagtggtaacacaaagtatgcacagaaggtccagggcagagtcaccatgaccacagacacttccacgagtacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagatcacagaagcggggctttggagtggtctcaccactaccacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14697 JY8QFUQ01AU8Z8 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDFIMV#DYW out-of-frame - ctctggattcaacttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagtcattgcatacaatggaggaaatatatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaaggataccctgtacttgcacatgaccagtctgagacctgatgacacggccatgtattactgtgcgaaagactttattatggttgcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14698 JY8QFUQ01B20JA No results +14699 JY8QFUQ01CF5U2 productive Homsap IGHV3-7*01 F 887 89.91 196/218 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGMDVW in-frame + cctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgccctggtcccagggcttcttccccc +14700 JY8QFUQ01DL6EM unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 1 8 8 X 8.8.X [1.17.38.11] CAREGGGAVRRK#YFDYW out-of-frame - cctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgcgagaggggggcggggcagttcgtcggaagactactttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14701 JY8QFUQ01AE7R4 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRGGVSGAFRWG#FDYW out-of-frame + stop codons ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgacgacacggctgtttactactgtgtgagagggggagtcagtggggccttcaggtggggggtttgactactggggccagggaaccctggccaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14702 JY8QFUQ01CDCCZ No results +14703 JY8QFUQ01DKEJK productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca +14704 JY8QFUQ01C85KU productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcg +14705 JY8QFUQ01BKM97 No results +14706 JY8QFUQ01BMC0P productive (see comment) Homsap IGHV3-7*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [2.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) gcctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14707 JY8QFUQ01BIDEZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 7 11 8.7.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 88 in the user submitted sequence), (cause frameshift) cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtgtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14708 JY8QFUQ01BRTW7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt 8 8 16 8.8.16 [1.17.38.11] CVKDVISFGALIVFNLNI (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctggattcagatttagcagctatgccatgagctgggtccgccagactccagaaaaggggcttgaatgggtctcaggcatcaatgataacggtcgaagcataaactacgcgggctccgtgaagggccggttcaccatctccagagacaattccaagagcacgttgtatctgcagatggatagcctgagccccgaggactcgggcatatattattgtgtgaaagatgtgatttcctttggggcacttatcgtcttcaacttgaacattgggcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14709 JY8QFUQ01DWT03 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.4 194/217 nt 88.48 192/217 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [2.16.38.11] CAKDQSCIVGPCGFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) gcctccgaattcatccttgacagttatgccatgagttgggnccgcaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14710 JY8QFUQ01CKXCL No results +14711 JY8QFUQ01DFGYO unproductive Homsap IGHV3-48*04 F 958 93.98 203/216 nt 92.59 200/216 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGRIVSVGMSGWF##PW out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 82 of V-REGION: 'A' (1 nucleotides at position 150 to 150 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 177 to 177 in the user submitted sequence), (cause frameshift); tctggactcaccttcagcagctatagtatgaactgggtccgccaggctccagggaaAGggggctggagtgggtttcatatattagtagtactagtagtaccataaactacgcagactctgtgaagggccgattcaccatctccagagacAaacgccaagaacaccctgtatctgcaAaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgaacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +14712 JY8QFUQ01BRYU1 No results +14713 JY8QFUQ01BE108 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 809 86.51 186/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CGTSSRAWGADAFDIW in-frame + cctctgggctcagcgtcagtaactaccgcatgggctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagagatgatagtacagatcatgtagattccgtgaagggccgattcaccgtttcccgagacaattccaagaacacattgtaccttcagatgaacagtgtgacagccgaggacacggccgtttattattgtggaactagttcccgcgcctggggcgctgatgcctttgatatctggggccaggggacactggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14714 JY8QFUQ01C3KUP No results +14715 JY8QFUQ01DKQXX unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactanttccccgaaccggtgacggtgtcgtgaactc +14716 JY8QFUQ01CICNZ unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14717 JY8QFUQ01ADUL0 unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F (see comment) 773 84.65 182/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 3 8 8 15 8.8.15 [0.17.38.11] CARRSNPNAMMAAFDIW in-frame - stop codons Low V-REGION identity (84,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ggattcagtcctagccgactttttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaacggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14718 JY8QFUQ01A0XM8 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtacttactactggacatGggatccgccaggacccagagaaagggactgagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14719 JY8QFUQ01DSKY7 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 985 95.37 206/216 nt 94.44 204/216 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); tctggattcacgttcagtagctactggatgcactgggtccgccGaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14720 JY8QFUQ01B15SH unproductive Homsap IGHV4-61*01 F 947 92.31 204/221 nt 91.86 203/221 nt Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD5-18*01 F 3 10 7 X 10.7.X [1.17.38.11] CTRGGSTLMT#PW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcggtagtactaactactggagctggattcggcagcCccccagggaagggactggaattcattgggtatatctattccagtgggaggaccaactacaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccagttctccctgaggctggcgtctgtgaccgctgcggacacggccgtgtattactgtacgagggggggcagtacacttatgacagcccgtggggacaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14721 JY8QFUQ01C4T4X productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14722 JY8QFUQ01BICD9 unproductive Homsap IGHV3-7*01 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKGGGNGDLDY## out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); acctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14723 JY8QFUQ01CAJVK productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*07 F 892 89.95 197/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [X.17.38.11] CTHLREEMSYEW in-frame - tggagtcaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14724 JY8QFUQ01CKGRK productive (see comment) Homsap IGHV3-11*01 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14725 JY8QFUQ01CIOUS productive Homsap IGHV1-2*02 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame + tggatatactttcaccgaccattatgtttactggatgcgacaggcccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14726 JY8QFUQ01CR92I unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14727 JY8QFUQ01CZX1A No results +14728 JY8QFUQ01B5YXL productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [2.17.38.11] CAKDLFQVSTTYFDYW in-frame - gcctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14729 JY8QFUQ01DIN2T productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14730 JY8QFUQ01BCX6Z unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRVVLMVHAMS#DFW out-of-frame - cctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcgggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14731 JY8QFUQ01CPKXR No results +14732 JY8QFUQ01A7NCV unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F (see comment) 266 57.8 126/218 nt 57.34 125/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (57,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); ggtctggatacatctttaatatccactggatcgcctGgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14733 JY8QFUQ01DDV4B productive Homsap IGHV3-7*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 8 13 8.8.13 [1.17.38.11] CATYGRFSFSPLDYW in-frame + cctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggagacggctgtctattattgtgcgacttacggaagattctcgttttctccccttgactactggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +14734 JY8QFUQ01ABZVD productive (see comment) Homsap IGHV3-7*01 F 904 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.37.11] CARGSYWHYDTFGDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 190 in the user submitted sequence), (cause frameshift) ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagcccgaggacacggctgtatatttctgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14735 JY8QFUQ01BIZYH unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 916 90.54 201/222 nt 90.09 200/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 9 X 8.9.X [1.17.38.11] CTTDRRGFVYTTS#FDFW out-of-frame + stop codons in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtgacgcctggatgagctgggtccgccagattccagggaaggggctggagtgggttggccgtataaaaacaaagctatgggtgagacaacagacttcgctgcacccgtgagaggcagattcagtatctcaagagatgattcaaaaaatacactgtatctgcacatgagtggcctgaaaaccgaggacacagccgtctattattgtaccacagatcggcggggttttgtctataccacctcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14736 JY8QFUQ01A7XAB productive Homsap IGHV4-4*07 F 890 90.7 195/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD4-17*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARDLPTVTTGALDIW in-frame + tctctggtggctccttcagtaattaccactggagctggatccggaagcccgccgggaaggaactggagtggattgggcgtatccatcacagtgggctcaccaactccaacccctccctcaagaatcgagtcgtcgtgtcagtggatacgtccaagaatcagttgtccctggagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagatcttcctacggtgactactggggctcttgatatctggggccaagggacaatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14737 JY8QFUQ01AGGN2 No results +14738 JY8QFUQ01AKHCX productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [1.17.38.11] CTRELRVAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcagtaccaaGgttcatgagctgggtccgccaggctccagggaaggGggctggagtgggtctcagtaatttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14739 JY8QFUQ01BDGDZ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1046 97.29 215/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14740 JY8QFUQ01BCKQ8 No results +14741 JY8QFUQ01CYIFV No results +14742 JY8QFUQ01CXQDP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14743 JY8QFUQ01CTYTD productive Homsap IGHV1-18*01 F 885 90.65 194/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-10*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARVIRTNWLDPW in-frame + tggttacacctttactacctatggcgtcacctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggtaatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacagccgtatattattgtgcgcgagtgattcggaccaactggctcgacccctggggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +14744 JY8QFUQ01B1HDC productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 794 84.62 187/221 nt 83.71 185/221 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFESW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tttccggtgactccatcaccagtactaattattactgGgggctgggtccgccagTcccccagggaagggtctggagtggattggaagtgtctattatcgggggacccagtacctcaacccgtctctccacaatcgagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtcttttggagtgataattgttaactactttgagtcctggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +14745 JY8QFUQ01ATVGB unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found ctctggattcatcttcagtagctactggatgcactggg +14746 JY8QFUQ01AXWIG productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14747 JY8QFUQ01C0QH5 productive Homsap IGHV3-66*02 F (see comment) 759 84.11 180/214 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-21*01 F 3 8 7 11 8.7.11 [1.17.38.11] CARHLMVYALDVW in-frame + Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaggggctggagtgggtctcagtcttatttagtactggcactgcatactacgcagactccgtgaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14748 JY8QFUQ01BVMIC productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 938 91.86 203/221 nt 90.95 201/221 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 12 8.8.12 [2.17.38.11] CARRDVGSHAFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); ggggttctggatTacaattttaactacgactggatcgGgctgggtgcgccagatgcccgggaaaggcctggagtggatggggatggtctatgttggtgactctgatgctagatacagcccgtcctccgaaggccaggtcaccatctcagccgacaaggccatcagtaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggatgtgggttcacatgctttcgatctgtggggccaagggacaatggtcaccgtttcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14749 JY8QFUQ01CJK0W productive Homsap IGHV3-30*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame + cctctggattcaacttcaggacctattctatgcactggctccgccaggctccaggcaagggactagagtgggtatcagttatttcatatgatggaactaagaagaattatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctacaaatggacagcctgagacctgaggacacggctgtgtattactgtgcgagagatgaactgccttgggatacaatagagtattactttgactactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +14750 JY8QFUQ01B7XFX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - agcctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14751 JY8QFUQ01B212Y unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 901 90.41 198/219 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-1*01 F 1 8 8 X 8.8.X [2.17.38.11] CARAKSSDPSQLVR#PG out-of-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattactgtgcgagagcaaaaagtagtgatccgtcccaactggttcgacccctggggccacgggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14752 JY8QFUQ01BFOHN productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 752 82.65 181/219 nt 80.82 177/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*01 F 2 8 8 16 8.8.16 [2.17.38.11] CAMRFCGGPECYPYLDNW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 61 to 62 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 90 of V-REGION: 'G' (1 nucleotides at position 180 to 180 in the user submitted sequence), (cause frameshift); gcctctgggttcacattcagtGaactactggatccactgggtccgccaagctccaggaaaAGggggctanagtgggtcgcacgtattaatgatgctggaaagcgtgccgacttcgcGacatttcgtgaagggccgattctccatctcccgagacaacgccaagaacacagtgtatctggGaaatgactagtctgagagtcgacgacacggctgtctatttttgtgcaatgcgattttgtggtggtcctgagtgctacccttatcttgacaactggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14753 JY8QFUQ01AJUBJ unproductive Homsap IGHV4-61*02 F 834 86.82 191/220 nt 85.91 189/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 1 10 7 X 10.7.X [1.17.37.11] CARCPNYNIGTPG#FDYW out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'A' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 217 in the user submitted sequence), (cause frameshift) tttctggtgtctccatgagcaatgAgtccctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatattctgtgcgaggtgtcccaattacaacattgggaccccggggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14754 JY8QFUQ01CZG7X productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggatcacctttggttattgatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14755 JY8QFUQ01DKTDW No results +14756 JY8QFUQ01BKDOO productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 917 92.09 198/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 7 10 8.7.10 [1.17.38.11] CARGGLEPVDYW in-frame + tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14757 JY8QFUQ01AFMA5 No results +14758 JY8QFUQ01ANQVZ productive Homsap IGHV3-13*01 F 981 94.93 206/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame - agcctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14759 JY8QFUQ01ANTUE No results +14760 JY8QFUQ01BNITY productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 919 91.32 200/219 nt 90.41 198/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) ggcctctggattcaccCtttggttattatggcatgactgggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14761 JY8QFUQ01ADBSF productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*03 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 864 88.94 193/217 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [1.17.38.11] CACGHMRDGYDVW in-frame - ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +14762 JY8QFUQ01CC2VZ productive Homsap IGHV3-66*02 F (see comment) 759 84.11 180/214 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-21*01 F 3 8 7 11 8.7.11 [1.17.38.11] CARHLMVYALDVW in-frame - Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaggggctggagtgggtctcagtcttatttagtactggcactgcatactacgcagactccgtgaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14763 JY8QFUQ01BYPS6 productive (see comment) Homsap IGHV4-61*07 F 905 90.83 198/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 9 7 13 9.7.13 [2.17.38.11] CAREDGSGRRHFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'AG' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 34 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) gtctctgggtgactccatcaacagggtggttatttctgGgagctggatccgccagcAGcccacgggaagggcctggtgtggattggGgtacatctattacaGgggggagcacctactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14764 JY8QFUQ01CGHQQ productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 697 80.56 174/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [2.17.38.11] CARLDGHFDLW in-frame - Low V-REGION identity (80,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14765 JY8QFUQ01BMECE productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDPFIAATGRPWYFEYW in-frame + ctctggattcaccttcagcagctatggcatgcactggttccgccaggctccaggcaaggggctggagtgggtggcagctatctcatatgatggaattgacaaatattatgcagactccgtgaagggccgattcaccatctccagagacaatgccaaaaacacgctgtatctgcaattgaacagcctgagaagtgaagacactgctgattactactgtgcgaaagacccatttatagccgcaactggccgcccctggtactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct +14766 JY8QFUQ01CQMR7 unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPPSGNLR*LR##W out-of-frame + stop codons cctctggattcaccttcgataactatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcaaaggatggaagtattgaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacaatttatctgcaaatgaacattgtgagggttgaggacacggctatgtattactgtgcgagacccccttcgggcaacttacggtgactacgtgaactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14767 JY8QFUQ01C5GP7 productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [0.17.38.11] CATSDVGARKFDYW in-frame + tggttacacctttaccagatatggtattagttgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcagcgtttccaatggtgacacaaactatgcacagaagctccagggcagagtcaccatgaccgcagacccatccacgagcacagcctacttggaactgaggagcctgacatctgacgacacggccgtatattactgtgcgacatctgacgttggagctcgaaagtttgactactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctccgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14768 JY8QFUQ01A3IBC No results +14769 JY8QFUQ01BM2F6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 1 8 8 12 8.8.12 [1.17.38.11] CGKQLGAHKGADYW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattcacctttagtagttctggcatgtattgggcccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatgccacaaattacgcagactccgtgaagggccggttcaccatctccagagacaactccatgaacacactgtatctgcaaatgaacagcctgggaaccgatgacacggccttatattactgtggaaagcaattgggggcccataaaggggctgactactggggccaggggaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14770 JY8QFUQ01BYW33 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14771 JY8QFUQ01AWIJ1 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 782 85.12 183/215 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CATVRHLGERIFDFW in-frame + tctctggggccaccatgagtagtttctactggagctgggttcggcagtccccagggaggggactggagtggattggatttgtttcttacagtgggcccaccaactacagcccctccctcaagagtcgagtcaacttatcactggacgcggccaacaaacagttctctttgcagctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14772 JY8QFUQ01AK3ZY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame - tctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14773 JY8QFUQ01BBT9T No results +14774 JY8QFUQ01AQH68 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1031 97.25 212/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame + gctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtggtggtgatagcacatactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +14775 JY8QFUQ01CG6PQ productive (see comment) Homsap IGHV3-7*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [2.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) gcctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14776 JY8QFUQ01A26A4 unknown (see comment) Homsap IGHV3-48*02 F 954 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcagcttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccataaactatgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtcagggcttcttcccc +14777 JY8QFUQ01BQEVD No results +14778 JY8QFUQ01AHFYO unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARLGQLALDY## out-of-frame + in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); gttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgGggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactgggggcgagggaaccctgatttccgtctcctcagcctccaccgaacgggcccatcggtcttccccctggcaccctcctgccaagagcacctctgggggcacagcggccctgggctgcctcggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14779 JY8QFUQ01B5BYX unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt 93.55 203/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); ctccggattcaccGtttagtagttactggatgcactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactgggggccagggaagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +14780 JY8QFUQ01CANBH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctaggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14781 JY8QFUQ01BRUUK unproductive Homsap IGHV3-72*01 F 926 90.62 203/224 nt 89.29 200/224 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD2-8*02 F 3 8 10 X 8.10.X [2.16.38.11] CTRDTTDTGGQSFNGLDV## out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) gcctctggtttccCccttcagtgaccacttcatggactgggtccgccagctccagggaagggcctggagtAgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctgggggccaggggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14782 JY8QFUQ01C7OY5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +14783 JY8QFUQ01CBC07 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 662 77.98 170/218 nt 77.06 168/218 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD3-3*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIIREGLDRW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (77,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); tgtctggtggttctactcgcactaaccattggtCggaattgggtccgccagAccccccgacaagggactggagtggattggagaagtctataagagtggacagaccaactacaacccgtcactccagagtcgcgttgacctcttcattgacaactccaggaatcagatctccctaaatatgagagatgtgaccgccgcggacacggccgtctattactgcgcgagagaagacattattcgggagggccttgaccgctggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14784 JY8QFUQ01C86EV productive Homsap IGHV3-9*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccgtgacggtgtcgtggaaactca +14785 JY8QFUQ01AD2KE productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14786 JY8QFUQ01B5QQQ No results +14787 JY8QFUQ01CNFQ4 unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [1.17.38.11] CARHEGYNSRYYYFGY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); gttctggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaAaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggcccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggctcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgctgcctggtccagggcttcttcccccaa +14788 JY8QFUQ01AR87F unproductive Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CATSPFTVTTGKDAY## out-of-frame + cctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggcccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14789 JY8QFUQ01COGA1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame - ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14790 JY8QFUQ01CO8CK productive (see comment) Homsap IGHV4-4*07 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaAaaactctaactacaaccCcctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagccctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14791 JY8QFUQ01C531H productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaAaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14792 JY8QFUQ01ACLFY productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-23*01 ORF 2 8 8 10 8.8.10 [1.17.38.11] CVKDLLGGDPFW in-frame + ctctggattcaccttcagtcgctatggcttgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcagatgatgggaagaataaattctatacagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgatgtttgtgcaaatgaacagtctgagagctgaggacacggctgtgtattactgtgtgaaagacctactaggtggtgaccccttttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14793 JY8QFUQ01BBYXJ unproductive Homsap IGHV3-7*03 F 892 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [2.17.38.11] CAKDASRYYYNSYCDN## out-of-frame + in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggGccaacataaaggaagacggaagtgagagatattatgtggactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc +14794 JY8QFUQ01ALGAH unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CARERSAAGVVFFDF# out-of-frame - cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagagagatcagcagctggagtcgtcttctttgacttttgggccagggagccccggtcaccgtctccagagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14795 JY8QFUQ01AO8B3 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 927 92.17 200/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) gcctctggattcacCctttggttattatggcatgactgggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14796 JY8QFUQ01AM7WT productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattaggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14797 JY8QFUQ01DXF6K productive Homsap IGHV3-48*01 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDASWSYYAYFDSW in-frame - tctggattcaccctcagtagcaacagcatgaactgggtccgccagactccggggcaggggctggagtgggttgcacacattagtagtagcagcgataccatatactacgcagactctgtggggggccgattcaccatctccagagacaatgccaagaactcactgcatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcgagagatgccagttggagctactacgcttactttgactcttggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14798 JY8QFUQ01CI6IF unproductive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 824 86.7 189/218 nt 86.24 188/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-21*01 F 2 9 7 X 9.7.X [1.17.38.11] CTSREHALVVNSR#DYW out-of-frame - stop codons in CDR1-IMGT at codon 36 of V-REGION: 'GTC' (3 nucleotides at position 24 to 26 in the user submitted sequence), (do not cause frameshift); tgtctggtgtctccgtcaccagcGTCagtcactggtggacctgggtccgccagcccccagggaagggactggagtggattggagaaatctattattatggcatcaccaatttcaacccgtccctcaagagtcgaatcagcatgtcagtggacgagtccaagaaccagttctccctgagactgacttctgttaccgccgcggacacggccgtttattattgtacgagtcgcgaacatgctttagtggtcaattcacgggtgactactggggccagggaaccctgatgaccgtcacctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14799 JY8QFUQ01CEE4G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 92.0 184/200 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 3 8 11 3.8.11 [X.17.38.11] CARFGPLTRPDYW in-frame - ccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14800 JY8QFUQ01BT291 unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [2.17.38.11] CARRLNNYDSGEYAMDV## out-of-frame + in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); ggttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgGggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctgggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14801 JY8QFUQ01AL4SS unproductive (see comment) Homsap IGHV4-61*01 F 934 91.44 203/222 nt 90.54 201/222 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD3-16*01 F 3 10 7 X 10.7.X [2.17.38.11] CTKGGIHL*QPV# out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'GC' (2 nucleotides at position 55 to 56 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagcggtagtactaactactggagctggattcggcagGCccccaggggaagggactggaattcattgGggtatatctattccagtgggaggaccaactacaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccagttctccctgaggctggcgtctgtgaccgctgcggacacggccgtgtattactgtacgaagggggggatacacttatgacagcccgtgggggacaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14802 JY8QFUQ01CCETR No results +14803 JY8QFUQ01AWZVZ No results +14804 JY8QFUQ01CMUK3 unproductive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 849 88.79 190/214 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [0.17.38.11] CARGGGFQ*TSGEG#YYNGLDVW out-of-frame + stop codons tggatacaccttcagcagttattatatacactgggtgcgacaggcccccggacaggggcttgagtggatggcaatgatcaacccaagtggtggtagtaccacgtacgcacagaagttccagggcagactcatcgtgaccagggacacgtccacgagtagtgtctacatggacctgagtagcctgagatctgaggacacgggcgtctatttctgtgcgagaggggggggcttccagtaaacgtcaggtgaagggactactacaacggtctggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc +14805 JY8QFUQ01A2QA6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14806 JY8QFUQ01C8EBK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - gcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14807 JY8QFUQ01DGDK1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame - ctctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14808 JY8QFUQ01BHLLE productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 909 91.24 198/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDAFEMW in-frame - ctctggattcacctttagtaaccattggatgaattgggtccgccaagctccagggaaggggctggagtgggtcgctggtatcagttggaatggtggcaaagcaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcaatgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14809 JY8QFUQ01CW7XW productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); tctggattcatcttcagtagctatgccatgaattGgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14810 JY8QFUQ01C4YTG unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 124 72.0 36/50 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDTLEVVSNM#DAFDLW out-of-frame + stop codons cgtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatgatgatgcttttgatttgtggggccaagggacagtggtaatgtctcctcagcatccccgaccagcccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +14811 JY8QFUQ01AUEHV No results +14812 JY8QFUQ01CF445 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 8 8 9 8.8.9 [1.17.38.11] CAKEEVPNDYW in-frame - ctctggattcacctttagcaatgctgccatgacgtgggtccgccaggctccagggaaggggctagagtgggtctcaggtattagtattagtggtgatagaacatattacgcagactccgtgaagggccggttcaccatctctagagacaattccaagaataccgtgtatctgcaaatgaacagcctgagagccgaggacacggccatatattattgtgcgaaagaggaggtcccgaatgattattggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14813 JY8QFUQ01B4DOI productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 7 12 8.7.12 [2.17.38.11] CARAPGWMNPFDFW in-frame - tgtctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14814 JY8QFUQ01AYG9W unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [1.17.38.11] CANASPLYNWN#YFYYYGMDVW out-of-frame + tctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcaaccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctcccccctgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca +14815 JY8QFUQ01CFFY3 productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +14816 JY8QFUQ01AEFZP unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAEKKHYNSRTYLYNFDY## out-of-frame - ctctgggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcggaaaaaaaacattataattcgaggacttatttatacaactttgactactgggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14817 JY8QFUQ01DBMZV No results +14818 JY8QFUQ01CJBSY productive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 947 92.31 204/221 nt 91.86 203/221 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD6-19*01 F 1 10 7 10 10.7.10 [1.17.38.11] CAAYDSGWYKHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 99 of V-REGION: 'T' (1 nucleotides at position 206 to 206 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcaacagtggtgattactactggacctggatccgccagcaccctgggaagggcctggagtggattggatacatctattacagtgggagcacttactacaatccgtccctggagagtcgagttaccatatcaatagacatgtctaagaaccagttctccctgaaagtgagctctgtgactgccgcggatacTggccgtgtatcattgtgcggcgtatgacagtggctggtacaaacactggggccagggaaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttcccc +14819 JY8QFUQ01CE327 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*13 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-20*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDDKWAFDYW in-frame - cctctggattcaccttcagtcactatggtatacactgggtccgccaggctccaggcaaggggctagattgggtggcatttatatcatatgatggaagtaatgagttttacgcagactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgataagtgggcatttgactactggggccagggaaccctggtcgtcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14820 JY8QFUQ01DJBEG productive (see comment) Homsap IGHV3-74*03 F 855 88.48 192/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) cctctggattcactttccacacctcctggatgcactgggtccgccaagtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaAagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +14821 JY8QFUQ01B3XMD productive (see comment) Homsap IGHV3-7*01 F 837 87.56 190/217 nt 87.1 189/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CGRDERGADLPNDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggGactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagccccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctggggcctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14822 JY8QFUQ01C1GNB productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1008 96.31 209/217 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDVW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14823 JY8QFUQ01AK7F3 productive Homsap IGHV3-11*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame + ctctggcttcaccttcagtgactactacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtggaagtggaactaccatatcctacggagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtatctccagatgaacagcctgagagccgaggacacggccgtatattactgtgtgaggcgggtgtggggatacagctatggttccgtctcgtactattttgagtactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +14824 JY8QFUQ01CDGUR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14825 JY8QFUQ01DSGAI unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDYGDCRGGRCYAEPLDY## out-of-frame + cctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +14826 JY8QFUQ01CB5QB No results +14827 JY8QFUQ01CSFFN productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 800 86.05 185/215 nt 84.19 181/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'CAT' (3 nucleotides at position 54 to 56 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaggagttattattggagtTtggatccggcagcccccCATgggaaagggacCtggagtggCattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14828 JY8QFUQ01A3WMR No results +14829 JY8QFUQ01A3MRK unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFD#PW out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14830 JY8QFUQ01AEEU6 productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [1.17.38.11] CSNGYGDFPRRW in-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcagtttcagtgactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgacaaattctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14831 JY8QFUQ01BNARW unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-16*01 ORF or Homsap IGHV3-16*02 ORF or Homsap IGHV3-19*01 P or Homsap IGHV3-20*01 F 70 100.0 14/14 nt 3 X X 3.X.X [1.X.X.X] null - No rearrangement found ctctggattcacct +14832 JY8QFUQ01C717G productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 666 78.34 170/217 nt 77.88 169/217 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIVREGLDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (78,34% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'AC' (2 nucleotides at position 50 to 51 in the user submitted sequence), (cause frameshift); gtctggtggctccatcgccacttatcattggtggaattgggtccgccagACcccccggggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccggaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +14833 JY8QFUQ01AFU95 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 781 83.78 186/222 nt 82.88 184/222 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 9 13 8.9.13 [1.17.38.11] CATDSPTGYYAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) ctctgggttcGattttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14834 JY8QFUQ01BH6T6 No results +14835 JY8QFUQ01ALZYF productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 135 to 135 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccCttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14836 JY8QFUQ01BV1X0 unproductive Homsap IGHV3-48*02 F 976 94.91 205/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARPAGEGDPFS#YYSGLDVW out-of-frame - tctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgaccctttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14837 JY8QFUQ01DD1NB unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 904 91.2 197/216 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14838 JY8QFUQ01AA69Z productive Homsap IGHV3-11*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame - Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14839 JY8QFUQ01B6K22 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcactccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14840 JY8QFUQ01DONE0 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 855 88.48 192/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame + ttctggattcagtcctaccgatttttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14841 JY8QFUQ01AUIH8 productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame - cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14842 JY8QFUQ01CDF4N No results +14843 JY8QFUQ01CUYC1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.37.11] CAKEEGATGVYYVDHW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgagggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14844 JY8QFUQ01DRGHF unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 941 92.66 202/218 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD1-1*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDTGQWKDFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggcccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccgag +14845 JY8QFUQ01BJ9JS No results +14846 JY8QFUQ01CTT8H productive (see comment) Homsap IGHV3-48*04 F 1009 95.89 210/219 nt 95.43 209/219 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 7 8 16 7.8.16 [2.17.38.11] CARDAGGSGWYLYYFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) agcctctggattcaccttcagtagtataccatgcactgggtccgccaggctccagggaaggggctggaatgggtctcatccattagtagtagtagtactaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacggcctgagagccgaggacacggctgtttattcctgtgcgagagatgcggggggcagtggctggtacctttactactttgactcctggggccagggaaccctggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14847 JY8QFUQ01B3WRU No results +14848 JY8QFUQ01A8SI6 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 907 90.09 200/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARHSRLVRYFEFW in-frame - gtctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14849 JY8QFUQ01B81Q2 productive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14850 JY8QFUQ01CTCYU productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1060 100.0 213/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - tctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14851 JY8QFUQ01AXCOP productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14852 JY8QFUQ01BICWG productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14853 JY8QFUQ01B8TTF No results +14854 JY8QFUQ01CCU4L unproductive Homsap IGHV2-5*02 F 1044 92.21 225/244 nt 91.39 223/244 nt Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD2-21*01 F 1 10 7 X 10.7.X [9.17.38.11] CTHRRRYCEGADCFGGAFD#W out-of-frame + Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 31 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttctccgggttctctctcagGcacttctgGgagtgggtgtgggctggatccgtcagcccccaggaaaggccctagagtggcttgcagtcatttattgggatgacgagaggcgctacagtccatctctgaggagcggcctgaccatcaccaaggacacttccaaaaacgaagtggtccttacaatgaccaacgtggaccctatggacacagccacatattactgtacacacaggaggcgttactgtgagggcgctgactgctttggtggtgcttttgattctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14855 JY8QFUQ01BFBI1 productive (see comment) Homsap IGHV3-7*02 F 861 92.08 186/202 nt 91.58 185/202 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 5 8 9 5.8.9 [1.15.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 15 nucleotides (from position 20 in the user submitted sequence), (do not cause frameshift) ctctggattcctttttagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaacctcag +14856 JY8QFUQ01BWN4T productive Homsap IGHV3-66*02 F, or Homsap IGHV3-66*03 F 863 89.3 192/215 nt Homsap IGHJ4*03 F 195 89.58 43/48 nt Homsap IGHD6-25*01 F 1 8 7 11 8.7.11 [1.17.38.11] CARDGRGGDLDSW in-frame - tgtctgggttctccgtcagtttcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatctatgccgatggaagtacattctatgcagactccgtgaagggccgattcatcatctccagagacaattcaaagaacacgctcaatcttcaaatgaatagtttgagagttgacgacacggctgtgtattactgtgcgagagatgggcgcggcggtgaccttgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14857 JY8QFUQ01B1Q8U unproductive Homsap IGHV3-48*01 F 1085 99.54 217/218 nt 99.08 216/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 1 8 8 X 8.8.X [1.17.38.11] CASIFGSGSPWG#YYYGMDVW out-of-frame + in FR3-IMGT at codon 94 of V-REGION: 'C' (1 nucleotides at position 186 to 186 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcCctgagagccgaggacacggctgtgtattactgcgcctcgatttttgggagtggttccccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +14858 JY8QFUQ01BN0IG productive Homsap IGHV1-24*01 F 988 96.24 205/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame - ggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14859 JY8QFUQ01AOE9Z unproductive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKEEFDTGWTQPGD## out-of-frame - ctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactgggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14860 JY8QFUQ01A9Y7T productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14861 JY8QFUQ01DL5OF unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 997 96.71 206/213 nt 96.24 205/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.16.38.11] CASANYDYVWGELSL#DYW out-of-frame - stop codons in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 43 in the user submitted sequence), (cause frameshift) tctgggtggctccatcagtagttactactggagctggatccgcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14862 JY8QFUQ01C2RVY productive Homsap IGHV3-48*03 F 865 88.58 194/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDKGWSGYGMDVW in-frame - gcctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14863 JY8QFUQ01CC1F0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +14864 JY8QFUQ01BWUL4 unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14865 JY8QFUQ01CTC8T productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 876 90.19 193/214 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14866 JY8QFUQ01AUHKU productive Homsap IGHV3-74*03 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14867 JY8QFUQ01A2TC0 No results +14868 JY8QFUQ01C1LYN productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1057 99.07 214/216 nt 98.61 213/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [2.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14869 JY8QFUQ01B8RUV productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 937 92.24 202/219 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [2.17.38.11] CARGMATAESW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gcctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14870 JY8QFUQ01B56F9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 896 90.37 197/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + cctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14871 JY8QFUQ01CKHXI No results +14872 JY8QFUQ01A4XXA productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 94.47 205/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD4-17*01 F 2 8 7 11 8.7.11 [1.17.38.11] CAGHLLGDPFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) gttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatcatcctggtgactctgacaccagaCtacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaatcccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14873 JY8QFUQ01B4F4Q productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CVKDYGNCGGGRCYSIPLDYW in-frame + cctctggatttacctttagccgctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcattattgatgttaattctttcacatactacgcagactctgttcggggccggttcaccgtgtccagagacgattccaagaacacggtatatctgcaaatgaacagtttgagacccgacgacacggccgtttattattgtgtgaaagattacggtaactgtggtggtggtcgctgctattcgattccccttgactactggggccggggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14874 JY8QFUQ01AY1X8 No results +14875 JY8QFUQ01CEEUJ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRDDDTSGHYSLFKYW in-frame + gtctggattctcctttagtgcatatggcatacactgggtccgccagactccaggcaaggggctggagtgggtggctgttatgtattttgatggagttagaacattttatgcagactccgtgaagggccgattcaccctctccaaagactattccaagaacacggtgcatctgcaaatgaacagcctgcgagccgaggacacggctgtatattactgtgtgagagatgatgataccagtggtcactactctctgtttaaatattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14876 JY8QFUQ01BQZIL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 3 8 8 21 8.8.21 [1.17.37.11] CAKYVEGWSYTGGYYNSYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 67 of V-REGION: 1 nucleotides (from position 107 in the user submitted sequence), (cause frameshift) ttctggattcgcctttagccgttatgccatgacttgggtccgccagactccagggagggggctggagtgggtctcaggtctcagtggtagtggtgatagcacatacactcaaactccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggaggggtggtcatatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +14877 JY8QFUQ01BC11J No results +14878 JY8QFUQ01CUXC6 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 868 89.35 193/216 nt 87.5 189/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'T' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); tctggattcaGattttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtGcggtggtgttaattggaaTtgggggcagcgcaggttatgcagGtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14879 JY8QFUQ01BYI85 unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 950 93.12 203/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca +14880 JY8QFUQ01AWT13 productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*03 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAREWAASHFDHW in-frame + cctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatgaacagcctgagacctgacgacacggctgtatattactgtgcgagagagtgggcagccagtcactttgaccactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +14881 JY8QFUQ01APDAE No results +14882 JY8QFUQ01ALWLG productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + cctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14883 JY8QFUQ01BYEHM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARNELPWDTREYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggGggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14884 JY8QFUQ01A01ZH unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1115 100.0 224/224 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [2.17.38.11] CARSRTFYGSANY## out-of-frame - ctgtctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14885 JY8QFUQ01B2GMI productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 858 89.25 191/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [0.17.38.11] CARLGQLALDYW in-frame + gggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14886 JY8QFUQ01DOF6Y productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 882 89.86 195/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 9 7 12 9.7.12 [1.17.38.11] CAANLGHGSYFKYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); ctctggtgactccgtcagcagtgataactggtggagGttgggtccgccagaccccagggaaggggctggagtggattggagaaatctatcatgGgtgggaccaccaactacaatccgtccctcaagggtcgagtcaccttatcggtcgacaagtccaagaaccaattctctctgagaatgacctcttttaccgccgcagacacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14887 JY8QFUQ01AD2FI unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 940 93.06 201/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CARKGPQKRWLPTAM#DMDVW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggcccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +14888 JY8QFUQ01BH5J8 No results +14889 JY8QFUQ01CN5EM No results +14890 JY8QFUQ01CZ3D6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKAGYSSARTHMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggattcacctttagcaatttttgcatgacctgggtccgccaggctccagGggaaggggctggagtgggtctcagttgtgagtggtagtggcgatagaacagactacgcagactccgtgaagggccggttcactatctccagagacaattccaagagtacactattcctgcaaatgcacagcctgagagtcgaggacacggccgtatattactgtgcgaaagctggatatagtagtgcgcgaacccacatggacgtctggggccaaggggtcgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14891 JY8QFUQ01BEXBU productive Homsap IGHV3-72*01 F 1093 98.67 222/225 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-15*01 F 1 8 10 8 8.10.8 [2.17.38.11] CLRPPRYDPW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gcctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14892 JY8QFUQ01B8536 No results +14893 JY8QFUQ01CL9EO productive Homsap IGHV4-4*07 F (see comment) 683 80.0 172/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-9*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARESTNSIGDPRHLDSW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01CL9EO ; 8 AA in Homsap_IGHV4-4*07), and low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggccccatcaacacacatgacttctattggacgtggatccggcagtccgccgggaggggactggagtggctcggacgtgtctatatgaatggcattagtgaccacaatccagtcttcactagtcgtctcaccatgtccattgacacgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcggactcggccctatattactgtgcgagagaaagtactaattcgattggcgacccgagacaccttgactcttggggccagggaaggttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +14894 JY8QFUQ01ASVBI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtgcgtggaactcag +14895 JY8QFUQ01CEP8T No results +14896 JY8QFUQ01C1J8G productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 938 91.86 203/221 nt 91.4 202/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDCDSGECNFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cgccctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaAaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14897 JY8QFUQ01CPX03 productive (see comment) Homsap IGHV3-7*03 F 864 88.94 193/217 nt 87.56 190/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 77 of V-REGION: 'G' (1 nucleotides at position 136 to 136 in the user submitted sequence), (cause frameshift); ctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaagGgggctggagtgggtggccaacattcacgaagaAgggaagtgaaaagaattatgtggactctgtgaagggccggttcGtccatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14898 JY8QFUQ01BJYH6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 841 87.96 190/216 nt 87.5 189/216 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD2-8*01 F 1 8 8 19 8.8.19 [1.16.38.11] CAKVFQVSGEHHFYYYGMNAW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcatctttagtaattatgccatgagttgggtccgccaggccccagggaggggctggagtgggtctcaactatcagtgccaatggagacaacacatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacagtgtatatgcaaatgaacagcctgaaagccgaggagacggccgtctatcattgtgcgaaagtcttccaggtgtctggcgaacatcacttctactactatggtatgaatgcctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14899 JY8QFUQ01DGXOJ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactacctggggccagggaaatcctggtcaccgtctctcagcctccacaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14900 JY8QFUQ01B2S3P productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame + ctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14901 JY8QFUQ01C4TB9 unproductive Homsap IGHV3-7*01 F 836 87.91 189/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CARVGGDYNDDHKYYLDY## out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) gctctggattcaTcatttggacactattggatgagttgggtccgccagattccagggaagggtctggagtgggtggccaacatacaacaagataggaagaattattatctggactctgtgaagggccgatttaccatctccagagacgacgccgggaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatatattactgtgcgagagtgggtggtgactataacgacgaccacaagtattaccttgactactggggccgggggagtcctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +14902 JY8QFUQ01AK176 productive Homsap IGHV3-7*03 F 826 87.79 187/213 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [X.17.38.11] CTRRGFMDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ggattcacttttagtgactattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14903 JY8QFUQ01BH5QO productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +14904 JY8QFUQ01CBSLO productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 794 84.62 187/221 nt 83.71 185/221 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFESW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); tttccggtgactccatcaccagtactaattattactggggctgggtccgccagTcccccagggaagggtctggagtggattggaagtgtctattatCggggggacccagtacctcaacccgtctctccacaatcgagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtcttttggagtgataattgttaactactttgagtcctggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14905 JY8QFUQ01BDMY2 unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F or Homsap IGHV1-69*01 F or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F 86 57.53 42/73 nt 56.16 41/73 nt X X X X.X.X [24.X.X.X] null - No rearrangement found in FR1-IMGT, from codon 7 of V-REGION: 3 nucleotides (from position 90 in the user submitted sequence), (do not cause frameshift) agttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgctctcggaggtgctcctggagcagggcgccagggggaagaccgatgggcccttggtggaggtgacgaagccaccagaga +14906 JY8QFUQ01BURWS productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) gcctcctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14907 JY8QFUQ01CAQ0D unproductive (see comment) Homsap IGHV4-61*01 F 952 92.34 205/222 nt Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD3-16*01 F 2 10 7 X 10.7.X [2.17.38.11] CTKGGIHL*Q#PW out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gtctctggtggctccatcagcggtagtactaactactggagctggattcggcagcccccagggaagggactggaattcattgggtatatctattccagtgggaggaccaactacaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccagttctccctgaggctggcgtctgtgaccgctgcggacacggccgtgtattactgtacgaagggggggatacacttatgacagcccgtggggacaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14908 JY8QFUQ01AUKYE productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 849 87.0 194/223 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-22*01 F 2 8 10 11 8.10.11 [1.17.38.11] CTWDSTGYFRLTW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggactcactttcagtgacgcctggatgacctgggtccgccaggttccagggaaggggctggagtgggttgcccatattagatggaactctgatgactggaccacagactacgctactcccgtgaagggcagattcaccatctcaaaagatatttcagagaacacgctgtatctacaaatgaacagcctgataagcgaggatacaggcgtttattactgtacctgggacagcactggttattttcggcttacctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgggtccagggcttcttccccca +14909 JY8QFUQ01CV1WC No results +14910 JY8QFUQ01C0J50 unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1045 95.61 218/228 nt 95.18 217/228 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD1-26*01 F 1 10 9 X 10.9.X [2.17.38.11] CTRGSSRGGRYDENYYELDF## out-of-frame + in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); tctccgggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaAagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggcccagggaaccctggtcaccgtctcctcagcatcccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccg +14911 JY8QFUQ01B8GKK productive (see comment) Homsap IGHV4-61*02 F 906 90.45 199/220 nt 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERSISIGGARELDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'GTTTATAGTAGT' (12 nucleotides at position 87 to 98 in the user submitted sequence), (do not cause frameshift); ctctggcggccccatcaacagtggtcgttattactGggacctggatccggcagcccgccgggaaggggctggagtggatcggacgtGTTTATAGTAGTctttatacaagtgggaccaccgactacaatccctccctcaggagtcgagtcaccatgtcagtagacacgtccaagaagcagttctccctgaagttgacctctgtgaccgccgcagacacggccgtatattactgtgcgagagaacgtagtatttcgattggcggagcgagagaacttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14912 JY8QFUQ01A9WTH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 864 88.94 193/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'TC' (2 nucleotides at position 52 to 53 in the user submitted sequence), (cause frameshift); tccgggattcacctttagtagtttctGggatgcactggGgtccgccaagttTCccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14913 JY8QFUQ01AM4ZR productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +14914 JY8QFUQ01BJP01 productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14915 JY8QFUQ01AX3WD productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14916 JY8QFUQ01APXXU unknown (see comment) Homsap IGHV3-7*03 F 135 51.69 107/207 nt 8 8 X 8.8.X [1.17.34.X] null + No rearrangement found ctctggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14917 JY8QFUQ01C2GMG productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +14918 JY8QFUQ01C71ZZ unproductive (see comment) Homsap IGHV4-4*07 F (see comment) 557 73.49 158/215 nt 73.02 157/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARVRDAYTAGHFDS* in-frame - stop codons Low V-REGION identity (73,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'CT' (2 nucleotides at position 36 to 37 in the user submitted sequence), (cause frameshift); tctctggtgactctgtcactatgtcttattggggcCTgggatacgtcagcccgccgggggaggcctggagttaattggacgaacttctgccagtccaaaagttacctacaatccctccctcaggagtcgagccaccatattcgaagacacttcaaagaatcaacttatcttgaaattggcctctgtgaccgccgcggacacggccatctactactgtgcgagggtccgtgatgcctacaccgctggacactttgactcctgaggcccgggaaccctggtcaccgtctcttcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14919 JY8QFUQ01A6B0R No results +14920 JY8QFUQ01BGP7O No results +14921 JY8QFUQ01B6W83 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtGggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14922 JY8QFUQ01AL16A unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGHSYYVSSGPDY* in-frame - stop codons cctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactagggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14923 JY8QFUQ01AO23Y productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 7 8 15 7.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift) gtctggatcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14924 JY8QFUQ01CY4HO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 797 85.32 186/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaacctcaatacctttggcatgaactgcgtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14925 JY8QFUQ01DK0ZZ productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [1.16.38.11] CARVIPGRGNYAFDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) ctctggattcgactttggtagttattggatgagttgggtccgccagctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14926 JY8QFUQ01AL2Y7 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1034 98.14 211/215 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14927 JY8QFUQ01APVLM No results +14928 JY8QFUQ01DQLS5 unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ2*01 F (see comment) 76 60.38 32/53 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagataggcgtgggtatagttatgaaatggactactgggggacagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14929 JY8QFUQ01BJDP3 productive (see comment) Homsap IGHV3-48*01 F 1090 100.0 219/219 nt 98.17 215/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.17.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); gcctctggattcaccGttcagtagctatagcatgaactgggtccgGccaggctccagggaaggggctggagtgGggtttcatacaGttagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14930 JY8QFUQ01C283O No results +14931 JY8QFUQ01AFT98 unproductive Homsap IGHV3-30*01 F 869 88.99 194/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGSHQSE#YGLDVW out-of-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcgggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14932 JY8QFUQ01CG9V4 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F (see comment) 669 78.97 169/214 nt 78.04 167/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (78,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tggattcaccttcagtagctactggatgcattgggtccgccaGggctccagggaAaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14933 JY8QFUQ01CESL5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame + tctggattcactttccacacctactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14934 JY8QFUQ01DE51M unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 885 88.34 197/223 nt 87.0 194/223 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD6-19*01 F 1 10 7 X 10.7.X [2.17.38.11] CTNDHSMAVSAKHAF*CL# out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'AA' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift); tgtctctggtgcctccGatgagcaCgtagtgcatactactggggctgggtccgccagAAcccccgggaagggggccggagtggattgggagtgtctactatggtgggagcacctactacaacccgtccctcaagagtcgggcctccatttctgtcgacacgtccaggaacgagttctccctgaggctgaactctgtgaccgccacagacacggctatgtattactgcacgaacgaccattcaatggcagtctctgctaagcatgctttttgatgtttgggggtccagggacaatggtcaccgtctcttcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14935 JY8QFUQ01ABJ9P unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 489 82.98 117/141 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (82,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag +14936 JY8QFUQ01B8J0R productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame + tttcgggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14937 JY8QFUQ01CSXI9 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14938 JY8QFUQ01BTIFU unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 123 50.95 107/210 nt 8 8 X 8.8.X [1.17.35.X] null - No rearrangement found cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14939 JY8QFUQ01B3XWC unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 861 90.05 190/211 nt 89.1 188/211 nt Homsap IGHJ5*01 F 102 66.67 34/51 nt Homsap IGHD5-18*01 F 1 7 7 X 7.7.X [0.17.38.11] CAREFRAPSLARYGMDV## out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) cggggttcagcgtcagtaataactcatgacctgggtccgccaggttccagggaAaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagtctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctgggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14940 JY8QFUQ01CDDA1 productive Homsap IGHV3-9*01 F 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 211 82.26 51/62 nt Homsap IGHD6-6*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKGARSSLYHALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcacctttgatgattctgccatgcactgggtccggcaagttccagggaagggcctggagtgggtctcaggtattatttggagtagtgctaacataggctatgcggactctgtaaagggccgcttcaccatctccagagacaacgccaagaattccctttatctacaaatgaacagtctgagagtagaggacacggccttgtattattgtgcaaaaggggcaaggtcgtccctctatcacgctttggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +14941 JY8QFUQ01AQ85X productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARHYDSSGYYSDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagcacttatagcatgaactgggtccgccaggCccccagggaaggggctggagtgggtcgcattcatgagtagtactagtaggtatatatattatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaatagcctgagagccgaggacacggctgtctattactgtgcgaggcactatgatagtagtggttattacagtgatgcttttgatatctggggccaagggacaatggtcacggtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +14942 JY8QFUQ01A7C1U productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggGggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14943 JY8QFUQ01AQ8IY unproductive Homsap IGHV3-7*01 F 977 94.5 206/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDPYNGGGYGAFDI## out-of-frame + cctctggattcacctttagtaataattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacatcaagcaagatggaagtgagaaagtctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgctaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagacccctataatggtggtggttatggtgcttttgatatctgggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14944 JY8QFUQ01DJI2E productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.74 200/218 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CGKPIVGATGREMPVSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagcaactatgccatgaactgggtccgccaggttccaggggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14945 JY8QFUQ01DJP18 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARAGYCNNGVCYSSYFDFW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccggggaaggggctggtgtgggtctcacgtatgaatagtgatggcagtgacataaggtacgcggactccgtgaggggccgattcaccatctccagagacaacaccaagaacacgctgtatctacaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagcgggatattgtaataatggtgtatgctactccagttactttgacttctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +14946 JY8QFUQ01C6IY1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1000 95.43 209/219 nt 94.98 208/219 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [2.17.38.11] CAKDKWYYDSSGYQYYLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 16 to 17 in the user submitted sequence), (cause frameshift); gcctgtggattccccCTtttagcaactatgacatgaattgggtccgccaggctccagggaaggggctggagtgggtctccggtattagtggtagtggcggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctggatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagacaaatggtactatgatagtagtggttatcaatactaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14947 JY8QFUQ01CQPSE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14948 JY8QFUQ01DQP4Z No results +14949 JY8QFUQ01AES3L unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +14950 JY8QFUQ01C57G2 unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1013 94.27 214/227 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 10 9 X 10.9.X [1.17.38.11] CARRALDSSGHYIDI## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggcctcgagtggctgggaaggacatactacaggtccaagtggtattatgactatgcagtgtctgtccaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagctgaattctgtgaccgccgcagacacggctgtgtattactgtgcgagacgcgcattagacagtagtggtcattacattgacatctgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14951 JY8QFUQ01AG93B productive (see comment) Homsap IGHV3-23*05 F 831 87.85 188/214 nt 86.92 186/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 7 7 10 7.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) cctctggatcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14952 JY8QFUQ01AC0UT productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [2.16.38.11] CAGGRGWLIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift) gcctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccgaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14953 JY8QFUQ01B830G unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt 86.24 188/218 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [2.17.37.11] CMNELGYCSGR## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 89 of V-REGION: 1 nucleotides (from position 172 in the user submitted sequence), (cause frameshift) gcctctggattcacAttttaggagtcatatgatgagttgggtccgccagactccagggaaggggctggaatgggtctcaagtattcgagccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaactccaagaacacgatgtattgcaaatgcacagcctgagagtcgacgacacggccgtatactactgtatgaacgaactcggatattgtagtggtcggggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14954 JY8QFUQ01BM3TF productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ6*02 F (see comment) 157 72.58 45/62 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.38.11] CARGHRNPGVWDLGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); ctacagtgggtccttcagtggttacctctggacctggatccgccagtcccccgggaaggggctggagCtggattggagaaattaattatagtgggagaaccaactacaacccgacccttgagagtcaagtcaccatttctgtagacacgtccaagaaccaattctccctgaagcttacctctgtgaccgccgcggacacggctgtctattactgtgcgagaggtcacagaaatccgggagtttgggacctcggtctggacgtctggggccaggggaccacggtcatcgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14955 JY8QFUQ01B0222 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 782 84.65 182/215 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARGEECRSGSCYSVWFDPW in-frame + Low V-REGION identity (84,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctggtgggtccttaagtgactcctactgggcctggatccgccagcccccagggaagggcctggagtacattggggagatcagtcatgatggtagaaccatgttcaattggtccctcaagagtcgactcaccatctcagtagacacgtccaagaatcaattctccctgagattgacctctgtgaccgccgcggacacggctgtttattactgcgcgagaggcgaggaatgtcggagtggaagttgctactccgtttggttcgacccctggggccagggagcccaagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14956 JY8QFUQ01AC5LX No results +14957 JY8QFUQ01AAQL2 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 925 90.99 202/222 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 1 10 7 12 10.7.12 [2.17.38.11] CAWGWFGLNYFDYW in-frame - gtctctggtggctccgtcagaagtaccagttactactggggctggatccgccagcccccagggaaggggctggagtggattagtaacattcattctagtggaaccacctactacaacccgtccctcaacagtcgagtcaccatgtccgtaaacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcggacacggctgtatattactgtgcatgggggtggttcggactgaactactttgactactggggcccgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14958 JY8QFUQ01CGPNS productive Homsap IGHV4-61*02 F 857 87.78 194/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 11 10.7.11 [1.17.38.11] CARSGWDNQFDFW in-frame - tctctggtgtcgccaccagtagtggcacttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaacccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14959 JY8QFUQ01B7CJU unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 985 95.37 206/216 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD2-8*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDGQRYCSNGVCSSFFDS## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +14960 JY8QFUQ01DG11T productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14961 JY8QFUQ01BHKRI No results +14962 JY8QFUQ01ACKNS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14963 JY8QFUQ01CUXMH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14964 JY8QFUQ01AH1G7 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 864 88.94 193/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDREPFYDFWSGFGWSGWTS# out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cactggattcaccttcagttcctacaccatggaatgggtgcgccaggctccagggaaggggctggagtggctctcctcaattagtagtagtggtagttccatctcctacgcagactcagtgaggggccgattcaccatttccagagacgacgccgggaactcactgcatctgcaaatgaacagcctgagagtcgaggacacggctgtttattattgtgcgaaagatcgtgaaccgttttacgatttttggagtggttttggttggtccggatggacgtctggggccagggaccacggtcatcgtctcctcaagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14965 JY8QFUQ01B1W7W No results +14966 JY8QFUQ01BNXLT productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [1.17.38.11] CARGDGYNFGGLDYW in-frame + ctctggattcaacttcataggttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactccgtgaggggccgatccatcatttccagagacgattctaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14967 JY8QFUQ01A1AWW unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 233 57.65 113/196 nt 8 8 X 8.8.X [1.17.31.X] null + No rearrangement found Low V-REGION identity (57,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaccattggatgaactgggtccgccaggatccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggcaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14968 JY8QFUQ01DT42Q productive (see comment) Homsap IGHV3-48*01 F (see comment) 759 84.11 180/214 nt 83.64 179/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggttcttcccc +14969 JY8QFUQ01DA7JF productive Homsap IGHV3-72*01 F 949 91.56 206/225 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-15*01 F 1 8 10 11 8.10.11 [2.17.38.11] CTPWWRGGYFDYW in-frame - gcctctggactcaccttcagtgcccagtacttagactgggtccgccaggctccagggaagggactggagtgggttggccgtattagaagcaaaactaacagttacaccacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaaccatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtaccccgtggtggcggggaggttactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14970 JY8QFUQ01C36PX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 813 86.92 186/214 nt 86.45 185/214 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKESLVRGVISYYFDDW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) ctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggtttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctggttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +14971 JY8QFUQ01BPUIM productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1071 99.54 216/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14972 JY8QFUQ01ANO0O No results +14973 JY8QFUQ01CKEMG productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14974 JY8QFUQ01CPBOG productive Homsap IGHV1-24*01 F 988 96.24 205/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame - ggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14975 JY8QFUQ01CVWCY productive Homsap IGHV4-61*02 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-8*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARGYCSNAVCYQIMNW in-frame + tctctggtggctccatcagcagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggccgtgtattactgtgcgagaggatattgttctaatgctgtatgctatcaaatcatgaactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgcctgctccaggagcacctctgggggcacancggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14976 JY8QFUQ01AOFPE productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSGPSGYARYESMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14977 JY8QFUQ01BYD6M productive (see comment) Homsap IGHV3-11*01 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [2.16.38.11] CADIKLGDWCFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 42 in the user submitted sequence), (cause frameshift) gcctctgaaatcaccttcagcgaccactacatgagctggatcgccaggctccaggaaaggggctggaatggatttcatatattagcaccagtggtaatatgatctattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaggtcgatgtatttgcagatgaacagtctgagagccgaggacacggccgtctatttctgtgccgatataaaactgggtgactggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14978 JY8QFUQ01C256P productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14979 JY8QFUQ01BS0TJ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 931 92.59 200/216 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [2.17.38.11] CARAPRTATLLDPW in-frame - gtctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtatattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14980 JY8QFUQ01AVO1E No results +14981 JY8QFUQ01AQYA8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14982 JY8QFUQ01CYLRD productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggtaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +14983 JY8QFUQ01CXQJM unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 832 87.5 189/216 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKSPLSVAGTRQNWFD#PG out-of-frame - ctgacttgcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctgggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14984 JY8QFUQ01CBXPQ productive (see comment) Homsap IGHV4-4*07 F 828 87.1 189/217 nt 86.64 188/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [2.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); tgtctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgCaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14985 JY8QFUQ01DN616 No results +14986 JY8QFUQ01AC3MC unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 804 86.45 185/214 nt 85.98 184/214 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD1-26*01 F 2 8 7 X 8.7.X [1.17.37.11] CATLRGGYFRLL# out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaaccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagaggggggtactttcgactactggggccgggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14987 JY8QFUQ01AHP8Y productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 7 12 8.7.12 [1.17.38.11] CARAPGWMNPFDFW in-frame - tctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14988 JY8QFUQ01A8SUT productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 98 of V-REGION: 'T' (1 nucleotides at position 199 to 199 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgaTcgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14989 JY8QFUQ01CJ5PW productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +14990 JY8QFUQ01BBZP7 No results +14991 JY8QFUQ01A17OX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 842 87.61 191/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CMNEFGYCSGG# out-of-frame + gctctggattcacttttagcagccatatgatgacttgggtccgccaggctccagggaaggggctggaatgggtcgcaagtattcgtgccagtggtggtaggacacactacgcagactccgtgaagggccgctccaccatctccagagacaactccaagaacacgttgtatttgcaaatgtacagtctgagagtcgaggacacggccttatattattgtatgaacgaattcggatactgtagtggtgggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +14992 JY8QFUQ01CH6SP productive Homsap IGHV3-9*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKPGVVGLVPYYFDYW in-frame - ctctggattcacctttgatgattatgccatgcactgggtccgcaagcgtccagggaagggcctggagtgggtctcaggtattagttggaatagtggtagcataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagctgaggacacggccttgtattactgtgcaaaaccgggggtagtgggtctagttccgtactactttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +14993 JY8QFUQ01C5UCI unproductive Homsap IGHV3-11*04 F 919 90.87 199/219 nt 89.95 197/219 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [2.17.38.11] CASGGVTEAHY## out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 128 to 128 in the user submitted sequence), (cause frameshift); gcctctggaGttcaccttcagtgactactacatgagttggatccgccaggctccagggaaggggctggagtgggtttcatacattggtgttggtactggtggcatatactacgcagactctgtgaggGggccgattcaccatctccagggacaatgccgagaactcagtgcatctgcaaatgaacagcctgagagacgacgacacgggtgtttattactgcgcgagcggaggggtgacagaggctcactactgggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc +14994 JY8QFUQ01AS3DP unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 105 100.0 21/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattcactttcagtaa +14995 JY8QFUQ01AZJWC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +14996 JY8QFUQ01DVY3B productive (see comment) Homsap IGHV3-9*01 F 820 86.3 189/219 nt 85.39 187/219 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD5-24*01 ORF 3 8 8 17 8.8.17 [2.17.38.11] CVKDRKAGGYNLLDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcgacgactatgtcatgcattgGggtccggcaagttccagagaggggcctggagtgggtcgcaggcattaatCggggaaagtaatagttttggctctgtggactctgtaaagggccgattcaccatctccagagacaaggccaagaataccctgtatttgcaaatgaatagcctgagagttgaggacacggccttgtattattgtgtgaaagatagaaaagctggtggctacaatctgttggatgcttttgatatctggggccaagggacaatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14997 JY8QFUQ01BZIWN No results +14998 JY8QFUQ01DSDDA productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*04 F or Homsap IGHV3-49*05 F 975 93.27 208/223 nt 92.38 206/223 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 10 17 8.10.17 [1.17.38.11] CTRDNPPLRSLEWLPFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 131 to 131 in the user submitted sequence), (cause frameshift); ctctggattcaacttcggtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcAaaagctgatgatgggacaacagaatacgccgcgtctgtgaaAaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +14999 JY8QFUQ01BVMDG productive Homsap IGHV4-39*02 F (see comment) 776 83.71 185/221 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD2-15*01 F 2 10 7 19 10.7.19 [1.17.38.11] CARHLTNSDVVHHFYSGVDVW in-frame - Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgcctccatcagtaatgataattatttctgggcctgggtccgccagtccccagggaagggtctgcagtggattggcagtatgtattatagtgggggcaccttttacgacccgtccctcaagggtcgaatcaagttgtccgttgacgtgtcgaagagccacttcctcctgaacctgacctctgcgaccgccgcagacacggctgtctattactgtgcgaggcatttgaccaactcagatgtggtccatcacttctactccggagtagacgtctggggcctcgggaccacggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15000 JY8QFUQ01AZ1TF No results +15001 JY8QFUQ01BX3ZQ No results +15002 JY8QFUQ01BFNOC productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 983 94.12 208/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 164 81.63 40/49 nt Homsap IGHD2-21*02 F 3 8 8 7 8.8.7 [2.17.38.11] CARMTDDFW in-frame - Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tagtctctgggttcaccctcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggttgcatacattagtagtagtggtagcaccataatctacgcagactctgtgaagggccgattcaccatctccagagacagtgccaagagctcactgtatctgcaaatgaacagcctgggagtcgaggacacggctgtgtattactgtgcgagaatgacagacgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15003 JY8QFUQ01A3YXB No results +15004 JY8QFUQ01BRNJL productive Homsap IGHV3-9*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + ctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15005 JY8QFUQ01BIKN4 No results +15006 JY8QFUQ01CIWSW unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15007 JY8QFUQ01AOFCE productive Homsap IGHV3-30*01 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [2.17.38.11] CAKDELPWDTIEYYFDYW in-frame - aggcctctggattcaccttcaatacctattctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15008 JY8QFUQ01BI38O productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccacaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactca +15009 JY8QFUQ01BPGN6 productive (see comment) Homsap IGHV3-7*02 F 907 92.02 196/213 nt 91.55 195/213 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [0.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 8 in the user submitted sequence), (cause frameshift) tggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15010 JY8QFUQ01B9F39 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 732 82.71 177/214 nt 82.24 176/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.16.38.11] CARDWGGSFDRYYFDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 72 in the user submitted sequence), (cause frameshift) tccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15011 JY8QFUQ01DBDGW productive Homsap IGHV3-48*01 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15012 JY8QFUQ01BAXTU unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 1021 96.76 209/216 nt 96.3 208/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.16.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaagggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15013 JY8QFUQ01DM1DN No results +15014 JY8QFUQ01BRJOR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca +15015 JY8QFUQ01AXU9Q productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctggattcacctacagcagcGtatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15016 JY8QFUQ01A2G06 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 20 8.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15017 JY8QFUQ01CE15S No results +15018 JY8QFUQ01COPBQ No results +15019 JY8QFUQ01BU9D0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 84 62.75 32/51 nt 8 8 9 8.8.9 [1.17.38.11] CARDNYGDYWG (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccaggggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15020 JY8QFUQ01AD2B5 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15021 JY8QFUQ01AWSRO productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt Homsap IGHJ2*01 F 211 88.68 47/53 nt Homsap IGHD4-23*01 ORF 2 8 7 17 8.7.17 [1.17.38.11] CARFHDYGGYGFYYYSDFW in-frame + ctctggtggctccatcagtagtcattactggagctggatccggcagcccccaggggagggactggagtggattggctatatctctgacagtggaagcaccaattacaacccctccctcaagagtcgagtcactatatcagtagacacgtccgagaggcagatctccctgaagctgacctctgtgaccgctgcggacacggccgtatattactgtgcgagattccatgactacggaggttacgggttttactattactccgatttctggggccgtggcaccctggtcacggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +15022 JY8QFUQ01B6L95 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15023 JY8QFUQ01CBHBT productive (see comment) Homsap IGHV1-2*02 F 1002 96.73 207/214 nt 96.26 206/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 2 8 8 16 8.8.16 [0.17.38.11] CTRQRIGCGGDCYPGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); tggatacaccttcaccgGgctactatctgcactgggtgcgacaggcccctggacaaggacttgactggatgggatggatcaaccctaacagtggtggcacaaactatgcacagaagtttcagggcagggtcaccatgaccagggacacgtccatcagtacagcctacatggagttgagcagtctgagatctgacgacacggccgtgtattattgtacgagacaacggatcggctgtggtggtgactgctacccaggggactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15024 JY8QFUQ01BJ4MK productive Homsap IGHV3-48*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARVENYSDSGGSFDYW in-frame - cctctggattcaccttcagtagctatagcatgaattgggtccgccaggctccagggaagggactggagtgggtttcatacattagtggaagtagtaataccatgtactacgcagactctgtgaagggccgattcaccatctccagagacaatgcccagaattcactacatctgcaaatgaacaacctgagagacgaggacacggctgtgtattactgtgcgagagtggaaaattactctgatagtggtggttcgtttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15025 JY8QFUQ01CJN8G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcag +15026 JY8QFUQ01ACCKZ productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 904 91.2 197/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-7*01 F 3 8 7 15 8.7.15 [2.16.38.11] CIADLPDSAENYPFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 58 of V-REGION: 9 nucleotides (from position 90 in the user submitted sequence), (do not cause frameshift) agcctctggattcacttttagtggcgcctggatgagctgggtccgccaggctccagggaagggctggagtgggttggccgtgttagaagcggtgggacaacagactaccctgcacccgtggaaggcagattcaccatctctagagatgatcgaaaaaacacgttgtatctggaaataagtagcctgaaaatcgaagacacagccgtatattactgtatcgcagatttgcccgactcggcagagaactatccctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15027 JY8QFUQ01CS82O productive Homsap IGHV1-8*01 F 939 93.46 200/214 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [0.17.38.11] CARGYGYPNYYHYAMDVW in-frame + tggataccccttcgacagttatgatatcagctgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaacagtgggaatacagcctatgcacagaagttccagggccgagtcacgatgaccagggacacctccacaagcacagcctacatggaggtgagcagcctcagatctgaggacacggccgtctattactgtgcgcgcggttatggctacccaaactactaccactacgctatggacgtctggggccaagggtccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggcttcttccc +15028 JY8QFUQ01BFV6C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD2-21*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARGKMVSTGMDVW in-frame + Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) ctctggattcaactttaacagctttgccatgagctgggtccgccaggttccagggatggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaacgcactgtatctgcaaatgaacagcctgagggccgaggacacggccgtgtattactgtgcgcgagggaagatggtgagcaccggtatggacgtctggggccaagggaccacggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15029 JY8QFUQ01BKD4D No results +15030 JY8QFUQ01BFADJ productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15031 JY8QFUQ01C02I8 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 987 94.55 208/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + ctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15032 JY8QFUQ01DFEU1 productive Homsap IGHV1-8*01 F 948 93.93 201/214 nt Homsap IGHJ1*01 F 188 84.62 44/52 nt Homsap IGHD4-23*01 ORF 2 8 8 13 8.8.13 [0.17.38.11] CARGSLDYGGLPQHW in-frame + tggatacaccttcaccagttatgatatcaactgggtgcgacaggccgctggacaagggcttgagtggatgggatgggtgaaccctaatagtggtgccacaggctatgcacagaagttccagggcagagtcaccatgagcagggacacctccgaaagtacagcctacgtggagctgagcagcctgggatctgaggacacggccgtgtatttctgtgcgagaggctccctggactacggtggcctcccccagcactggggccagggcaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15033 JY8QFUQ01B0SGS productive (see comment) Homsap IGHV3-7*01 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [0.17.38.11] CVRGRDGVNFGEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctgggttcatctttagtagacattggatggcctgggtccgccaggctccagGggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15034 JY8QFUQ01B7ETG No results +15035 JY8QFUQ01AZU67 productive (see comment) Homsap IGHV3-9*01 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [2.17.38.11] CVKDMGRSNWRYFHYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'T' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); gcctctggattcacctttgatgattatgccatgcactgggtccggcaagttccagggaggggcctggaatgggtctcaggtatcagttggggtagtgctagtTatagcctatgcggactctgtaaaggggcgattcaccatctccagagacaacgccaggaactccctgtatctgcaagtggacagtctgagacctgaggacacggccttgtatcactgtgtaaaagatatggggagaagtaactggaggtactttcactattggggccagggaaccccggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +15036 JY8QFUQ01B0ETU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - agcctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15037 JY8QFUQ01BE9N9 productive (see comment) Homsap IGHV3-7*01 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgaaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15038 JY8QFUQ01AMLU0 No results +15039 JY8QFUQ01A9LQB No results +15040 JY8QFUQ01A0X2Q unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 748 82.65 181/219 nt 82.19 180/219 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [2.17.38.11] CARIWDSWSGA#FDVW out-of-frame - stop codons Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagctttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15041 JY8QFUQ01DLALM unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 931 90.22 203/225 nt 89.33 201/225 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD3-22*01 F 3 8 10 X 8.10.X [2.17.38.11] CTSRYYDPSGYWSD#PG out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 220 to 220 in the user submitted sequence), (cause frameshift); gtctctggggtcaccttcagtgacgcctggatgacctgggtccgccaggctccagggaAaggggctggagtgggttggccgtattagaagcagagttgatggtgggacagtggactacgctgcacccgtgaaaggcagattcaccatctcaagagatgactccaaaaacacactatatctacaaatgaacagcctgaaaatcgaggacacagccatgtaCtttctgcaccagtcgatactatgatcctagcggttactggtccgacccctggggccagggaacccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +15042 JY8QFUQ01AI5BM productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); tctctggcgactccatcagtggtcactactggaggctggatgagcagccccaggccaagggaGctgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15043 JY8QFUQ01DBROA unproductive (see comment) Homsap IGHV3-13*01 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ6*02 F 215 82.26 51/62 nt Homsap IGHD2-2*01 F 3 8 7 X 8.7.X [1.17.38.11] CGPVMLC*YHLWVTXT#AMDVS out-of-frame + stop codons in FR2-IMGT at codon 46 of V-REGION: 'CAGG' (4 nucleotides at position 51 to 54 in the user submitted sequence), (cause frameshift); ctctggattcaccttcattagctacgacatgcactgggtccgccaggctaCAGGcaggaaaaggtctggagtgaatctcatctattggaatttctggtgacatatactatccaggctccgtgaagggccgattcaccatgtccagaggaaatgccaagaactccttgtatcttcaaatgaacagcctgagagccgaggacacggatgtatattgctgtggccctgtgatgttgtgttagtaccacctgtgggtgactnccactgcgctatggacgtctcgggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15044 JY8QFUQ01AWMMA productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15045 JY8QFUQ01BLVPK unproductive (see comment) Homsap IGHV4-61*01 F 978 94.09 207/220 nt 93.64 206/220 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD1-26*01 F 2 10 7 X 10.7.X [1.17.38.11] CARGGPVGPTGI*SGT# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 67 of V-REGION: 'TATAATCCCCTG' (12 nucleotides at position 110 to 121 in the user submitted sequence), (do not cause frameshift); ctctggtggctccgtcagcagagatatttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatgtatcacagagggaacactaagTATAATCCCCTGtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtccggtggggcctactggaatttgatccgggactgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +15046 JY8QFUQ01CII1K unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*07 F (see comment) 762 84.83 179/211 nt 84.36 178/211 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD2-15*01 F 2 5 9 X 5.9.X [X.17.38.11] CIADTPTSSRQAFDY# out-of-frame - Low V-REGION identity (84,83% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 76 in the user submitted sequence), (cause frameshift) acccttttgacacctggatgaactgggtccgccagactccagggaaggggctggagtgggttggccgtattaaaacaaaattgagggcgagacaacagactacgcggccgccgtgagaggcagattcaccatctcaagagatgactccaaaaacacgctgtggctgcaaatgaatgacctgaagaccgacgacacaggcatatactactgtatagcggatacccccaccagtagtcgtcaagcttttgactattgggccagggagcccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagtacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15047 JY8QFUQ01ADMP0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15048 JY8QFUQ01B3PL9 No results +15049 JY8QFUQ01C17PP productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15050 JY8QFUQ01BTXGE unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt 91.24 198/217 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CANWLSGTHSKFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccCaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagaaccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactgggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15051 JY8QFUQ01BMGFT productive Homsap IGHV3-7*01 F 924 91.36 201/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [2.17.38.11] CATSPFTVTTGKDAYW in-frame - agcctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15052 JY8QFUQ01B7L1I productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDLTGYSSERNYW in-frame - ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15053 JY8QFUQ01AV3G5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + cctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15054 JY8QFUQ01CCKMG productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.37.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15055 JY8QFUQ01C9KPN productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 892 89.95 197/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) ggcctcctggattcacCctttggttattatggcatgactgggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15056 JY8QFUQ01BGR80 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15057 JY8QFUQ01BSZGO productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKVRSYYGLDHTFDIW in-frame - atctggaataacctttagtacgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacatgaagccagatggacgtgagacattttatgtggactctgtgaagggccgattcaccatctccagagacaatgccaggaactcactgtttctgcaaatggacagcctgagagccgaggacacggctgtatattactgtgcgaaagttcggagctactacggactagatcatacttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15058 JY8QFUQ01C3HAZ No results +15059 JY8QFUQ01CMYY7 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame - gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15060 JY8QFUQ01B0OGP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15061 JY8QFUQ01AREB7 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 914 91.28 199/218 nt 90.37 197/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'G' (1 nucleotides at position 193 to 193 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtccttcaaggccagggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaagGgccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15062 JY8QFUQ01DNJF4 unproductive (see comment) Homsap IGHV1-69*06 F, or Homsap IGHV1-69*10 F or Homsap IGHV1-69*14 F 804 86.45 185/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-8*02 F 1 8 8 X 8.8.X [0.17.38.11] CARGGKSPRRDIIQGGDC#DALDLW out-of-frame + stop codons tggagacaccttcagtagccaagccatcagctgggtgcgacaggcccctggacaaggacttgagtggatgggcgggatcatccctatttttgatatgacgaggtacccacagaggttcgagggcagaatcacgattaccgcggacacgtccacgaccacactttacatggaactgagcagcctgaggtctgaggacacggccgtgtatttttgtgcgagaggcgggaagagtcctcgtcgtgatattatacaggggggtgactgttgatgctcttgatctctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15063 JY8QFUQ01A672E No results +15064 JY8QFUQ01BG9T4 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctgaattcacttttagtacctatgtcataagttgggtccgccaggtcccagggaaggggctggagtgggtctcaagtattgttgatggtggtgatatcacacactacgcagactccgtgaagggccggttcaccatctccagagacgaatccaagaacactgtctatctgcaaatgaacagcctgagagccgaggacacggccgtgtactactgtacgaaggtggcgagtcaagtgatcatggctacaacctactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15065 JY8QFUQ01CPRKO productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1011 97.2 208/214 nt 96.26 206/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagctactaTtttgcactgggtgcgacaggCcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcgaggggacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaactgtggtcatcgcctgcctggtccagggcttcttccccc +15066 JY8QFUQ01B6AB0 No results +15067 JY8QFUQ01BBNXY productive (see comment) Homsap IGHV4-4*07 F 813 86.92 186/214 nt 86.45 185/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgCaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15068 JY8QFUQ01B6RJR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.16.38.11] CARFGPLTRPDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaagggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15069 JY8QFUQ01BIHY8 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 977 94.5 206/218 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD3-22*01 F 3 9 7 11 9.7.11 [1.17.38.11] CAGLLTTFGLQSW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcagcagtagtaactggtggacttgggtccgccagcccccagggaaggggctggagtggattggggaaatctatcatggtggaaacacctactacaacccgtccctcaagagtcgagtcaccatatcactagacaagtccaagaaccaattctctctgaacctgaactctgtgaccgccgcggacacggccatatattactgtgcgggacttcttacgacttttggactgcagagctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15070 JY8QFUQ01AVJSP No results +15071 JY8QFUQ01CGWS6 No results +15072 JY8QFUQ01A5G7U unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 856 88.13 193/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [2.17.38.11] CMNEFGYCSGG# out-of-frame - ggctctggattcacttttagcagccatatgatgacttgggtccgccaggctccagggaaggggctggaatgggtcgcaagtattcgtgccagtggtggtaggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgttgtatttgcaaatgtacagtctgagagtcgaggacacggccttatattattgtatgaacgaattcggatactgtagtggtgggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15073 JY8QFUQ01A465M productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt 83.94 183/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); gtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15074 JY8QFUQ01CC0PM unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGGSVGPPGG#FDHW out-of-frame - in FR3-IMGT at codon 97 of V-REGION: 'G' (1 nucleotides at position 195 to 195 in the user submitted sequence), (cause frameshift); tctctggattcaccttcagtagttactggatacactgggtccgccaagctccagggcaggggctggtgtgggtctcacgaattgatagttctgcgcgtctcatagcctacgcggactccgtgaagggacgattcaccgtctccagagacaacgccaagaacacggtgtatcttcaaatgaacagtctgagagccGgacgacacggctatttattactgtgcaagaggggggtcagtggggcctccaggtgggggtttgaccactggggccagggagccctggtcaccgtcttctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15075 JY8QFUQ01CG2GA productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15076 JY8QFUQ01ACHS4 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ2*01 F 211 88.68 47/53 nt Homsap IGHD4-23*01 ORF 2 8 7 17 8.7.17 [1.17.38.11] CARFHDYGGYGFYYYSDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagtcattactggagctggatccggcagcCccccaggggagggactggagtggattggctatatctctgacagtggaagcaccaattacaacccctccctcaagagtcgagtcactatatcagtagacacgtccgagaggcagatctccctgaagctgacctctgtgaccgctgcggacacggccgtatattactgtgcgagattccatgactacggaggttacgggttttactattactccgatttctggggccgtggcaccctggtcacggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15077 JY8QFUQ01BYPRW No results +15078 JY8QFUQ01BPZVR No results +15079 JY8QFUQ01ANTVH productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 858 89.25 191/214 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame + ctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +15080 JY8QFUQ01B7MS9 unproductive Homsap IGHV3-48*03 F 846 88.02 191/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDKGWSGYGMDV## out-of-frame + ctctgggttcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaaggggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +15081 JY8QFUQ01ASB4Q unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 766 83.11 182/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (83,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15082 JY8QFUQ01AUXHC No results +15083 JY8QFUQ01B6NTH productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagccttcaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +15084 JY8QFUQ01B8E6T productive (see comment) Homsap IGHV1-69*04 F, or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69*10 F or Homsap IGHV1-69*14 F 822 87.38 187/214 nt 86.45 185/214 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [0.17.38.11] CAIPFSSSSAWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); tggaggcaccttcagcagctatgtcatcagctggctgcgacaggcccctggacaagggcttgagtggatGgggacatgtcattcctatGctttggtgtatctaacctcgcgcagaggttccagggcagagtcacaataaccgcggacacatccacgaccacagcctacatggaggtgaccaagctgagatctgaagacacggccgtctattattgtgccataccattcagcagctcgtcggcctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15085 JY8QFUQ01DIBVI productive Homsap IGHV3-21*04 F 483 89.26 108/121 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 X 2 10 X.2.10 [X.X.38.11] CARAVSNQVDVW in-frame + ctctggattcgccttcaactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15086 JY8QFUQ01C40TJ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame + ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag +15087 JY8QFUQ01DMN6Y unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDPRDYCSGGYCL#GAFDIW out-of-frame - tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgtttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15088 JY8QFUQ01AKOFT productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaactc +15089 JY8QFUQ01AQTFU productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [1.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) gttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgattttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15090 JY8QFUQ01A6RAB No results +15091 JY8QFUQ01BN8PY productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15092 JY8QFUQ01DWXKU unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 702 82.21 171/208 nt 80.77 168/208 nt Homsap IGHJ3*01 F 160 80.0 40/50 nt Homsap IGHD6-25*01 F 3 8 7 X 8.7.X [1.16.37.11] CARGTRYNNGLD#FDVW out-of-frame - Low V-REGION identity (82,21% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 46 of V-REGION: 2 nucleotides (from position 50 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 69 of V-REGION: 2 nucleotides (from position 107 in the user submitted sequence), (cause frameshift) tcgagtgcctccatgatcagttactattggacctggattcggcagccccaggaagggactgagtggattggggacatctattcctttggaggcaccagatacaaccgtccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgctttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15093 JY8QFUQ01DSNAP unproductive Homsap IGHV3-7*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAISSGLLLDG#YW out-of-frame - ctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtgggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15094 JY8QFUQ01DPEDU unknown (see comment) Homsap IGHV3-23*05 F 97 54.81 57/104 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons ctctggattcgtctttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15095 JY8QFUQ01BJNIX productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ6*02 F 94 61.29 38/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'C' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); cctctggacgctccttgagaagctttggcatgcactgggtccCgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggcccaaatgggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15096 JY8QFUQ01CV2IT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDAVGLTRLFGDW in-frame + ctctggatttgtctttagtagatatgccatggcctgggtccgccaggctccagggcaggggctggagtgggtcgccagtattggcgggagtggtgataacacatactacgcggactccgtgaagggccggttcaccatctccagagacaactccaataacaaactgtttctgcaaatggacagtttgcgagccggggacacggccagatatttctgtgcgaaagatgcggtgggacttacccgactctttggtgactggggccagggaaccgtggtcagcgccgcctctgcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15097 JY8QFUQ01CLZ3J productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 819 86.64 188/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSGPSGYARYESMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggaggggcgtggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15098 JY8QFUQ01DPHAI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 813 86.92 186/214 nt 86.45 185/214 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.37.11] CAKLENSSGNEDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 99 of V-REGION: 2 nucleotides (from position 199 in the user submitted sequence), (cause frameshift) tctgaattaacgtttgatatatatgccatgacttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactggtagtggtgataatgcctactacgcagacttcgtgaagggccgattcgccatctccagagacaattccaagaacatgttgtatttgcaaatgaacaacctgcgaggcgaggacggccgtttattactgtgcgaaactggaaaatagcagtgggaatgaagactcctggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15099 JY8QFUQ01ASOC9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-18*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARVRGYSYGYEYW in-frame + cctctggattcactctcaggagctatatcatggactgggtccgccaggctccagggaaggggctggagtgggtcgcatccattagtagtaatagtgaatacatatattatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactctctctatctgcacatgaacagcctgagagccgaggacacggctgtctattattgtgcgagagtacgtggttacagttatggctatgagtactggggccagggaaccctggtccctgtctcctcagcatccccgaccagcccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +15100 JY8QFUQ01BXHCB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDGMMTFGGVIVPSRFFFDYW in-frame + ctctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtagcggtggaactacatattatgcagactccgtgaagggccggttcaccatttccagagacaactccaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgaaagatggaatgatgacgtttgggggagttatcgtccccagtaggttcttctttgactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15101 JY8QFUQ01AXM44 productive Homsap IGHV4-61*02 F (see comment) 713 80.54 178/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERGTTVGGASEFDSW in-frame + Low V-REGION identity (80,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctggtggccccgtcattattgatggttattactggacgtggatccgtcagcccgccgggaagggactggagtgggtcggacgtgtcaccagtcgtggggagaccaattacagttcctccctcaagagtcgaatcttcatgtcagtagacacgtctaagaatcaattctccctgaggtttaattctgtgaccgccgcagacacggccctatattactgtgcgagagaacgcggtactacagttggcggggcgagcgaatttgactcctggggccagggagtgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15102 JY8QFUQ01A1RGD unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARVGYGYRGIYFFDY## out-of-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccaatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15103 JY8QFUQ01ADT1K productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt 97.24 211/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15104 JY8QFUQ01C8WYY unproductive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSGFLLDG#YW out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGcctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtgggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcttcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15105 JY8QFUQ01AGUED unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARGDGYNFGGLDY## out-of-frame - ctctggattcaacttcataggttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactccgtgaggggccgatccatcatttccagagacgattctaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15106 JY8QFUQ01AYJVF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15107 JY8QFUQ01BR4RU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame + ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15108 JY8QFUQ01CE03L unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1004 95.87 209/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CVRGDYGGAPDITTT#YGLDVW out-of-frame - cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15109 JY8QFUQ01AW7T2 productive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctcaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactaccttccccgaaccggtgacggtgtcgtggaactcca +15110 JY8QFUQ01AGQ07 unknown (see comment) Homsap IGHV3-74*03 F 103 53.6 67/125 nt 8 8 X 8.8.X [1.17.7.X] null - No rearrangement found tctggattcaccttcagtagctactggatgcactgggtccgccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15111 JY8QFUQ01A2UEW unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 664 93.96 140/149 nt 93.29 139/149 nt 8 7 X 8.7.X [1.17.16.X] null - No rearrangement found in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatg +15112 JY8QFUQ01CPEFH productive Homsap IGHV3-72*01 F 962 92.41 207/224 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD7-27*01 F 1 8 10 10 8.10.10 [1.17.38.11] CVRDPFSSRGHW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gctctggattcatcctcagtgactaccacatggagtgggtccgccaggctccagggaaggggctggagtgggttggccgtagtagaaagaaagctaatagttacagtacagaatatgccgcgtctgtgaaaggcagattctccatttcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaatcgacgacacggccgtgtattattgtgtcagagaccccttctcaagtcggggccactggggccagggaaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15113 JY8QFUQ01AHKYB No results +15114 JY8QFUQ01BV8GM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDVSTRITMRVVVPALDYW in-frame - cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattagtgataatggtgacagcatattccacgcagactccgtgaagggccggttcaccatcaccagagacaactctaagaacatcctgtatctgcacatgaacagcctgagagccgaggactcggccgtatattactgtgcgaaggatgtttccacgcgtattactatgagagttgtggtgccagcccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15115 JY8QFUQ01C2BW5 unknown (see comment) Homsap IGHV3-69-1*02 P 1034 98.14 211/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - Rearranged sequence but no junction found however the closest V is a pseudogene The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctagattcaccttcagtgagtactacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattaggagtagtagtaccatatactacgcagactctatgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtttattactgtgcgagagacgcaatgaattcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15116 JY8QFUQ01BMPU3 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 885 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ4*01 F 96 66.67 32/48 nt 8 8 X 8.8.X [1.16.37.11] CVSDLAGQKGF (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 166 in the user submitted sequence), (cause frameshift) tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaagggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccaggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15117 JY8QFUQ01B5198 No results +15118 JY8QFUQ01AK22Q No results +15119 JY8QFUQ01CY5YI productive (see comment) Homsap IGHV3-7*01 F (see comment) 743 82.57 180/218 nt 81.19 177/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcgtctttactaatcattggatgagttgggtccgccaggccacaGgggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggGggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15120 JY8QFUQ01BGBOT unproductive (see comment) Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKARIYFSWFGELFP#FDYW out-of-frame + stop codons cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttcatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15121 JY8QFUQ01C33GJ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); tctggagttcagccttcagtagctactggatgcactggGgtccgccaagctccagggaaGggggctggtttgggtctcacgtgttaatggtgatgGggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15122 JY8QFUQ01CT7JH productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + ctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15123 JY8QFUQ01CQLFX No results +15124 JY8QFUQ01C39CV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 806 85.78 187/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaagccaaggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaac +15125 JY8QFUQ01B1UNP No results +15126 JY8QFUQ01CHUH6 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 839 86.88 192/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARRHYGEGLFDYW in-frame - tctttggtggctccatcaccaataataattacttctggggctggatccgccagcccccagggaaggggctggagtggattggggatgtccagtatagtgggagcacctactccagcccgtccctcaagaggcgggtcaccatgtctgtggacgtgtccaaaagtcaggtctccctgagactgagctctgtgaccgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15127 JY8QFUQ01BNTQN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 554 72.48 158/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (72,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15128 JY8QFUQ01C8I32 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 970 93.24 207/222 nt 92.79 206/222 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 2 8 10 14 8.10.14 [1.17.38.11] CTTDPRYFWGSGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); tctggattccctttcagcaacacctacatgagctgggtccgccaggctccagggaaggggctggagtggattggccgtattaaaagcaaaactgatggtgggacaatagaatacgctgcacccgtgaaaggcagattaaccatatcaagagacgattcaAaaaaacacgctgtatctgcatatgagcagcctgaagatcgaggacacagccgtgtattactgtaccaccgatccccgttacttttgggggagcgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15129 JY8QFUQ01B9CM1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARDRSGYSSFDYW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagatagaagtggttattcgagctttgactactggggccagggaaccctggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15130 JY8QFUQ01BDTPB productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 741 83.18 178/214 nt Homsap IGHJ6*02 F 179 77.05 47/61 nt Homsap IGHD2-15*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDKVISAGRDVW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BDTPB ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagtttcactggttttaccgtgatctgggtccgccaggctccaaggaaggggctggaatggatctcatccgtcactactaatggtctcacgtactacgcagactcagtagagggccgattcaacatctccagggacaacgccaacaatttagtgtttctgcaaatgaacagcctgagagtcgaggacactggtgtatattattgtgcgagagataaagtgatctctgccggacgggacgtctggggccaagggaccacggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15131 JY8QFUQ01CL0E6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame + ctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15132 JY8QFUQ01AYZZX productive Homsap IGHV3-11*01 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKDRGKSGSYGLDYW in-frame + tctggattcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtggattgcgtacatcagtagtagtggtgataccatatattacgcagactctgtgaagggccgattcaccatctccagggtcaacgcccagaactcactgtctctgcaaatgaacagcctgagagtcgacgacacggccgtgtattactgtgcgaaagatcgggggaaaagtgggagctatgggcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15133 JY8QFUQ01AVSZQ No results +15134 JY8QFUQ01BGEDN No results +15135 JY8QFUQ01BU28T unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 63 of V-REGION: 2 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtgaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15136 JY8QFUQ01A5JQQ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame + in FR2-IMGT at codon 51 of V-REGION: 'A' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggAagtgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggcccctggggctgcctggtcaagggactacttgcccccgaaccggtgacggtgtcgtggaaactc +15137 JY8QFUQ01BDC8O unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 981 94.93 206/217 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + ctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15138 JY8QFUQ01CBIA5 No results +15139 JY8QFUQ01DG2ZP productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15140 JY8QFUQ01DFE49 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame + gttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag +15141 JY8QFUQ01DTXBK No results +15142 JY8QFUQ01C583H productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 932 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15143 JY8QFUQ01C6ZD1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgagcagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15144 JY8QFUQ01AUVO3 No results +15145 JY8QFUQ01AR9ZY No results +15146 JY8QFUQ01BT0UP productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + cctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15147 JY8QFUQ01ADXNM productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +15148 JY8QFUQ01AVMZN productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 712 80.82 177/219 nt 79.0 173/219 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [3.17.38.11] CARLDGHFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 128 to 128 in the user submitted sequence), (cause frameshift); gtagtctctgggttcaccatcagtCacgtactccatgggcCtgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgGcagactccgtgaGgggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15149 JY8QFUQ01CDX4C productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [2.17.38.11] CAKLGVAATTWNFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift); ccgtctggattcacctttaccacctatgccatgagctgggtccGgccaggctccagggaaggggctggaatgggtctcaactattagtggtagcggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15150 JY8QFUQ01BG9X3 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15151 JY8QFUQ01CWFBZ No results +15152 JY8QFUQ01CR05V No results +15153 JY8QFUQ01BWOWC unproductive (see comment) Homsap IGHV3-9*01 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKRRVGDTSDWY#YFEYW out-of-frame + stop codons gcctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +15154 JY8QFUQ01DBALT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 974 93.67 207/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - cagcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15155 JY8QFUQ01DRZ7T productive (see comment) Homsap IGHV3-66*02 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.16.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcagtagcagcttcatgacttgggtccgccagctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggccaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15156 JY8QFUQ01BUJ4F productive (see comment) Homsap IGHV3-66*02 F 858 89.25 191/214 nt 88.79 190/214 nt Homsap IGHJ1*01 F 206 88.46 46/52 nt Homsap IGHD6-19*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAAVGVGSAVSFQYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); ctctggcttcaccgtcaataacaactacatgggctgggtccgccaggctccagggaaggggctggagtgggtctcgattatttattacggtgGgaaccacatattacgctgactccgtgaagggccgattcaccatctctagagacacctccaagaacacgttatttcttcaaatgaataccctaagaggtgaggacacggctgtgtactactgtgcggcagtcggagtgggaagtgcagtctccttccaatactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15157 JY8QFUQ01CPGWQ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15158 JY8QFUQ01BUZU5 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactca +15159 JY8QFUQ01APXBV productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggattcaccttcagtagctactggatgcactggatccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15160 JY8QFUQ01CNB3H No results +15161 JY8QFUQ01CZ23L unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 913 91.67 198/216 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15162 JY8QFUQ01CEEQK productive (see comment) Homsap IGHV1-2*02 F 795 85.98 184/214 nt 85.51 183/214 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-16*02 F 2 8 8 15 8.8.15 [0.17.38.11] CARHYCDTNGVCDFDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tggatacagcttcaccgacttttCatattcattgggtgcgacaggaccctggacaagggcttgagtggatggggtggaccaaccctaaaaatggcggcacgttcattacgctgaagtttcagggcagggtcactatgtccagggacacgtccatgaccacagtctatatggaaatgagcaggctgagatctgacgacacggccatttattactgtgcgagacattattgtgacaccaacggcgtctgtgattttgatatctggggccaggggacaaaggtcatcgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +15163 JY8QFUQ01CL2ZL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + cctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15164 JY8QFUQ01BY1VQ No results +15165 JY8QFUQ01BH1QX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARDGEWEMLDHW in-frame + ctccggattcaccttcagtaggtattggatgtattgggtccgccaagctccaggcaaggggctggtgtgggtctcacgcattaaaagtgatgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacatatttttgtgcaagagacggggagtgggagatgcttgaccactggggccagggagccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgcagctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15166 JY8QFUQ01B9C4B productive Homsap IGHV3-66*02 F 898 91.55 195/213 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 7 13 8.7.13 [1.17.38.11] CASVGVGATVAFQYW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) tctggattcaccgtcagtgatagttacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcgattatttataggggaggtaccacatattatgccgactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctatatcttcaaatgaacaccctgagaggtgaggacacggctctatattactgtgcgagcgtcggagtgggagctacagtcgcctttcaatactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15167 JY8QFUQ01B2FOY productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1075 100.0 216/216 nt 99.54 215/216 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD5-12*01 F 2 8 7 12 8.7.12 [2.17.38.11] CARSGLRGYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttactacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagatctgggctacggggctactactttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15168 JY8QFUQ01DH9XO unknown (see comment) Homsap IGHV3-7*01 F (see comment) 756 82.95 180/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggagtcacctttagtgactattggatgagctggatccgccaggctccagggaaggggccggagtgggtggccaacatagagcaagatgggagtgagataaattatgtggactctgtgaagggccgattcaccatctccagagacaacaccgagaatgcactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15169 JY8QFUQ01A8RE4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 895 90.74 196/216 nt 89.81 194/216 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD5-12*01 F 2 7 8 12 7.8.12 [1.17.38.11] CGKQLGPIKGLTTG in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift) ctctggattcaccttagtagttctggcatgtattgggcccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatgccacGaaattacgcagactccgtgaagggccggttcaccatctccagagacaactccatgaacacactgtatctgcaaatgaacagcctgggaaccgatgacacggccttatattactgtggaaagcaattggggcccataaaggggctgactactggggccagggggaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15170 JY8QFUQ01BNBBX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 992 94.57 209/221 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [2.17.38.11] CVRRGMVAGRYDAFDIW in-frame - cagcctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15171 JY8QFUQ01BY3HN productive Homsap IGHV3-30*01 F 878 89.45 195/218 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [1.17.38.11] CACGHMRDGYDVW in-frame + cctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +15172 JY8QFUQ01AT5L5 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15173 JY8QFUQ01CYPQ3 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1007 96.74 208/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAREDGSGRRHFDYW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccaggaaagggactggagtggattgggtatatcttttacactgggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15174 JY8QFUQ01ARSJK productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15175 JY8QFUQ01DMG2N No results +15176 JY8QFUQ01BGQRX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcactccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15177 JY8QFUQ01CWYFO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-14*01 ORF 3 8 8 19 8.8.19 [1.17.38.11] CARIIPYDPRTDYYYYGMDVW in-frame + cctctggattcagcttcagtaattatatcatgacttgggtccgccaggccccagggaaggggctggagtgggtctcatctattagtggaagtagtagtaacatattctacgcagactcaatgaagggtcgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaataatcccgtatgacccgaggaccgactattattactatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +15178 JY8QFUQ01C4MIT unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 719 85.28 168/197 nt 84.77 167/197 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) tctgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +15179 JY8QFUQ01CT7D5 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARKRVPGGTFYG#DYW out-of-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatgggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15180 JY8QFUQ01CKGY7 unproductive (see comment) Homsap IGHV3-48*03 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame + stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); ctctggattcacctttactagttaCagttttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15181 JY8QFUQ01B6ER7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15182 JY8QFUQ01C9LNB productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1025 97.67 210/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARGGGYYFVAIDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgaggacgtgtcatcgcctgcctggtccagggcttcttccccca +15183 JY8QFUQ01C22YF No results +15184 JY8QFUQ01B6JCZ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +15185 JY8QFUQ01BR6MY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD1-26*01 F 3 8 8 11 8.8.11 [2.17.38.11] CLKDHRGNYFDHW in-frame - gcctctggattcggctttagcagctatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtagtagcgcatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtttctgcaaatggacaggctgagagtcgaggacacggccatatattactgtctgaaagatcatagagggaactactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15186 JY8QFUQ01BZBV1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGMGTVVVTNTPLYPFDI## out-of-frame + in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); cctctggattcaactttgacagcagtgccatgaactgggtccgccaggctccagggaaggggctggagtGgggtctcagccattagtggtcgtgctttcggcacagactacgcagcctctgtgaagggccggttcaccatctccagagacaattccaagaacactctgtatctgcaaatgaacagcctgcgagtcgaggactcggccatatattactgtgcgaaaggcatggggacagtggtggtcactaatactccgttgtatccttttgatatctgggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcatctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15187 JY8QFUQ01ASXGB No results +15188 JY8QFUQ01C8H70 unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 181 59.12 81/137 nt 8 7 X 8.7.X [1.17.12.X] null + No rearrangement found stop codons cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctcggtccagggcttcttcccccga +15189 JY8QFUQ01BRZIH productive (see comment) Homsap IGHV3-48*02 F (see comment) 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [2.17.38.11] FVTERGGGLLRYLDLW in-frame - Potentially, because of detected insertion/deletion Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); ggctctggattcatgttcggtagttatagtctgaattgggtccgccaggctccagggaaggGggctggagtggatttcatatattagtagcagtagtcaaacgatttactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgcgagacgacgacacggccatttactactttgtgacagagaggggcgggggcctattacgatatttggacttatggggcctgggaactcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15190 JY8QFUQ01C29TB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15191 JY8QFUQ01CFRB3 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame - ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15192 JY8QFUQ01B06FE unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFD##W out-of-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactcactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15193 JY8QFUQ01B8S75 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.37.11] CAKDGARGGGSCFNSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 177 in the user submitted sequence), (cause frameshift) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15194 JY8QFUQ01BWWAL productive (see comment) Homsap IGHV1-2*02 F 1065 100.0 214/214 nt 99.53 213/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARGPVGDSSGYEDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccggctactatatgcactgggtgcgacaggGcccctggacaagggcttgagtggatgggatggatcaaccctaacagtggtggcacaaactatgcacagaagtttcagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggagctgagcaggctgagatctgacgacacggccgtgtattactgtgcgagagggcccgtgggtgatagtagtggttatgaagactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15195 JY8QFUQ01AQSJG productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15196 JY8QFUQ01CPW4C No results +15197 JY8QFUQ01C3EAN unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 86 57.53 42/73 nt 8 X X 8.X.X [1.14.X.X] null - No rearrangement found cctctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15198 JY8QFUQ01BY87O No results +15199 JY8QFUQ01CTDOZ No results +15200 JY8QFUQ01C8066 No results +15201 JY8QFUQ01B5EW6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 690 81.04 171/211 nt Homsap IGHJ6*02 F (see comment) 188 78.69 48/61 nt Homsap IGHD3-16*01 F 3 7 8 12 7.8.12 [X.17.38.11] CAREGGRGYDMDVW in-frame + Low V-REGION identity (81,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ccctggattcaacaaatatggcatgagttgggtccgtcaggctccgggggagggtctaaagtgggtctcaactattagtgatagtactggtcgcacatactactcagactctgtgaagggccgattcaccgtctccagggaccaagccaagaactcactgtatctacaaatgaacaacctgggagtcgaggacacggctgtgtattattgtgcgagagaggggggacgtggctacgatatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +15202 JY8QFUQ01CZ173 productive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 920 90.95 201/221 nt 90.5 200/221 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 10 7 18 10.7.18 [1.17.38.11] CARSAYCGADCYSADYLQHW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'T' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtaggggttactactggaactggatccgccagttcccagggaagggcctggagtggattgggaacatctTtttacagtgggggcacctacgacaacccgtccctcaggagtcgaatttctatatcattagacacgtctaagaaccaattctccctgaagttgacctctatgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcacgcacccagccagatgggaacgtgtcatcgcctgcctggtccagggcttcttccc +15203 JY8QFUQ01A7O03 productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15204 JY8QFUQ01B57IR productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDYFDSW in-frame - tggatacaccttcaccgactacttcatacactggctgcgacaggcccctggacaacgacttgagtggatgggatggatcaaccctaagaatggtgacacaaagtatgcacagaactttcagggccgggtcaccatgaccagggacacgtccgtcagcaccatatatgtggaggtgagcagcctggaatctgacgacgcagccacttattactgtgcgagaggcttttatggtgactactttgactcctggggccagggagccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15205 JY8QFUQ01A9SL2 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +15206 JY8QFUQ01CM97F productive (see comment) Homsap IGHV3-7*01 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.16.38.11] CAISSAFFSTGHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift) ctctagattcacctttaggacatattggatgagttggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15207 JY8QFUQ01A6E51 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15208 JY8QFUQ01AGXOC productive Homsap IGHV3-66*02 F 840 88.32 189/214 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-8*01 F 3 8 7 11 8.7.11 [1.17.38.11] CASHLMVYALDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccgtcagtggcaagtacatgagctgggtccgccaggctccagggcagggactggagtgggtctcagttatctatagtactggtagtacatactacgcagattccgtgaaagggcggttcaccatctccagagacagttccaacaacactctatatcttcaaatttacggcctgagagctgacgacacggctacttactactgtgcgagtcacttaatggtgtatgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15209 JY8QFUQ01CPJ56 productive Homsap IGHV3-9*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKDRGSSSKYYFDYW in-frame - cctctggattcacctttgatgattatgtcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggggaagtgctcatatacactatgcggactctgtgaaggaccggttcaccatctccagagacaacgccatgaactccctttatttgcaaatggacagtctgagagctgacgactcggccttgtattactgtgtaaaagatcggggtagcagttccaagtattactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +15210 JY8QFUQ01DP0IL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARRTITAAGRGDDYW in-frame + cctctgaattcacctttagcagttttgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagcattggtactagtgttgttaacacatggtacgcagactcagtgaagggccggttcgccatttccagagacaattccaagagcacgctgtatttgcaaatgaatagcctgagagtcgaggacacggccgtatattactgtgcgaggaggacaataacagcagctggccgtggggatgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +15211 JY8QFUQ01BFD9Q No results +15212 JY8QFUQ01BFHGQ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 615 92.96 132/142 nt 92.25 131/142 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 7 1 10 7.1.10 [1.X.38.11] CVSDLAGQKGFW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01BFHGQ ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 38 of V-REGION: 75 nucleotides (from position 26 in the user submitted sequence), (do not cause frameshift) ctcaggattcaccttcagtagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15213 JY8QFUQ01BEMSM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15214 JY8QFUQ01DNMQD productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F (see comment) 757 83.11 182/219 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [2.17.38.11] CVRDLNWSFDSW in-frame - Low V-REGION identity (83,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cgtctgggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15215 JY8QFUQ01ASOIS productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15216 JY8QFUQ01DABC5 No results +15217 JY8QFUQ01BRBCB productive Homsap IGHV3-33*04 F (see comment) 388 78.29 101/129 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 1 X 5 14 X.5.14 [X.X.38.11] CARDAGNTWPNYFDHW in-frame + Low V-REGION identity (78,29% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttttcaattatgactccgtgaagggccgattcgccatctccagagacgattcgagggacacactgtatctccaaatgagcagcctgagagccgaggactcggccctctattattgtgcccgagatgcgggcaacacctggcccaactactttgaccactggggccagggaaccctggtcaccgtctcctcgggtgagtcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15218 JY8QFUQ01B8WMX No results +15219 JY8QFUQ01CA97H productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 89.45 195/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 15 8.8.15 [2.16.38.11] CAKNRGSAMADWYFDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'ACT' (3 nucleotides at position 84 to 86 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'G' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) gcctctggattcgactttagcggctttgccatgagctgggtccgccaggcccagggaaggggctggagtgggtctcaactattACTaatggtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttaGtttctgtgcgaaaaatagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15220 JY8QFUQ01C3A2G unproductive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARASTFYYDGSGYRD#FDIW out-of-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccactcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag +15221 JY8QFUQ01B4VQ8 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtGactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15222 JY8QFUQ01BEV2V productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 930 91.03 203/223 nt Homsap IGHJ6*02 F (see comment) 256 90.32 56/62 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [3.17.38.11] CAHGPSAAPHYYYYYGLEAW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ccaggcctctggattcacctttaccaactatggcatgaggtgggtccgccaggctccagggaaggggctggagtgggtctcagatattagcgctggtggcgataacacatactacgcagactccgtgaagggccggttcaccatctccagagacaatttcaggaacacgctgtatctgcaaatgagcagcctgagagccgaggacacggccctttattactgtgcgcatgggcccagtgcagcaccccattactactactattacggtttggaagcttggggccaagggaccaaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15223 JY8QFUQ01A4SGO productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 81 to 86 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15224 JY8QFUQ01COK28 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15225 JY8QFUQ01BME4I unproductive (see comment) Homsap IGHV4-61*02 F 956 92.76 205/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-9*01 F 1 10 7 X 10.7.X [1.17.38.11] CAREPQSKCL##YFDHW out-of-frame + stop codons tctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactca +15226 JY8QFUQ01CPB4J productive (see comment) Homsap IGHV3-13*01 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 81 of V-REGION: 'G' (1 nucleotides at position 146 to 146 in the user submitted sequence), (cause frameshift); agcctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagaGgaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15227 JY8QFUQ01BJAEF productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15228 JY8QFUQ01A6G2Q unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 943 93.9 200/213 nt 92.96 198/213 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 82 in the user submitted sequence), (do not cause frameshift) tctggattcacctttagcagccatTcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15229 JY8QFUQ01CC3ZN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15230 JY8QFUQ01A9RJ4 No results +15231 JY8QFUQ01BYAYM productive Homsap IGHV3-7*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + cctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaacctcag +15232 JY8QFUQ01B9EU8 No results +15233 JY8QFUQ01AG8ZX No results +15234 JY8QFUQ01DVIS9 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.16.38.11] CAKDQSCIVGPCGFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) ctccgaatttcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccacgggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15235 JY8QFUQ01B50LW productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15236 JY8QFUQ01B943U No results +15237 JY8QFUQ01BV21U No results +15238 JY8QFUQ01B5851 unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 106 52.86 74/140 nt 10 9 X 10.9.X [1.17.9.X] null + No rearrangement found stop codons tctccggggacagtgtctctagcagcagtgttgtttggaactggataaggcagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +15239 JY8QFUQ01CRQV8 productive Homsap IGHV3-11*04 F (see comment) 921 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARDRGCGNGACHVADYW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CRQV8 ; 8 AA in Homsap_IGHV3-11*04) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15240 JY8QFUQ01CPVTY unknown (see comment) Homsap IGHV4-61*02 F (see comment) 513 74.6 141/189 nt 10 7 X 10.7.X [2.17.26.X] null + No rearrangement found Low V-REGION identity (74,60% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctctgggtgactccattaccagtggtttttactactggaattggatcagacagcccgccgggaggggactggagtggatcggacgtgtctatattactgggagtgtcaactacagtccatccctcgaacacagagtcagtatatctctagacacgtccaagaggcaattcttcttgaggttggtctc +15241 JY8QFUQ01AZIQK unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARDCDSGECNFDYW in-frame - stop codons in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); ctgattcagcttcagtacctaGtaacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15242 JY8QFUQ01BOM0B No results +15243 JY8QFUQ01BXHXL unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt 99.55 219/220 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15244 JY8QFUQ01B0Q3Z unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15245 JY8QFUQ01CPANT unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARDRLTISALDY## out-of-frame - ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagaccccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15246 JY8QFUQ01A81TA productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'G' (1 nucleotides at position 192 to 192 in the user submitted sequence), (cause frameshift); ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaagGgccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15247 JY8QFUQ01CI7Q0 No results +15248 JY8QFUQ01BUUH0 unproductive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPPWCWG#FDNW out-of-frame + stop codons cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactccccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15249 JY8QFUQ01ATXE4 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cgtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaGgggggctggagtgggtggcaattatatggcatgatggaaccaataaatactatgcagactccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +15250 JY8QFUQ01BUYJC No results +15251 JY8QFUQ01BZ3BX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15252 JY8QFUQ01CH5S0 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); ctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtGcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15253 JY8QFUQ01BNEO3 productive Homsap IGHV3-7*01 F 1026 97.24 211/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDYGDYVAYFDYW in-frame + ctctggattcaccttcagtgcctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacgtaaagcaagttggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtttattactgtgcgagagattacggtgactacgtagcctactttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctacctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15254 JY8QFUQ01BXWUH unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 111 53.79 71/132 nt 8 7 X 8.7.X [0.17.11.X] null - No rearrangement found stop codons ctggattcaccttcagtaactatagcatgaactgggtccgccaggccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15255 JY8QFUQ01BAX70 productive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 7 8 14 7.8.14 [2.16.38.11] CARVRGYYGGQYFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) gcctctggattcaccttagtagttattggatgacctggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15256 JY8QFUQ01C27TU productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaAaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15257 JY8QFUQ01DXGAJ No results +15258 JY8QFUQ01CX04C unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 883 89.5 196/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKDRTLHTPAQMFYYGMDA## out-of-frame - Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) gcctctggatttaccttcagttcttatagtgtcaactgggtccgccaggctccagggaagggcctggagtgggtctcatatattgataatagtggttctaccatatattatgcagactctgtgaagggccgattcaccatctccagagacaatgcccagaactcactgtttctgcaaatgaacagcctgcgagccgaggacacggccgtttattactgtgcgaaagatcggacactacacacacccgctcagatgttttattatggtatggacgcctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15259 JY8QFUQ01AWR1D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [1.17.38.11] CVKDRDFLWGTYRLQLEHW in-frame + cctctggattcagatttagcagctatgccatgagctgggtccgccagactccagaaaaggggcttgaatgggtctcaggcatcaatgataacggtcgaagcataaactacgcgggctccgtgaagggccggttcaccatctccagagacaattccaagagcacgttgtatctgcagatggatagcctgagccccgaggactcgggcatatattattgtgtgaaagatcgtgatttcctttggggcacttatcgtcttcaacttgaacattggggccagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15260 JY8QFUQ01DF3V7 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcaGtctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15261 JY8QFUQ01BM98F productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15262 JY8QFUQ01A4MRV productive (see comment) Homsap IGHV3-7*01 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 7 8 11 7.8.11 [2.17.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'T' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) ggctctggattcagcttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaTggggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15263 JY8QFUQ01AISGC No results +15264 JY8QFUQ01B8XS4 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 170 58.65 78/133 nt 8 6 X 8.6.X [1.17.11.X] null - No rearrangement found cctctggattcaccttcagtagctactggatgcactgggtccgccaagcccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15265 JY8QFUQ01A1YN6 productive Homsap IGHV3-48*02 F 1026 97.24 211/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD1-1*01 F 2 8 8 20 8.8.20 [1.17.38.11] CASGERKDYEVRRDYYHGMDVW in-frame - ctctggactcaccttcagcagctatagtatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatatattagtagtactagtagtaccataaactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagtggggaaaggaaagactacgaagtacgacgggactactatcacggcatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15266 JY8QFUQ01BRHJ6 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 984 93.72 209/223 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 2 8 10 16 8.10.16 [1.17.38.11] CAADGCPGGTCYHGFDMW in-frame + ctctggattcactttcagtaacgtctggatgcactgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgctggtggggcaacagaatacgctgcgcccgtgagaggcatattctccatctcaagagatgattcaaagaacacgttgtatctgcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtgccgcagatggttgtcctggtggtacctgctatcatggttttgatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +15267 JY8QFUQ01AOXB2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 757 83.11 182/219 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARTPCSGGNCYLRGHDLW in-frame - Low V-REGION identity (83,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcgggtatttattattgtgcgcggacgccttgcagtggtggaaattgttaccttagaggccacgacctctggggccagggaacccaggtctccgtttccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15268 JY8QFUQ01CGJC3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15269 JY8QFUQ01AIAO1 No results +15270 JY8QFUQ01A1VJ5 unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CAKITPPYDRSGPLY#DYW out-of-frame + cgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattcccagaacacactgtatctgcaagtgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaataacccccccttatgacaggagtggtccattataccgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15271 JY8QFUQ01DW4KI productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt 96.89 218/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'A' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 152 to 152 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctaccaacagagctgcAttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacCccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15272 JY8QFUQ01AJQ24 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CASLNTHSGPGAERSAFDIW in-frame + ctctggatttaccttcagtctctatagaatgaactgggtccgccaggctccagggaagggactggagtgggtctcatccattactagtaccagtagttacatttattatgcagacccagtgaagggccgattcaccatctccagagacaacgccaagaactcattatatctccatatgaacagcctgagagtcgaggacacggctatatattattgtgcgagtctgaacacgcactcgggaccgggggccgaaaggtctgcttttgatatctggggccacgggacaatggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +15273 JY8QFUQ01BPEQB productive (see comment) Homsap IGHV3-7*01 F 860 88.53 193/218 nt 87.61 191/218 nt Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARRGTQLGYCASPSCPTDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'TT' (2 nucleotides at position 84 to 85 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagGctactggatgcactgggtccgccaggctccagggagggggctggagtgggtggccagcatTTaaggcagacgggaactgagaagacgtttggggactctgtgaagggccgattctccatctccagagacaacgccaggaactcagtggatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcgaggaggggaacacaactgggatactgtgctagccctagctgcccaactgacttgtggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15274 JY8QFUQ01AU6XD unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 792 85.25 185/217 nt Homsap IGHJ5*01 F 102 66.67 34/51 nt Homsap IGHD3-16*02 F 3 8 7 X 8.7.X [2.17.38.11] CAREFRAPSVGRYGMDV## out-of-frame - gcctcgggggttcagcgtcaataataacttcatgacttggttccgccaggttccagggaaggggctggagtgggtctcagttatctatacaaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccgagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtactactgtgcgagagaatttcgggcgccttctgtgggcagatatggtatggatgtctgggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15275 JY8QFUQ01CWFLX productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15276 JY8QFUQ01BZ43M productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame - ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15277 JY8QFUQ01BJQ34 No results +15278 JY8QFUQ01CR1WB productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 897 91.94 194/211 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [0.17.38.11] CTRELRLAAARDGVDIW in-frame - tgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15279 JY8QFUQ01C422J No results +15280 JY8QFUQ01COIPL productive Homsap IGHV4-61*02 F 1010 95.48 211/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*02 F 2 10 7 15 10.7.15 [1.17.38.11] CARAGKQDFWSGYSDDW in-frame + tctctggtggctccatcggcagtggtagttattactggagctggatccggcagcccgccgggaagggactggaataccttgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgctgacacggccatttattactgtgcgagagcggggaaacaggatttttggagtggttattctgacgactggggccagggaaccctggtcatagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15281 JY8QFUQ01CVCST productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARGRIVSVGMSGWFDPW in-frame - gcctctggattcacctttagcgactatggcatgagttgggtccgccaggctccagggaagggactggagtgggtctcaagtattatcgctaatggtggtgacacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15282 JY8QFUQ01B6LR9 unproductive Homsap IGHV1-8*01 F 921 92.52 198/214 nt Homsap IGHJ1*01 F (see comment) 102 65.38 34/52 nt Homsap IGHD1-7*01 F 2 8 8 X 8.8.X [0.17.38.11] CARARGVESSGIYVYHFD#S out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacaccttcaccacttatgacatcaactgggtgcgacaggccgccggacaagggcttgagtggatgggatgggtgaaccctgtcactggtaacacaggctatatacagaagttccagggcagagtcaccatgaccatgagcacctccacaagcacagcctacatggagctgagcagcctgaaatctgacgacacggccgtgtattattgtgcgagagcccggggggtagaaagttcggggatctacgtgtatcactttgactctcgggccagggaacctggtgnaccgtctcctcagcatcccgacccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +15283 JY8QFUQ01CUNY6 No results +15284 JY8QFUQ01BY866 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 962 94.42 203/215 nt 93.49 201/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAREDGSGRRHFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); ctctgggtggctccatcagGtagttactactggagctggatccggcagcccccaggaaAagggactggagtggattgggtatatcttttacactgggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15285 JY8QFUQ01BBVBY unproductive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGSHQSE#YGLDVW out-of-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcgggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15286 JY8QFUQ01B1UE8 productive Homsap IGHV4-61*02 F 893 89.59 198/221 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARDPRVICSGGSCRSSAMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaacccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagaccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15287 JY8QFUQ01AHC5C No results +15288 JY8QFUQ01DMD7I No results +15289 JY8QFUQ01C8WAN No results +15290 JY8QFUQ01AFU1T unproductive Homsap IGHV3-7*01 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [2.17.38.11] CARWRGQQSEMEY## out-of-frame - gcctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15291 JY8QFUQ01C94YX unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 765 83.41 181/217 nt 82.49 179/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.37.X] null + Rearranged sequence but no junction found Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT at codon 74 of V-REGION: 'T' (1 nucleotides at position 128 to 128 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 191 in the user submitted sequence), (cause frameshift) cctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtggggggTccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagcccgaggacacggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15292 JY8QFUQ01BZSGP productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt 91.24 198/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'G' (1 nucleotides at position 193 to 193 in the user submitted sequence), (cause frameshift); ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatGggggatcatctatcctggtacctctgagaCccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaagGgccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15293 JY8QFUQ01AOAL3 productive (see comment) Homsap IGHV3-9*01 F (see comment) 779 84.4 184/218 nt 83.94 183/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaGggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15294 JY8QFUQ01A93ME unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 844 86.94 193/222 nt 86.49 192/222 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-18*01 F 3 8 10 X 8.10.X [1.16.38.11] CTWGQHWLFSAY#W out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggactcactttcagtgacgcctggatgacctgggtccgccaggttccagggaagggctggagtgggttgcccatattagatggaactctgatgactggaccacagactacgctactcccgtgaagggcagattcaccatctcaaaagatatttcagagaacacgctgtatctacaaatgaacagcctgataagcgaggatacaggcgtttattactgtacctggggacagcactggttattttcggcttacctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15295 JY8QFUQ01CTGXO productive (see comment) Homsap IGHV3-7*01 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'A' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); agcctctacattcacgtttagtcggtattggatgagctgggtAccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15296 JY8QFUQ01AA0G1 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15297 JY8QFUQ01CZZJY unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 881 90.23 194/215 nt Homsap IGHJ4*03 F (see comment) 78 62.5 30/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [0.17.38.11] CANGGVVT#DLDYW out-of-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) caggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaacgggggggtggtaacggcgaccttgactactgggggccagggaagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15298 JY8QFUQ01C00M2 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggccctatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15299 JY8QFUQ01BDZ68 No results +15300 JY8QFUQ01CROXD No results +15301 JY8QFUQ01BYT5N productive Homsap IGHV3-7*02 F 866 90.09 191/212 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [X.17.38.11] CARDQVTEDYW in-frame - ggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15302 JY8QFUQ01CIAOZ No results +15303 JY8QFUQ01BU5OB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15304 JY8QFUQ01CIG7L productive Homsap IGHV3-48*01 F 860 88.53 193/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + tctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15305 JY8QFUQ01C9708 unproductive Homsap IGHV3-11*01 F 942 92.27 203/220 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [2.17.38.11] CVRYWGSYYYYNGLDV## out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) gcctctgggattcaccttcactgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcacacattagtagtggtggtagaaccattgcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtttctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgagatattggggcagctactattactataacggtctggacgtctggggggcaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15306 JY8QFUQ01BN8PD unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - stop codons cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgagtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15307 JY8QFUQ01DGL72 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15308 JY8QFUQ01DM60H productive (see comment) Homsap IGHV3-48*02 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAKDRGGSAYPIFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtgggAtttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15309 JY8QFUQ01BBH3B productive (see comment) Homsap IGHV3-74*03 F (see comment) 682 78.83 175/222 nt 78.38 174/222 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [3.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (78,83% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 128 to 128 in the user submitted sequence), (cause frameshift); gcctctggaattcacgtttccacacctcctggatggcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaAagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15310 JY8QFUQ01BU6HU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15311 JY8QFUQ01CIVAZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [1.17.38.11] CTKTRVVLGITFPFYIYGLDVW in-frame + Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacgttcgacaactatgccatgagctgggtccgccaggcaccaggaaaggggctggagtgggtctccagtattagtggtaatggagaaattgtacaccacgcagacgccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtttttgcaaatgaatggagtgagagacgacgacacggccatttactactgtacgaaaacacgcgttgtgttgggaattacatttccgttctatatctatggtctggacgtctggggccaagggaccacggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +15312 JY8QFUQ01DBTJ6 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-23*01 ORF 2 8 8 10 8.8.10 [1.17.38.11] CVKDLLGGDPFW in-frame - cctctggattcaccttcagtcgctatggcttgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcagatgatgggaagaataaattctatacagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgatgtttgtgcaactgaacagtctgagagctgaggacacggctgtgtattactgtgtgaaagacctactaggtggtgaccccttttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15313 JY8QFUQ01BLHAL productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 980 95.35 205/215 nt 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagtcattacCtggagctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +15314 JY8QFUQ01AWFBK unproductive Homsap IGHV3-9*01 F 918 91.71 199/217 nt Homsap IGHJ6*01 F (see comment) 108 63.49 40/63 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDGSAIPVTGTYFEY# out-of-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtgacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagcccggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +15315 JY8QFUQ01CII5W productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 773 84.65 182/215 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARERGSGPPTGMDVW in-frame + Low V-REGION identity (84,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) gttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaagaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15316 JY8QFUQ01CQ28T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtagtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15317 JY8QFUQ01BXV0U productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15318 JY8QFUQ01DRZIH productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.18 194/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccaCtttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15319 JY8QFUQ01DWRUR unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 863 87.05 195/224 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 10 X 8.10.X [1.17.38.11] CTADVPVTISAK#DFW out-of-frame + cctctggattcactttcaatggcgcctggatgaactgggtccgccaggctccagagaagggtctggagtgggttgcccgtataaaaacttttggtgaaggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcaaaaaaagggctgtatctgcagatggacagcctgagaatcgaggacacagccaagtattactgcaccgcagatgtcccagtcaccattagcgcaaaattgacttctggggccagggaaccctggtcaccgtctcctcagnatccccggaccagccccaaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15320 JY8QFUQ01ATZED productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame + tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15321 JY8QFUQ01B1EK1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1043 98.6 212/215 nt 97.67 210/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*03 F 3 8 8 18 8.8.18 [1.16.37.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 90 of V-REGION: 1 nucleotides (from position 174 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15322 JY8QFUQ01CWOBR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKDGGDTYGYARYW in-frame + ctctggattcaagtttgatgattccggcatgagctgggtccgccaagctccagggaaggggctggagtgggtctcaacaatttttgccagtggtgttaccacatattacgcagactccgtgaagggccgattcaccatctccagagacaattccaataatagagtgtttctgcaaatgaccagcctgagagacgaagacacggccgtatactactgtgcgaaagatggtggagacacatatggttacgctcgctactggggccagggaagtctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatcctggtccagggcttcttccccca +15323 JY8QFUQ01AX6F4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15324 JY8QFUQ01C0DZ4 productive (see comment) Homsap IGHV4-4*07 F 849 88.79 190/214 nt 87.85 188/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 7 11 8.7.11 [1.17.37.11] CARSGWDNQFDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'TGGCAC' (6 nucleotides at position 23 to 28 in the user submitted sequence), (do not cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) tctctggtgtcgccaccagtagTGGCACttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaaccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15325 JY8QFUQ01CYI7D productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15326 JY8QFUQ01DP020 No results +15327 JY8QFUQ01AS8FY productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSGSSEYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'T' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tctgggattcagcttaagttcttatggcatgaactgggtccgccaggctccaTgggggggggctggagtgggtctcattcattaacagtattagtagttataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15328 JY8QFUQ01B3M9E No results +15329 JY8QFUQ01ADQQX unknown (see comment) Homsap IGHV3-48*03 F 873 89.4 194/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found ctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15330 JY8QFUQ01AW02O productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 828 87.1 189/217 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD3-16*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASLNTHAGPGAERSAFDVW in-frame + ctctggattcatcttcagtaactatagaatgaactgggtccgtcaggctccagggaaggggctcgagtgggtctcgtccatcaccagttccagtagttacatctactatgcagactcggtgacgggccgattcaccatctccagagacaactccaaggggtcactctatctgcacatgaacgaccttagggccgaagacacggctgtctattactgtgcgagcctaaacacgcacgcgggaccgggagccgagaggtctgcttttgatgtctggggccgagggacaagggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggccttc +15331 JY8QFUQ01ARANR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + tctctggattcaccttcaggaactattggatgcactgggtccgccaagctccagggaaggggctggagtgggtctcacgtatcaatggcgacggaagtagcacaagctacgcggactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15332 JY8QFUQ01B3GAT No results +15333 JY8QFUQ01AJYIB productive Homsap IGHV3-7*01 F 912 92.06 197/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [0.17.38.11] CVRGRDGVNFGEMDYW in-frame - tgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15334 JY8QFUQ01BH4WY No results +15335 JY8QFUQ01BNTRC No results +15336 JY8QFUQ01ATI4C productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1058 98.17 214/218 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +15337 JY8QFUQ01A5XL0 productive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15338 JY8QFUQ01AWR2C productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15339 JY8QFUQ01CBZAC productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 856 88.13 193/219 nt 86.76 190/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [2.17.38.11] CTRVGTFNWFGPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); gcctctggattcaactttgcagattatggcttggGgctgggtccgccaacttccagggGAagggggctggaatgggtcggtggtgttaattggaatgGggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +15340 JY8QFUQ01ALW0Z productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASDLGGQKSYW in-frame + ctctggattcacctttagtgactattggatgagctgggtccgccaggctccagggaaggggctagagtgggtggccaacataaatagagatggaagtgagcaacactatgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +15341 JY8QFUQ01BL77H productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [1.17.38.11] CTRELRVAAARDGVDIW in-frame + ctctggattcaccgtcagtaccaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagtaatttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgatggtcgtgcgcatgcctggctccagggcttcttccccca +15342 JY8QFUQ01DJJA2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15343 JY8QFUQ01AJXYH unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 120 57.14 60/105 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons cctctggattcaccttcagtcgttatagcatgaactgagcctctgcagcacccagccagatgggagcgtggtcatcgcctgcctggtccagggcttcttccccca +15344 JY8QFUQ01COOK2 No results +15345 JY8QFUQ01BRJW5 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 289 65.16 101/155 nt 8 8 X 8.8.X [1.17.17.X] null - No rearrangement found Low V-REGION identity (65,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatatgaacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +15346 JY8QFUQ01CCKLV productive (see comment) Homsap IGHV3-7*01 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-2*01 F 3 8 7 19 8.7.19 [1.17.38.11] CVRDGGVIVVVPMDYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 2 nucleotides (from position 83 in the user submitted sequence), (cause frameshift) ctctggtttcacatttagtacgtactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacatagcgagatggaactgagagtcattatgtggactctgtgaagggccgattcatcatctccagagacaactccaggaatttactgtatctccaaatgaacagcctgagagtcgaagacacggctgtgtattattgtgtgagagatgggggtgttattgtagtagtgccaatggactattacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15347 JY8QFUQ01A1409 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.37.11] CVSDLAGQKGF# out-of-frame + in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15348 JY8QFUQ01CYVB4 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F 814 86.57 187/216 nt 86.11 186/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARPHHNSGYSFDHW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) gtctgatttcaacgtcggtgactttgacatgcactgggtccgccagactccagacaaggggctggagtgggtggcactttttggtatgacggaaagaggaaatattatgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacaccctgtatctgcaaatggacagcctgagagccgacgacacggctacctacttttgtgcgaggcctcatcataatagtggttattcctttgaccactggggccagggaacccaggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15349 JY8QFUQ01A8IF7 No results +15350 JY8QFUQ01DQDY7 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 95.85 208/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD7-27*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGANWGPGP#FDYW out-of-frame + ctctggattcactttcagtagaaactggatgaactgggtccgccaagctccagggaaggggctggtntgggtctcacgtattagtagtgatgggagtagcacaacctacgcggactccgtgaagggccgattcaccatctacagagacaacgccaagaacacgctgtatgtgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaggggccaactggggaccgggcccccttttgactactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15351 JY8QFUQ01C6QNV unproductive (see comment) Homsap IGHV3-7*03 F 910 90.87 199/219 nt 90.41 198/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [2.17.38.11] CANWLSGTHSKFDYW in-frame - stop codons in CDR1-IMGT at codon 36 of V-REGION: 'AC' (2 nucleotides at position 23 to 24 in the user submitted sequence), (cause frameshift); gcctctggatttagcatttagaACccttttggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15352 JY8QFUQ01BF71M No results +15353 JY8QFUQ01DWIC5 unproductive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 591 95.38 124/130 nt 94.62 123/130 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-25*01 F 1 8 X X 8.X.X [1.3.31.11] CAKGGW*R##LDYW out-of-frame + stop codons in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 38 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagtaaccattggatgaactggggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggatggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +15354 JY8QFUQ01CI6DV unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +15355 JY8QFUQ01A3MV4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15356 JY8QFUQ01BX5EZ unproductive Homsap IGHV3-11*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F (see comment) 96 66.67 32/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CADIRLGDWCFDI# out-of-frame - Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) cctctggattcaccttcagtgaccactacatgagttggatccgccaggctccagggaaggggctggagtggatttcatatattagtactagtggtaatatgatttattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaactcactgtatctgcagatgaacagcctgagagccgaggacacggccgtctatttctgtgccgatataagactgggtgactggtgcttcgatatctgggccggggcaccctggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15357 JY8QFUQ01BW9DT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15358 JY8QFUQ01DQMRU unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 957 94.39 202/214 nt 93.46 200/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 48 of V-REGION: 'AA' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccggggaaAAagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +15359 JY8QFUQ01ACSEL productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15360 JY8QFUQ01B0KVC unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 927 92.17 200/217 nt Homsap IGHJ4*03 F 132 75.0 36/48 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CARVGGTEEFAGMLELDY## out-of-frame + gtctggattcagtttcagtagctttggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatgatctggtatgatggaactaataaatattatgcagactccgtgaagggccgattcaccatctcgagagacaattccaagaacacactgtttctgctcatggacagcctgacagccgacgacacggctgtctattactgtgcgagagtcgggggaaccgaggagttcgctggtatgttggaacttgactactgggggccaggggaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +15361 JY8QFUQ01CCIFV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'G' (1 nucleotides at position 189 to 189 in the user submitted sequence), (cause frameshift); ctctacattcgcctttagcaactatgccatgaGgctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgGagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15362 JY8QFUQ01BAS63 No results +15363 JY8QFUQ01AOUQ1 unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt 92.13 199/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD3-22*01 F 3 7 8 X 7.8.X [1.17.38.11] CARHSHSSGYSSLDALEI## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 93 of V-REGION: 'C' (1 nucleotides at position 182 to 182 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) ttctgcatatagttttccagttactggatcgcctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatcaatcccggtgactctgataccagatatagcccgtcctttcaaggccaggtcaccgtctcagccgacaggtccatcagtaccgcctacctgcagtggaaaaCgcctgagggcctcggacaccgccatgtattactgtgcgcgacactcccacagtagtggttattccagccttgacgctcttgagatctggggcccaagggacaatggtcaccgtctcttctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15364 JY8QFUQ01AK1U1 unknown (see comment) Homsap IGHV1-2*01 F 164 55.42 92/166 nt 7 8 X 7.8.X [X.17.23.X] null - No rearrangement found atacaccttcagcaactactatagacactgggtgcgacaggcccctggacaagggcttgagtggatgggaatgatcagccccaaggtcttcccgcctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15365 JY8QFUQ01ATAHA unknown (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagGggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaaatgggactactggggggacagggggaacccctggtcaccgtctccctcagcctccaccaaggggccccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15366 JY8QFUQ01AVMUI No results +15367 JY8QFUQ01B2NEX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +15368 JY8QFUQ01B6LQX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGLGSYLYCFDYW in-frame + ctctggattcccctttatcagctatgccatgacctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtggtgatgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggtttggggagttatctctactgctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtctagggcttcttccccca +15369 JY8QFUQ01BHYPA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYFYYFDYW in-frame + cctctggattcacctttagccactatgccgtgacctgggtccgccaggctccagggaagggtctggagtgggtctcaactattagtggtagtgatggtagcacgtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagaagtatcactatggttcggggacttacttctactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggttcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +15370 JY8QFUQ01AG87O productive (see comment) Homsap IGHV4-61*02 F 902 90.05 199/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); tctctggtggccCccatcagcagtggtacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccacctacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgccgctgacacggccgtatattactgtgcgagagaacatagtaggacgatgggcggggcgagagagcttgactcctggggcctgggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc +15371 JY8QFUQ01AU60E productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt 93.78 211/225 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGNYYDSGGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctagcagcagtgttgTtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcgaataactatcaagccagacgcatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtatattactgtgcaagagggggtaattactatgatagtggtggtcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +15372 JY8QFUQ01APAT3 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 87 90.48 19/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattaaccctcagtga +15373 JY8QFUQ01DVDDQ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CAKDLVVTSIGPQGIHGH## out-of-frame + ctctgggttcacctttagcagctatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaagtatcagttttagtggtgagagaacatattatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacagtacatttgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaagatctggtggtgactagtattggcccccagggaatccatggccactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +15374 JY8QFUQ01CQ6E4 productive Homsap IGHV3-9*01 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CVKDRKGSNWYYFENW in-frame - cagcctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15375 JY8QFUQ01BKTS0 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 996 95.0 209/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 3 9 9 19 9.9.19 [X.17.38.11] CARSSRRDRLSDRNYYELDFW in-frame - ggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccctcaccccagacacatccaagaaccagttctccctgcaattgaactccgttagtcccgaggacacggctgtgtattattgtgcaagatcttccagacgcgatcgtttgtctgataggaactactatgagctggacttctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15376 JY8QFUQ01BNC1N unknown (see comment) Homsap IGHV1-8*01 F 580 92.54 124/134 nt 8 8 X 8.8.X [0.17.11.X] null - No rearrangement found tggagacaccttcaccagttatgatatccactgggtgcgacaggcctctggacaagggcttgagtggatgggatggatgaaccctaacagtggtaacacaggctattcacagaggttccagggcttcttcccca +15377 JY8QFUQ01A4Y3T No results +15378 JY8QFUQ01C0W1R unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 835 88.26 188/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-19*01 F 3 7 7 X 7.7.X [0.17.38.11] CAKVYTGAWGIL#FDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 92 in the user submitted sequence), (cause frameshift) ctggattcagcttagcaactttgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtactttagcacccattatgccgactccgtgaagggccgcttcaccatctccagagacaatttcaggagcaccttatatctgcagatgaacaacctgagagccgacgacacggccatatattactgtgcgaaagtgtacaccggtgcctgggggatcctaattttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15379 JY8QFUQ01ALUAS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15380 JY8QFUQ01BYTWC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 780 84.09 185/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKDTITMGGDVAPLFDYW in-frame - Low V-REGION identity (84,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release acctctgggattcacctttagtaactatgacatgggctgggtccgccaggctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15381 JY8QFUQ01AKVV1 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATLPSPGARRPFDHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ttctggatacagttttgccgactattggatcggctgggtgcgccagaggcccgggaAaaggcctggagtgcatgggggtcatctatcctggtgactctgatgtcagatacagcccgtccttccggggccaggtcaccatctcagccgacaagtccatcagcactgcctacctgcagtggagcagcctgaaggcctcggacaccgccttgtatttttgtgcgacccttccctcgcccggggcccgaagaccctttgaccactggggccagggaacccgagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +15382 JY8QFUQ01B4YS0 productive Homsap IGHV3-48*01 F 1085 100.0 218/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15383 JY8QFUQ01CJO9P No results +15384 JY8QFUQ01B56KK productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15385 JY8QFUQ01AMI2A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + cctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctggcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15386 JY8QFUQ01ANXW0 No results +15387 JY8QFUQ01A8XOR productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGVFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttggggtttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15388 JY8QFUQ01BU5BA productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F (see comment) 669 79.44 170/214 nt 78.04 167/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-10*01 F 2 8 8 21 8.8.21 [0.17.38.11] CARERRPGGYPNGYHHFYGMDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'G' (1 nucleotides at position 136 to 136 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 210 to 210 in the user submitted sequence), (cause frameshift); ctctgatacaattagtcgttatggcatgcactgggtccgccaggctccaggcaaggggctggagtggctggcaattatttcatatgatggaaataggGatatatgttggagactccgtgaagggccgcttcaccgGtttccagagacaacgccgggaggactctgtttctgcaaatgaacagtctgagaggtgatgacaccgccacataCtttttgtgcgagagagcggcgtccgggtggctatccaaatggctaccaccatttttacggcatggacgtctggggccaagggaccagggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15389 JY8QFUQ01AO1TQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.99 194/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagacttcgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15390 JY8QFUQ01C7O3L No results +15391 JY8QFUQ01BTK8S unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 93.72 209/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 X 8.10.X [1.17.38.11] CTTGGWN*L##W out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 200 to 200 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaaGtatgctgtatctgcaattgaacagcctgaaaacCcgaggacacagccgtgtatttctgtaccacagggggttggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccccttggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15392 JY8QFUQ01CV1TO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 978 94.09 207/220 nt 93.64 206/220 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD4-11*01 ORF 3 8 8 X 8.8.X [2.17.38.11] CAKQTIFDYYYYGLDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); agcctctggattcacctttatcaactatgGgcatgagctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15393 JY8QFUQ01AYCCC productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 894 91.12 195/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-18*01 F 1 8 8 15 8.8.15 [0.17.38.11] CAIVDTNLVSATGKDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacaccttcagcaactactatagacactgggtgcgacaggcccctggacaagggcttgagtggatgggaatgatcaaccctagtagtgattacaaatattacgcacagaaatttcagggcagagtcaccatgaccagggacacgtccacgagcacagtcttcatggagctgagtagcctgagatctgacgacacggccgtgtattattgtgcaatagtggacacaaatttggtttcggcgaccggtaaagactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15394 JY8QFUQ01B8PFU productive (see comment) Homsap IGHV4-31*06 F (see comment) 740 81.82 180/220 nt 81.36 179/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARVWVAGSRDENFDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); tctcgggtggttccatgacgagtactaAttttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgacctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15395 JY8QFUQ01BNK9R No results +15396 JY8QFUQ01BJ5NY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagtacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15397 JY8QFUQ01A3ZKS productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15398 JY8QFUQ01DDXP7 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.12 203/218 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGAQLLCQ*WA*LL# out-of-frame - stop codons cctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggantgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagaggggcacagttattatgtcagtagtgggcctgactactgggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15399 JY8QFUQ01ATTGD unproductive Homsap IGHV3-9*01 F 1026 97.24 211/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD1-7*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDMGYTWKYIDH## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattacttggaacagtggtaggataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattattgtgcaaaagatatggggtatacctggaagtacattgaccactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15400 JY8QFUQ01AYNMV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15401 JY8QFUQ01AP0IP productive Homsap IGHV3-7*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15402 JY8QFUQ01DV9LQ productive (see comment) Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 98.61 213/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctatagcatgaactgggtccGgccaggctccagggaagggctggagtgggtttcatGacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15403 JY8QFUQ01CHTJ1 unproductive Homsap IGHV4-61*02 F 992 94.57 209/221 nt 94.12 208/221 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-10*01 F 3 10 7 X 10.7.X [1.17.38.11] CARGSGSGSYSNL## out-of-frame - in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagGcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggccccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacggcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15404 JY8QFUQ01CQ2B9 unproductive (see comment) Homsap IGHV3-30*01 F 869 88.99 194/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARVGGNRGVRWYVG##DYW out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagtcggggggaaccgaggagttcgctggtatgttggaacttgactactggggccaggggaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15405 JY8QFUQ01DMHZC productive Homsap IGHV3-48*01 F 1005 95.45 210/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - agcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15406 JY8QFUQ01A8JNE productive Homsap IGHV2-5*02 F 1022 91.02 223/245 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 18 10.7.18 [9.17.38.11] CAHNSLYDRNGYYLTYFDHW in-frame + agaccctcacactgacctgcaacctctctggggtctcactcagcagtcgtggagtgggtgtgggctggatccgtcaggccccaggaaaggccctggagtggcttgccctcattgattgggatgatgacaagcgctatagtccatctctaaaggggaggctcaccatcaccagggacacctccacaggccaggtggtcttcacaatgaccaacatgcaccctgtggacacagccacatattactgtgcacacaacagtctctatgataggaatggctattatttgacgtactttgatcactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +15407 JY8QFUQ01CJVYW productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1085 100.0 218/218 nt 99.08 216/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [2.16.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccGtttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15408 JY8QFUQ01BFP4R unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 845 88.37 190/215 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [0.17.38.11] CASFRVLESGY## out-of-frame - ctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactgggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15409 JY8QFUQ01ANW4L No results +15410 JY8QFUQ01BM8SJ unknown (see comment) Homsap IGHV3-69-1*02 P 1029 98.13 210/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + Rearranged sequence but no junction found however the closest V is a pseudogene The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctagattcaccttcagtgagtactacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattaggagtagtagtaccatatactacgcagactctatgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtttattactgtgcgagagacgcaatgaattcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15411 JY8QFUQ01BO7ET No results +15412 JY8QFUQ01BXGYG unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtatcttcggactcgtctgggcccgtggcaccctggtcactgctctcctcagcctccaccaaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15413 JY8QFUQ01CPBJI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYYYHFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); cctctggattcaccGtttagcaactatgccatgagctgggtccgccaggctccagggaAaggggctggagtgggtcgcaactattatttatagtggcgatagtacatactacgcagattccgtgaggggccggttcaccatctccagagacaattccaagaacactctgcatctgcatatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaaagtatcactatggttcggggacttattattaccacttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15414 JY8QFUQ01BCUID productive Homsap IGHV3-48*04 F 1005 95.45 210/220 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CARDAGGSGWYLYYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) agcctctggattcaccttcagtagttataccatgcactgggtccgccaggctccagggaaggggctggaatgggtctcatccattagtagtagtagtactaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacggcctgagagccgaggacacggctgtttattcctgtgcgagagatgcggggggcagtggctggtacctttactactttgactcctggggccagggaaccctggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15415 JY8QFUQ01AE4IG productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame - tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15416 JY8QFUQ01ALUYN No results +15417 JY8QFUQ01APVC5 productive Homsap IGHV3-48*03 F, or Homsap IGHV3-48*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-74*03 F (see comment) 393 78.46 102/130 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 X 5 17 X.5.17 [X.X.38.11] CVRDSGPSGYARYESMDVW in-frame - Low V-REGION identity (78,46% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcagcctcacttcctatggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagtggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15418 JY8QFUQ01BP3RA productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 953 93.95 202/215 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-2*01 F 2 8 7 12 8.7.12 [1.17.38.11] CAVSTTTWGWFDPW in-frame - tctatggtgggtccttcagtggttactactggagctggatccgccagcccccaggggaggggctgcagtggattggaagagtcaatcatagtggaagcaccagctacaacccgtccctcaagagtcgagtcaccatgtcactagacacgtccaagacccacttttccctgaagctgacctctgtgaccgccgcggacacggctgtgtattactgtgcggtgtctactaccacctgggggtggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15419 JY8QFUQ01DA8PQ No results +15420 JY8QFUQ01BQ849 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15421 JY8QFUQ01B791I productive Homsap IGHV1-3*01 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARGRYDSSGRGHEYW in-frame - ctggatacaccttcaccagtttcagtatccattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacggtggcaatggtaacacaaaatattcacagaagttccaggacagactcaccattactagagacacatccgcgagcacagcctacatggacctgagcagcctgagatctgaagacacggctgtctattactgtgcgagagggcgctatgatagtagtggtcgtggccatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15422 JY8QFUQ01AS13H unknown (see comment) Homsap IGHV3-48*02 F (see comment) 356 62.84 137/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (62,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15423 JY8QFUQ01ALDY2 productive Homsap IGHV4-59*03 F 899 91.16 196/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-23*01 ORF 3 8 7 9 8.7.9 [1.17.38.11] CARGVTPEGYW in-frame + tctcgggtgactccatcactcctaactcctggagctggatccggcagcccccagggaagggactggagtggattggttatatctattacagtggaatcaccaagcacaacccctccctcaagagtcgagtcgccatttcagtagacacgtccaagaaccaattttccctgaggctgagttctgtgaccgctgcggacacggccgtttatttctgtgcgaggggggtcactccggagggctactggggccagggaatcttagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +15424 JY8QFUQ01BJHAO productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaAaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +15425 JY8QFUQ01CE696 productive Homsap IGHV3-11*01 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD1-26*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARDGDDYRSYYYGMDVW in-frame + cctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcatggtatacctggcagactctgtgaagggccgattcatcatctccagggacaacggcgagaactcactgtatcttcaaatgaacagcctgagagccgaagacacggccgtgtattactgtgcgagagatggggacgactacaggtcgtactactatggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc +15426 JY8QFUQ01B8GRW productive Homsap IGHV3-7*03 F 855 88.48 192/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame - ctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15427 JY8QFUQ01A2DRJ No results +15428 JY8QFUQ01AUB3V productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +15429 JY8QFUQ01C2ZU3 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 817 85.59 190/222 nt 84.68 188/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [2.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); gtctctggtgactccatcagtagtGactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15430 JY8QFUQ01ARLF9 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 906 90.45 199/220 nt 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) ggcctcctggattcaccCtttggttattatggcatgactgggtccgccaagctccggggaagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15431 JY8QFUQ01BOD1U productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 996 95.0 209/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [2.17.38.11] CVSSPYFYDSNGYW in-frame - ggcctctggattcatcttcagtaaatataccatgaaatgggtccgccaggctccagggaaggggctggagtgggtctcatccatcagtagtagtagtggttacatatactactcagattcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15432 JY8QFUQ01C7COD productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaAaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15433 JY8QFUQ01A727M No results +15434 JY8QFUQ01CPKFW productive Homsap IGHV3-72*01 F 884 89.14 197/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 3 8 10 9 8.10.9 [0.17.38.11] CAVAAPPYDGW in-frame - ctggattcaccttaagtgacttctacatggactggctccgccaggctccagggaaggggctggagtgggttggtcgcagtagaaacaaagctaatggttacagtacacaattcgccgcatctgtgatgggcagattcaccatctcaagagatgactcaaagaatttactatatctacaaatgagcagcctgaaaaccgaggacacggccatttattactgtgctgtcgcagcccccccttatgacggctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15435 JY8QFUQ01AJL5M productive Homsap IGHV3-48*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15436 JY8QFUQ01AK6RN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15437 JY8QFUQ01CFF9I unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 966 94.86 203/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 X 8.7.X [1.17.38.11] CASANYDYALGGVIV#DYW out-of-frame - tctgggtggctccatcagtagttactactggagctggatccggcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaacacaagcccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgctttggggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15438 JY8QFUQ01CQEAZ productive Homsap IGHV4-59*02 F 962 94.42 203/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 3 8 7 17 8.7.17 [1.17.38.11] CARHSMGVTIVRGHWFDPW in-frame + tctctggtggctccgtcagcagttattactggagctggatccgacagcccccagggaagggactggagtggattggctatatccatgacagtgggagcagcaactacaacccctccctcaagagtcgagtcaccatatctgtggacacgtccaagaaccagttctccctgaagctgacttctgtgaccgctgcggacacggccgtatattactgtgcgagacattctatgggtgttactatagttcggggacactggttcgacccctggggccagggaaccctggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtggaactc +15439 JY8QFUQ01CX9AH productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 849 88.32 189/214 nt 86.45 185/214 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 7 12 8.7.12 [1.17.38.11] CARQRYYESDGQTW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'CGGAAG' (6 nucleotides at position 19 to 24 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 31 of V-REGION: 6 nucleotides (from position 17 in the user submitted sequence), (do not cause frameshift) ctctggtggctccatcacCGGAAGtagttattattggggctggattcgccagTcccccagggaaggggctggagtggattggaagtatgtattacactgggagcaccgactacaaccccGtccctcaagagtcgggtcacgatatccgcagacaagtcgaagagccaggtctacctgaagttggactctgtgaccgccgcagacacaggtgtttattactgcgcgagacaaaggtactatgaaagtgatggccaaacctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15440 JY8QFUQ01AFMHP unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 918 91.71 199/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-8*02 F 2 9 7 X 9.7.X [1.17.38.11] CARLTDWWG##FDHW out-of-frame + stop codons in CDR1-IMGT at codon 36 of V-REGION: 'CTT' (3 nucleotides at position 24 to 26 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 34 of V-REGION: 3 nucleotides (from position 20 in the user submitted sequence), (do not cause frameshift) ctctggtggctccatcagcggtaCTTctcattactggggctgggtccgccagcccccagggaaggggctggagtggattggcagtatctactctggtgggaccacctactacaaccCcgtccctcaagagtcgactcaccatgtccgtcgacacgtccaagaaccagatgtccctgcggctgagctctgtgaccgccgcagacacggctgtctattactgtgcgagactgacagactggtggggggcactttgatcactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctggcctggtccagggcttcttcccc +15441 JY8QFUQ01CZKRB productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 971 94.88 204/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD5-24*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CARWAYGYNYWDLW in-frame + tctctggtggctccatcagtgattactactggacctgggtccggcagcccccagggaagggactggagtggattggatatgtcgaatacagtgggaacaccaactacaacccctccctcaggagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagatgggcctatggctacaattattgggatctctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15442 JY8QFUQ01BITUS productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 845 86.61 194/224 nt 85.27 191/224 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 1 8 10 14 8.10.14 [1.17.38.11] CSRARWSTTWYVFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'GC' (2 nucleotides at position 161 to 162 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 98 of V-REGION: 'G' (1 nucleotides at position 209 to 209 in the user submitted sequence), (cause frameshift); cttctggattcatgtttggtgatcatgggatgggctggttccgccaggctgcagggaagggcctggagtgggtaggcttcattGaaaactacaccttatggtgcggcaagccattacgccgcgtctgtgggaggcagattcagcatctcaagagatgattGCcaaaaagcgtcgcctatttgcaaatgagcagtctggaaaccgaggaGcacagccgtgtattattgttctcgagcgcggtggagcaccacttggtacgtctttgactactgggcccagggaacccaggtcgccgtctcctcagcctcccaccgaacgggcccatcggtccttgccccctggccaccctcctccaagagcacctgctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15443 JY8QFUQ01ALTNT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15444 JY8QFUQ01CEVLG unproductive Homsap IGHV3-72*01 F 1083 98.65 220/223 nt Homsap IGHJ6*04 F (see comment) 108 66.67 36/54 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYDP## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15445 JY8QFUQ01DPKH6 productive Homsap IGHV3-48*01 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaagggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaaggggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15446 JY8QFUQ01AZQKC productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [2.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); agtctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15447 JY8QFUQ01BMLGO productive Homsap IGHV3-23*05 F 815 86.24 188/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKSTGHSGWYPFDNW in-frame + cctctggattcacattcagcaattatgccatgggctgggtccgccaggctccagggaaggggctggagtgggtcgctgctattgatggcagtggtgaaagaactcactatgcagactccgaacagggccgcgtcaacatctctagagacaattccaagaacatgatatatgtgcaattgagcagcctgagagccgaggacacggccatgtattactgtgtgaagtccaccgggcacagtggctggtatccctttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15448 JY8QFUQ01B8C5C No results +15449 JY8QFUQ01AKXHF unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 123 68.42 39/57 nt 8 X X 8.X.X [1.9.X.X] null + No rearrangement found ctccggattcacctttagtagttactggatgcactgggtccagggcttcttccccca +15450 JY8QFUQ01AQF2V No results +15451 JY8QFUQ01AQZ7P productive Homsap IGHV3-66*02 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame + ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15452 JY8QFUQ01DH3CZ productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDAFEMW in-frame + ctctggattcatctttgatgattttggcatgaattgggtccgccaagctccagggaaggggctggagtgggtcgctggtatcagttggaatggtggcaaagcaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcaatgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15453 JY8QFUQ01CMRID unproductive (see comment) Homsap IGHV3-48*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CARVEKLL**WWF#FDYW out-of-frame + stop codons ctctggattcaccttcagtagctatagcatgaattgggtccgccaggctccagggaagggactggagtgggtttcatacattagtggaagtagtaataccatgtactacgcagactctgtgaagggccgattcaccatctccagagacaatgcccagaattcactacatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagtggaaaagttactctgatagtggtggttcgtttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +15454 JY8QFUQ01B2HM8 productive Homsap IGHV3-33*04 F (see comment) 698 80.28 175/218 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame - Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release catttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15455 JY8QFUQ01BITPA unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 769 83.8 181/216 nt Homsap IGHJ2*01 F (see comment) 32 63.16 12/19 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttcccgaaccggtgacggtgtcgtggaactcag +15456 JY8QFUQ01DPAMQ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [0.17.38.11] CTRDIGGRYSYW in-frame - tggttacacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15457 JY8QFUQ01BC6IA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15458 JY8QFUQ01BQUG5 productive Homsap IGHV3-13*01 F 985 95.37 206/216 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPL in-frame + gcctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcaaatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgaccccctgggccagggaacctgtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15459 JY8QFUQ01C1155 productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F (see comment) 609 75.45 166/220 nt 75.0 165/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-13*01 F 3 8 8 15 8.8.15 [2.17.37.11] CARGQKWLQVARWFDPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (75,45% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 87 of V-REGION: 1 nucleotides (from position 170 in the user submitted sequence), (cause frameshift) aggtagtggatacgaaattcgacgactatagtatgcactgggtccgcctagtcccagggacgggtctgcagtggattgcatacattagtcctaccagcagttccaagtactatgcggactctgtgaagggccgattcatcgtctcccgagacaacgccaagaaattacttttctgcaaatgaccaacctgagagacgacgacacggccttctatcactgtgcgagaggtcaaaaatggctgcaggtggcccgttggttcgacccctggggccagggaaccctggtcaccgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15460 JY8QFUQ01C1O5I productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVKGAGTTVNWFDIW in-frame - cctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15461 JY8QFUQ01AJGZ5 No results +15462 JY8QFUQ01DH00E productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 874 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [2.17.38.11] CAKDASRYYYNSYCDNW in-frame - gcctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15463 JY8QFUQ01DN3YF productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 821 85.97 190/221 nt 85.52 189/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARQLSGDYASFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtgaccccatcggcaacactgcttactcctGggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatgagttttccctgacactgacctctatgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +15464 JY8QFUQ01ARR3V unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 1 10 9 X 10.9.X [1.17.38.11] CTRGSSRGGRYDENYYELDF## out-of-frame - tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15465 JY8QFUQ01CC2EX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca +15466 JY8QFUQ01C69IF productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +15467 JY8QFUQ01AHLSP No results +15468 JY8QFUQ01BJDZ9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag +15469 JY8QFUQ01AMOSM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 923 91.74 200/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame - cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15470 JY8QFUQ01B89WK productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1009 93.86 214/228 nt 93.42 213/228 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [2.17.38.11] CARGSSRGERSDVNYYELDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctccgggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtCccccatcgagaggcctcgagtggctgggaaggacatactacaggtccaagtggtattatgactatgcagtgtctgtccaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagctgaattctgtgactcccgaggacacggctgtgtattactgtgcaagagggtccagccgcggggagagatctgatgtgaactactatgagctggacttctggggccagggaatcctggtcaccgtctcctcagcatcctcgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +15471 JY8QFUQ01DAUPX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDASRYYYNSYCDNL# out-of-frame - in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttaCtttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaatttgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15472 JY8QFUQ01C2L0Q unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 133 52.43 97/185 nt 8 7 X 8.7.X [1.17.28.X] null - No rearrangement found tctggattcaccttcagttctcacactatgaactgggtccggcaggctccagggaaggggccggagtgggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15473 JY8QFUQ01CAWNM productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 748 82.65 181/219 nt 82.19 180/219 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [2.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15474 JY8QFUQ01AWPYT unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 710 91.12 154/169 nt 8 7 X 8.7.X [1.17.22.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AWPYT ; 8 AA in Homsap_IGHV3-11*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatct +15475 JY8QFUQ01CNZ7K No results +15476 JY8QFUQ01A3AHC productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgggaactcag +15477 JY8QFUQ01DO2CA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGVIAVAG#DFDCW out-of-frame + cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagggggttatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15478 JY8QFUQ01DXFBE unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ4*03 F (see comment) 87 64.58 31/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CXRDSDSSGYARYDSMDVW# out-of-frame + Other possibilities: Homsap_IGHJ2*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatCgggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgngagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctgggggccaaagggaccgcggtcaccgtctcatcagcctccaaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactcag +15479 JY8QFUQ01BF9JF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 748 82.65 181/219 nt 82.19 180/219 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [2.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15480 JY8QFUQ01BFXYS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-13*01 F 1 8 7 16 8.7.16 [1.17.38.11] CAKTQPFGTTWYGATDAW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctgggtttacctttagcaactttgccatggcttgggtccgccaggctccaagaaaggggctggagtgggtctcagctattgctcgtggcggtgacacacactaccgagactccgtgaagggccgattcaccatctccagagacaattctaagaacacactgattctgcagatgagcagcctaagagccgaggacacggccttatattactgtgcaaagacgcagccgtttggcaccacctggtacggtgctacggatgcgtggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15481 JY8QFUQ01BAVEX No results +15482 JY8QFUQ01CBQCV No results +15483 JY8QFUQ01AFH1F unproductive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 1 8 7 X 8.7.X [2.17.38.11] CASSVFSPRR#FDYW out-of-frame + stop codons tttcgggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtccccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15484 JY8QFUQ01CE1X7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15485 JY8QFUQ01C5482 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 944 93.49 201/215 nt 92.56 199/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tctctggcgactccatcagtggtcactactggagctggatcaggcagccCcccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaaccCcctccctcaagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15486 JY8QFUQ01AOCIF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ6*02 F 212 87.27 48/55 nt 8 8 10 8.8.10 [1.17.38.11] CARDRYYVVDVW in-frame - cctctggattcaccttcagtgccacctggatgcactgggtccgccaagctccagggcaggggctggtgtgggtctctcatattaatggtgatgggagtagcacaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacggtgtatttgcaaatgaacagtctgagagccgaggacacggctgtatactactgtgcaagagatcgatactacgttgtggacgtctggggccaagggaccacggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15487 JY8QFUQ01CQST2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15488 JY8QFUQ01ALW5O productive Homsap IGHV3-11*01 F (see comment) 783 84.79 184/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVRDGARRTNQWLAHDFW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagctttaatgccttctatatgggttgggtccgccaggctccaggaaaggggctggagtggatttcgtacattaactctggtggtagtgacacatattacgcagactctgtgaagggccgattcaccatctccagggacaacgcctgggacacaatgtacttggaaatgaacagcctgagagccgaagacacggccgtctactattgtgtgagagatggcgctagaaggacgaatcagtggctggcccatgacttctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +15489 JY8QFUQ01BJQAH productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt 92.79 206/222 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 7 7 8 7.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 33 in the user submitted sequence), (cause frameshift) ctctgcagcctctggattcattgtcaatagcactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15490 JY8QFUQ01B20UU productive Homsap IGHV3-48*01 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt 8 8 7 8.8.7 [0.17.38.11] CARAPFDYW in-frame - tggattcatctttagtagctatagtatgaactgggtccgccaggctccagggaaggggccggagtgggtttcatacattagcggtagtagtagctccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcagatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagccccctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15491 JY8QFUQ01BWEYJ No results +15492 JY8QFUQ01AE8QV productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CIMDLVGRADYW in-frame + ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15493 JY8QFUQ01AX9OZ unproductive (see comment) Homsap IGHV3-11*01 F 833 87.16 190/218 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CVREVTGVWDW#FDPW out-of-frame + stop codons cctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggttttgacccctggggccggggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15494 JY8QFUQ01C0NN1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15495 JY8QFUQ01AT4NT productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 868 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.37.11] CAKDASRYYYNSYCDNW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 213 in the user submitted sequence), (cause frameshift) ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttattttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15496 JY8QFUQ01AH89D unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 872 89.77 193/215 nt 88.84 191/215 nt Homsap IGHJ4*03 F (see comment) 114 70.83 34/48 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDPRDYCSGGYCFVGAFDI# out-of-frame + Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaggaattattactggagctggatccggcagTcccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaaccCcctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaaggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +15497 JY8QFUQ01DD35D No results +15498 JY8QFUQ01DAUWI unproductive (see comment) Homsap IGHV4-61*02 F 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-15*01 F 2 10 7 X 10.7.X [1.17.37.11] CARDPQGYL*WW*LPLFC#MDVW out-of-frame + stop codons Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) ctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaaccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagacccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggccctatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccgtgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +15499 JY8QFUQ01CG66E productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +15500 JY8QFUQ01BIOGL productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15501 JY8QFUQ01BQAQL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaagaggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15502 JY8QFUQ01CJKY6 No results +15503 JY8QFUQ01AEU6X productive Homsap IGHV3-11*01 F 865 88.58 194/219 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARDGDADYGDLPIPFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctgaattcagtttcactgaccaccacatgagctggatccgccgggctccagggaaggggctggagtgggtgtcatacattagtcctacaggtagtgccatattttacgcagactctgtgaaggcccgtttcaccatctctagggacaacgccaagaatttactatatctacaaatgaacagcctgagacccgaggacacggccatctattactgtgcgagagatggggacgcggactacggtgacttgcccatccctttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15504 JY8QFUQ01BG290 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 859 88.89 192/216 nt 87.96 190/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 7 7 21 7.7.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) cctctggacgctccttgagaagctttggatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcagccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15505 JY8QFUQ01CNWM0 productive (see comment) Homsap IGHV4-34*10 F 791 85.58 184/215 nt 84.19 181/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'AA' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); tgtctggtgagtccttcactaattactactggagctggatccgccagtcccccaggaAAagggtctggagtggcttgggggAggtccatcatagtggacgcaccgactacaaccccGtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15506 JY8QFUQ01AN2OV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15507 JY8QFUQ01AQ0ZB unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame - cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15508 JY8QFUQ01BBDL1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.37.11] CVREGAATGSFYYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 156 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccaggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +15509 JY8QFUQ01CIZF1 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARLPNTIDSW in-frame + Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) ttctggatatagttttgccacctactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatgggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccgggtcaccatttcagccgacaagtccctcagtatcgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagactgcctaacactattgactcctggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15510 JY8QFUQ01BM11Z unproductive Homsap IGHV4-39*02 F 947 91.86 203/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 10 7 X 10.7.X [1.17.38.11] CARRYSWNYE##FDPW out-of-frame + tctctggtgactccatcagtactaataattactactgggcctggatccgccagcccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaacggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15511 JY8QFUQ01CR0Q8 productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15512 JY8QFUQ01A0FO5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccgag +15513 JY8QFUQ01DNG2W productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15514 JY8QFUQ01C5LS4 productive (see comment) Homsap IGHV4-34*10 F 823 87.04 188/216 nt 86.57 187/216 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [2.17.38.11] CARNTNYGGNSGDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gtgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaAagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15515 JY8QFUQ01CLQNM unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15516 JY8QFUQ01AHGEL No results +15517 JY8QFUQ01BP6JA productive Homsap IGHV3-11*06 F, or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-33*02 F or Homsap IGHV3-33*03 F or Homsap IGHV3-48*03 F or Homsap IGHV3-48*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F 165 68.35 54/79 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD4-23*01 ORF 3 X X 12 X.X.12 [X.X.26.11] CARGTSVDPGIDHW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtaattattggatgcactggatgaacagcctgagagccgaggacacggctgtctactactgtgcgagagggacctcagtggacccggggattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15518 JY8QFUQ01CF38L unknown (see comment) Homsap IGHV3-21*04 F 851 88.07 192/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaacccgtggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcaccctctgggggcacagcggccctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15519 JY8QFUQ01C160X productive (see comment) Homsap IGHV4-61*02 F 947 92.31 204/221 nt 91.86 203/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcGatcgcacgcaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15520 JY8QFUQ01ADNO5 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame - tctctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15521 JY8QFUQ01BZ0P1 unknown (see comment) Homsap IGHV3-16*01 ORF 94 53.45 62/116 nt 8 X X 8.X.X [25.5.X.X] null - No rearrangement found cctctggattcacctttagtagttctgccatgaactggaggagtctgggggaggcttggttcagccgggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15522 JY8QFUQ01BVQT2 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 842 87.61 191/218 nt 87.16 190/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKQKS*LW#YYFDQW out-of-frame + stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacgtttaaaacacatgccatgagctgggtccgccaggctccaggaaaggGggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaaatcatagttatggatactactttgaccagtggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccgaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +15523 JY8QFUQ01CYPTR unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARXNYGDYW# out-of-frame - in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaaganataattacggtgactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15524 JY8QFUQ01CDH8H No results +15525 JY8QFUQ01BZPY8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 2 8 8 9 8.8.9 [1.17.38.11] CARDNYGDYWG in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15526 JY8QFUQ01DGWTB productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + cctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatnggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaccggtgacggtgtcgtggaactcagg +15527 JY8QFUQ01CH0TM No results +15528 JY8QFUQ01A8ML0 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 7 8 15 7.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) gtctggattcatcttcttgaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15529 JY8QFUQ01B7WRW productive (see comment) Homsap IGHV3-7*01 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 151 76.47 39/51 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.37.11] CGRDERGADLPXDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 191 in the user submitted sequence), (cause frameshift) cctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagcccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaangattcctggggcctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15530 JY8QFUQ01BOXEZ productive (see comment) Homsap IGHV1-3*01 F 876 90.19 193/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagCaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15531 JY8QFUQ01A8U3A productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaGggggctggtgtgggtctcacgtactaacaCcgggggggactaacacagcctacgcgcactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15532 JY8QFUQ01CL9Y8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD2-21*02 F 3 8 8 20 8.8.20 [1.17.38.11] CAKEGDGSVIPSPVPEWQFDSW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttgacagccatgccatgcactgggtccgtcgggctccagggaaggggctggagtgggtctcggcagttagtggtggtggccattatacatactacgcgcgctccgtgaagggccgatttaccatatccagggacaattcccgaaacatggtgtatttggagatgactggcctgacagccgaggacacggccgtatattattgtgcgaaagagggagacggatcagtgatcccgtctcctgttcctgagtggcaatttgactcctggggccagggaaccctggccacggtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +15533 JY8QFUQ01BJ5AZ No results +15534 JY8QFUQ01BF0B7 No results +15535 JY8QFUQ01CJGZM No results +15536 JY8QFUQ01AJ2OA productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15537 JY8QFUQ01AL17I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcagtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtccgtggaactcagg +15538 JY8QFUQ01B9UYL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1085 100.0 218/218 nt 99.08 216/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKDRITIFSYNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'T' (1 nucleotides at position 65 to 65 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctTggagtgggtctcagcGtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15539 JY8QFUQ01AW4CK productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15540 JY8QFUQ01CUROA productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 856 88.13 193/219 nt 86.76 190/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [3.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 19 to 20 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 38 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) aggcctcctggattcaccCTttgggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15541 JY8QFUQ01B69U3 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 872 87.5 196/224 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD1-14*01 ORF 1 8 10 X 8.10.X [1.17.38.11] CTADVPSPLAQNDF# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcactttcaatggcgcctggatgaactgggtccgccaggctccagggaagggtctggagtgggttgcccgtataaaaacttttggtgaaggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcaaaaaaagggctgtatctgcagatggacagcctgagaatcgaggacacagccaagtattactgcaccgcagatgtcccgtcaccattagcgcaaaatgacttctgggccagggaaccctggtcaccgtctcctcagnatccccgaccagccccaaggtcttcccgctgagcctcgaagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga +15542 JY8QFUQ01B6YXV productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15543 JY8QFUQ01CTUWH unknown (see comment) Homsap IGHV3-7*03 F (see comment) 733 81.94 177/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (81,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggaggggcgtggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15544 JY8QFUQ01AWXID productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 896 89.91 196/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 9 7 12 9.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'GTG' (3 nucleotides at position 22 to 24 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 34 of V-REGION: 3 nucleotides (from position 21 in the user submitted sequence), (do not cause frameshift) tctctggtggctccatcaacaGTGgtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaaccCcgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgcgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +15545 JY8QFUQ01CKVV0 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15546 JY8QFUQ01A5FLW productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15547 JY8QFUQ01BDK06 unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 874 93.03 187/201 nt 92.54 186/201 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-2*01 F 2 10 1 X 10.1.X [1.17.37.11] CARVA*CDLW*SQLLKAL#YSYDMDVW out-of-frame - stop codons in CDR2-IMGT, from codon 57 of V-REGION: 19 nucleotides (from position 90 in the user submitted sequence), (cause frameshift) ctctggtggctccatcaacaatagtacttactactacggctgaatccgccagccccccgggaaggggctggagtggattgggagtctctctacaacccgtccctcatgagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgccgacacggctgtatatcgctgtgcgagagttgcctgatgtgatttgtggtagagccaactgctcaaggccttagtactcctacgatatggacgtctggggccaagggaccacggacgccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15548 JY8QFUQ01BA7JM productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15549 JY8QFUQ01C1TLO No results +15550 JY8QFUQ01CFE76 No results +15551 JY8QFUQ01A857F productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 806 85.78 187/218 nt 85.32 186/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); cctctggattcGaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15552 JY8QFUQ01AB599 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag +15553 JY8QFUQ01A3YE7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15554 JY8QFUQ01CA8OU productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 777 85.05 182/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*02 F 3 8 8 15 8.8.15 [0.17.38.11] CGRGQHIVVVTSKIDLW in-frame + tggatataccttcacctcctactatatctactgggtgcgacaggcccctggacagggactagagtggatgggacaagtcgaccctaatgacgggagaacaaagtacgcacagaagttcgagggccgggccaccgtgaccttcgacaggtccacgagcacagcctacatggagctgagtagcctgagatctgacgacacggccgtgtattattgtggcaggggtcagcacattgtagtggtgactagtaagattgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +15555 JY8QFUQ01C6GOS productive (see comment) Homsap IGHV4-39*03 F 924 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); ctccggtggctccatcaacagtagaaAattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgaccggtgtcgtggaactccag +15556 JY8QFUQ01CTPUF productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*08 F (see comment) 755 83.72 180/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 1 8 7 13 8.7.13 [1.17.38.11] CASVRPSGERFFDFW in-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggctcgctcacgggtttcaagtggggctggatccggcagcccccagggaagggactgcaatggattggacatatctctttcgttggggacaccagttatgacccttccctcagaagtcgagtcgccctttcagtcgacacgtccaagaaccagttctccctgaaactgaactctgtgactcctgcggacacggccgtctattactgtgcgagcgtgcgtccttcgggagaacggttcttcgacttctggggcctgggaaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15557 JY8QFUQ01DCHH0 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 950 93.12 203/218 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 7 10 9.7.10 [1.17.38.11] CASHGGKYFPQW in-frame + tctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggacaaatccatcatggtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15558 JY8QFUQ01ACLJ7 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15559 JY8QFUQ01BZI5Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtgcgtggaactca +15560 JY8QFUQ01B03TR productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1032 96.82 213/220 nt 96.36 212/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 164 81.63 40/49 nt Homsap IGHD2-21*02 F 3 8 8 7 8.8.7 [2.17.38.11] CARMTDDFW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); agtctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagcagtagcaccatCaaaatacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtgcgagaatgacagacgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15561 JY8QFUQ01B0V5U No results +15562 JY8QFUQ01DEO1E productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 775 84.02 184/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15563 JY8QFUQ01CXZ92 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [2.17.38.11] CARPGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) tgttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacctgggcaactcgctcttgactactggggcgagggaaccctgattttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15564 JY8QFUQ01CNPN6 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); cctccggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaGggggccggtgtgggtctcacgtattaatgaagacgggCagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15565 JY8QFUQ01BQLNQ productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); gttctggaGtacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15566 JY8QFUQ01C3D0P unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*04 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*03 F or Homsap IGHV3-66*04 F (see comment) 269 72.64 77/106 nt 8 7 X 8.7.X [1.17.1.X] null - No rearrangement found Low V-REGION identity (72,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggcttcaccgtcaataacaactacatgggctgggtccgccaggctccagggaaggggctggagtgggtcatcgcctgcctggtccagggcttcttccccca +15567 JY8QFUQ01DP4QQ No results +15568 JY8QFUQ01B7L34 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctncctggtcaaggactcanttccccgaaccggtgacggtcgtgcgtggaactcag +15569 JY8QFUQ01CX9UQ No results +15570 JY8QFUQ01BY8JZ unproductive Homsap IGHV3-72*01 F 1088 98.66 221/224 nt Homsap IGHJ6*04 F (see comment) 108 66.67 36/54 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYDP## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15571 JY8QFUQ01CTEB2 unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 94 84.62 22/26 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found tccgggggacagtgtctctaccaaca +15572 JY8QFUQ01CABSX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15573 JY8QFUQ01BLFO0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 229 73.33 66/90 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 X X 14 X.X.14 [X.X.30.11] CAKEEGATGVYYVDHW in-frame - Low V-REGION identity (73,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcacctttaccacctccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15574 JY8QFUQ01DGVTM No results +15575 JY8QFUQ01AZMOO unproductive Homsap IGHV1-8*01 F, or Homsap IGHV1-8*02 F 1011 97.2 208/214 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [0.17.38.11] CARGVRTVVTALSYGMDV## out-of-frame + tggatataccttcaccagatatgatatcaattgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaacagtggtaacacaggctatgcacagaagttccagggcagagtcatcatgaccaggaacacctccataagcacagcctacatggagctgagcagcctgagttctgaggacagggccgtgtattactgtgcgagaggtgtccgaacggtggtgactgctctttcctacggtatggacgtctggggcccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaaggatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15576 JY8QFUQ01CYSU0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 932 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRWKMDRSGVSAAATDVFGMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctcgggattcaccttcagtggctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatggtaagaataaatacatctactatgcagactcactgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaccaacctgagagccgaggacacggctctatattactgtgtgagatggaagatggataggagtggtgtaagtgcagcggcaacagacgttttcggtatggacgtctggggccaagggaccacagtcaccgtctcctcagcctccaccaagggctcatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactc +15577 JY8QFUQ01C825R productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcttggaactca +15578 JY8QFUQ01ALAFA unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 418 96.63 86/89 nt 8 3 X 8.3.X [1.17.X.X] null + No rearrangement found ctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagta +15579 JY8QFUQ01DO5NY productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1005 95.45 210/220 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARGPRSRGYGMDVW in-frame - agcctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15580 JY8QFUQ01CTEIK No results +15581 JY8QFUQ01AO14S productive Homsap IGHV3-7*01 F 1011 97.2 208/214 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [0.17.38.11] CSNGYGDFPRRW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggattcaccttcaggagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgacaaattctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15582 JY8QFUQ01C9HGQ unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 138 52.69 98/186 nt 8 7 X 8.7.X [1.17.28.X] null + No rearrangement found ctctggattcaccttcagttctcacactatgaactgggtccggcaggctccagggaaggggccggagtgggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15583 JY8QFUQ01AMXZ6 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 867 89.72 192/214 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + tcgggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15584 JY8QFUQ01CSU1I productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 666 78.34 170/217 nt 77.42 168/217 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.16.38.11] CAREDIVREGLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (78,34% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tgtctggtggctccatcgccacttatcattggtggAacttgggtccgccagaccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15585 JY8QFUQ01C7775 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 389 75.54 105/139 nt 8 8 X 8.8.X [1.17.11.X] null - No rearrangement found Low V-REGION identity (75,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15586 JY8QFUQ01BBQPA productive (see comment) Homsap IGHV1-2*02 F (see comment) 750 83.18 178/214 nt 82.71 177/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARGLSYDSSPYWGYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'GA' (2 nucleotides at position 52 to 53 in the user submitted sequence), (cause frameshift); tggatacatcttcaatgacttctacatatattgggtgcgacaggcccctggGAcaaggggcttgagtggatgggatggttcaaccctaatagtcgtgtcacagactatgcagagaaatttcagggcagggtcaccatgaccggggacccgtcccgcagcacagtccacctgaaactgacccgcctgaagtcggacgacacggccgtctattactgcgcgagaggtctctcctatgacagtagtccttattggggctactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15587 JY8QFUQ01CXGJG productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 281 81.4 70/86 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame - Low V-REGION identity (81,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15588 JY8QFUQ01DAR6E No results +15589 JY8QFUQ01C3CCF productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 924 91.36 201/220 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 10 7 18 10.7.18 [1.17.38.11] CARSAYCGADCYSADYLQHW in-frame + ctctggtggctccgtcagcagtaggggttactactggaactggatccgccagttcccagggaagggcctggagtggattgggaacatcttttacagtgggggcacctacgacaacccgtccctcaggagtcgaatttctatatcattagacacgtctaagaaccaattctccctgaagttgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcacgcacccagccagatgggaacgtgtcatcgcctgcctggtccagggcttcttccc +15590 JY8QFUQ01BO1TD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.89 192/216 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) tctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15591 JY8QFUQ01BEZH7 unproductive Homsap IGHV3-7*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccgag +15592 JY8QFUQ01CQJD2 productive (see comment) Homsap IGHV3-48*01 F 1095 100.0 220/220 nt 99.55 219/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.17.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtagctatagcatgaactgggtccGgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15593 JY8QFUQ01AZO8K No results +15594 JY8QFUQ01BSAMC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15595 JY8QFUQ01C8X0V productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaagccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +15596 JY8QFUQ01BQPM7 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CARLGARFGD#DYW out-of-frame - stop codons in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15597 JY8QFUQ01AST77 No results +15598 JY8QFUQ01BZ99I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15599 JY8QFUQ01AP9Y7 productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 876 90.19 193/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [0.17.38.11] CATDRCTGGTCCPHYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacactttcaccagttattatatacactgggtgcgacaggCcccctggacaggggcttgagtggatgggagttgtcaaccctggtgctgaatacacactctacgcacagaagttccagggcagactcaccttgaccagggacacgtccacgagcacagtctacatggagttgagtagcctgagatctgaggacacggccctgtattactgtgcgacagataggtgtactggtggtacctgctgtccacattactggggccagggaaccctgatcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15600 JY8QFUQ01C5U4M productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 972 94.47 205/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD1-26*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARVGELQYWHFDLW in-frame + gtctggattcacctttggtgattatggcatgagctgggtccgccaagctccagggaaggggctggagtgggtctctggtattaattggattggcagtggtacaggttatgcagattctgtgaggggccgattcaccatctccagagacaacgccaagaactccctgtatctacaaatgagcagtctgagagccgaggacacggccttgtatcagtgtgcgagagttggggagctacaatactggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15601 JY8QFUQ01ABSM6 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +15602 JY8QFUQ01C79YW unproductive Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 651 78.04 167/214 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt 8 8 X 8.8.X [0.17.38.6] RTGD (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Low V-REGION identity (78,04% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15603 JY8QFUQ01CCGPP productive (see comment) Homsap IGHV3-33*03 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [2.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) gcgtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15604 JY8QFUQ01B84I1 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15605 JY8QFUQ01A2YKB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 951 92.73 204/220 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gccgtctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtg +15606 JY8QFUQ01CWQ1B productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15607 JY8QFUQ01B7MKI productive Homsap IGHV4-61*08 F (see comment) 827 87.44 188/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKNNNDFGDYDWFDPW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (8 AA in JY8QFUQ01B7MKI ; 10 AA in Homsap_IGHV4-61*08) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggctccctcgggggtttcgcctggagttggatccggcagcgcccgggaaagggactggaatggattggacatatctctcacatcgggagctccaactatgagccctccctcacgagtcgactcaccatgtcagtagacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15608 JY8QFUQ01CD9VK productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ6*02 F 121 66.13 41/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); ggttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcCccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggccaagggactacttccccgaaccggtgacggtgtcgtggaactcag +15609 JY8QFUQ01CYAT8 productive (see comment) Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 743 82.49 179/217 nt 81.57 177/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 3 10 6 15 10.6.15 [1.17.37.11] CARVWVAGSRDENFDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 162 in the user submitted sequence), (cause frameshift) ctcgggtgcttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtggggcacctattacaacccgtctctcaagagtcgacttgccctgtcattagacgcgtctaataatgtttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15610 JY8QFUQ01CGGQ6 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKVSGNSRTYWYLDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacaactttcccagatattggatcgcctgggtgcgccagattcccgggagaggcctggagtgggtggGggatgatctatcctggtgactctgagaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacgcgtccatgaacaccgcctacctgcagtggagcagcctgaaggcctccgacaccgccatatacttctgtgcgaaggtctctggtaactctcgaacctactggtacctcgatatctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15611 JY8QFUQ01CEC9H No results +15612 JY8QFUQ01AMKH6 unproductive Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [0.17.38.11] CARGPVSGWYTDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggcccagggaaccctggtcaacgtctcatcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacacgcacccccaaggcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15613 JY8QFUQ01B9U1R No results +15614 JY8QFUQ01BUYQ1 productive (see comment) Homsap IGHV3-7*01 F 1030 97.69 211/216 nt 97.22 210/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.16.38.11] CVSSPYFYDSNGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15615 JY8QFUQ01CFP87 productive Homsap IGHV1-2*02 F 921 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 1 8 8 12 8.8.12 [0.17.38.11] CATDVPAGQLWGYW in-frame - tggatacacattcaccgacaactatatgcactgggtgcggcaggcccctggacaggggcttgagtggatgggatggatcgaacctaacagtggagacacaaactatgcacaaaagtttcagggcagggtcaccatgacgagggacacgtccatcgccacagcctacatggagttgagcaggctgagagctgacgacacggccgtgtactactgtgcgaccgacgtccccgcagggcaactctggggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15616 JY8QFUQ01AKND1 No results +15617 JY8QFUQ01DREWH No results +15618 JY8QFUQ01CV650 unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [0.17.38.11] CAMGGALCGGDR*#FDYW out-of-frame - stop codons in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tggatacagttttaccacctactggatcggctgggtgcgccagatgcccgggaAaaggcctggagtgggtgggaattatatctcctggtgactctgaaatccgatacagcccgtccttcgaaggccaggtcaccatctcagccgacaagtccaccagcaccgcctacctgcagtggaacaccctgaaggcctcggacactgccatgtattattgtgcgatggggggggcactttgtggtggtgacaggtagatttgactattggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15619 JY8QFUQ01DGD7Q productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 897 90.0 198/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag +15620 JY8QFUQ01DCK52 unproductive Homsap IGHV3-7*01 F 841 87.96 190/216 nt 87.5 189/216 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.37.11] CGRDERGADLPNDS## out-of-frame + in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 190 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagcccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctggggccctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15621 JY8QFUQ01AYJ9K productive Homsap IGHV1-3*01 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15622 JY8QFUQ01B4FSE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [2.16.38.11] CAKRLQAVADDAFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) gcctctggattcatctttagtagctatgccatgggctgggtccgccagGgctccagggaaggggctgagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgagcagcctgagagccgaagacacggccatatattactgtgcgaaaaggttgcaagcagtggctgatgatgcttttgatttctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15623 JY8QFUQ01AQ3NT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15624 JY8QFUQ01BA3GM unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ1*01 F 152 76.92 40/52 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [1.17.38.11] CTRVGTFNWF#PW out-of-frame - in CDR2-IMGT at codon 62 of V-REGION: 'T' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); ctctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatTgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +15625 JY8QFUQ01AN075 No results +15626 JY8QFUQ01BLVIV productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15627 JY8QFUQ01DNJ91 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15628 JY8QFUQ01AMSZ1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcaggc +15629 JY8QFUQ01BX0V1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDRYPRSTAITAPDY## out-of-frame + cctctggattcccctttagcaactatgccatgacctgggtccgccaggctccaggggagggactggaatgggtctcaagtattagaggtagtggtgacaggacatcctacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagctgaacaacctgagagccgaggacagggccgaatattactgtgcgaaagatcgctaccctcggtcgacagctattacagcgcctgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +15630 JY8QFUQ01AXQWW unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*02 F 2 8 8 X 8.8.X [1.17.38.11] CARDRRGIVMK#DYW out-of-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15631 JY8QFUQ01DNXAW productive (see comment) Homsap IGHV3-7*01 F 874 89.04 195/219 nt 88.58 194/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 79 62.0 31/50 nt Homsap IGHD3-3*01 F 1 8 8 11 8.8.11 [2.17.38.11] CVRPPRPCFRYLG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 169 to 169 in the user submitted sequence), (cause frameshift); gccaatggattcacctttagtgactattggatgagttggttccgccaggccccagggaaggggccggagtgggtggccaacataaacgaagatggatctgggcaacagtatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgCtttttagaaatgaacagcctgagaatcgacgacacggctgtgtattactgtgtgagaccccccagaccgtgctttagatatctgggggccaggggggcagtggtcaccgtctcttcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatggggaacgtggtcgtcgcatgcctgggtccaggggcttctttccccc +15632 JY8QFUQ01CLFQD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15633 JY8QFUQ01B8BYY unproductive (see comment) Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-15*01 F 2 10 7 X 10.7.X [1.17.38.11] CARDPQGYL*WW*LPLFC#MDVW out-of-frame - stop codons Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaacccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagacccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15634 JY8QFUQ01AW5SW unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CTKRLSGRPLVESGAP#FFDDW out-of-frame + stop codons cctctggattcacctttagcgactatggcatgagttgggtccgccaggctccagggaagggactggagtgggtctcaagtattatcgctaatggtggtgacacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagatgaacagccttagaggcgaggacacggccgtatattattgtacgaaaagactatccggacggccgcttgttgaatcaggtgcgccccttctttgacgactgggaccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15635 JY8QFUQ01CXFOY unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDY## out-of-frame + cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggcccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15636 JY8QFUQ01BDDL7 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [2.17.38.11] CARHLLGDPFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); gggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagaCtacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgagacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15637 JY8QFUQ01A71MM No results +15638 JY8QFUQ01CLEH3 productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 984 95.79 205/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CASAPSDSSGYYFSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagttactatatgcactgggtccgacaggcccctgGgacaagggcttgagtggatgggaatgatcaaccctagtggcggaagcacaatctacgcacagaacttccagggcagagttgccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgctagcgccccctctgatagtagtggatactacttttcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15639 JY8QFUQ01A9G63 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKESLVRGVISYYFDDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) cctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggtttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctggttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtcatcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagg +15640 JY8QFUQ01BX7EL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 111 53.19 75/141 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found cctctggattcacctttagtagttctgccatgaactggaggagtctgggggaggcttggttcacggcggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15641 JY8QFUQ01CQF8T No results +15642 JY8QFUQ01C277Q productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15643 JY8QFUQ01A2UOO unproductive (see comment) Homsap IGHV1-69*05 F (see comment) 235 73.12 68/93 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 1 X X 14 X.X.14 [X.X.31.11] CATSFGKISTPYFEHW in-frame - stop codons Low V-REGION identity (73,12% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cggacacaccctcattgaattgtccatgcactggacacagcctacatggagctgagcagcctgacatctgacgacacggccgtgtattactgtgcaacatcattcgggaagatttcaactccctactttgaacactggggccagggaaccctggtcagcgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15644 JY8QFUQ01B6FD5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15645 JY8QFUQ01DNN2A unproductive (see comment) Homsap IGHV3-7*01 F 922 92.13 199/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CVRG*RWCQFWRN#DYW out-of-frame - stop codons tctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgagggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15646 JY8QFUQ01B5FEA productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15647 JY8QFUQ01BQBSK unproductive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDGSAIPVTGTYFEY## out-of-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccaggggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc +15648 JY8QFUQ01AW0RY unproductive (see comment) Homsap IGHV1-18*01 F 983 95.77 204/213 nt 94.84 202/213 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [X.17.38.11] CARGL*G#YSYGMDVW out-of-frame - stop codons in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); aggtacacctttaccagctatggtattagctgggtgcgacaGggcccctggacCaagggcttgantggatgggatggatcagcgtttacaatggtaacacaaactatgcagagaagctccagggcagagtcaccatgaccacagacagatccacgagaacagcctacatggagttgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagggctctagggggctactcctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15649 JY8QFUQ01AK4AI productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 930 91.03 203/223 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 10 14 8.10.14 [1.17.38.11] CTTRPRGWEPLGLDYW in-frame + ctctggattcactttcagtgacgcctggatggtctgggtccgccaggctccagggaaggggctggagtgggttggccttattaagaccaaacctgatggttggacaacaatctactctgcacccgtgaaaggcagattcatcatttcaagagatgattcaaaaaacatggtgtttctgcaaatgaacaacctgagaaccgaggacacagccctttattactgtaccacacggccccgggggtgggaaccacttggccttgactactggggcctgggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15650 JY8QFUQ01BGKIP productive Homsap IGHV3-30*01 F 942 92.27 203/220 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [2.17.38.11] CVKNDLSWGTIEHYFDYW in-frame - agcctctggattcacgttcaacatttatggtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15651 JY8QFUQ01AVFZ6 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15652 JY8QFUQ01CA8KR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 726 81.36 179/220 nt 80.91 178/220 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 17 8.8.17 [2.17.38.11] CAKVKGYGGNWFQPHFDRW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,36% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); agtctctggattcTgccttcgaggggtctgtcgtgacctgggtccgacaggctccagggaaggggctggagtgggtctcaggtatctacggtggtgatggtacatcattttacgcagacttcgcgaagggccgattcaccgtctccagagacaattccaaggacacggtctatctgcagatgaacggcctgagagtcgaagactcggcccgttattattgtgcgaaagtgaagggctacggcggcaattggttccagcctcactttgaccgctggggccagggcaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15653 JY8QFUQ01DVIY1 No results +15654 JY8QFUQ01APJF5 unproductive Homsap IGHV3-48*02 F 483 86.15 112/130 nt Homsap IGHJ5*01 F 102 66.67 34/51 nt Homsap IGHD1-1*01 F 3 X 5 X X.5.X [X.X.38.11] CASGGKERLRSTTGLLSRHGRL# out-of-frame - ctctggactcaccttcagcagctataactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagtgggggaaaggaaagactacgaagtacgacgggactactatcacggcatggacgtctgggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +15655 JY8QFUQ01A8Y8J productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD2-8*02 F 2 8 8 24 8.8.24 [1.17.38.11] CVRAAGYCPGGDDCYKIGTHDSLDIW in-frame - gtctggattcaccttcagtacctatggcacacattgggtccgccaggctccaggcaaggggctggactgggtggcagttagttggcatgatggaagtcaggaatattatgcagactccgtgaggggccgattcactgtctccagagacaattccaagaacacggcatatctgcatatgaatgtcctgagaggcgaagacacggctgtctactactgtgtgagagcggcggggtactgtcctggtggtgatgactgctacaagatcggaactcatgactcccttgatatctggggccgaggggcagttgtctccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15656 JY8QFUQ01DM0RC unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 806 85.78 187/218 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDSDSSGYARYDSMDV## out-of-frame - Other possibilities: Homsap_IGHJ2*01 (shorter alignment but highest percentage of identity) cctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctgggggccaagggaccgcggtcaccgtctcatcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15657 JY8QFUQ01B2F7W No results +15658 JY8QFUQ01AQED1 productive Homsap IGHV1-3*01 F 948 93.93 201/214 nt Homsap IGHJ1*01 F 206 88.46 46/52 nt Homsap IGHD5-12*01 F 3 8 8 12 8.8.12 [0.17.38.11] CARPGYGDNYFHHW in-frame - tggattcaccttcactgactatgctatgcattgggtgcgccaggcccccggacaagggcttgagtggatgggatggatcaacgctggcaatggaaacacaaaatattcactgaagttccagggcagagtcaccattaccagggacacatccgcgagcacagcctatctggagttgactagcctgagatctgaggacacggctgtatattactgtgcgcgccctgggtacggtgacaattatttccaccactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15659 JY8QFUQ01AQSR8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD2-8*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDGQRYCSNGVCSSF#YSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctggattcacctacagcagcGtatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcgcagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15660 JY8QFUQ01B0V4X productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagagcccatcggtcttccccctggcaccctcctccaaagagcacctctggggggcacagccggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +15661 JY8QFUQ01BSGWN productive Homsap IGHV3-48*02 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARDMIIFGGALDNW in-frame - tggattcgccttcagtagttccagcatgaactgggtccgccagggtccagggaaggggctggagtggatttcacacattaggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggagcccttgacaactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15662 JY8QFUQ01BY4MW productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 897 90.0 198/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15663 JY8QFUQ01AFJGI unproductive (see comment) Homsap IGHV4-55*03 P, or Homsap IGHV4-55*09 P (see comment) 376 63.35 140/221 nt 62.44 138/221 nt Homsap IGHJ4*02 F 91 64.58 31/48 nt Homsap IGHD3-16*01 F 1 8 7 X 8.7.X [4.17.38.11] CTRGSLTGTYPSDPX# out-of-frame + stop codons The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (8 AA in JY8QFUQ01AFJGI ; 9 AA in Homsap_IGHV4-55*03), and low V-REGION identity (63,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'GG' (2 nucleotides at position 66 to 67 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'TCTGAG' (6 nucleotides at position 102 to 107 in the user submitted sequence), (do not cause frameshift); ttcggagacgatatatctggagacagtgttacttgggaactggatcagggcagtcccccaggggaGGggggcttgagtggctcgggcgtatctttcacaggTCTGAGtggcataccgactacttggcgtctgttagaggccgaatctccatggatgtcgacacgtccaagaaccacttcaccctgcagctccgctctctgactcccgacgacacggctacatatttctgtacaagaggctctctaactgggacatatccttctgacccantggggtctggggcaccccagtgaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttccccc +15664 JY8QFUQ01ARRMJ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15665 JY8QFUQ01COA9P productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [2.17.37.11] CVKGWNYHSATFGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 78 of V-REGION: 1 nucleotides (from position 141 in the user submitted sequence), (cause frameshift) gcctctggattcacctttagtgactatgccataagctgggtccgccaggctccaggaaaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccatttcagagacaactccaaagacacgctgtatctgcaaatgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaacctttgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15666 JY8QFUQ01CLNQ1 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15667 JY8QFUQ01BJ0OV productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); tctggattcaccttcagGtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15668 JY8QFUQ01B2RVH No results +15669 JY8QFUQ01B0CZW unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15670 JY8QFUQ01B8F4K unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt +15671 JY8QFUQ01ATVSF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.37.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 106 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15672 JY8QFUQ01CEJWZ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15673 JY8QFUQ01AKFJR productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); cctctggattGcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaataCcgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc +15674 JY8QFUQ01CFP7H productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15675 JY8QFUQ01DTDBD productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-11*01 ORF 3 8 8 16 8.8.16 [1.17.38.11] CARDRESTVTTRLDSDHW in-frame + ctctggattcaccttcgacagttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccatcagtagaagtagtagttacatatattacgcagactcagtgaagggccggttcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagacccggggacacggctatatattactgtgcgagagaccgggagtctacagtgactacgcgtctggactccgatcactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15676 JY8QFUQ01DMIUH productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1017 96.77 210/217 nt 96.31 209/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 3 7 8 20 7.8.20 [1.17.38.11] CARLPYIVVLTNIISPTYFDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) tttctggatacagtttaccagttactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctgctgactctgataccagatacagcccgtccttccaaggccaggtcagcatctcagccgacaagtccatcgacaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgcggctgccatatattgtggtgctgactaatataatctccccaacctactttgacttctggggccagggaacccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15677 JY8QFUQ01B95ZV productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASDLGGQKSYW in-frame - ctcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15678 JY8QFUQ01AT6GX productive Homsap IGHV3-9*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDRKGSNWYYFENW in-frame + ctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttcccccaa +15679 JY8QFUQ01AD8Y1 productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*03 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CARDEIPWDTIEYYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcactacatattccatgcactgggtccgccaggctccaggcaaggGggctagaatgggtggcagttatatcatatgatggaaaaaaaaagtcttatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtacctgcaaatggacagcctgaggcctgaagacacggctgtgtattactgtgccagagatgagatcccttgggatacaatagagtactactttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15680 JY8QFUQ01AVP9X unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctgggggccagggaacccgaggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15681 JY8QFUQ01B34Y6 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 794 84.62 187/221 nt 83.71 185/221 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-3*01 F 1 10 7 X 10.7.X [1.17.38.11] CARHRSFGVIIVNYFES## out-of-frame + Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tttccggtgactccatcaccagtactaattattactgGgggctgggtccgccagTcccccagggaagggtctggagtggattggaagtgtctattatcgggggacccagtacctcaacccgtctctccacaatcgagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtcttttggagtgataattgttaactactttgagtcctgggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +15682 JY8QFUQ01DN8AR productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 894 91.12 195/214 nt 90.19 193/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [0.17.37.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 71 of V-REGION: 1 nucleotides (from position 119 in the user submitted sequence), (cause frameshift) tggagtacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgGgggatcatctatcctggtacctctgagaccagatacagcccgtccttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15683 JY8QFUQ01BC8E3 productive (see comment) Homsap IGHV3-48*03 F 859 88.89 192/216 nt 87.96 190/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 7 8 13 7.8.13 [1.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 28 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagttcttatgcatgaactgggtccgcctggttcaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +15684 JY8QFUQ01ARJL7 unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt 10 7 X 10.7.X [1.17.38.X] null - No rearrangement found ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcgggccaactactgggggcccaggggaaccctgggtcaccgtctccctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15685 JY8QFUQ01CKEJT No results +15686 JY8QFUQ01C45M6 productive Homsap IGHV4-61*02 F 867 87.89 196/223 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 11 10.7.11 [2.17.38.11] CARSGWDNQFDFW in-frame - tgtctctggtgtcgccaccagtagtggcacttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaacccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgcccggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15687 JY8QFUQ01AYGE6 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 878 89.45 195/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) gcctcctggattcacCctttggttattatggcatggactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15688 JY8QFUQ01DH1ZV No results +15689 JY8QFUQ01CR20C No results +15690 JY8QFUQ01BFS9F productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctcggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +15691 JY8QFUQ01B1466 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 710 91.12 154/169 nt 8 7 X 8.7.X [1.17.22.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01B1466 ; 8 AA in Homsap_IGHV3-11*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatct +15692 JY8QFUQ01B1INU productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 930 91.03 203/223 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [1.17.38.11] CTTAPSETYATEYFAMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15693 JY8QFUQ01CGPC7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CIMDLVGRADYW in-frame + ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca +15694 JY8QFUQ01A1ALH productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15695 JY8QFUQ01AUD41 productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15696 JY8QFUQ01BO1BF productive Homsap IGHV4-59*02 F 962 94.42 203/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 3 8 7 17 8.7.17 [1.17.38.11] CARHSMGVTIVRGHWFDPW in-frame + tctctggtggctccgtcagcagttattactggagctggatccgacagcccccagggaagggactggagtggattggctatatccatgacagtgggagcagcaactacaacccctccctcaagagtcgagtcaccatatctgtggacacgtccaagaaccagttctccctgaagctgacttctgtgaccgctgcggacacggccgtatattactgtgcgagacattctatgggtgttactatagttcggggacactggttcgacccctggggccagggaaccctggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15697 JY8QFUQ01DBZUC productive (see comment) Homsap IGHV3-7*01 F 937 94.29 198/210 nt 93.33 196/210 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 7 8 14 7.8.14 [X.16.38.11] CARGSYYYYDTNGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) atttacctttacaaattattggagagctgggtccgccaggctccagggaTgggggctggagtgggtggccagcgtaaaacaagatggaggtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggtcctactattattatgatactaatggcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15698 JY8QFUQ01AX3MM productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 3 7 8 18 7.8.18 [1.17.38.11] CASLNTHAGPGAERSAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 23 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtaacacagaatgaattgggtccgtcaggctccagggaaggggctcgaatgggtctcgtccattaccagttccagtagttacatatactacgcagactcggtgacgggccgattcaccatctccagagacaacgccaaggggtcactctatctgcacatgagctaccttagagccgaggacacggctgtctattactgtgcgagcctaaacacgcacgcgggaccgggagccgaaaggtctgcttttgatatctggggccaagggacaatggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15699 JY8QFUQ01AGPYP productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 836 87.91 189/215 nt 86.98 187/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 7 8 17 7.8.17 [1.17.37.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 71 of V-REGION: 1 nucleotides (from position 118 in the user submitted sequence), (cause frameshift) ctctggattcagtttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcatgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15700 JY8QFUQ01AXHTR unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 186 97.44 38/39 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found cctctggattcatcttcagtagctactggatgcactggg +15701 JY8QFUQ01B82D6 unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggcccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15702 JY8QFUQ01AP05X productive Homsap IGHV3-7*01 F 1022 96.79 211/218 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [1.17.38.11] CSNGYGDFPRRW in-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cgtctggattcaccttcaggagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgacaaattctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +15703 JY8QFUQ01C4O02 unproductive Homsap IGHV3-48*02 F 991 94.98 208/219 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [2.17.38.11] CARPAGEGDPFL##YYSGLDVW out-of-frame + gcctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccttttttgccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15704 JY8QFUQ01CPEK6 No results +15705 JY8QFUQ01A3BPF unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 163 92.11 35/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found cctctggattcacctttaccaactatggcatgagctgg +15706 JY8QFUQ01BW2GU productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 748 82.65 181/219 nt 82.19 180/219 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [2.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15707 JY8QFUQ01AY8NK productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcatctttgatgattttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15708 JY8QFUQ01C2A3X productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15709 JY8QFUQ01B1DWD unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 945 93.09 202/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CARKGPQKRWLPTAM#DMDVW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggcccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +15710 JY8QFUQ01ANKGS No results +15711 JY8QFUQ01ALIBX No results +15712 JY8QFUQ01CVNSL productive Homsap IGHV4-61*02 F 817 85.59 190/222 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [2.17.38.11] CARCPNYNIGTRGFDYW in-frame - gtttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15713 JY8QFUQ01DETD7 unknown (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt 92.59 200/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggGggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagGaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggaacagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15714 JY8QFUQ01CPGZT productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15715 JY8QFUQ01CZKYX productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +15716 JY8QFUQ01DSZOW No results +15717 JY8QFUQ01CHR4R unknown (see comment) Homsap IGHV1-8*01 F 200 55.45 112/202 nt 8 8 X 8.8.X [0.17.34.X] null - No rearrangement found tggagacaccttcaccagttatgatatccactgggtgcgacaggcctctggacaagggcttgagtggatgggatggatgaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15718 JY8QFUQ01A3AS4 No results +15719 JY8QFUQ01AXYES productive Homsap IGHV3-48*02 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CARDVPGPNDNYFDYW in-frame + cctctggattcagcttcagagactatggcatggcctgggtccgccaggctccagggaaggggctggagtgggtctcatacattggtaggattattagtgacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagggacgacgacacggctgtctatttctgtgcgagagatgtcccgggccccaatgacaactactttgactactggggccagggaaccctgcttaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggctccagggcttcttccccca +15720 JY8QFUQ01BL2JT No results +15721 JY8QFUQ01AVU4K productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +15722 JY8QFUQ01BB01O productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1057 99.07 214/216 nt 98.61 213/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [2.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15723 JY8QFUQ01CJBN2 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 909 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 8 21 8.8.21 [1.17.38.11] CARVMREHYYGAGNYPWGGMEVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggGactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctggaaatgagtagcctgagagccgaggacgcggccgtctattactgtgcgagagtgatgagggaacattattatggagcggggaattatccctgggggggaatggaagtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15724 JY8QFUQ01DED91 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); ctccggattcacctttagtagttactggatgcactgggtccgccAaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15725 JY8QFUQ01B5PQ5 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [1.17.37.11] CANASPV*LE#YFYYYGMDVW out-of-frame + stop codons in FR3-IMGT, from codon 99 of V-REGION: 2 nucleotides (from position 199 in the user submitted sequence), (cause frameshift) tctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacggccgtatattactgtgcgaatgcctcccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +15726 JY8QFUQ01DBC1W productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaAaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15727 JY8QFUQ01A2LE9 unproductive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKARIYFYGSGVIP#FDYW out-of-frame + cctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcgggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15728 JY8QFUQ01BJOG2 No results +15729 JY8QFUQ01BSYZW productive (see comment) Homsap IGHV4-4*07 F 813 86.92 186/214 nt 85.51 183/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 210 to 210 in the user submitted sequence), (cause frameshift); ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgCaaaactctaactacaaTcccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtaCtttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15730 JY8QFUQ01AWCOE productive (see comment) Homsap IGHV4-59*03 F (see comment) 764 83.72 180/215 nt 82.79 178/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-22*01 F 2 8 7 12 8.7.12 [1.17.38.11] CARGDDSTGYGEYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaatggatactactgcagctggttccggcaggccccaggaaagggactggagtgggtcgggttTtatacattggagtgGggaaaaccgattacaatcctgccctcgagagtcgagtcagtctatccatggacacgtccaagagtcaagtctccctgaaggtgacctctgtgaccgctgcggacacggccgtctattactgcgcgagaggcgacgacagtactggttacggggaatattggggccagggaaggctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15731 JY8QFUQ01BTOR9 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*07 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [X.17.38.11] CTHLREEMSYEW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 95 of V-REGION: 'A' (1 nucleotides at position 190 to 190 in the user submitted sequence), (cause frameshift); tggagtcaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaAaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15732 JY8QFUQ01BPIPL No results +15733 JY8QFUQ01DUWI8 productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15734 JY8QFUQ01BW51W unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 95.19 198/208 nt 94.71 197/208 nt Homsap IGHJ4*03 F (see comment) 123 72.92 35/48 nt Homsap IGHD2-21*02 F 1 6 8 X 6.8.X [X.17.38.11] CARLCGNDCRNDDF*YL# out-of-frame - stop codons Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); caccttcagtacctactggatgcactgggtccgccaagttccagggaAaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgatttttgatatctgggggccaagggacattggtcaccgtctcttcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15735 JY8QFUQ01A312M productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15736 JY8QFUQ01AVHAL No results +15737 JY8QFUQ01CQQ2D productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + ctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15738 JY8QFUQ01CBL5V No results +15739 JY8QFUQ01CF885 productive (see comment) Homsap IGHV3-30*10 F (see comment) 706 81.02 175/216 nt 80.56 174/216 nt Homsap IGHJ1*01 F 152 76.92 40/52 nt Homsap IGHD1-1*01 F 1 8 8 16 8.8.16 [1.17.37.11] CSRGTTGTTDDSRLFQHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 157 in the user submitted sequence), (cause frameshift) ctctggattcagcttcggcaattacgccatgcactgggtccgccaggctccaggcaagggcctagagtgggtggctgtcataaataaggctgggaagactaaacattatatagactccgtgaagggccgattcaacgtctccagagacaactccgaaaaacactctatttggagatgaataacgtgggagttgaggacacggctgtatattattgttcgagaggtaccacggggacgacagacgactcgaggttgttccaacactggggccagggcgccctggtcaccgtttcgtcaacatccccgaccagcccccaaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttc +15740 JY8QFUQ01A17D9 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 912 92.06 197/214 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-16*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARHNYGNEKYIMDVW in-frame - tggatacaactttgccacctattggatcggctgggtgcgccacatgcccgggaaaggcctggaatggatggggatggtctttgctggtgactctgacaccagatacagtccgtccttccgaggccaggtcaccatgtcagccgacaagtccatcaacaccgcctacctgcagtggagcagcctgatggcctcggacaccgccatatattactgtgcgagacataattatggaaacgagaagtacattatggacgtctggggccaggggaccacggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15741 JY8QFUQ01A2MSQ productive (see comment) Homsap IGHV3-7*01 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'GT' (2 nucleotides at position 13 to 14 in the user submitted sequence), (cause frameshift); tctggattcaccGTtttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15742 JY8QFUQ01BXH98 productive (see comment) Homsap IGHV3-9*01 F (see comment) 786 83.86 187/223 nt 83.41 186/223 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [3.17.38.11] CGRIAKPGLGALDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); aggggcgttgggattcacAttttaatgaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctggggccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15743 JY8QFUQ01BQ2GI productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 789 84.55 186/220 nt 84.09 185/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctgtggactccatcagtagtactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15744 JY8QFUQ01BTX5G productive (see comment) Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 735 81.74 179/219 nt 81.28 178/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 3 10 6 15 10.6.15 [1.17.38.11] CARVWVAGSRDENFDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,74% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) tctcgggtgcttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtggggcacctattacaacccgtctctcaagagtcgacttgacctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcccggtcaccgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15745 JY8QFUQ01CDCBG productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15746 JY8QFUQ01BUYZM unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAGSGRDPYGINVW# out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctgggggccaaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15747 JY8QFUQ01C2JMT productive Homsap IGHV3-43*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-8*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDRIGSLYYFDHW in-frame - cgtcaggattcacatttgctgaatataccatgcactgggtccgtcaagttccggggaagggtccggagtgggtctctcttattagttgggatggtggcagcacatactatgcagactctgtgaagggccgattcaccatctccagagacaacagcaaggactccctgtatctgcaaatgaacagtctgagaactgaggacaccgccttgtattactgtgcaaaagataggattgggtccttgtactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15748 JY8QFUQ01AF4LW productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggGggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttcccccag +15749 JY8QFUQ01BM12K productive (see comment) Homsap IGHV2-5*02 F, or Homsap IGHV2-5*04 F 990 89.75 219/244 nt 89.34 218/244 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD2-2*01 F 2 10 7 13 10.7.13 [9.17.38.11] CARKYGSSTNGFDPW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'A' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcacgttctctggattctcactcaacacAcaggggaatgggcgtggactggatccgtcagcccccaggaaaggccctagagtggctaggcctcatttactgggatgatgatacgcgctacagcccatctctgaggaacaggctcagcatcaccaaggacacttccaaaaaccaggtggtcctgacactgaccaacgtggacgctatggacacaggcacatattattgtgcgcgcaaatatggcagcagtacgaacggattcgacccctggggccagggactcctggtcaccgtctctcagcatccccgaccagccccaaggtcttccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +15750 JY8QFUQ01ANBAE productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +15751 JY8QFUQ01BGCXQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 766 82.02 187/228 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [5.17.38.11] CARDDGGHMTLDVW in-frame - Low V-REGION identity (82,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtggccaatgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15752 JY8QFUQ01CUHEG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15753 JY8QFUQ01CG6E8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15754 JY8QFUQ01AFT0Y No results +15755 JY8QFUQ01CQS1T productive Homsap IGHV3-11*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame - ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggctttcatacattagtggtagtggaactaccatatcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaggaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgaggcgggtgtggggatatagttatggttccgtttcgtactactttgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15756 JY8QFUQ01B2OMV unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*03 F or Homsap IGHV3-48*04 F (see comment) 328 64.8 116/179 nt 8 8 X 8.8.X [1.17.25.X] null - No rearrangement found Low V-REGION identity (64,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcactagaagtcccatgaattgggtccgccaggctccggggaaggggctggaatgggttgcatacattagtagtgatggtagtaccctatactacgcagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15757 JY8QFUQ01ADA8M No results +15758 JY8QFUQ01DJ645 unproductive (see comment) Homsap IGHV3-9*01 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - stop codons in CDR1-IMGT at codon 37 of V-REGION: 'GT' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift); ctctggattcacctttcatgattaGTagccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15759 JY8QFUQ01B7SJP No results +15760 JY8QFUQ01B5OYN unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 1 8 8 18 8.8.18 [1.17.38.11] CARGEFLL*N*WSKGFLDYW in-frame + stop codons cctctggattcaccttcactacctcctggatgcactgggtccgccaagctccagggaaggggctaatgtgggtcgcacgtattaataaggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaccacactgtacttggaaatggacagtctgagagtcgaggacacggctatgtattattgtgcaagaggggaatttttactatgaaactagtggtcgaaggggtttttggactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15761 JY8QFUQ01CZT8X unknown (see comment) Homsap IGHV4-4*07 F 809 86.51 186/215 nt 86.05 185/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggtacctccatcagcacttactattggagttgattccggcagcccgccgagaaggGgactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccgaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactca +15762 JY8QFUQ01DNEFC unproductive Homsap IGHV3-33*03 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 X 8.7.X [1.17.38.11] CARDWGSSGWFGRC#DVW out-of-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift) cgtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagattgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15763 JY8QFUQ01B7XS9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGHSYYVSSGPDYW in-frame + cctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtagtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15764 JY8QFUQ01BW0AQ productive (see comment) Homsap IGHV3-48*02 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [2.17.38.11] CARGQKWLQVLRWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'A' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcgacagatacagtatgaactAgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15765 JY8QFUQ01AJ58T unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 881 90.23 194/215 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - caggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaagtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15766 JY8QFUQ01CHQBV productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 820 86.3 189/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAKVGNLYFFEYW in-frame - gcctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15767 JY8QFUQ01CELW1 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 709 81.69 174/213 nt 81.22 173/213 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.37.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 130 in the user submitted sequence), (cause frameshift) ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +15768 JY8QFUQ01DSB95 No results +15769 JY8QFUQ01BWZ3O unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDLYGADDL## out-of-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggtccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15770 JY8QFUQ01CIYFN No results +15771 JY8QFUQ01B08HB No results +15772 JY8QFUQ01BYREX No results +15773 JY8QFUQ01C2ROO productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctcgacacgcaccccccaagatgggaacgtggtcgtcgcagtgcctggtccccagggctcttcccccagga +15774 JY8QFUQ01BEX6B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [0.17.38.11] CAKVVWSLWYFDLW in-frame - ctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctagtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15775 JY8QFUQ01AJ8J4 No results +15776 JY8QFUQ01B6WCT productive (see comment) Homsap IGHV4-61*02 F 875 88.69 196/221 nt 87.78 194/221 nt Homsap IGHJ4*01 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-22*01 F 3 10 7 11 10.7.11 [1.17.38.11] CARAREFLTFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaacaatgatActtttctactggaactggatccggcaggccgccgggaagggactgcagtggattgggcgtatgtatgccagtgggaccactaactacaaccCcctccctcaagagtcgagtcaccatgtcagtagtcacgtcaaagaatcaattttccctgaagttgagttctgtgaccgccgcagacacggccatttactactgtgcgagggcccgagagtttctcacctttgactcctggggccaaggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15777 JY8QFUQ01AHQEV unproductive Homsap IGHV3-48*03 F 923 91.74 200/218 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD1-7*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDCDSGECNFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15778 JY8QFUQ01AG53L productive (see comment) Homsap IGHV4-61*02 F 834 86.82 191/220 nt 85.91 189/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 10 7 15 10.7.15 [1.17.37.11] CARDTGQTYGRGPLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 217 in the user submitted sequence), (cause frameshift) tctctggtgcctccataaataggggtaattattactGggaactggatccggcagcccgccgggaagggcctggaatggattggccgaatctatacaagtgggagcaccatctacaacccctccctcgggggtcgagtcaccatgactgtagacccgtccgagaatcagttcttcctgagactgagttctgtgaccgccgcagacacggccgtttattttgtgcgagagacactggacaaacctacggtcggggccctttggactactggggccagggaatcctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15779 JY8QFUQ01AMHRT unknown (see comment) Homsap IGHV2-5*03 F 177 54.69 105/192 nt 10 7 X 10.7.X [9.17.25.X] null + No rearrangement found gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +15780 JY8QFUQ01AFICH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1005 95.45 210/220 nt 94.55 208/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); ggcctctggattcagcttGcaatagttactggatgcactgggtccgccaagctccagGggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15781 JY8QFUQ01ALMSJ productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 971 92.86 208/224 nt 92.41 207/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 7 7 8 7.7.8 [5.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) gcctctgcagcctctggattcattgtcaatagcactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15782 JY8QFUQ01CEN0W unproductive Homsap IGHV3-30*01 F 869 88.99 194/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGSHQSE#YGLDVW out-of-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcgggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15783 JY8QFUQ01CG8U2 productive (see comment) Homsap IGHV3-66*02 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 7 13 8.7.13 [1.17.38.11] CASVGVGATVAFQYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); cctctggattcaccgtcagtgatagttacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcgattatttataGggggaggtaccacatattatgccgactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctatatcttcaaatgaacaccctgagaggtgaggacacggctctatattactgtgcgagcgtcggagtgggagctacagtcgcctttcaatactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcctgcctggtccagggcttcttcccccaa +15784 JY8QFUQ01BI18V productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtccgtgggaactcag +15785 JY8QFUQ01CHGC7 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 912 89.69 200/223 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD2-2*01 F 2 8 8 18 8.8.18 [3.17.38.11] CARYCSSDSCQGYHDAFDVW in-frame - taaggcttctggatacatcttcacgaaccactggatcggctgggtgcgccagatgccgggtagaggcctggagtggatggggatcatctatcctggtgactccgattccagatacggcccgtccgcccaaggccaggtcaccttctcagtcgacaagtccatcgccaccgcctaccttcagtggagtagcctgaaggcctcggacaccgccacgtactactgcgcgagatattgtagtagtgacagctgccaagggtaccatgatgcttttgatgtctggggccaagggacaatggtctccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15786 JY8QFUQ01DMFVC unknown (see comment) Homsap IGHV4-4*07 F 890 90.7 195/215 nt 89.3 192/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in CDR1-IMGT at codon 36 of V-REGION: 'TGATTC' (6 nucleotides at position 23 to 28 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagTGATTCtcactactggagttggatccggcagcccgccggGgaagggactggagtggattgggcgtgtctacgccagtgGggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttcggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtgctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagaacacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc +15787 JY8QFUQ01DPWGM productive (see comment) Homsap IGHV3-72*01 F 953 91.96 206/224 nt 91.07 204/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'AG' (2 nucleotides at position 54 to 55 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'T' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); cctctggattcaccttaagtgatcactacatggactgggtccgccaggctccaAGggaagggggctggagtTgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctgcgctctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15788 JY8QFUQ01BAFLC productive Homsap IGHV3-7*01 F 887 89.45 195/218 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15789 JY8QFUQ01DHSUC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGHSYYVSSGPDYW in-frame - ctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggctt +15790 JY8QFUQ01C6XVX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15791 JY8QFUQ01B5NWN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKGIVGASMQADWFHPW in-frame - cctctggattcgtctttggcgactatgcgatgagctgggtccggcaggctccagggagggggctggagtgggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15792 JY8QFUQ01AGEU2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CVRGDYGGAPRTLLRP#YGLDVW out-of-frame + cctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagtcgaggacacggctatgtattattgtgtgagaggggactacggtggcgccccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15793 JY8QFUQ01CMN9M unproductive Homsap IGHV3-9*01 F 963 93.55 203/217 nt Homsap IGHJ2*01 F (see comment) 94 64.15 34/53 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDAMGGAGDWAAFG#LG out-of-frame + Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) ctctggcttcatctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagcgctaccatagaatatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctggaaatcaacagtctgagacctgaagacacggccttatactactgcgcaaaagatgcgatgggaggagctggtgattgggctgcttttggtatctggggcccagggggacaatggtcactgtctcttcaggcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15794 JY8QFUQ01CNCFI unknown (see comment) Homsap IGHV3-7*01 F 1031 96.79 211/218 nt 96.33 210/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15795 JY8QFUQ01C95SC productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15796 JY8QFUQ01C65EF No results +15797 JY8QFUQ01BCK6X productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 942 94.31 199/211 nt 92.89 196/211 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [0.16.37.11] CARDGGHSYGPSFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 120 in the user submitted sequence), (cause frameshift) tggatacaccttcaccaggtacattatgcactgggtgcgacaggccctggacaaggcttgagtggatgggaataatcaaccctagaggtgttagcagaagctacgcacagaagttccaggcagagtcaccatgaccaccgacacgtccacgagcacagtctatatggagctaaacagcctgagatctgaggacacggccgtttattactgtgcgagagatggagggcacagctatggaccctcctttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15798 JY8QFUQ01CHME0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15799 JY8QFUQ01AXA7J productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +15800 JY8QFUQ01CERKI unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1004 95.87 209/218 nt 95.41 208/218 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CARPGGDCLL*WW*LLR#PG out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); cctctggattcagcttcaatagttGactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccagggggggattgcctattgtagtggtggtagctgctacgacccctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15801 JY8QFUQ01CHW93 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15802 JY8QFUQ01ABNQY unproductive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGSHQSE#YGLDVW out-of-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcgggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15803 JY8QFUQ01BTJ3Q unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt 97.33 219/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 X 10.9.X [1.17.38.11] CTRGSSRGGDMMRTTMS#DFW out-of-frame + in FR3-IMGT at codon 74 of V-REGION: 'T' (1 nucleotides at position 134 to 134 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaaTgtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcgggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccg +15804 JY8QFUQ01A9XZY productive (see comment) Homsap IGHV3-7*01 F 955 93.15 204/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARTSSREITDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'AC' (2 nucleotides at position 53 to 54 in the user submitted sequence), (cause frameshift); gcctctggaGttcacctttagtggctattggatgagttgggtccgccaggctACccggggaagggtctggagtgggtggccaacatagagaaagatggaagtgacataaagtatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtctctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +15805 JY8QFUQ01CLGDD productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [2.17.38.11] CARDPSGSGWAFESW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); gcgtctggatTtccctttcagtagagatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatggtatggtatgatggaagtaatacacaccatgcagattccgtgaagggccgattcatcatttccagagacaattccaagaataaagtgtatctgcaaatgaacagtctgagagacgaggacacggctgtctattattgtgcgagagatccgagcggcagtggctgggcctttgagtcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15806 JY8QFUQ01BWJEK unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt 90.78 197/217 nt 8 8 X 8.8.X [2.16.38.X] null - No rearrangement found in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctctagggaagggctggagtggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagaggatcggtgacttgggcgggctggttcgaccccctgggggccaggggaacccgtggtcaccgtctcctcagcctccaccaagggcccatcggtnttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15807 JY8QFUQ01BHQ6M productive Homsap IGHV3-7*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRDRFYDSSGYEFGELGDYSDHW in-frame + ctctggattcacatttagtaactactggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctgtgtgagagatcgattttatgatagtagtggttatgagtttggggaattgggggactactctgaccactggggccagggaacccaggtgcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +15808 JY8QFUQ01B02FB productive Homsap IGHV3-48*01 F 865 88.58 194/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [2.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + gtctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15809 JY8QFUQ01DB3OE productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame - cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15810 JY8QFUQ01A24GB unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDNYGDYW# out-of-frame + ctctgaaatcaccttcagcgaccactacatgagctggatccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15811 JY8QFUQ01BQMY8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1031 97.25 212/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARPGGIAYCSGGSCYDPW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15812 JY8QFUQ01AWSL1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVKGWNYHSATFGFDYW in-frame - ctctggattcacctttagtgactatgccataagctgggtccgccaggctccaggaaaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccattttcagagacaactccaaagacacgctgtatctgcaaatgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaacctttgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15813 JY8QFUQ01DG1D0 productive Homsap IGHV4-61*02 F 852 87.73 193/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 11 10.7.11 [1.17.38.11] CARSGWDNQFDFW in-frame + ctctggtgtcgccaccagtagtggcacttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaacccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15814 JY8QFUQ01AA37K productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 858 89.25 191/214 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame - ctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15815 JY8QFUQ01CSDHI productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame + ctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15816 JY8QFUQ01DXGBB unproductive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1025 95.54 214/224 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD4-11*01 ORF 2 8 10 X 8.10.X [1.17.38.11] CARHEGTPVSDVGGYGMDVW# out-of-frame + cctctggattcaccttcagtggctctgctatgcactgggtccgccaggcttccgggaaagggctggaatgggttggccgtattagaagcagagcttacagttccgcgacagcatatgcagcgtcggtgaaaggcaggttcaccatttccagagatgattcaaagaacacggtgtatctgcaaatgaacagtttgaaaaccgaggacacggccgtgtattactgtgctagacatgaagggactccagtaagtgatgtaggtggatacggcatggacgtctgggggccaaagggtccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +15817 JY8QFUQ01BAWV8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15818 JY8QFUQ01APXX1 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1085 100.0 218/218 nt 98.62 215/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'CA' (2 nucleotides at position 83 to 84 in the user submitted sequence), (cause frameshift); cctctggattcaGccttcagtagctatagcatgaactgggtccgccaggctccagggaagGgggctggagtgggtctcatccCAattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15819 JY8QFUQ01AN89A unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaagccttggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcg +15820 JY8QFUQ01C6WFJ No results +15821 JY8QFUQ01BOLEF productive (see comment) Homsap IGHV3-48*01 F 1095 100.0 220/220 nt 99.55 219/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.17.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtagctatagcatgaactgggtccGgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15822 JY8QFUQ01BR20I unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt 84.79 184/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD4-11*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CVRDSGPVRLR*VRV#MDVW out-of-frame + stop codons Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); ctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggcgtggaaGgtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaGggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggccccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15823 JY8QFUQ01CQO4K No results +15824 JY8QFUQ01AVD8T unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CANELGYCSGG# out-of-frame - cctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggcagcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15825 JY8QFUQ01AHVR6 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 267 62.42 103/165 nt 8 10 X 8.10.X [1.17.20.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (10 AA in JY8QFUQ01AHVR6 ; 8 AA in Homsap_IGHV3-7*01), and low V-REGION identity (62,42% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcactttcactaacgcctggatgagctgggtccgccaggctccagggaaggggctggagtggattggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15826 JY8QFUQ01CCJDP productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15827 JY8QFUQ01BSK8W productive (see comment) Homsap IGHV3-72*01 F 921 90.58 202/223 nt 90.13 201/223 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD2-8*02 F 2 8 10 17 8.10.17 [1.17.38.11] CTRDTTDTGGQSFNGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggtttccCccttcagtgaccacttcatggactgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtttggggccaggggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15828 JY8QFUQ01BU2CX unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDRNNYYSDY## out-of-frame + gtctggattcaacttcggaagttatggcatgcgctgggcccgccaggctccaggcaaggggctggagtgggtggcatttatttggtatgacggaagaaataaatattatgcagactccgttaagggccgattcaccatctccagagacaattccgagagcacactggatctgcaaatgaatagcctgagagccgaagacacggctgtctattactgtgcgagggataggaataattactactccgactactggggccaggggaaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +15829 JY8QFUQ01A5V7V productive Homsap IGHV4-61*02 F 916 92.49 197/213 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD6-13*01 F 2 9 7 19 9.7.19 [X.17.38.11] CAREAPKAAANSYNSYVMDVW in-frame + ggctccatcagtagtggtagttactactggagctggacccggcagcccgccgggaggggcctggagtggattgggcgtgtccataacagtggtagttccaattacaagccctccctcacgagtcgagtcaccatattagtagacacgtccaagaatcagttctccctgaagctgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagagaagcgcccaaggcagcagctaattcctacaactcttacgttatggacgtctggggccaagggaccacggtcaccgtcttctcagcatccccgaccagccccaaggttcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +15830 JY8QFUQ01DH57H productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15831 JY8QFUQ01CH326 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1056 99.53 213/214 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [0.17.38.11] CARLHGYCGGGYCYDWYFDLW in-frame + tggatacagctttaccagctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgattccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgagactccatgggtattgtggtggtggttattgctacgactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +15832 JY8QFUQ01CKANK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15833 JY8QFUQ01DE136 No results +15834 JY8QFUQ01BI5WK unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 912 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) ctctgggattcacctttagcagccntcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15835 JY8QFUQ01CW2RH No results +15836 JY8QFUQ01DG254 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtGacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15837 JY8QFUQ01AFE6Z unproductive (see comment) Homsap IGHV3-38*01 ORF, or Homsap IGHV3-66*02 F (see comment) 732 82.71 177/214 nt 81.31 174/214 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-21*01 F 3 8 6 11 8.6.11 [2.17.38.11] CARHLMVYALDVW in-frame - stop codons Low V-REGION identity (82,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'TCT' (3 nucleotides at position 82 to 84 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 71 of V-REGION: 'G' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift); agtctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaGggggctggagtgggtctcagTCTtatttagtactggcactgcatactacgcagactccGtgaaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15838 JY8QFUQ01ADT3T No results +15839 JY8QFUQ01AJIO8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [2.17.38.11] CVRRGMVAGRYDAFDIW in-frame - gcctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15840 JY8QFUQ01BBX5W No results +15841 JY8QFUQ01BRYZ3 productive (see comment) Homsap IGHV3-48*02 F 949 93.52 202/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [1.16.38.11] CARDMIIFGGALDNW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) ctctggattcgccttcagtagttccagcatgaactggtccgccagggtccagggaaggggctggagtggatttcacacattaGggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggagcccttgacaactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15842 JY8QFUQ01AP3M5 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15843 JY8QFUQ01B71ED productive Homsap IGHV3-9*01 F 802 85.39 187/219 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-9*01 F 2 8 8 16 8.8.16 [2.17.38.11] CVKDLSGRPKDMHGMDVW in-frame - Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) gcctctgggttcagttttagcaattatgccatgcactgggtccgtcaagctccagggaagggcctgcaatgggtctcacgtattaattggaacagtggaaacatagcctatgcggcctctgtgaggggccgattcaccgtctccagagacgacgccgagcactccctgtatttacaaatgaatggtctgacaactgaagacacggccttatactattgtgtgaaagatttgtctggccgaccaaaggacatgcacggcatggacgtctggggccaagggaccacggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15844 JY8QFUQ01CDZI0 No results +15845 JY8QFUQ01DVPUO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKVLSGDFQRIMIRPFFDHW in-frame - gctctggattcacatttaacaactatgccatgatttgggtccgtcagggtccagggcgggggctggagtgggtctcagcaatcagtggttatggtggtaccacctacgccgcaaagtccgtggagggccggttcgacatttccagagacaactccaagaacacggtgtatctgcaaatgaacggcctgagggccgaggacacggccgtatattactgtgcgaaggtgttgtcgggagactttcaacggattatgataagaccgttctttgaccactggggccagggaacccagctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +15846 JY8QFUQ01BZ9AE No results +15847 JY8QFUQ01APYBC productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 923 91.74 200/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); cctctggattcaTcgttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaataCcgggggggactgacacagcctatgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15848 JY8QFUQ01A3EA4 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15849 JY8QFUQ01C48PF No results +15850 JY8QFUQ01BR6QV productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.16.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gcctctacattcacgGtttagtcggtattggatgagctggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttcttcgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15851 JY8QFUQ01CU8CL productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 973 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaTggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15852 JY8QFUQ01BEK4N productive Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15853 JY8QFUQ01CGQES productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 18 8.8.18 [1.17.38.11] CVRESGDYGGKYSKSYFDYW in-frame + cctctggattcactttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatcaattactagaagttctagttatatgtcctacgcagactcagtgaagggccgattcaccatctccagagacaatgccgagaattcactgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgtgagagaatcgggtgactacggtggtaaatatagcaagtcatactttgactattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15854 JY8QFUQ01BGLRM No results +15855 JY8QFUQ01A0GZB No results +15856 JY8QFUQ01CKWBK productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 932 92.2 201/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15857 JY8QFUQ01BB0A4 unproductive Homsap IGHV3-11*01 F 976 94.91 205/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD7-27*01 F 2 8 8 X 8.8.X [1.16.38.11] CARDLNG#DYW out-of-frame - in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) cctctgaatccaccttcagtgactactacatgaactggtccgccaggctccagggaagggctggagtgggtttcatatattagtagtagtagtagtatcataacctacgcagactctgtgaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgagagatcttaacggggggactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15858 JY8QFUQ01BP3BX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 2 8 8 18 8.8.18 [1.17.38.11] CSRHGGYTKLYNQNVYLDYW in-frame + tctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcaccacctccagagacaactctagaaactcgctgtgtctgcaaatggacagcctgagagccgaggacacggctgtgtattactgttcgagacatggaggttacacgaaactctacaatcaaaatgtctaccttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctgtccagggcttgttcccc +15859 JY8QFUQ01C7G6G No results +15860 JY8QFUQ01C66GX productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame - tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaagactacttccccgaaccggtgacggtgtcgtggaactcag +15861 JY8QFUQ01BDX24 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 854 88.84 191/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 2 8 7 19 8.7.19 [1.17.38.11] CARSSDYLWGSYRYPYYFDYW in-frame - tctctggtgactccatcagtagttacttctggagttggatccggcagcccccagggaagggactggagtggattggatatgtctattacagtggaagtaccaagtataatccttccctcgaaagtcgagtcaccatatcattagacacgcccaacaaccagttctccctgagcctgacctatgtcaccgctgcggacacggccatatactactgtgcgagaagctctgattacctttgggggagttatcgttatccctactacttcgactactggagccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15862 JY8QFUQ01CW1BP productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctactggagctggatccggcagcCccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcg +15863 JY8QFUQ01CDZHK unproductive Homsap IGHV3-33*03 F 932 92.2 201/218 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDGEQWLVWTL#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cgtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15864 JY8QFUQ01BRMK5 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 2 8 8 X 8.8.X [1.17.38.11] CARKRVPGGTFM#DYW out-of-frame - cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggacttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15865 JY8QFUQ01ARH9K productive Homsap IGHV3-30*01 F 878 89.45 195/218 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [1.17.38.11] CACGHMRDGYDVW in-frame - cctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15866 JY8QFUQ01DO7XU unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 914 90.87 199/219 nt 90.41 198/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); gcctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtGgggtgtcacgtantaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15867 JY8QFUQ01CD6FW No results +15868 JY8QFUQ01AHX53 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15869 JY8QFUQ01DCQQ3 productive Homsap IGHV3-30*01 F 996 95.0 209/220 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [2.17.38.11] CAKDELPWDTIEYYFDYW in-frame - ggcctctggattcaccttcaatacctattctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15870 JY8QFUQ01CJHJS productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1105 100.0 222/222 nt 99.55 221/222 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [2.17.38.11] CARSRTFYGSANYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'T' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccaTgggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15871 JY8QFUQ01C3DAG productive Homsap IGHV3-7*01 F (see comment) 733 82.41 178/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +15872 JY8QFUQ01AD2NS productive (see comment) Homsap IGHV3-9*02 F (see comment) 733 82.41 178/216 nt 81.94 177/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-9*01 F 2 8 7 19 8.7.19 [1.17.38.11] CVKDKDKVGGHTGHYPTFDFW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 97 in the user submitted sequence), (cause frameshift) ctctggattcaaccccgaaaactttgccatgcactgggtccgacaagttccagggaagggcctgaagtgggtctcaggtataaattggaatggacgaaaacaggatatgcggagtctgtgaggggccggttcaccatctccagagacaatgacaagaacgtcctttctttgcaaatgaccaatttggggactgaggacacggccttctatttttgtgtgaaagataaggacaaagtggggggccacactggccattatcccacgtttgacttctggggccagggagccctggttaccgtcgcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15873 JY8QFUQ01CQJR7 productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + ctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15874 JY8QFUQ01CSACT No results +15875 JY8QFUQ01BNRL4 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 1 8 7 17 8.7.17 [1.17.38.11] CARVVMATVYTGSYYFDDW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); tgtatggtgggtccttcagtgataactcctggacctggatccgccagcccccagggaaggggctggagtggattggagagatcaatcatagtggaaAacaccaactacaacccgtccctcaggagtcgagtaatcatgtcaatagacacgtccatgaaccaattctccctgaagctgacttctgtgaccgccgcggacacggctgtgtattattgtgcgagagtcgtgatggctacagtttatactgggtcctactactttgacgactggggccagggaaccctggtctccgtcttctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15876 JY8QFUQ01C41FF productive Homsap IGHV3-33*03 F 968 94.04 205/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-22*01 F 2 8 8 20 8.8.20 [1.17.38.11] CARDGDYYDSSGNFLGHSFDIW in-frame + cgtctggattcagcttcagtagttatggcgtgaactgggtccgccaggctccaggcaaggggctggagtgggtggctgttatttggtatgacggcaataataaatattatgcagactccgtgaagggccgattcaccatctccagagacgactccaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcgagagatggagattattatgatagtagtggtaatttcctgggacattcttttgatatctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15877 JY8QFUQ01A3I7J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 8 8 10 8.8.10 [1.17.38.11] CATWIQSHFDYW in-frame + ctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagccattaatcaagatgccattaccacacactacccagactccgtgaagggccgcttcaccgtctccagagacaattccaagaacacactctatctgcaaatgagcagcctgagagccgacgacacggccgtatattattgtgcgacgtggatacagtctcactttgactattggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15878 JY8QFUQ01C7KSE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAIEHTLPSGQGLGIEYFW in-frame - cctctggattcaactttaacagctttgccatgagctgggtccgccaggttccagggatggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactccgtgaagggccggttcaccatctccagagacaactccaacaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgatcgagcatacccttccgtccggacagggattagggattgaatatttctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15879 JY8QFUQ01CLP4K productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15880 JY8QFUQ01C1P51 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P 101 53.08 69/130 nt 8 7 X 8.7.X [X.17.11.X] null - No rearrangement found stop codons ggattcatcttcagtgactactacatgacctggatccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15881 JY8QFUQ01DGR27 productive (see comment) Homsap IGHV3-7*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [2.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) gcctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15882 JY8QFUQ01BAJEK No results +15883 JY8QFUQ01AVJ1Q productive (see comment) Homsap IGHV4-39*03 F 929 91.36 201/220 nt 90.91 200/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcCccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15884 JY8QFUQ01B5TTZ productive (see comment) Homsap IGHV3-7*01 F 932 92.2 201/218 nt 91.28 199/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 142 76.0 38/50 nt Homsap IGHD1-26*01 F 3 8 8 8 8.8.8 [1.17.38.11] CVRERGGRYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'TAA' (3 nucleotides at position 21 to 23 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'GAC' (3 nucleotides at position 36 to 38 in the user submitted sequence), (do not cause frameshift); cctctggattcacctttaatTAAcacatttggataGACattggggtccgccaggctccagggaaggggctggagttggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtatctgcaaatgagcagcctgagagccgaggacacggctatgtattattgtgtgagagagagaggggggaggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15885 JY8QFUQ01B4ZHH productive (see comment) Homsap IGHV3-30*01 F 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [2.17.37.11] CARGTMLRGVTKARYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 211 in the user submitted sequence), (cause frameshift) agcctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15886 JY8QFUQ01DKV8D productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + cctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15887 JY8QFUQ01B6ORR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 888 89.55 197/220 nt 89.09 196/220 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); aggctctgacttGcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15888 JY8QFUQ01BZ10X productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 923 91.74 200/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 205 to 205 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) gcctctggattcaccCtttggttattatggcatgactgggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacgGgccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15889 JY8QFUQ01CKE7Y productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15890 JY8QFUQ01AKAYX unproductive (see comment) Homsap IGHV3-11*01 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDRGEKWELR##DHW out-of-frame - stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctgggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggGggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccagggtcaacgccaagaactcactgtctctgtaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgaaagatcggggggaaaagtgggagctacggacttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15891 JY8QFUQ01C8J7S No results +15892 JY8QFUQ01CNEV5 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 869 88.99 194/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ggcctcctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15893 JY8QFUQ01CQV6R unproductive Homsap IGHV3-74*03 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRDSDSSASYFA#W out-of-frame + cctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15894 JY8QFUQ01BAD49 unproductive Homsap IGHV4-39*02 F 938 91.86 203/221 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-9*01 F 2 10 7 X 10.7.X [1.17.38.11] CARLLRVYDWYSQRGLL#DTW out-of-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctccgatggctccatcagcactagtaattactactggggctgggtccgccagcccccagggaaggggctggagtggattggaagtatatattatagtgggagcaccgactacagctcgtccctcaggagtcgcgtcaccatatccagagacacgtccaagaaccacttctccctgaaggtgacctctgtgaccgccgcagacacggctatatattactgtgcgagactcttacgggtttatgactggtacagtcaaagggggttacttcgacacctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgggtgtcgtggaactc +15895 JY8QFUQ01AZ65I productive Homsap IGHV3-9*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSGGYTHNYFDYW in-frame + ctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagctggaatagtggtagtatagggtatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattactgtgcaaaaggggatagtggtggttatacccacaactactttgactactggggccagggaaccctggtcaccgtctcctcagcatcctcgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15896 JY8QFUQ01B3FLS unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 189 60.0 81/135 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +15897 JY8QFUQ01ANTXC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKLGVAATTWNFFDYW in-frame + cctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15898 JY8QFUQ01ACXOG productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 843 87.27 192/220 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ggcctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +15899 JY8QFUQ01B3YVR productive (see comment) Homsap IGHV4-4*07 F, or Homsap IGHV4-61*02 F 957 94.39 202/214 nt 92.99 199/214 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 8 7 11 8.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'CAGTAC' (6 nucleotides at position 19 to 24 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); ctctggtgggtccatcagCAGTACtagttactactggagctggatccggcagcccgccgggaagggactggagtggatgggggCgtatctataccagtgggatcaccaactacaaccCcctccctcaagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgntccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +15900 JY8QFUQ01CQ04Z productive Homsap IGHV3-7*03 F (see comment) 766 83.56 183/219 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [2.17.38.11] CTRRGFMDVW in-frame - Low V-REGION identity (83,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattgcaatttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15901 JY8QFUQ01CDOX5 productive Homsap IGHV4-61*02 F 1010 95.48 211/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*02 F 2 10 7 15 10.7.15 [1.17.38.11] CARAGKQDFWSGYSDDW in-frame + tctctggtggctccatcggcagtggtagttattactggagctggatccggcagcccgccgggaagggactggaataccttgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgctgacacggccatttattactgtgcgagagcggggaaacaggatttttggagtggttattctgacgactggggccagggaaccctggtcatagtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15902 JY8QFUQ01DPNH7 productive (see comment) Homsap IGHV3-72*01 F 952 92.34 205/222 nt 91.89 204/222 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 10 14 8.10.14 [1.16.38.11] CARLHYSGGWYGLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgaccactacatagactgggtccgccaggctccaggaaaggggctggagtggttggccgtactcgaaataaagctaacggttacagtacagagtatgccgcgtctgtgaaaggcagattcaccgtctcaagagatgactcagagaacttagtgcatctgcaaatgaacagcctgaaaagcgaggacacggccctgtattactgtgctagactgcactacagtggtggctggtacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15903 JY8QFUQ01DDH3H No results +15904 JY8QFUQ01DCRDZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKLGVAATTWNFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift); ctctacattcgcctttagcaactatgccatgaGgctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15905 JY8QFUQ01BW1MW productive Homsap IGHV3-11*01 F 883 89.5 196/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARDDSCSGGSCYEYW in-frame - acctctggattcagtttcagtgactactacatgagttggatccgccaggctccagggagggggctggagtgggtttcatatattgatagcggtggtaccgccatgtactactcagactccgtgaagggccgattcaccatctccagggacaacgccaagaagtcactgtttctgcaaatgagtagcctgagagccgaagacacggccgtgtactattgtgcgagagatgactcttgtagtggtggtagctgttacgaatactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15906 JY8QFUQ01CP7TZ No results +15907 JY8QFUQ01DIB2J No results +15908 JY8QFUQ01CN554 productive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 965 93.21 206/221 nt 92.76 205/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARDRGPSSSSKMEYDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); tctctggtgcctccgtcagcagtggtAgttttctactggacctggattcgtcagcacccagggaagggcctggagtggattgggtacatctattacagtgggagcgcctactacaacccgtccctcaagagtcgagttgccatatcaatagacacgtctaagaaccagttctccctgaacttgagttctgtgactgtcgcggacacggccgtttattactgtgcgagagatcggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +15909 JY8QFUQ01BBY5Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKRLEGVADDAFDIW in-frame + cctctggattcacgtttagtagctatggcatgggctgggtccgtcagactccagggaaggggctggagtgggtctcaactattagtggcagtggtcggagcacatactacgctgactccgtgaagggccggtacaccatctccagagacaactccaagaacacggtgtctgtgcaaatgaacagcctgagagtcgaggacacggccgtttattattgtgtgaaaaggttggagggagtggctgatgatgcttttgatatctggggcccagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +15910 JY8QFUQ01ATJH3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 97 of V-REGION: 'G' (1 nucleotides at position 194 to 194 in the user submitted sequence), (cause frameshift); ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccGgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15911 JY8QFUQ01CRQE6 unknown (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 815 86.24 188/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaacatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15912 JY8QFUQ01CAQ16 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSGPSGYARYESMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15913 JY8QFUQ01CTYEK unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKK*GVGDG##WYFDFW out-of-frame + stop codons in CDR2-IMGT at codon 58 of V-REGION: 'ATG' (3 nucleotides at position 88 to 90 in the user submitted sequence), (do not cause frameshift); cctctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattactaATGgtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttatttctgtgcgaaaaaatagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15914 JY8QFUQ01AKBD8 No results +15915 JY8QFUQ01AMBZM No results +15916 JY8QFUQ01BALS7 No results +15917 JY8QFUQ01B4U42 No results +15918 JY8QFUQ01CW89R productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 781 83.78 186/222 nt 82.88 184/222 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [3.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); caatgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15919 JY8QFUQ01ANMB1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 926 92.56 199/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 7 8 13 7.8.13 [2.16.38.11] CAKRRGGYYIDFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'AG' (2 nucleotides at position 122 to 123 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 3 nucleotides (from position 21 in the user submitted sequence), (do not cause frameshift)in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 63 in the user submitted sequence), (cause frameshift) gccactggattcacccttaactatgccataaattgggtccgccaggctccagggaaggggctgagtgggtctcaactatcaatactagtggtagtagcacatactacgcagactccgtgaaAGgggccggttcaccatctccagagacaattccaagaacgaggtgtatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaagcggaggggtggttattacatcgactttgactactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15920 JY8QFUQ01CB9CI productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 990 95.39 207/217 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARGDGSGWSGVDVW in-frame - ctctggattcacctttgatgatcatggcatgagctgggtccgccaagctccagggaaggggctggagtgggtctctggtatttattgggatggtggtaatacaggttatgcaggctctgtgaagggccgattcaccatctccagagacaacgccaagaacttcgtgtatctgcaaatgaacagtctgagagccgaggacacggccttgtattattgtgcgagaggtgatggcagtggctggtccggtgtggacgtctggggccaagggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15921 JY8QFUQ01BJ694 unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 138 64.1 50/78 nt 8 X X 8.X.X [1.16.X.X] null + No rearrangement found ctctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +15922 JY8QFUQ01CZKYQ No results +15923 JY8QFUQ01CVP6L productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 728 82.33 177/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDWGGSFDRYYFDYW in-frame - Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15924 JY8QFUQ01BGN7G unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 89 58.57 41/70 nt 8 X X 8.X.X [1.14.X.X] null + No rearrangement found ctctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttcccc +15925 JY8QFUQ01CS8OP productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15926 JY8QFUQ01CT923 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 914 91.28 199/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + cctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggcgtggagtgggtctgctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15927 JY8QFUQ01AQQ5Z productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVKGWNYHSATFGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtgactatgccataagctgggtccgccaggctccaggaaAaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccattttcagagacaactccaaagacacgctgtatctgcaaatgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaacctttgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15928 JY8QFUQ01C5JDI No results +15929 JY8QFUQ01AWP5Q No results +15930 JY8QFUQ01CJ536 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15931 JY8QFUQ01B6JOD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 847 87.67 192/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [2.17.38.11] CTREVGATDYW in-frame - ctccggagttcaacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15932 JY8QFUQ01AOMNK productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15933 JY8QFUQ01BFYFA productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKAYDDVLTSYYIAAFIDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgccatgcattgggtccgccaggctccaggcaaggggccggagtgggtggcagttatatcatatgatggaagtcataaagactatgcagcctccgtgaagggccgattcaccatctccagagacaattccaagagtacgttgtatctgcaaatgaacagcctgagacctgaggacacggctttatattcctgtgcgaaggcatatgacgatgttttgacttcttattacatagcagcttttattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15934 JY8QFUQ01CFRQV productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1043 96.43 216/224 nt 95.98 215/224 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 10 17 8.10.17 [1.17.38.11] CTRDNPPLRSLEWLPFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); cttctggattcacctttggtgattatagtatgagttggttccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcaAaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15935 JY8QFUQ01DPD3M productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1004 95.87 209/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15936 JY8QFUQ01DP9T6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 943 93.9 200/213 nt 93.43 199/213 nt 8 8 X 8.8.X [X.17.38.X] null - No rearrangement found in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); acattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaAaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15937 JY8QFUQ01BQYCK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1027 96.8 212/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD1-1*01 F 3 8 8 8 8.8.8 [2.17.38.11] CAVNWNLDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttagcggctatgccatgagctgggtccgccaggctccagggaaggggctggactgggtctcatctattagttataatggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctccaaatgaacagcctgagagccgaggacacggccgtatattactgtgctgtgaactggaaccttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15938 JY8QFUQ01A0G35 No results +15939 JY8QFUQ01DAKH7 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttatagcatgcactGgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccttggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15940 JY8QFUQ01A2BDN productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15941 JY8QFUQ01DMHOM unproductive Homsap IGHV3-48*01 F 1048 98.61 213/216 nt Homsap IGHJ6*01 F 189 77.78 49/63 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [1.17.38.11] CVREGRGTGR#YGLDVW out-of-frame - tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccggccgcctacggtctggacgtctgggggccagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtnttccccctggcgccctgntccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15942 JY8QFUQ01BWC0Y unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 967 94.44 204/216 nt 93.52 202/216 nt Homsap IGHJ3*01 F (see comment) 124 72.0 36/50 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.16.38.11] CAKSPSQVGYYLD#VG out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccggcaaggggctggatgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagGactccgtgaagggccgattcaccatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttgggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15943 JY8QFUQ01DA9S4 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtctcccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15944 JY8QFUQ01BJDJL No results +15945 JY8QFUQ01CNN3Q unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 153 91.67 33/36 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found tctggattcaccttcagtaattactggatgtactgg +15946 JY8QFUQ01CEQ58 productive Homsap IGHV1-3*01 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15947 JY8QFUQ01AIVJA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15948 JY8QFUQ01BZ1HL productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 750 83.64 179/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15949 JY8QFUQ01DC2WW productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 921 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacccttctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15950 JY8QFUQ01B0T8V unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDQSCIVGPCGF*LL# out-of-frame + stop codons ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggtttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +15951 JY8QFUQ01DIKEE productive Homsap IGHV3-72*01 F 926 90.62 203/224 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-8*02 F 2 8 10 17 8.10.17 [1.17.38.11] CTRDTTDTGGQSFNGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggtttccccttcagtgaccacttcatggactgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctggggccaggggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagnacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15952 JY8QFUQ01AW8IU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 1 8 8 18 8.8.18 [1.17.38.11] CVKDLAHITHSSPWDDFDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggcaggggctggtgtgggtctcacgcattaatgaagatggaagtatcgtaacctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgagcagtctgagagccgaggacacggctgtgtattactgtgtaaaagacctcgcccacattacacatagtagcccgtgggacgactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgcctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgccatgcctggtccagggcttcttccc +15953 JY8QFUQ01AUJFH No results +15954 JY8QFUQ01DJYHX unproductive (see comment) Homsap IGHV3-9*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAK*FWSVAGRT#FDYW out-of-frame + stop codons ctctggattcaagtttgatgattatgccgcgcactgggtccggcaagctccagggaagggcctggaatgggtctcaggtattagttggaatggtggtagcacacgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaacgccctgtatctggaaatgaacattctgagaactgacgacacggccttatattactgtgcaaaatgattttggtcagtggctggtcggaccttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15955 JY8QFUQ01B4EGF productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15956 JY8QFUQ01CJP71 unproductive Homsap IGHV3-33*03 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.37.11] CARDGEQWLVWTL#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 195 in the user submitted sequence), (cause frameshift) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccgggacacggccgtgtattattgtgcgagagatggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15957 JY8QFUQ01CKQY0 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1012 90.95 221/243 nt 90.12 219/243 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [10.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); gggtccctgagactctcctgttcagcctctggattcatcttcagtgcctactggatgcactgggtccgccaagctccagggaaGggggctggtatgggtctcacgtactaataCcgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatggacagtctgagagccgaggacacggctgtttattattgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15958 JY8QFUQ01BYGN8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 8 17 8.8.17 [1.17.38.11] CAKDLVVTSIGPQGIHGHW in-frame + ctctgggttcacctttagcagctatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaagtatcagttttagtggtgagagaacatattatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacagtacatttgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaagatctggtggtgactagtattggcccccagggaatccatggccactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +15959 JY8QFUQ01B0TDL No results +15960 JY8QFUQ01APKQ3 unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15961 JY8QFUQ01DJGT0 unproductive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD2-15*01 F 1 10 7 X 10.7.X [1.17.38.11] CATIVPSSVTALINDQGRFYFDHW# out-of-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactgggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtcgtcgtggaactcag +15962 JY8QFUQ01DM0G8 productive Homsap IGHV3-30*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [1.17.38.11] CVKNDLSWGTIEHYFDYW in-frame - ctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15963 JY8QFUQ01CJ44M No results +15964 JY8QFUQ01BR2G2 productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 678 79.91 171/214 nt 79.44 170/214 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) ctctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca +15965 JY8QFUQ01A619F productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15966 JY8QFUQ01DA5RR productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +15967 JY8QFUQ01C8NI1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKAGYSSARTHMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagcaattttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttgtgagtggtagtggcgatagaacagactacgcagactccgtgaagggccggttcactatctccagagacaattccaagagtacactattcctgcaaatgcacagcctgagagtcgaggacacggccgtatattactgtgcgaaagctggatatagtagtgcgcgaacccacatggacgtctggggccaaggggtcgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15968 JY8QFUQ01B34XL productive Homsap IGHV4-39*03 F (see comment) 911 90.45 199/220 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-14*01 ORF 2 10 7 12 10.7.12 [1.17.38.11] YTREGPYYYGMDVW in-frame + Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgactccatcagtaatactgattactactgggtctggatccgccagaccccagggaagggactggagtggattgggagtatcgatttcagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccatagacacgtccgagaaccggttctccctgaggttgacctctatgaccgccgcagacacggccgtctattactatacgagagagggaccctactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15969 JY8QFUQ01BCB2R productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [0.17.38.11] CATSDVGARKFDYW in-frame + tggttacacctttaccagatatggtattagttgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcagcgtttccaatggtgacacaaactatgcacagaagctccagggcagagtcaccatgaccgcagacccatccacgagcacagcctacttggaactgaggagcctgacatctgacgacacggccgtatattactgtgcgacatctgacgttggagctcgaaagtttgactactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15970 JY8QFUQ01BLVTL productive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 937 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD6-19*01 F 1 10 7 10 10.7.10 [1.16.38.11] CAAYDSGWYKHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) tctctggtggctccgtcaacagtggtgattactactggacctggatccgccagcaccctgggaagggcctgagtggattgganacatctattacagtgggagcacttactacaatccgtccctggagagtcgagttaccatatcaatagacatgtctaagaaccagttctccctgaaagtgagctctgtgactgccgcggatacggccgtgtatcattgtgcggcgtatgacagtggctggtacaaacactggggccagggaaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15971 JY8QFUQ01CJZ1Y productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + tctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15972 JY8QFUQ01AEYN1 productive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15973 JY8QFUQ01BBI8L productive (see comment) Homsap IGHV4-61*02 F 970 93.24 207/222 nt 92.34 205/222 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD5-18*01 F 3 10 7 18 10.7.18 [2.17.38.11] CARVRARSNSHPGHSWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'AC' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagcagcACgtaggttactactcgacctggctccggcagcccgccggaaagggaccggagtggaAttgggcatatctatagtagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcggacacggccgtgtattactgtgcgagagtgagggcgcgcagtaatagtcaccccggccacagctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15974 JY8QFUQ01APCJA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15975 JY8QFUQ01AKMPH unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 932 96.5 193/200 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD6-13*01 F 2 3 8 X 3.8.X [X.17.38.11] CARGQQLRDFYY# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ccagctactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagacttttactactggggcagggaaccctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccgag +15976 JY8QFUQ01CPAF4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15977 JY8QFUQ01DMAVN productive (see comment) Homsap IGHV3-69-1*02 P (see comment) 917 92.09 198/215 nt Homsap IGHJ1*01 F, or Homsap IGHJ4*02 F (see comment) 126 75.56 34/45 nt Homsap IGHD7-27*01 F 2 8 8 6 8.8.6 [1.17.38.11] CARVEMDW in-frame + however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01DMAVN ; 7 AA in Homsap_IGHV3-69-1*02) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcagtgactataccatgaactgggtccgccaggctccagggaagggtctggagtgggtctcgtccattagtagtagtggtgattccatatactacgcagactcggtgaacggccgattcaccatcaccagagacaacgccaagaattcactttttctgcaaatggacagcctgagagccggggacacgggtgtttattactgtgcgagagttgaaatggactggggccagggaaccccggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +15978 JY8QFUQ01AUSQG productive (see comment) Homsap IGHV3-11*01 F 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.16.38.11] CARDDSCSGGSCYEYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 53 of V-REGION: 2 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) ctctggattcagtttcagtgactactacatgagttggatccgccaggctccagggaggggcgtggagtggttcatatattgatagcggtggtaccgccatgtactactcagactccgtgaagggccgattcaccatctccagggacaacgccaagaagtcactgtttctgcaaatgagtagcctgagagccgaagacacggccgtgtactattgtgcgagagatgactcttgtagtggtggtagctgttacgaatactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15979 JY8QFUQ01C8PPE unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggGggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactgggggccaggggagccctgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15980 JY8QFUQ01B471O productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15981 JY8QFUQ01C91CD productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15982 JY8QFUQ01AH1CO No results +15983 JY8QFUQ01CICCB unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 89.77 193/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 X 8.7.X [1.17.38.11] CAKNQQ*LR*##DWFDPW out-of-frame + stop codons in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactggGgggcaccgactccaaccCcctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaatcaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcccaggggcttcttccccccgag +15984 JY8QFUQ01DFJK6 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARDRRGYSYEMDYW in-frame - ctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15985 JY8QFUQ01CU4YF productive (see comment) Homsap IGHV1-2*02 F 939 93.46 200/214 nt 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCCA' (7 nucleotides at position 84 to 90 in the user submitted sequence), (cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacggGgcccctggacaAagggcttgagtggatgggatggatcaAACCCCAaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15986 JY8QFUQ01APCV8 No results +15987 JY8QFUQ01A7E8X No results +15988 JY8QFUQ01CE8U8 productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +15989 JY8QFUQ01CA87L productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 834 88.63 187/211 nt 88.15 186/211 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD6-19*01 F 1 8 7 20 8.7.20 [X.17.37.11] CVRDGRRTYNSGWYSLAAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 152 in the user submitted sequence), (cause frameshift) tgtctgccatcagcagtggtaactggtggagctgggtccgccagcccccagggaaggggctggaatggattggagaaatctcttatagtgggaccaccaagtacaaccggtccctcaagagtcgagtcaccatatcactagacacgtccaaaaccatttctccctgcagctgacttctgtgaccgccgcggacacggctgtctattattgtgtgagagatggtcgccggacctataacagtggctggtattcgttagctgcttttgatatctggggccaggggacagtggtcaccgtctcttccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +15990 JY8QFUQ01A58RQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcanttccccgaaccggtgacggtgtgcgtggaactca +15991 JY8QFUQ01APMPL unproductive (see comment) Homsap IGHV4-55*01 P, or Homsap IGHV4-55*02 P or Homsap IGHV4-55*03 P or Homsap IGHV4-55*04 P or Homsap IGHV4-55*05 P (see comment) 233 55.8 125/224 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 1 8 7 X 8.7.X [4.17.38.11] SCERHWTNLRSGP#LDYW out-of-frame + stop codons The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (8 AA in JY8QFUQ01APMPL ; 9 AA in Homsap_IGHV4-55*01), and low V-REGION identity (55,80% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgcctccataaaataggggtaattattactggaactggatccggcagccccgccgggaagggcctggaatggattggccgaatctatacaagtgggagcaccatctacaaccccgtccctcgggggtcgagtcaccatgactgtagacccgtccgagaatcagttcttcctgagactgagttctgtgaccgccgcagacacggccgtttatttttcgtgcgagagacactggacaaacctacggtcggggcccatttggactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +15992 JY8QFUQ01CODK0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 915 90.91 200/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctcctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15993 JY8QFUQ01CABWW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +15994 JY8QFUQ01DDTZN productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.37.11] CVSDLAGQKGFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 167 in the user submitted sequence), (cause frameshift) tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +15995 JY8QFUQ01CAC3H No results +15996 JY8QFUQ01BZFIE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +15997 JY8QFUQ01BCW8A No results +15998 JY8QFUQ01BL0H6 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +15999 JY8QFUQ01CE2FS productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16000 JY8QFUQ01DIG6K unproductive (see comment) Homsap IGHV3-7*01 F 974 93.67 207/221 nt 93.21 206/221 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons in CDR1-IMGT at codon 28 of V-REGION: 'GT' (2 nucleotides at position 12 to 13 in the user submitted sequence), (cause frameshift); cgacctctggaGTtcaacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16001 JY8QFUQ01DBFVZ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F or Homsap IGHV3-74*01 F or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 117 80.56 29/36 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found cctctggattcacctctcctagatactggatgaatt +16002 JY8QFUQ01AOPRK unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 1 8 7 X 8.7.X [1.17.38.11] CASANYDYVWGVIV#DYW out-of-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgaactc +16003 JY8QFUQ01AM5PU productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggGggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16004 JY8QFUQ01AHQN6 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 771 83.64 184/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARQSEPANNFNDPSRYFFDTW in-frame + Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcccgtgtctccatttccattaatgattactactggggctggatccgccagcccccaggaaagccgctggagtggattgggactgtccattcccttgggtacaattacaacaacccgtccctcaagagtcgactcaccatttccgcagacacgtccaggaatcagatctccctgaaactgacgtctgtgaccgccgcagacacggctgtctatttctgtgcgagacagagcgagcccgccaataacttcaatgacccaagtcgttatttctttgacacttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16005 JY8QFUQ01AS7A3 No results +16006 JY8QFUQ01B7UKD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 2 8 8 X 8.8.X [0.17.38.11] CAKDLVVTSIGPRES#GHW out-of-frame - in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); ctgggttcacctttagcagctatgccatgacttgggtccgccaggctccagggaaggggctggagtGgggtctcaagtatcagttttagtggtgagagaacatattatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacagtacatttgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaagatctggtggtgactagtattggccccagggaatccatggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16007 JY8QFUQ01BMX9G productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 89.3 192/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKNNNDFGDYDWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagttcctactggagttggatccggcagCcccccagggaagggcctggagtggattggttatgtctattatactggGgggcaccgactccaaccCcctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +16008 JY8QFUQ01B3S4F productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 991 94.98 208/219 nt 94.06 206/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); gcctctggattcactttcagGtagctactGggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16009 JY8QFUQ01C3ZVN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - tctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16010 JY8QFUQ01DQTXA No results +16011 JY8QFUQ01A8QCW productive Homsap IGHV3-48*01 F 1075 100.0 216/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16012 JY8QFUQ01B7KE2 No results +16013 JY8QFUQ01A8OIE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 890 90.7 195/215 nt 89.77 193/215 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-23*01 ORF 2 7 7 8 7.7.8 [2.17.38.11] CAGHGGSSHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) gcctctggattctccctgagggcaatggcatgagctgggtccgccaggctccagggaagggactggaatgggtctcagatataattggtagtggtgacacattctacgcagaatccgtgaagggccggttcaccatctccagagacaattccaagaacacactgtacttgcaaatgaagagcctgagggccgaggacacggccgtatattattgtgcgggtcatggtggaagttcccactggggccagggaaccctggtgaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16014 JY8QFUQ01A16J5 unproductive (see comment) Homsap IGHV3-38*01 ORF, or Homsap IGHV3-66*02 F (see comment) 722 82.55 175/212 nt 81.13 172/212 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD2-8*01 F 1 8 6 X 8.6.X [1.17.38.11] CARHLMVYALDV## out-of-frame - stop codons Low V-REGION identity (82,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'TCT' (3 nucleotides at position 80 to 82 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 71 of V-REGION: 'G' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); tctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaGggggctggagtgggtctcagTCTtatttagtactggcactgcatactacgcagactccGtgaaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +16015 JY8QFUQ01C4MC9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16016 JY8QFUQ01DAM0C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16017 JY8QFUQ01A0DA8 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARDRRPLREFDCW in-frame - ctctggattcaccctctccagctatgctatgcactgggtccgccagtctcccggcaaggggctagagtgggtggcagctatttcatatgatggaagtaaaatatattacgcagactccgtgaggggccgcttctccatctccagagacagttccaagaacactctgcatttgcaaatggacagcctgagacctgaggacacggctacatattactgtgcgagagatagacggccacttagggagtttgactgttggggccagggaaccccggtcgccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct +16018 JY8QFUQ01CNZ0L No results +16019 JY8QFUQ01BIEP0 productive Homsap IGHV3-9*01 F 981 94.93 206/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD6-13*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARKGGSNGRTWYNWFDPW in-frame - ctctggattcacctttaataattatggcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagtggtagtatagcgtatgcggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaattgaagacacggccttttattactgtgcaagaaagggaggaagcaatggcaggacctggtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16020 JY8QFUQ01CYS8I productive Homsap IGHV3-9*01 F 877 89.81 194/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame + tctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16021 JY8QFUQ01BLRPP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16022 JY8QFUQ01C3DOE productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 985 93.33 210/225 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 10 9 19 10.9.19 [1.17.38.11] CARGSSRGGNSDGVYYELDYW in-frame - tccggggacagtgtctctaccacccgtgctgcttggaactggatcaggcagtccccatcgggaggccttgagtggctgggaaggacatactacaggtccaagtggcttaatgattatgcagtgtctgtgaaaagtcgaattaccatcaatccagacacatccaagaaccagttttccctgcagttgaaatctgtcattcccgaggacacggctgtttattactgtgcaagaggttccagtcgcggggggaattctgatggggtctactatgaacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +16023 JY8QFUQ01AO5H2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 734 81.65 178/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-6*01 F 1 8 8 11 8.8.11 [1.17.38.11] CAKVDSSSAWDYW in-frame + Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaagtttcatgaatatgccatgatctgggtccgccaggctccaggcaagggtccggaatgggtctcgtctattagtagtactagtaaatacatctattatgcacagtcagtggagggccgattcaccatctccagagacgacgccgagaacgcactgttcctccagatgagcagcctgagtgtcgacgacacggctatctattactgcgcgaaagtcgatagcagttcggcctgggactattggggcccgggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16024 JY8QFUQ01CGLR6 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +16025 JY8QFUQ01C3W7S No results +16026 JY8QFUQ01CC4O1 productive Homsap IGHV1-3*01 F 966 94.86 203/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARWNNDLDYW in-frame + tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16027 JY8QFUQ01B8DLI productive Homsap IGHV3-7*01 F 881 90.23 194/215 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [0.17.38.11] CARVIPGRGNYAFDVW in-frame - ctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggttcagggcttcttccccca +16028 JY8QFUQ01DKEJD unproductive Homsap IGHV3-72*01 F 1038 96.41 215/223 nt 95.96 214/223 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD3-22*01 F 3 8 10 X 8.10.X [1.17.38.11] CVRGLHSNYYGMDV## out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgaccactacatggactgggtccgccaggctccagggaaggGggctggagtgggttggccgtagtagagacaaagttaacagttacagcacagaatacgccgcgtctgcgaagggcagattcaccatctcaagagatgaatcaaagaactcactgtatctgcaaatgaacagcctgaaaagcgaggacacggccgtgtattactgtgttagaggcctacacagtaattactacggtatggacgtcagggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16029 JY8QFUQ01AZPWT No results +16030 JY8QFUQ01C0TGG productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16031 JY8QFUQ01C9JN3 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccgggtgacggtgtcgtggcaactcag +16032 JY8QFUQ01DAT2D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16033 JY8QFUQ01ARS0N productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16034 JY8QFUQ01BT5YI productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F (see comment) 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 7 17 8.7.17 [1.16.38.11] CARVVTATIYTGSYYFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) tctatggtgcgtccttcagtgattactcctgggcctggatccgccagtcccagggaaggggctggagtggattggagagatcaatcatagtggaagcaccaactacaacccgtccctcaagagtcgaggcatcatatcaatagacatgtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacacggctgtatattactgtgcgagagtcgtcacggctacaatttatactgggtcctactactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16035 JY8QFUQ01CM3TN productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt 87.16 190/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.16.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaagggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcaccctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16036 JY8QFUQ01APJNE unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 898 91.55 195/213 nt 90.61 193/213 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 142 76.0 38/50 nt Homsap IGHD2-21*01 F 3 8 7 X 8.7.X [1.17.38.11] CTRELRLAAARDGVDI#W out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 55 to 56 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); tctgggttcaccgtcagtagcaagttcatgagctgggtccgccagggtccagggGAaaggggctggagtGgggtctcagttacttatcctgatggtactacacattatagagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacattttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16037 JY8QFUQ01B44GL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKLGVAATTWNFFDYW in-frame + ctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16038 JY8QFUQ01BLXM5 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 904 91.2 197/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-16*01 F 2 8 7 16 8.7.16 [2.17.38.11] CVRYDYSRLHRSNYFGPW in-frame - gcctctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtattacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16039 JY8QFUQ01BVJIX productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16040 JY8QFUQ01ATFZ4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgacaagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16041 JY8QFUQ01CT2LU productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1015 95.5 212/222 nt 94.59 210/222 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 2 7 10 10 7.10.10 [1.17.38.11] CTTLPWEPLDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 83 of V-REGION: 'G' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtatgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaactagaactgatggtgagacaacagactacgctgcacccgtcaaaggcagattcaccatctcaagagatgattcGaaaaaacacgttgtttcttcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtaccactcttccttgggagcctctcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaactggtcatcgcctgcctggtccagggcttcttcccccag +16042 JY8QFUQ01B6GM0 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*05 F 953 91.96 206/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 10 14 8.10.14 [1.17.38.11] CVVDIPEVGVGEFDYW in-frame - cctctggattctctttcacttatgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttgcccttattaaaagcaaaactagtggtgggacaacacactacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcagagaacacgttctatctacaaatgaatagactgaaaaccgaggacacagccgtgtattattgtgtcgtagatataccagaagttggtgtgggggaatttgactactggggccagggagccctggtttccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16043 JY8QFUQ01B7UDZ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 111 56.19 59/105 nt 8 8 X 8.8.X [1.17.X.X] null + No rearrangement found stop codons cctctggattcaccttcagtcgttatagcatgaactgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16044 JY8QFUQ01CJVPB productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F (see comment) 669 79.44 170/214 nt 78.97 169/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-10*01 F 2 8 8 21 8.8.21 [0.17.38.11] CARERRPGGYPNGYHHFYGMDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 208 to 208 in the user submitted sequence), (cause frameshift); ctctgatacaattagtcgttatggcatgcactgggtccgccaggctccaggcaaggggctggagtggctggcaattatttcatatgatggaaataggatatatgttggagactccgtgaagggccgcttcaccgtttccagagacaacgccgggaggactctgtttctgcaaatgaacagtctgagaggtgatgacaccgccacataCtttttgtgcgagagagcggcgtccgggtggctatccaaatggctaccaccatttttacggcatggacgtctggggccaagggaccagggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16045 JY8QFUQ01A1V6B productive Homsap IGHV3-11*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD1-20*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARVRKKSLDIWFDPW in-frame - ctctggattccccttcagtgatttctacatgatgtggatccgccaggctccagggaaggggctggagtgggtttcacacattagtggtagtggtagtaccatatactacgcagactctgtgaggggccgattcaccatctccagggacaacgccaagaaatcactgtttctgcaaatgaacagcctgaaagtcgaggacacggccgtctatttctgtgcgagagtccgcaaaaaatcattggacatctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16046 JY8QFUQ01BRJTL unproductive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD3-10*01 F 3 9 7 X 9.7.X [2.17.38.11] CAANLGHGSYF##IG out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ1*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 94 of V-REGION: 'T' (1 nucleotides at position 187 to 187 in the user submitted sequence), (cause frameshift); gtctctggtgactccgtcagcagtgataactggtggagttgggtccgccagaccccagggaaggggctggagtggattggagaaatctatcatggtgggaccaccaactacaatccgtccctcaaaggtcgagtcaccttatcggtcgacaagtccaagaaccaattctctctgagaatgacctctTtttaccgccgcagacacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattgggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16047 JY8QFUQ01AMIC0 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 972 94.47 205/217 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD3-22*01 F 3 9 7 11 9.7.11 [1.17.38.11] CAGLLTTFGLQSW in-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggtggctccatcagcagtagtaactggtggacttgggtccgccagcccccagggaaggggctggagtggattggggaaatctatcatggtggaaacacctactacaacccgtccctcaagagtcgagtcaccatatcactagacaagtccaagaaccaattctctctgaacctgaactctgtgaccgccgcggacacggccatatattactgtgcgggacttcttacgacttttggactgcagagctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccc +16048 JY8QFUQ01ACK3W unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 644 77.06 168/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (77,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtggcggtgtcgtggaactcag +16049 JY8QFUQ01AKB5X productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16050 JY8QFUQ01CXD17 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRGTREWSGIDYW in-frame - ctctggattcattttcagtaactactggatgcactgggtccgccaagctccagggaaggggctgctctgggtctcagtcattaatagtgacggcagtgaaattcactacgcggactccgtgaggggccgattcaccatctcccgagacaacgccaagaacacgctgtatttgcaaatggacaatctcagaggcgacgacacggctctatattattgtgtaagagggacaagggaatggagcgggattgactactggggtcagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16051 JY8QFUQ01AFKT3 productive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ3*01 F (see comment) 151 78.0 39/50 nt Homsap IGHD3-16*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARATNADVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccgagacctcactctatttgcaaatgaacaccctgagagccgaagacacggctgtctattactgtgcgagggcgactaatgccgacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16052 JY8QFUQ01C6P02 productive Homsap IGHV3-48*01 F 1009 95.89 210/219 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARVGATLSFDVW in-frame - gcctctggattcaccctcagtagctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtattagtagtggtaccatatactatgcagactctgtgaagggccgattcaccatctccagggacaatgccgagaactcactgtatctgcaaatgagcagcctgagagccgacgacacggctgtgtattactgtgcgagagtgggagcgacgctttcttttgatgtctggggccaagggacaacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16053 JY8QFUQ01B1RUY productive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*11 F or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 795 85.51 183/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [0.17.38.11] CVRVRDYEIGGDFW in-frame + tggaggcgccttcagcacctttcatatcacctgggtgcgacaggcccctggacaagggcttgtctggctggggaatatcattcctatttttggaacagtcgactacgcacgggggttccagggcagagtcacgattaccgcggacgaatccaccaacacagcctacatggagttgagcagcctgacatctgaggactcagccgtctatttctgcgtgagagttcgtgactatgaaattggtggtgacttctggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +16054 JY8QFUQ01CR2E2 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactc +16055 JY8QFUQ01CO9IL productive (see comment) Homsap IGHV3-11*01 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREYSSGEKGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggattcaccttcaatacctactacatgacctggatccgccaggctccagggaAaggggctggagtgggtttcacacattagtagtagtggcagtgtcacatactacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaattcactgtatctgcaaatgaacagcctgagagccgagggcacggccctgtattattgtgcgagagaatacagtagtggtgaaaagggctggttcgacccctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +16056 JY8QFUQ01B58AR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16057 JY8QFUQ01A5L2A No results +16058 JY8QFUQ01BRCWZ productive (see comment) Homsap IGHV4-4*07 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [1.17.38.11] CARGKDYYDTTGSLEDGFDIW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'T' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); tctctggtggctccataagaagttactactTggagttggatacggcactccgccgggaagggactggagtggatcgggcgcatatatgacagtggtagtacaaactacaatccctccctcaagagtcgagtcagcatgtcagtggacacgtccaagaaccaggtctccctgaagttgatctctgtgaccgccgcggacacggccatgtattattgtgcgagagggaaggattactatgatacaactggctccctcgaggatggttttgatatttggggccaagggacgatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +16059 JY8QFUQ01B6DIE No results +16060 JY8QFUQ01BOL9F productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16061 JY8QFUQ01CFH99 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16062 JY8QFUQ01AYOAK unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt 8 7 X 8.7.X [4.17.38.11] CARGGPTFMI (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggccccacttttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16063 JY8QFUQ01DOV01 unproductive Homsap IGHV3-21*04 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 102 66.67 34/51 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CARAVSHQVDV## out-of-frame - Other possibilities: Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ2*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); ctctggattcgacttcagtagatatatcatgaattgggtccgccaggctccagggaaAGggggctggagtgggtctcatccattagAttttgatagtaattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcgctgtttctgcaaatgaacagcctgagagccgatgacacggccgtgtattactgtgcgagagccgtgtcgcatcaggtggacgtctggggccaagggggccacggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +16064 JY8QFUQ01A9F0X productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 865 88.58 194/219 nt 87.67 192/219 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 6 13 10.6.13 [1.16.38.11] CARQLSGDYASFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 78 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 99 in the user submitted sequence), (cause frameshift) tctctggtgcctccatcaccagtggtactttttactgggcctggatccgccagcccccagggaaggggctggagtggttggcaatatctattctagtggtgtcgctattacaacccgtccctcaagagtcgagtcaccatgtccgtcgacacgtccaagaatgagttttccctgacactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16065 JY8QFUQ01BBWH9 productive Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + cctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16066 JY8QFUQ01AO0HA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctccggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16067 JY8QFUQ01DC1CW No results +16068 JY8QFUQ01COVW1 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 854 88.84 191/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 2 8 7 19 8.7.19 [1.17.38.11] CARSSDYLWGSYRYPYYFDYW in-frame - tctctggtgactccatcagtagttacttctggagttggatccggcagcccccagggaagggactggagtggattggatatgtctattacagtggaagtaccaagtataatccttccctcgaaagtcgagtcaccatatcattagacacgcccaacaaccagttctccctgagcctgacctatgtcaccgctgcggacacggccatatactactgtgcgagaagctctgattacctttgggggagttatcgttatccctactacttcgactactggagccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16069 JY8QFUQ01C1E4X productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD1-26*01 F 3 8 8 11 8.8.11 [1.17.38.11] CLKDHRGNYFDHW in-frame + ctctggattcgcctttagcagctatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtattagcgcatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtttctgcaaatggacagcctgagagtcgaggacacggccatatattactgtctgaaagatcatagagggaactactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16070 JY8QFUQ01CAQGF No results +16071 JY8QFUQ01BGO58 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt 99.54 216/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16072 JY8QFUQ01AXXC6 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDQRGYSYEMDYW in-frame - ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcagcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16073 JY8QFUQ01CQHHK productive Homsap IGHV3-9*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16074 JY8QFUQ01A39KY productive Homsap IGHV1-69*08 F 930 92.99 199/214 nt Homsap IGHJ4*03 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARDSNGYSSGYIDCW in-frame + tggaggctccttcggcagctacactatcacctgggtgcgacaggcccctggacaagggcttgagtggatgggaaggatcacccctatccttggttcaacaagctactcacagaagttccagggcagagtcacgattaccgcggacacattcacgggcacagcctacatggagctgagcagcctgacatctgaagacacggccgtatattactgtgcgcgagactcgaatggatacagttctggttatattgactgctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +16075 JY8QFUQ01DE7IJ No results +16076 JY8QFUQ01BL7SM productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16077 JY8QFUQ01DBWV7 unproductive Homsap IGHV3-64*02 F 958 93.98 203/216 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CVTCGDYSYEY## out-of-frame - Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) tctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactgggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16078 JY8QFUQ01A04CF No results +16079 JY8QFUQ01AYPNE productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactCccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16080 JY8QFUQ01CHYFI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD2-8*01 F 1 8 8 19 8.8.19 [2.17.38.11] CAKVFQVPGEHHSYYYGMNAW in-frame - gcctctggattcatctttactaactatgccatgagttgggtccgccaggctccagggagggggctggagtgggtctcaactatcagtgccaatggaggcaacacatactacgcggactccgtgaagggccgattcaccatctccagagacaactccaagaacacagtggatatgcaaatgaacagcctgaaagccgaggagacggccgtctattattgtgcgaaagtcttccaggtgcctggcgaacatcactcctactactatggtatgaatgcctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16081 JY8QFUQ01CB319 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16082 JY8QFUQ01B6P06 productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16083 JY8QFUQ01CG4JW unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CMNEFGYCSGG# out-of-frame - gctctggattcacttttagcagccatatgatgacttgggtccgccaggctccagggaaggggctggaatgggtcgcaagtattcgtgccagtggtggtaggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgttgtatttgcaaatgtacagtctgagagtcgaggacacggccttatattattgtatgaacgaattcggatactgtagtggtgggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16084 JY8QFUQ01AJYWV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CGKPIVGATGREMPVSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagcaactatgccatgaactgggtccgccaggttccaggggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16085 JY8QFUQ01BMEAE productive Homsap IGHV4-61*02 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16086 JY8QFUQ01CD50L productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16087 JY8QFUQ01APOZ1 productive (see comment) Homsap IGHV3-7*01 F 798 85.0 187/220 nt 84.55 186/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARERSAAGVVFFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); agcctctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaggggctggagAtgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgcaaatgaacagcctgcgagtcgaggacacggctgtgtatttctgtgcgagagagagatcagcagctggagtcgtcttctttgacttttggggccagggagccccggtcaccgtctccagagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16088 JY8QFUQ01BI3TS productive Homsap IGHV3-7*03 F 882 89.86 195/217 nt Homsap IGHJ6*03 F (see comment) 147 76.47 39/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcacctttagtaaccattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccgcggtcaacgtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +16089 JY8QFUQ01C7GQS productive Homsap IGHV3-7*01 F 882 89.86 195/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +16090 JY8QFUQ01B0KON productive Homsap IGHV3-7*01 F 901 90.41 198/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - gcctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16091 JY8QFUQ01C2QWE productive (see comment) Homsap IGHV3-72*01 F 1043 96.43 216/224 nt 95.98 215/224 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-11*01 ORF 2 8 10 13 8.10.13 [1.17.38.11] CVRGLHSNYYGMDVR in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgaccactacatggactgggtccgccaggctccagggaaggGggctggagtgggttggccgtagtagagacaaagttaacagttacagcacagaatacgccgcgtctgcgaagggcagattcaccatctcaagagatgaatcaaagaactcactgtatctgcaaatgaacagcctgaaaagcgaggacacggccgtgtattactgtgttagaggcctacacagtaattactacggtatggacgtcaggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16092 JY8QFUQ01AK0GH unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD4-11*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CAKVGGDVRSRPH*LL# out-of-frame - stop codons ctctggattcacctttagcaactatgccatgagttgggtccgccaggctcaagggaaggggctggactgggtctcagatattagtaatagtggtggtgacacattctacgcaggctccgtgaagggccgcttcaccatctccagagacaattccaggaacactctatatctgcaaatggacagcctgagagccgaggacacggccgtgtattactgtgcgaaagtggggggtgatgtccgctcgagaccgcattgactactgggggccgggaaaccctggtctccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16093 JY8QFUQ01B9Q0Q productive Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + cctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16094 JY8QFUQ01B25CZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatcccccgaccagccccctaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +16095 JY8QFUQ01B0SLO productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 930 92.99 199/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-25*01 F 1 8 8 15 8.8.15 [0.17.38.11] CARHEGYNSRYYYFGYW in-frame + tggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16096 JY8QFUQ01AG2CI unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16097 JY8QFUQ01BO5PG productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 91 to 96 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggacCtggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16098 JY8QFUQ01BQ0GT productive (see comment) Homsap IGHV3-9*02 F 833 87.16 190/218 nt 86.7 189/218 nt Homsap IGHJ2*01 F (see comment) 157 77.36 41/53 nt Homsap IGHD4-11*01 ORF 3 8 8 17 8.8.17 [1.17.38.11] CARAPSVTFSGQGHYYDLW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); gcactggattcagctctgagaattatgccatgcactgggtccggcagcctccaCgggaagggcctagagtgggtctcacacatcagttggaatggcgaaggcatcgactacgcggactcagtgaagggccgattcaccgtctccagagacaacggcaagaattccctgtatttgcaaatgaacagtctgacaactgacgacacggccttgtattactgtgcaagagccccttcagtcacattcagcgggcaggggcactactatgatctctggggccgtggcaccctggtcgtggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16099 JY8QFUQ01BV2T6 unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 764 84.19 181/215 nt Homsap IGHJ4*02 F (see comment) 105 68.75 33/48 nt Homsap IGHD3-16*02 F 1 8 7 X 8.7.X [1.17.38.11] CARGPGSGSNSYYFGLL# out-of-frame + Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) tttatggtgcctccttcagcggacactactggggttggttccgccagcccccagggaaggacctggagtggatcggggaagtcagtcatggcggaagcatcaagttcaacccgtccctcaagagccgcgtcaccatgttagtagacacgtccacgagccgggtttctctgaggctgaccgctgtcaccgccgcggacacggctatgtattactgtgcgaggggcccaggttcggggagtaatagttattattttggattattggggcccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaactcag +16100 JY8QFUQ01BFY14 No results +16101 JY8QFUQ01C1H7H unproductive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [1.17.38.11] CASRLRSSG#YW out-of-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +16102 JY8QFUQ01ARSU8 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16103 JY8QFUQ01BFEPW productive (see comment) Homsap IGHV1-69*08 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*03 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARDSNGYSSGYIDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); tggaggctccttcggcagctacactatcacctgggtgcgacaggcccctggacaagggcttgagtggatggGgaaggatcacccctatccttggttcaacaagctactcacagaagttccagggcagagtcacgattaccgcggacacattcacgggcacagcctacatggagctgagcagcctgacatctgaagacacggccgtatattactgtgcgcgagactcgaatggatacagttctggttatattgactgctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16104 JY8QFUQ01AVYXK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [2.17.38.11] CARDTLEVVSNMDDAFDFW in-frame - gcctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaagggcttggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16105 JY8QFUQ01CPL1S productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt 91.4 202/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtGataattttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16106 JY8QFUQ01AUJE9 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - ttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16107 JY8QFUQ01AZ3Q8 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 7 12 8.7.12 [1.17.38.11] CARAPGWMNPFDFW in-frame - ctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16108 JY8QFUQ01DA9VQ productive (see comment) Homsap IGHV3-7*03 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 7 8 8 7.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctccggattcattttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtcccaggggcttcttcccccag +16109 JY8QFUQ01CY2CV productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + tctctggtggctccatcagcagcagtagttactactcgacctggctccggcagcccgccggaaagggaccggagtggattgggcatatctatagtagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16110 JY8QFUQ01AHHJ6 productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYHFDYW in-frame + ctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16111 JY8QFUQ01CRSIV productive (see comment) Homsap IGHV3-48*01 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); tctggtttcaccttcaggagctctggcatgaactGgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16112 JY8QFUQ01BQ3I3 productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 881 90.23 194/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [0.17.38.11] CAKEEFDTGWTQPGDW in-frame - ctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16113 JY8QFUQ01COJUU productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 823 85.33 192/225 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD4-17*01 F 3 10 9 17 10.9.17 [1.17.38.11] CAREETTRPPSYYKGLDVW in-frame - tccggggacagcatttctagtaagacagctgcttggaattggatcagacagtcctcatcgagaggccttgaatggctgggaagggcatattacaggtccaagtggtataatgaatatggagaatctgtgaagggtcgcataacgttcagtggagacacatcgacgaatcagttctccctgcacctggactctgtgactcccgacgacacggctgtctatttctgtgcaagggaggagactacacgtcccccctcgtattacaaaggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16114 JY8QFUQ01DO25D productive Homsap IGHV4-30-4*07 F, or Homsap IGHV4-31*01 F or Homsap IGHV4-31*02 F or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F or Homsap IGHV4-31*06 F or Homsap IGHV4-31*07 F or Homsap IGHV4-31*08 F or Homsap IGHV4-34*09 F or Homsap IGHV4-59*06 F (see comment) 248 75.0 69/92 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 X X 18 X.X.18 [X.X.30.11] CARSAYCGADCYSADYLQHW in-frame + Low V-REGION identity (75,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggctccgtcagcaacacgtctaagaaccaattctccctgaagttgacctctatgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccggaccagccccaaaggtcttcccggctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +16115 JY8QFUQ01C7O89 No results +16116 JY8QFUQ01A6QIC No results +16117 JY8QFUQ01CDBW9 No results +16118 JY8QFUQ01BBA7A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggccactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +16119 JY8QFUQ01DE2P3 productive Homsap IGHV3-72*01 F 943 91.89 204/222 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 3 8 10 15 8.10.15 [1.17.38.11] CVRVVREGAVTTFFDYW in-frame - tctggattcaccttcagtgactattatatagactgggtccgccaggctccagggaaggggctggagtggtttggccgttctagaaacaaagtgaatagttacagtacagcatacgccgcgtctgtgagaggcagattcagcttctcaagagatgattcaaagaacgcactgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtgtattattgtgttagagtcgtgagggagggcgcggtgaccacattctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgaggcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccag +16120 JY8QFUQ01BI8MT unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRRGDGSGQ##DAFDIW out-of-frame - stop codons ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaaggggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16121 JY8QFUQ01C2XG5 productive Homsap IGHV3-30*15 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame + ctctggattcacctttagtagatattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttatatcatacgatggaagtagaagaatctacgcagactccgtgaagggccgattcaccatctccagagacacttccaagaacacggtgtatctgcaaatgagtagcctgagacctgaggacacggctgtgtattactgtgcgagagatgagctgccttgggatacaatagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +16122 JY8QFUQ01C4QBN productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 896 90.37 197/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-1*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDHFLQPGRDYYYGMDVW in-frame + cgtctggatttcccttcagaacccatggcatgcactgggtccgccaggctccaggcaaggggctggagtggctggcagttatctggtgggatggaagtcagaaatactatgaagattccgtgaagggccggttcaccatctccagagacaattctaagaacacggtttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtgcgagagatcatttcctacagccggggcgagactactactatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16123 JY8QFUQ01CGF0M No results +16124 JY8QFUQ01BPRAJ productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 692 80.47 173/215 nt 80.0 172/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); tctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaAaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtgggaactcag +16125 JY8QFUQ01DKJKX No results +16126 JY8QFUQ01A3RQE productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'T' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatTgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16127 JY8QFUQ01CUN7T productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 806 85.78 187/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16128 JY8QFUQ01AOSX6 productive Homsap IGHV4-61*02 F 884 89.14 197/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.38.11] CARDFGGSYNLVAYW in-frame + tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16129 JY8QFUQ01A6H3Y No results +16130 JY8QFUQ01CVYKI productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARDPGPSTPWYYFDYW in-frame + ctctggattcaccgttaataatcattggatgagttgggtccgccaggctccagggaaggggctggagtggctggcctacataaactatgatggaactgtgaaatactatgtggactctgtgaagggccgattcaccatctccagagacagcgccaggaactcactgtctctgcaaatgaacagcctgagagtcgaggacacggctgtatactactgtgcgagagatcccgggccttcgaccccctggtactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16131 JY8QFUQ01BLBJQ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDPGNYWGYYYDS## out-of-frame + gtctggattcacctttagtgattatgccttgagctgggtccgccagactcccgggaaggggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgagagatccgggaaattattggggatactattatgactcttgggggcctgggaaccctggtcgccgtctcctcagcatcccctgaccagccccaaggtcttccgctgagcctcctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +16132 JY8QFUQ01A6BZO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-14*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CTKDYPDGRLLNHVLPFFDTW in-frame - cctctggattcacgtttgacgactatgccatgagttgggtccgccaggctccagggaaggggccggagtgggtctcaggtattattcctaatagtcgtgacagacactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagagcacagtgtatctgcaaatgaacaacctcagaggcgaggacacggccgtatattactgtacgaaagactatccggacggccgcctgctaaatcacgtccttcccttttttgacacttggggcgagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16133 JY8QFUQ01AOQRW productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 765 83.87 182/217 nt 83.41 181/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CAKVKGYGGNWFQPHFDRW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); ctctggattcaccttcggcagttataggatgagctgggtccgacaggcGtccagggaaggggctggagtgggtctcaggtatctacggtggtgatggtacatcattttacgcagacttcgcgaagggccgattcaccgtctccagagacaattccaaggacacggtctatctgcagatgaacggcctgagagtcgaagactcggcccgttattattgtgcgaaagtgaagggctacggcggcaattggttccagcctcactttgaccgctggggccagggcaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16134 JY8QFUQ01CX2EQ productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 985 93.33 210/225 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 10 9 19 10.9.19 [1.17.38.11] CARGSSRGGNSDGVYYELDYW in-frame + tccggggacagtgtctctaccacccgtgctgcttggaactggatcaggcagtccccatcgggaggccttgagtggctgggaaggacatactacaggtccaagtggcttaatgattatgcagtgtctgtgaaaagtcgaattaccatcaatccagacacatccaagaaccagttttccctgcagttgaaatctgtcattcccgaggacacggctgtttattactgtgcaagaggttccagtcgcggggggaattctgatggggtctactatgaacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttctt +16135 JY8QFUQ01BB9AK productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 836 87.91 189/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.38.11] CARGRTVVTVIDYIDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctgggggActccattagtggttactattggacgtggatccggcagAcccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16136 JY8QFUQ01CZX8Z productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16137 JY8QFUQ01DMUAK productive Homsap IGHV3-9*01 F 923 91.74 200/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVKGAGTTVNWFDIW in-frame - cctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctagaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16138 JY8QFUQ01BUZ5L productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16139 JY8QFUQ01CEDUW No results +16140 JY8QFUQ01BXDL3 unproductive Homsap IGHV1-3*01 F 961 94.84 202/213 nt 94.37 201/213 nt Homsap IGHJ2*01 F (see comment) 85 62.26 33/53 nt Homsap IGHD5-24*01 ORF 1 8 7 X 8.7.X [0.17.38.11] CARWNNDLDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccaggggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16141 JY8QFUQ01DK9VC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 743 82.57 180/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAMRFCGGPECYPYLDNW in-frame + Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctgggttcacattcagtaactactggatccactggatccgccaagctccaggaaaggggctagagtgggtcgcacgtattaatgatgctggaaagcgtgccgacttcgcgactttcgtgaagggccgattctccatctcccgagacaacgccaagaacacagtgtatctggaaatgactagtctgagagtcgacgacacggctgtctatttttgtgcaatgcgattttgtggtggtcctgagtgctacccttatcttgacaactggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +16142 JY8QFUQ01ACBE5 No results +16143 JY8QFUQ01BCC5N unproductive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*05 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD3-10*02 F 2 8 8 X 8.8.X [0.17.38.11] CARVRGR***RLLCRG##AMDVW out-of-frame - stop codons Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); tggatacaccttccccgaccactatgtacactgggtgcgacaggcccctggacaagggcttgagtggatgggacggatcaGgccctaacactggcggcgcacactatggacagaggtttcagggcagggtcaccatgaccagggacacgtccatcaccacagtctacatggaattgagcaggctgagtccggatgacacggccgtgtattattgtgcgagagttcgggggagatgatgatgacggttactatgtcggggaggacgctatggacgtctggggccaggggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16144 JY8QFUQ01CZBMT productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16145 JY8QFUQ01CTTTK unproductive (see comment) Homsap IGHV3-9*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CVKRSKGQQL#YYFENW out-of-frame - stop codons cctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagtcagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16146 JY8QFUQ01B10W1 No results +16147 JY8QFUQ01AQSIL productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - gtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +16148 JY8QFUQ01DRFNR No results +16149 JY8QFUQ01A975A No results +16150 JY8QFUQ01AXLKO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [1.17.38.11] CVRYDYSRLHRSNYFGPW in-frame + tctctggattcaccttcatcagttatggcatgagttgggtccgccagtttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16151 JY8QFUQ01C2M15 No results +16152 JY8QFUQ01AI276 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16153 JY8QFUQ01BFHQW No results +16154 JY8QFUQ01BM5VS productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16155 JY8QFUQ01CB28K productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16156 JY8QFUQ01AWMK6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 140 86.49 32/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcatgtttaggaactatgccatgagttgg +16157 JY8QFUQ01C5MW0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16158 JY8QFUQ01CI7LR unproductive (see comment) Homsap IGHV3-48*01 F 835 88.26 188/213 nt 87.79 187/213 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [0.16.38.11] CARASTFYYDGSGYRDA#FDIW out-of-frame - stop codons in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) ctggcttcagtttgagtacttataccatgaactgggtccgccaggctccaggaagggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgctttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16159 JY8QFUQ01ATDOT productive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16160 JY8QFUQ01DW9YA productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt 97.36 221/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 79 of V-REGION: 'G' (1 nucleotides at position 150 to 150 in the user submitted sequence), (cause frameshift); tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcGaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16161 JY8QFUQ01AOTQ3 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 88 64.0 32/50 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW# out-of-frame + in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaaccCcctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctgggggccaagggacaaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +16162 JY8QFUQ01BI2RW No results +16163 JY8QFUQ01ASBUA unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +16164 JY8QFUQ01AXDN2 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + cctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +16165 JY8QFUQ01DA6VC productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 762 83.18 183/220 nt 82.73 182/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); tctctgtgactccatcagtagtactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16166 JY8QFUQ01CYF81 unproductive Homsap IGHV4-34*10 F 818 86.98 187/215 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD4-23*01 ORF 3 8 7 X 8.7.X [1.17.38.11] CARNTNYGGNSGDYFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccaagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16167 JY8QFUQ01A6CSB productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 909 91.24 198/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKVSGNSRTYWYLDIW in-frame + ttctggatacaactttcccagatattggatcgcctgggtgcgccagattcccgggagaggcctggagtgggtggggatgatctatcctggtgactctgagaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacgcgtccatgaacaccgcctacctgcagtggagcagcctgaaggcctccgacaccgccatatacttctgtgcgaaggtctctggtaactctcgaacctactggtacctcgatatctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +16168 JY8QFUQ01AOKUM productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*07 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 914 91.28 199/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDREDSSGYYFFRDGFDIW in-frame - cctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagatcgtgaagatagtagtggttattacttcttccgtgatggttttgatatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16169 JY8QFUQ01C2V0B productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 885 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 7 8 10 7.8.10 [1.17.38.11] CTKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift)in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) tccggattcaccttagtagttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16170 JY8QFUQ01BGZU9 productive Homsap IGHV3-7*01 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - ggctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +16171 JY8QFUQ01BTX33 No results +16172 JY8QFUQ01DFILC No results +16173 JY8QFUQ01DBH3Q productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt 88.48 192/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKYVEGWSYTGGYYNSYAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'A' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); ttctggattcgcctttagccgttatgccatgacttgggtccgccagactccagggagggggctggagtgggtctcaggtctcagtggtagtggtgaAtagcacatactactcaaacAtccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggaggggtggtcatatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16174 JY8QFUQ01DH6UA No results +16175 JY8QFUQ01C8PK9 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 987 94.55 208/220 nt 93.64 206/220 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [2.17.38.11] CVRRGMVAGRYDAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtagttatagGcatgaactGgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16176 JY8QFUQ01CZH3T productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 824 86.7 189/218 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGFSAWGQDAFDIW in-frame - tctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16177 JY8QFUQ01B7PFH productive (see comment) Homsap IGHV3-7*01 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 192 to 192 in the user submitted sequence), (cause frameshift); cctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagcCcccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +16178 JY8QFUQ01DB4UP productive (see comment) Homsap IGHV3-7*01 F (see comment) 724 81.94 177/216 nt 81.48 176/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); tctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggGggccagagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16179 JY8QFUQ01A6SVN productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16180 JY8QFUQ01C2MY9 productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16181 JY8QFUQ01AJHM4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRGTREWSGIDYW in-frame + ctctggattcattttcagtaactactggatgcactgggtccgccaagctccagggaaggggctgctctgggtctcagtcattaatagtgacggcagtgaaattcactacgcggactccgtgaggggccgatttaccatctcccgagacaacgccaagaacacgctgtatttgcaaatggacaatctcagaggcgacgacacggctctatattattgtgtaagagggacaagggaatggagcgggattgactattggggtcagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +16182 JY8QFUQ01CJ5TF productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16183 JY8QFUQ01CH2BP productive Homsap IGHV3-9*01 F 887 89.91 196/218 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDVTSESHFFALDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctcgggattcaagtttgatgaatatgccatgcactgggtccggcgagttccagggaggggcctggagtgggtctcagttataagttgggatggtgatgacatcgcctatgcggactctgtgaagggccgattcagcatctccagagacaacgccaagaactccctgtacctggaaatgagcagtctgagagttgaggacacggccttctattactgtgcaaaggatgtcacatctgaaagtcacttcttcgctttggacgtctggggccaagggaccgcggtcaacgtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16184 JY8QFUQ01CXWET productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16185 JY8QFUQ01AUQ2Z unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CATDGVGSTVKLMVMGPFDFR in-frame - stop codons in CDR1-IMGT at codon 35 of V-REGION: 'AAC' (3 nucleotides at position 18 to 20 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); ctctggattcgtcctttAACgaactgatgccatgggctgggtccgccaggctccagggaaggggttggagtGgggtctcatctattagtactagtgggactaactcatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagcaagcgctttatctgcagatgaacagcctgagagccgaggacacggccgtttattactgtgcgacagatggagtagggtctactgtgaagttgatggttatgggcccttttgacttcaggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16186 JY8QFUQ01DA179 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 10 6 11 10.6.11 [1.17.38.11] CARSYGFSRFDPW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 91 in the user submitted sequence), (cause frameshift) tctctggtggctccatcaccagtagtctttaccgctggggctggatccgccagtccccagggaagggcctggagtggatagggaatatctttatggtgggaccacctactacaacccgtccctcaagagtcgagtcaccttatccatagacacgtccaagagccagttctccctgaagctgtcctctgtgaccgccgcagacacggctctatattactgtgcgagatcgtacggtttctctcggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16187 JY8QFUQ01AN2H8 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgGggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16188 JY8QFUQ01C3KAU productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 874 89.04 195/219 nt 88.13 193/219 nt Homsap IGHJ6*02 F (see comment) 188 78.69 48/61 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CAREGGRGYDMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtatctatgccatgacctgggtccgccaggctccagggaaggggctggagtggatttcCatttatcactgataGggggtagtacccaatactacgcagactctgtgaagggccgattcaccgtctccagggaccaagccaagaactcactgtatctacaaatgaacaacctgggagtcgaggacacggctgtgtattattgtgcgagagaggggggacgtggctacgatatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16189 JY8QFUQ01B4Z8B productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16190 JY8QFUQ01AMBFI unproductive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 1044 98.16 213/217 nt 97.7 212/217 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-2*02 F 2 8 7 X 8.7.X [2.17.38.11] CARGGRRQLA##EYFQHW out-of-frame - stop codons in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); agcctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttaCtttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagggggtcggcgtcagctggcatactgaatacttccagcactggggccagggcaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16191 JY8QFUQ01A9E7L productive Homsap IGHV1-18*01 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt 8 8 8 8.8.8 [0.17.38.11] CARGDYFDHW in-frame + tggttacacctttaccagctatggtctcagctgggtgcgacaggcccctggccaagggcttgagtggatgggatggatcttcgtttttaacggtaacacaaaatatgcacagcacctccagggcagagtcaccatgaccacagacacatccacggacacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagaggtgactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16192 JY8QFUQ01ASGEG productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 761 83.49 182/218 nt 83.03 181/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [2.16.38.11] CARDSALFGYARYDAMDAW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gcctctggattcacgtttggcagccacgccatgagctggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16193 JY8QFUQ01B1F9O productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagtttcagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16194 JY8QFUQ01AWUPN productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 7 13 8.7.13 [1.17.38.11] CASVGVEATVAFQYW in-frame - Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattcaccgtcagtgatagttacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcgattatttataggggaggtaccacatattatgccgactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctatatcttcaaatgaacaccctgagaggtgaggacacggctctatattactgtgcgagcgtcggagtggaagctacagtcgcctttcaatactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16195 JY8QFUQ01DPHRY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARGPRSRGYGMDVW in-frame - agcctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16196 JY8QFUQ01BYBO2 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 7 8 X 7.8.X [1.17.38.11] CARPGGDCLL*WW*#CYDPW out-of-frame - stop codons in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) ctctggattcagctcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccagggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16197 JY8QFUQ01C8UBY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16198 JY8QFUQ01CNQC8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - cctctgaattcaccctcagtgactactacatgagctggatccgccaggctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16199 JY8QFUQ01B9GN0 productive Homsap IGHV3-48*01 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 8 22 8.8.22 [2.17.38.11] CARGHFDYYGSGSYYRDLYYFDNW in-frame - gcctctggattcaccttcagtagttataagatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacatcagtggtagtagtactaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtatctgcaaatgaatggcctgagagccgaggacacggctgtgtattactgtgcgagaggtcacttcgattattatggttcggggagttattatagggacttgtattattttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16200 JY8QFUQ01BF7CI No results +16201 JY8QFUQ01B5JGV productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 900 90.78 197/217 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKDMVSGPVLFGMDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtgaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagtcatatcgtacgagggacgtagtgaagactatgcagactccgtgaagggccgattcgtcatctccagagacaactccaagaacaccctgtatctactaatgaacagcctgagaggtgaggacacggctgtttactactgtgcgaaagatatggttagcggacctgtcctcttcggtatggacgtctggggccacgggaccaaggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16202 JY8QFUQ01DPLES unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt 94.95 207/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cctctggattcacctttagaagctatgccatgagctgGggtccgccaggttccagggaaggGggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16203 JY8QFUQ01BY5NQ No results +16204 JY8QFUQ01A08XO productive Homsap IGHV4-61*01 F 1095 100.0 220/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame + ctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16205 JY8QFUQ01CMX1Z productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16206 JY8QFUQ01C9N4Z productive (see comment) Homsap IGHV1-3*01 F 876 90.19 193/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDGEPLGGDYFDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcacttcttatgctgtaaaactgggtcgccaggGcccccggacaaaggcttgagtggatgggatggatcaacgctggcacgggtaacacaaaatattcacagaagtttcagggcagagtcaccattaccagggacacatccgcggacacagtcttcatggagctgagcagtctaagatctgaagacacggctgtgtattattgtgcgagagatggggagccactgggaggcgactactttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16207 JY8QFUQ01AURES productive (see comment) Homsap IGHV1-2*02 F 835 88.26 188/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [0.17.37.11] CAKHPLRSTSGHSYLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 120 in the user submitted sequence), (cause frameshift) tggatacatattcaccgAccttttatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggatccatcaatcccaacagtggtgtcacaacctacgaagagaagtttcgggcagggtcaccatgaccagggacacgtccatcactacagcctacatggaactgacaagccttacatcagacgacacggccgtatattactgtgcgaaacatcctcttcgatcaacaagtggacattcctacttagattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16208 JY8QFUQ01BLVJA productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgagacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16209 JY8QFUQ01BDJMP unknown (see comment) Homsap IGHV3-64*02 F, or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons ctctggattcacctttagtaaccattggatgaactgggtccgccaggccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16210 JY8QFUQ01BC6Y9 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame + ctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +16211 JY8QFUQ01A7JXF productive (see comment) Homsap IGHV3-13*01 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); agcctctggattcacgGttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16212 JY8QFUQ01B7R7S productive Homsap IGHV3-11*01 F 828 87.1 189/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CVREVTGVWDWFDPW in-frame - ctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +16213 JY8QFUQ01BMPPT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - cctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16214 JY8QFUQ01DQ7TD unproductive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDKGWSGYGMDV## out-of-frame + cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaaggggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16215 JY8QFUQ01CYLZC productive Homsap IGHV1-69*08 F 930 92.99 199/214 nt Homsap IGHJ4*03 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARDSNGYSSGYIDCW in-frame + tggaggctccttcggcagctacactatcacctgggtgcgacaggcccctggacaagggcttgagtggatgggaaggatcacccctatccttggttcaacaagctactcacagaagttccagggcagagtcacgattaccgcggacacattcacgggcacagcctacatggagctgagcagcctgacatctgaagacacggccgtatattactgtgcgcgagactcgaatggatacagttctggttatattgactgctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagtctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +16216 JY8QFUQ01AWLNY productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1034 93.99 219/233 nt 92.7 216/233 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 10 9 19 10.9.19 [3.17.38.11] CARASRRDRQSDRNYYELDFW in-frame - Potentially, because of detected insertion/deletion in FR1-IMGT at codon 26 of V-REGION: 'C' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'A' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); gtgccatcCtccggggacagtgtctctagcaacagtgccacAttggaactggatcaggcagtccccaacgggaggccttgagtggctgggaaGggacatcctacaggtccaaatggtatagtgattatgcggtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcaattgaactccgttagtcccgaggacacggctgtgtattactgtgcaagagcttccagacgcgatcgtcagtctgatcggaactactatgagctggacttctggggccagggaatcttggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16217 JY8QFUQ01CGUO4 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 743 82.57 180/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 124 72.0 36/50 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [1.17.38.11] CARIWDSWSGAFDV## out-of-frame + Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) cctctggattcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtgggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggacgtggtcatcgcctgcctggtccagggcttcttccccc +16218 JY8QFUQ01B34QT productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-9*01 F 3 8 7 19 8.7.19 [1.17.38.11] CAKVLSGDFQRIMIRPFFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 91 to 96 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagtttctacCtggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgaaggtgttgtcgggagactttcaacggattatgataagaccgttctttgaccactggggccagggaacccagctcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16219 JY8QFUQ01CABXM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.37.11] CAKDASRYYYNSYCDNW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 214 in the user submitted sequence), (cause frameshift) cctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttattttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16220 JY8QFUQ01C4HDT unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 89 51.88 69/133 nt 8 6 X 8.6.X [1.17.12.X] null + No rearrangement found ctctggattcaccttcagctcccattggatgagctgggtccgccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16221 JY8QFUQ01DG1D7 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 289 58.9 129/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (58,90% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. gcctctggattcacctttggcctctatgccatgaactgggtccgccagactccagggaaggggctggagtggctcgcaactattagtggcgttggtgcttactacatctactattttgacttatgggaccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16222 JY8QFUQ01A72BF productive (see comment) Homsap IGHV4-61*01 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGAYWNLIRDW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 67 of V-REGION: 'TATAATCCCCTG' (12 nucleotides at position 111 to 122 in the user submitted sequence), (do not cause frameshift); tctctggtggctccgtcagcagagatatttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatgtatcacagagggaacactaagTATAATCCCCTGtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtgggtccggtggggcctactggaatttgatccgggactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +16223 JY8QFUQ01B1B9K unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16224 JY8QFUQ01CUD8G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame + ctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16225 JY8QFUQ01AODUI productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 937 92.24 202/219 nt Homsap IGHJ6*02 F (see comment) 205 83.05 49/59 nt Homsap IGHD5-24*01 ORF 3 8 8 11 8.8.11 [2.17.38.11] CARPRYGYGLDVW in-frame - Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) ggttctggatacgactttaacaactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatcatctttcctggtgactctgatatcagatatagtccgtcgttccaaggccaggtcaccatctcagtcgacaagtccatcggcaccgcctacctgcaatggagcggcctgaaggcctcggacaccgccacttattattgtgcgagacctagatacggatacggcttggacgtctggggccaagggaccacggtcaccgtctcctcagccccccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16226 JY8QFUQ01CAJ7U No results +16227 JY8QFUQ01BBMOA unknown (see comment) Homsap IGHV3-15*08 F, or Homsap IGHV3-30*14 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*03 F 101 54.81 57/104 nt X X X X.X.X [X.X.34.X] null + No rearrangement found ctctggattcaccgtcagttccaatctccagcgacttttccaaggaaactctgtctcttcaagaaatagacctgaaaattgacgacacgccgagccgtttctagtgtagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16228 JY8QFUQ01DOQOV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKCKAPGKVDWFDPW in-frame + ctctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctggtaaggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +16229 JY8QFUQ01C4GEG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16230 JY8QFUQ01BOVRG productive Homsap IGHV3-7*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + tctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16231 JY8QFUQ01CDJ5P unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 854 88.84 191/215 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD5-18*01 F 3 10 7 X 10.7.X [1.17.38.11] CARGGIYL*Q#PW out-of-frame + stop codons The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01CDJ5P ; 8 AA in Homsap_IGHV4-59*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgactccatcagcggcagtaccaactactggacctggatccggcagcccccaggaaagggactggaattcattgggtatatctataacagtggcaacaccaactacaacccctccctcaagagccgagtctccatttctttggacaggtccaagaaccagttctccctgaggctgacccccgtgaccgctgcggacacggccatgtattactgtgcgagggggggcatatacctatgacagcccgtggggccagggaacccgggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16232 JY8QFUQ01CHVZZ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD4-11*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CAKQTIFDYYYYG#LDVW out-of-frame + Other possibilities: Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) ctctggattcatgtttagtagctttcccatggcctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggttttggacgtctggggtcaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16233 JY8QFUQ01A4HT0 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 65 of V-REGION: 2 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggagggggctggagtgggtctctggtattaatcggaatggtgatagcaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16234 JY8QFUQ01BGNLQ No results +16235 JY8QFUQ01AD4IM unproductive (see comment) Homsap IGHV3-7*01 F 964 93.61 205/219 nt 92.69 203/219 nt Homsap IGHJ4*03 F (see comment) 78 62.5 30/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [2.17.38.11] CAKGGW*##DLDYW out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'GT' (2 nucleotides at position 10 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); acctctggaGTtcaccctttagtaaccattGggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16236 JY8QFUQ01BZ7HA No results +16237 JY8QFUQ01C6C9B productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1078 98.65 219/222 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 3 10 7 13 10.7.13 [2.17.38.11] CARHSSVTTFPIDYW in-frame - gtctctggtggctccatcagcagtagtggtttctactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaacctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagacatagttcggtgactaccttcccgatcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16238 JY8QFUQ01BX7AZ unknown (see comment) Homsap IGHV3-7*02 F 108 59.26 48/81 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16239 JY8QFUQ01A7OMB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16240 JY8QFUQ01BL1OC unknown (see comment) Homsap IGHV4-61*02 F (see comment) 566 78.07 146/187 nt 10 7 X 10.7.X [1.17.26.X] null + No rearrangement found Low V-REGION identity (78,07% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgactccattaccagtggtttttactactggaattggatcagacagcccgccgggaggggactggagtggatcggacgtgtctatattactgggagtgtcaactacagtccatccctcgaacacagagtcagtatatctctagacacgtccaagaggcaattcttcttgaggttggtctc +16241 JY8QFUQ01B8DVS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.37 197/218 nt Homsap IGHJ1*01 F (see comment) 133 74.0 37/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'ATTT' (4 nucleotides at position 101 to 104 in the user submitted sequence), (cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaGggggctggagtgggtctcaagtgtcagtagtagtactggttATTTtcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaacccaggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16242 JY8QFUQ01CUKGG productive Homsap IGHV3-7*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - ctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactttgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16243 JY8QFUQ01C0PJ7 No results +16244 JY8QFUQ01B4F8S unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 120 51.98 92/177 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found ctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccgaccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16245 JY8QFUQ01BRF2O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGSYLYSFDYW in-frame + cctctgggttcacctttgcccactttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtggtgatgattccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactcctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +16246 JY8QFUQ01A8LJ2 productive Homsap IGHV1-69*06 F, or Homsap IGHV1-69*14 F 840 88.32 189/214 nt Homsap IGHJ2*01 F 211 88.68 47/53 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [0.17.38.11] CATGADTGPNYWHFDLW in-frame - tggaggcaccttcagcaaccatgcgatcagctgggtgcgacaggcccctggacaagggcttgagtggatgggagggatcatccctcagtatggtgcagcaaactccgcactcaagttccacggcagaatcacgatgaccgcggacaaggccacaaacacagtctatatggaactgagcagcctgaaacctgacgacacggccgtctattactgtgcgactggtgcagacacgggcccaaattactggcacttcgatctctggggccgcggcacccgagtcacggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16247 JY8QFUQ01DFBH2 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'A' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggAagtgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggcccctggggctcctggtcaaggactanttcccccgaaccggtgacggtgtcgtggaactc +16248 JY8QFUQ01DNOGV No results +16249 JY8QFUQ01BCTAE productive (see comment) Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt 81.11 176/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggGggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc +16250 JY8QFUQ01A572P productive (see comment) Homsap IGHV3-30*01 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAGDLTGVPYYYDSSGLKYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctagattcaGccttcagtagctataatatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccaaccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16251 JY8QFUQ01DFNIJ No results +16252 JY8QFUQ01C3CF2 unproductive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPLGVG#FDNW out-of-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatatggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16253 JY8QFUQ01AJ72N No results +16254 JY8QFUQ01CKYUM unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 786 85.51 183/214 nt 85.05 182/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame - stop codons in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); ctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttaTacttaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16255 JY8QFUQ01B93IE No results +16256 JY8QFUQ01DP6MP unknown (see comment) Homsap IGHV3-7*01 F 1021 96.76 209/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +16257 JY8QFUQ01DV8ST No results +16258 JY8QFUQ01AL2ZX No results +16259 JY8QFUQ01BM7KL unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 677 80.19 170/212 nt 79.72 169/212 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD1-1*01 F 2 7 8 X 7.8.X [X.17.38.11] CATARTGPGTSIYLTAY## out-of-frame - Low V-REGION identity (80,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 77 of V-REGION: 'A' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); gccctggattcaacaaatatggcatgagttgggtccgtcaggctccgggggagggtctaaagtgggtctcaactattagtgatagtactggtcgcacatactactcagactctgttaagggccgcttcAaccgtctcctgggacacctccaaaaacacgttgtatctgcaaatgaaaaacctcagagtcgaagacacggccgtttattattgtgcgacagcccgcaccgggcctggaacctcgatttatctcacggcctattgggggccagggaacccgagtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +16260 JY8QFUQ01AVZ9C productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*06 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [0.17.38.11] CARGDGYNFGGLDYW in-frame - ctggattcaacttcataggttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactccgtgaggggccgatccatcatttccagagacgattctaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +16261 JY8QFUQ01DL5YY No results +16262 JY8QFUQ01DRFH2 No results +16263 JY8QFUQ01B771N No results +16264 JY8QFUQ01AX4YV unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF## out-of-frame - in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgCtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16265 JY8QFUQ01BJBUY No results +16266 JY8QFUQ01BX01L productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDWPSSGWSHFEAW in-frame + cctctggattcacctttgatgagcatgccatgcactgggtccggcaagttccggggaagggcctggagtgggtctctggtgttacttggaatagtggtgtcatagactatgcggactctgtgaagggccgattcaccatctccagagacaacgccaggaattccctgtatctacaaatgaacagtctgagaactgatgacacggccttctatttctgtgcaaaagattggccgagcagcggctggtcccattttgaggcttggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtnatcgcctgcctggtccagggcttcttcccccca +16267 JY8QFUQ01A80UX unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16268 JY8QFUQ01ADH46 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16269 JY8QFUQ01CMMJX productive Homsap IGHV3-7*01 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16270 JY8QFUQ01CWR2N No results +16271 JY8QFUQ01C5489 unproductive Homsap IGHV3-48*02 F 981 94.47 205/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CASIFWSGSPG##YYYGMDVW out-of-frame - ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgcgcctcgattttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16272 JY8QFUQ01A8FJO productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 993 96.26 206/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARPGVGASSFIDFW in-frame + tggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16273 JY8QFUQ01DGOV6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 823 95.53 171/179 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatg +16274 JY8QFUQ01CZLD3 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16275 JY8QFUQ01C7711 productive Homsap IGHV3-9*01 F 851 88.07 192/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + tctctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16276 JY8QFUQ01B6PCP productive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 966 94.86 203/214 nt 94.39 202/214 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 3 8 8 17 8.8.17 [0.17.38.11] CASLPGDLTQIQDGVFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggaggcaccttcgacagttatgttatcagctgggtgcgacaggCcccctggacaagggcttgagtggatgggcgggatcatccctatctttggttcggcaaagtatgcacagaagttccagggcagagtcaggattaccgcggacgaatccacgagcacggcctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgccagtcttcccggggatcttactcaaattcaagacggtgtttttgatatctggggccaggggacaatggtcagtgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +16277 JY8QFUQ01CU90A productive Homsap IGHV4-39*02 F 983 94.12 208/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.17.38.11] CARIVVRQFDQW in-frame + tctctggtgactccatttccagtactagttattactggggctgggtccgccagcccccagggaaggggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16278 JY8QFUQ01CNDLU unproductive Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDSPQP#DPW out-of-frame - cctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattcccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16279 JY8QFUQ01B57Z7 unproductive (see comment) Homsap IGHV3-66*02 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-9*01 F 2 8 7 X 8.7.X [2.17.38.11] CARFVWADD##FDIW out-of-frame - stop codons in CDR2-IMGT at codon 59 of V-REGION: 'CG' (2 nucleotides at position 92 to 93 in the user submitted sequence), (cause frameshift); agcctctggactcaccgtcaatgtcaattacatgagctgggtccgccaggctccagggaagggtctggagtgggtctccactatttatagcCGgggggtgccacttactacgcagactccgtgaggggccgattcaccatctccagagccaagtccgagaatacactgtatcttcagataagcggtctgagacttgaggacacggctgtgtattactgtgcgaggtttgtctgggccgatgatgccttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16280 JY8QFUQ01CU1CP productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +16281 JY8QFUQ01CBP12 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD2-2*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKDPQQLLAEVNWFDPW in-frame - ctctggattcacttttagaagttatgccatgagttgggtccgccaggctccagggaaggggctagagtgggtctcatctatcagtggtaatggtgataagacaaagtacgcagactccgtgaagggccggttcaccatctccagggacaattttaagaatacgttgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattattgtgcgaaagatcctcagcagctattggcagaggtaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16282 JY8QFUQ01DABDC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDTITMGGDVAPLFDYW in-frame + ctctggattcacctttagtaactatgacatgggctgggtccgccaggctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +16283 JY8QFUQ01APICN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccagccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgaccgggtgtcgtggaactc +16284 JY8QFUQ01CLT2P unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CTKRLSGRPLVESGAP#FFDDW out-of-frame + stop codons cctctggattcacctttagcgactatggcatgagttgggtccgccaggctccagggaagggactggagtgggtctcaagtattatcgctaatggtggtgacacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagatgaacagccttagaggcgaggacacggccgtatattattgtacgaaaagactatccggacggccgcttgttgaatcaggtgcgccccttctttgacgactgggaccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16285 JY8QFUQ01AZU0Q productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 705 81.31 174/214 nt 80.37 172/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,31% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 40 of V-REGION: 'C' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatgggCctgggtccgccaggctccgggCaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16286 JY8QFUQ01BKTFU No results +16287 JY8QFUQ01CKX10 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 269 59.69 117/196 nt 8 8 X 8.8.X [1.17.30.X] null + No rearrangement found Low V-REGION identity (59,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16288 JY8QFUQ01A8A1Y unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 826 87.79 187/213 nt 87.32 186/213 nt Homsap IGHJ6*02 F (see comment) 157 72.58 45/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.37.11] CAREKGSGPPN#GMDVW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 187 in the user submitted sequence), (cause frameshift) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagcccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccaacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16289 JY8QFUQ01BWBAO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +16290 JY8QFUQ01AUCPE productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16291 JY8QFUQ01BM9AS productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 773 83.04 186/224 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 13 8.10.13 [1.17.38.11] CATDSPTGYYAFDVW in-frame + Low V-REGION identity (83,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctgggttcgttttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +16292 JY8QFUQ01BH0QC unproductive Homsap IGHV3-9*02 F (see comment) 719 81.86 176/215 nt 80.0 172/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [0.17.38.11] CVKDKTKWGATLAIIP#FDFW out-of-frame - Low V-REGION identity (81,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 93 of V-REGION: 'A' (1 nucleotides at position 182 to 182 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 99 of V-REGION: 'G' (1 nucleotides at position 203 to 203 in the user submitted sequence), (cause frameshift); ctggattcaaccccgaaaaCtttagccatgcactgggtccgacaagttccagggaagggAcctgaagtgggtctcaggtataaattggaatggacgaaaaacaggatatgcggagtctgtgaggggccggttcaccatctccagagacaatgacaagaacgtcctttctttgcaaatgaccAattttggggactgaggacacGggccttctatttttgtgtgaaagataagacaaagtggggggccacactggccattatcccacgtttgacttctggggccagggagccctggttaccgtcgcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16293 JY8QFUQ01CICS6 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDNYGDY## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16294 JY8QFUQ01BDUCL productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 796 85.65 185/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + tctgggttaaccttcagtgaggatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagtcatttggaacaatggaaagacctttcactatgcagactccgtgaagggccgcttcgtcatctcccgagacaattccaagagcaccctatatttacaaatgaatagcctgagagtcgaggacacggctgtgtattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16295 JY8QFUQ01ADGSX productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1001 97.17 206/212 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 7 8 11 7.8.11 [X.17.38.11] CARGQQLRDFDYW in-frame - gatacaccttcaccagctactatttgcactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcgaggggacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16296 JY8QFUQ01B8QBH productive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttTgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16297 JY8QFUQ01BW7NT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARVFSGVAAPPDSW in-frame + ctctggatttcccttcaccagttactggatgcagtgggtccgccaagctccagggaaggggctggtctgggtctcacttagtaatagtgatgggagcactactacctacgcggacgccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatcttcaaatgaatcatctgagagtcgaggacaccgctgtatatttctgtgcgagagttttcagtggtgtcgctgctcccccggactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +16298 JY8QFUQ01DLIZU unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 905 90.83 198/218 nt 88.99 194/218 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD5-18*01 F 3 8 7 X 8.7.X [2.17.38.11] CARHSRLVRYFEF## out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'AGCAAGGTG' (9 nucleotides at position 22 to 30 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 69 to 70 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 31 of V-REGION: 6 nucleotides (from position 21 in the user submitted sequence), (do not cause frameshift) ctgtctctggtggctccatcaAGCAAGGTGgtagttatcactgggcctggatccgccagtccccagggGAaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtGccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16299 JY8QFUQ01C84M1 productive (see comment) Homsap IGHV3-72*01 F 870 88.64 195/220 nt 88.18 194/220 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-8*02 F 2 8 10 17 8.10.17 [1.17.37.11] CTRDTTDTGGQSFNGLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 97 of V-REGION: 3 nucleotides (from position 200 in the user submitted sequence), (do not cause frameshift) ctctggtttccccttcagtgaccacttcatggactgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaatcgaggacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctggggccaggggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16300 JY8QFUQ01AL1ZB unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CSKTPLGE#DYW out-of-frame - cctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtctcacgtattaatgaagatgggaggactacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacaccaagaacacactgtatctgcagatggacagtctgagagccgaggacacggctgtgtattactgttcaaagacacctttgggggagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttctt +16301 JY8QFUQ01AMJTH unknown (see comment) Homsap IGHV3-11*03 F, or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F 84 51.52 68/132 nt 8 10 X 8.10.X [2.17.9.X] null - No rearrangement found stop codons gcctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16302 JY8QFUQ01B0CR7 productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +16303 JY8QFUQ01BP1TQ productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatcgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcaggcg +16304 JY8QFUQ01AIVOZ productive Homsap IGHV3-30*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAGDLTGVPYYYDSSGLKYW in-frame + ctctagattcaccttcagtagctataatatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +16305 JY8QFUQ01ACYQ3 productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1034 95.98 215/224 nt 94.64 212/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 3 9 9 19 9.9.19 [1.16.37.11] CARGSSRGGRSDVNYYELDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 34 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 80 of V-REGION: 1 nucleotides (from position 152 in the user submitted sequence), (cause frameshift) tctccggggacagtgtctctaccacagagctgcttgaactggatcaggcagtccccatcgagaggcctcgagtggctgggaaggacatactacaggtccaagtggtattatgactatgcagtgtctgtccaaagtcgaataaccatcaaccagacacatccaagaaccagttctccctgcagctgaattctgtgactcccgaggacacggctgtgtattactgtgcaagagggtccagccgcggggggagatctgatgtgaactactatgagctggacttctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16306 JY8QFUQ01CWP59 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 815 86.24 188/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CAKDTITMAVTSLH#FDYW out-of-frame + cctctggattcacctttagtaactatgacatgggctgggtccgccaggctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +16307 JY8QFUQ01CESQP productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 3 8 8 16 8.8.16 [2.17.38.11] CARDHWAQHPAPHPFANW in-frame - gcctctggattcaccttcactagctatagtatgaactggctccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtggtactactgcatactacgcagactctgtgaggggccgattcaccatctccagagacaacgccaagaattcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagggaccattgggcgcagcacccggcaccccacccctttgccaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16308 JY8QFUQ01CFYC2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CARGHSYYVSSGPDY## out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); agcctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactgggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16309 JY8QFUQ01DGRK1 unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ2*01 F 112 67.92 36/53 nt Homsap IGHD1-14*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CARDADTTTTSWYFD#LG out-of-frame - in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); gtccggattcagcctcagtagctatgGgcatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagatatttgggctgctggaaataagatttattatgcagactccgtgaagggccgattcaccatctccagagacaggtccgagaatacggtgtatctgcaaatgaacaacctgagagccgaggacacgggtgtatatttctgtgcgagagatgccgataccactaccacatcatggtacttcgatctctggggggccgcggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccccagg +16310 JY8QFUQ01AZ6Y2 No results +16311 JY8QFUQ01DNBYK No results +16312 JY8QFUQ01BFTW4 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 932 92.2 201/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 16 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) gcctctggattcaccCTttggttattgatggcatgactgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16313 JY8QFUQ01BH8QF No results +16314 JY8QFUQ01B74OP productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16315 JY8QFUQ01B0XLC unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-30*01 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*04 F or Homsap IGHV3-30*05 F or Homsap IGHV3-30*07 F or Homsap IGHV3-30*09 F 101 95.45 21/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggattcaccttcattag +16316 JY8QFUQ01B0M6T productive Homsap IGHV1-2*02 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame + tggatatactttcaccgaccattatgtttactggatgcgacaggcccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16317 JY8QFUQ01C17DD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctacctggtccagggcttcttccccca +16318 JY8QFUQ01DPOHN No results +16319 JY8QFUQ01BHVC3 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 484 82.86 116/140 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (82,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag +16320 JY8QFUQ01BRA0B productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 890 90.7 195/215 nt 89.77 193/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [0.17.38.11] CARDRLTISALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); ctggattcacCctttaacaactacgccatgtcctgggtccgccaggctccagggaAaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16321 JY8QFUQ01ABWX4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKGIVGDTFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtaattatgccctgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggaatcagtagtagtggtgAgatccccaaactacgcagactccgtgaagggccggttcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaaagggatagtgggagacactttctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16322 JY8QFUQ01CO4L4 productive (see comment) Homsap IGHV4-59*03 F 908 91.63 197/215 nt 89.77 193/215 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'GA' (2 nucleotides at position 64 to 65 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 94 to 99 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagttTtctactggagtTtggatgaggcagcccccagggaggggGActgggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16323 JY8QFUQ01BPT7N productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARNTPAYWELSGDW in-frame + ctctggattcacctttaggagttattggatcagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaacccagatggaagtgagaaatactatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgcgcgaaatacaccggcgtattgggaactatcaggtgactggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16324 JY8QFUQ01CXM4M productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt 93.78 211/225 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 10 9 19 10.9.19 [1.16.38.11] CARASRRDRQSDRNYYELDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) ctccggggacagtgtctctagcaacagtgccacttggaactggatcaggcagtccccaacggaggccttgagtggctgggaaggacatcctacaggtccaaatggtatagtgattatgcggtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcaattgaactccgttagtcccgaggacacggctgtgtattactgtgcaagagcttccagacgcgatcgtcagtctgatcggaactactatgagctggacttctggggccagggaatcttggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16325 JY8QFUQ01CYGCX unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CTKDTFWER#DYW out-of-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgttttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16326 JY8QFUQ01CRRMD No results +16327 JY8QFUQ01BHW19 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGPHQYYFDYW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16328 JY8QFUQ01CWNBW No results +16329 JY8QFUQ01AHGS6 productive Homsap IGHV4-61*02 F 974 93.67 207/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame + tctctggtggctccatcagcagtggtaatcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctataaacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +16330 JY8QFUQ01CC0X3 No results +16331 JY8QFUQ01DE0TH unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16332 JY8QFUQ01BN76B productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-3*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARILTLFAVVTSSGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 75 of V-REGION: 'C' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); cctctggatttaccttcagtaattatgacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatcaccagtagtggtagttatgtctaccattcagactcaacgaagggcCcgattcaccatctccagagacaacgcccagaattcactatttctgcaaatgaacaacctgagacccgaggacacggctatatattactgtgcgaggatcctgacgctttttgcagtggttacctccagtgggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +16333 JY8QFUQ01DQANR unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggattttggaccgtactggggccaggaacctgtcaccgtctcctcagctccagccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16334 JY8QFUQ01BG3Q7 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame + in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtagttactggatgcactgggtccgccaaactccagGgggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +16335 JY8QFUQ01APOB5 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [1.17.38.11] CTRELRVAAARDGVDIW in-frame + ctctggattcaccgtcagtaccaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagtaatttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16336 JY8QFUQ01ATQIC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame - gcctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16337 JY8QFUQ01C5U2S No results +16338 JY8QFUQ01C9HMD productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16339 JY8QFUQ01CV1WW productive Homsap IGHV4-61*03 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 10 7 12 10.7.12 [1.17.38.11] CTRHPKSNVEGDSW in-frame + tccctggtggctccgtcagcagtggtagttatttctggagctggatccggcagcccccagggcaggggctggaatggatcggttatgtctataacaatgggaacaccaattacaacccttccctcaagagtcgagtcaccatttctatagacacgtccgagaatcacgtctccctgaagctggcctctgtgaccgctgcggacacggccgtgtactactgtacgaggcacccgaagtctaatgtagagggtgactcctggggccagggagccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16340 JY8QFUQ01BPSMC No results +16341 JY8QFUQ01A507Y No results +16342 JY8QFUQ01CHLRP No results +16343 JY8QFUQ01C431D unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARETLPPWCWG#FDNW out-of-frame + cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactccccccttggtgttgggggtttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactca +16344 JY8QFUQ01CHKLB productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CILLYYDSRGVFSTDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggcgtgggtctcacgtattaaaagtgatggcagtggcacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagagcacgctgtttctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtatactgctttactatgatagtagaggtgtcttttcaaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggctt +16345 JY8QFUQ01A9DAX productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +16346 JY8QFUQ01BLRJO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVPHQNIIYLDYW in-frame - ctctggattcgactttagcagcgcttccatggcctgggtccgccaggctccagggaaggggctggagtggatctcagctgtcagtggacgtggtgacaacaccttctacgcagcctccgtgaagggccggttcaccatctccagagaccattccaagaacacgctgtggcttcaaatgaacaacctgagagccgaagacacggccctatattactgtgcgagggaagtcccacatcaaaatataatctaccttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16347 JY8QFUQ01CDBPL unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16348 JY8QFUQ01DTV3M unproductive Homsap IGHV3-7*01 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARETLPLGVRG#FDNW out-of-frame + cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgggagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttaggggtttttcgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccgatcggtcttcccccatggcgccctgctccaggagcacctccgagagccanagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16349 JY8QFUQ01C9948 productive Homsap IGHV3-7*03 F 864 88.94 193/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctgtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16350 JY8QFUQ01DFBNU unproductive Homsap IGHV3-33*03 F 932 92.2 201/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGGSSGWFGRCGRL# out-of-frame + cgtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggcagcagtggctggtttggacgttgtggacgtctggggccaagggaccgacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16351 JY8QFUQ01AUK00 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1031 97.25 212/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found stop codons cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtaggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaagccctggctnaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +16352 JY8QFUQ01CVO2O productive (see comment) Homsap IGHV3-7*01 F 1021 97.22 210/216 nt 96.76 209/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.16.38.11] CAISSGFYSTGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 32 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtacctattggatggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16353 JY8QFUQ01CWGAA unproductive Homsap IGHV4-61*02 F 989 95.81 206/215 nt 94.88 204/215 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD2-21*01 F 3 8 7 X 8.7.X [1.17.38.11] CTNGGHYYGSEFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 35 of V-REGION: 'GCAGTG' (6 nucleotides at position 19 to 24 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); tctctggtgactccatcaGCAGTGgcagttactactggagctggattcggcagcccgccgggaagggactggagtggattgggcgtttgcataccagtgggggcCaccgactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggccgtgtattactgtactaatggcgggcattactatggttcggagtttgactactgggggccagggaaccctggtcaccgtctcctcaggcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +16354 JY8QFUQ01BJ4VI productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTRSSNSAYDYW in-frame + cctctggattcacgtttagtaacagttggatgggctgggcccgccaggctccagggaaggggctggagtgggtggccagcacaaaccaagatgcaagtgagaaaaagtatgtggactctgtgaggggccgattcaccatctcaagagacaacgccaagaactcactgtatttacaaatgaacagcctaagagccgaggacacggctttatatttctgtacgaggtccagtaacagcgcttatgactattggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcccagggcttnttcccccga +16355 JY8QFUQ01BC4JR productive (see comment) Homsap IGHV2-5*02 F, or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F 927 86.89 212/244 nt 86.48 211/244 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 3 10 7 11 10.7.11 [9.17.38.11] CAHFGPQEHFDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 95 of V-REGION: 'G' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); gaccctcaccctgacctgcgacttctctggattctcactcagcaccaatggaatgggtgtgggttggatccgccagcccccgggagaggccccagactggctcgctctcatttattgggatgatgataagcgataccggccatccctagagagtagactcaccatcaccaaggacatctccacaaaccaggtggtccttagaatgaccgacatgGggccctgcagacacagccacatatttctgtgcacactttggaccacaggagcacttcgacttttggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16356 JY8QFUQ01DJBV8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGRATGLVDWFDPW in-frame + ctctggattcaccttcaccaactacgccatgacctgggtccgccaggctccagggaaggggctggagtggatctcgactgttgtgggtggcggtggtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattcccagaacacgctgtatttgcaaatgtacaatttgggagccgaggacacggccctatattactgtgcgagaggtagagcgactggtctggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16357 JY8QFUQ01CF9B0 No results +16358 JY8QFUQ01B590E unknown (see comment) Homsap IGHV3-11*01 F (see comment) 756 83.41 181/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaccctcagtgactacagtatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatacatcagccgaagtggaagtaatgtggaaactgcggactctgtgaggggccgattcaccgcctccagggacaccgccaataattcactgtttctgcggatgaatagcctgacagtcgaggacacggccctctattactgtgcgagagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16359 JY8QFUQ01DOUJ6 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F (see comment) 776 84.58 181/214 nt 83.18 178/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 6 22 8.6.22 [2.16.38.11] CARVKTDYYDSSGSYLPLYFFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 44 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) gtctctggtgactccttcagaactcactactggagttggattcgaancccccgggggagganattggaaggattggcaatatatatatattgggaccaccaactacaaccCcctccctcaagagtcgagtcaccatgttagtggacacgtccaagaagcagttctccctgagactgagttctgtgaccgctgcggacacggccatgtattattgtgcgagggtcaagactgattattatgatagtagtggttcttacctgcccctgtatttctttgattactggggccagggaaccccggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16360 JY8QFUQ01DKP7D productive Homsap IGHV3-9*01 F 888 89.55 197/220 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD3-22*01 F 2 8 8 26 8.8.26 [2.17.38.11] CVKDHGVTYFYDSVGYVSGAYNYAMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cgtctctggattcacctttgatgattttggcatgcactgggtccggcaagttccagggaagggcccggagtgggtcgcaggtattagttggaatggtggacatatggactatgcggactctgtgaagggccgattcaccgtgtcccgagacaacgccgagaattccctgtatctgcaaatgaacagtctgacacctgaagacacggccctgtattactgtgtaaaagaccatggcgtcacttacttttatgacagtgttggttatgtctccggggcgtacaactacgcaatggacgtctggggccaggggacgacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +16361 JY8QFUQ01BUQBO productive (see comment) Homsap IGHV1-18*01 F (see comment) 759 84.11 180/214 nt 83.18 178/214 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 20 8.8.20 [0.17.38.11] CARDKKDYYDRRGYFGHYFDAW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 71 of V-REGION: 'TC' (2 nucleotides at position 118 to 119 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 77 of V-REGION: 'G' (1 nucleotides at position 134 to 134 in the user submitted sequence), (cause frameshift); tggttacaccattagtgactctggcttcagttgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcagcgctgagaatggtgacagaaatcgtgcaccgaagttTCccaagacagagtcaGccctgacgacagacacgtccacgaatacagcctatatggagatgaggggcctcacacctgacgactcggccatatattactgtgcgagagacaaaaaggattattatgatagaagaggttacttcgggcactactttgacgcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16362 JY8QFUQ01B8SPS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16363 JY8QFUQ01BS3U9 productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 91 to 96 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagttTtctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16364 JY8QFUQ01B8G46 productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16365 JY8QFUQ01A6DKS unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt 87.5 189/216 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGIVGASMQADWFHPW# out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); tctggattcgtctttggcgactatgcgatgagctgggtccggcaggctccagggagGggggctggagtgggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaAagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctgggggccagggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16366 JY8QFUQ01CJLYY unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16367 JY8QFUQ01CWGZQ productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.16.38.11] CARGEMTAEYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattgggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16368 JY8QFUQ01B6BSN unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 129 62.82 49/78 nt 8 X X 8.X.X [1.17.X.X] null - No rearrangement found tctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16369 JY8QFUQ01A8GWB productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 850 88.43 191/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [2.17.38.11] CTRGRSDAWELSDHW in-frame - gtcgacgatgggtcctgcagaaactgcttctggagttggatccgccagtccccagggaaggggctggagtggattggggaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagtcgagtcaccatatcattagacacgtccaacaaccaagtctccctgaggttgagctctgtgaccgccgcggacacggctgtgtattactgtacgcgagggcgatccgacgcgtgggaattatcggaccactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +16370 JY8QFUQ01ARO6U unproductive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*03 F 558 93.7 119/127 nt 92.91 118/127 nt Homsap IGHJ1*01 F (see comment) 107 67.31 35/52 nt Homsap IGHD6-19*01 F 2 8 X X 8.X.X [0.3.31.11] CARGPVSGWYTDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 35 in the user submitted sequence), (do not cause frameshift) tggatacaccttcaccgtctactatctattctggggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactgggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16371 JY8QFUQ01CWYZU productive Homsap IGHV3-7*03 F (see comment) 374 82.73 91/110 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 X X 19 X.X.19 [X.X.36.11] CARDRYSSDSSYYMPNWLDPW in-frame + Low V-REGION identity (82,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacgtttgggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16372 JY8QFUQ01BVW0E productive (see comment) Homsap IGHV3-13*01 F 971 94.88 204/215 nt 94.42 203/215 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacaCcatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcagccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgcaaccggtgcacggtgtcgtggaactc +16373 JY8QFUQ01CP6A0 productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1007 94.64 212/224 nt 93.75 210/224 nt Homsap IGHJ6*01 F (see comment) 180 76.19 48/63 nt Homsap IGHD4-11*01 ORF 3 8 10 18 8.10.18 [1.17.38.11] CVRHEGTPVSDVGGYGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtggctctgctatgcactgggtccgccaggtttccgggaaAagggctggagGtgggttggccgtattagaagcaaagcttacaattccgcgacagcatatgctgcgtcggtgaaaggcaggttcaccatctccagagatgattcaaagaacacggcgtatttggaaatgaacagtttgaagagggaggacacggccgtgtattactgtgtgagacatgaagggactccagtaagtgatgtaggtggatacggcatggacgtctggggtcaagggtccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +16374 JY8QFUQ01BDVTF productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - cctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgtcaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggagccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16375 JY8QFUQ01CLS6B No results +16376 JY8QFUQ01BCQEZ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16377 JY8QFUQ01BFHKG productive Homsap IGHV3-48*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARESTWEFTPDSW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcagtttcagtgactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagttctagtagtaccctatattatgcagactctgtgaagggccgattcaccgtctccagagacaatgacaagagttctctgtatctgcaaatgaccggcctgagagccgaagacacggcgacttattactgtgcgagagagtcgacgtgggaatttactcctgactcctggggcccggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16378 JY8QFUQ01ALEHP productive (see comment) Homsap IGHV3-33*03 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16379 JY8QFUQ01A0JCP unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 127 69.64 39/56 nt 8 X X 8.X.X [1.9.X.X] null + No rearrangement found ctctggattcacctttagtaaccattggatgaactgggtccagggcttcttcccca +16380 JY8QFUQ01BD5YC productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +16381 JY8QFUQ01ATPJW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CIMDLVGRADYW in-frame + ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +16382 JY8QFUQ01ALDGZ productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 800 86.05 185/215 nt 85.12 183/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'CC' (2 nucleotides at position 111 to 112 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttgggggAcaccgattacaaCCccctcccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgccctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +16383 JY8QFUQ01B2TGN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag +16384 JY8QFUQ01C0K37 No results +16385 JY8QFUQ01CYX7E productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 875 88.69 196/221 nt 87.78 194/221 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 2 10 7 16 10.7.16 [1.17.38.11] CTNDRSMAVRATHAFHIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'T' (1 nucleotides at position 145 to 145 in the user submitted sequence), (cause frameshift); tctctggtgactccattggtagcagtgcctactactGggggctgggtccgccagccccccgggaaggggctggagtggattggaagtatctattatggtggcaacacctactacaacccgtccctcaggagtcgagtcagcattTtccgcagacacgtccaagaaccagttctccctgcatctctactccgtgaccgccgcagacacggctctgtattactgtacgaatgaccgttcgatggccgttcgtgcaactcatgcttttcatatctggggcctagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16386 JY8QFUQ01CZ9PX productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16387 JY8QFUQ01CIIGJ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARAGYCNNGVCYSSYFDFW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccggggaaggggctggtgtgggtctcacgtatgaatagtgatggcagtgacataaggtacgcggactccgtgaggggccgattcaccatctccagagacaacaccaagaacacgctgtatctacaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagcgggatattgtaataatggtgtatgctactccagttactttgacttctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +16388 JY8QFUQ01CQCD8 productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKEEFDTGWTQPGDW in-frame + ctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16389 JY8QFUQ01DF1JA productive Homsap IGHV3-7*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CASGSGWTAEYW in-frame + tctctgaattcaccgttagcagtcattggatgaattgggtccgccaggctccagggaaggggctggaatgggtggccaacataaaacaagatgcaagtgagaaaaactatgtggactctgtgaagggccgattcaccatctcccgagacaacgccaagaattcactgtatctgcaaatgaacagcctgagactcgaggacacggctgtgtatttctgtgcgagtggcagtggctggacagctgaatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16390 JY8QFUQ01B0B79 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 798 88.61 179/202 nt 88.12 178/202 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 3 8 8 11 8.8.11 [1.17.33.11] CATEKPGNEFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 15 nucleotides (from position 155 in the user submitted sequence), (do not cause frameshift) gtctggattcaccctcagttcctatgtcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagtcattggatttaatggacgcagcgagtattatgcagactccgtgaagggccgattcaccatctccagagacaattctctgcaaatgaacaatctgagagtcgaggacacggctgtctattactgtgcgactgagaaacccggcaacgaatttgattactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccttgggctgcctggtcaaggactacttccccgaaccggtgacggtgtccgtggaactcag +16391 JY8QFUQ01BBN8Q productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt 85.32 186/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDYGDCRGGICYAEPLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'CCG' (3 nucleotides at position 21 to 23 in the user submitted sequence), (do not cause frameshift); cctctggattccagcctcgaCCGacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtatatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16392 JY8QFUQ01C1DCR unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD4-11*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CAKQTIFDYYYYG#LDVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcatgtttagtagctttcccatggcctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggttttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16393 JY8QFUQ01BIBVI No results +16394 JY8QFUQ01C5X9S unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 679 94.08 143/152 nt 8 8 X 8.8.X [1.17.16.X] null - No rearrangement found ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatg +16395 JY8QFUQ01AMCOH productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARDNARSYYSGVPDFW in-frame - gcgtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16396 JY8QFUQ01AW6G6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 995 95.41 208/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame + cctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +16397 JY8QFUQ01CDGWO No results +16398 JY8QFUQ01CCWMB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16399 JY8QFUQ01DDGIT unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 60 100.0 12/12 nt 2 X X 2.X.X [1.X.X.X] null + No rearrangement found cctctggattca +16400 JY8QFUQ01CK7QF unproductive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 848 87.33 193/221 nt 86.88 192/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 X 10.7.X [1.17.38.11] CARAWLDP#YFDSW out-of-frame + stop codons in FR3-IMGT at codon 103 of V-REGION: 'G' (1 nucleotides at position 218 to 218 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtggtaattactactggaactggatccgccaacccccagggaagggactggagtggattggatatatctactatgctggggccaccaacgtcgccccctccctcaagaaccgagtcaccataacgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccgtatattaGctgtgcgagggcgtggctggaccccctactttgactcctggggccagggaaatctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgctgcctggtccagggcttcttccccca +16401 JY8QFUQ01CC4MM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGRATGLVDWFDPW in-frame + cctctggattcaccttcaccaactacgccatgacctgggtccgccaggctccagggaaggggctggagtggatctcgactgttgtgggtggcggtggtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattcccagaacacgctgtatttgcaaatgtacaatttgggagccgaggacacggccctatattactgtgcgagaggtagagcgactggtctggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16402 JY8QFUQ01CE2OJ productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 781 84.98 181/213 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARGEECRSGSCYSVWFDPW in-frame + Low V-REGION identity (84,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggtgggtccttaagtgactcctactgggcctggatccgccagcccccagggaagggcctggagtacattggggagatcagtcatgatggtagaaccatgttcaattggtccctcaagagtcgactcaccatctcagtagacacgtccaagaatcaattctccctgagattgacctctgtgaccgccgcggacacggctgtttattactgcgcgagaggcgaggaatgtcggagtggaagttgctactccgtttggttcgacccctggggccagggagcccaagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16403 JY8QFUQ01BQ997 No results +16404 JY8QFUQ01CRDLW productive Homsap IGHV3-11*01 F (see comment) 789 84.55 186/220 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARYRGSYYDYGGVDVW in-frame - Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release aacctctggcttcagattccgtgactactacatgacgtgggtccgccaggctccagggaagggtcttgagtggctttcctccatcagcagcggtagtaataccatccactactcagactcggtgaggggccgcttcaccatctccagggacaacaccaggaactcagtggatctgcaaatgaatagtctgagagccgaagacacggccgtctattattgtgcgaggtacagaggcagttactacgactatggcggtgtggacgtctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16405 JY8QFUQ01A829Y unproductive Homsap IGHV3-64*02 F 953 93.95 202/215 nt Homsap IGHJ6*01 F (see comment) 88 61.02 36/59 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [0.17.38.11] CVTCGDYSYEY# out-of-frame - Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16406 JY8QFUQ01CFDZM productive Homsap IGHV3-48*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDRGGSAYPIFDYW in-frame - ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16407 JY8QFUQ01BKQXZ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcacctttagcagccatcccatgtactgggtccgccaagctccagggaaggGggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16408 JY8QFUQ01C9GN1 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16409 JY8QFUQ01DJZVC productive Homsap IGHV3-48*03 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARESWWSGFYGWYDPW in-frame + ctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16410 JY8QFUQ01COCK0 No results +16411 JY8QFUQ01A9JXU productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 905 90.83 198/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16412 JY8QFUQ01AQ5FG No results +16413 JY8QFUQ01CTBD0 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 876 90.19 193/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 164 to 164 in the user submitted sequence), (cause frameshift); aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgCtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16414 JY8QFUQ01ANWRU productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactcag +16415 JY8QFUQ01BFXW7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - tctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16416 JY8QFUQ01C8BJI No results +16417 JY8QFUQ01BXPO3 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) gcctcctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16418 JY8QFUQ01CI27V productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKLENSSGNEDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttaacgactatggcatgacttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactggtagtggtgataatgcctactacgcagacttcgtgaagggccgattcgccatctccagagacaattccaagaacatgttgtatttgcaaatgaacaacctgcgaggcgaggacacggccgtttattactgtgcgaaactggaaaatagcagtgggaatgaagactcctggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16419 JY8QFUQ01DFM1O productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'AG' (2 nucleotides at position 74 to 75 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggctgggagtgggtcAGtctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16420 JY8QFUQ01CFTLV productive Homsap IGHV1-2*02 F 903 91.59 196/214 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARDWGGKYAPLDNW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacatcttcaccggctactatttgcactgggtgcgacaggcccctggacaagggcttgagtggatgggatacatcgacccttacactggtgacacaaattatgcacagaggtttcagggcagggtctccatgaccagggacacgtccatcagtacagcctacatggaactgaacaggctgatgtctgacgacacggccatgttttactgtgcgagagattggggtgggaagtacgcaccgctagacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16421 JY8QFUQ01A2GTY No results +16422 JY8QFUQ01BW0NV No results +16423 JY8QFUQ01CUBGH productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 801 85.71 186/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16424 JY8QFUQ01AYGYZ No results +16425 JY8QFUQ01C0YRF No results +16426 JY8QFUQ01AO3TE No results +16427 JY8QFUQ01AARXS productive (see comment) Homsap IGHV3-33*03 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); cgtctggattGcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16428 JY8QFUQ01A2R0M productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*03 F or Homsap IGHV3-48*04 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + cctctggatttaccttcagtaatgattggatgatctgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16429 JY8QFUQ01BPZUU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgcctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16430 JY8QFUQ01BGNWL productive (see comment) Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 389 90.53 86/95 nt 89.47 85/95 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD5-18*01 F 3 X X 15 X.X.15 [X.X.31.11] CARSDEEYSYGDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'ACTAT' (5 nucleotides at position 22 to 26 in the user submitted sequence), (cause frameshift); cgtctggattcaccttcagtaACTATgagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatcggacgaggaatacagctatggggatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctgggcaccctcctccaaaagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16431 JY8QFUQ01CSQMJ productive (see comment) Homsap IGHV3-11*01 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16432 JY8QFUQ01CDRSX productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.17.38.11] CARGEMTAEYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtgttCaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16433 JY8QFUQ01DRD56 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16434 JY8QFUQ01DGSIU unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 874 89.04 195/219 nt 88.13 193/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.16.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) agtctctggattcaccttcagtagttatagtatgatctggGgtccgccaggctccagggaaggggctggagtgggtcgctcaattagtcataccgggggttccaaatattacggagactcactgaagggccgattcgccatctcaagagacaacgacaagaactcactgtatctgcaaatgaccagcctgagagccgaggacacggctgtctactactgtgcgagagccctaatagtagtgggctggtgccccctgtctattgggcagggaaaccctgggtcaccgtctccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16435 JY8QFUQ01C3U9E No results +16436 JY8QFUQ01B6HCR productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctgccagcctccaccaacgggcccatcggctcttccccctggcaccctcctcccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16437 JY8QFUQ01C5SYP productive (see comment) Homsap IGHV4-61*01 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgGggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16438 JY8QFUQ01C1DJZ unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 71 93.75 15/16 nt 4 X X 4.X.X [1.X.X.X] null + No rearrangement found tctggattcagtttca +16439 JY8QFUQ01B3P4D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16440 JY8QFUQ01BUXDW No results +16441 JY8QFUQ01CZQ30 No results +16442 JY8QFUQ01A9DAA productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 194 to 194 in the user submitted sequence), (cause frameshift); cctcgggactcatatttagcagctataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagagcCtgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16443 JY8QFUQ01A2Y6Z productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 7 8 16 7.8.16 [2.17.38.11] CAFSRALTGKWIDYLDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) gcctctggattcatctcagcaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16444 JY8QFUQ01CZ4QD productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 811 85.84 188/219 nt 84.93 186/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) ccctctgggattcaccttCagtacatgactggatgcactgggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16445 JY8QFUQ01B9LGG unknown (see comment) Homsap IGHV3-72*01 F 105 53.49 69/129 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons tctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +16446 JY8QFUQ01AA3KH unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgtccatagcatgaactggGgtccgccaggctccagggaaGggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaGggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16447 JY8QFUQ01BAKZQ productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 674 79.53 171/215 nt 78.6 169/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,53% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 71 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 75 of V-REGION: 'GGCT' (4 nucleotides at position 129 to 132 in the user submitted sequence), (cause frameshift); tctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccCgtgagggggcgGGCTtatcgaagtctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16448 JY8QFUQ01ACUYK productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - tctctggtggctccatcaacagtggtggttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16449 JY8QFUQ01DIM4C unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDYGDCRGGRCYAEPLDY## out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGcctcgccgacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16450 JY8QFUQ01B811Q No results +16451 JY8QFUQ01B94XC unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt 88.37 190/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW# out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 169 to 169 in the user submitted sequence), (cause frameshift); tctctggtggctCccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccCctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctgggggccaaggggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16452 JY8QFUQ01C2X6I unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 425 76.35 113/148 nt 8 7 X 8.7.X [1.17.16.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01C2X6I ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (76,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactacttccccgaaccggtgacggtgtcgtggaactcag +16453 JY8QFUQ01CPA03 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDISSGQHLPLGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattcagcttcagaagttataatatgaactgggtccgccaggctccagGggaaggggctggagtgggtcgcgtccattagtcctagtagtaatttcatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgagagatattagtagtggtcaacacctaccgttgggctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16454 JY8QFUQ01AHSTQ No results +16455 JY8QFUQ01BQ877 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 144 to 144 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccCagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcaggcctccaccaagggcccatcggtcttccccctggcgccctgctcccaggagcaccctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16456 JY8QFUQ01C4QOQ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-11*01 ORF 2 8 7 17 8.7.17 [1.17.38.11] CARVGRSVGYSDSGWFDPW in-frame + ctctggtggctccatgagtagttactactggaactggattcggcagcccccagggaagggactggagtggattgggtatatctattacactgggatcaccaactacaatccctccctcaagagtcgagtcaccatgtcaatagacacgtccaggaagcagttctccctgaccctgacctctgtgaccgctgcggacacggccgtctatttctgtgcgagagtcggccggagtgtgggctacagtgactctgggtggttcgacccctggggccagggaaccctggtcaccgtctcctcaccatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16457 JY8QFUQ01AFE1S productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.16.38.11] CARAIGRPFYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) gctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaagggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16458 JY8QFUQ01BBPWV productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16459 JY8QFUQ01AQKK1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD6-19*01 F 3 8 8 14 8.8.14 [1.17.38.11] CVKGGQWLVSNWFDPW in-frame + ctctggattcacctttagcagctatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtgctactggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacactctgtatcttcaaatgagcagtctgagagctgaggacacggctgtgtattactgtgtgaaaggggggcagtggctggtatccaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaa +16460 JY8QFUQ01C7RYA productive (see comment) Homsap IGHV3-30*01 F 951 92.73 204/220 nt 91.82 202/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [2.17.38.11] CPKTGPGHSSPFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); agcctctggattcaccttccgaagttatgatctgcactgggtccgccaggctccaggcaaGggggctagagtgggtggcatttaGtttcaaacgatggaagtgacacagactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaagacgctatatctgcaaatgaacagcctgagagttgaggacacggctgtgtattactgtccgaaaaccggccccggtcatagcagcccctttgactactggggccagggaaccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16461 JY8QFUQ01AZQ1P productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 779 84.4 184/218 nt 83.94 183/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CVKDYGNCAGGRCYSIPLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 64 of V-REGION: 'TTT' (3 nucleotides at position 99 to 101 in the user submitted sequence), (do not cause frameshift); cctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccgggaagggggctggagtgggtctcaggcatcactgatggtggtgggTTTttgacatactacgcagacgccgtgcagggccggtttattatttccagagacgattcccagaacacgatagatctgcaaatgaacaatttgagagccgacgacacggccatctattactgtgtgaaagattacggcaattgtgctggtggtcgctgctactcgattccccttgactattggggccggggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacaacaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16462 JY8QFUQ01A3IMT No results +16463 JY8QFUQ01DLAXE productive (see comment) Homsap IGHV4-61*02 F 857 87.78 194/221 nt 87.33 193/221 nt Homsap IGHJ4*03 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARERSASMGAARELDSW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'GGG' (3 nucleotides at position 99 to 101 in the user submitted sequence), (do not cause frameshift); tctctggtggccccatcggcagtggtgcctactactggacctggatccggcagcccgccgggaagggattggagtggctcgggcgtgtttatagtggtGGGgggatcatcaattacagtccctccctcaagagtcgaatcaccatgtcgatagacacgtccaagaaccagttctccctgaagttgacctctgtgaccgccgcagacacggccttatattactgtgcgagagaacgtagtgcctcgatgggcgctgcgagagaacttgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +16464 JY8QFUQ01APECD productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1081 99.54 218/219 nt 98.63 216/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [2.17.38.11] CARDFFIGGYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); gcctctggattcaccGttcagtagctatagcatgaactgggtccGgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16465 JY8QFUQ01DB2YL productive Homsap IGHV4-61*02 F 848 86.88 192/221 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD5-24*01 ORF 1 10 7 14 10.7.14 [1.17.38.11] CARGMATIKTVRFDPW in-frame + tctctggtggctccatgaggagtggaattaattcctggacatggatccggcagcccgccgggaagggactggagtggattgggcgtatctatatcaatggagacaccaactacaatccctccctcaagagtcgggccagcatatcaatggacacgtccaagaaccagttctccctgcacttgacctctgtgaccgccgcagattcggccgtctattattgcgcgagagggatggccacaataaaaacggtccgattcgacccctggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtggacggtgtcgtggaactcag +16466 JY8QFUQ01CSVHN productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 830 86.43 191/221 nt 85.97 190/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 12 10.7.12 [1.17.38.11] CARAGGWTPYFDSW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcaacagtggtaattactactggaactggatccgccaatccccagggaagggactggagtggattggatatatctactatgctggggccaccaacCtcgcccccctccctcaagaaccgagtcaccatatcgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccatatattactgtgcgagggccggtggctggaccccctactttgactcctggggccagggaaatctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16467 JY8QFUQ01BAXD9 productive Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame - Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16468 JY8QFUQ01DQ5GU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 896 90.37 197/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - cctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16469 JY8QFUQ01B5TMW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16470 JY8QFUQ01A98XI productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16471 JY8QFUQ01BNJBB productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.38.11] CARGRTVVTVIDYIDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); tctctgggggActccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccccctaagatgggaaccgtggtcgtcgcatgcctggctccagggcttcttcccccag +16472 JY8QFUQ01AEHFZ productive (see comment) Homsap IGHV3-72*01 F 858 87.44 195/223 nt 87.0 194/223 nt Homsap IGHJ6*02 F (see comment) 211 82.26 51/62 nt Homsap IGHD4-11*01 ORF 1 8 10 13 8.10.13 [1.17.38.11] CVRGLQSNYYGMDVR in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ttctggattcacctttggtgattatagtatgagttggttccgccaggctccagggaaggggctggagtgggttggccgtagtagagacaAaatttaacagttacagtacagaatatgccgcgtctgcgaagggcagattcaccatctcaagagatgaatcaaagaatttactgtatctgcaaatgaacagcctgagaagcgaggacacggccgtatattactgtgttagaggcctacagagtaattactacggtatggacgtcaggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16473 JY8QFUQ01B76BC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16474 JY8QFUQ01DDSJ6 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDPGWDKWKC#NWFDPW out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatcccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +16475 JY8QFUQ01DKM8F productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacctttagcCacttttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16476 JY8QFUQ01DPWM1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcaccagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16477 JY8QFUQ01BOMV5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccgag +16478 JY8QFUQ01CD2Z7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 824 86.7 189/218 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGFSAWGQDAFDIW in-frame - tctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16479 JY8QFUQ01CFS2I No results +16480 JY8QFUQ01CQGX0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame - cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16481 JY8QFUQ01AGVKW productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16482 JY8QFUQ01BCFIK productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +16483 JY8QFUQ01CS0TG productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactcag +16484 JY8QFUQ01AR2CD No results +16485 JY8QFUQ01CZKFT productive Homsap IGHV4-4*07 F (see comment) 542 73.11 155/212 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 2 8 7 14 8.7.14 [0.17.38.11] CARVRDAYTAGHFDSW in-frame - Low V-REGION identity (73,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggtgactctgtcactatgtcttattgggcctggatacgtcagcccgccgggggaggcctggagttaattggacgaacttctgccagtccaaaagttacctacaatccctccctcaggagtcgagccaccatattcgaagacacttcaaagaatcaacttatcttgaaattggcctctgtgaccgccgcggacacggccatctactactgtgcgagggtccgtgatgcctacaccgctggacactttgactcctggggcccgggaaccctggtcaccgtctcttcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccctca +16486 JY8QFUQ01AA617 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 289 65.16 101/155 nt 8 8 X 8.8.X [1.17.17.X] null + No rearrangement found Low V-REGION identity (65,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatatgaacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +16487 JY8QFUQ01BREFM productive Homsap IGHV3-9*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-21*02 F 3 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame - ctctggattcacttttgatgactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16488 JY8QFUQ01AS22B productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CAREKGSGPPTGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag +16489 JY8QFUQ01BO010 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CAKGGPCGGDCHTLLFDHW in-frame + gtctggattcgcatttagcagctatgccatgaactgggtccgtcagggtccagagaaggggctggagtgggtctcaggtattagtggtactgggggtagcacatacaacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacagcctgagaggcgaggacacggccgtatattactgtgcgaaaggaggcccttgtggtggtgactgccataccctgttgtttgaccactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaa +16490 JY8QFUQ01CVQ02 unknown (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 810 86.18 187/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtggcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +16491 JY8QFUQ01B3KMM No results +16492 JY8QFUQ01CE130 productive Homsap IGHV1-2*02 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame + tggatatactttcaccgaccattatgtttactggatgcgacaggcccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcatcgcctgcctggtccagggcttcttccccca +16493 JY8QFUQ01CIEX4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactcag +16494 JY8QFUQ01CVV6S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 698 80.28 175/218 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGLGLNAVYAFDVW in-frame - Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcgcttttggagattatgccatgaactgggtccgccaggccccagggaagggactggagtgggtctcaggtttgagcggtagaggcgtcagcaaatattatgcagactccgtgaggggccggttctccatttccagagacaactccgggagcgaggcagtccttcaaatgagcagcctgagagtcgaggacacggccacttactactgtgcgaggggcctagggcttaatgctgtctacgcatttgacgtctggggacaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16495 JY8QFUQ01BU0E2 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt +16496 JY8QFUQ01CTD2R productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +16497 JY8QFUQ01BR8J5 No results +16498 JY8QFUQ01AJ4OL No results +16499 JY8QFUQ01CN7J6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARAGYCNNGVCYSSYFDFW in-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccggggaaggggctggtgtgggtctcacgtatgaatagtgatggcagtgacataaggtacgcggactccgtgaggggccgattcaccatctccagagacaacaccaagaacacgctgtatctacaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagcgggatattgtaataatggtgtatgctactccagttactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16500 JY8QFUQ01DSJO1 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 84.62 187/221 nt Homsap IGHJ1*01 F 80 61.54 32/52 nt Homsap IGHD4-17*01 F 1 10 7 X 10.7.X [1.17.38.11] CARRWARQRLVMDYFDYW# out-of-frame - in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtactcattactattgGgggctggatccggcagGcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactgggggccaggggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16501 JY8QFUQ01DBY4W unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 353 86.17 81/94 nt 8 5 X 8.5.X [1.17.X.X] null - No rearrangement found ctctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc +16502 JY8QFUQ01CG389 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 856 88.13 193/219 nt 87.67 192/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-9*01 F 2 8 8 21 8.8.21 [2.17.38.11] CVREGIEYYEISTGQYYYDMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); gcctctggattcacAttttagcggctatggcatgagctgggtccgccaggctgcagggaaggggctggaatgggtctcatttattagtggtaagagcggcaacatatactatgcagaccccgtgaagggccggttcaccatctccagagacaactccaagaataggctcttcctgcagatgaacagcctgagagtcgaggacacggccaaatattactgtgtgagagagggcatagagtattacgaaatctcgactggacagtactactacgatatggacgtctggggccaggggaccacggtcaccgtcctctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16503 JY8QFUQ01C5I4I productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtGgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttgccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16504 JY8QFUQ01CK78N productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARVRGYYGGQYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctgggattcaccttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16505 JY8QFUQ01BYDI5 productive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD7-27*01 F 1 8 10 10 8.10.10 [1.17.38.11] CVRDPFSSRGHW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcatcctcagtgactaccacatggagtgggtccgccaggctccagggaaggggctggagtgggttggccgtagtagaaagaaagctaatagttacagtacagaatatgccgcgtctgtgaaaggcagattctccatttcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaatcgacgacacggccgtgtattattgtgtcagagaccccttctcaagtcggggccactggggccagggaaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +16506 JY8QFUQ01DEEHD productive (see comment) Homsap IGHV3-9*01 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggattcacctttcatgattataccatgcactGgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatcgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaaactcaggc +16507 JY8QFUQ01B14O3 unproductive (see comment) Homsap IGHV3-9*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CVKGHGRGSGTLVT#FDHW out-of-frame + stop codons Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaaggacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16508 JY8QFUQ01BQVL9 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1046 97.29 215/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16509 JY8QFUQ01CF6RJ productive (see comment) Homsap IGHV1-2*02 F 903 91.59 196/214 nt 91.12 195/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 1 8 8 22 8.8.22 [0.17.38.11] CARGGPERFSTSSVWYDPSLFDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); tggatacaccttcGaccgacaactatatgcattgggtgcgacaggtccctggacaagggcctgagtacatgggattcattaaccctaacagtggtggcacaaactctgcacagaagtttcagggcagggtcaccatgaccagggacacgtccgtcagcacagcctacctggaactgaacagactgagacctgacgacacggccgtatattactgtgcgagaggagggcccgaacgcttctcaacaagcagcgtctggtacgacccgagcctttttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16510 JY8QFUQ01DNZPN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16511 JY8QFUQ01C6JRR productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 915 92.89 196/211 nt 92.42 195/211 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [X.16.38.11] CARDTLEVVSNMDDAFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) tggatcaccgtcagtacctatagcctgaactgggtccgccaggctccaggaagggctggagtggatctcatccattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctgggcccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16512 JY8QFUQ01AZPSW productive (see comment) Homsap IGHV3-9*01 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [2.17.38.11] CVRQAYYHDSSAYFFSRYWYFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); gcctctggattcacttttgatgGactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacgccaagaagtccctgtttctgcaaattaaaagtctgagagttgaggacacggccttatattattgtgtgaggcaagcgtattaccatgatagcagtgcttacttcttctcccgctactggtacttcgatctctggggccgtggcaccccggtcactgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactactttcccgaaccggtgacggtgtcgtggaactcag +16513 JY8QFUQ01BG637 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame - ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16514 JY8QFUQ01C2CFT No results +16515 JY8QFUQ01BV968 unproductive (see comment) Homsap IGHV3-74*03 F (see comment) 311 73.95 88/119 nt 73.11 87/119 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 X 1 X X.1.X [X.X.38.11] CVRGTRGMER##DYW out-of-frame - stop codons Low V-REGION identity (73,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 79 of V-REGION: 'C' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); agcctctggattcattttcagtaactactggattcaccatctCcccgagacaacgccaagaacacgctgtatttgcaaatggacaatctcagaggcgacgacacggctctatattattgtgtaagagggacaaggggaatggagcgggattgactactggggtcagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16516 JY8QFUQ01C8VRV unproductive Homsap IGHV3-7*02 F 918 91.71 199/217 nt 90.78 197/217 nt Homsap IGHJ2*01 F 76 60.38 32/53 nt Homsap IGHD5-12*01 F 2 7 8 X 7.8.X [1.17.38.11] CARDQVTEDY## out-of-frame - in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtctgccaggctccagggaaagggctggagtgggtggcccacataaAaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtnttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16517 JY8QFUQ01CODF3 unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 709 85.13 166/195 nt 84.62 165/195 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) tgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16518 JY8QFUQ01C5139 unproductive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD1-1*01 F 1 10 7 X 10.7.X [1.17.38.11] CARVRARSNSHPGHSWFD#PW out-of-frame + tctctggtggctccatcagcagcagtagttactactcgacctggctccggcagcccgccggaaagggaccggagtggattgggcatatctatagtagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcggacacggccgtgtattactgtgcgagagtgagggcgcgcagtaatagtcaccccggccacagctggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16519 JY8QFUQ01AZQM7 No results +16520 JY8QFUQ01CNHLY No results +16521 JY8QFUQ01CRE6I productive Homsap IGHV2-5*02 F 1129 96.3 234/243 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD4-17*01 F 2 10 7 13 10.7.13 [9.17.38.11] CAHRSFYGDYVFDPW in-frame + accctcacgctgacctgcaacttctctgggttctcactcaccactaggggaatgggtgtgggatggatccgccagcccccaggaaaggccctggagtggcttgcactcatttattgggatgatgataagcgatacaggccatctctgacgagcaggctcaccatcaccaaggacacctccaaaaaccaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacagatcgttctacggcgactacgtcttcgacccctggggcccgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +16522 JY8QFUQ01AWGVW productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame - cgtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16523 JY8QFUQ01CTE4U No results +16524 JY8QFUQ01B81W4 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 950 93.12 203/218 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 7 10 9.7.10 [1.17.38.11] CASHGGKYFPQW in-frame + tctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggacaaatccatcatggtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +16525 JY8QFUQ01A8NED productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + cgtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcactctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgt +16526 JY8QFUQ01B5KCJ productive Homsap IGHV3-11*01 F (see comment) 788 84.86 185/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARYRGSYYDYGGVDVW in-frame + Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggcttcagattccgtgactactacatgacgtgggtccgccaggctccagggaagggtcttgagtggctttcctccatcagcagcggtagtaataccatccactactcagactcggtgaggggccgcttcaccatctccagggacaacaccaggaactcagtggatctgcaaatgaatagtctgagagccgaagacacggccgtctattattgtgcgaggtacagaggcagttactacgactatggcggtgtggacgtctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +16527 JY8QFUQ01ACVST No results +16528 JY8QFUQ01DICNL productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 866 88.24 195/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARQLSGDYASFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtgcctccatcaccagtggtactttttactgggcctggatccgccagcccccagggaaggggctggagtgggttggcaatatctattctagtggtgtcgcctattacaacccgtccctcaagagtcgagtcaccatgtccgtcgacacgtccaagaatgagttttccctgacactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16529 JY8QFUQ01DL1VC No results +16530 JY8QFUQ01A8YGX unknown (see comment) Homsap IGHV3-11*03 F, or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F 84 51.52 68/132 nt 8 10 X 8.10.X [2.17.9.X] null - No rearrangement found stop codons gcctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16531 JY8QFUQ01DN458 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 791 85.58 184/215 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [0.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16532 JY8QFUQ01DLL3K unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 123 72.92 35/48 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CANEVGYCSSR## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccagggaaggggctggagtgggtctcaactattcgtgcccgtggtgataggacacactacgcggactccgtgAaagggccgcttcaccatctctagagacaattcaaaggacaccctgtatttgcaaatgtacagcctgcgagtcgaggacacggccgtctattactgtgcgaacgaagtcgggtactgtagtagtcggggggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16533 JY8QFUQ01A1DJR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16534 JY8QFUQ01AC413 No results +16535 JY8QFUQ01A82JG productive (see comment) Homsap IGHV3-11*01 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-9*01 F 2 8 8 24 8.8.24 [1.17.38.11] CARDCHVDILTGYYRGSPPSCGLGVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 67 of V-REGION: 'T' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift); tctggattcaagctcggtgactactatatgaattggatccgccaggctccagggaaggggctggagtgggtttcatatattagtcttggtggtagccccacatattTatgcagactctgtgaagggccgattcaccatctccagggacaacgccaacaattcactatatctacagatgagtgccctgagagccgaggacacggccgtatattattgtgcgagagattgtcatgtcgatattttgaccggttattatcggggttcgcctccttcttgcggtctgggcgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +16536 JY8QFUQ01BYW9M unproductive (see comment) Homsap IGHV3-9*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKNVGV*MTVDGTGPI*LL# out-of-frame + stop codons ctctggattcacctttaataattatggcatgcactgggtccggcaagttccagggaagggcctggagtgggtctcaggtattagttggaatagcggaagtagagaatatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcagatgaacagtctgagagctgaggacacggctttgtattattgtgcaaaaaatgtcggggtataaatgacagtggatggtacgggccctatttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16537 JY8QFUQ01CWBOS productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +16538 JY8QFUQ01CKIZZ unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 803 85.07 188/221 nt 84.62 187/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 3 10 7 X 10.7.X [1.17.38.11] CARRWARQRLAE#YFDYW out-of-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtactcattactattggggctggatccggcagcCccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtctctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggctgagctactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca +16539 JY8QFUQ01AWUTM unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16540 JY8QFUQ01BFX0R unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 117 54.07 73/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons gctctggattcagatttagcagctatggcatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16541 JY8QFUQ01C8PQW productive Homsap IGHV3-7*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + ctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaaaaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcgaccgtctcctcagcatccccgaccagccccaagtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16542 JY8QFUQ01C4776 No results +16543 JY8QFUQ01BSZM3 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1007 94.64 212/224 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaaactc +16544 JY8QFUQ01A8PFM productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 795 85.98 184/214 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDHFDSW in-frame - Other possibilities: Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggatacaccttcaccgactacttcatacactggctgcgactggcccctggacaacgacttgagtggatgggatggatcaaccctaagaatggtgacacaaattatgcacggaactttcagggccgggtcaccatgacccgcgacacgtccgtcagaacagtatatgtggaggtgaacagcctgaaatctgacgacacagccatttattactgtgcgcgaggcttttatggtgaccactttgactcctggggccagggagccgtggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16545 JY8QFUQ01AG2V6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 147 56.82 75/132 nt 8 7 X 8.7.X [1.17.10.X] null + No rearrangement found ctctggattcaactttggcatctataccatggcctgggtccgccaggctcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +16546 JY8QFUQ01COULV productive Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16547 JY8QFUQ01DCGYU unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1105 100.0 222/222 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [2.17.38.11] CARSRTFYGSANYW# out-of-frame + gtctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16548 JY8QFUQ01AUNOE unproductive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-17*01 F 3 9 7 X 9.7.X [2.16.38.11] CARGEMTAEYYLDY## out-of-frame - in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 45 in the user submitted sequence), (cause frameshift) gtctctggtggctccatcagcagtgttaactggtggagttgggtcgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactaccttgattactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16549 JY8QFUQ01DF5I6 productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + tctacattcacgtttagtcgatattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16550 JY8QFUQ01C7L3B unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 904 91.2 197/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-23*01 ORF 3 8 7 X 8.7.X [2.17.38.11] CATGGHSGG#YW out-of-frame - in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 86 of V-REGION: 'A' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); gtctcgggtgactccatcactcctaactcctggagctggatccggcagAcccccagggaagggactggagtggattggttatatctattacagtggaatcaccaagcacaacccctccctcaagagtcgagtcgccatttcagtagacacgtccaagaaccaAgttttccctgaggctgagttctgtgaccgctgcggacacggccgtttatttctgtgcgacggggggtcactccggagggctactggggccagggaatcttagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16551 JY8QFUQ01CPAX9 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 121 69.81 37/53 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVVWSLWYFDL## out-of-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctgggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16552 JY8QFUQ01DC09Y unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt +16553 JY8QFUQ01CJM85 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - tgtctctggggactccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16554 JY8QFUQ01BSJ7Y productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 892 89.95 197/219 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame + gcctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctccatcagcatccccgaccacgccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16555 JY8QFUQ01C03JM productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 939 93.46 200/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-3*02 F 3 8 8 12 8.8.12 [0.17.38.11] CARGFSTYYGMDVW in-frame + cggatacaccttcacctattattttatacactgggtacgacaggcccctggacaagggcttgagtggatgggaataatcaaccctagtggtggtagcacaacctatgcacagaagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctacatggacctgagcagcctgaaatctgaggacacggccgtttattattgtgcgagaggctttagcacctactacggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16556 JY8QFUQ01AFMKM productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 7 11 8.7.11 [2.17.38.11] CARGGRGLRMTTG in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); cagtctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagagggggacgggggttaaggatgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16557 JY8QFUQ01AITKC No results +16558 JY8QFUQ01A865A unproductive (see comment) Homsap IGHV3-7*01 F 987 94.55 208/220 nt 94.09 207/220 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); gacctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca +16559 JY8QFUQ01ATZ1Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16560 JY8QFUQ01BJXU7 productive Homsap IGHV3-7*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16561 JY8QFUQ01BBLZF productive (see comment) Homsap IGHV3-48*01 F 1076 99.54 217/218 nt 98.62 215/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctaagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16562 JY8QFUQ01B8PFI unproductive Homsap IGHV3-30*01 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGVTKARYGLDV## out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggGggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctgggggccaagggaccacggtcatcgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16563 JY8QFUQ01DO20Y productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 715 96.73 148/153 nt 96.08 147/153 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 X 10 8.X.10 [2.14.27.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 53 of V-REGION: 66 nucleotides (from position 73 in the user submitted sequence), (do not cause frameshift) ccctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtggatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16564 JY8QFUQ01DQNCL unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGAPWRWCLLHLLF#DLW out-of-frame + in FR3-IMGT at codon 66 of V-REGION: 'T' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); cctctggattcacctttggcctctatgccatgaactgggtccgccagactccagggaaggggctggagtggctcgcaactattagtggtagtggaagtagatcatTtttacgcagactccctgaagggccggttcaccatctccagagacaattccaagggcacggtatacctggaaatgaccaccctgagagccgaggacacggccgtatattactgtgcgagagatggggctccgtggcgttggtgcttactacatctactattttcgacttatggggccagggaaccctggtcactgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +16565 JY8QFUQ01BZ7BR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16566 JY8QFUQ01BE1D5 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 937 92.24 202/219 nt 91.78 201/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [2.17.38.11] CARAYSGPGPYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 96 of V-REGION: 'T' (1 nucleotides at position 194 to 194 in the user submitted sequence), (cause frameshift); gcctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagTccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16567 JY8QFUQ01BN1RG productive Homsap IGHV1-8*01 F 831 87.85 188/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD3-16*02 F 3 8 8 15 8.8.15 [0.17.38.11] CARGRGTVWVQEGLDVW in-frame + tggatacaccttcacctcttatgatatccactgggtgcggcaggccactggacaagggctggagtggatgggccggatgagccccaatagcggtaacacaggctttgcacagaagttccacggcagagtcaccgtgaccaggaatctctccataaatacagcctacttggagctgggtagcctgaggtctgacgacacggccatttattactgtgcaaggggaaggggaactgtctgggtccaagagggtcttgatgtctggggccaagggacagtggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16568 JY8QFUQ01CF75G productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + ctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaanatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16569 JY8QFUQ01A0RX1 No results +16570 JY8QFUQ01DPEMX productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 94.17 210/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 71 of V-REGION: 'T' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgtTaaaaggcagattcaccatctcaagagaggattcaaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16571 JY8QFUQ01C0ZI3 productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 947 94.34 200/212 nt 93.4 198/212 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [0.16.37.11] CARDGGHSYGPSFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 45 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) tggatacaccttcaccaggtacattatgcactgggtgcgacaggccctggacaagggcttgagtggatgggaataatcaaccctagaggtgttagcagaagctacgcacagaagttccaggcagagtcaccatgaccaccgacacgtccacgagcacagtctatatggagctaaacagcctgagatctgaggacacggccgtttattactgtgcgagagatggagggcacagctatggaccctcctttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16572 JY8QFUQ01B0G9Q productive Homsap IGHV3-48*03 F 824 86.7 189/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame - ctctgggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16573 JY8QFUQ01CAIKC productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD1-1*01 F 1 8 8 18 8.8.18 [1.17.38.11] CAREPGRGYTPAMNWYFDLW in-frame + ctctggattcaccttcaggaactatgctatgcactgggtccgccaggctcctggcaaggggctagaatgggtggcttttatatcatatgatggaagtagtcaatactacgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacactttatctgcagatgaacagcccgagagctgaggacacggctgtgtattactgtgcgagagagcctgggaggggttatacacctgcaatgaactggtacttcgatctctggggccgcggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggccttcttcccccag +16574 JY8QFUQ01C0HVG unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacacagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggcccagggaaacctggtcaccgtctctcagcctccaccaagggcccatcggtcttcccctggcaccctctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16575 JY8QFUQ01CF81C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16576 JY8QFUQ01CYFDW productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 920 90.95 201/221 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 10 7 18 10.7.18 [1.17.38.11] CARSAYCGADCYSADYLQHW in-frame - tctctggtggctccgtcagcagtaggggttactactggaactggatccgccagttcccagggaagggcctggagtggattgggaacatcttttacagtgggggcacctacgacaacccgtccctcaggagtcgaatttctatatcattagacacgtctaagaaccaattctccctgaagttgacctctatgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16577 JY8QFUQ01BPCSK productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 920 90.95 201/221 nt 90.5 200/221 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAKRLQAVADDAFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); cagcctctggactcaacattggcaactatgacatgacctgggtccgccaggGctccagggaaggggctggagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgagcagcctgagagccgaagacacggccatatattactgtgcgaaaaggttgcaagcagtggctgatgatgcttttgatttctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16578 JY8QFUQ01B8407 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 987 94.55 208/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + ctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16579 JY8QFUQ01AODXR No results +16580 JY8QFUQ01DA3J2 No results +16581 JY8QFUQ01DCLJL unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 888 89.55 197/220 nt 87.27 192/220 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [2.17.38.11] CAEK*GGRRWL#WYFDFW out-of-frame - stop codons in CDR2-IMGT at codon 57 of V-REGION: 'ACT' (3 nucleotides at position 86 to 88 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 128 to 128 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'C' (1 nucleotides at position 149 to 149 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'G' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'AT' (2 nucleotides at position 216 to 217 in the user submitted sequence), (cause frameshift); agcctctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattACTaatggtggtggtggtgtcgtactctacgcagactccgtgAaagggccgattcaccatctcCcagagacaatGcccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgATttagtttctgtgcggaaaaataggggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16582 JY8QFUQ01ALIAX unproductive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1073 98.64 218/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 X 10.7.X [1.17.38.11] CARDRGP*QLVQNGI#DYW out-of-frame - stop codons tctctggtggctccatcaacagtggtggttactactggagttggatccgccagcacccagggaagggcctggagtggattgggtacatctattacagtgggagtacctactacaacccgtccctcaagagtcgagttaccatatcagtagacacgtctaagaaccagttctccctgaagctgagctctgtgactgccgcggacacggccgtgtattactgtgcgagagatcgggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16583 JY8QFUQ01B96JM unproductive Homsap IGHV3-72*01 F 971 92.86 208/224 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-3*01 F 1 8 10 X 8.10.X [1.17.38.11] CITSFGGRSLAY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16584 JY8QFUQ01CLIW9 unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F or Homsap IGHV1-69*01 F or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F 90 58.33 42/72 nt 56.94 41/72 nt X X X X.X.X [24.X.X.X] null - No rearrangement found in FR1-IMGT, from codon 7 of V-REGION: 3 nucleotides (from position 90 in the user submitted sequence), (do not cause frameshift) agttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgctctcggaggtgctcctggagcagggcgccagggggaagaccgatgggcccttggtggaggtgacgaagccaccagag +16585 JY8QFUQ01B1HSY productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 809 86.51 186/215 nt 85.12 183/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 7 7 9 7.7.9 [1.16.38.11] CTGLTYPDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 81 in the user submitted sequence), (cause frameshift) cgtctggatttaccttcagtaagttctgatgcattgggtccgccaagctccagggaagggctgacttgggtctcacgtataatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16586 JY8QFUQ01DIDT7 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaggGgaaggggctggGtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16587 JY8QFUQ01BTP79 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.37.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 105 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16588 JY8QFUQ01C7RDR productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 40 of V-REGION: 'T' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); ctccggattcagtttcagtacttataacatgaaTttgggtccgccaggctccagggaaggGggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16589 JY8QFUQ01CBQ9G productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F (see comment) 742 82.87 179/216 nt 82.41 178/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 2 8 8 18 8.8.18 [1.16.38.11] CATDLVTSTPGVLDDAYAFW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ctctggaatcacgttcaacagacatggcattcactgggtccgccaggccctggcaggggcctggagtgggtggctgttatgtcccgagacggaagtagacaatactatagagactccgtgaagggccgtttcgccatctccagggacacttccacgaacactgtgtatctgcaaatgaacagtctgagagttgacgactcggctctatatcgctgtgcgacagacttggtgacctccacaccgggagtcctcgatgatgcttatgccttttggggccaagggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16590 JY8QFUQ01COBZI No results +16591 JY8QFUQ01C6Z8M productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16592 JY8QFUQ01BFQT1 unknown (see comment) Homsap IGHV3-7*02 F 114 59.52 50/84 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found cctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16593 JY8QFUQ01A55U4 No results +16594 JY8QFUQ01DMG72 No results +16595 JY8QFUQ01A53U7 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - stop codons gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggctagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16596 JY8QFUQ01BHNR2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.74 200/218 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD3-3*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKQTIFDYYYYGLDVW in-frame + cctctggattcatgtttagtagctttcccatggcctgggtccgccaagctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16597 JY8QFUQ01BTGIG No results +16598 JY8QFUQ01A3GTG productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 674 79.53 171/215 nt 78.6 169/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,53% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'T' (1 nucleotides at position 192 to 192 in the user submitted sequence), (cause frameshift); tctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaAaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactcccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagcTcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +16599 JY8QFUQ01C4W5U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +16600 JY8QFUQ01AJMNA productive (see comment) Homsap IGHV2-5*02 F 1111 95.47 232/243 nt 95.06 231/243 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-17*01 F 3 10 7 13 10.7.13 [9.17.38.11] CAHFSVTTPYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift); gacctcacgctgacctgcaccttctctgggttctcactcaccactactggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcagtcaCttttttgggatgatgatgagcgccacagcccatctctgaggagaaggctcaccatcaccaaggacatctccaaaaaccaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacttttcggtgactaccccatatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16601 JY8QFUQ01CVI6U No results +16602 JY8QFUQ01APZBK No results +16603 JY8QFUQ01CU606 No results +16604 JY8QFUQ01C11P1 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt 85.12 183/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 7 X 8.7.X [1.17.38.11] CATLRGGY#FDYW out-of-frame + in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 77 of V-REGION: 'T' (1 nucleotides at position 135 to 135 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaggagttattattggagttggatccggcagcCccccaggaaagggactggagtggattggttatattaattatgttgggggAcaccgattacaaCcccctccctcaagagtcgagtcTcccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggctactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggcccttgggctgccctggtcaaggactacttcccccgaacccggctgacggtgtcgtggaactcag +16605 JY8QFUQ01C6MTP productive Homsap IGHV3-9*01 F 850 88.43 191/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame - tctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16606 JY8QFUQ01B5NY0 productive (see comment) Homsap IGHV2-5*02 F 1170 97.95 239/244 nt 97.54 238/244 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 2 10 7 11 10.7.11 [9.17.38.11] CAHRRIRFGFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttctctgggttctcactcagcactggtggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcactcatttattGgggatgatgataagcgctacagcccatctctgaagagcagactcaccatcaccaaggacacgtccaagaaccaggtggtcctcacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacaggaggatacgattcggctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaact +16607 JY8QFUQ01CJYLC unproductive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CVKDMVAGQGLLSR#LDHW out-of-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttggaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +16608 JY8QFUQ01CSXUP No results +16609 JY8QFUQ01A3ZD4 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 854 90.78 187/206 nt 90.29 186/206 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 9 nucleotides (from position 15 in the user submitted sequence), (do not cause frameshift) tctctggtgactctcacttctggagctggatccggcagcccccagggaagggcccggagtggattggttatgtctataacagtgggaccaccaactacaacccctccctcaggagtcgagtcaccatttctatcgacacgtccaagaagcagatctccctgaagttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16610 JY8QFUQ01COXC5 unknown (see comment) Homsap IGHV4-61*02 F 889 89.19 198/222 nt 88.74 197/222 nt 10 7 X 10.7.X [2.17.38.X] null + No rearrangement found in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gtctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgGggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttcggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +16611 JY8QFUQ01A2U2O No results +16612 JY8QFUQ01AVXM4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CANEVGYCSGG# out-of-frame + ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccgaaggtcttcccgctgagcctctgcagcacccacgccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +16613 JY8QFUQ01ADRBF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1075 100.0 216/216 nt 99.54 215/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.16.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16614 JY8QFUQ01BB1CN productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-48*03 F or Homsap IGHV3-48*04 F 820 86.3 189/219 nt 84.93 186/219 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [2.17.38.11] CARDSGSSDYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'T' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); cctgctggattcagttttagttcttatGggcatgaactgggtccgccaggctccagggggggggctggagtgggtctcattcattaacagtgttagtagTtacaaaatactatgtggacccagtgaGggggccgattcaccatctccagagacaacgccaagaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagatagcggctcgtccgactacactaggtacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctggggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +16615 JY8QFUQ01CIHG4 productive (see comment) Homsap IGHV4-34*13 F (see comment) 601 76.06 162/213 nt 75.12 160/213 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [2.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (76,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'AGG' (3 nucleotides at position 56 to 58 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'TGG' (3 nucleotides at position 80 to 82 in the user submitted sequence), (do not cause frameshift); gtctctgatggggtcgttcatgggttacctctggaattggatccgccagtcccccAGGggaagggggctggagtggattTGGgggaaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16616 JY8QFUQ01CA2FF unknown (see comment) Homsap IGHV3-74*03 F 118 54.69 70/128 nt 8 8 X 8.8.X [1.17.8.X] null - No rearrangement found cctctggattcaccttcagtagctactggatgcactgggtccgccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16617 JY8QFUQ01B2HM0 productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 175 75.81 47/62 nt Homsap IGHD3-16*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARAVGQRGYDGTDLW in-frame + ctctggattcatgttcagcagttattggatgagctgggtccgccaggatccagggaaggggctggagtgggtggccaatataaacgaagaaggaagtgagaaatattatgtggactctgggaagggccgattcaggatctccagagacaacgccaagaattccgtgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgcgagagcagtggggcagcgaggctacgacggtacagacctctggggccaagggaccacggtcatcgtctccacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16618 JY8QFUQ01DQDYT No results +16619 JY8QFUQ01AZA5L productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16620 JY8QFUQ01B8XA7 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 984 93.72 209/223 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 2 8 10 14 8.10.14 [1.17.38.11] CTTDPRYFWGSGFDYW in-frame + ctctggattccctttcagcaacacctacatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaaactgatggtgggacaatagaatacgctgcacccgtgaaaggcagattaaccatatcaagagacgattcaaaaaacacgctgtatctgcatatgagcagcctgaagatcgaggacacagccgtgtattactgtaccaccgatccccgttacttttgggggagcgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +16621 JY8QFUQ01C7YSJ productive (see comment) Homsap IGHV3-30*01 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtCgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +16622 JY8QFUQ01BZVSG No results +16623 JY8QFUQ01DBF0P productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16624 JY8QFUQ01C6C3L productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatcccctgaccagcccccaaggtcttccccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16625 JY8QFUQ01BFX42 unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1115 100.0 224/224 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFFGLL# out-of-frame + stop codons cttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16626 JY8QFUQ01CO4G6 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGHW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16627 JY8QFUQ01BJL9W No results +16628 JY8QFUQ01A2Y3S productive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtCgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16629 JY8QFUQ01CK0SW productive Homsap IGHV3-23*03 F (see comment) 894 91.12 195/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [1.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CK0SW ; 8 AA in Homsap_IGHV3-23*03) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttggttattatggcatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16630 JY8QFUQ01BYYSR productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYHFDYW in-frame + ctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16631 JY8QFUQ01AARBP productive Homsap IGHV3-72*01 F 1088 98.66 221/224 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-15*01 F 1 8 10 8 8.10.8 [1.17.38.11] CLRPPRYDPW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +16632 JY8QFUQ01ATVC1 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDNYGDYW# out-of-frame + ctctgaaatcaccttcagcgaccactacatgagctggatccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16633 JY8QFUQ01CMZOB unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 87 90.48 19/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattaaccctcagtga +16634 JY8QFUQ01AG2QF unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16635 JY8QFUQ01CJVE1 unproductive (see comment) Homsap IGHV3-7*01 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPPWCWG#FDNW out-of-frame + stop codons cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgagaacacggctatatattactgtgcgagagagacactccccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +16636 JY8QFUQ01CUPVA unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 8 X 8.8.X [1.17.38.11] CTTTLVWFGGV (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcgggggagttaggccaggaaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16637 JY8QFUQ01DH10O productive Homsap IGHV3-9*01 F 887 89.45 195/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.17.38.11] CTRSRVSIDLQPSYGMDVW in-frame + cctctggattcatctttgatgattttgccatgcactgggtccggcatgctccagggaggggcctggagtgggtctcaagtatcaactggaatggtgacgtcaaagcctatgcggactccgtgaagggccgattcaccgtctccagagacaacgccaagaactccctgtatctgcaaataaacgatctgagagcagaggacacggccttgttttactgcacaagaagtcgtgttagtatcgacttacagccctcctacggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16638 JY8QFUQ01C142N productive (see comment) Homsap IGHV3-72*01 F 921 90.58 202/223 nt 90.13 201/223 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-8*02 F 2 8 10 17 8.10.17 [1.17.38.11] CTRDTTDTGGQSFNGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggtttccCccttcagtgaccacttcatggactgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctggggccaggggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttctt +16639 JY8QFUQ01A1XO3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcGaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16640 JY8QFUQ01AEAEP productive Homsap IGHV3-74*03 F 904 91.2 197/216 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKVDSDGWHGTIDRW in-frame + tctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggatagcgatggctggcacggaacaatagaccgctggggccagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16641 JY8QFUQ01B58UQ productive Homsap IGHV3-7*03 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame - cctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16642 JY8QFUQ01DWOFO productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*15 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [2.16.38.11] CAKSPSQVGYYLDCW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 81 of V-REGION: 'A' (1 nucleotides at position 148 to 148 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagatactggatgcactgggtccgccagctcccggcaaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcaccatttccagagAaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16643 JY8QFUQ01CA5S5 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 795 85.98 184/214 nt 85.05 182/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.16.38.11] CARDSSNWSDAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'TG' (2 nucleotides at position 9 to 10 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) tctctggtTGggctccatgagtagtcactattggagttggatccggcaatcttcagggaaggactggagtggcttgactacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16644 JY8QFUQ01C8A3A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16645 JY8QFUQ01B1158 productive Homsap IGHV4-4*07 F 1061 99.53 214/215 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD4-11*01 ORF 2 8 7 13 8.7.13 [1.17.38.11] CARDFSNRGWYFDLW in-frame - tctctggtggctccatcagtagtttctactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16646 JY8QFUQ01CNI53 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 463 68.06 147/216 nt 67.59 146/216 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (68,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16647 JY8QFUQ01B859W No results +16648 JY8QFUQ01CXANC unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 926 90.62 203/224 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD6-6*01 F 2 8 10 X 8.10.X [1.17.38.11] CTSNSWLDR# out-of-frame - cctctggattctctttcagtaatgcctggatgaattgggtccgccaggctccagggaaggggctggaatgggttggccatattaaaagggaaattgatggtgggataacaaactacgctgcacccgtgaagggcagattctccatcgcaagagatgattcaaagaatatgatgtatttgcaaatgaacagcctgaacaccgaggacacaggcgtgtattactgtacctcaaattcgtggctcgaccgctgggccagggaacccccgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16649 JY8QFUQ01BLY5C No results +16650 JY8QFUQ01DF5WA No results +16651 JY8QFUQ01A1PLD productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctcaggattcaccttcagtaggtactggatgcactGgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16652 JY8QFUQ01B1OFN productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame - cgtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16653 JY8QFUQ01AG672 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame - ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16654 JY8QFUQ01A72DW productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame + ctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggccaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacgtgtcgtggaactca +16655 JY8QFUQ01BL2OD unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CARRGRCG*#YWYFDLW out-of-frame + stop codons tctctagtgactccatcagcagtactaattactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatgtatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgagacgggggagatgcggataactactggtacttcgatctctggggccgtggcaccctggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +16656 JY8QFUQ01CO3JF unproductive Homsap IGHV3-72*01 F 1093 98.67 222/225 nt 98.22 221/225 nt Homsap IGHJ6*04 F (see comment) 108 66.67 36/54 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [2.17.38.11] CLRPPRYDP## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift); gcctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcCaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16657 JY8QFUQ01B61QL unproductive Homsap IGHV3-13*01 F 881 90.23 194/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 7 X 8.7.X [1.17.38.11] CAGAEAGL#DYW out-of-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcgggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggcccctggggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16658 JY8QFUQ01AYPPE No results +16659 JY8QFUQ01DQZLQ productive Homsap IGHV3-7*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + cctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaacctcagg +16660 JY8QFUQ01CU9MI productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 18 8.8.18 [1.17.38.11] CSTGPSDLSRDYGDYGFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'CATGATGGAATG' (12 nucleotides at position 86 to 97 in the user submitted sequence), (do not cause frameshift); atctggattcaccttcagaaactatgccatgcattgggtccgccaggctccaggcaaggggctggagtgggtggcacttatatggCATGATGGAATGtttgatggaagaaatgaatattatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaatacggtgtatctgcaaatggacagcctgagagccgaggacacggctttgtattactgttcgacaggaccctcagaccttagtcgtgattacggtgactacggatttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16661 JY8QFUQ01BTPRA unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 734 91.86 158/172 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found ctctggagtcacctttagtgactattggatgagctggatccgccaggctccagggaaggggccggagtgggtggccaacatagagcaagatgggagtgagataaattatgtggactctgtgaagggccgattcaccatctccagagacaacaccgagaatgcactgtatctg +16662 JY8QFUQ01BZ30I productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 967 92.44 208/225 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [5.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ccgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16663 JY8QFUQ01CHZOM productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 833 87.16 190/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-6*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRSYSRTSEFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); cgtctggattcagtttcagtacctttggcatgagttggatccgccagacgccaggcAaaggggctggagtgggtgaAcagttatatggtcggatggaactCaaaaaaaattatgcagactccgtgaagggccgattcaccatctccagagacaatgtcaagaacacggtttatctgcagatgagcagcctgagagtcgaggacacgggcgtatattattgtgtgaggtcgtatagtaggacatctgagtttgactactggggcccgggaacccaagtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16664 JY8QFUQ01BJOFQ No results +16665 JY8QFUQ01COKQ0 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 807 85.45 188/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + ctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16666 JY8QFUQ01DI98R productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 870 88.64 195/220 nt 88.18 194/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKGIVGASMQADWFHPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'AG' (2 nucleotides at position 127 to 128 in the user submitted sequence), (cause frameshift); agcctctggattcgtctttggcgactatgcgatgagctgggtccggcaggctccagggagggggctggagtgggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaaAGgggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16667 JY8QFUQ01BKX5D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16668 JY8QFUQ01CNCWQ unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKKTL*FGDLFI#NFDYW out-of-frame + stop codons ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaacattataattcggggacttatttataacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16669 JY8QFUQ01B2RDP No results +16670 JY8QFUQ01CUGFD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-20*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGLTTMTGNGLEHW in-frame + tctctggattcacccttcgcagatatggcatggcgtgggtccgccaggctccggggaaggggctggagtgggtctcatcttctaacagtagtgatgaatccacatactatgcagactccgtgaagggccgcttcaccatttccagagaccattccaagaacacggtgtttttgcaaatgtacagcctgagagccgaagacacggccctctattactgtgcgagagggctaacaacaatgacagggaatggtcttgagcactggggccagggagccctggtcaccgtctcctcaccatccccggaccagccccaagggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtngtcgcatgcctcgtcccagggcttcttcccccag +16671 JY8QFUQ01CZ7WD No results +16672 JY8QFUQ01BI363 No results +16673 JY8QFUQ01CHHZW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16674 JY8QFUQ01BEQQ4 productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccttggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16675 JY8QFUQ01DDY03 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16676 JY8QFUQ01BHOMI unproductive Homsap IGHV3-11*01 F 936 92.63 201/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CTRDDRSVRGVTSDY## out-of-frame + ctctggattcaccttcagtgaccacttcatgagttggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggcagtggtagtataatatattacgcagactctgtgaggggccgattcaccatctccagggacaacgccaagaattccctctatctgcaaatggacagcctgagagacgaggacacggccgtgtatttttgtacgagagatgatcgctcggttcggggagtcacctcagactactgggggccagggaaccctggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16677 JY8QFUQ01CSKE5 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F (see comment) 660 78.97 169/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-10*01 F 2 8 8 21 8.8.21 [0.17.38.11] CARERRPGGYPNGYHHFYGMDVW in-frame + Low V-REGION identity (78,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgatacaattagtcgttatggcatgcactgggtccgccaggctccaggcaaggggctggagtggctggcaattatttcatatgatggaaataggatatatgttggggactccgtgaagggccgcttcaccgtttccagagacaacgccgggaggactctgtttctgcaaatgaacagtctgagaggtgatgacaccgccacatatttttgtgcgagagagcggcgtccgggtggctatccaaatggctaccaccatttttacggcatggacgtctggggccaagggaccagggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccttggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +16678 JY8QFUQ01DJBYG No results +16679 JY8QFUQ01BAGKP productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16680 JY8QFUQ01B2QTP productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 90 to 95 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16681 JY8QFUQ01AYWCC productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16682 JY8QFUQ01CHDMU No results +16683 JY8QFUQ01CADTF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16684 JY8QFUQ01BRQKS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16685 JY8QFUQ01A26WO unproductive Homsap IGHV3-7*01 F 1004 95.87 209/218 nt Homsap IGHJ3*01 F (see comment) 74 60.0 30/50 nt 8 8 X 8.8.X [1.17.38.11] CAISSGYYSTGY (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) gctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcnacgggctactgggccagggaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16686 JY8QFUQ01BQQG5 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*15 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F (see comment) 693 80.18 174/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-1*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRSPNHNWFDPW in-frame - Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaaattcaataattatgcaatgcactgggtccgccagtctccaagagcggggctgcaatgggtggcggctatatcgactgacggcaataaagaatatcatgcagactccgtgaagggccggctcaccctctccagagacaattcgaggagtacgctgtctctgcaattgcgcaacctgacagctgacgactcggctctgtattattgtgtcagatctcccaaccacaattggttcgacccctggggccagggagccctggtcactgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16687 JY8QFUQ01BUG1S productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16688 JY8QFUQ01AWK2B productive Homsap IGHV3-9*01 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame - cctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16689 JY8QFUQ01CB9HM productive Homsap IGHV3-7*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + tctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +16690 JY8QFUQ01BT86M productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARAGYCNNGVCYSSYFDFW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccggggaaggggctggtgtgggtctcacgtatgaatagtgatggcagtgacataaggtacgcggactccgtgaggggccgattcaccatctccagagacaacaccaagaacacgctgtatctacaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagcgggatattgtaataatggtgtatgctactccagttactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +16691 JY8QFUQ01DOSG1 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 960 93.18 205/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - stop codons agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgagtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16692 JY8QFUQ01CJDB1 productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16693 JY8QFUQ01DODI6 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.16.38.11] CARDSGSSDYTRYDAQDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) ctctggattcagttttagttcttatggcatgaactgggtccgccaggctccaggggggggctggagtgggtctcattcattaacagtgttagtagttacaaatactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaagaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagatagcggctcgtccgactacactaggtacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttgcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +16694 JY8QFUQ01AL2LZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16695 JY8QFUQ01AOZD0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgcctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16696 JY8QFUQ01BJP4R productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 904 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.16.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccagggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +16697 JY8QFUQ01CSZEK No results +16698 JY8QFUQ01A35F3 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16699 JY8QFUQ01A398K unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 894 89.24 199/223 nt 88.79 198/223 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 X 8.10.X [1.17.38.11] CTTAPKRNLCNG#YFAMDVW out-of-frame + stop codons Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 71 of V-REGION: 'CG' (2 nucleotides at position 125 to 126 in the user submitted sequence), (cause frameshift); ctctggatttactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcccccCGtgaaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagcccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgcccccgaaccggtgacggtgtcgtggaactc +16700 JY8QFUQ01CEUFV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 797 85.32 186/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctgaattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16701 JY8QFUQ01A6SR0 unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16702 JY8QFUQ01CW6WC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 856 88.13 193/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [2.17.38.11] CTREVGATDYW in-frame - cttctggagttcacctttagcagccatatgatgagttgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggagtaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16703 JY8QFUQ01CHC0L productive (see comment) Homsap IGHV1-24*01 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [0.17.38.11] CAIGAMATW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cgggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaAaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatcccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtgggtcatcgcctgcctggtccagggcttcttccccccag +16704 JY8QFUQ01A6ZA7 productive Homsap IGHV4-61*01 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame + tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16705 JY8QFUQ01BH8HX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16706 JY8QFUQ01ADJ2M productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16707 JY8QFUQ01DKUO1 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 953 93.95 202/215 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-2*01 F 2 8 7 12 8.7.12 [1.17.38.11] CAVSTTTWGWFDPW in-frame + tctatggtgggtccttcagtggttactactggagctggatccgccagcccccaggggaggggctgcagtggattggaagagtcaatcatagtggaagcaccagctacaacccgtccctcaagagtcgagtcaccatgtcactagacacgtccaagacccacttttccctgaagctgacctctgtgaccgccgcggacacggctgtgtattactgtgcggtgtctactaccacctgggggtggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct +16708 JY8QFUQ01CBMQQ No results +16709 JY8QFUQ01DWSKB productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 1 8 8 11 8.8.11 [0.17.38.11] CVRHTAMERGDYW in-frame + tggatatgactttatcaactactggatcggctgggtgcgccagatgcccgggagaggcctggaatggatgggaatcatctttcctgatgactctgatgccagatatagtccgtccttccagggccacgtcaccatctcagccgacaagtccacaagcaccgcctacctggagtggagcagcctgaaggcctcggacaccgccatctactactgtgtgagacatacagctatggagaggggtgactactggggcccgggaaccctggtcaccgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +16710 JY8QFUQ01APCCL productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 925 90.99 202/222 nt 90.54 201/222 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [2.17.38.11] CARGGSGGSYWNLIRDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); gtctctgatgactccgtcagcagtggtcgCttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16711 JY8QFUQ01COY09 productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 591 95.38 124/130 nt 94.62 123/130 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 X 11 8.X.11 [1.3.31.11] CAKGGGNGDLDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 38 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagtaaccattggatgaactggggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16712 JY8QFUQ01BY1LM No results +16713 JY8QFUQ01DPHKK unproductive Homsap IGHV4-61*02 F (see comment) 650 77.38 171/221 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-3*01 F 1 10 7 X 10.7.X [1.17.38.11] CARERDRSIGGAAELDS## out-of-frame + Low V-REGION identity (77,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccaatgtacccatcagtcgtggaggttactactggaattggatccggcaggccgccgggaaggggctggagtggcttggacgtgttgacagtaatggattcgtcaggtacaattcttccctcaaaagtcgcctttctatgtcactagacacgtccaagaatcagatctccctgatattgaggtctgtgatcgccgcagacacggccgtatatttctgtgcgagggagcgtgataggtcgatcggtggagcggcagaacttgactcctgggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16714 JY8QFUQ01CI4TN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [2.17.38.11] CARAYSGPGPYYFDYW in-frame - gcctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16715 JY8QFUQ01AHYKP productive (see comment) Homsap IGHV3-48*01 F 1000 95.43 209/219 nt 94.98 208/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); gcctctggtttcaccttcaggagctctggcatgaactGgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16716 JY8QFUQ01CWWU6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-14*01 ORF 3 8 8 9 8.8.9 [1.17.38.11] CANEEVPNDWW in-frame - tctctggattcacgtttagtagccatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggcatcagcataagcggagatagaacatattacgcagactccgtgaggggccgattcaccatctccagagacaattccaggaacactttgtatctacaaatgcacagcctgagagccgaagacacggccacatattactgtgcgaatgaggaggtcccgaatgactggtggggccagggaaccctggtcaccgtgtcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16717 JY8QFUQ01AOI9G productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16718 JY8QFUQ01BZKCF productive Homsap IGHV4-4*07 F 885 90.65 194/214 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD6-19*01 F 1 8 7 18 8.7.18 [1.17.38.11] CTKDVGPLGSDSYWDTLIIW in-frame + ctctggtgactccatcaatactttctactggagctgggtccggcagtccgccgggaagggactggagtggattgggcgtatctattccagtggggacaccaactacaacccctccctcaggagtcgagtcaccatgtcaatagacacgtccaggagtcagttctccctgaggctgacgtctgtgagcgccgcggacacggccatatattactgtacaaaagatgtagggccactgggcagtgactcgtactgggatactcttattatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagactgggaacggtggtcgtcgcatgcctggtccagggcttcttccccca +16719 JY8QFUQ01ARRQT productive (see comment) Homsap IGHV3-9*01 F 855 88.02 191/217 nt 87.1 189/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.16.38.11] CTRSRVSIDLQPSYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'A' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) gcctcggattcatctttgatgattttgccatgcactgggtccggcatgctccagggagggcctggagtgggtctcaagtatcaactggaatggtgacgtcaaagcctatgcggactccgtgaagggAccgattcaccgtctccagagacaacgccaagaactccctgtatctgcaaataaacgatctgagagcagaggacacggccttgttttactgcacaagaagtcgtgttagtatcgacttacagccctcctacggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16720 JY8QFUQ01DRAYY No results +16721 JY8QFUQ01CWK7E productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 967 92.44 208/225 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [5.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ccgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16722 JY8QFUQ01B7Z4F No results +16723 JY8QFUQ01BN0SJ No results +16724 JY8QFUQ01CB3UD unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 152 58.06 72/124 nt 8 6 X 8.6.X [1.17.9.X] null + No rearrangement found ctctggattcagcttcaatagttatactttgagttgggtccgccaggctccagggaaggggctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16725 JY8QFUQ01AGLFX unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRGLY*WCMLCR#DFW out-of-frame + stop codons cctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggcttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16726 JY8QFUQ01B5K0M No results +16727 JY8QFUQ01AIXHU productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16728 JY8QFUQ01AK0L3 No results +16729 JY8QFUQ01AONH0 No results +16730 JY8QFUQ01CE65C No results +16731 JY8QFUQ01A1DN4 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1081 99.54 218/219 nt 98.63 216/219 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [2.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); gcctctggattcaGccttcagtagttatagcatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggaaattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16732 JY8QFUQ01DFSFI productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 6 12 8.6.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 81 in the user submitted sequence), (cause frameshift) ttcgggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgtttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccgaaggtcttcccgctgagcctcgacagcacccccctaaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttcccc +16733 JY8QFUQ01BM4Y9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 833 87.16 190/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccaccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaac +16734 JY8QFUQ01C8VAK No results +16735 JY8QFUQ01CSMWR unproductive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [1.17.38.11] CAKLADTGEWSNRIFI#W out-of-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatctttatttctggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16736 JY8QFUQ01AD0EQ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [2.17.38.11] CGKTSFRCLRLTLTTG in-frame - gcctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtggaaagacctctttcaggtgtctacgacttactttgactactggggccgggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +16737 JY8QFUQ01AVK32 productive Homsap IGHV3-9*01 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + cctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattacttggaacagtggtaggataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgc +16738 JY8QFUQ01DFZ3Q unknown (see comment) Homsap IGHV4-61*04 F (see comment) 347 62.21 135/217 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (62,21% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16739 JY8QFUQ01DMUUW unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 973 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [2.17.38.11] CAGDLTGGSVLL*Q*WFK#YW out-of-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaTgcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactgggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16740 JY8QFUQ01AY47V productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 770 100.0 155/155 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 X 8 18 X.8.18 [X.5.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - tggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16741 JY8QFUQ01ASIFV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [2.17.38.11] CAKLGVAATTWNFFDYW in-frame - gcctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16742 JY8QFUQ01B6CI4 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 397 76.64 105/137 nt 75.91 104/137 nt 8 8 X 8.8.X [1.16.11.X] null - No rearrangement found Low V-REGION identity (76,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) cctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaagggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +16743 JY8QFUQ01DLYHZ productive (see comment) Homsap IGHV3-7*02 F 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaagGggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +16744 JY8QFUQ01BYUC2 No results +16745 JY8QFUQ01DEWGA unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 213 80.3 53/66 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found Low V-REGION identity (80,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgtctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggcttcttcccc +16746 JY8QFUQ01AFTH6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtcgacggtgtcgtggaactca +16747 JY8QFUQ01C151E productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 951 92.73 204/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - agcctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16748 JY8QFUQ01CLZES productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16749 JY8QFUQ01B8BL9 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARDSRHSASGSYSDYW in-frame - gcgtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16750 JY8QFUQ01A5HW4 productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaaccgaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaacggtgacggtgtcgtggaactca +16751 JY8QFUQ01BMJK2 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc +16752 JY8QFUQ01C5LMS productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16753 JY8QFUQ01BKOF3 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*02 F 3 8 8 19 8.8.19 [1.17.38.11] CARLPFIVVVTGAFLGHFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacatctttaccaattactggctcggctgggtgcgccagatgcccggcaaaggcctggagtggatggGggatcatctttcctgctgactctgatgcccgatacagcccgtccttccaaggccaggtcaccatctcaatcgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacgccgccatatattactgtgcgagactcccctttattgtggtggtgactggtgcgtttttgggacactttgactattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16754 JY8QFUQ01CZSU7 productive Homsap IGHV3-66*02 F 958 93.98 203/216 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD6-13*01 F 1 8 7 16 8.7.16 [2.17.38.11] CARDSPYSSGWSDGFDVW in-frame - gcctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatatcagtggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaagaacacggtgtatcttcagatgaacagtctgagagctgaggacacggctgtgtattactgtgcgagagatagtccatatagcagcggctggtctgatggctttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16755 JY8QFUQ01CRBJ3 productive (see comment) Homsap IGHV4-39*02 F 839 86.88 192/221 nt 85.97 190/221 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctctggtgaccccatcggcaacactgcttactcctgGgggctggatccgccagcCccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +16756 JY8QFUQ01AX1O9 unknown (see comment) Homsap IGHV3-11*01 F (see comment) 633 77.1 165/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AX1O9 ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (77,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16757 JY8QFUQ01DFJVB productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKEEFDTGWTQPGDW in-frame + ctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16758 JY8QFUQ01BDW17 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16759 JY8QFUQ01ATK2N productive Homsap IGHV3-66*02 F 858 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 12 8.7.12 [1.17.38.11] CARQTAPFGYFEDW in-frame + ctcggaattctccgtcagtgacagtcacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtagtgcatattatgcagactccgtgaggggccgattcaccatcgccagagacaaatctaagaacgtgttgtatcttcaaatgaacagtctgagacctgaggacacggctgtgtactactgtgcgagacagactgccccttttgggtactttgaggactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +16760 JY8QFUQ01C8T0U productive (see comment) Homsap IGHV3-7*01 F 869 88.99 194/218 nt 88.07 192/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'GA' (2 nucleotides at position 92 to 93 in the user submitted sequence), (cause frameshift); cctctaaattcaccTtttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaaagcagGAttgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16761 JY8QFUQ01B8FEW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16762 JY8QFUQ01CPXL5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame + Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16763 JY8QFUQ01BW489 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16764 JY8QFUQ01BJ3YF No results +16765 JY8QFUQ01AOGNY productive Homsap IGHV3-7*01 F 955 93.15 204/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - gcctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaagcggacatcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16766 JY8QFUQ01B2DU2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16767 JY8QFUQ01DOOXO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16768 JY8QFUQ01DAZL5 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame - cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16769 JY8QFUQ01COUPG No results +16770 JY8QFUQ01AW8M2 unproductive Homsap IGHV3-48*01 F 1075 99.54 215/216 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CASIFWSGSPG##YYYGMDVW out-of-frame - tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgattttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16771 JY8QFUQ01AAUZH productive Homsap IGHV4-59*03 F 890 90.7 195/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-23*01 ORF 3 8 7 9 8.7.9 [1.17.38.11] CARGVTPEGYW in-frame + tctcgggtgactccatcactcctaactcctggagctggatctggcagcccccagggaagggactggagtggattggttatatctattacagtggaatcaccaagcacaacccctccctcaagagtcgagtcgccatttcagtagacacgtccaagaaccaattttccctgaggctgagttctgtgaccgctgcggacacggccgtttatttctgtgcgaggggggtcactccggagggctactggggccagggaatcttagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +16772 JY8QFUQ01B52T3 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt 97.24 211/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16773 JY8QFUQ01CIUWJ No results +16774 JY8QFUQ01AMBVG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame + ctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagccacccagccaggatgggaagcntggtccatgcgctgcctgggtccaggcttcttcccc +16775 JY8QFUQ01B7S7G unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16776 JY8QFUQ01BI8UY productive Homsap IGHV3-7*01 F 1012 96.76 209/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + tctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16777 JY8QFUQ01CE1S4 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF## out-of-frame - tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16778 JY8QFUQ01BRK0D No results +16779 JY8QFUQ01CN7M5 productive Homsap IGHV3-11*04 F, or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F 972 92.48 209/226 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [4.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactcag +16780 JY8QFUQ01AUTF4 productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame + tctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16781 JY8QFUQ01CV876 productive (see comment) Homsap IGHV3-48*01 F (see comment) 754 84.04 179/213 nt 83.1 177/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 82 in the user submitted sequence), (do not cause frameshift) tctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtGgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16782 JY8QFUQ01C67G0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16783 JY8QFUQ01CIUCD productive Homsap IGHV3-66*02 F 912 92.06 197/214 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD6-25*01 F 1 8 7 11 8.7.11 [1.17.38.11] CARDGRGGDFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gtctggattctccgtcagtttcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcggttatttatgccgatggaagtacattctacgcagactccgtgaagggccgattcatcatctccagagacaattccaagaacacgctcaatcttcaaatgagcagcctgagagttgacgacacggctgtgtattactgtgcgagagatgggcgcggcggtgactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16784 JY8QFUQ01BGJ2O productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 788 84.86 185/218 nt 83.94 183/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.16.38.11] CVRDSDSSGYARYDSMDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gcctctggattcacgtttggcagccacgccatgagctggtccgccaggctccagggaagggactggagtgggtctcacacgtcaatCgggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16785 JY8QFUQ01AJ3Q0 unproductive Homsap IGHV3-21*04 F 995 95.41 208/218 nt 94.5 206/218 nt Homsap IGHJ5*01 F 129 72.55 37/51 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARAVSNQVDV## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); cctctggattcgccGttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagAttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgaatgcctggtccagggcttcttcccccca +16786 JY8QFUQ01CBCM8 productive Homsap IGHV3-48*01 F 860 88.53 193/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + tctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16787 JY8QFUQ01AT57K No results +16788 JY8QFUQ01BJ6RF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 820 86.3 189/219 nt 85.39 187/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [2.17.38.11] CVKDRDFLWGTYRLQLEHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); gcctctggattcagatttagcagctatgccaGtgagctgggtccgccagactccaggaaAaggggcttgaatgggtctcaggcatcaatgataacggtcgaagcataaactacgcgggctccgtgaagggccggttcaccatctccagagacaattccaagagcacgttgtatctgcagatggatagcctgagccccgaggactcgggcatatattattgtgtgaaagatcgtgatttcctttggggcacttatcgtcttcaacttgaacattggggccagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16789 JY8QFUQ01CJZTY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 143 to 143 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccCagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaaggggcccatcggtcttacccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16790 JY8QFUQ01B4T2J productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 10 7 13 10.7.13 [1.16.38.11] CVRHHYGGSLNFKYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) tctccggtgcctccatcagtagtaatagtcactactgggcctggatccgccagtcccagggaaggtcctggagtggattgggagtctctattatactgggagcaccctctacaacccgtccctcaagagtcgactcaccacatctgtggacacgtccaagaatctgttttccctgaacctgagtgctgtgaccgccgcagacacggctgtatattactgtgtgagacaccactacggtggttctctgaattttaagtactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16791 JY8QFUQ01ACU3I unproductive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 10 7 X 10.7.X [1.17.38.11] CATIVPSSVTALINDQGRFYFDH## out-of-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16792 JY8QFUQ01A7831 unproductive (see comment) Homsap IGHV1-8*01 F (see comment) 512 71.16 153/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.17.38.X] null - stop codons no junction found Low V-REGION identity (71,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctggatacaccttcaccaattatgatatcaactgggtacgacaggccagtggaaaagggcttgagtggatgggatggctgacccctaagagtagtaacacaggctctgtgcagaagttatagggcagagtcaccatgaccaggacttggagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16793 JY8QFUQ01BJOLZ unproductive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 X 9.7.X [1.17.38.11] CARGETDC##YYFDYW out-of-frame + stop codons tctctggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaactgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16794 JY8QFUQ01CJBTL productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt 98.16 213/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctatagcatgaactgggtccgccaggctccagggaagGgggctggagtgggtctcatccaAttagtagtagtagtagttacatatactacgcagactcagtgaaggGgccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16795 JY8QFUQ01DGWEK productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 927 90.27 204/226 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD5-24*01 ORF 3 8 10 17 8.10.17 [2.17.38.11] CSRGLGDGYNLGYHALDIW in-frame - agcttctggattcagttttggtgattattctatgatctggttccgccaggcaccggggaaggggctggagtgcgtaggtttcattagaagcagagcatatggtgggacaacacaatacgccgcgtctgtgaaagacagattcaccatctcaagagatgatcccaaaggcatcgcctatttgcaaatgagcagtctgaaagtcgacgacacaggcgtgtatttttgtagtcggggattaggcgatggctacaatctgggttatcatgcccttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16796 JY8QFUQ01AY3LZ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1053 98.62 214/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 1 8 7 9 8.7.9 [2.17.38.11] CARDTWPTSYW in-frame - tgtctctggtggctccatcagtagttactactggagctggatccggcagccccacgggaagggactggagtggattgggtatatctattacactgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagagatacctggccaacttcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16797 JY8QFUQ01CEZG1 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 945 93.09 202/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16798 JY8QFUQ01A5YDK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDRYPRSTAITAPDYW in-frame + ctctggattcatcttcacaagatatgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtcgcatctatcagtggtagtggtattacaacaaaatacgcagacgccgtgaagggccggtttaccatctccagagacagttccaggaacactctgttcctgcacatgagtggcctgagagccgaggacacggccgtgtattactgtgcgaaagatcgctaccctcggtcgacagctattacagcgcctgactactggggccagggaaccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +16799 JY8QFUQ01C2E1B No results +16800 JY8QFUQ01APNKV No results +16801 JY8QFUQ01CCL84 No results +16802 JY8QFUQ01CBM76 unproductive Homsap IGHV3-7*01 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CARREHNWDTVLALAAQ#DLW out-of-frame - in CDR2-IMGT at codon 57 of V-REGION: 'TAA' (3 nucleotides at position 83 to 85 in the user submitted sequence), (do not cause frameshift); ctctggattcagtatttataattattggatgaattgggtccgccaggctccagggagggggctggagtgggtggccagcattTAAaggcagacgggaactgagaagacgtttggggactctgtgaagggccgattctccatctccagagacaacgccaggaactcagtggatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcgaggagggaacacaactgggatactgtgctagccctagctgcccaactgacttgtggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16803 JY8QFUQ01CEJB8 unproductive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD1-1*01 F 1 10 7 X 10.7.X [1.17.38.11] CARVRARSNSSPRPQLVR#PW out-of-frame + tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccggaaagggaccggagtggattgggcatatctatagtagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcggacacggccgtgtattactgtgcgagagtgagggcgcgcagtaatagctcaccccggccacagctggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccggaaccggtgacggtgtcgtggcaactc +16804 JY8QFUQ01DDP0S No results +16805 JY8QFUQ01C0G1T unproductive Homsap IGHV3-9*02 F 896 90.37 197/218 nt Homsap IGHJ6*02 F (see comment) 96 63.16 36/57 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CGKDMRPGGMDV## out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctgggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16806 JY8QFUQ01BK7A2 unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 434 66.06 146/221 nt 64.71 143/221 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null + stop codons no junction found Low V-REGION identity (66,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 30 of V-REGION: 'CCTG' (4 nucleotides at position 15 to 18 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); tctcgggtgactccCCTGagtgccagtagtagTtttctactGggggctgggtccgccagcccccagggaagggactggagtggattgggactgtttattatagtgggagcgcccactacaatccgtccctcaagagtcgagtcgccatactgtgcgagaacttatacttatagaaatgcttttgacgtctggggccaggggacattggtcgctgtgtcttcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16807 JY8QFUQ01AYH1B unknown (see comment) Homsap IGHV3-74*03 F 135 55.56 75/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16808 JY8QFUQ01B2A34 No results +16809 JY8QFUQ01AVBM5 productive Homsap IGHV3-11*01 F 846 88.02 191/217 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CADIKLGDWCFDLW in-frame + ctctgaaatcaccttcagcgaccactacatgagctggatccgccaggctccaggaaaggggctggaatggatttcatatattagcaccagtggtaatatgatctattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaggtcgatgtatttgcagatgaacagtctgagagccgaggacacggccgtctatttctgtgccgatataaaactgggtgactggtgcttcgatctctggggccgtggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +16810 JY8QFUQ01BPA2X No results +16811 JY8QFUQ01APVTX No results +16812 JY8QFUQ01CSS61 unproductive Homsap IGHV3-72*01 F 1079 98.21 220/224 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYD#PG out-of-frame + cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccacgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16813 JY8QFUQ01AUKXZ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.17 200/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGYHGPFDS## out-of-frame + ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacacatactactcagactccgtgaggggccggttcaccatctccagagacaacgccaagaacacgatgtatctgcaaatgaacaccctgagagacgaggacacggccgtctatttctgcgcgaaaggttaccacggcccctttgactcttggggccggggcaaccctggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccanatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16814 JY8QFUQ01C7A52 productive (see comment) Homsap IGHV3-11*01 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ2*01 F (see comment) 211 88.68 47/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CADIRLGDWCFDIW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgaccactacatgagttggatccgccaggctccagggaaggggctggagtggatttcatatattagtactagtggtaatatgaGtttattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaactcactgtatctgcagatgaacagcctgagagccgaggacacggccgtctatttctgtgccgatataagactgggtgactggtgcttcgatatctggggccggggcaccctggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16815 JY8QFUQ01DOK15 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame - tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +16816 JY8QFUQ01CIXMG No results +16817 JY8QFUQ01ALCZK unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F 1047 99.07 212/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWGELSL#DYW out-of-frame - stop codons ctctggtgggtccttcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16818 JY8QFUQ01BIP93 unproductive Homsap IGHV3-21*04 F 962 94.42 203/215 nt Homsap IGHJ2*01 F (see comment) 85 62.26 33/53 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [0.17.38.11] CGKDMRPGGMD#LG out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctggattcaccttcaggacctataccacgaactgggtccgccaggctccagggaaggggctggagtgggtctcctccattagtagtagtagtagttacatatattacgcagactcagtgaagggccgcttcaccatctccagagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctgggggccagggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +16819 JY8QFUQ01B6JTT productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16820 JY8QFUQ01AZOI4 No results +16821 JY8QFUQ01CK28T productive Homsap IGHV1-3*01 F 966 94.86 203/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARWNNDLDYW in-frame + tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16822 JY8QFUQ01CJBIC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGRATGLVDWFDPW in-frame - cctctggattcaccttcaccaactacgccatgacctgggtccgccaggctccagggaaggggctggagtggatctcgactgttgtgggtggcggtggtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattcccagaacacgctgtatttgcaaatgtacaatttgggagccgaggacacggccctatattactgtgcgagaggtagagcgactggtctggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16823 JY8QFUQ01CNU48 unproductive Homsap IGHV3-48*02 F 871 90.14 192/213 nt 89.2 190/213 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [0.16.38.11] CARGQNGYKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'A' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift) tggattcaccttcgacagatacagtatgaactAgggtccgccaggctccaggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16824 JY8QFUQ01BG922 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16825 JY8QFUQ01AA9O7 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 7 21 8.7.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16826 JY8QFUQ01DELBD No results +16827 JY8QFUQ01DDFZD productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 796 85.25 185/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cnctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16828 JY8QFUQ01CE00X productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 984 93.72 209/223 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 2 8 10 16 8.10.16 [1.17.38.11] CAADGCPGGTCYHGFDMW in-frame + ctctggattcactttcagtaacgtctggatgcactgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgctggtggggcaacagaatacgctgcgcccgtgagaggcatattctccatctcaagagatgattcaaagaacacgttgtatctgcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtgccgcagatggttgtcctggtggtacctgctatcatggttttgatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +16829 JY8QFUQ01CIQNC unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16830 JY8QFUQ01CAD8M productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 866 88.24 195/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARQLSGDYASFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtgcctccatcaccagtggtactttttactgggcctggatccgccagcccccagggaaggggctggagtgggttggcaatatctattctagtggtgtcgcctattacaacccgtccctcaagagtcgagtcaccatgtccgtcgacacgtccaagaatgagttttccctgacactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16831 JY8QFUQ01B1XFK unproductive (see comment) Homsap IGHV3-7*01 F 1026 97.24 211/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgacaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16832 JY8QFUQ01CT5BN productive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARCPNYNIGTRGFDYW in-frame + tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16833 JY8QFUQ01CUQLX productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 888 91.47 193/211 nt 91.0 192/211 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [0.16.38.11] CTRELRLAAARDGVDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) ctgggttcaccgtcagtagcaagttcatgagctgggtccgccagggtccagggaagggctggagtgggtctcagttacttatcctgatggtactacacattatagagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16834 JY8QFUQ01BEBK3 productive Homsap IGHV3-9*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKDRGSSSKYYFDYW in-frame - ctctggattcacctttgatgattatgtcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggggaagtgctcatatacactatgcggactctgtgaaggaccggttcaccatctccagagacaacgccatgaactccctttatttgcaaatggacagtctgagagctgacgactcggccttgtattactgtgtaaaagatcggggtagcagttccaagtattactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16835 JY8QFUQ01BR29F No results +16836 JY8QFUQ01CTB5I productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16837 JY8QFUQ01C8J0R productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame - ctctgacgttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16838 JY8QFUQ01AYT1Z productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16839 JY8QFUQ01CIXAF No results +16840 JY8QFUQ01A3ZB9 productive Homsap IGHV1-3*01 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDGESLGGDYFDYW in-frame + tggatacaccttcagtaattatgctatacattggttgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctggcacgggtaacacaaaatattcacagaagttccagggcagagtcaccattaccagggacacagccgcgaccacagcctacatggaattgagcagcctgaaatctgaggacacggccgtgtattactgtgcgagagatggggagtcactgggaggcgactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +16841 JY8QFUQ01BXCLW unproductive Homsap IGHV3-23*03 F 905 90.83 198/218 nt 89.45 195/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 142 76.0 38/50 nt Homsap IGHD3-3*01 F 2 8 7 X 8.7.X [2.17.38.11] CTRELRLAAARDGVDIL# out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 102 in the user submitted sequence), (do not cause frameshift) cagcctctggattcccctttagcaactatgacatgagctgggtccgccagggtccagggaaAggggctggagtgggtcGtcagttacttatcctgatggtactacacattatagagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacattttgggggccaagggacaatggtcaccgtctcttcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16842 JY8QFUQ01CIUKG No results +16843 JY8QFUQ01DM9NE productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 881 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); gtttcggggttcaccgtcagtagcaagtacatnacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16844 JY8QFUQ01B4HAX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggc +16845 JY8QFUQ01DI195 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +16846 JY8QFUQ01AQ07I unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +16847 JY8QFUQ01DWTK3 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [0.16.38.11] CAKDQSCIVGPCGF*LL# out-of-frame - stop codons in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) ccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggtttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcaccctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcagg +16848 JY8QFUQ01C32DT productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaatcggtgacggtgtcgtggaactc +16849 JY8QFUQ01DQZLY No results +16850 JY8QFUQ01A9S5C unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*04 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*04 F (see comment) 302 65.03 106/163 nt 8 7 X 8.7.X [1.17.21.X] null + No rearrangement found Low V-REGION identity (65,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcaccatcactcactactccatggcctgggtccgccaggctccggggaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +16851 JY8QFUQ01BBJ5E productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 933 93.84 198/211 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 7 8 10 7.8.10 [X.17.38.11] CARGGLEPVDYW in-frame - attcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16852 JY8QFUQ01ALC3A unproductive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F (see comment) 617 74.89 170/227 nt 74.45 169/227 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-10*01 F 2 9 9 17 9.9.17 [2.17.38.11] CAREVTTRPPSYYKGLDVW in-frame - stop codons Low V-REGION identity (74,89% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 2 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) catctccggggacaatttgtagtaagacagctgcttgaattggatcgagacagccctcatcgggcggccttgaatggctgggaagggcatatttcaggtccaagtggtacattgaatatggagactctgtgaggggtcgcgttacgttcattggagacacactgacgaaccaattctccttgcacttggcctccgtgactcccgacgactcggctgtctatttctgtgcaagggaggtgaccacacggcccccctcctattataaaggtctggacgtctggggccaagggaccacagtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16853 JY8QFUQ01C1V1D productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +16854 JY8QFUQ01AVEH8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.16.38.11] CANASPRITGTYFYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) tctggattcacgtttggcagccacgccatgagctggtccgccaggctccagggaaggggctggagtacgtctcaattgttactgatagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16855 JY8QFUQ01A2XAO unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 93 52.27 69/132 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons cctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +16856 JY8QFUQ01BJ2WG unproductive (see comment) Homsap IGHV3-9*01 F 792 85.25 185/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 79 62.0 31/50 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CGRIAKPGLGALDL## out-of-frame + stop codons cgttggattcacttttaatgaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctggggcccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgctgcctggtccagggcttcttccccca +16857 JY8QFUQ01DP9CB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 904 91.2 197/216 nt Homsap IGHJ6*02 F (see comment) 256 90.32 56/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16858 JY8QFUQ01AHTPV productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 823 87.04 188/216 nt 85.19 184/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.16.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 73 in the user submitted sequence), (cause frameshift) tgtctctggggactccattagtggttactattggacgtggatccggcagAgccccagggaagggactggagtgattggaaatgtccattacacCtgggagtaCccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16859 JY8QFUQ01BGHJU productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 937 92.24 202/219 nt 91.78 201/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [3.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); caggtctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16860 JY8QFUQ01CNZ0D productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame - ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16861 JY8QFUQ01BWQ4Q productive (see comment) Homsap IGHV3-48*01 F (see comment) 764 84.19 181/215 nt 83.26 179/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaAaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16862 JY8QFUQ01AV57N productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16863 JY8QFUQ01DQJEG No results +16864 JY8QFUQ01BB2GZ productive (see comment) Homsap IGHV3-48*01 F 1065 100.0 214/214 nt 98.6 211/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.37.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 98 of V-REGION: 2 nucleotides (from position 198 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16865 JY8QFUQ01C9OHK productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 858 89.25 191/214 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame - ctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16866 JY8QFUQ01BOR1E productive (see comment) Homsap IGHV3-9*01 F 986 94.95 207/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [2.16.38.11] CAKSGTYSSSSGHFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gcctctggattcaactttaataaGttatgccatgcactggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccCctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16867 JY8QFUQ01ADSUP unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 140 53.04 96/181 nt 8 6 X 8.6.X [1.17.27.X] null + No rearrangement found cctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccgaccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16868 JY8QFUQ01CJ5K3 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 979 93.69 208/222 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 1 8 10 X 8.10.X [1.17.38.11] CTTDPRYFWGA#FDYW out-of-frame - tctggattccctttcagcaacacctacatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaaactgatggtgggacaatagaatacgctgcacccgtgaaaggcagattaaccatatcaagagacgattcaaaaaacacgctgtatctgcatatgagcagcctgaagatcgaggacacagccgtgtattactgtaccaccgatccccgttacttttggggagcgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16869 JY8QFUQ01BPA36 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.74 200/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKKYHYGSGTYLYYFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +16870 JY8QFUQ01BCCSR No results +16871 JY8QFUQ01B2TPF productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 2 8 7 17 8.7.17 [1.17.38.11] CAKNLRLGHSYFYNALDVW in-frame + ctctggtggcctcatcagtaattactattggacctggatccggcagcccccaggaaagggactggagtggattgggaacatctattacagtgggagcgccacctacaacccctccctcaagagtcgagtcaccatatcaatagactcgtccaagaaccagttctccctgaggctgaccgctgtgaccgctgcggacacggccgtgtattactgtgcgaaaaacttacgattgggtcacagttacttctacaacgctttggacgtatggggccaagggaccacggtcaccgtcgcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16872 JY8QFUQ01AX55P productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame - tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16873 JY8QFUQ01B8BPC productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatCggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16874 JY8QFUQ01A152R productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 915 90.91 200/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - agcctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +16875 JY8QFUQ01DMUBK productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16876 JY8QFUQ01ACD72 No results +16877 JY8QFUQ01C22P8 productive Homsap IGHV4-39*02 F 834 86.82 191/220 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16878 JY8QFUQ01B90UJ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 896 90.37 197/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) cctcctggattcaccCtttggttattatggcatgactgggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16879 JY8QFUQ01BACIJ No results +16880 JY8QFUQ01AG35D unproductive (see comment) Homsap IGHV3-7*01 F 975 95.33 204/214 nt 94.86 203/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [1.17.37.11] CAKGGW*R##LDYW out-of-frame + stop codons in FR3-IMGT, from codon 66 of V-REGION: 3 nucleotides (from position 104 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaatttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggctggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +16881 JY8QFUQ01CWCEK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 734 82.11 179/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*01 F 2 8 8 9 8.8.9 [1.17.38.11] CARGGTDFDYW in-frame + Low V-REGION identity (82,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggatttacatttagtgattataatatgaattgggtccgccgggctccagggaaggggctggaatatgtcgcaaccattacaactgggagtggtcaaatctactacagtgactcagtgaggggccgcttcaccatctctagagacgacgccaagaattcactttatctgcagatgaacaacctgagaggcgaggacacggctgtctatttttgtgcgagaggggggactgattttgactattggggccagggaaccctggtcaccgtctcctgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +16882 JY8QFUQ01AHEDS unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 786 85.51 183/214 nt 85.05 182/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 7 X 8.7.X [1.17.38.11] CATLRGGY#FDYW out-of-frame - stop codons in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); ctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttaTacttaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagaggggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16883 JY8QFUQ01CTA32 No results +16884 JY8QFUQ01CNHYC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16885 JY8QFUQ01B8T6Y productive Homsap IGHV3-9*01 F 891 90.32 196/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + ctctggattcacctttgatgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtattagttggaacagtggtaagatagactatgcggacgctgtgaagggccgattcatcacatccagagacaatgccaagaactccatctatttgcaaatgaacagtctgagagatgacgacacggccttctacttctgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16886 JY8QFUQ01A46ML unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16887 JY8QFUQ01CGLQI unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 156 78.43 40/51 nt 76.47 39/51 nt 7 X X 7.X.X [1.8.X.X] null + No rearrangement found in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) ctcagggttcgttttgagaaatacgccatgagttgggtccgccaggcccca +16888 JY8QFUQ01AP1AZ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16889 JY8QFUQ01DB81Q productive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARCPNYNIGTRGFDYW in-frame - tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16890 JY8QFUQ01BN2TK No results +16891 JY8QFUQ01CNQ0R unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ2*01 F 265 100.0 53/53 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CARRGRCG*#YWYFDLW out-of-frame + stop codons tctctagtgactccatcagcagtactaattactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatgtatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgagacgggggagatgcggataactactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +16892 JY8QFUQ01DFJ66 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 817 87.32 186/213 nt 86.85 185/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-6*01 F 1 8 7 12 8.7.12 [1.17.38.11] CVRSYSRTSEFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagtttcagtacctttggcatgagttggatccgccagacgccaggcaaggggctggagtgggtgacagttatatggtcggatggaactaaaaattatgcagactccgtgaagggccgattcaccatctccagagacaatgtcaagaacacggtttatctgcagatgagcagcctgagagtcgaggacacgggcgtatattattgtgtgaggtcgtatagtaggacatctgagtttgactactggggcccgggaacccaagtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16893 JY8QFUQ01C8F4Z productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 907 92.02 196/213 nt 91.55 195/213 nt Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD5-18*01 F 3 8 8 9 8.8.9 [X.17.38.11] CALGHNYGSAW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'CT' (2 nucleotides at position 18 to 19 in the user submitted sequence), (cause frameshift); ggattcacctttgatgaCTtttgggcatgagctgggtccgccaagttccagggaaggggctggagtgggtctgtggttatgcttggattggtggtgccccaacttatgcagcctctgtgaagggccgattcaccatctccagagacaacgccaagagctccctgtatctgcaaatgaacagtctgagagccgaagacacggccttgtatcactgtgcgctgggacacaattatggtagtgcctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16894 JY8QFUQ01B3TRM unproductive (see comment) Homsap IGHV4-39*03 F 933 91.78 201/219 nt 90.87 199/219 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD3-22*01 F 1 9 7 X 9.7.X [1.17.38.11] CARSITLTVVVMND##FDVW out-of-frame - stop codons in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 26 in the user submitted sequence), (cause frameshift) tctccggtggctccatcaacagtagaattattattggggctggatccgccagAcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgccttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16895 JY8QFUQ01AGSEB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ3*02 F 250 100.0 50/50 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKRLEGVADDAFDIW in-frame - cctctggattcacctttagcagctatgccatgggctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtgggagtggtcggagcacatactacgcagactccgtgaagggccggtacaccatctccagagacaattccaagaatacgatgtctgtgcaaatgagcagcctgagagtcgaggacacggccatatattattgtgtgaaaaggttggaaggagtggctgatgatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16896 JY8QFUQ01BBGFU productive Homsap IGHV3-7*01 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + gctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16897 JY8QFUQ01AA0HG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccggggaaggggctggtgtgggtctcacgtactaacacgggggggactaacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16898 JY8QFUQ01AR4WB productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16899 JY8QFUQ01A6RG8 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16900 JY8QFUQ01ASZ0M productive (see comment) Homsap IGHV4-59*03 F 786 85.51 183/214 nt 84.58 181/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.37.11] CARGRTVVTVVDYVDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 86 of V-REGION: 'C' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 109 in the user submitted sequence), (cause frameshift) tctctggtgactccattagtggttactattggacgtggatccgacagcgcccagggatgagcctggagtggattggacaagtccattacactgggagcaccaagtacagccctccctcaagagtcgagtcaccatttctgttgacatgtccaagaaccCaattcaccctcatcttgacctctgtggccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttgttgactacgttgacttttggggtcagggagtcctggtcaacgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +16901 JY8QFUQ01DSF94 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 185 89.13 41/46 nt 8 X X 8.X.X [1.5.X.X] null - No rearrangement found gctctggattcaccttcagtaagtatgccatgagctgggtccgcca +16902 JY8QFUQ01DI96K unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 941 92.66 202/218 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD1-1*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDTGQWKDFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggcccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +16903 JY8QFUQ01C5PFO productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 942 92.27 203/220 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [2.17.38.11] CARGMATAESW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) agcctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +16904 JY8QFUQ01AYM8A No results +16905 JY8QFUQ01AZDJV No results +16906 JY8QFUQ01DRJD4 No results +16907 JY8QFUQ01CHKNS No results +16908 JY8QFUQ01CZMUC No results +16909 JY8QFUQ01CA76U productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION tctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16910 JY8QFUQ01AZZIB unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 206 54.71 122/223 nt 54.26 121/223 nt 7 6 X 7.6.X [7.17.36.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (6 AA in JY8QFUQ01AZZIB ; 8 AA in Homsap_IGHV3-7*01), and low V-REGION identity (54,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift) aagatctcctgtgcagcctctggattcagtttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16911 JY8QFUQ01DB0RP No results +16912 JY8QFUQ01DDJMW productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 853 89.2 190/213 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16913 JY8QFUQ01B3LZM No results +16914 JY8QFUQ01BIQIL No results +16915 JY8QFUQ01CKBOH productive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cctctgggttcacctttaggagctattggatgaactgggtccgccaGggctccagggaaggGggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccc +16916 JY8QFUQ01ANO20 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 813 86.92 186/214 nt 85.51 183/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD1-26*01 F 3 8 7 11 8.7.11 [1.17.38.11] CATEREGGWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggGaacctatgccatgacgtgggtccgcctgactcctgggaAaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagactcagtgaagggccgattcaccgtctccagagacaacgccaagaaatcattgtatctacaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgacagagagggaaggtggctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16917 JY8QFUQ01BZZ70 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*05 F 948 91.93 205/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 1 8 10 X 8.10.X [1.17.38.11] CVVDIPEVGVG#FDYW out-of-frame + ctctggattctctttcacttatgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttgcccttattaaaagcaaaactagtggtgggacaacacactacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcagagaacacgttctatctacaaatgaatagactgaaaaccgaggacacagccgtgtattattgtgtcgtagatataccagaagttggtgtggggaatttgactactggggccagggagccctggtttccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +16918 JY8QFUQ01B4ZWU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSGSSDYTRYDAQDLW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcagtttggatacttatggcatgaactgggtccgccaggctccaggggaggggctggagtgggtctcattcattaatagtgttagcagttacaaatattatgtggactcagtgaggggccgattcaccatctccagagacaacgccaagaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagatagcggctcgtccgactacactaggtacgacgcccaggacctctggggccaagggaccgcggtcaccgtctcttcagcctccacaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactc +16919 JY8QFUQ01CQZKO unproductive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDQVTEDY# out-of-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactgggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16920 JY8QFUQ01BGV5H unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 981 94.06 206/219 nt 92.69 203/219 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.16.38.11] CARRGRCG*#YWYFDLW out-of-frame - stop codons in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) tctctagtgactccatcagcagtactaattactactggggctggatccgccagccccagggaaggggctgagtggattgggantaCtntatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgagacgggggagatgcggataactactggtacttcgatctctggggccgtggcaccctggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16921 JY8QFUQ01BF8CL productive Homsap IGHV4-61*02 F 1037 96.83 214/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARGPKYYYDSSGFEDLW in-frame + tctctggtggctccatcagcagtggtcgttactactggagctggatccggcagcccgccgggaagggactggaatggattgggcgtatttataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagctctccctgaagttgagttctgtgaccgccgcagacacggccgtatattactgtgcgagaggtcccaagtattactatgatagcagtggtttcgaagacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16922 JY8QFUQ01APSCL productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 1039 98.15 212/216 nt 97.69 211/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 7 12 8.7.12 [2.17.38.11] CAGSGRDPYGINVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); gcctctgggttcaccgtcagtagcaactacatgagctGgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16923 JY8QFUQ01CK36G productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +16924 JY8QFUQ01DW930 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 178 to 178 in the user submitted sequence), (cause frameshift); ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatTggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16925 JY8QFUQ01BEXOG productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 817 85.59 190/222 nt 85.14 189/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [2.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); gtctctggtgactccatcagtagtGactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16926 JY8QFUQ01ALFPF productive Homsap IGHV4-61*02 F 920 90.95 201/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 14 10.7.14 [1.17.38.11] CAREKVVIRPNWFDPW in-frame + tctctggtgactccatcaccagtggtaattattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggatcaccaactacaatccctccctcaagagtcgagtcaccatactattagacacgtccagcaaccggttctccctgaagctcagctctgtgaccgccgcagacacggccgtgtattactgtgcgagagaaaaagtagtgatccgtcccaattggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16927 JY8QFUQ01BA8EB No results +16928 JY8QFUQ01B6PBL unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRGGSQWGLQVG#FDYW out-of-frame - stop codons cctctggattcaccttcagtggttactggatgcactgggtccgccaagctccaggaaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgacgacacggctgtttactactgtgtgagaggggggagtcagtggggccttcaggtgggggtttgactactggggccagggaaccctggccaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacgattccccgaagccggtaacggtgtcgtggaactcagg +16929 JY8QFUQ01ASK4D productive Homsap IGHV4-61*02 F 879 88.69 196/221 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.38.11] CARDFGGSYNLVPTG in-frame - tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttntgtgcgagagattttggaggttcctacaatttagtgcctactggggccaggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16930 JY8QFUQ01A82IN productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F 845 88.37 190/215 nt 87.91 189/215 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD4-17*01 F 2 8 7 18 8.7.18 [1.17.38.11] CASLVTINDNGDYTWAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tggatggtgggtccttcagtaataagtattggagttggattcgccagtTccccagggaaggggctagagtggattggagaaatcaaccaaagtggaagcaccaactacaatccgtccctcatgagtcgagtcaccatctccatagacacgtccaagatgcagttctccctgaagttgacctctgtgaccgccgcggacacggctgtctattattgtgcgagtttagtgaccattaatgacaacggtgactacacgtgggcttttgatgtctgggcccaagggacaatggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +16931 JY8QFUQ01B71VU productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 940 93.06 201/216 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [2.17.38.11] CARAPRTATLLDPW in-frame - gtctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +16932 JY8QFUQ01CR93B productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16933 JY8QFUQ01CM1WR No results +16934 JY8QFUQ01DPGK3 productive (see comment) Homsap IGHV3-7*01 F 1040 97.71 213/218 nt 96.79 211/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cctctggattcaggtttagcatctattgGgatgagctgggtccgccaggctccagggaaggGggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +16935 JY8QFUQ01CHPNW unknown (see comment) Homsap IGHV3-49*02 F, or Homsap IGHV3-49*04 F 92 50.0 92/184 nt 49.46 91/184 nt 8 7 X 8.7.X [1.16.28.X] null + No rearrangement found in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 63 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagttctcacactatgaactgggtccggcaggctccagggaaggggccgagtgggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16936 JY8QFUQ01C0J7S productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 863 89.3 192/215 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame + cctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16937 JY8QFUQ01AVP0N productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 912 92.06 197/214 nt 91.12 195/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARRDVGSHAFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); tggatacaAtttttaactacgactggatcgGgctgggtgcgccagatgcccgggaaaggcctggagtggatggggatggtctatgttggtgactctgatgctagatacagcccgtcctccgaaggccaggtcaccatctcagccgacaaggccatcagtaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggatgtgggttcacatgctttcgatctgtggggccaagggacaatggtcaccgtttcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16938 JY8QFUQ01CQHI2 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.37.11] CAKDGARGGGSCFNSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 176 in the user submitted sequence), (cause frameshift) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16939 JY8QFUQ01BGJ69 productive (see comment) Homsap IGHV3-7*01 F 977 94.5 206/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); tctctggattcaccGtttagtagggtttggatgacctgggtccgccagGggtccagggaaGggggctggagtgggtggccaacataaAagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +16940 JY8QFUQ01BEBWZ No results +16941 JY8QFUQ01DNHLW unknown (see comment) Homsap IGHV3-11*01 F (see comment) 628 77.0 164/213 nt 76.53 163/213 nt 8 7 X 8.7.X [1.17.38.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DNHLW ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (77,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); tctggattcagcttcagtgactactacatgagttgggtccgccaggGctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16942 JY8QFUQ01BEJ4M No results +16943 JY8QFUQ01CHMQ3 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 962 94.42 203/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [0.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16944 JY8QFUQ01DMX02 productive Homsap IGHV3-21*04 F (see comment) 662 78.44 171/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVRLFTSDGVRGDYW in-frame + Low V-REGION identity (78,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctccggtttcatcttcagtcacttcagcatgaactgggtccgccaggctccaggaaagggcctggagtggatcgccgacatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcgacgatacggccacctattattgtgtgaggctcttcaccagcgatggagtgagaggcgactactggggccagggcgcccgggttctcgtctccgcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16945 JY8QFUQ01DKEJS productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'ACCCCCA' (7 nucleotides at position 81 to 87 in the user submitted sequence), (cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcaACCCCCAaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16946 JY8QFUQ01BZ0PJ unknown (see comment) Homsap IGHV3-69-1*02 P 1029 98.13 210/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - Rearranged sequence but no junction found however the closest V is a pseudogene The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctagattcaccttcagtgagtactacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattaggagtagtagtaccatatactacgcagactctatgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtttattactgtgcgagagacgcaatgaattcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16947 JY8QFUQ01C5PN0 productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16948 JY8QFUQ01AEV7X productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16949 JY8QFUQ01CV10S unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 814 97.65 166/170 nt 8 7 X 8.7.X [1.17.23.X] null + No rearrangement found ctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttc +16950 JY8QFUQ01C3YA5 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*02 F or Homsap IGHV3-33*06 F 905 90.83 198/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CATSPSDFDRRWGYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cgtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaggggtctggaatggttggcaatgatatggtatgatggaaataaaaaatactacgcagactccgcgacgggccgattcaccatctccagagacaattctgagtacacgctgtctcttcaaatgaacagcctgagagtcgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatggaacgtggtcgtcgcctgcctggtccagggcttcttccccca +16951 JY8QFUQ01CXNBM productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1101 99.55 222/223 nt 98.65 220/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-7*01 F 3 8 10 13 8.10.13 [1.16.38.11] CTTISIWNYMFEGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) cctctggattcactttcagtaacgcctggatgagctgggtccgccaggctccagggaaggggctggagtggttggccgtattaaaagcaaaactgatggtgggacaacagactacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcaaaaaaTcacgctgtatctgcaaatggacagcctgaaaaccgaggacacagccgtgtattactgtaccacaatttcgatctggaactatatgtttgagggctactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgcccccaaaccctt +16952 JY8QFUQ01B97DO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 986 94.95 207/218 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD3-9*01 F 2 8 8 18 8.8.18 [1.17.38.11] CVKVAGDYRTPNYGWHFDLW in-frame - cctctggattcacctttagcacctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggtagtggtggcagcacattctactcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactggatctgcaaatgaatagcctgagaggcgaagacacggccgcatattactgtgtgaaagtggccggtgactatagaactcccaactacggctggcacttcgatctctggggccgaggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16953 JY8QFUQ01AE8MS No results +16954 JY8QFUQ01B8TQS productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 907 92.02 196/213 nt 91.55 195/213 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 7 12 8.7.12 [0.17.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) tggattcagcttcagtacctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtactaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattattgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16955 JY8QFUQ01BBJ0Z No results +16956 JY8QFUQ01B5MTP productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16957 JY8QFUQ01AU2SR No results +16958 JY8QFUQ01CNXIW No results +16959 JY8QFUQ01B1ENW No results +16960 JY8QFUQ01AWY0D No results +16961 JY8QFUQ01C9KNG unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F (see comment) 804 84.75 189/223 nt Homsap IGHJ3*01 F 160 80.0 40/50 nt Homsap IGHD3-10*01 F 1 8 10 X 8.10.X [1.17.38.11] CARIWEPSITFLHT#FDVW out-of-frame + stop codons Low V-REGION identity (84,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttcggggttcacctttggtgactatgctatcagttggttccgccaggctcctgggaaggggctggagtggattgctctccttaggagcaaaccttataattcaccaacacaattcgccacgtctgtgaaaggccgattcactgtctcaagagatgactcggaaagtgtcgcctatctgcacatgaacagcctgcaaaccggggacacagccgtgtattattgtgccagaatatgggaaccaagtattactttccttcatacattttgatgtctggggccgagggacacgggtcaccgtttcttcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16962 JY8QFUQ01B2SXL productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 903 91.59 196/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame + ttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16963 JY8QFUQ01BO8QL unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1110 100.0 223/223 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFFGLL# out-of-frame + stop codons ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgga +16964 JY8QFUQ01CZ42C unproductive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 961 94.84 202/213 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 3 9 7 X 9.7.X [X.17.38.11] CARGETDCRVLL*LL# out-of-frame + stop codons ggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaactgactgccgagtactactttgattactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +16965 JY8QFUQ01BT0XX productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 89.77 193/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKINNDFGDYDWFDPW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactggGgggcaccgactccaaccCcctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaatcaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggggcttcttccccccgag +16966 JY8QFUQ01B89QH productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 905 90.83 198/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16967 JY8QFUQ01CD9SW productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 885 90.65 194/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 8 8 20 8.8.20 [0.17.38.11] CTRTQFDPDYGDYETGYGMDVW in-frame - tggattcaacttccgatcttatgccatgtactgggtccgccaggccccaggcaaggggctggactgggtggcagttatttggcatgatggcagtaatcaatactatgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacattgtttctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtacgaggacgcaatttgaccctgactacggtgactacgagacggggtacggtatggacgtctggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16968 JY8QFUQ01BMYLY No results +16969 JY8QFUQ01C4D2U No results +16970 JY8QFUQ01CYV65 productive (see comment) Homsap IGHV3-7*01 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARVRGYYGGQYFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 27 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); agcctctgGgattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16971 JY8QFUQ01BLAYF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD4-11*01 ORF 3 8 8 12 8.8.12 [1.17.37.11] CARHLTPEDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 169 in the user submitted sequence), (cause frameshift) cctctggattcacctttgacaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtgttagtggtcctggtggtaacacataccacgcagactccgtgaagggccggttcaccgtctccagagacaattccaagaacatgctgttctgcaaatgaacagtctgagggtcgaggacacggccgtttattactgtgcgagacacctgactccagaggatgcttttgatatttggggccaagggacaatggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16972 JY8QFUQ01CROU6 productive Homsap IGHV3-30*01 F 869 88.99 194/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16973 JY8QFUQ01CCGF5 productive (see comment) Homsap IGHV3-11*01 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD1-26*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARDGDDYRSYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggaAtttcacacattagtagtagtggtagcatggtatacctggcagactctgtgaagggccgattcatcatctccagggacaacggcgagaactcactgtatcttcaaatgaacagcctgagagccgaagacacggccgtgtattactgtgcgagagatggggacgactacaggtcgtactactatggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16974 JY8QFUQ01DHQXI productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1013 96.33 210/218 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDVW in-frame + cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc +16975 JY8QFUQ01C10RQ unproductive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + ctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16976 JY8QFUQ01BYF03 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctgtcaaggactanttcccccgaaccggtgacggtgtcgtggaactc +16977 JY8QFUQ01BIUGN No results +16978 JY8QFUQ01CVL82 unproductive (see comment) Homsap IGHV3-48*03 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDLNWSFDS# out-of-frame + stop codons in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); cctctggattcacctttactagttaCagttttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctgtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccctaaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca +16979 JY8QFUQ01BHSLV No results +16980 JY8QFUQ01B0PWQ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16981 JY8QFUQ01AQ6QH productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 896 90.37 197/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) gcctctggatcacctttggttattgatggcatgactgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16982 JY8QFUQ01AN7XN productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); tctggattcaccttCcgggaactatagcatgaactgggtccgccacgctccagggaaggGggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16983 JY8QFUQ01CH91E unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16984 JY8QFUQ01BBZE4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 863 89.3 192/215 nt 88.37 190/215 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 7 13 8.7.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaAaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16985 JY8QFUQ01CHJ2M unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtctcccctgcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16986 JY8QFUQ01A8NJV unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag +16987 JY8QFUQ01BHPWK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1014 95.91 211/220 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) agcctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16988 JY8QFUQ01CLQEI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16989 JY8QFUQ01B7QCF productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 881 90.23 194/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 9 8.7.9 [1.17.38.11] CARGGSYFWDW in-frame - tctctggtggctccaccaataataactactggacttggatccggcagcccccagggaagggaatggagtgggttgggtatgtcaattatgctgggaccaccaactacaacccctccctcaagagtcgagtcactatttcagtggactcgtccaagaaccagttctccctgagggtgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggcagctacttctgggactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16990 JY8QFUQ01AARUN productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1062 96.9 219/226 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - taccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16991 JY8QFUQ01CTI25 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - ctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +16992 JY8QFUQ01AI9DI productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 855 88.48 192/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CTRVGTFNWFGPW in-frame + ctctggattcaactttgcggattatggcttgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +16993 JY8QFUQ01B4I9E productive Homsap IGHV3-48*03 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARESWWSGFYGWYDPW in-frame + ctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +16994 JY8QFUQ01B9LAR productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) cctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggcGtggagtgggtctctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccCctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +16995 JY8QFUQ01C0KUX No results +16996 JY8QFUQ01BVI82 productive (see comment) Homsap IGHV3-7*01 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.38.11] CSRLLEEW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'A' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); cctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggAagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +16997 JY8QFUQ01A1MBV productive (see comment) Homsap IGHV3-9*01 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [2.17.38.11] CAKDVTSESHFFALDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); gcctcgggattcaagtttgatgaatatgccatgcactGgggtccggcgagttccagggaggggcctggagtgggtctcagttataagttgggatggtgatgacatcgcctatgcggactctgtgaagggccgattcagcatctccagagacaacgccaagaactccctgtacctggaaatgagcagtctgagagttgaggacacggccttctattactgtgcaaaggatgtcacatctgaaagtcacttcttcgctttggacgtctggggccaagggaccgcggtcaacgtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +16998 JY8QFUQ01B4G9N productive Homsap IGHV3-48*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaaggggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +16999 JY8QFUQ01ACYCV unproductive (see comment) Homsap IGHV3-48*02 F 976 94.91 205/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGGG*PVFS#YYSGLDVW out-of-frame - stop codons tctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcggggggagggtgacccgttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17000 JY8QFUQ01CMDEJ productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17001 JY8QFUQ01C7ERG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ3*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARVMREHYYGAGNYPSGGN#EVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 78 of V-REGION: 'G' (1 nucleotides at position 139 to 139 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacaactatgccatgacctgggtccgccaggctccggggaaggggctggagtgggtctcagctatcagtggcagtggcggtaccacttactacgcagactccgtgcagggccgcttcaccaGtttccagagacaatcacgaaaacaccctgtatctggaaatgagtagcctgagagccgaggacgcagccgtctattactgtgcgagagtgatgagggaacattattatggagcggggaattatccctcgggggggaatggaagtctggggccaggggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17002 JY8QFUQ01CON7Y productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17003 JY8QFUQ01AQ9C2 No results +17004 JY8QFUQ01CRQ7V No results +17005 JY8QFUQ01BFROD productive Homsap IGHV4-39*02 F (see comment) 757 83.11 182/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 10 7 22 10.7.22 [1.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame + Low V-REGION identity (83,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17006 JY8QFUQ01BVO9P No results +17007 JY8QFUQ01C7DQY unproductive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 821 85.97 190/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 10 7 12 10.7.12 [1.17.38.11] CARAGGWTPYFDSW in-frame - stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'T' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcaacagtggtaattactactggaactggatccgccaAttccccagggaagggactggagtggattggatatatctactaTgcttggggccaccaacctcgcctcctccctcaagaaccgagtcaccatatcgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccatatattactgtgcgagggccggtggctggaccccctactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17008 JY8QFUQ01C7802 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17009 JY8QFUQ01A3Y4U productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17010 JY8QFUQ01A2O5S No results +17011 JY8QFUQ01CJPZ5 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 975 93.27 208/223 nt Homsap IGHJ3*01 F 142 76.0 38/50 nt Homsap IGHD2-15*01 F 1 8 10 X 8.10.X [1.17.38.11] CAADGCPGGTCYHGFD#VG out-of-frame - ctctggattcactttcagtaacgtctggatgcactgggtccgccaggctccaggaaaggggctggagtgggttggccgtattagaagcaaaactgctggtggggcaacagaatacgctgcgcccgtgagaggcatattctccatctcaagagatgattcaaagaacacgttgtatctgcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtgccgcagatggttgtcctggtggtacctgctatcatggttttgatatgtgggggcccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17012 JY8QFUQ01CW8RX productive (see comment) Homsap IGHV3-11*01 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggGggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17013 JY8QFUQ01AMCC5 productive (see comment) Homsap IGHV4-59*03 F 939 93.46 200/214 nt 92.52 198/214 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD3-22*01 F 2 8 7 18 8.7.18 [1.17.37.11] CARGLYYYTSGYPHDAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) tctctggtgactccatcaatgcttactattggagctggattcggcagTcccccagggaagggactggagtggattggacatgtctattatagtgggagcaccaactacaaccctccctcaagagtcgagtcaccatatcagtagacatatccaagaaccaattctccctgaagctgaactctgtgaccgctgcggacacggccgtgtatcactgtgcgcgggggctctattattatactagtggttatccccatgatgcttttgatgtctggagccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17014 JY8QFUQ01B9QYJ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame + cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtc +17015 JY8QFUQ01B9BWL No results +17016 JY8QFUQ01CLHDB productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccctaaggtcttcccgctgagcctcctgcagccacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17017 JY8QFUQ01CW4A7 No results +17018 JY8QFUQ01CXPRB productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame - ctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17019 JY8QFUQ01CQECM unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 919 91.32 200/219 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) gcctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17020 JY8QFUQ01ACCKR No results +17021 JY8QFUQ01AI3Y4 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 982 94.52 207/219 nt 93.61 205/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [2.17.38.11] CAKDFTYAFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); gcgtctggattcacGgttcagtagttatggcatgcactgggtccgccaggctccaggcaaggGggctggagtgggtggcaatcatctggtatgatggaagtaatcaatattatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacggtgtatctacaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgaaagattttacgtacgcctttgatctctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17022 JY8QFUQ01C89NK productive Homsap IGHV4-4*07 F 800 86.05 185/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtcttgcaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17023 JY8QFUQ01CLSTV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 825 86.36 190/220 nt 85.0 187/220 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [2.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'GT' (2 nucleotides at position 42 to 43 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 61 to 62 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 108 to 108 in the user submitted sequence), (cause frameshift); aatgtctggattcacatttagaagctattccatgaattgggGTccggccaggctccagggGAagggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17024 JY8QFUQ01AR4UT productive Homsap IGHV4-61*02 F 929 91.4 202/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARATLSDVDTPLGFDYW in-frame + tctctggtgtctcaatcacgagtggaagtcactactggaattggattcggcagcccgccgggaagggaccggagtggattgggcgtttctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccgtatcagcagacacgtccaagaaccggctctccctgaagctgagatctttgaccgccgcagacacggctgtttattactgtgcgagagcaaccttgtctgacgtggatacacctttgggctttgactactggggccagggaatcttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17025 JY8QFUQ01DOUDD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcattcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17026 JY8QFUQ01ANJ7T unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 684 88.95 153/172 nt 88.37 152/172 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD1-1*01 F 1 10 7 X 10.7.X [1.17.22.11] CARRGDADNYWYFDL## out-of-frame - Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 68 of V-REGION: 48 nucleotides (from position 113 in the user submitted sequence), (do not cause frameshift) ctctggtgactccattggtagtagtgcttactactggggctgggtccgccagcccccagggaaggggctcgaatggatagggaatatttactatggtggcagcacctactacaaccagctcttcctggagctgacctctgtgaccgccgcagacacggctgtgtattactgtgcgagacggggagatgcggataactactggtacttcgatctctgggggccgtggcaccctggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17027 JY8QFUQ01CFRYC unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 981 94.93 206/217 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + ctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17028 JY8QFUQ01AYHDJ unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17029 JY8QFUQ01A8MMQ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgga +17030 JY8QFUQ01ABPW1 unproductive (see comment) Homsap IGHV3-30*01 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CVGDLTGGSVLL*Q*WFKVL# out-of-frame + stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctagattcaccttcagtagctataatatgcactgggtccgccaggctccaggcaaggGggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgtgggagatttaactgggggttccgtattattatgacagtagtggtttaaagtactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +17031 JY8QFUQ01B2DSB productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 891 90.32 196/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 8 8 20 8.8.20 [1.17.38.11] CTRTQFDPDYGDYETGYGMDVW in-frame + ggctggattcaacttccgatcttatgccatgtactgggtccgccaggccccaggcaaggggctggactgggtggcagttatttggcatgatggcagtaatcaatactatgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacattgtttctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtacgaggacgcaatttgaccctgactacggtgactacgagacggggtacggtatggacgtctggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +17032 JY8QFUQ01BTFHC No results +17033 JY8QFUQ01CCV1Y productive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1008 94.25 213/226 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-11*01 ORF 3 8 10 18 8.10.18 [2.17.38.11] CVRHEGTPVSDVGGYGMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) agcctctggtttcacgttcagtggctctgctatgcactgggtccgccaggcttccgggaaagggctggagtgggttggccgtattagaagtaaagcttacagttccacgacagcatatgctgcgtcggtgaaaggcaggttcaccatttccagagatgattcaaagaacacggcgtatctgcacatgaacagtgtgataaccgaagacacggccgtgtattattgtgttagacatgaagggactcccgtaagtgatgtaggaggatacggcatggacgtctggggccaggggtccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17034 JY8QFUQ01CT8RT No results +17035 JY8QFUQ01AMI0N productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17036 JY8QFUQ01AWFGB No results +17037 JY8QFUQ01CZ4IP productive (see comment) Homsap IGHV1-58*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD3-9*01 F 1 8 8 14 8.8.14 [0.17.38.11] CAAVLAGWGFYYFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); tggattcacctttaaaagttctgctatacagtgggtgcgacaggcccgtggacaacgAccttgagtggataggatggaccgccgttggcagcggtaacacagactacgcacagaagttccaggaaagagtcaccattacgagggacatgtccacaagcacagtctacatggagatgatcaacctgggatccgaggacacggccgtgtattactgtgcggcagtcttggccggctggggattctattacttcgatttctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17038 JY8QFUQ01BRETI No results +17039 JY8QFUQ01B9J97 No results +17040 JY8QFUQ01CECYU unproductive Homsap IGHV4-61*02 F 893 89.59 198/221 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 10 7 X 10.7.X [1.17.38.11] CARQGDSSGPWNDY## out-of-frame + tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaact +17041 JY8QFUQ01BYBMJ No results +17042 JY8QFUQ01B5A9R productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17043 JY8QFUQ01BNWCY productive Homsap IGHV3-7*01 F 901 92.38 194/210 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 7 8 14 7.8.14 [X.17.38.11] CVRGRDGVNFGEMDYW in-frame - ttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17044 JY8QFUQ01CUK2I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.99 194/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattctaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17045 JY8QFUQ01DB34V productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 813 86.92 186/214 nt 86.45 185/214 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKESLVRGVISYYFDDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) ctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggtttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctggttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17046 JY8QFUQ01B7ZOL unproductive Homsap IGHV3-11*01 F 833 87.16 190/218 nt 86.7 189/218 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CVREVTGVWDWFDS## out-of-frame + in CDR1-IMGT at codon 35 of V-REGION: 'A' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaAaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgactcctggggccggggcaaccctggtcaccgtctcctcagcatcccctgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggtcttcttcccccaag +17047 JY8QFUQ01BRPGP productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17048 JY8QFUQ01B9RA3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca +17049 JY8QFUQ01CUAUN unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt 8 8 X 8.8.X [1.17.38.11] CAKDLFQVSTTYFDY (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); cctctggattcacctTtcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactgggccgggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17050 JY8QFUQ01C4D0M productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 926 92.56 199/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacccttctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +17051 JY8QFUQ01BVVMQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame + ctctggattcacctttacctactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17052 JY8QFUQ01B58JB productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1091 99.55 220/221 nt 99.1 219/221 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [2.17.38.11] CARDFFIGGYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift); cagcctctggattcaccttcagtagctatagcatgaactGgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17053 JY8QFUQ01AWGMD productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17054 JY8QFUQ01BCFAZ productive (see comment) Homsap IGHV3-33*04 F (see comment) 711 81.11 176/217 nt 80.65 175/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.16.38.11] CARDILDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) catttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17055 JY8QFUQ01DR04K unproductive Homsap IGHV3-72*01 F 1011 95.07 212/223 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYD#PG out-of-frame + ctctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17056 JY8QFUQ01DJQ8O productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17057 JY8QFUQ01CGTLT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +17058 JY8QFUQ01CT89Y productive (see comment) Homsap IGHV3-7*01 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); cctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca +17059 JY8QFUQ01DQWZD unproductive Homsap IGHV3-72*01 F 1083 98.65 220/223 nt Homsap IGHJ6*04 F (see comment) 108 66.67 36/54 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYDP## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17060 JY8QFUQ01C2LHC unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); cctccggattcaccGtttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17061 JY8QFUQ01B6MMH unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +17062 JY8QFUQ01AZ9UV unknown (see comment) Homsap IGHV3-21*04 F (see comment) 734 81.65 178/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaaggtcttcccgctgagcctcaacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17063 JY8QFUQ01A3X5O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 797 85.32 186/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD2-21*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDPQQILAEVNWFDPW in-frame + cctctggattcacctttcgcagctacgccatgagttgggtccgccaggctccaggaagggggctggagtgggtcttctcaatcagtggcagtggtgataaaacaaaatatgcagactccgtgaagggccgattcaccatctccagagacaatgcgaggaatactttttatctgcatatgaacagcctcagagccgcggacacgggcgtctactattgtgcgaaagatcctcagcagatactggcagaagtaaactggttcgacccctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17064 JY8QFUQ01A732T productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F (see comment) 728 82.33 177/215 nt 81.86 176/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARDKGGSYFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); tctctggtggctccctccatagtgactactGggagctggatccgccagcccccagggaagggactggagtggatcggttacatctcctatagtgggaagaccacatacagcccctccctcaggggtcgactcaccttatcattggacaagtccaggaggcagatctcactgaatctgactgatgtgcacgctccggacacggccgtctattattgtgcgagagataagggagggagttactttgactcctggggccagggaacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17065 JY8QFUQ01AMW1U productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 761 83.49 182/218 nt 82.11 179/218 nt Homsap IGHJ3*02 F (see comment) 142 76.0 38/50 nt Homsap IGHD1-1*01 F 3 8 8 17 8.8.17 [2.16.38.11] CAKDIWAREWNDMAAFQMW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 44 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) gacccccggaatcacTttttcccagctatgtcatgagttgggtcgccaggcccagggaaggggctggagtgggtcgcaagcattagtgccaggggcgacagttcatactacgcagactccgtgaagggccgattcaccatctccagggacaatcccaggaccacattgtatctggaaatgaacagtctgagagtcgaagacacggccacatattattgtgcgaaagatatctgggcgcgagagtggaacgacatggcggcttttcagatgtggggccaggggacacttgtcattgtctcgtcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17066 JY8QFUQ01C636U productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1075 100.0 216/216 nt 99.54 215/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 7 8 22 7.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 37 of V-REGION: 2 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagctagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17067 JY8QFUQ01AIGU7 productive (see comment) Homsap IGHV3-7*01 F 846 88.02 191/217 nt 87.1 189/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.16.38.11] CTRDINYSDNGAYYDVFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) cctctggaGtttaccttcagtaatgattggatgatctgggtccgccaggcgccagggaagggactggagtgggtggccacataaggaaagattcaagtatcaaatattatgctgactctgtgaagggccggtttaccgtctccagagacaacaccaagaagtcactgtatctgcaaatgaacaacctgagagccgaggacacggctgtgtactattgtacaagagatattaattactctgataatggtgcatactatgatgtctttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17068 JY8QFUQ01DM63Z productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 913 91.67 198/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARPGGIAYCSGGSCYDPW in-frame + tcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggggcttcttccccca +17069 JY8QFUQ01BFDXK productive Homsap IGHV4-4*07 F 1061 99.53 214/215 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD4-11*01 ORF 2 8 7 13 8.7.13 [1.17.38.11] CARDFSNRGWYFDLW in-frame + tctctggtggctccatcagtagtttctactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +17070 JY8QFUQ01ASKSP No results +17071 JY8QFUQ01C8DHL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1008 96.31 209/217 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDVW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +17072 JY8QFUQ01CEN45 productive (see comment) Homsap IGHV4-39*03 F 929 91.36 201/220 nt 90.91 200/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcCccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17073 JY8QFUQ01BH73X productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 920 90.95 201/221 nt 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 14 10.7.14 [1.17.38.11] CARRALDSSGHYIDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); tctctggtggctccatgagcagtggtaattactgctggggctggggccgccagccCcccaggaaaggggctggagtggattggaagtatgtgttatggtgggagcacctactacagcttgtCcccccaagggtcgagtcaccatatccatagactcgtcgaagaaccagttctccctgaggctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagacgcgcattagacagtagtggtcattacattgacatctggggccagggaatcctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +17074 JY8QFUQ01BB7WV productive Homsap IGHV3-9*01 F 918 91.71 199/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVKGAGTTVNWFDIW in-frame + ctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatggatctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17075 JY8QFUQ01CT4ON productive Homsap IGHV3-48*03 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARESWWSGFYGWYDPW in-frame + ctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17076 JY8QFUQ01DBRLD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame - cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17077 JY8QFUQ01BVMQQ productive (see comment) Homsap IGHV1-18*01 F 1020 97.66 209/214 nt 97.2 208/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [0.17.38.11] CARNIVGAPFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'GC' (2 nucleotides at position 45 to 46 in the user submitted sequence), (cause frameshift); tggttacacctttaccagctatggtatcagctgggtgcgacaggGCcccctggacacgggcttgagtggatgggatggatcagcgcttacaatggtaacacaaagtatgcacagaagctccaggacagagtcaccatgaccacagacacatccacgagcacagcctatatggagctgaggagcctgagatctgacgacacggccgtttattactgtgcgaggaatatagtgggagctccttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag +17078 JY8QFUQ01BY9RZ productive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 844 88.73 189/213 nt 88.26 188/213 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [0.16.38.11] CARSSGGFYYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) tggaggctccttcagcagctttactatcaactgggtgcgacaggcccctgacaagggcttgagtggatgggcgggatcatccccatcttgagtgcagcaaactccacacagaggttccaggtcagagtcacattgaccgcggacgcatccacgggcacagcctacatggagttgaacaggctgacatatgaggacacggccgtttattactgtgcgcggtcgagtggtggtttctactacgctatggacgtctggggccaagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17079 JY8QFUQ01AOJXD productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 791 85.58 184/215 nt 85.12 183/215 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CATVRHLGERIFDFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); tctctgggggcCaccatgagtagtttctactggagctgggttcggcagtccccagggaggggactggagtggattggatttgtttcttacagtgggcccaccaactacagcccctccctcaagagtcgagtcaacttatcactggacgcggccaacaaacagttctctttgcagctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17080 JY8QFUQ01C57J2 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 774 83.87 182/217 nt 83.41 181/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17081 JY8QFUQ01C2SJA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDGMMTFGGVIVPSRFFFDYW in-frame + ctctggattcagctttggtgactatgtcatgagctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtagcggtggaactacatattatgcagactccgtgaagggccggttcaccatttccagagacaactccaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgaaagatggaatgatgacgtttgggggagttatcgtccccagtaggttcttctttgactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaaagatgggaaccntgggtcgtcgcatgcctggtccagggcttcttccccca +17082 JY8QFUQ01BH9O9 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 913 91.67 198/216 nt 90.28 195/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.16.38.11] CARKGPRRDGSLQQCDMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 32 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) ctgctggattcatcttcagcaaccttgcgatcactgggtccgccagctccaggcaaggGggctggagtgggtggcaattatatcacatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +17083 JY8QFUQ01AOSD4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD2-15*01 F 2 8 8 21 8.8.21 [1.17.38.11] CAKTGGQCSGGNCYLHYYGMDVW in-frame + ctctaaattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcacaggtattagtggtggtggtgaaaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagagcatgttgtatctgcaaatgaacagcctgagagccgaagacacggccgtattttactgtgcgaaaactggcggtcaatgcagtggtggtaactgctatttgcactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +17084 JY8QFUQ01CMEXL No results +17085 JY8QFUQ01CZ9ZV productive Homsap IGHV1-18*01 F 867 89.72 192/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 8 8 8 8.8.8 [0.17.38.11] CARDRPNEFW in-frame + tggttacccctttaatacctatggtatcacctgggtgcgacaggcccctggacacggccttgagtggatggggtggatcagcgttcacgatggcaacacaaactatgcacagaatctccagggcagagtcaccctgaccacagacacatctacgagcacagtctacatggaactgaggggtctcagatctgacgacacggccgtttattattgtgcgagagatcgcccgaatgaattctggggccagggaaccctggtcaccgtcttctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +17086 JY8QFUQ01B53SB productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 696 80.84 173/214 nt 80.37 172/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggGggcggcttatcgatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +17087 JY8QFUQ01CB1I8 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 7 10 9.7.10 [1.17.38.11] CASHGGKYFPQW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); tctctggtggcGtccatcagcagtagtaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggacaaatccatcatggtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17088 JY8QFUQ01CUVTZ productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 7 8 13 7.8.13 [2.17.38.11] CVSDRELHYQHLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) gcgtctggattcaactcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17089 JY8QFUQ01CHBJS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKRRGGYYIDFDYW in-frame + cctctggattcacctttactagttacagtttcaattgggtccgccaggctccagggaaggggctggagtgggtctcaactatcaatactagtggtagtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacgaggtgtatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaagcggaggggtggttattacatcgactttgactactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17090 JY8QFUQ01CVO3G productive Homsap IGHV1-2*02 F 921 92.52 198/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-16*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARISHRGLGYDLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tggatacaccttcaccggctactatatgcactgggtgcgacaggcccctggacaaggccttgaatggatgggctggatcaaccccaacactggtggcacaaattttgcacggcagtttcagggcagggtcgccatgaccagggacacgtccatcaacacagcctacatggacctgaccaggctgcaatctgacgacacggccgtttattactgtgcgagaatttcccatcgggggctagggtacgatttggacgtctggggccacgggaccacagtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +17091 JY8QFUQ01CVKBH No results +17092 JY8QFUQ01DVUMR unproductive Homsap IGHV3-30*01 F 915 90.91 200/220 nt 90.45 199/220 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD6-6*01 F 3 8 8 X 8.8.X [2.17.38.11] CAREWAASHFDH## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 38 of V-REGION: 'A' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); agccgctggattcaccttcagtggctttgcAtttgcactggctccgccaggctccagacaaggggctagagtgggcgggatttacatcatttgatgggagtaacagagactacgcagactccgtgaagggccgattcacgatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagacctgacgacacggctgtatattactgtgcgagagagtgggcagccagtcactttgaccactggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17093 JY8QFUQ01B8QO4 productive Homsap IGHV3-30*04 F, or Homsap IGHV3-30-3*03 F 1053 98.62 214/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-22*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARAPMILVVPKDW in-frame + ctctggattcaccttcagtagcgatgctatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgcatctgcaaatgaacagcctgagagctgaggacacggctgtctattactgtgcgagagccccaatgatactagtggttccgaaggactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17094 JY8QFUQ01AXAHP productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1038 96.41 215/223 nt 95.52 213/223 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 7 10 17 7.10.17 [1.17.38.11] CTRDNPPLRSLEWLPFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) cttctggatcacctttggtgattaGtagtatgagttggttccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcaaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17095 JY8QFUQ01CSN8V No results +17096 JY8QFUQ01BUL6F No results +17097 JY8QFUQ01ARJ9A productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 822 85.65 191/223 nt 84.75 189/223 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [2.17.38.11] CVRHVRRFWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 31 of V-REGION: 'C' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); gtctctaatgggctccatcagCcggaagtgtttactactgggcctggatccgccagcccccagAgaaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17098 JY8QFUQ01CZFUL productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 926 90.62 203/224 nt 90.18 202/224 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-11*01 ORF 2 8 10 22 8.10.22 [1.17.38.11] CATDRPYYKNAAGRLWYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); gctctggattcactttcactaacgcgtggatgagttgggtccgccaggctGccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaacgctgctggccgactctggtattactacggtatggacgtttggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17099 JY8QFUQ01DIUIX unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 929 91.4 202/221 nt 90.05 199/221 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSYGF#SVDPW out-of-frame + in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaccagtagtCttttaccgctggggctggatccgccagtccccagggaagggcctggagtggatAggggaatatcttttatggtgGggaccacctactacaacccgtccctcaagagtcgagtcaccttatccatagacacgtccaagagccagttctccctgaagctgtcctctgtgaccgccgcagacacggctctatattactgtgcgagatcgtacggtttctctcggtcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +17100 JY8QFUQ01AEB8Z productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - gcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17101 JY8QFUQ01CU8EK productive (see comment) Homsap IGHV3-7*01 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.17.38.11] CVRDRPGGWALDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGcttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17102 JY8QFUQ01CLVAK No results +17103 JY8QFUQ01CKLTT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 875 88.69 196/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - cagcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17104 JY8QFUQ01BSUY0 No results +17105 JY8QFUQ01AU6Q0 unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17106 JY8QFUQ01DV1NC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*02 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDRYPRSTAITAPDYW in-frame + cctctggattcccctttagcaactatgccatgacctgggtccgccaggctccaggggagggactggaatgggtctcaagtattagaggtagtggtgacaggacatcctacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagctgaacaacctgagagccgaggacagggccgaatattactgtgcgaaagatcgctaccctcggtcgacagctattacagcgcctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggctcttcccgctgagcctctgcagcacccagccagcatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccagg +17107 JY8QFUQ01AE063 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcatcttcagtagctactggatgcactggg +17108 JY8QFUQ01C73QL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17109 JY8QFUQ01C1KKC unknown (see comment) Homsap IGHV3-48*01 F (see comment) 590 74.31 162/218 nt 72.94 159/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (74,31% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttatagcatgaactggGgtccgccaggctccagggaaGggggctggagtggAttttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagagcacctctgggggacacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17110 JY8QFUQ01DRCDC productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 177 to 177 in the user submitted sequence), (cause frameshift); cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaAatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17111 JY8QFUQ01CJ6A1 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17112 JY8QFUQ01CN2NY No results +17113 JY8QFUQ01CBQ54 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17114 JY8QFUQ01AL5IC No results +17115 JY8QFUQ01CB6XD unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 1 8 8 X 8.8.X [1.17.38.11] CAREGGGQFVG##YFDYW out-of-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaatggtgcttacatatactacgcagactcaatggagggccgattcaccatctccagagacaacgccaggaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgcgagaggggggcgggcagttcgtcggaagactactttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17116 JY8QFUQ01CO47U productive (see comment) Homsap IGHV3-7*01 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 8 14 7.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) ctctggattacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17117 JY8QFUQ01BZT3E unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 593 75.35 162/215 nt 74.88 161/215 nt 8 7 X 8.7.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (75,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctgggtttacctttagcaactttgccatggcttgggtccgccaggctccaagaaaggggctggagtgggtctcagctattgctcgtggcggtgacacacactaccgagactccgtgaagggccgattcaccatctccagagacaattctaagaacacactgattctgcagatgcgtggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17118 JY8QFUQ01BO6OR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 962 94.42 203/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [0.17.38.11] CARVGYGYRGIYFFDYW in-frame - ctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17119 JY8QFUQ01DTZUH unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame - in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccaGgggaaggggctggagtgggtttcataGccttagtagtggtagtgataccatatactacgcagactctgtgaGggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17120 JY8QFUQ01BMLSJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 165 75.0 45/60 nt Homsap IGHD6-19*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARQYTSGEMDGW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctagattcaggttcagtagttataccatgacctgggtccgccaggctccagggaagggactggagtgggtctcatcgatcactagtgggagtagtcatatacactatgcagactcagtgaaaggccgattcaccatctccagagacaacggcaaaaactcactttatctgcaaatggacagcctgagagccgaagacacggctctatattactgtgcgagacaatacaccagtggcgagatggacggctggggccaggggaccacggtcttcgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagcagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17121 JY8QFUQ01CTR9B unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + cctctggattcacctacagcagccatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17122 JY8QFUQ01BB4E3 No results +17123 JY8QFUQ01A2MYW productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1003 96.3 208/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17124 JY8QFUQ01CAKEH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 89.9 187/208 nt 88.94 185/208 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 6 8 17 6.8.17 [X.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 47 to 48 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cacctttaatagctatgccatggcctgggtccgccaggctccagggGAagggggctggagtGgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttcccccgtggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaact +17125 JY8QFUQ01B0Q2W No results +17126 JY8QFUQ01BRIGU unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17127 JY8QFUQ01DQ8N5 productive (see comment) Homsap IGHV4-4*07 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); tctctggtacctccatcagcacttactattggagttCggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgCaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17128 JY8QFUQ01DASZH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagtacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17129 JY8QFUQ01BRS32 No results +17130 JY8QFUQ01AUT33 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 908 91.63 197/215 nt 90.7 195/215 nt Homsap IGHJ4*02 F 95 67.39 31/46 nt Homsap IGHD7-27*01 F 1 8 7 6 8.7.6 [1.17.38.11] CSRLLEEW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 97 of V-REGION: 'G' (1 nucleotides at position 192 to 192 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 88 in the user submitted sequence), (cause frameshift) tccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccGgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17131 JY8QFUQ01AH7BA unproductive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 930 92.99 199/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [0.17.38.11] CAKGSFDSSGRPEAFDI## out-of-frame + Other possibilities: Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggaggcaccttcagtagatatgctttcagctgggtgcgacaggcccctggacaagggcttgagtggatgggagggatcgtccctctctttggttccataaagtacgcacagaagtaccagggcagagccacgattaccgcggacgaatccacgagcacagtctacatggagctgagcagcctgagatctgacgacacggccatgtattactgtgcgaagggttcctttgatagtagtggtcgccctgaggcttttgatatctggggccaagggtacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +17132 JY8QFUQ01ANLMX productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 962 92.41 207/224 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD1-26*01 F 3 8 10 14 8.10.14 [1.17.38.11] CTRDLSGSYSGAFDVW in-frame + gatctggattcacctttggtgactttgctatgagctggtttcgccaggctccagggaaggggctggagtggctaggtttcattagaagcaaaatttatggtgggacaccagaatacgccgcgtctgtgaaaggcagatgtcccatctcaagagatgattccaaaaacatcgcctatctgcaaataaacggcctgaaaaccgaggacacagccatgtatttctgtaccagagatctcagtgggagctactccggtgcttttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17133 JY8QFUQ01AQJ3F unknown (see comment) Homsap IGHV3-74*03 F 133 55.73 73/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +17134 JY8QFUQ01BMZNK productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD3-16*02 F 3 8 7 9 8.7.9 [4.17.38.11] CARGDPIFMIV in-frame + cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggaccccattttcatgatagtgttaaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17135 JY8QFUQ01C90SO unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 937 92.24 202/219 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CVRWKMDRSGVSAAATDVFGMDV## out-of-frame - gcctcgggattcaccttcagtggctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatggtaagaataaatacatctactatgcagactcactgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaccaacctgagagccgaggacacggctctatattactgtgtgagatggaagatggataggagtggtgtaagtgcagcggcaacagacgttttcggtatggacgtctgggggccaagggaccacagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17136 JY8QFUQ01ANOOW productive Homsap IGHV4-39*07 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 9 7 15 9.7.15 [1.17.38.11] CARAVLDNAWPIYYDFW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (9 AA in JY8QFUQ01ANOOW ; 10 AA in Homsap_IGHV4-39*07), and low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctggtggctccatcaccacttggcattactggggctggatccgccagcccccaggggagggtctggaatggattggaaatgtctatcataatggcaatatcgcctatagcccgtcgcagaggagtcgaatcaccatatcagtagacacgtccaggaaccagttctccctgaagatgacctctgtgaccgccgcggacacggctgtctattactgtgcgagggctgttcttgacaatgcctggcctatatattatgacttttggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17137 JY8QFUQ01B8J97 No results +17138 JY8QFUQ01AVKTX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [0.17.38.11] CMNELGYCSGGG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); ctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggGggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtggggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17139 JY8QFUQ01DXGB2 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-6*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRSYSRTSEFDYW in-frame + cgtctggattcagtttcagtacctttggcatgagttggatccgccagacgccaggcaaggggctggagtgggtgacagttatatggtcggatggaactaaaaaaatttatgcagactccgtgaagggccgattcaccatctccagagacaatgtcaagaacacggtttatctgcagatgagcagcctgagagtcgaggacacgggcgtatattattgtgtgaggtcgtatagtaggacatctgagtttgactactggggcccgggaacccaagtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17140 JY8QFUQ01DLVUV unproductive (see comment) Homsap IGHV4-31*06 F 996 94.98 208/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CARVIIDDSGGNY#FDYW out-of-frame - stop codons ctctggtgcctccatcagcagtggtatttactactggagctggatccgccagcacccaggggagggcctggagtggattgggtacatctctgacagtgggagcacctactacaacccgtccctcaagagtcggtttaccgtatcagtggacacgtctaagaaccagttctctttgaagctgagctctgtgactgccgcggacacggccgtgtattactgtgcgagagtaataatagatgactccggtggtaactacctttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttcccccctggcgcccctgctccaggagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17141 JY8QFUQ01C3DN4 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctgggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17142 JY8QFUQ01CJEDT productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +17143 JY8QFUQ01CODA3 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17144 JY8QFUQ01CZ6MM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaactttggtgactttgtcatgacttgggtccgccaggctccagggaagggactagaatgggtctcatctattagtggtactggtactctcacttactacggaaactccgtgaagggccacttcaccatctccagagacaattccgacaacacagtctatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17145 JY8QFUQ01CCHJL productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17146 JY8QFUQ01BCRD7 No results +17147 JY8QFUQ01CXLQ9 unproductive Homsap IGHV1-3*01 F 621 95.59 130/136 nt 94.85 129/136 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-21*02 F 3 8 X X 8.X.X [0.3.34.11] CTRGRGAGNFPPNPI#FDPW out-of-frame + in FR2-IMGT, from codon 42 of V-REGION: 78 nucleotides (from position 35 in the user submitted sequence), (do not cause frameshift) tggatataccttcactagttatgctatacattggaacttccagggcagagtcaccattaccagggacacatccgcgagcacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtatttctgtacgagaggccggggggcagggaacttccctcccaaccctattgttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaatgatgggaacgtggtcgtcgcatgtctggtccagggcttcttcccccga +17148 JY8QFUQ01DHGWP unproductive Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 661 78.24 169/216 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt 8 8 X 8.8.X [1.17.38.6] RTGD (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Low V-REGION identity (78,24% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17149 JY8QFUQ01AFGYG productive (see comment) Homsap IGHV3-30*01 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [1.17.38.11] CVKNDLSWGTIEHYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcacgttcaacatttatgGgtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17150 JY8QFUQ01AWDVJ productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattattcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17151 JY8QFUQ01DP1K8 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 9 8.7.9 [4.17.38.11] CARGDPSFHDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggaccccagttttcatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccccttggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17152 JY8QFUQ01B7OB3 No results +17153 JY8QFUQ01ANMUX No results +17154 JY8QFUQ01DCZPW productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagGggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17155 JY8QFUQ01AU8W0 No results +17156 JY8QFUQ01DHW2H productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-25*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARHEGYNSRYYYFGYW in-frame + ttctggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17157 JY8QFUQ01AZEES productive Homsap IGHV3-72*01 F 957 92.38 206/223 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 10 14 8.10.14 [1.17.38.11] CARLHYSGGWYGLDVW in-frame + ctctggattcaccttcagtgaccactacatagactgggtccgccaggctccaggaaaggggctggagtgggttggccgtactcgaaataaagctaacggttacagtacagagtatgccgcgtctgtgaaaggcagattcaccgtctcaagagatgactcagagaacttagtgcatctgcaaatgaacagcctgaaaagcgaggacacggccctgtattactgtgctagactgcactacagtggtggctggtacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17158 JY8QFUQ01A59ZU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-21*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtttattactgtgcgagaggccgaatagtgtcggttggtatgtcaggctggttcgacccctggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +17159 JY8QFUQ01AM0UE productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc +17160 JY8QFUQ01CP0O1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 867 89.72 192/214 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVSDLAGQKGSW in-frame - aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17161 JY8QFUQ01ALADF unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1022 96.79 211/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-25*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGGW*R##LDYW out-of-frame + stop codons cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggatggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaactgtgtcgtcgcatgcctggtccagggcttcttccccca +17162 JY8QFUQ01CWY4Y unproductive Homsap IGHV4-61*03 F 876 88.34 197/223 nt 87.89 196/223 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-23*01 ORF 3 10 7 X 10.7.X [2.17.38.11] CTRHPKSNVEGDS## out-of-frame - in FR2-IMGT at codon 45 of V-REGION: 'AC' (2 nucleotides at position 56 to 57 in the user submitted sequence), (cause frameshift); gtcccctggtggctccgtcagcagtggtagttatttctggagctggatccggcagACcccccagggcaggggctggaatggatcggttatgtctataacaatgggaacaccaattacaacccttccctcaagagtcgagtcaccatttctatagacacgtccgagaatcacgtctccctgaagctggcctctgtgaccgctgcggacacggccgtgtactactgtacgaggcacccgaagtctaatgtagagggtgactcctggggccagggagcccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17163 JY8QFUQ01APH2J productive Homsap IGHV1-18*01 F 867 89.72 192/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-8*02 F 1 8 8 23 8.8.23 [0.17.38.11] CVRDIGWTSYKGKWSCTVCDAFDIW in-frame + tggttacacttttagcaattatggtgtcagctgggtgcgacaggcccctggacaaggatttgagtggatgggatggattagcggctccaatggtaaaacagagtatgcacagaagttccaggacagggtcaccatgaccacagacacattcacgagcacagcctatatggagatgaggagcctgagatctgacgacacggccatgtattattgtgtgagagatatcgggtggacctcctataaagggaagtggtcttgtacggtatgtgacgcttttgacatctggggccaagggacaatggtctccgtctcttcagcatcccgaccagccccaaggtcttcccggctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccgagggcttcttcccccc +17164 JY8QFUQ01CZCD5 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggctttttccccca +17165 JY8QFUQ01C2O4Z productive (see comment) Homsap IGHV4-61*02 F 1028 96.38 213/221 nt 95.93 212/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 15 10.7.15 [1.17.38.11] CARAPSYTNSHQHCDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 68 of V-REGION: 'AC' (2 nucleotides at position 116 to 117 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttactactggagttggattcggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaaACcccctccctcaagagtcgagtcaccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctattattgtgcgagagctccctcttataccaactcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggctccttccccca +17166 JY8QFUQ01CHHJB productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 806 85.78 187/218 nt 85.32 186/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [2.17.37.11] CVRDLNWSFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 127 in the user submitted sequence), (cause frameshift) gcctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaaggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17167 JY8QFUQ01CIDRZ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 775 84.02 184/219 nt 82.65 181/219 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [2.17.38.11] CARDSALFGYARYDAMDAW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 38 of V-REGION: 'TG' (2 nucleotides at position 28 to 29 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'T' (1 nucleotides at position 144 to 144 in the user submitted sequence), (cause frameshift); gcctctggatccagtttcagtggttttTGggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggGggccggttcaccatTttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17168 JY8QFUQ01BY57B No results +17169 JY8QFUQ01DIP27 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattcacatttcgaagttattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcggctgtaagtggtggtggcggcgccacaacctacgcggactccgtgaagggccggttcaccatctccagagacaatacacagaagatggtgttcctagaaatgagcagcctgagagtcgaagacacagccttatattattgtgcgcgagatgacgggggacacatgactttagatgtctggggccaggggacaatggtcaccgtctcttcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggcgttcttccccca +17170 JY8QFUQ01DSPF8 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 748 82.65 181/219 nt 81.74 179/219 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [2.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); gcctctggattCcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggGggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17171 JY8QFUQ01BHLSA No results +17172 JY8QFUQ01A9DV9 No results +17173 JY8QFUQ01BUZY7 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17174 JY8QFUQ01AKWWD productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); cctctggattcaGccttcagtagctactggatgcactGgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17175 JY8QFUQ01CWEVR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCGNGACHVADYW in-frame + ctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +17176 JY8QFUQ01B7WOD No results +17177 JY8QFUQ01AGCMW productive (see comment) Homsap IGHV4-61*02 F 969 93.64 206/220 nt 92.27 203/220 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD2-2*01 F 2 10 7 19 10.7.19 [1.17.37.11] CARVVRCTTTGCSRVGWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 216 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagcagtgatgattactactggagctggatccggcagcccgccgggaagggactggagtggattGgggcgtatctcttccagtgggaacaccaactacaaCcccctccctcaggagtcgagtcaacatttcactagacacgtccaagacccagttctccctggagctgacctctgtgagcgccgcagacacggccgtgtatactgtgcgagggtcgttcgttgtactacgaccggctgctcaagggtaggatggttcgacccctggggccagggaaccctggtaaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +17178 JY8QFUQ01B5VSY productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 947 92.31 204/221 nt 90.95 201/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARHGSGWLQELDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'CC' (2 nucleotides at position 79 to 80 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); tctctggtggctGccatcatcagagacagtgcctactggggctggatccgccagccccagggaaaggggctggagtggCCtttgggagcatctattatagtgGggagtacctactacaatccctccctcaagagtcgagtcaccatatccgtagacacgtccaagaagcagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagacatggcagtggctggctccaggaacttgactactggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17179 JY8QFUQ01CQQA9 unproductive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ5*01 F 111 68.63 35/51 nt 8 8 X 8.8.X [1.17.38.11] CARDQVTEDY (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactgggccaggaaccctggtcagtgtctcctcagcctccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17180 JY8QFUQ01BWEUM unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 160 80.0 40/50 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDRLNW*LHIRR#FDLW out-of-frame + stop codons Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) cctctaaatttgacttcagtgactatggcatgaactgggtccgccaggttccagggaaggggctggagtgggtctcctacataagtcgtctgagtcgccaaatatatgtcgctgacccagtgaagggccgattcaacatctccagagacaacgccaagaattcactgtatctgcaaatgaacaacttgcgggtcgaagacacggctgtgtatttttgtgccaaagatcgcctgaactggtgactacacattcggcgcattttgatctgtggggcccagggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacacgcggccctgggctgcctggtcaaggactacttgccccgaaccggctgacggtgtcgtggaactca +17181 JY8QFUQ01AXVM2 unproductive (see comment) Homsap IGHV3-30*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 X 8.8.X [1.17.38.11] CVKK*PVLGHNR##YFDYW out-of-frame + stop codons cctctggattcacgttcaacatttatggtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17182 JY8QFUQ01A151U productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgGggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +17183 JY8QFUQ01BWHJI productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); gtttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17184 JY8QFUQ01CQT8B productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17185 JY8QFUQ01CY1LD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD1-20*01 F 3 8 8 X 8.8.X [1.17.38.11] CANASPRITGTYFYYYGMDV# out-of-frame + Other possibilities: Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctgggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaaactca +17186 JY8QFUQ01B5VXZ No results +17187 JY8QFUQ01CIKB3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17188 JY8QFUQ01CB1U7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-13*01 F 1 8 7 16 8.7.16 [1.17.38.11] CAKTQPFGTTWYGATDAW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctgggtttacctttagcaactttgccatggcttgggtccgccaggctccaagaaaggggctggagtgggtctcagctattgctcgtggcggtgacacacactaccgagactccgtgaagggccgattcaccatctccagagacaattctaagaacacactgattctgcagatgagcagcctaagagccgaggacacggccttatattactgtgcaaagacgcagccgtttggcaccacctggtacggtgctacggatgcgtggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17189 JY8QFUQ01AOPK3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1026 97.24 211/217 nt 96.77 210/217 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CVRGGYYRHDAFHIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaAaggggctggtgtgggtctcacgtattaatagtgatgagagtaccacaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacggtgtttctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgtacgtggtggttattaccgtcatgatgcttttcatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17190 JY8QFUQ01AU7SF No results +17191 JY8QFUQ01B0XOZ productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - ctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17192 JY8QFUQ01DIHPZ No results +17193 JY8QFUQ01CAMSC unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 972 94.47 205/217 nt Homsap IGHJ3*01 F (see comment) 124 72.0 36/50 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKSPSQVGYYLD#VG out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccggcaaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcaccatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17194 JY8QFUQ01CWRKR No results +17195 JY8QFUQ01CWWMH unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 930 92.56 199/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARDCDSGECNFDYW in-frame - stop codons tctgattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggantgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17196 JY8QFUQ01BF6UR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARVRLDIVATIVDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatagtgatgggagtagcacaagctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagttcgcctggatatagtggctacgattgttgactactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaaccc +17197 JY8QFUQ01CGQO6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17198 JY8QFUQ01AQGGO productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctagtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17199 JY8QFUQ01BNGO7 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARDRSNYYSDYW in-frame + gtctggattcattttcagtaattatggcatgcgctgggcccgccaggctccaggcaaggggctggagtgggtggcatttatatggtatgacggaagaaataaatactattcagactccgtgaagggccgattcaccatctccagagacaattccgaggacacgctgtatctggaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagataggagtaattactactctgactactggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17200 JY8QFUQ01ASJTT unproductive Homsap IGHV3-30*01 F 927 91.74 200/218 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDELPWDTIEYYFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcaatattttttctangcactgggtccgccaggctccaggcaagggactagagtgggtgtcacttgtttcatatgatggatctaagaaaaagtacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatgagctgccttgggacacaattgaatattattttgactattgggggccagggaagcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag +17201 JY8QFUQ01DTGSH unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F (see comment) 744 82.27 181/220 nt 81.36 179/220 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [2.17.38.11] TCVRDSDSSGYARYDSMDV## out-of-frame - Low V-REGION identity (82,27% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); agcctctggattcGaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcCggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggatttatacttacttgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctgggggccaagggaccgcggtcaccgtctcatcagccctccacccaaggggccccatcggtcttacccccctggcgcccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactca +17202 JY8QFUQ01COPN0 productive (see comment) Homsap IGHV3-9*01 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); tctggattcacctttaatcaGttatggcatgcactgggtccggcaagttccagggaagggcctggagtgggtctcaggtattagttggaatagcggaagtagagaatatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17203 JY8QFUQ01CWXQD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.16.38.11] CAKRYSGSFYAS##WFHPW out-of-frame + in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcgtctttggcgactatgcgatgagctgggtccggcaggctccagggaggggcgtggagtggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17204 JY8QFUQ01CY9EY productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1001 95.02 210/221 nt 94.57 209/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 2 10 7 12 10.7.12 [1.17.38.11] CVRHRRLELLPDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagcagtaatagttTtctactggggctggatccgccagcccccagggaaggggctggagtggattgggaatatctattatagtgggagcacctactacaacccgtccctcgagagccgagtcaccatatccgtagatacatccaggaaccagttctccctgaagctgaggtttgtgaccgccgcagacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +17205 JY8QFUQ01DWHJ1 No results +17206 JY8QFUQ01DOPW2 unknown (see comment) Homsap IGHV2-5*03 F (see comment) 204 56.25 108/192 nt 10 7 X 10.7.X [9.17.26.X] null - No rearrangement found stop codons Low V-REGION identity (56,25% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccagggacaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17207 JY8QFUQ01C9VHM unknown (see comment) Homsap IGHV1-8*01 F, or Homsap IGHV1-8*02 F 274 93.55 58/62 nt 8 X X 8.X.X [0.12.X.X] null - No rearrangement found tggatataccttcaccagatatgatatcaattgggtgcgacaggccactggacaagggcttc +17208 JY8QFUQ01AGHGA unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +17209 JY8QFUQ01AVPY3 productive Homsap IGHV3-48*03 F 909 91.24 198/217 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDKSAAWYAYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagttctcccatgaactgggtccgccaggctccagggaggggactggagtgggtctcatacattagcagtagtggaactaccacatattacgcagactctgtgcagggccgattcaccgtctccagagacaatgccaagaacctactgtatctgcaaatgaacagcctgagagccgaggacacggctttttattattgtgcgaaagataagagcgctgcctggtacgcctactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17210 JY8QFUQ01B6T1P No results +17211 JY8QFUQ01BTN0C No results +17212 JY8QFUQ01CPROL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 467 89.57 103/115 nt 88.7 102/115 nt 8 7 X 8.7.X [1.17.5.X] null + No rearrangement found in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) tctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccg +17213 JY8QFUQ01CRILY No results +17214 JY8QFUQ01CD483 productive Homsap IGHV3-11*01 F 887 89.91 196/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-7*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARGKGKGGTTYYGMDVW in-frame - cctctggattcactttcagtgactactacatgaattgggtccgccaggctccagggaagggcctggagtggctttcatacattactgcaagtggtgccatcatacactatgcagactctgtgaagggccgattcatcatctccagggacaacgccaagaactcactgtctctgcagatgaacagcctgagagccgacgacacggccgtctattattgtgctcgggggaagggcaagggtggaactacctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17215 JY8QFUQ01ATKO3 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDPRSVSRYSLFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtgactattggatgagctgggtccgccaggctccagggaaggggctagagtgggtggccaacataaatagagatggaagtgagcaacactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacatggctatgtatttttgtgcgagagatcctcgttccgtgagcaggtactctttatttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +17216 JY8QFUQ01B095W unknown (see comment) Homsap IGHV4-4*07 F, or Homsap IGHV4-4*08 F or Homsap IGHV4-59*01 F or Homsap IGHV4-59*07 F or Homsap IGHV4-59*08 F 641 85.14 149/175 nt 8 7 X 8.7.X [1.17.24.X] null + No rearrangement found tctctggtgactccatcagttctgcatacagtaactggatccggcagcccccagggaagggactggagtggattgggtgtattcatcccagtgggactactcattacaacccctccctcaagagtcgagtcgccatgtcaacagacacgtcgaagaaccagttctccctgagact +17217 JY8QFUQ01CV8Z5 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 971 94.88 204/215 nt 93.49 201/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.16.38.11] CARGEMTAEYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 63 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 77 in the user submitted sequence), (cause frameshift) ctctggtggctccatcagcagtgttCaactggtggagttgggtccgccagcccccagggaagggctggagtggattgggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17218 JY8QFUQ01BEIT8 No results +17219 JY8QFUQ01BM6ET productive (see comment) Homsap IGHV4-61*02 F 866 88.24 195/221 nt 86.88 192/221 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*01 F 2 10 7 19 10.7.19 [1.17.38.11] CAREAPKTAGDSYGSLAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'C' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'A' (1 nucleotides at position 217 to 217 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagtagtggCtttttactactggagctggacccggcagcccgccgggCaagggactggagtggattgggcgtgtccatagcggtggtagttccgactacaacccctccctcacgggtcgagtcaccatcttagtggactcctccaagaatcagttctccctgaggctgacctctgtgacggccgcagacgcggccgtgtaAtttctgtgcgagagaagcgcccaagacagcaggtgattcctacggctctctcgctatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17220 JY8QFUQ01BCZ7N No results +17221 JY8QFUQ01C7436 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATSRGSANWYPFDHW in-frame - ctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17222 JY8QFUQ01ALJ94 productive Homsap IGHV3-7*01 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [0.17.38.11] CAGGRGWLIDYW in-frame + tggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17223 JY8QFUQ01CRELC productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 908 91.63 197/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame + cttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +17224 JY8QFUQ01CDWQU productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 677 80.19 170/212 nt 79.25 168/212 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [0.17.38.11] CVRDAETTVSGVAGWFDPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) ctggattcagctttagcGatttttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17225 JY8QFUQ01CXQQC productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 782 85.12 183/215 nt 84.19 181/215 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CATVRHLGERIFDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); tctctggggccaccatgagtagtttctactggagctgggttcggcagtccccagggaggggactggagtggattggatttGctttcttacagtgGggcccaccaactacagcccctccctcaagagtcgagtcaacttatcactggacgcggccaacaaacagttctctttgcagctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17226 JY8QFUQ01C3SES productive (see comment) Homsap IGHV3-66*02 F, or Homsap IGHV3-66*03 F 871 90.14 192/213 nt 89.67 191/213 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-25*01 F 1 8 7 11 8.7.11 [1.17.38.11] CARDGRGGDLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); tctgggttctccgtcagtttcaactacatgagctgggtccgccaggctccagggaaggGggctggagtgggtctcagttatctatgccgatggaagtacattctatgcagactccgtgaagggccgattcatcatctccagagacaattcaaagaacacgctcaatcttcaaatgaatagtttgagagttgacgacacggctgtgtattactgtgcgagagatgggcgcggcggtgaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17227 JY8QFUQ01A4SKX productive (see comment) Homsap IGHV1-2*02 F 858 89.25 191/214 nt 88.32 189/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*01 F 3 8 8 19 8.8.19 [0.17.38.11] CARDEANIEVVMTSNYYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'C' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); tggatacaccttcaccggccactatctacactgggtgcgacaggcccctggacaaggCacttgagtggatgggatgggtaaacatcaagagtggtggAcacaaattatccacagaagtttcacggcaggatcaccatgaccagggacacgtccatcaacacagccttcttagaagtgaccagcctgagatctgacgacacggccgtttattactgtgcgagagacgaggccaatattgaagtagtaatgacctctaattattattttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcancgcctgcctgggtccagggcttcttccccca +17228 JY8QFUQ01ABHA8 No results +17229 JY8QFUQ01DJKQL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGSYLYCFDYW in-frame - cctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtggtgatgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactgctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17230 JY8QFUQ01CDOKK productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1012 96.76 209/216 nt 95.83 207/216 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [2.17.38.11] CARGGGYYFVAIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'AG' (2 nucleotides at position 92 to 93 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaaAGtggggagcaccaactacaaccCcctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17231 JY8QFUQ01DER2Y No results +17232 JY8QFUQ01CB3MM productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1073 98.64 218/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARDRGPSSSSKMEYDYW in-frame + tctctggtggctccatcaacagtggtggttactactggagttggatccgccagcacccagggaagggcctggagtggattgggtacatctattacagtgggagtacctactacaacccgtccctcaagagtcgagttaccatatcagtagacacgtctaagaaccagttctccctgaagctgagctctgtgactgccgcggacacggccgtgtattactgtgcgagagatcggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17233 JY8QFUQ01AGXB8 productive Homsap IGHV3-21*04 F 963 94.01 204/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 163 76.79 43/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSHQVDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcgacttcagtagatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttgatagtaattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcgctgtttctgcaaatgaacagcctgagagccgatgacacggccgtgtattactgtgcgagagccgtgtcgcatcaggtggacgtctggggccaaggggccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17234 JY8QFUQ01BNG1R productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 82.79 178/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagccCcccagggaagggactggagtggattgGgggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc +17235 JY8QFUQ01CDU9L No results +17236 JY8QFUQ01B0NLO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKENYFESSGYHGMNVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcacctttaccaactatgccatgacctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtaatcgtggtactggagtgtactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagagccgaggacacggccctttattactgtgcgaaagagaattactttgagagtagtggttatcacggtatgaacgtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17237 JY8QFUQ01CXJM1 No results +17238 JY8QFUQ01A3934 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 9 7 12 9.7.12 [1.17.38.11] CAANLGHGSYFKYW in-frame - ctctggtgactccgtcagcagtgataactggtggagttgggtccgccagaccccagggaaggggctggagtggattggagaaatctatcatggtgggaccaccaactacaatccgtccctcaagggtcgagtcaccttatcggtcgataagtccaagaaccaattctctctgagaatgacctcttttaccgccgcagacacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17239 JY8QFUQ01DGW2D unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17240 JY8QFUQ01ALI2N unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 709 81.69 174/213 nt 80.75 172/213 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD2-15*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDWGGSFDRYYFDY## out-of-frame + Low V-REGION identity (81,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 51 of V-REGION: 'AG' (2 nucleotides at position 66 to 67 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); caccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactgggAGgtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtCccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccaggggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttnttcccccca +17241 JY8QFUQ01BGDI2 No results +17242 JY8QFUQ01DAQ0I productive Homsap IGHV3-48*02 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAKDRGGSAYPIFDYW in-frame - gcctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17243 JY8QFUQ01A9XAG unproductive Homsap IGHV3-7*01 F 967 94.44 204/216 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSGFYSTGY## out-of-frame + tctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17244 JY8QFUQ01ATZ5Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcanttccccgaaccggtgacggtgtgcgtggaactcag +17245 JY8QFUQ01B2M7V productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'T' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccTttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17246 JY8QFUQ01AJ2JB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttGatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17247 JY8QFUQ01AT6Y6 productive Homsap IGHV3-9*01 F (see comment) 789 84.55 186/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [2.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release agcctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17248 JY8QFUQ01AR7H6 productive (see comment) Homsap IGHV3-7*01 F 904 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.16.38.11] CAKARIYFYGSGSYSLFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 46 of V-REGION: 2 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) cctctggaatcaccttgagtccctattggatgacctgggtccgccaggctccggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17249 JY8QFUQ01DNNOD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17250 JY8QFUQ01C9C4P productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame - tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17251 JY8QFUQ01DAV2B productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17252 JY8QFUQ01BLY7O productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'TG' (2 nucleotides at position 35 to 36 in the user submitted sequence), (cause frameshift); tccggattcagtttcagtacttataacatgaattTGggtcccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17253 JY8QFUQ01A2D3K No results +17254 JY8QFUQ01C6ESZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGSYLYCFDYW in-frame + ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtggtgatgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactgctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17255 JY8QFUQ01BS8R3 No results +17256 JY8QFUQ01AX36U productive Homsap IGHV3-66*02 F 926 92.56 199/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 7 17 8.7.17 [1.17.38.11] CSTPTYCRGGSCSQIFDYW in-frame + cctctggattcaccgtcagtaactaccacatgaggtgggtccgccaggctccagggaaggggctggagtgggtctcagttatttacagcggtggtagtacatattacatagactccgtgaagggccgattcaccatctcgagagacgattccgagaacacagtgtatcttcaaatgaagagcctgagagctgaggacacggctgtatattactgttcgacgcccacatattgtaggggcggtagctgttcccagatttttgactattggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +17257 JY8QFUQ01CQUPT productive (see comment) Homsap IGHV3-48*02 F 874 89.04 195/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-8*01 F 3 8 8 11 8.8.11 [2.17.38.11] CAKVGKLYFFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGgtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagcacgaccataggctacgcagactctgtgaggggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggatagcctgagagacgaggacacggctgtgtatttttgtgccaaagtgggaaagttgtatttctttgaatactggggccggggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17258 JY8QFUQ01BVITE productive (see comment) Homsap IGHV3-66*02 F, or Homsap IGHV3-66*03 F 878 89.45 195/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-25*01 F 1 8 7 11 8.7.11 [2.17.38.11] CARDGRGGDLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); cagtgtctgggttctccgtcagGtttcaactacatgagctgggtccgccaggctccagggaaGggggctggagtGgggtctcagttatctatgccgatggaagtacattctatgcagactccgtgaagggccgattcatcatctccagagacaattcaaagaacacgctcaatcttcaaatgaatagtttgagagttgacgacacggctgtgtattactgtgcgagagatgggcgcggcggtgaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17259 JY8QFUQ01AOBLF No results +17260 JY8QFUQ01CV2CU productive (see comment) Homsap IGHV3-23*03 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [1.17.38.11] CARGAPFYDS (see Functionality comment) in-frame + Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagaagctatgccatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +17261 JY8QFUQ01ALXV8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame + ctctggattcaccttcagtcgctatagtatgaattgggtccgccaggctccagggaaggggctggagtggctcgcatacatcagtaggagtactaatgacatatactactcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttgtggggcctagggacagtggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +17262 JY8QFUQ01C2K0Q productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1007 96.74 208/215 nt 96.28 207/215 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARTTSSSGWYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggaggctccattagtaattactacCtggagttggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaatcagttcttcctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgaggactacttctagtagtggctggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17263 JY8QFUQ01BRA99 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [1.17.38.11] CANASPV*LE#YFYYYGMDVW out-of-frame - stop codons tctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctcccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17264 JY8QFUQ01CWO1D productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 112 64.52 40/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame + ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctccgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17265 JY8QFUQ01DDTC0 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1110 100.0 223/223 nt 99.1 221/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [2.17.38.11] CARSRTFYGSANYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'C' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); tgtctctggtCggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17266 JY8QFUQ01DBEAF productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 9 8.8.9 [1.17.38.11] CATRSQAMADW in-frame + ttcaggattcagcttcagttcctattggatgagttgggtccgccaggccccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagaaaaactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaggaactcgttgtttttggagatgagcagcctgagagccgaggacacggctgtctattactgtgccacgaggagtcaagccatggctgactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccccc +17267 JY8QFUQ01C1SB2 No results +17268 JY8QFUQ01AS6I7 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame + ctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +17269 JY8QFUQ01BK2LJ No results +17270 JY8QFUQ01CULNG No results +17271 JY8QFUQ01BFGR4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ6*01 F (see comment) 117 68.52 37/54 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [1.17.38.11] CANEVGYCSG## out-of-frame + Other possibilities: Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtgggggggccaggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +17272 JY8QFUQ01AS7OK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKCKAPGKVDWFDPW in-frame + cctctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctggtaaggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +17273 JY8QFUQ01BXGWV No results +17274 JY8QFUQ01CE17X productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17275 JY8QFUQ01B62EW No results +17276 JY8QFUQ01CW34D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-20*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGLTTMTGNGLEHW in-frame + ctctggtttcacctttagtagtcatgccatgacctgggtccgccaggctccggggaaggggctggagtgggtctcatcttctaacagtagtgatgaatccacatactatgcagactccgtgaagggccgcttcaccatttccagagaccattccaagaacacggtgtttttgcaaatgtacagcctgagagccgaagacacggccctctattactgtgcgagagggctaacaacaatgacagggaatggtcttgagcactggggccagggagccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca +17277 JY8QFUQ01CN0DI productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag +17278 JY8QFUQ01B7JCR productive (see comment) Homsap IGHV3-9*01 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcaactttaataattatgccatgcactGgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17279 JY8QFUQ01C1V49 productive Homsap IGHV4-61*02 F 816 85.45 188/220 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD5-24*01 ORF 1 10 7 14 10.7.14 [1.17.38.11] CARGMATIKTVRFDPW in-frame + ctctggtggctccatcaggagcggaattaattcctggacatggatccggcagcccgccgggaagggactggagtgggttgggcgtatttacgtcaatggagacaccaactacaacccctccctcaagagtcgggccagcatatcaatggacacgtccaagaaccagttttccctgcagttgacctctgtgaccgccgcagattcggccgtctattattgcgcgagagggatggctacaataaagacggtccgattcgacccctggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +17280 JY8QFUQ01BU0AH unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17281 JY8QFUQ01A1MJG productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 903 91.59 196/214 nt 91.12 195/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 1 8 7 17 8.7.17 [1.17.38.11] CARVVMATVYTGSYYFDDW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); gtatggtgggtccttcagtgataactcctggacctggatccgccagcCccccagggaaggggctggagtggattggagagatcaatcatagtggaaacaccaactacaacccgtccctcaggagtcgagtaatcatgtcaatagacacgtccatgaaccaattctccctgaagctgacttctgtgaccgccgcggacacggctgtgtattattgtgcgagagtcgtgatggctacagtttatactgggtcctactactttgacgactggggccagggaaccctggtctccgtcttctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcatcgcctgcctggtcagggcttcttccc +17282 JY8QFUQ01BRQMG productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 970 91.34 211/231 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 10 9 19 10.9.19 [3.17.38.11] CARASRRDRQSDRNYYELDFW in-frame - catctacccggggacagtgtctctagcaacagtgccacttggaactggatcaggcagtccccaacgggaggccttgagtggctgggaaggacatcctacaggtccaaatggtatagtgattatgcggtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcaattgaactccgttagtcccgaggacacggctgtgtattactgtgcaagagcttccagacgcgatcgtcagtctgatcggaactactatgagctggacttctggggccagggaatcttggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17283 JY8QFUQ01AIAUG productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.49 197/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtCgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17284 JY8QFUQ01CWH7Q productive (see comment) Homsap IGHV4-61*02 F (see comment) 779 84.4 184/218 nt 83.03 181/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 9 7 13 9.7.13 [1.17.38.11] CARAKDHDDYLVDPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 37 of V-REGION: 'CTT' (3 nucleotides at position 28 to 30 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 3 nucleotides (from position 27 in the user submitted sequence), (do not cause frameshift) tctctggtgcctccatcactagtggtaCTTactactggagttggttccggcagcccgccgggaagacactggaatgggttgggcgtatctatacaactgggagcacctattacaaTcccctctctcaaaagccgagtcaccgtttcagtcgacgagtcccagaatcagctcttcctggacctgacttctgtgaccgccgcggacacggccgtctacttctgtgcgcgagctaaggaccacgatgactacctggtcgacccctggggccaggggatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17285 JY8QFUQ01CYV4I unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 99 59.72 43/72 nt 7 X X 7.X.X [X.17.X.X] null - No rearrangement found ttcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17286 JY8QFUQ01CEQHK productive (see comment) Homsap IGHV3-7*01 F 1044 98.16 213/217 nt 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggGggctggagtgggtggccaacataaaggaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17287 JY8QFUQ01DO8DA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 925 92.96 198/213 nt 91.55 195/213 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [X.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'CC' (2 nucleotides at position 85 to 86 in the user submitted sequence), (cause frameshift); ggattcaTcgttcagtagctactggatgcactgggtccgccaagctccagggaagGgggctggtgtgggtgtcacgtagtaataCCggggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17288 JY8QFUQ01CO3DK productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 929 91.4 202/221 nt 90.95 201/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtgataatttctactggggctggatctgccagcccccagggaagggactgcagtggattgGggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17289 JY8QFUQ01BY42Y unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 406 82.35 98/119 nt 8 8 X 8.8.X [1.17.5.X] null + No rearrangement found Low V-REGION identity (82,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgtttctacttacaccattttctacgcagagtctg +17290 JY8QFUQ01CVFZZ productive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17291 JY8QFUQ01CH5XG productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17292 JY8QFUQ01AU604 productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDGYYYYHSGMDVW in-frame + gctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattattgtgcgaaagacggctattattattatcacagcggtatggacgtctggggccaagggaccacggtcatcgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +17293 JY8QFUQ01B4JEZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'CGC' (3 nucleotides at position 36 to 38 in the user submitted sequence), (do not cause frameshift); cctctggattcacctttagcacctatgccatgagaCGCtgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17294 JY8QFUQ01AQDHE productive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17295 JY8QFUQ01BRIHD productive Homsap IGHV3-7*01 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - ggctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +17296 JY8QFUQ01A72N8 productive Homsap IGHV3-23*05 F (see comment) 447 83.08 108/130 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 X 5 16 X.5.16 [X.X.38.11] CVRYDYSRLHRSNYFGPW in-frame + Low V-REGION identity (83,08% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcatcagttatgactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga +17297 JY8QFUQ01A2PAK unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ1*01 F 89 63.46 33/52 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaaggggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag +17298 JY8QFUQ01BPHS4 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CXKRLSGRPLVESGAP#FFDDW out-of-frame + stop codons cctctggattcacctttagcgactatggcatgagttgggtccgccaggctccagggaagggactggagtgggtctcaagtattatcgctaatggtggtgacacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagatgaacagccttagaggcgaggacacggccgtatattattgtncgaaaagactatccggacggccgcttgttgaatcaggtgcgccccttctttgacgactgggaccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17299 JY8QFUQ01CYQ3S No results +17300 JY8QFUQ01A4YVV productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [0.17.38.11] CAARIDSGHYWNAFDIW in-frame + tggatacagtttcaccaactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctggtgactctgatacccggtacaacccgtccttccaaggccaggtcaccttctccgtcgacaagtccatcaacaccgcctacttgcagtgggacagcctgaagacctcggacaccgccaagtattactgtgcggcgagaattgatagtggtcattactggaatgctttcgatatatggggccaagggacgatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +17301 JY8QFUQ01AWHX3 No results +17302 JY8QFUQ01CRBFS productive (see comment) Homsap IGHV4-59*03 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 89 to 94 in the user submitted sequence), (do not cause frameshift); ctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17303 JY8QFUQ01B8C40 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17304 JY8QFUQ01AEURC No results +17305 JY8QFUQ01C70N2 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 657 77.88 169/217 nt 76.96 167/217 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.16.38.11] CAREDIVREGLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (77,88% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tgtctggtggctccatcgccacttatcattggtggAacttgggtccgccagaccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaatccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17306 JY8QFUQ01ARHX6 productive Homsap IGHV3-9*01 F 806 85.78 187/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDRKGSNWYYFENW in-frame + cctctagattcacctttaatggttactggatgagttgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17307 JY8QFUQ01BXMGR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17308 JY8QFUQ01AGDPV productive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17309 JY8QFUQ01ASWON productive Homsap IGHV4-39*02 F 866 88.24 195/221 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 10 7 17 10.7.17 [1.17.38.11] CARQMGYSGSGLSVWFDPW in-frame + tctctggaggctccatcaacactaatcgttactactgggtctggtttcgccagcccccggggaaggggctggagtggattgggactatttattatactgggatcaccaactacaatccattcttcaagagtcgagtcaccatgtccgtagacacgtccagccaccacttctccctgaggttgagctctgtgaccgccgcagacacggctgtctactactgtgcgagacaaatgggatactctggttcggggctcagtgtgtggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggttttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +17310 JY8QFUQ01AX55X productive (see comment) Homsap IGHV3-49*04 F (see comment) 804 84.75 189/223 nt 83.86 187/223 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD3-3*01 F 2 8 9 16 8.9.16 [1.17.38.11] CARDRDYHDSWPDSFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 88 in the user submitted sequence), (cause frameshift) cttctggattcaccttaggtgattattgtctaatgtgggtccgacagtttccaGgggaagcgactggagtgggtaggcttcattagaatgcactttttggtgggaccacagaatacgccgcgtctgtgaaaggaagattcaccatctcaagagatgactccgagggcatcgcccacctagagatgaacagtctcaacaccgaggacacagccgtgtattattgtgctagagaccgcgattatcacgatagttggcccgattcttttgatgtctggggcccagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17311 JY8QFUQ01BK51A productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.16.38.11] CAKGIVGASMQADWFHPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcgtctttggcgactatgcgatgagctgggtccggcaggctccagggaggggcgtggagtggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17312 JY8QFUQ01BHE4G productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 809 86.51 186/215 nt 86.05 185/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-16*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARCKSAGLVDWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcagcattagcgactatgccatggcctgggtccgccaggctccagggaaggggccggagtgggtctcaagtgttactaatggttttggcacatactacgcagactctgtgaagggccggttcaccgcctccagagacaattccaagaacgcattgttcttggaaatgaacatcctcagagccgaggacacggccgtatattattgtgcgaggtgtaagtcggccggtttggtggactggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17313 JY8QFUQ01DMKXA productive (see comment) Homsap IGHV1-3*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [0.16.38.11] CATGLCGTACYLLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) tggatacaccttcactaactatcccatacattgggtgcgccaggccccggacaaaggcttgagtggatgggattgatcagcgctggcaatgataacacaagattttcacagaagttccagggcagagtcaccattaccagggacacagccgcgaacacagcctacatggagttgagcagcctgacatctgaagacacggctgtgtactactgtgcgacaggcctctgcggtactgcctgctatctgcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17314 JY8QFUQ01B06KG unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARLGATR##DYW out-of-frame + stop codons ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttggggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctcccaccaacgggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctcggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17315 JY8QFUQ01BJOAR productive Homsap IGHV3-7*01 F 882 89.86 195/217 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD4-23*01 ORF 3 8 8 12 8.8.12 [1.17.38.11] CARGTSVDPGIDHW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtaattattggatgcactgggtccgccaggtttcagggaggggcgtggagtgcgtggccaccataaacgaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactctctgtttttgcagatgaacagcctgagagccgaggacacggctgtctactactgtgcgagagggacctcagtggacccggggattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17316 JY8QFUQ01BHYT1 No results +17317 JY8QFUQ01A33HU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17318 JY8QFUQ01AZMST unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 987 94.55 208/220 nt 94.09 207/220 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.16.38.11] CARRGRCG*#YWYFDLW out-of-frame - stop codons in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctagtgactccatcagcagtactaattactactggggctggatccgccagccccagggaaggggctggagtggattgggagtatgtatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgagacgggggagatgcggataactactggtacttcgatctctggggccgtggcaccctggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17319 JY8QFUQ01BLS2S productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 945 93.09 202/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'CC' (2 nucleotides at position 88 to 89 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 77 of V-REGION: 'A' (1 nucleotides at position 138 to 138 in the user submitted sequence), (cause frameshift); ctctggattGcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaataCCggggggggactgacacagcctacgcggactccgtgaagggccgattcaAccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc +17320 JY8QFUQ01AU7VX productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17321 JY8QFUQ01DBBUF unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 917 92.09 198/215 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD5-24*01 ORF 3 8 7 X 8.7.X [1.17.38.11] CARRGRCG*#YWYFDLW out-of-frame + stop codons tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgagacgggggagatgcggataactactggtacttcgatctctggggccgtggcaccctggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +17322 JY8QFUQ01BIF8K productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17323 JY8QFUQ01BI0YI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17324 JY8QFUQ01AAXLX No results +17325 JY8QFUQ01ALDS2 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 142 76.0 38/50 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDTLEVVSNMDDA#FDLW out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcattttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17326 JY8QFUQ01AZBA5 No results +17327 JY8QFUQ01DQVX4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDTITMGGDVAPLFDYW in-frame + ctctggattcacctttagtaactatgacatgggctgggtccgccaggctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +17328 JY8QFUQ01BQYYZ No results +17329 JY8QFUQ01A1V61 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 X 10.7.X [1.17.38.11] CARRWASNGWSW#YFDYW out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtGactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgagcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17330 JY8QFUQ01AVTO1 unproductive (see comment) Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons tctggagttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17331 JY8QFUQ01DJ1Y1 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [2.17.38.11] CAKDLFQVSTTYFDYW in-frame - gcctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17332 JY8QFUQ01C9LX0 productive Homsap IGHV3-30*01 F 883 89.5 196/219 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [2.17.38.11] CACGHMRDGYDVW in-frame - gcctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17333 JY8QFUQ01C5F9U No results +17334 JY8QFUQ01B08DF productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 15 10.7.15 [1.17.38.11] CARNPSYSNSHQHCDYW in-frame + tctctggtgcctccatcaacagtggtagttactactggagttgggttcggcagcccgccgggaagggactggagtggattgggcgtatctacaccagtgggagcaccaactacaacccctccctcaagagtcgagtcgccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctatttttgtgcgagaaatccctcttatagcaattcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17335 JY8QFUQ01DMHMQ productive (see comment) Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 743 82.49 179/217 nt 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 3 9 7 15 9.7.15 [1.17.37.11] CARVWVAGSRDENFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 30 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 162 in the user submitted sequence), (cause frameshift) ctcgggtggttccatgacgagtactaattctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgacctgtcattagacgcgtctaataatgtttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17336 JY8QFUQ01CKNQR productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17337 JY8QFUQ01BPX0B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcanttccccgaaccggtgacggtgtgcgtggaactca +17338 JY8QFUQ01BRXZI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 922 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); ctctggattcacctttagccCactttgccgngacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17339 JY8QFUQ01CJGDZ No results +17340 JY8QFUQ01A0JNN No results +17341 JY8QFUQ01AWIXW productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaactc +17342 JY8QFUQ01A5UU6 unknown (see comment) Homsap IGHV4-61*02 F 884 89.14 197/221 nt 88.69 196/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgGggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttcggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc +17343 JY8QFUQ01CA8IW productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'T' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); cctctggaGttcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatTgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17344 JY8QFUQ01DH7MJ unproductive (see comment) Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [1.17.38.11] CARPAGAG*PFFA#YYSGLDVW out-of-frame + stop codons ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggcagggtgacccttttttgccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactca +17345 JY8QFUQ01CKLBU productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); ttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17346 JY8QFUQ01ADEKS No results +17347 JY8QFUQ01CGSFP unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKYVEGVVIYGGLL##SYAMDVW out-of-frame - in FR3-IMGT at codon 70 of V-REGION: 'A' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); ttctggattcgcctttagccgttatgccatgacttgggtccgccagactccagggagggggctggagtgggtctcaggtctcagtggtagtggtgatagcacatactactcaaacAtccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggagggggtggtcatatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17348 JY8QFUQ01BOB7M No results +17349 JY8QFUQ01A33TY productive (see comment) Homsap IGHV4-61*02 F 957 92.38 206/223 nt 91.93 205/223 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [2.17.38.11] CATVARRGAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 95 of V-REGION: 'G' (1 nucleotides at position 195 to 195 in the user submitted sequence), (cause frameshift); gtcgtctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgaGcccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcagccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17350 JY8QFUQ01ASDDF productive Homsap IGHV4-61*02 F 961 92.79 206/222 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [2.17.38.11] CATVARRGAFDIW in-frame - tcgtctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17351 JY8QFUQ01CLDVV productive Homsap IGHV3-30*04 F, or Homsap IGHV3-30-3*03 F 900 90.32 196/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame - ctctggattcaccttcagaagttctgcccttcactgggtccgccaggctccaggcaagggcctggagtgggtggcagtaacatcatatgatggaggtgataaatcctacgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgctatatctgcgaatgactaacctgagacctgaggacacggctgtctattactgcgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17352 JY8QFUQ01AX1CJ productive Homsap IGHV3-11*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggcccttgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17353 JY8QFUQ01DIDF7 No results +17354 JY8QFUQ01C7A43 No results +17355 JY8QFUQ01A83TT productive (see comment) Homsap IGHV3-11*01 F 838 87.21 191/219 nt 86.76 190/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-7*01 F 1 8 8 15 8.8.15 [2.17.38.11] CVRESRSWTGSTLPAYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtgactattacatgagttggtaccgccaggctccaggtcaggggctggagtggctttcatatataagtcaaactggCgaaaaccacatacttcgcagactctgtgaagggccgattcaccatctccagggacaatgccaagacatcagtgtttctgcaaatgaacagcctgagagttgacgacacggccgtgtatttttgtgtgagagaatctaggagttggactggaagtacacttccagcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17356 JY8QFUQ01CCZ9F No results +17357 JY8QFUQ01CHKDL unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 877 89.81 194/216 nt Homsap IGHJ2*01 F (see comment) 76 60.38 32/53 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGFV# out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggtttcgtggggccagggagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17358 JY8QFUQ01BB0FV unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYFGTL#DYW out-of-frame + stop codons ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttggaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17359 JY8QFUQ01C2RIZ productive Homsap IGHV3-74*03 F 914 91.28 199/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKVDNDGWHGTIDRW in-frame + cctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggataacgatggctggcacggaacaatagaccgctggggccagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +17360 JY8QFUQ01BT8ZF unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANYW# out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +17361 JY8QFUQ01CCQ01 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17362 JY8QFUQ01CR8IO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 775 84.02 184/219 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD2-8*01 F 3 8 8 20 8.8.20 [2.17.38.11] CAKGASTAVMVSGTDCYGLDVW in-frame - Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaggggactggagtgggtcgcaactataagtggtggaggttatagtatatatgacgcagactccgtgaagggcaggttcaccatctccagagacaactccaagaccaccttgtttctggaaatgaaaagtctgagagtcgatgatacggccgtctattactgtgcgaaaggggcctcgactgcagtaatggtgtctggaacagattgttacggtttggacgtctggggccacgggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +17363 JY8QFUQ01COIAZ productive (see comment) Homsap IGHV3-48*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.37.11] CAKDRGGSAYPIFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 2 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) tctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccagactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17364 JY8QFUQ01C759P productive Homsap IGHV1-8*01 F 948 93.93 201/214 nt Homsap IGHJ1*01 F 188 84.62 44/52 nt Homsap IGHD4-23*01 ORF 2 8 8 13 8.8.13 [0.17.38.11] CARGSLDYGGLPQHW in-frame + tggatacaccttcaccagttatgatatcaactgggtgcgacaggccgctggacaagggcttgagtggatgggatgggtgaaccctaatagtggtgccacaggctatgcacagaagttccagggcagagtcaccatgagcagggacacctccgaaagtacagcctacgtggagctgagcagcctgggatctgaggacacggccgtgtatttctgtgcgagaggctccctggactacggtggcctcccccagcactggggccagggcaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17365 JY8QFUQ01AOAKY No results +17366 JY8QFUQ01BV17P No results +17367 JY8QFUQ01A0ESJ productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggGcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17368 JY8QFUQ01CCA5W productive (see comment) Homsap IGHV3-48*01 F (see comment) 744 83.89 177/211 nt 83.41 176/211 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [0.17.38.11] CSRDGRRGYDLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,89% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 80 in the user submitted sequence), (do not cause frameshift) tggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17369 JY8QFUQ01CX4H6 productive (see comment) Homsap IGHV1-3*01 F 899 91.16 196/215 nt 90.23 194/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); ctggatacagcttcactaactacaatatccattgggtgcgccaGggcccccggacaaaGggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17370 JY8QFUQ01CQ9WN productive Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17371 JY8QFUQ01AB3KI productive (see comment) Homsap IGHV3-11*01 F 862 89.67 191/213 nt 89.2 190/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17372 JY8QFUQ01C1CZW productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame - ttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +17373 JY8QFUQ01BRPY0 No results +17374 JY8QFUQ01CO1A1 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 1004 95.87 209/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPAGGSGAYEYW in-frame - cctctggattcaagtttgatgattccggcatgagctgggtccgccaagctccagggaaggggctggagtgggtctctggtattaattggaatggtggtaagacaggttatggagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatttgcaaatgaacagtctgagagccgaggacacggccttgtattactgtgcgagaggccccgccgggggatctggcgcatatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +17375 JY8QFUQ01ALEO5 No results +17376 JY8QFUQ01C6ZIX No results +17377 JY8QFUQ01A44PN productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1073 98.64 218/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARDRGPSSSSKMEYDYW in-frame + tctctggtggctccatcaacagtggtggttactactggagttggatccgccagcacccagggaagggcctggagtggattgggtacatctattacagtgggagtacctactacaacccgtccctcaagagtcgagttaccatatcagtagacacgtctaagaaccagttctccctgaagctgagctctgtgactgccgcggacacggccgtgtattactgtgcgagagatcggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17378 JY8QFUQ01CLFVV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 874 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [2.17.38.11] CAKDASRYYYNSYCDNW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 213 to 213 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttaCtttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17379 JY8QFUQ01AR39G unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 867 89.72 192/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - aggattcaccttcagtaggtactggatgcactgggtccaccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17380 JY8QFUQ01BMQ8K productive Homsap IGHV3-7*01 F 939 93.46 200/214 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARVRGYYGGQYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17381 JY8QFUQ01DI3XP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame + ctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +17382 JY8QFUQ01B4V0J unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 639 76.96 167/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (76,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17383 JY8QFUQ01A3QU6 productive (see comment) Homsap IGHV3-69-1*01 P (see comment) 1011 97.2 208/214 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01A3QU6 ; 7 AA in Homsap_IGHV3-69-1*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17384 JY8QFUQ01DCAL1 productive Homsap IGHV3-9*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + cctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17385 JY8QFUQ01B8GAC No results +17386 JY8QFUQ01BIGUV No results +17387 JY8QFUQ01BSQSD productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17388 JY8QFUQ01C1XOG No results +17389 JY8QFUQ01CS77U unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P 121 54.48 73/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons ctctggattcatcttcagtgactactacatgacctggatccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17390 JY8QFUQ01B757D productive Homsap IGHV4-61*02 F (see comment) 569 73.3 162/221 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARECSNSKVGPRALDSW in-frame + Low V-REGION identity (73,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) tttctggtggcccgatcaaaagtcctgattaccattggacgtggatccggcaggccgccgggaaggggctggagtgggtcgggcgtgtctatatgactggctatgtcgagaacaatccatccctctccgggcgtctctccatgtcgattgacacggcgaagaatcagttttctatgacattgacttctgtgaccgccgcagacacggccctttatttttgtgcgagggagtgtagtaattcgaaagtcggaccgagagcgcttgactcctggggcccgggaagtctggtcaccgtatcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17391 JY8QFUQ01AQ8HA No results +17392 JY8QFUQ01BG2MU unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +17393 JY8QFUQ01AR97Q No results +17394 JY8QFUQ01BR1B9 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 124 72.0 36/50 nt Homsap IGHD2-15*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDPRDYCSGGYCFVGAFDI## out-of-frame - tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctgggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17395 JY8QFUQ01B5WEN productive (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P (see comment) 728 82.33 177/215 nt Homsap IGHJ6*02 F (see comment) 211 82.26 51/62 nt Homsap IGHD6-6*01 F 1 8 8 21 8.8.21 [1.17.38.11] CAKDLGYSISSGASTHYYGMGVW in-frame - however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01B5WEN ; 7 AA in Homsap_IGHV3-69-1*01), and low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (highest number of consecutive identical nucleotides) cctctggattcgcttttggtgactatgccatgaactgggtccgccaggctccagggaggggcctggaatgggtctcatttgtcaccactactggcagttccacatattatgcagactccgtgaagggccgattcaccgtttccagagacgacgccaagaatctactgtatcttcagatgaccggcctgagagacggggacacggctacatattactgtgcgaaagacttggggtacagcatctcgtcgggggcctccacgcactactacggaatgggcgtctggggccaagggacaacggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17396 JY8QFUQ01AKOA9 productive Homsap IGHV4-61*02 F 924 91.36 201/220 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARAWNGDYEVGWFDPW in-frame - ctctggtgactccatcggtaatggaagttactactggagctgggtccggcagtccgccgagaagggactggagtggattggacatatctataccagagggagcaccaactacaacccctccctcaagagtcgagtcaccatttcagccgacacgtccaagaatcagatctccctgaagttgacctctgtgaccgccgcagacacggccgtatattactgtgcgagggcgtggaacggtgactacgaggtgggctggttcgacccctggggccaggggaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17397 JY8QFUQ01B63VT unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [2.17.38.11] CAKGGW*R##LDYW out-of-frame - stop codons in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) gtgtctgggttaaccttcagtgaggatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagtcattggaacaatggaaagacctttcactatgcagactccgtgaagggccgcttcgtcatctcccgagacaattccaagagcaccctatatttacaaatgaatagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17398 JY8QFUQ01CH5Y6 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD3-16*01 F 1 8 7 X 8.7.X [2.17.38.11] CGTSSRAWGADAFD#LG out-of-frame - Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); agcctctgggctcagcgtcagtaactaccgcatggGgctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagagatgatagtacagatcatgtagattccgtgaagggccgattcaccgtttcccgagacaattccaagaacacattgtaccttcagatgaacagtgtgacagccgaggacacgaccgtttattattgtggaactagttcccgcgcctggggcgctgatgcctttgatatctgggggccagggggacactggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17399 JY8QFUQ01DT4RJ productive Homsap IGHV3-7*03 F 851 88.07 192/218 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctccggattcatttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgccctggtccaggggcttcttcccccca +17400 JY8QFUQ01A3GBW No results +17401 JY8QFUQ01B52AE productive Homsap IGHV3-7*01 F 882 89.86 195/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +17402 JY8QFUQ01B9B4O unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt 97.33 219/225 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 1 10 9 X 10.9.X [1.17.38.11] CTRGSSRGGRYDENYYELDF## out-of-frame - in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 151 to 151 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacCccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17403 JY8QFUQ01A68J9 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1030 97.69 211/216 nt 97.22 210/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17404 JY8QFUQ01ADEWV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CANEVGYCSGG# out-of-frame + ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtgggggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +17405 JY8QFUQ01B5BSI No results +17406 JY8QFUQ01CAL5B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-17*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKEMIRYGDDVFGGLNVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggatttacctttagcagttatgccatgaactgggtccgccaggctccagggaaggggctgcagtgggtctctggtattagtggtggtggtgatgacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtgtattactgtgcgaaagaaatgatccgctacggggacgacgtttttggcggtctgaacgtctggggccaagggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +17407 JY8QFUQ01AECSW unknown (see comment) Homsap IGHV3-23*05 F 102 55.24 58/105 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons cctctggattcgtctttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17408 JY8QFUQ01DBCLU productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 901 90.41 198/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [2.17.38.11] CVSDLAGQKGFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 172 to 172 in the user submitted sequence), (cause frameshift); gcctcaggattcaccttcagtaggtactggatgcactggGgtccgccaagttccagggaaGggggccggtgtGgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgTtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctccgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17409 JY8QFUQ01BVZI4 unknown (see comment) Homsap IGHV3-72*01 F 106 53.44 70/131 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons ctctggattcaccttcagtgaccactacatggactgggtccgccaggccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +17410 JY8QFUQ01DJPGW unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 785 84.16 186/221 nt 82.35 182/221 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD4-17*01 F 3 10 7 X 10.7.X [1.17.38.11] CARRWAATAGHGLL*LL# out-of-frame - stop codons Low V-REGION identity (84,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 28 of V-REGION: 'AC' (2 nucleotides at position 11 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'GA' (2 nucleotides at position 72 to 73 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift); tctctggtggACtcccatcagtagtactcattactattggGggctggatccggcaggcccccagggaggggGActggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccCctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcggcaacggctggtcatggactactttgactactgggggccagggaatcgtggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17411 JY8QFUQ01A2V18 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDNYGDYW# out-of-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17412 JY8QFUQ01B51EH productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 894 91.12 195/214 nt 90.19 193/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD5-18*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVGEQMIDAVSHNYAMDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'CATCAA' (6 nucleotides at position 19 to 24 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagCATCAAtacttacttctggagttggatccggcagcccccagggaagggactggagtggattgggtatatctctcacagtgggagtgccaactacaaccCcctccctcgagagtcgagtcaccatcttaagagacacgtccaagaaccagttctctctgaggctgagggctgtaaccgcggcggacacggccgtgtatttctgtgtgggggaacagatgattgacgcagtctcccacaactatgccatggacgtctggggccaagggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +17413 JY8QFUQ01AW4KK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17414 JY8QFUQ01BQHEK No results +17415 JY8QFUQ01BOC8J No results +17416 JY8QFUQ01B3E1A productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgCtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17417 JY8QFUQ01BYXM8 No results +17418 JY8QFUQ01DSHPL productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 855 88.48 192/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame + ttctggattcagtcctaccgatttttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17419 JY8QFUQ01AYWUO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1035 97.7 212/217 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGPHQYYFDY## out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactactttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17420 JY8QFUQ01BW9QL productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17421 JY8QFUQ01AZOKF No results +17422 JY8QFUQ01B4NOB unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +17423 JY8QFUQ01DFP0A unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 724 81.48 176/216 nt 81.02 175/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (81,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT at codon 84 of V-REGION: 'C' (1 nucleotides at position 154 to 154 in the user submitted sequence), (cause frameshift); tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccCaagaacacactatatctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17424 JY8QFUQ01ABQTA unproductive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDDYGVFDS## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtggctattggatgagttgggtccgccaggctccggggaagggtctggagtgggtggccaacatagagaaagatggaagtgacataaagtatgtggactctctgaagggccgattcaccatctccagagacaacgccaagaattcactgtatctggaaatcaacagcctgagcgacgaggacacgtctgtgtattactgtgcgagagatgattacggcgtctttgactcctggggcccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaaggtcttccccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +17425 JY8QFUQ01CR3KB unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +17426 JY8QFUQ01A7240 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 969 93.64 206/220 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-14*01 ORF 1 10 7 9 10.7.9 [1.17.38.11] CAAGTVLFDYW in-frame + ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagtatctattacagtgggagcaccttctacaacccgtccctcaagagtcgagtcaccatatccgtagacatgtccaggaaccagttctccctgaaaatgaagtctgtgaccgccgcagacacggctgtgtattactgtgccgccggcacggtcctctttgactactggggccacggaaacatggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17427 JY8QFUQ01BP7G7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame + cctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17428 JY8QFUQ01AMWMT productive (see comment) Homsap IGHV3-48*02 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDRGGSAYPIFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggGggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +17429 JY8QFUQ01CATW3 No results +17430 JY8QFUQ01CBB71 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - tctggaattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17431 JY8QFUQ01CO7CD productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKEEFDTGWTQPGDW in-frame + cctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactgggaccagggaacgctgatcaccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagccctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttccccca +17432 JY8QFUQ01CUPRA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKENYFESSGYHGMNVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcacctttaccaactatgccatgacctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtaatcgtggtactggagtgtactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagagccgaggacacggccctttattactgtgcgaaagagaattactttgagagtagtggttatcacggtatgaacgtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17433 JY8QFUQ01BP8ET productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17434 JY8QFUQ01DW83E No results +17435 JY8QFUQ01BPU4M productive (see comment) Homsap IGHV4-61*01 F 978 94.09 207/220 nt 93.64 206/220 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGAYWNLIRDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 67 of V-REGION: 'TATAATCCCCTG' (12 nucleotides at position 110 to 121 in the user submitted sequence), (do not cause frameshift); ctctggtggctccgtcagcagagatatttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatgtatcacagagggaacactaagTATAATCCCCTGtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtgggtccggtggggcctactggaatttgatccgggactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17436 JY8QFUQ01AODKD No results +17437 JY8QFUQ01AU4JA productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 82.79 178/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctgGgattcggcagcccccagggaagggactggagtggattgGgggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17438 JY8QFUQ01A8VWO unknown (see comment) Homsap IGHV3-74*03 F 126 54.81 74/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgcggtcatcgcctgcctggtccagggcttcttccccca +17439 JY8QFUQ01A1P86 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 915 90.91 200/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - agcctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17440 JY8QFUQ01CD3BX productive Homsap IGHV3-7*03 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame - cctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +17441 JY8QFUQ01A2JAS productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F (see comment) 671 78.44 171/218 nt 77.52 169/218 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [2.16.38.11] CAREDIVREGLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (78,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gtgtctggtggctccatcgccacttatcattggtggAacttgggtccgccagaccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17442 JY8QFUQ01C2FWS unproductive Homsap IGHV3-7*01 F 917 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-3*02 F 3 7 8 X 7.8.X [1.17.38.11] CARGSYWHYDTFGDY#W out-of-frame - in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) ctctggatttacttttacaactattggatgacctgggttcgccaggntccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactatttggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17443 JY8QFUQ01C7QDY No results +17444 JY8QFUQ01AV6MQ productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17445 JY8QFUQ01CI50M No results +17446 JY8QFUQ01BJBWT productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 954 93.55 203/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 14 8.8.14 [1.17.38.11] CATDRKYSGVRGDDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcaggaactatgctatgcactgggtccgccaggctcctggcaaggggctagaatgggtggcttttatatcatatgatggaagtagtcaatactacgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacactttatctgcaaatgaacagcctgagaggtgacgacacggctgtgttttactgtgcgacggaccggaaatatagtggtgtacgaggcgatgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +17447 JY8QFUQ01AW35M unknown (see comment) Homsap IGHV4-61*02 F (see comment) 350 67.46 114/169 nt 10 7 X 10.7.X [0.17.21.X] null - No rearrangement found Low V-REGION identity (67,46% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggtggctccatcagcagtgatgattactactggagctggatacggcagtccgccgggaagggactggagtggattgggcgaatttataaaagtggcgacacagtgtacaacccctcccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17448 JY8QFUQ01CI80K productive (see comment) Homsap IGHV2-5*02 F 1179 98.36 240/244 nt 96.72 236/244 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 3 10 7 15 10.7.15 [9.17.38.11] CAQKGEIDTYGPKYDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 42 of V-REGION: 'C' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 185 to 185 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttctctgggttctcactcagcactagtggagtgGggtgtgggctggCatccgtcagGcccccaggaaaggccctggagtggcttgcactcatttattgggatgatgataagcgctacagtccatctctgaagagcagactcaccatcaccaaggacacctccAaaaaaccaggtggtccttacaatgaccaacatgaaccctatggacacagccacatattactgtgcacagaagggggaaatagacacctatggccccaaatatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17449 JY8QFUQ01BOGW2 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 826 86.04 191/222 nt 85.59 190/222 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [2.17.38.11] CVRHVRRFWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctctaatgggctccatcagcCggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17450 JY8QFUQ01CWQZU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-21*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtttattactgtgcgagaggccgaatagtgtcggttggtatgtcaggctggttcgacccctggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagccctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttcccc +17451 JY8QFUQ01BXMUH unproductive Homsap IGHV3-7*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [1.17.38.11] CARGSYWHYDTFGDY## out-of-frame + in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaAaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattgggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtgggaactcag +17452 JY8QFUQ01A723I productive (see comment) Homsap IGHV3-7*01 F 981 94.93 206/217 nt 94.01 204/217 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-3*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDDDFWNGKHFDPW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 86 in the user submitted sequence), (cause frameshift) cctctggattcacctttagcaactatgccatgagctgggtccgccaggctccagggAaaggggctggagtgggtggccaatataaaaaagatggaagtgagaaatactatgtggactctgtgaagggccgtttcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagaggcgaggacacggctgtgtatcactgtgcgagagacgacgatttttggaatggtaaacacttcgacccctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17453 JY8QFUQ01BZ1GY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +17454 JY8QFUQ01B5QF3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17455 JY8QFUQ01DDDB8 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag +17456 JY8QFUQ01CANL1 productive Homsap IGHV3-9*02 F 896 90.37 197/218 nt Homsap IGHJ6*02 F 109 66.07 37/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + cctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagnacccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga +17457 JY8QFUQ01AV2J9 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 937 92.24 202/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gcctctggatcaccctttggttattGatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17458 JY8QFUQ01BBSRC productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ3*01 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-16*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARTYTYRNAFDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 34 of V-REGION: 'ACC' (3 nucleotides at position 21 to 23 in the user submitted sequence), (do not cause frameshift); tctttggtgactctctgagtACCagtagcagtttctactggggctgggtccgccaggccccagggaagggactggagtgggttgggactgtttattatagtgggagcgcccactacaatccgtccctcaagagtcgagtcgccatatccgtggacacggcccaaaaccaggtctccctgactttgaactctgtgaccgccgcagacgccgctgtctatttctgtgcgagaacttatacttatagaaatgcttttgacgtctggggccaggggacattggtcgctgtgtcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgaggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17459 JY8QFUQ01DSJUE unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 645 83.15 153/184 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD4-11*01 ORF 3 X 8 X X.8.X [X.15.38.11] DSRNPRV# out-of-frame - Low V-REGION identity (83,15% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggggtccgccaggctccagggaaggggctggagtgggtctcagggctttgtggaagtgctcctaccacacactacgcagactccgtgaagggccggttcagcatctccagagacctctccaagaatgttctgtttctgcaaacgagcagcctgagagccgaggacacgaccgttttttctgactccagaaatcccagggtaggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17460 JY8QFUQ01DHTRO unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARVRGYYGGQYFDSW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggGaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggcccaggggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcgcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +17461 JY8QFUQ01DIPXM productive Homsap IGHV1-69*04 F, or Homsap IGHV1-69*09 F or Homsap IGHV1-69*11 F (see comment) 660 78.97 169/214 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [0.17.38.11] CAKERDYGSGTYNWFDPW in-frame + Low V-REGION identity (78,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgggggcgtcttcaattattatgctattaattgggtgcgacaggcccctggacaagggcttgagtggatgggaaggatcagacctattcaaaatctggtaaactacgcacagacttttgagggcagagtcaccctcaccgcggacgagtctacgaacacagtgtacatggaactgaccaggttgacttccgcggacacggccttttactactgtgcgaaagagagagactacgggtcggggacttataactggttcgacccctggggccagggaacccgcgtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17462 JY8QFUQ01DPP8C productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 911 90.5 200/221 nt 90.05 199/221 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD1-14*01 ORF 3 10 7 13 10.7.13 [1.17.38.11] CARHLQYNRHGFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtagtcattactactggggctggatccgccagaccccaggaaAaggggctggagtggcttgggacaatctattatagcggaagcgcctacatcaacccgtccctcaagagtcgagtcaccatttccgttgacatatctaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattactgtgcgagacacctgcaatataatcgacatggttttgatttctggggccaggggacaacggtcaccgtctcttcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17463 JY8QFUQ01B5K0B productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggattcagcttcagtacctataacatgaactGgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttctccctggcaccctcctccaagagcacctctggggggcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17464 JY8QFUQ01DRXQO productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 988 96.24 205/213 nt 95.77 204/213 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.16.38.11] CAREDGSGRRHFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ctctggtggctccatcagtagttactactggagctggatccggctgccccaggaaagggactggagtggattgggtatatcttttacactgggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17465 JY8QFUQ01BW3P7 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17466 JY8QFUQ01CP3MY productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 850 88.43 191/216 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 7 14 8.7.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ggttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17467 JY8QFUQ01DMOXB productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 755 83.72 180/215 nt 82.79 178/215 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 7 18 8.7.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DMOXB ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 93 of V-REGION: 'A' (1 nucleotides at position 181 to 181 in the user submitted sequence), (cause frameshift); cctctggattcagtttcactggttttaccgtgatctgggtccgccaggctccaaggaaggGggctggaatggatctcatccgtcactactaatggtctcacgtactacgcagactcagtagagggccgattcaacatctccagggacaacgccaacaatttagtgtttctgcaaatgaacAaccctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggctccagggcttcttcccccag +17468 JY8QFUQ01A9R46 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 982 94.52 207/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [2.17.38.11] CAKDFTYAFDLW in-frame - gcgtctggattcacgttcagtagttatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatcatctggtatgatggaagtaatcaatattatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacggtgtatctacaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgaaagattttacgtacgcctttgatctctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctccgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17469 JY8QFUQ01BTW3T No results +17470 JY8QFUQ01DORH9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca +17471 JY8QFUQ01CP1JK productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtccaaggactacttccccgcaaccggtgacggtgtcgtggaaact +17472 JY8QFUQ01A3HFQ unknown (see comment) Homsap IGHV3-48*01 F 1090 100.0 219/219 nt 8 8 X 8.8.X [2.17.38.X] null + No rearrangement found gcctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17473 JY8QFUQ01CO93B unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 418 96.63 86/89 nt 8 3 X 8.3.X [1.17.X.X] null - No rearrangement found ctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagta +17474 JY8QFUQ01CJP3R productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt 87.1 189/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.16.38.11] CVRDSGPSGYARYESMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) cctctggattcagcctcacttcctatggcatgaactgggtccgccagctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17475 JY8QFUQ01A0BNB unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 X 8.7.X [4.17.38.11] CARGGPHFMI (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggcccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17476 JY8QFUQ01AJ8VO unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [0.17.38.11] CARDRRGYSYEMDY## out-of-frame - in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataGccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17477 JY8QFUQ01CSRVY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + tctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +17478 JY8QFUQ01BT86E productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 784 84.47 185/219 nt 83.56 183/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); tgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17479 JY8QFUQ01APUS4 productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame - cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17480 JY8QFUQ01B73FI productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 738 82.49 179/217 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17481 JY8QFUQ01CRWPM unknown (see comment) Homsap IGHV3-74*03 F 113 54.33 69/127 nt 8 8 X 8.8.X [1.17.7.X] null - No rearrangement found cctctggattcaccttcagtagctactggatgcactgggtccgccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17482 JY8QFUQ01BCUIL productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17483 JY8QFUQ01A98PF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17484 JY8QFUQ01ASBBA productive Homsap IGHV3-11*01 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - gcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17485 JY8QFUQ01CHTSN productive (see comment) Homsap IGHV3-7*02 F 900 90.78 197/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 146 to 146 in the user submitted sequence), (cause frameshift); ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatgggaCgtgaggcatactatgTcggactctgtgaagggccgattcaccatctccaCgagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17486 JY8QFUQ01C9U1A unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 874 89.04 195/219 nt 88.58 194/219 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [2.17.38.11] CAREGGRGYDMDV## out-of-frame - in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtatctatgccatgacctgggtccgccaggctccagggaaggggctggagtggatttcatttatcactgataGggggtagtacccaatactacgcagactctgtgaagggccgattcaccgtctccagggaccaagccaagaactcactgtatctacaaatgaacaacctgggagtcgaggacacggctgtgtattattgtgcgagagaggggggacgtggctacgatatggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17487 JY8QFUQ01BXMPA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17488 JY8QFUQ01BWEN5 productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-13*01 F 1 10 7 18 10.7.18 [1.17.38.11] CARDRYVVDSSWYGNFFDPW in-frame + tctctggtggctccatcagcagtggtacttactactggagctggatccggcagcccgccgggaaggcactggaatggattggacatatctctaccagtgggagtaccacctacaacccctccctcaagagtcgagtcaccatatcagctgacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcagacacggccgtgtattattgtgcgagagatcgatatgtcgtggacagtagctggtacggcaactttttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +17489 JY8QFUQ01ANBVT No results +17490 JY8QFUQ01ATJJ5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17491 JY8QFUQ01DXAFD unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGGGGMTIPLDK## out-of-frame + ctctggattcacctttagcaactatgccatgagttgggtccgccaggctccaggcaaggggctggaatggttggctgctatatggtatgatggaagtaataagtattatgcagactccgtgaggggccgattcaccatttccagagacaattccaagaacactctgtatctgcaaatgaatgacttgagagacgaagatacggctttttattcttgtgcgagaggcggcggtggtatgaccattccacttgacaaatggggccgggggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +17492 JY8QFUQ01C1E74 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +17493 JY8QFUQ01CZ478 productive (see comment) Homsap IGHV1-2*02 F 812 86.85 185/213 nt 86.38 184/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.16.38.11] CARCLWISGTYHFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) tggatatactttcaccgaccattatgtttactggatgcgacaggccctgganaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17494 JY8QFUQ01AMSPA unknown (see comment) Homsap IGHV3-21*04 F (see comment) 667 78.54 172/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (78,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctccggtttcatcttcagtcacttcagcatgaactgggtccgccaggctccaggaaagggcctggagtggatcgccgacatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcgacgatacggccacctattattgtgtgaggctcttcaccagcgatggagtgagaggcgactactgggggccagggcgcccgggttctcgtctccgcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17495 JY8QFUQ01AHIDS productive (see comment) Homsap IGHV3-48*01 F 1008 96.31 209/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDQSPGVAVAGPDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 157 to 157 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagatatagtatgaactgggtccgccaggctccaggaaaAGggggctggagtgggttgcatacattagaagtagcagtagtgtcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccAaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcaaagtccgggtgtagcagtggctggtcctgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17496 JY8QFUQ01CA9EZ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 974 93.67 207/221 nt 93.21 206/221 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD5-18*01 F 3 10 7 14 10.7.14 [1.17.38.11] CARSQSRYSWGDFLHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagcagtactagttactactggggctggatccgccagcccccagggagggggctggagtggattggaagcatctattatagtgggagcacctcctacaacccgtccctcaagagtcgaatcaccatgtccatagacatgtccAaagaaccaattctccctgaggctgagctctgtgaccgccgcagacacggctgtttatttctgtgcgcggtcccagagtagatacagttggggtgacttcttacactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +17497 JY8QFUQ01CROTA No results +17498 JY8QFUQ01C6QGX productive (see comment) Homsap IGHV3-48*01 F (see comment) 764 84.19 181/215 nt 83.26 179/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaAaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +17499 JY8QFUQ01ADUEL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17500 JY8QFUQ01AXW72 productive (see comment) Homsap IGHV4-61*02 F (see comment) 753 82.73 182/220 nt 82.27 181/220 nt Homsap IGHJ4*02 F (see comment) 96 66.67 32/48 nt Homsap IGHD3-16*01 F 3 9 7 16 9.7.16 [1.17.38.11] CARERGASIGEAGGLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) tctctggtggcccgtcaacaatggtgatcagtattggagctggatccggcagcccgccgggaaggggctggagtggatcggacgtgtttctgctagtgggacctacagctacaatccctccctcaggagtcggatcaccatctcaatagacatgtctaagaatcacttctccctgaggttgatttctgtgacggccgcagacacggccttatattattgtgcgagagagcgtggtgcgtcgattggcgaagcgggaggccttgactcctggggccagggaaccctggtcacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +17501 JY8QFUQ01A2H3P No results +17502 JY8QFUQ01CPGSM productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +17503 JY8QFUQ01CBBZ2 unproductive Homsap IGHV4-61*02 F 902 90.05 199/221 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD1-1*01 F 1 10 7 X 10.7.X [1.17.38.11] CAREKVVIRPNWFD#PW out-of-frame + tctctggtgactccatcaccagtggtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaatccctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagagaaaaagtagtgatccgtcccaactggttcgaccccctggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17504 JY8QFUQ01A26DA productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F (see comment) 768 82.96 185/223 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 10 13 8.10.13 [1.17.38.11] CSTGGPNGYHSTYPW in-frame + Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcgccttcaatatcaagtggatgagttgggtccgccaggctccggggaaggggcttgagtgggtcggccgcatcaagagcagcgctgatggtgcgacaacagacaccattgagcgcgtgagagacagattcaccatctcaagagatgactcaaaaaatacactgtacttgcacatgaccagcctgagaaccgaggacacaggcatgtattattgttccacaggcgggccaaatggatatcactccacatatccctggggcccggggacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17505 JY8QFUQ01BF5VH unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 891 90.32 196/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGEFYYETSGRRG#FDYW out-of-frame + stop codons in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'A' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); ctctggattcaccttcactacctcctggatgcactgggtccgccaagctccagggaaGggggctaatgtgggtcgcacgtattaataAgggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaccacactgtacttggaaatggacagtctgagagtcgaggacacggctatgtattattgtgcaagaggggaattttactatgaaactagtggtcgaagggggttttgactactggggccagggaaccctggtcatccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17506 JY8QFUQ01AGAPD productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt 94.06 206/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [2.17.38.11] CVRRGMVAGRYDAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtagttataGgcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17507 JY8QFUQ01C5CQD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F, or Homsap IGHJ5*02 F 73 61.7 29/47 nt Homsap IGHD5-18*01 F 3 8 8 5 8.8.5 [1.17.38.11] CASYGQW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggcagggacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc +17508 JY8QFUQ01BJ7YX unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt 88.37 190/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDPRDYCSGGYCL#GAFDIW out-of-frame - in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 135 to 135 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccCttatcactagacacgtccaagaaccagttctcCcctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgtttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17509 JY8QFUQ01AH2WS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CANEVGYCSGRG in-frame - ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtcgggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17510 JY8QFUQ01C5UQJ No results +17511 JY8QFUQ01CE7G4 productive (see comment) Homsap IGHV3-23*05 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagactgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +17512 JY8QFUQ01A0S1H productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATDDSNGWDEVADYW in-frame + ctctggattcaccttcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +17513 JY8QFUQ01DKQ2M unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 984 93.72 209/223 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD2-15*01 F 3 8 10 X 8.10.X [1.17.38.11] CAADGCPGGTCYHGFDM## out-of-frame - ctctggattcactttcagtaacgtctggatgcactgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgctggtggggcaacagaatacgctgcgcccgtgagaggcatattctccatctcaagagatgattcaaagaacacgttgtatctgcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtgccgcagatggttgtcctggtggtacctgctatcatggttttgatatgtgggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17514 JY8QFUQ01B5EZ8 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 917 90.18 202/224 nt 88.84 199/224 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD6-6*01 F 1 8 10 X 8.10.X [1.17.38.11] CTSNSWLDR## out-of-frame + in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'GC' (2 nucleotides at position 79 to 80 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'AG' (2 nucleotides at position 92 to 93 in the user submitted sequence), (cause frameshift); cctctggattctctttcagtaatgcctggatgaattgggtccgccaggctccagggGAagggggctggaatgggttggGCccatattaaaaAGgggaaattgatggtgggataacaaactacgctgcacccgtgaagggcagattctccatcgcaagagatgattcaaagaatatgatgtatttgcaaatgaacagcctgaacaccgaggacacaggcgtgtattactgtacctcaaattcgtggctcgaccgctggggccagggaaccccccgtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17515 JY8QFUQ01ALDNB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); gcctccggattcacctttagtagtttctggatgcactgggtccgccaagttccagGgggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgctggtccagggcttcttccccca +17516 JY8QFUQ01CXJ4R productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17517 JY8QFUQ01AWBYK unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 747 82.49 179/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17518 JY8QFUQ01CLNA3 No results +17519 JY8QFUQ01BS0MI productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctctggattcgccttcagttggtattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgntgagcctctgcagcacccagccagatgggaacgtgtcatcgcctgcctggtccagggcttcttcccc +17520 JY8QFUQ01DKRI1 productive Homsap IGHV3-21*04 F 955 93.15 204/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17521 JY8QFUQ01CKLRC productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 81 to 86 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17522 JY8QFUQ01C4FP2 No results +17523 JY8QFUQ01CYOQ9 productive Homsap IGHV3-72*01 F 1088 98.66 221/224 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 163 76.79 43/56 nt Homsap IGHD6-13*01 F 3 8 10 10 8.10.10 [1.17.38.11] CARAVSHQVDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtgcgagagccgtgtcgcatcaggtggacgtctggggccaaggggccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcnacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17524 JY8QFUQ01CMHJ0 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 823 87.04 188/216 nt 85.65 185/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); gtctctggggactccattagtggttactattggacgtggatccggcagAgccccagggaagggactggagtggattggaaatgtccattacacCtgggagtaCccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17525 JY8QFUQ01AKTN5 No results +17526 JY8QFUQ01BEQKB productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccccatggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +17527 JY8QFUQ01C0WDO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17528 JY8QFUQ01C7DRB productive Homsap IGHV4-4*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcgccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17529 JY8QFUQ01B8I95 No results +17530 JY8QFUQ01BCJ3M unproductive Homsap IGHV3-48*03 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDRADLFYDSSGYQFDL## out-of-frame + ctctggattcatcttcagcgatcatggaataaactgggtccgccaggctccggggaagggtctggagtggatttcattcgtcagtagtaggggtgggaccatccactacgcagactctgtgaagggccgattcatcatctccagagacaactccaggaacacagtatttctacaactgaacagactgagagacgaagacacggctatttattattgtgcgagagacagggcggatttgttctatgatagcagtggttaccaatttgatctttggggcccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17531 JY8QFUQ01BAG1V productive Homsap IGHV1-3*01 F 822 87.38 187/214 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [0.17.38.11] CVRGRSPPGDWFDPW in-frame + tggatacaccttcactaattatgctctgcaatgggtgcgccgggcccccggacaaacttttgagtggctgggatggatcaactctgccaatggcaacacaaaatattctcagaagtttcagggcagagtcgccattaccagggacacatccgcgaggacaacttacatggaattgagcagtctgacatctgaagacacggcgacatattattgtgtgagaggaagaagtccgcccggcgactggttcgacccctggggccagggaaccctggtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17532 JY8QFUQ01CBLPY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 155 to 155 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccGagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17533 JY8QFUQ01BPLZQ unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 101 53.08 69/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons tctggattcaccttcagtaactatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +17534 JY8QFUQ01BFZ6J productive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17535 JY8QFUQ01B0ZM2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17536 JY8QFUQ01CJWXE No results +17537 JY8QFUQ01BNS5M productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 962 92.41 207/224 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.38.11] CTHLREEMSYEW in-frame + cctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +17538 JY8QFUQ01AHMBY unproductive Homsap IGHV4-4*01 F, or Homsap IGHV4-4*02 F or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 779 84.4 184/218 nt 83.94 183/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD1-26*01 F 1 9 7 X 9.7.X [1.17.38.11] CARSFESYHPNVALDI## out-of-frame - Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); ctccggaggcctccatcagcactattcattggtggaattgggtccgccagTcccccgggaaaggggctggagtggattggagaagtctatcatagtgggaacaccaactataacccgttcctcaagagtcgagtctccattgcagtcgacaaggccaagaaccaggtctccctgactgtgacgtctgtgaccgccgcggacacggccacatatttctgtgcgagaagttttgagagctaccatccaaatgtcgctttagacatctgggggccaagggacaagggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17539 JY8QFUQ01C5XWP No results +17540 JY8QFUQ01A1BXP unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 927 92.17 200/217 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctactggatgcaactgggtccgcaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagctcgacagcacccccccaagatgggaacntggtcgtcgcatgcctggtccagggcttcttccccc +17541 JY8QFUQ01C1MKT productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*07 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-14*01 ORF 3 8 8 12 8.8.12 [1.17.38.11] CARVHRNSMNFDYW in-frame + ctctggattcgccttcagtagctatgctatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcatatgatggaagtaatgaatactacgcagactccgtgaagggccgattcaccatttccagagacatttccaacaacacgctgtatctgcaaatgaacagcctgagagcggaagacacggctgtgtattactgtgcgagagtccaccgtaacagcatgaattttgactactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaa +17542 JY8QFUQ01AJTUX productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 630 93.1 135/145 nt 92.41 134/145 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 7 16 8.7.16 [1.17.14.11] CARGPVGISESVNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 65 of V-REGION: 73 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagaggtccggttgggataagtgaaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17543 JY8QFUQ01AFVUY productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARFSGSYKSAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); ggttctggatacatctttaccgactattggatcggctgggtgcgccagacggccgggaAaaggcctggagtggatgggaatcatctatcctggtgactctgacaccagttatggcccgtccttccaaggccaggtcaccatttcagccgaccagtccatcaccaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagattcagtgggagttacaaatcggcttttgatatctggggccgagggacaatggtctccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17544 JY8QFUQ01CCBVJ unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 435 76.67 115/150 nt 8 7 X 8.7.X [1.17.16.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CCBVJ ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (76,67% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactacttccccgaaccggtgacggtgtcgtggaactcag +17545 JY8QFUQ01C7QF9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17546 JY8QFUQ01CIV0V productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 964 93.61 205/219 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [2.17.38.11] CAREVSDALDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcatctttgatgattttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17547 JY8QFUQ01DQKT0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSGPSGYARYESMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17548 JY8QFUQ01A8UPT No results +17549 JY8QFUQ01DJBIE productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARRDVGSHAFDLW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ttctggatacaattttaactacgactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatggtctatgttgGgtgactctgatgctagatacagcccgtcctccgaaggccaggtcaccatctcagccgacaaggccatcagtaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggatgtgggttcacatgctttcgatctgtggggccaagggacaatggtcaccgtttcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +17550 JY8QFUQ01C0X2L No results +17551 JY8QFUQ01CPAEA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 661 78.24 169/216 nt 77.78 168/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (78,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaGgggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17552 JY8QFUQ01DUZ2M unknown (see comment) Homsap IGHV1-2*02 F 512 87.22 116/133 nt 8 8 X 8.8.X [0.17.11.X] null + No rearrangement found tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatgcatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaacc +17553 JY8QFUQ01CNQBQ No results +17554 JY8QFUQ01BW8SZ productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17555 JY8QFUQ01ANU9C productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 2 8 8 9 8.8.9 [1.17.38.11] CARDNYGDYWG in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17556 JY8QFUQ01AQT5K productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17557 JY8QFUQ01AXWVT No results +17558 JY8QFUQ01B7UKL productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17559 JY8QFUQ01DSTHX productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17560 JY8QFUQ01CF57Z productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 858 89.25 191/214 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17561 JY8QFUQ01AFFU5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17562 JY8QFUQ01AJWRX unproductive (see comment) Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKEEF*HWLDTTG##W out-of-frame + stop codons cctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaattttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgaccagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17563 JY8QFUQ01CYV58 productive (see comment) Homsap IGHV1-2*02 F 939 93.46 200/214 nt 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 83 to 88 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacgGggcccctggacAaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17564 JY8QFUQ01BT3X8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1090 95.78 227/237 nt 95.36 226/237 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 166 74.19 46/62 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [8.17.38.11] CAKGRGYSRDLVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift); ctgagactctcctgtgcagcctctggattcacAttttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaggtgtcagtggtagtggtgataagacatactacgcagacttcgtgaagggccggttcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagggaggggttatagcagagacttggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgttgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17565 JY8QFUQ01AEL64 unproductive (see comment) Homsap IGHV3-72*01 F 944 91.52 205/224 nt 90.18 202/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame - stop codons in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'GC' (2 nucleotides at position 30 to 31 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); cctctggattcaccttGaagtgatcactaGCatgggactgggtccgccaggctccaAgggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17566 JY8QFUQ01AEGV0 productive Homsap IGHV3-74*03 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + cctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17567 JY8QFUQ01CGT9A productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVRGRIVSVGMAGWFDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 177 to 177 in the user submitted sequence), (cause frameshift); tctctggattcaccttcaggaactattggatgcactgggtccgccaagctccagggaaggggctggagtgggtctcacgtatcaatggcgacggaagtagcacaagctacgcggactccgtgaagggccgattcaccatctccagagacaacgccgagaacacgctgtatctgcaaAatgaacagtctgagagccgaggacacagccgtatatttttgtgtaagaggccgtatagtgtcagttggtatggcaggctggttcgacccctggggccagggaacgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17568 JY8QFUQ01B4SR5 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 797 85.32 186/218 nt 84.4 184/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CVKDYGNCAGGRCYSIP##DYW out-of-frame + stop codons in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'GTTT' (4 nucleotides at position 99 to 102 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccgggAaaaggggctggagtgggtctcaggcatcactgatggtggtggGTTTtttgacatactacgcagacgccgtgcagggccggtttattatttccagagacgattcccagaacacgatagatctgcaaatgaacaatttgagagccgacgacacggccatctattactgtgtgaaagattacggcaattgtgctggtggtcgctgctactcgattccccgttgactattggggccggggaaccgtggtcaccgtctcctcagcatccccgaccagcccccaaagggtcttcccgctgagcctcgacaacacccccctaagatgggaacgtggtcgtcgcatgcctggtccaggcttctcccca +17569 JY8QFUQ01BBVME productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17570 JY8QFUQ01DSXV6 productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 876 90.19 193/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [0.17.38.11] CATDRCTGGTCCPHYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'AC' (2 nucleotides at position 45 to 46 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AC' (2 nucleotides at position 84 to 85 in the user submitted sequence), (cause frameshift); tggatacactttcaccagttattatatacactgggtgcgacaggACcccctggacaggggcttgagtggatgggagttgtcaaACccctggtgctgaatacacactctacgcacagaagttccagggcagactcaccttgaccagggacacgtccacgagcacagtctacatggagttgagtagcctgagatctgaggacacggccctgtattactgtgcgacagataggtgtactggtggtacctgctgtccacattactggggccagggaaccctgatcaccgtctcctcagcctccaccaagggcccatcggtcttaccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17571 JY8QFUQ01CY1GJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17572 JY8QFUQ01DXEI5 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattgGgggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17573 JY8QFUQ01C4CFG productive (see comment) Homsap IGHV3-48*01 F 797 85.32 186/218 nt 84.86 185/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); gctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggcgctggagtggAttttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17574 JY8QFUQ01B2RHD unproductive Homsap IGHV3-48*02 F 894 91.12 195/214 nt 90.65 194/214 nt Homsap IGHJ6*01 F 104 65.45 36/55 nt Homsap IGHD3-22*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDHNWAYDY# out-of-frame + in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcagtttcagtagctacaatgtaaattggatccgccaggctccagggaaggggctggagtggatttcatacattagtactactaatgccatatactacgcaaactctgtgaggggccgattcaccatctccagagacaatgccatgaactcattgtatttgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagatcacaattgggcatatgactactggggccagggaaccctgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +17575 JY8QFUQ01ACD88 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 929 91.4 202/221 nt 90.05 199/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [2.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'GT' (2 nucleotides at position 80 to 81 in the user submitted sequence), (cause frameshift); gccctcctggattGcaccttGcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtcGTacccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctcccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17576 JY8QFUQ01BLTS4 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 823 86.64 188/217 nt 85.71 186/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 56 to 57 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'T' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); tcaggattgcaccttcagtaggtactggatgcactgggtccgccaagttccagggGAagggggccggtntgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaaTgggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +17577 JY8QFUQ01C1WLX productive (see comment) Homsap IGHV1-8*01 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ1*01 F 188 84.62 44/52 nt Homsap IGHD4-23*01 ORF 2 8 8 13 8.8.13 [0.17.38.11] CARGSLDYGGLPQHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagttatgatatcaactgggtgcgacaggccgctggacaagggcttgagtggaAtgggatgggtgaaccctaatagtggtgccacaggctatgcacagaagttccagggcagagtcaccatgagcagggacacctccgaaagtacagcctacgtggagctgagcagcctgggatctgaggacacggccgtgtatttctgtgcgagaggctccctggactacggtggcctcccccagcactggggccagggcaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17578 JY8QFUQ01CXOYT unknown (see comment) Homsap IGHV1-NL1*01 P 90 56.79 46/81 nt 2 X X 2.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagagac +17579 JY8QFUQ01CF4SX productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [2.17.38.11] CARLPNTIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); gcgttctggatatagttttgGccacctactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatCgggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatttcagccgacaagtccctcagtatcgcctacctgcagtggagcagcctgcaggcctcggacaccgccatatattactgtgcgagactgcctaacactattgactcctggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17580 JY8QFUQ01CE7H7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17581 JY8QFUQ01B7YG7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17582 JY8QFUQ01CJN3R No results +17583 JY8QFUQ01CQCUX productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1025 95.54 214/224 nt 95.09 213/224 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-11*01 ORF 3 8 10 18 8.10.18 [1.17.38.11] CARHEGTPVSDVGGYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtggctctgctatgcactgggtccgccaggcttccgggaAaagggctggaatgggttggccgtattagaagcagagctcacagttccgcgacagcatatgcagcgtcggtgaaaggcaggttcaccatttccagagatgattcaaagaacacggtgtatctgcaaatgaacagtttgaaaaccgaggacacggccgtgtattactgtgctagacatgaagggactccagtaagtgatgtaggtggatacggcatggacgtctggggccaagggtccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17584 JY8QFUQ01ACXAI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame + ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17585 JY8QFUQ01CATB8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 769 84.26 182/216 nt 83.8 181/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.16.38.11] CAKDTITMGGDVAPLFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) tctgggattcacctttagtaactatgacatgggctgggtccgccagctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17586 JY8QFUQ01BEMMN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17587 JY8QFUQ01AIBEO No results +17588 JY8QFUQ01BVAYX productive (see comment) Homsap IGHV4-61*01 F (see comment) 776 83.71 185/221 nt 82.81 183/221 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'C' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagTccccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccCatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtccaaggactacttccccgaaccggtgacggtgtcgtggaactc +17589 JY8QFUQ01C80D8 No results +17590 JY8QFUQ01B9KSC No results +17591 JY8QFUQ01DRCW3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 917 92.09 198/215 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARDLRARLWHPMDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaatagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17592 JY8QFUQ01CX6IA productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 804 86.45 185/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CGTSSRAWGADAFDIW in-frame + ctctgggctcagcgtcagtaactaccgcatgggctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagagatgatagtacagatcatgtagattccgtgaagggccgattcaccgtttcccgagacaattccaagaacacattgtaccttcagatgaacagtgtgacagccgaggacacggccgtttattattgtggaactagttcccgcgcctggggcgctgatgcctttgatatctggggccaggggacactggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17593 JY8QFUQ01DOVD6 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 103 62.9 39/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17594 JY8QFUQ01BK9D5 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.37.11] CAKNNNDFGDYDWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactgggggcaccgactccaaccctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcacctgcctggtccagggcttcttccccca +17595 JY8QFUQ01BWD62 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 872 89.77 193/215 nt 88.84 191/215 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'GA' (2 nucleotides at position 79 to 80 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); tatatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggGAaaatcaatcacagtggaaCgccccaactacagcccgtccctcaatagtcgagtcatcatatcgatagacacgtccaagaaccaggtctccctgaagctcttctctgtgaccgccgcggacacgggtgtgtactattgtgcgaggcccacgtatagtagcggccgggacgcctttgatacctggggccaagggacgacggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +17596 JY8QFUQ01ABNP9 productive Homsap IGHV3-74*03 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame - ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17597 JY8QFUQ01AOZ1H productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17598 JY8QFUQ01BGBRB unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 641 85.14 149/175 nt 84.57 148/175 nt 8 8 X 8.8.X [0.17.25.X] null + No rearrangement found in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccaggcactatatgcactgggtgcgacaggCcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggggcagagtcgccgtgaccagagacacgtccacgagcacagggcttcttccccca +17599 JY8QFUQ01BU594 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 799 84.68 188/222 nt 81.53 181/222 nt Homsap IGHJ3*01 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-16*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARTYTYRNAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,68% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 34 of V-REGION: 'ACC' (3 nucleotides at position 22 to 24 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'AG' (2 nucleotides at position 41 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'GG' (2 nucleotides at position 112 to 113 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 130 to 130 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'GG' (2 nucleotides at position 166 to 167 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 184 to 184 in the user submitted sequence), (cause frameshift); tcctttggtgactctctgagtACCagtagcagtttctactAGggggctgggtccgccagGaccccagggaagggactggagtgggttgggactgtttattatagtgggagcGGccccactacaatccgtCccctcaagagtcgagtcgccatatccgtggacacgGGccccaaaaccaggtctCccctgactttgaactctgtgaccgccgcagacgccgctgtctatttctgtgcgagaacttatacttatagaaatgcttttgacgtctggggccaggggacattggtcgctgtgtcttcagcatccccgaccagccccaaggtcttccccgctgagcctctgcagcaccccagccagatgagggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17600 JY8QFUQ01B22B8 unknown (see comment) Homsap IGHV4-31*06 F, or Homsap IGHV4-61*01 F or Homsap IGHV4-61*03 F or Homsap IGHV4-61*04 F 139 58.88 63/107 nt 10 7 X 10.7.X [1.17.X.X] null - No rearrangement found tctctggtgcctccgtcagcagtggtagtttctactggacctggattcgtcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggcttcttccca +17601 JY8QFUQ01AL1BT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctctagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17602 JY8QFUQ01C8VWW productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD5-18*01 F 3 10 7 17 10.7.17 [1.17.38.11] CAGEQMIDAVSHNYAMDVW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01C8VWW ; 8 AA in Homsap_IGHV4-59*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 195 to 195 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcatcaatacttacttctggagttggatccggcagcccccagggaagggactggagtggattgggtatatctctcacagtgggagtgccaactacaacccctccctcgagagtcgagtcaccatcttaagagacacgtccaagaaccagttctctctgaggctgagggctgtaaccCgcggcggacacggccgtgtatttctgtgcgggggaacagatgattgacgcagtctcccacaactatgccatggacgtctggggccaagggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +17603 JY8QFUQ01BN0XS productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17604 JY8QFUQ01AY4XZ productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 678 79.91 171/214 nt 79.44 170/214 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) ctctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17605 JY8QFUQ01CK6XO productive (see comment) Homsap IGHV3-66*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgGggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17606 JY8QFUQ01AGSLZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacatggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17607 JY8QFUQ01DF9CL productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame - ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17608 JY8QFUQ01B9WA9 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt 85.78 187/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDDGGHMTLDVW# out-of-frame + in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGgggcacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctgggggcccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggcccctgggctncctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17609 JY8QFUQ01ASM68 productive (see comment) Homsap IGHV3-7*01 F 922 92.13 199/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 8 14 7.8.14 [1.16.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 78 in the user submitted sequence), (cause frameshift) cctctggatttacttttacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17610 JY8QFUQ01B2Q5F productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct +17611 JY8QFUQ01CHDJL productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +17612 JY8QFUQ01AMLKN productive Homsap IGHV3-30*08 F, or Homsap IGHV3-30*16 F 923 91.74 200/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGKAGHTHYGLDVW in-frame + cctctgcattcaccttcagtagttatgctatgcactgggtccgccaggccccaggcaaggggctagagtgggtggcagttatatcaaatgatggaaattataacgactatgcagactccgtgaaggggcgattcaccatttccagagacaactccaagaacacgctatttctacaaatgaatagcctgagagttgaggacacggctgtctataactgtgcgagaggaaaggctggccatacccactacggattggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17613 JY8QFUQ01AGHU9 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt +17614 JY8QFUQ01BBOR9 productive Homsap IGHV3-21*04 F 990 95.39 207/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame + ctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17615 JY8QFUQ01COWTP unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGG# out-of-frame + ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggaccagggagcctggtctccgtctcctcagcatccccgaccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtccatcgcctgcctggtccagggcttcttcccc +17616 JY8QFUQ01ACVT5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtccgtcgcatgcctggtccagggcttccttcccccgag +17617 JY8QFUQ01C7QDR No results +17618 JY8QFUQ01AYI9R productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*07 F (see comment) 738 82.49 179/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-13*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAREADGQDLTTHLNWFDPW in-frame - Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcatcttcagtgcctacgctatgcactgggtccgcctgtctccaggcaggggcctagagtgggtggcaggaatctcacacgatggcagtcagacagactacgcagcctccgtgaagggccggttcatcatttctagagacaattccaaagacacagtgtttctggaaatgaaaagcctgggcggagaagacacggctgtttactattgtgcgagagaagcagatgggcaagacctgacgacccacttgaactggttcgacccctggggccagggaatccaggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17619 JY8QFUQ01BGAZN productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 843 87.27 192/220 nt 86.82 191/220 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); cctccgggagttcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatGagtatggggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17620 JY8QFUQ01CYLN8 No results +17621 JY8QFUQ01AK8CV unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ2*01 F (see comment) 94 64.15 34/53 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDYW# out-of-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataGccttagtagtggtagtgataccatatactacgcagactctgtgaGggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacaggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +17622 JY8QFUQ01BWSIV No results +17623 JY8QFUQ01B231X productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 81 to 86 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17624 JY8QFUQ01AGYY9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17625 JY8QFUQ01CRBLN productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17626 JY8QFUQ01BE2KX unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactanttccccgaaccggtgacggtgtcgtggaactc +17627 JY8QFUQ01CXQX3 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARKESPRGDFLW#DYW out-of-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +17628 JY8QFUQ01BM9DJ productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 894 91.12 195/214 nt 90.65 194/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-18*01 F 1 8 8 15 8.8.15 [0.17.38.11] CAIVDTNLVSATGKDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'AC' (2 nucleotides at position 45 to 46 in the user submitted sequence), (cause frameshift); tggatacaccttcagcaactactatagacactgggtgcgacaggACcccctggacaagggcttgagtggatgggaatgatcaaccctagtagtgattacaaatattacgcacagaaatttcagggcagagtcaccatgaccagggacacgtccacgagcacagtcttcatggagctgagtagcctgagatctgacgacacggccgtgtattattgtgcaatagtggacacaaatttggtttcggcgaccggtaaagactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17629 JY8QFUQ01C1YPN unproductive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 933 91.82 202/220 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD6-19*01 F 2 10 7 X 10.7.X [1.17.38.11] CAAYDSGWYKH## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggtggctccgtcaacagtggtgattactactggacctggatccgccagcaccctgggaagggcctggagtggattggatacatctattacagtgggagcacttactacaatccgtccctggagagtcgagttaccatatcaatagacatgtttaagaaccagttctccctgaaagtgagctctgtgactgccgcggatacggccgtgtatcattgtgcggcgtatgacagtggctggtacaaacactgggggccagggaaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17630 JY8QFUQ01ALZ5E No results +17631 JY8QFUQ01BN3NW unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ2*01 F (see comment) 94 64.15 34/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 144 to 144 in the user submitted sequence), (cause frameshift); cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccCagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggcccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17632 JY8QFUQ01BZS1D productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1033 96.4 214/222 nt 94.14 209/222 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 10 17 8.10.17 [1.17.37.11] CTRDNPPLRSLEWLPFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 90 of V-REGION: 'G' (1 nucleotides at position 181 to 181 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'CA' (2 nucleotides at position 196 to 197 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 80 of V-REGION: 1 nucleotides (from position 151 in the user submitted sequence), (cause frameshift) ttctggattcacctttggtgattatagtatgagttggttccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcaAaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaaggatgattccaAaaagcatcgcctatctgcGaaatgaatagcctgCAaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17633 JY8QFUQ01AKHUT unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 481 94.39 101/107 nt 8 8 X 8.8.X [1.17.1.X] null + No rearrangement found ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatact +17634 JY8QFUQ01CSM2A productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggGaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17635 JY8QFUQ01BYVM2 productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYHFDYW in-frame + ctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17636 JY8QFUQ01ADLGV productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.16.38.11] CATSRGSANWYPFDHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 86 of V-REGION: 'A' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtgcctctggcataAaactgggtccgccaggctccagggaaggggctggaatgggtctcatcatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaacAtcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17637 JY8QFUQ01BOX0R productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17638 JY8QFUQ01BSSC9 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttacccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17639 JY8QFUQ01DGGVK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ3*02 F (see comment) 142 76.0 38/50 nt Homsap IGHD1-1*01 F 3 8 8 17 8.8.17 [1.17.38.11] CAKDIWAREWNDMAAFQMW in-frame + Other possibilities: Homsap_IGHJ1*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtcgcaagcattagtgccaggggcgacagttcatactacgcagactccgtgaagggccgattcaccatctccagggacaatcccaggaccacattgtatctggaaatgaacagtctgagagtcgaagacacggccacatattattgtgcgaaagatatctgggcgcgagagtggaacgacatggcggcttttcagatgtggggccaggggacacttgtcattgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca +17640 JY8QFUQ01BP5LW productive (see comment) Homsap IGHV3-11*01 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17641 JY8QFUQ01BLU5T unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 90 81.48 22/27 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found ctccgggggacagtgtctctagcagca +17642 JY8QFUQ01AMCQ7 productive (see comment) Homsap IGHV4-34*13 F (see comment) 646 78.4 167/213 nt 77.93 166/213 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [2.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (78,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); tctctgatggggtcgttcatgggttacctctggaattGggatccgccagcccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17643 JY8QFUQ01AJT2G No results +17644 JY8QFUQ01A1TLL unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 102 53.03 70/132 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17645 JY8QFUQ01BX21F unproductive (see comment) Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKEEF*HWLDTTG##W out-of-frame + stop codons cctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaattttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17646 JY8QFUQ01A4HRX unknown (see comment) Homsap IGHV3-23*05 F 99 52.59 71/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons cctctggatacagttttaacagttatgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17647 JY8QFUQ01BUHDG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARDRLTISALDY## out-of-frame + cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17648 JY8QFUQ01DNVXO unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 796 85.65 185/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAGA#LDYW out-of-frame + stop codons tctggattcaccttttccaactgtgacatgagctgggcccgccagattccagggaaggggctggagtgggtctcagttatttctggaggtgattttggaacatctgacgcagactccctgaagggccggttcaccatctccagagacaattccaaggacacgttgtgactgcaaatgaaccgcctgagagccgaggacacggccctatatatgtgtgccggggcccttggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtccgtggaactcagg +17649 JY8QFUQ01CSU3T No results +17650 JY8QFUQ01CEW67 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17651 JY8QFUQ01DFDL8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGMYASGWA#FDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcagttttagtagtcatggcatgagttgggtccgccaggctccagggaaggggctggagtgggtctcaggtgttagtagtgctgatggccggacacactacgcagagtccgtgaagggccgattcatcatctccagagtcaattacgagaataccctgtacctgcaaatgaatgacctgacagccgaggacacggccgtttattattgtgcgaaagggatgtatgccagtggctgggcccctttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17652 JY8QFUQ01B0QYK productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggctcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17653 JY8QFUQ01C1E0F productive (see comment) Homsap IGHV3-7*01 F 960 93.18 205/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); agcctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17654 JY8QFUQ01CGZ5P unproductive Homsap IGHV4-4*07 F 791 85.58 184/215 nt 84.65 182/215 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CAREGLLWFGELWAG#WFDSW out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'GCAGTG' (6 nucleotides at position 19 to 24 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); tctctggaggctccatcaGCAGTGgaagttactactggacctggatccggcagcccgccgggaagactctggagtggaTttgggcgcttctacagtcgtgggggtgtcgactacaacccctccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagagggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17655 JY8QFUQ01A3KRW unproductive Homsap IGHV3-30*06 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD2-8*02 F 3 8 8 X 8.8.X [2.17.38.11] CARDPDSTGSLWFFDH## out-of-frame + gcgtctggattcaccttcactagttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatctcaaatgatggaagaaataaatactacgcagactccgtgaagggccgattcagcatctccagagacaactccaagaacatggtgtatctgcaaatgaacaacctgagagttgaggacaccgctctcttttattgtgcgagagacccagacagtactggttctttatggttctttgaccattggggcccagggaacccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17656 JY8QFUQ01A1B2W productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 929 91.4 202/221 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 1 10 7 19 10.7.19 [1.17.38.11] CARQLEEGREVLQWNDAFAIW in-frame + tctctggtggctccatcaacagtagtagttatcactgggcctggatccgccagcccccagggaagggactggaatggattggcagtatgtcttatagtggggacacctactacaatccgtccctcaagagtcgagtcgccatatccgcagacacgtccaggaaccggttctccctgaagttgagctctctgaccgccgcagacacggctgtatattactgtgcgagacagcttgaggagggacgggaggtactccaatggaatgatgcttttgctatctggggccaggggacagtggtcaacgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17657 JY8QFUQ01B1I9P productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggcGtggagtgggtctgctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17658 JY8QFUQ01BIG2J No results +17659 JY8QFUQ01A078O No results +17660 JY8QFUQ01AT8GZ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*06 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [0.17.38.11] CARGDGYNFGGLDYW in-frame - ctggattcaacttcataggttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactccgtgaggggccgatccatcatttccagagacgattctaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17661 JY8QFUQ01AOXDB No results +17662 JY8QFUQ01CNDKC productive Homsap IGHV3-7*01 F 887 89.45 195/218 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17663 JY8QFUQ01A4E2R productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 924 93.36 197/211 nt 91.94 194/211 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 7 8 13 7.8.13 [X.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 28 in the user submitted sequence), (cause frameshift) gattcacctttggttattGatggcatgactgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17664 JY8QFUQ01BY6TV productive Homsap IGHV3-7*01 F 886 90.28 195/216 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [1.17.38.11] CARVIPGRGNYAFDVW in-frame - tctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17665 JY8QFUQ01B70AV productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 843 89.1 188/211 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [0.17.38.11] CARPTYSSGRDAFDTW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17666 JY8QFUQ01BNRZG productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 698 80.28 175/218 nt 79.82 174/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAKGLRSRLESW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'ATATCT' (6 nucleotides at position 102 to 107 in the user submitted sequence), (do not cause frameshift); cctctggatttagtttcagcggaagttggatgtactgggtccgccagggtccaggtaagggtctggagtggctgtcacgtaataaagttgcaggaactactATATCTacaagttatgcggactccgtgaggggccgattcaccgttaccagagacggcgccaagaataccatctatctgcaaatgaacagtctgacagtcgacgacacggctgtgtattattgtgcgaaaggacttaggagtcgccttgagtcctggggccagggagtcgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17667 JY8QFUQ01ARBIS No results +17668 JY8QFUQ01AMDQK productive (see comment) Homsap IGHV4-4*07 F 782 85.12 183/215 nt 84.65 182/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 7 9 8.7.9 [1.17.38.11] CARDSGDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'CAA' (3 nucleotides at position 84 to 86 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtcCAAaaccagtggggagccccccactacaacccttccctcaagagtcgagtcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccatttttttctgtgcgagagactccggggactttgactactggggcccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17669 JY8QFUQ01BLXF8 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17670 JY8QFUQ01B4SAK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 937 92.24 202/219 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARDQSLGMPEAFDIW in-frame - gcctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17671 JY8QFUQ01BPX3E unproductive Homsap IGHV3-21*04 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.16.38.11] CVKDMVAGQGLLSRFDH## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 2 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) cctctggattcagcttaagttcttatggcatgaactgggtccgccaggctccaggggggggctgagtgggtctcattcattaacagtattagtagttataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactgggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +17672 JY8QFUQ01CKKB5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17673 JY8QFUQ01AQ18D productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 984 93.72 209/223 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 2 8 10 14 8.10.14 [1.17.38.11] CTTDPRYFWGSGFDYW in-frame + ctctggattccctttcagcaacacctacatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaaactgatggtgggacaatagaatacgctgcacccgtgaaaggcagattaaccatatcaagagacgattcaaaaaacacgctgtatctgcatatgagcagcctgaagatcgaggacacagccgtgtattactgtaccaccgatccccgttacttttgggggagcgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct +17674 JY8QFUQ01B52FN No results +17675 JY8QFUQ01BCWT3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + cctttggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca +17676 JY8QFUQ01CYPIH unproductive Homsap IGHV3-7*01 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CATSPSDFDRRWG#YW out-of-frame - in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); gcctctggatttagctttagaaccttttggatgagctgggtccgccaggctccagggagggggctggagtgggtggccaacataaAagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatggggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17677 JY8QFUQ01ANU0J unproductive Homsap IGHV4-61*02 F 884 89.14 197/221 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD5-24*01 ORF 1 10 7 X 10.7.X [1.17.38.11] CARDFWRFLQFSGLL# out-of-frame + tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc +17678 JY8QFUQ01AWOLO productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.37.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 194 in the user submitted sequence), (cause frameshift) ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggcccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17679 JY8QFUQ01BBXBF productive (see comment) Homsap IGHV3-7*03 F 847 87.67 192/219 nt 87.21 191/219 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [2.17.38.11] CTRRGFMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'GC' (2 nucleotides at position 12 to 13 in the user submitted sequence), (cause frameshift); gcctccggattGCaatttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17680 JY8QFUQ01BKDXY unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 410 83.05 98/118 nt 82.2 97/118 nt 8 7 X 8.7.X [1.17.5.X] null + No rearrangement found Low V-REGION identity (83,05% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) tctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgtttctacttacaccatttctacgcagagtctgt +17681 JY8QFUQ01B99ZE productive (see comment) Homsap IGHV4-34*03 F 885 90.61 193/213 nt 90.14 192/213 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 228 94.12 48/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.16.38.11] CVRNYYDFSGYFNWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tgtctggtgggtccttcagtggttactactggagttggatccgccagccccagggaaggggctggagtggattggggaaatcaattatagaggaagtaccaactacaatccgtccctcaaaagtcgagtcaccgtgtcttcagacacgtccaagaatcagttctccctggagttgatctctgtgaccgccgcggacacggccatatattattgtgtgagaaattactatgattttagtggttatttcaattggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17682 JY8QFUQ01ADOTV unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDNYGDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17683 JY8QFUQ01B1ODF unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDPRDYCSGGYCFVGAFDI# out-of-frame + Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaaggGgactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaaggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaaactc +17684 JY8QFUQ01CBOKC productive Homsap IGHV3-7*01 F 851 88.07 192/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRDRPGGWALDYW in-frame - Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) cctctggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17685 JY8QFUQ01BN3MT No results +17686 JY8QFUQ01AJDOZ unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F (see comment) 743 82.57 180/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 88 64.0 32/50 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CATDLVTSTPGVPR*CLCLL## out-of-frame + stop codons Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggaatcacgttcaacagacatggcattcactgggtccgccaggcccctggcaggggcctggagtgggtggctgttatgtcccgagacggaagtagacaatactatagagactccgtgaagggccgtttcgccatctccagggacacttccacgaacactgtgtatctgcaaatgaacagtctgagagttgacgactcggctctatatcgctgtgcgacagacttggtgacctccacaccgggagtccctcgatgatgcttatgccttttgggggccaaaggggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcggcctgcctcggtctagggcttcttccccc +17687 JY8QFUQ01BDK3Q unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRVGAAILRFLEWLSD#NWFDPW out-of-frame + stop codons cgtctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgcaagtactacttccatacattatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagtctgagagccgaggacacggctgtatattactgtgtaagagtgggggccgccatattacgatttctggagtggctatcagactaactggttcgacccctggggccagggaactctggtcaccgttacctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +17688 JY8QFUQ01CVX35 unproductive Homsap IGHV3-9*01 F 922 92.13 199/216 nt 90.74 196/216 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.37.11] CVKRSGNYR#NWFDIW out-of-frame - in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 176 to 176 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'A' (1 nucleotides at position 191 to 191 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 206 in the user submitted sequence), (cause frameshift) ctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaAatgaacaatctgagAaaatgaggacacggcctgtattactgtgtaaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaacccctggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +17689 JY8QFUQ01AV3R5 unproductive (see comment) Homsap IGHV3-7*01 F 910 90.87 199/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [2.17.38.11] CAGGQRLA##DYW out-of-frame + stop codons in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 195 to 195 in the user submitted sequence), (cause frameshift); gcctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaGggggctcgagtgggtggCccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagcCcccgaggacacggctgtatatttctgtgcgggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaaggggcccatcggtcttcccccctggccgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaccggtgacggtgtcgtggaactcagg +17690 JY8QFUQ01BS2NT productive (see comment) Homsap IGHV3-66*02 F (see comment) 763 84.51 180/213 nt 84.04 179/213 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-21*01 F 3 8 7 11 8.7.11 [1.16.38.11] CARHLMVYALDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,51% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) ctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaggggctggagtgggtctcagtcttattagtactggcactgcatactacgcagactccgtgaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17691 JY8QFUQ01BFI2P productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLESVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagtccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +17692 JY8QFUQ01CGYG5 No results +17693 JY8QFUQ01CKFA2 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 700 84.54 164/194 nt 8 8 X 8.8.X [1.17.30.X] null + No rearrangement found Low V-REGION identity (84,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcg +17694 JY8QFUQ01AP042 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 3 8 8 21 8.8.21 [1.16.38.11] CAKYVEGWSYTGGYYNSYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) ttctggattcgcctttagccgttatgccatgacttgggtccgccagactccagggagggggctgagtgggtctcaggtctcagtggtagtggtgatagcacatacactcaaaactccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggaggggtggtcatatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17695 JY8QFUQ01BH8GS unproductive (see comment) Homsap IGHV3-9*01 F 440 90.65 97/107 nt 89.72 96/107 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 X 16 8.X.16 [1.15.11.11] CAKDGSAIPVTGTYFEYW in-frame - stop codons in FR2-IMGT, from codon 54 of V-REGION: 109 nucleotides (from position 74 in the user submitted sequence), (cause frameshift) tctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggaatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17696 JY8QFUQ01CK3OJ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1035 97.7 212/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame + gtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +17697 JY8QFUQ01B90TR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +17698 JY8QFUQ01C5W8H productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 897 90.0 198/220 nt 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [2.17.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); agcctccgaattcatccttgacagttatgccatgagttgggtccgccaggCccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17699 JY8QFUQ01C0OJR productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 673 79.81 170/213 nt 78.87 168/213 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 97 in the user submitted sequence), (do not cause frameshift) tctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaAGggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17700 JY8QFUQ01A8BTW productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 701 80.93 174/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [1.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame + Low V-REGION identity (80,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17701 JY8QFUQ01CJMO2 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 826 87.79 187/213 nt 87.32 186/213 nt Homsap IGHJ6*02 F (see comment) 157 72.58 45/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.37.11] CAREKGSGPPN#GMDVW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 187 in the user submitted sequence), (cause frameshift) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagcccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccaacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17702 JY8QFUQ01BQAXH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcccctttagcaactatgacatgaattgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggtttcttcccccag +17703 JY8QFUQ01CFF15 productive (see comment) Homsap IGHV4-4*07 F (see comment) 774 84.33 183/217 nt 83.41 181/217 nt Homsap IGHJ4*03 F 195 89.58 43/48 nt Homsap IGHD3-3*02 F 3 8 7 16 8.7.16 [2.17.38.11] CARSGYTSIVGVREFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 27 of V-REGION: 'C' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'GATAAA' (6 nucleotides at position 24 to 29 in the user submitted sequence), (do not cause frameshift); tgtctctggCgggccccatgactGATAAAaattactattggagttggatccggcagcccgccgggaagggactggagtggctcggacgtgtttatggtagcgggagcacaagctccaatccctccgtcaggagtcggatcaccatgtcaatatacacgtctatgaaccaattctccctgaggttgagttctgtgaccgccgcggacacggccgtctattattgtgcgagatcaggttatacttccattgtcggagtgagggagtttgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17704 JY8QFUQ01CEDV7 unknown (see comment) Homsap IGHV3-11*01 F (see comment) 752 83.03 181/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. gctctggattcaccctcagtgactacagtatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatacatcagccgaagtggaagtaatgtggaaactgcggactctgtgaggggccgattcaccgcctccagggacaccgccaataattcactgtttctgcggatgaatagcctgacagtcgaggacacggccctctattactgtgcgagagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17705 JY8QFUQ01APUXY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtatgaaccctgatggaagtactataagctacatggactccctgaagggccggctcaccatctccagagacaacgccaagaacacgttgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaaggggtggtttggagcccgtagattactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17706 JY8QFUQ01AJ9K5 productive Homsap IGHV3-74*03 F 914 91.28 199/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKVDSDGWHGTIDRW in-frame + cctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggatagcgatggctggcacggaacaatagaccgctggggccagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17707 JY8QFUQ01ADHC7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccatggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17708 JY8QFUQ01CGOZX No results +17709 JY8QFUQ01BAGHH productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17710 JY8QFUQ01DGD1O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 861 88.18 194/220 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAKCKAPGKVDWFDPW in-frame - agcctctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagcgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctggtaaggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17711 JY8QFUQ01CFX3B productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-11*01 ORF 2 8 7 17 8.7.17 [1.17.38.11] CARVGRSVGYSDSGWFDPW in-frame + tctctggtggctccatgagtagttactactggaactggattcggcagcccccagggaagggactggagtggattgggtatatctattacactgggatcaccaactacaatccctccctcaagagtcgagtcaccatgtcaatagacacgtccaggaagcagttctccctgaccctgacctctgtgaccgctgcggacacggccgtctatttctgtgcgagagtcggccggagtgtgggctacagtgactctgggtggttcgacccctggggccagggaaccctggtcaccgtctcctcaccatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17712 JY8QFUQ01B11DU productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 3 8 8 20 8.8.20 [1.17.38.11] CARLPYIVVLTNIISPTYFDFW in-frame - tttctggatacagttttaccagttactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctgctgactctgataccagatacagcccgtccttccaaggccaggtcagcatctcagccgacaagtccatcgacaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgcggctgccatatattgtggtgctgactaatataatctccccaacctactttgacttctggggccagggaacccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17713 JY8QFUQ01DISCP productive (see comment) Homsap IGHV4-61*02 F 849 87.0 194/223 nt 85.65 191/223 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [2.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 118 in the user submitted sequence), (cause frameshift) tgtcgtctggtgactGccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattAgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17714 JY8QFUQ01AKIRH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17715 JY8QFUQ01ASUWR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'GC' (2 nucleotides at position 49 to 50 in the user submitted sequence), (cause frameshift); cgtctacattcgcctttagcaactatgccatgagctgggtccgccaggGCtccgagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17716 JY8QFUQ01AQ3RI No results +17717 JY8QFUQ01AKROJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*01 F 2 8 8 9 8.8.9 [1.17.38.11] CARGGTDFDYW in-frame + Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttacatttagtgattataatatgaattgggtccgccgggctccagggaaggggctggaatatgtcgcaaccattacaactgggagtggtcaaatctactacagtgactcagtgaggggccgcttcaccatctctagagacgacgccaagaattcactttatctgcagatgaacaacctgagaggcgaggacacggctgtctatttttgtgcgagaggggggactgattttgactattggggccagggaaccctggtcaccgtctcctgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +17718 JY8QFUQ01B6SLF productive Homsap IGHV3-64*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + tctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17719 JY8QFUQ01BF98P No results +17720 JY8QFUQ01AQEWR productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 833 87.16 190/218 nt 86.24 188/218 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARLRSFGDYPLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggGggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccCctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17721 JY8QFUQ01CL96A productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17722 JY8QFUQ01C2L83 No results +17723 JY8QFUQ01BU1G8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctccaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17724 JY8QFUQ01CQR6E productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17725 JY8QFUQ01CE18D No results +17726 JY8QFUQ01CAKWX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame + ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +17727 JY8QFUQ01BISKJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 940 93.06 201/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + tctggattcacctttaccaactgtggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtctccccctgcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17728 JY8QFUQ01CS5J5 unproductive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGGW*R##LDYW out-of-frame - stop codons in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); cctctggattcacctTttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17729 JY8QFUQ01AFKEB productive Homsap IGHV1-8*02 F 822 87.38 187/214 nt Homsap IGHJ2*01 F 193 84.91 45/53 nt Homsap IGHD2-21*02 F 2 8 8 16 8.8.16 [0.17.38.11] CTTKFGSDWQSDWYFHVW in-frame + tggagacacattccccagccatgacatcaactgggtgcgacaggccactggagaagggcttgagtggatgggacggatgaaccctaagactggtgacacaagctttgcacagaagttccacgatagagtcaccatgatcagtgacacctccataagtacagtgtacatggagctgagtagcctgagatctgaagacacggccatttactattgtacgacaaaattcgggagtgactggcaatcggactggtacttccacgtctggggccgtggcacctcggtcaccgtctcctcagcatcccgaccagcccaaggtcttccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +17730 JY8QFUQ01CXFN5 productive (see comment) Homsap IGHV3-72*01 F 1093 98.67 222/225 nt 98.22 221/225 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [2.17.38.11] CLRPPRYDPWG in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gcctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaAaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctgggggccagggggacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17731 JY8QFUQ01AJ0TB No results +17732 JY8QFUQ01ALVXP No results +17733 JY8QFUQ01BPCFK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDRMIHTMRGAFDMW in-frame - ctctggattcaccttcagaaccaatgccatgaactgggtccgccaggctccagggaaggggctggagtggatctcagttattaatggtcccggtgatatcacatactacgcagactccgtgaagggccggttcaccatgtcccgagacaattccaaggacacgttgtatttgcaaatgatcagcctgagaggcgaggacacggccatatattactgtgcaaaagatcgtatgatacacacgatgaggggagcttttgatatgtggggccgagggacaatggtcaccgtctcttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacggcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17734 JY8QFUQ01B02W0 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17735 JY8QFUQ01AZEZ8 No results +17736 JY8QFUQ01DC610 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 955 93.15 204/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARRPSGSHWRLDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 76 of V-REGION: 'CC' (2 nucleotides at position 134 to 135 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 82 of V-REGION: 'A' (1 nucleotides at position 154 to 154 in the user submitted sequence), (cause frameshift); ggttctggatacagttttaccaacttctggatcggctgggtgcgccagatgcccggggatggcctgcagtggatggggatcatccatcctggtgactctgataccagatacagcccgtccttccaaggccaggCCtcaccatttcagtcgacaAagtccaccaacaccgcctacctgcagtggagcagcctgaaggcctcggacagcggcatctattattgtgcgagacggccgagtgggagtcattggagacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17737 JY8QFUQ01CHTSU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17738 JY8QFUQ01ADZAX No results +17739 JY8QFUQ01BEU17 productive Homsap IGHV3-48*02 F 891 90.32 196/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [1.17.38.11] CARGQKWLQVLRWFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17740 JY8QFUQ01B50HH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 103 62.9 39/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggcccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17741 JY8QFUQ01CIMV8 unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F (see comment) 373 64.56 133/206 nt 64.08 132/206 nt 8 7 X 8.7.X [1.17.34.X] null - No rearrangement found Low V-REGION identity (64,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift) cgtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17742 JY8QFUQ01BILUG unknown (see comment) Homsap IGHV3-11*01 F 943 93.9 200/213 nt 92.96 198/213 nt 8 7 X 8.7.X [1.17.37.X] null - No rearrangement found in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 120 in the user submitted sequence), (cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgagggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17743 JY8QFUQ01AP8B1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggcgtggagtggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17744 JY8QFUQ01BGZB0 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17745 JY8QFUQ01CHAEJ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaacctcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17746 JY8QFUQ01CIJU5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 886 90.28 195/216 nt 88.89 192/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); tctggatacagttttaacagttatgccatgacttggGgtccgccaggctccagggaaAggggctggagtgggtctcaactattagtggcactggtgGgtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17747 JY8QFUQ01BOYOR productive Homsap IGHV3-48*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDQSPGVAVAGPDYW in-frame + cgtctggattcacctttagtgattatgccttgaactgggtccgccaggctccaggaaaggggctggagtgggttgcatacattagaagtagcagtagtgtcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcaaagtccgggtgtagcagtggctggtcctgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17748 JY8QFUQ01B3VGR No results +17749 JY8QFUQ01DMR3X productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'TG' (2 nucleotides at position 55 to 56 in the user submitted sequence), (cause frameshift); gtttcgggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccTGggggaagggactggagtctgtctctgctttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17750 JY8QFUQ01AHMDP productive Homsap IGHV3-7*01 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame + gctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17751 JY8QFUQ01AEMFS No results +17752 JY8QFUQ01BWS44 productive (see comment) Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt 81.11 176/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggGggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17753 JY8QFUQ01C6RK2 No results +17754 JY8QFUQ01A46X0 No results +17755 JY8QFUQ01C56PW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +17756 JY8QFUQ01B2QIV unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 435 76.67 115/150 nt 8 7 X 8.7.X [1.17.16.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01B2QIV ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (76,67% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactacttccccgaaccggtgacggtgtcgtggaactcag +17757 JY8QFUQ01AZKV6 No results +17758 JY8QFUQ01COXAV productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 955 93.15 204/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 108 to 108 in the user submitted sequence), (cause frameshift); gcctccggattcaccGtttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaAactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17759 JY8QFUQ01BSS1N productive Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17760 JY8QFUQ01AMPZY productive Homsap IGHV1-69*06 F, or Homsap IGHV1-69*10 F or Homsap IGHV1-69*14 F 804 86.45 185/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-8*02 F 3 8 8 22 8.8.22 [0.17.38.11] CARGGKSPRRDIIQGVTVDALDLW in-frame + tggagacaccttcagtagccaagccatcagctgggtgcgacaggcccctggacaaggacttgagtggatgggcgggatcatccctatttttgatatgacgaggtacccacagaggttcgagggcagaatcacgattaccgcggacacgtccacgaccacactttacatggaactgagcagcctgaggtctgaggacacggccgtgtatttttgtgcgagaggcgggaagagtcctcgtcgtgatattatacagggggtgactgttgatgctcttgatctctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17761 JY8QFUQ01CDYHQ productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcctcctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17762 JY8QFUQ01ASPTX No results +17763 JY8QFUQ01BGFCA productive (see comment) Homsap IGHV3-7*01 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD4-23*01 ORF 3 8 8 12 8.8.12 [0.17.38.11] CARGTSVDPGIDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'GG' (2 nucleotides at position 55 to 56 in the user submitted sequence), (cause frameshift); tggattcacctttagtaattattggatgcactgggtccgccaggtttcaggggaGGggggctggagtgcgtggccaccataaacgaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactctctgtttttgcagatgaacagcctgagagccgaggacacggctgtctactactgtgcgagagggacctcagtggacccggggattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17764 JY8QFUQ01BMHY7 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 951 92.73 204/220 nt 92.27 203/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 7 10 10 7.10.10 [0.17.38.11] CTHLREEMSYEW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) ctggagtcaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17765 JY8QFUQ01A045O unproductive Homsap IGHV3-48*01 F 1065 99.53 213/214 nt 99.07 212/214 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [0.16.38.11] CASNFWSGSPG##YYYGMDVW out-of-frame - in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) ctggattcaccttcagtagctatagcatgaactgggtccgccaggctccaggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgaatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17766 JY8QFUQ01DGR8A productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17767 JY8QFUQ01C7FHX No results +17768 JY8QFUQ01B3Y86 unproductive Homsap IGHV3-11*01 F 963 94.01 204/217 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD2-21*01 F 1 8 8 X 8.8.X [1.17.38.11] CAREYSSGEKGWF#PW out-of-frame - ctctggattcaccttcaatacctactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcacacattagtagtagtggcagtgtcacatactacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaattcactgtatctgcaaatgaacagcctgagagccgagggcacggccctgtattattgtgcgagagaatacagtagtggtgaaaagggctggttcgaccctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +17769 JY8QFUQ01AOIG1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 95.19 198/208 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 6 8 15 6.8.15 [X.17.38.11] CARLCGNDCRNDVFDIW in-frame - caccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17770 JY8QFUQ01A006G productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtactcattactattggggctggatccggcagGcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +17771 JY8QFUQ01B6WLI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 7 12 8.7.12 [1.17.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17772 JY8QFUQ01CH00N unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17773 JY8QFUQ01DBLUE No results +17774 JY8QFUQ01BNROR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 833 87.16 190/218 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD3-16*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASLNTHAGPGAERSAFDVW in-frame + cctctggattcatcttcagtaactatagaatgaactgggtccgtcaggctccagggaaggggctcgagtgggtctcgtccatcaccagttccagtagttacatctactatgcagactcggtgacgggccgattcaccatctccagagacaactccaaggggtcactctatctgcacatgaacgaccttagggccgaagacacggctgtctattactgtgcgagcctaaacacgcacgcgggaccgggagccgagaggtctgcttttgatgtctggggccgagggacaagggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +17775 JY8QFUQ01C7M5B productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [1.17.38.11] CACYFDSNGFFDYW in-frame + ttctggatacgtctttccctcctactggatcgcctgggtgcgccagatgcccggtaaaggcctggagtggctgggaaccatctatcccggcgactctgacaccacatacagcccgtcattccaaggccaggtcaccatgtcagtcgacacgtccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacagcgccatttactattgtgcgtgttattttgatagtaatggtttctttgactactggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +17776 JY8QFUQ01CF7L2 productive Homsap IGHV3-7*03 F 878 89.45 195/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccgccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17777 JY8QFUQ01B6GID productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17778 JY8QFUQ01CKQ1C productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 1002 96.73 207/214 nt Homsap IGHJ1*01 F 170 80.77 42/52 nt Homsap IGHD6-19*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARPDGGNGWAAKYFQMW in-frame - ctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatgtttagcggtggtggcacaaactacgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacactgtatcttcaaatgaacagcctgagagccgcggacacggccgtgtattactgtgcgagacctgacggaggcaatggctgggccgcaaagtactttcagatgtggggccagggcacccttctcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17779 JY8QFUQ01CA6MQ productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17780 JY8QFUQ01AROW2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKEIAVSGEGALDFW in-frame + cctctggattcaccttcagtaactatagcatgagctgggtccgccaggctccagggaaggggccggagtgggtctcagctattactggtcttgatggtagaacattctacgcagactccgtgaagggccgtttctccatctccagagacaattccaagaacacgttgtatttgggaatgaacagcctgagagccgaggacacggccgtatattattgtgcgaaagagatagcagtgagtggtgagggggcgttggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctttcccca +17781 JY8QFUQ01BDWRF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.16.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccaggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +17782 JY8QFUQ01DTB3E unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 101 95.45 21/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggattcaccttaagtga +17783 JY8QFUQ01CQKI1 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame + tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccccca +17784 JY8QFUQ01A4ILH productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cgtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggGggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17785 JY8QFUQ01CFZJT productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17786 JY8QFUQ01AROWV productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 728 82.33 177/215 nt 81.4 175/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 46 of V-REGION: 'CCAG' (4 nucleotides at position 53 to 56 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccCCAGgggaaggggactggagtggattgGgggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17787 JY8QFUQ01BGKA2 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 878 88.99 194/218 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD2-2*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARYCSSDSCQGYHDAFDVW in-frame - cttctggatacatcttcacgaaccactggatcggctgggtgcgccagatgccgggtagaggcctggagtggatggggatcatctatcctggtgactccgattccagatacggcccgtccgcccaaggccaggtcaccttctcagtcgacaagtccatcgccaccgcctaccttcagtggagtagcctgaaggcctcggataccgccacgtactactgcgcgagatattgtagtagtgacagctgccaagggtaccatgatgcttttgatgtctggggccaagggacaatggtctccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17788 JY8QFUQ01CSDQW productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17789 JY8QFUQ01C20A3 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 826 86.04 191/222 nt 85.59 190/222 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [2.17.38.11] CVRHVRRFWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctctaatgggctccatcagcCggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17790 JY8QFUQ01AH797 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt 94.42 203/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcgatagttactacCtggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17791 JY8QFUQ01AQTMT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17792 JY8QFUQ01CUJHO No results +17793 JY8QFUQ01AC3NO No results +17794 JY8QFUQ01CEOCK productive (see comment) Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt 81.19 177/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggGggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17795 JY8QFUQ01CO7NK No results +17796 JY8QFUQ01BIGED productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFHYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttcactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17797 JY8QFUQ01BALQI unproductive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARERGNSYGEIDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggcccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagcccgccctgggctgcctggtcaaggactacttccccagaaccggtgacggtgtcgtggaactc +17798 JY8QFUQ01CTLV7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17799 JY8QFUQ01B7OCB unknown (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.14 211/215 nt 8 7 X 8.7.X [1.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); tctctggtggctGccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtncgagactgggggccccggttcgggggactactatggggccagggaaccctgggtcaccnnctccctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17800 JY8QFUQ01BDW1A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 995 95.41 208/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17801 JY8QFUQ01CETVH unproductive Homsap IGHV3-72*01 F 1078 98.65 219/222 nt 98.2 218/222 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.16.38.11] CLRPPRYD#PG out-of-frame + in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17802 JY8QFUQ01BF5Z7 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-71*03 P or Homsap IGHV3-72*01 F 283 88.73 63/71 nt 8 X X 8.X.X [1.14.X.X] null + No rearrangement found ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtggg +17803 JY8QFUQ01BFNMT unknown (see comment) Homsap IGHV3-7*01 F 1031 96.79 211/218 nt 95.41 208/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); cctctggattcaggtttagGcatctattggatgagctgggtGccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgTtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17804 JY8QFUQ01C08HE unproductive Homsap IGHV4-61*02 F 1005 95.45 210/220 nt 95.0 209/220 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-22*01 F 3 10 7 X 10.7.X [1.17.38.11] CARGSTYYYDTSAYYYFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtggtagttTtctactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtgtctatgccagtggaaccaccaagttcaacccctccctcaagagtcgagtcactttatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggccgtgtattactgtgcgcggggttcgacatattactatgatactagtgcttattactactttgactactggggcccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +17805 JY8QFUQ01BH4MR productive Homsap IGHV3-7*03 F 846 88.02 191/217 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREKGSGPPTGMDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17806 JY8QFUQ01BUNFI productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17807 JY8QFUQ01A8JZF productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + gctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +17808 JY8QFUQ01CD41O productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 894 91.12 195/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-18*01 F 1 8 8 15 8.8.15 [0.17.38.11] CAIVDTNLVSATGKDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacaccttcagcaactactatagacactgggtgcgacaggcccctggacaagggcttgagtggatgggaatgatcaaccctagtagtgattacaaatattacgcacagaaatttcagggcagagtcaccatgaccagggacacgtccacgagcacagtcttcatggagctgagtagcctgagatctgacgacacggccgtgtattattgtgcaatagtggacacaaatttggtttcggcgaccggtaaagactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +17809 JY8QFUQ01BTS0O productive Homsap IGHV3-23*05 F (see comment) 439 81.82 108/132 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 X 6 16 X.6.16 [X.X.38.11] CVRYDYSRLHRSNYFGPW in-frame - Low V-REGION identity (81,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctctggattcaccttcatcagttatgactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17810 JY8QFUQ01C9F9A unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CARGHSYYVSSGPDY## out-of-frame - in FR2-IMGT at codon 50 of V-REGION: 'T' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); agcctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctTggagtgggtctcagttattagtggaagtggtgataccacatcgtacgCcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactgggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17811 JY8QFUQ01CS2FP No results +17812 JY8QFUQ01CARZ1 productive Homsap IGHV4-39*02 F 983 94.12 208/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.17.38.11] CARIVVRQFDQW in-frame + tctctggtgactccatttccagtactagttattactggggctgggtccgccagcccccagggaaggggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17813 JY8QFUQ01DSA7F unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17814 JY8QFUQ01A4LRG productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggcatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17815 JY8QFUQ01DC9BI No results +17816 JY8QFUQ01AM2GA unproductive (see comment) Homsap IGHV3-74*03 F (see comment) 707 80.73 176/218 nt 79.36 173/218 nt Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRGNHWLEGG*LL# out-of-frame - stop codons Low V-REGION identity (80,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 206 to 206 in the user submitted sequence), (cause frameshift); cctctggaGttcaacgtcagtggatactggatgcactgggtccgccaagtgccagggaaggggctggtatGgggtctctaggctttcggatgatgaaattactataacttacgcggactttgtggagggccgattcaccatctccagagacaacgccaggaacgaggtctatctgcaaatgaatgatttgagagtcgacgatacgGgctgtatacttttgtgtgagggggaaccactggctggaggggggttgactactgggggccaaggcgccctcgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccc +17817 JY8QFUQ01AWTW0 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17818 JY8QFUQ01AM8JL productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17819 JY8QFUQ01BWE2P productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagtacacactacgcggaccccgtgcagggccggttcatcatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17820 JY8QFUQ01CNBQ8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17821 JY8QFUQ01BP7D4 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD2-8*02 F 2 8 8 24 8.8.24 [1.17.38.11] CVRAAGYCPGGDDCYKIGTHDSLDIW in-frame - gtctggattcaccttcagtacctatggcacacattgggtccgccaggctccaggcaaggggctggactgggtggcagttagttggcatgatggaagtcaggaatattatgcagactccgtgaggggccgattcactgtctccagagacaattccaagaacacggcatatctgcatatgaatgtcctgagaggcgaagacacggctgtctactactgtgtgagagcggcggggtactgtcctggtggtgatgactgctacaagatcggaactcatgactcccttgatatctggggccgaggggcagttgtctccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17822 JY8QFUQ01AZRKU productive (see comment) Homsap IGHV3-7*03 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 7 8 8 7.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctccggattcattttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17823 JY8QFUQ01AZYDF productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDLSTSGFDAIDIW in-frame + ctctggattcaccttcaatctctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatctcatatgatggaaataataaatactatgcagactccgtgaagggccgattcatcatctccagagacaactccaagaatctgctatatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgaaagatttgagtactagtggctttgatgctattgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17824 JY8QFUQ01AVLNX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 806 85.78 187/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaagccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactc +17825 JY8QFUQ01B7XTY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaacctcaatacctttggcatgaactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17826 JY8QFUQ01A6DZT productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 77 of V-REGION: 'G' (1 nucleotides at position 135 to 135 in the user submitted sequence), (cause frameshift); cctctggattcacctttaccaactatggcatgagttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcGaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17827 JY8QFUQ01A1PBD productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*06 F 919 91.32 200/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAKDKGLRYFDYW in-frame - gcgtctggaatcaccttcagtgcctctggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcttttataaggtctgatggaagcgatgaatactttgcagactccgtgaagggccgattcagcatctccagagacaattcgaagaacacggtgtatctccaaatgaacaccctgagagccgaggacacggctatgtattactgtgcgaaagataaggggctacgatactttgattattggggccagggaaccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17828 JY8QFUQ01AHNBF productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagGaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17829 JY8QFUQ01CBMG4 No results +17830 JY8QFUQ01BHPA3 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 92 52.31 68/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +17831 JY8QFUQ01AW9GE productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 758 82.81 183/221 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD3-3*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARRWSGTYPFASW in-frame + Low V-REGION identity (82,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctcactcagaagtagtagtcaccattggggctggattcgtcagtcccccgggaaggggctggagtggcttgggactgtcgactttcgtgggaccacccactacaacccgtccctcatgggtcgactcacgatatccgtcgacgcgcccaagagtcaaatgtccctgcacttgagctctgtgaccgccgcagacacggctttttacttctgtgcgagacgctggagtgggacttatccgtttgcctcctggggccagggcatcccggtcatcgtctccccagcttccaccaagggcccatccgtcttcccccgtggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +17832 JY8QFUQ01AL21Q productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDPSGSGWAFESW in-frame + cgtctggattccctttcagtagagatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatggtatggtatgatggaagtaatacacaccatgcagattccgtgaagggccgattcatcatttccagagacaattccaagaataaagtgtatctgcaaatgaacagtctgagagacgaggacacggctgtctattattgtgcgagagatccgagcggcagtggctgggcctttgagtcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17833 JY8QFUQ01BXFGU No results +17834 JY8QFUQ01CZMSL No results +17835 JY8QFUQ01AQ6RF productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 14 8.8.14 [1.17.38.11] CATDRKYSGVRGDDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); ctctggattcaccttcaggaactatgctatgcactgGggtccgccaggctcctggcaaggGggctagaatgggtggcttttatatcatatgatggaagtagtcaatactacgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacactttatctgcaaatgaacagcctgagaggtgacgacacggctgtgttttactgtgcgacggaccggaaatatagtggtgtacgaggcgatgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaaccgtggtccgtcgcatgcctggtccagggcttcttcccc +17836 JY8QFUQ01CJ5H7 productive Homsap IGHV3-9*01 F (see comment) 759 84.11 180/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [0.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17837 JY8QFUQ01AGZ50 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDREDSSGYYFFRDGFDIW in-frame + ctctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctccggtattggtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagatcgtgaagatagtagtggttattacttcttccgtgatggttttgatatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17838 JY8QFUQ01ASHYE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17839 JY8QFUQ01DMUBJ productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17840 JY8QFUQ01DQ53C productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17841 JY8QFUQ01CMFGZ productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 977 96.65 202/209 nt 96.17 201/209 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 6 8 16 6.8.16 [X.17.38.11] CARQIDYGDFSRHGLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); acaactttaccggctactggatcggctgggtgcgccagcggcCccgggaaaggcctggagtggatggggatcatctatcctggtgactctgataccagatacagcccatccttccaaggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccgtgtattactgtgcgagacaaatagactacggtgacttctctaggcacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17842 JY8QFUQ01CNALN productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17843 JY8QFUQ01B36L3 unproductive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-3*01 F 1 8 10 X 8.10.X [1.17.38.11] CITSFGGRSLAY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17844 JY8QFUQ01B7BKW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17845 JY8QFUQ01CDIVK productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagGggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17846 JY8QFUQ01C1QI4 productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1115 100.0 224/224 nt 99.11 222/224 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 3 8 10 12 8.10.12 [1.17.38.11] CTKCSVTIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); cttctggattcacctttggGtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaAaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17847 JY8QFUQ01BTJZQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 784 84.47 185/219 nt 83.56 183/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); tgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17848 JY8QFUQ01BKNNZ No results +17849 JY8QFUQ01CJKHK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame + ctctggattcacctttggcagccaagccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17850 JY8QFUQ01A02XZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgggtgtcgtggaactc +17851 JY8QFUQ01BM1C9 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatcCcataagtagtgGgtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17852 JY8QFUQ01DR9LO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + cctctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17853 JY8QFUQ01BP3M1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +17854 JY8QFUQ01DAPX2 productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKEEFDTGWTQPGDW in-frame + cctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +17855 JY8QFUQ01B8YQQ productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 954 93.55 203/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 14 8.8.14 [1.17.38.11] CATDRKYSGVRGDDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcaggaactatgctatgcactgggtccgccaggctcctggcaaggggctagaatgggtggcttttatatcatatgatggaagtagtcaatactacgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacactttatctgcaaatgaacagcctgagaggtgacgacacggctgtgttttactgtgcgacggaccggaaatatagtggtgtacgaggcgatgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17856 JY8QFUQ01CB1GG productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17857 JY8QFUQ01CS72X No results +17858 JY8QFUQ01CHUJH No results +17859 JY8QFUQ01AL2CW productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1115 100.0 224/224 nt 99.55 223/224 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 3 8 10 12 8.10.12 [1.17.38.11] CTKCSVTIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); cttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgAaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17860 JY8QFUQ01CNK50 productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1048 96.44 217/225 nt 96.0 216/225 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CARGSSRGGRSDVNYYELDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtCccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtattatgactatgcagtgtctgtccaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagctgaattctgtgactcccgaggacacggctgtgtattactgtgcaagagggtccagccgcggggggagatctgatgtgaactactatgagctggacttctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +17861 JY8QFUQ01B3TI8 productive (see comment) Homsap IGHV3-7*01 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD4-23*01 ORF 3 8 8 12 8.8.12 [0.17.38.11] CARGTSVDPGIDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tggattcacctttagtaattattggatgcactgggtccgccaggtttcagggaGgggggctggagtgcgtggccaccataaacgaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactctctgtttttgcagatgaacagcctgagagccgaggacacggctgtctactactgtgcgagagggacctcagtggacccggggattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17862 JY8QFUQ01BQ7U8 No results +17863 JY8QFUQ01AVZKB productive Homsap IGHV3-11*01 F (see comment) 756 83.41 181/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD2-8*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGRGRTNSPVDLW in-frame + Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccctcagtgactacagtatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatacatcagccgaagtggaagtaatgtggaaactgcggactctgtgaggggccgattcaccgcctccagggacaccgccaataattcactgtttctgcggatgaatagcctgacagtcgaggacacggccctctattactgtgcgagaggtagggggcgcactaatagtccagttgacctctggggccagggaacccaggtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttcccccag +17864 JY8QFUQ01DKN2O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 780 84.09 185/220 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD2-8*01 F 3 8 8 20 8.8.20 [2.17.38.11] CAKGASTAVMVSGTDCYGLDVW in-frame - Low V-REGION identity (84,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) agcctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaggggactggagtgggtcgcaactataagtggtggaggttatagtatatatgacgcagactccgtgaagggcaggttcaccatctccagagacaactccaagaccaccttgtttctggaaatgaaaagtctgagagtcgatgatacggccgtctattactgtgcgaaaggggcctcgactgcagtaatggtgtctggaacagattgttacggtttggacgtctggggccacgggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc +17865 JY8QFUQ01BVFET productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 870 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - agcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17866 JY8QFUQ01ASA07 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17867 JY8QFUQ01B8EMT productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17868 JY8QFUQ01C8GT7 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 846 88.02 191/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-2*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDRTLHTPAQMFYYGMDVW in-frame - atctggattcaccttcagttcttatagtgtaaactgggtccgccaggctccagggaagggcctagagtttgtctcatacattgatagtagtggttctaccatatactacgcagactctgtgaagggccgattcaccatctctagagacaatgcccagaactcactgtttctgcaaatgaacaacctgcgagtcgacgacacggccgtatattactgtgcaaaagaccggacacttcacacacccgctcagatgttttactatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatctccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17869 JY8QFUQ01BP9BO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17870 JY8QFUQ01C2XTT unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 120 53.9 76/141 nt 10 7 X 10.7.X [1.17.11.X] null - No rearrangement found stop codons tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17871 JY8QFUQ01ARQLK unproductive (see comment) Homsap IGHV1-2*02 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [0.17.38.11] CARGGDDVGTIIGE##DSW out-of-frame + stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 69 of V-REGION: 'A' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); tggatacacgttcaccgactactatgtccactgggtgcgacaggcccctggacaagggcttgagtggatggcgtggatcaaccctaacattggtgtcaccaagtctgcacAaaaattttcagggcagggtcaccatgaccagggacacgtccatcagcacagccttcatggagctgagcagcctgagatctgacgacacggccgtttattactgtgcgagagggggggacgacgtgggaactattattggggaatcttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17872 JY8QFUQ01B4YIL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcacgttccccgaaccggtgacggtgtgcgtggactca +17873 JY8QFUQ01BHXQZ unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +17874 JY8QFUQ01CDG0F productive (see comment) Homsap IGHV3-48*02 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARDMIIFGGALDNW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); gcctctggattcaggtttagcatctattggatgagctgggtccgccagggtccagggaaggggctggagtggatttcacacattaGggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgggagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggagcccttgacaactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17875 JY8QFUQ01CZKAD productive (see comment) Homsap IGHV4-39*03 F 915 90.87 199/219 nt 89.95 197/219 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'G' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); ctccggtggctccatcaacagtagaaattattattgGgggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactGacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtttaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17876 JY8QFUQ01CNTRA productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-13*01 F 1 10 7 18 10.7.18 [1.17.38.11] CARDRYVVDRSWYGNFFDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtggtacttactactggagctggatccggcagcccgccgggaaggcactggaatggattggacatatctctaccagtgggagtaccacctacaaccCcctccctcaagagtcgagtcaccatatcagctgacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcagacacggccgtgtattattgtgcgagagatcgatatgtcgtggacaggagctggtacggcaactttttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccg +17877 JY8QFUQ01A91KA No results +17878 JY8QFUQ01C7T2H productive (see comment) Homsap IGHV3-11*01 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17879 JY8QFUQ01CBQC2 productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17880 JY8QFUQ01B5UZM unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F 194 56.98 98/172 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found ctctggattcaccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaatggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17881 JY8QFUQ01DB5ES productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1023 96.36 212/220 nt 95.45 210/220 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [2.16.38.11] CARDTLEVVSNMDDAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) cagcctctggattcaccGttcagtcgttatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17882 JY8QFUQ01CA8RY No results +17883 JY8QFUQ01CC5S0 productive (see comment) Homsap IGHV4-61*02 F (see comment) 740 81.9 181/221 nt 81.45 180/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERSISIGGAREFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,90% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); tcactggtggccccatgggcagtagtttatacttctggaattgggtccgacagcccgccgggaagagactggagtggatcggAcgtggtttatgatgatgggagtacccgctacaatccctccctcaggggtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaggttgagttttgtgaccgccgcagacacggcccgttattactgtgcgagagaacggagtatttcgattggcggagcgagagaatttgactcttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17884 JY8QFUQ01BX1Z6 unproductive (see comment) Homsap IGHV3-48*01 F 860 88.53 193/218 nt 87.61 191/218 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.16.38.11] CARASTFYYDGSGYRDA#FDIW out-of-frame - stop codons in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) agtctctggcttcagtttgagtacttataccatgaactggtccgccaggctccaggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgctttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17885 JY8QFUQ01BJXZO productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.37.11] CARGFSAWGQDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 213 in the user submitted sequence), (cause frameshift) ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctattctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17886 JY8QFUQ01AQQXF No results +17887 JY8QFUQ01BYI4A unproductive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ5*01 F 111 68.63 35/51 nt 8 8 X 8.8.X [1.17.38.11] CARDQVTEDY (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactgggccaggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17888 JY8QFUQ01AQAL7 productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17889 JY8QFUQ01AR91V productive (see comment) Homsap IGHV4-61*02 F (see comment) 779 84.4 184/218 nt 83.03 181/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 9 7 13 9.7.13 [1.17.38.11] CARAKDHDDYLVDPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 37 of V-REGION: 'CTT' (3 nucleotides at position 28 to 30 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 3 nucleotides (from position 27 in the user submitted sequence), (do not cause frameshift) tctctggtgcctccatcactagtggtaCTTactactggagttggttccggcagcccgccgggaagacactggaatgggttgggcgtatctatacaactgggagcacctattacaaTcccctctctcaaaagccgagtcaccgtttcagtcgacgagtcccagaatcagctcttcctggacctgacttctgtgaccgccgcggacacggccgtctacttctgtgcgcgagctaaggaccacgatgactacctggtcgacccctggggccaggggatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17890 JY8QFUQ01AV9KO unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt 86.92 186/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.16.38.11] CAREKGSGPPH#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17891 JY8QFUQ01CU257 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 758 82.81 183/221 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD3-3*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARRWSGTYPFASW in-frame + Low V-REGION identity (82,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctcactcagaagtagtagtcaccattggggctggattcgtcagtcccccgggaaggggctggagtggcttgggactgtcgactttcgtgggaccacccactacaacccgtccctcatgggtcgactcacgatatccgtcgacgcgcccaagagtcaaatgtccctgcacttgagctctgtgaccgccgcagacacggctttttacttctgtgcgagacgctggagtgggacttatccgtttgcctcctggggccagggcatcccggtcatcgtctccccagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17892 JY8QFUQ01A0TNI productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17893 JY8QFUQ01B93OB productive Homsap IGHV3-21*04 F, or Homsap IGHV3-23*01 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +17894 JY8QFUQ01A18L5 productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-3*01 F 1 8 8 20 8.8.20 [0.17.38.11] CARDHRSGALEWSHHYHGMDVW in-frame + tggttacatcttcacccactatggtatcaactgggtgcgccaggcccctggacaagggcttgagtggatgggatggatcagcgcctacagtggtaacacaaagtatgcacagaaggtccagggcagagtcaccatgaccacagacacttccacgagtacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagatcacagaagcggggctttggagtggtctcaccactaccacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +17895 JY8QFUQ01BUZXB No results +17896 JY8QFUQ01A4H9C productive Homsap IGHV3-48*02 F 896 90.37 197/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDHIWAFDFW in-frame + cctctggattcaccttcagtgactatagcatgaactgggtccgccagactccagggaagggggtggagtggatttcatacatcggccgtggtggtgatgggatatactacgcagactctgtgaagggccgaatcaccatctccagagacaatgccaagaactcactttttctgcaaatgaacaccctgagagacgacgacacggctgtgtattactgtgcgagagaccacatttgggcttttgatttctggggccaagggacaaaggttaccgtctcgtcagcatcccccgaccagccccaaggtcttcccgctgagcctcgaagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17897 JY8QFUQ01C4I62 productive (see comment) Homsap IGHV3-48*02 F 828 87.1 189/217 nt 86.64 188/217 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-16*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARGRYSYAHGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctccggattcacctccatctcctatggcatgcactgggtccgccagattccaggaaaggGggctggagtcggttgcatacattagtgatagtaatagcagcatatactatgcagactctgtgaagggccgattcaccatctcccgagacaaagacaagaagtcagtatatctgcaaatgagcagcctgagagacgaggacacggctatttattactgtgcgagggggcgatacagttatgctcacggaatggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17898 JY8QFUQ01ATCVI productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1020 95.52 213/223 nt 95.07 212/223 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-11*01 ORF 3 8 10 18 8.10.18 [1.17.38.11] CARHEGTPVSDVGGYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtggctctgctatgcactgggtccgccaggcttccgggaaagggctggaatgggttggccgtattagaagcagagcttacagttccgcgacagcatatgcagcgtcggtgaaaggcaggttcaccatttccagagatgattcaaagaacacggtgtatctgcaaatgaacagtttgaaaaccgaggacacggccgtgtattactgtgctagacatgaagggactccagtaagtgatgtaggtggatacggcatggacgtctggggccaagggtccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17899 JY8QFUQ01CZ3YD unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 935 91.07 204/224 nt 89.29 200/224 nt Homsap IGHJ6*02 F 157 72.58 45/62 nt Homsap IGHD4-11*01 ORF 3 8 10 X 8.10.X [1.17.38.11] CHYSPKRNLCNG#YFAMDVW out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 92 of V-REGION: 'A' (1 nucleotides at position 189 to 189 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'AC' (2 nucleotides at position 202 to 203 in the user submitted sequence), (cause frameshift); cctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaagGgggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcCccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaAacagcctgaaaaACccgaggacacagccgtgtattactgtcactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtcgtcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagcagcacctctgggggcacagcggccctgggctgcctggtccaaggactacttcccccgcaaccggtgacggtgtcgtggaaactca +17900 JY8QFUQ01B85V0 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 929 91.4 202/221 nt 90.05 199/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 10 7 11 10.7.11 [1.17.38.11] CARSYGFSRFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 64 to 65 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaccagtagtctttaccgctGggggctggatccgccagtccccagggGAaagggcctggagtggatagggaatatcttttatggtgggaccaCcctactacaacccgtccctcaagagtcgagtcaccttatccatagacacgtccaagagccagttctccctgaagctgtcctctgtgaccgccgcagacacggctctatattactgtgcgagatcgtacggtttctctcggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17901 JY8QFUQ01CLNWZ unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 617 94.85 129/136 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found ttctggatatagttttgccacctactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatgggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcacc +17902 JY8QFUQ01AZNQP productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt 87.21 191/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAGSGRDPYGINVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); gcctctggattcaccttGcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcatccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +17903 JY8QFUQ01BLQ3C productive Homsap IGHV3-7*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame + cctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttgcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttcccccag +17904 JY8QFUQ01BRSG2 unknown (see comment) Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 135 52.02 103/198 nt 8 6 X 8.6.X [1.17.33.X] null - No rearrangement found ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagccctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +17905 JY8QFUQ01CQPHJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctcgagcctccaccaagggcccatcggtcttcccccatggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17906 JY8QFUQ01AKVNJ productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [1.17.37.11] CAKSPSQVGYYLDCW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 77 of V-REGION: 1 nucleotides (from position 136 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccggcaaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcacatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17907 JY8QFUQ01CAEZS unproductive Homsap IGHV3-7*01 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSGYYSTGY## out-of-frame - ctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactgggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17908 JY8QFUQ01CLCEW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtgcgtggaactca +17909 JY8QFUQ01CH51T No results +17910 JY8QFUQ01C5K3P No results +17911 JY8QFUQ01AFRC4 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17912 JY8QFUQ01AWV4P No results +17913 JY8QFUQ01A8412 productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17914 JY8QFUQ01CQH14 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctctaagagcacctctgggggccaccagcggccctgggctgcctggtcaaggactcttccccggaaccggtgacggtgtcgtggaactcagg +17915 JY8QFUQ01AC8KF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17916 JY8QFUQ01DDNDA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17917 JY8QFUQ01DJQ7I productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 176 86.96 40/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.38.11] CSRLLEEW in-frame + cctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcccagggctnttcccc +17918 JY8QFUQ01DDEDC productive Homsap IGHV3-9*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDRKGSNWYYFENW in-frame + cctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17919 JY8QFUQ01DEFNK No results +17920 JY8QFUQ01CSO9O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17921 JY8QFUQ01CL0GK No results +17922 JY8QFUQ01BSXFG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARGVGATAEYFQYW in-frame + ctctggattcacctttagtaactatgccatgacctggattcgccaggctccagggaaggggctagagtgggtctcagttattagtggaagtggtggtactacatactacgcagactccgtgaagggccggttcaccatctccagagacaatcccaagaacacgctgtatttgcaaatgactagcctgagagtcgaggacacggccatatatttctgtgcgaggggagtgggggctaccgctgaatactttcaatactggggccagggcgccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17923 JY8QFUQ01CP3FT unproductive (see comment) Homsap IGHV3-9*01 F 882 89.86 195/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDLRRP##GMDVW out-of-frame + stop codons ctctggattcacctttgatgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtattagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcatcacatccagagacaatgccaagaactccatctatttgcaaatgaacagtctgagagatgacgacacggccttctacttctgtgcaaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccaaatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +17924 JY8QFUQ01DA6WQ productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [2.17.38.11] CTRGRSDAWELSDHW in-frame - cgtcgacgatgggtcctgcagaaactgcttctggagttggatccgccagtccccagggaaggggctggagtggattggggaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagtcgagtcaccatatcattagacacgtccaacaaccaagtctccctgaggttgagctctgtgaccgccgcggacacggctgtgtattactgtacgcgagggcgatccgacgcgtgggaattatcggaccactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +17925 JY8QFUQ01CPWZG productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'T' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccTggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgacttctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17926 JY8QFUQ01DBZJH productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +17927 JY8QFUQ01CH3WR productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagccctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17928 JY8QFUQ01A7KV1 productive Homsap IGHV3-74*03 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +17929 JY8QFUQ01AD2DE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1008 96.31 209/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYYYDNIPAHDTFDLW in-frame - ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacattgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgaagaagtactactatgataatattcctgcgcatgatacctttgatctctggggccaagggacaatggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17930 JY8QFUQ01A55FP productive Homsap IGHV3-7*01 F 1014 95.91 211/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - aggctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +17931 JY8QFUQ01CLFHV unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDNYGDY## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17932 JY8QFUQ01BH53J No results +17933 JY8QFUQ01B3MWL unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 945 93.09 202/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.17.38.11] CARKGPRRDGSLQQCDMDV* in-frame + stop codons Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctgaggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +17934 JY8QFUQ01CP16Y unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 879 89.09 196/220 nt 88.18 194/220 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD1-1*01 F 1 8 8 X 8.8.X [2.17.38.11] CARVGTFNWFG#PG out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); ggcctctggattcaGattttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtGcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctgggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17935 JY8QFUQ01BYDVO productive (see comment) Homsap IGHV3-11*01 F (see comment) 788 84.86 185/218 nt 84.4 184/218 nt Homsap IGHJ6*02 F (see comment) 220 83.87 52/62 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARYRGSYYDYGGVDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 81 of V-REGION: 'G' (1 nucleotides at position 147 to 147 in the user submitted sequence), (cause frameshift); cctctggcttcagattccgtgactactacatgacgtgggtccgccaggctccagggaagggtcttgagtggctttcctccatcagcagcggtagtaataccatccactactcagactcggtgaggggccgcttcaccatctccaggGgacaacaccaggaactcagtggatctgcaaatgaatagtctgagagccgaagacacggccgtctattattgtgcgaggtacagaggcagttactacgactatggcggtgtggacgtctggggccgtggcacctcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +17936 JY8QFUQ01DCEKZ No results +17937 JY8QFUQ01DHIOD unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift); caggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgCtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17938 JY8QFUQ01CCHKG productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame + cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttgcccccag +17939 JY8QFUQ01DLPO2 productive Homsap IGHV3-9*01 F 866 88.24 195/221 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [2.17.38.11] CAKDVTSESHFFALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) agccgtcgggattcaagtttgatgaatatgccatgcactgggtccggcgagttccagggaggggcctggagtgggtctcagttataagttgggatggtgatgacatcgcctatgcggactctgtgaagggccgattcagcatctccagagacaacgccaagaactccctgtacctggaaatgagcagtctgagagttgaggacacggccttctattactgtgcaaaggatgtcacatctgaaagtcacttcttcgctttggacgtctggggccaagggaccgcggtcaacgtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17940 JY8QFUQ01AKJVX productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1007 96.74 208/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAREDGSGRRHFDYW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccaggaaagggactggagtggattgggtatatcttttacactgggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17941 JY8QFUQ01B8IZ5 productive Homsap IGHV3-48*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17942 JY8QFUQ01B6KRJ unproductive Homsap IGHV3-30*01 F 869 88.99 194/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGSHQSE#YGLDVW out-of-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcgggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17943 JY8QFUQ01B2KOT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 842 87.61 191/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARDGEWEMLDHW in-frame - cctccggattcaccttcagtaggtattggatgtattgggtccgccaagctccaggcaaggggctggtgtgggtctcacgcattaaaagtgatgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacatatttttgtgcaagagacggggagtgggagatgcttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17944 JY8QFUQ01CWAUA productive Homsap IGHV3-7*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - ctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagccaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17945 JY8QFUQ01B85C7 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17946 JY8QFUQ01BKM45 productive Homsap IGHV1-24*01 F 993 96.26 206/214 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [0.17.38.11] CAIGAMATW in-frame + cggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +17947 JY8QFUQ01C270K unproductive (see comment) Homsap IGHV4-61*02 F 988 94.14 209/222 nt 93.69 208/222 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 2 10 7 X 10.7.X [2.17.38.11] CATVARLG#AFDIW out-of-frame - stop codons in FR3-IMGT at codon 95 of V-REGION: 'G' (1 nucleotides at position 194 to 194 in the user submitted sequence), (cause frameshift); gtctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgaGcccccgcagacacggccgtttattactgtgcgacagtggcgcgcctggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17948 JY8QFUQ01BWLVB productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + cctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtgggaactcagg +17949 JY8QFUQ01B4CN9 productive Homsap IGHV4-61*02 F 902 90.05 199/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 14 10.7.14 [1.17.38.11] CAREKVVIRPNWFDPW in-frame + tctctggtgactccatcaccagtggtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaatccctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagagaaaaagtagtgatccgtcccaactggttcgacccctggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggttttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17950 JY8QFUQ01A9MZY productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 806 85.78 187/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17951 JY8QFUQ01CM4HO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcattcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17952 JY8QFUQ01CIL71 productive Homsap IGHV3-11*01 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - gcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +17953 JY8QFUQ01C64G5 unknown (see comment) Homsap IGHV3-7*03 F 832 87.04 188/216 nt 86.57 187/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); tctggattcaTggtttagtaactattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagaaagatggtagtgagacttactatgtggaatctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagccagggaacccaggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17954 JY8QFUQ01C9V0T unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 882 89.4 194/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found ctctggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagagccgaggccctgccgctggccttcacacagaagaccatcgaccgcttggcgggt +17955 JY8QFUQ01A2WHC productive Homsap IGHV3-66*02 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame + ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcaccatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +17956 JY8QFUQ01BN73N No results +17957 JY8QFUQ01C9XLQ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 857 87.78 194/221 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD1-1*01 F 1 10 7 14 10.7.14 [1.17.38.11] CARELGNTERGIVDPW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcagcgacactagttatcactgggcctggatgcgccagcccccagggaagggcctggagtggattgctaatgttcattatactggcagcgcccactacaacccgtccctcaagagtcgagtcaccatactagtagacacgtcccagaatcagttctccctgatgctgagttctgtgaccgccacagacacggctgtgtattactgtgcgagggaacttggtaatactgagaggggaatcgtcgacccctggggccagggaatcccggtcagcgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17958 JY8QFUQ01DJNA6 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 820 86.3 189/219 nt 84.47 185/219 nt Homsap IGHJ6*02 F 187 79.66 47/59 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [2.17.38.11] CARRDSDFRMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 180 to 180 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 216 to 216 in the user submitted sequence), (cause frameshift); gtgtctggatatgactttagcagAattttggatcgcctgggtgcgccagatgcccgggaAaaggcctggagtggattggaatcatctatcctagtgactctgatacgagatacagtcccaccttccaaggccaggtcattatctcagccgacaagtccctcagtaccgcctacctacttTtttagcagtctgagggcctcggacaccgccatgtaCtttttgtgcgagacgtgattccgacttccgtatggacgtctggggccaggggaccacggtcaccgtgtctccaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17959 JY8QFUQ01CIRQ5 No results +17960 JY8QFUQ01BYE1J unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 995 95.41 208/218 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt 8 8 X 8.8.X [1.17.38.11] CAKLGVAATTWNFFDY (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17961 JY8QFUQ01DLFDG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [2.17.38.11] CMNELGYCSGGG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 205 to 205 in the user submitted sequence), (cause frameshift); gtttctggattcacttttagcagtcatatgatgagttgggtccgccaggctccagggaagggactggaatgggtctcaagtattcgtgccagtggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgctgtatttgcaaatgtacagcctgagagtcgaggacacgGgccttatattactgtatgaacgaactcggatattgtagtggtggggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17962 JY8QFUQ01B9EY0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17963 JY8QFUQ01AK37R No results +17964 JY8QFUQ01BI4OT unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 615 96.21 127/132 nt 94.7 125/132 nt 8 8 X 8.8.X [0.17.10.X] null + No rearrangement found in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagctactaTtttgcactgggtgcgacaggCcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcac +17965 JY8QFUQ01B5UDN unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [2.17.38.11] CAREKGSGPPH#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctgggttgaGccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17966 JY8QFUQ01BCQZG productive (see comment) Homsap IGHV3-7*01 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); cctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17967 JY8QFUQ01BX2MX productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt 97.24 211/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17968 JY8QFUQ01CNS8U productive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*11 F or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 795 85.51 183/214 nt 85.05 182/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [0.17.38.11] CVRVRDYEIGGDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); tggaggcgccttcagcacctttcatatcacctgggtgcgacaggcccctggacaagggcttgtctggctggggaatatcattcctaCtttttggaacagtcgactacgcacgggggttccagggcagagtcacgattaccgcggacgaatccaccaacacagcctacatggagttgagcagcctgacatctgaggactcagccgtctatttctgcgtgagagttcgtgactatgaaattggtggtgacttctggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17969 JY8QFUQ01CHOJJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17970 JY8QFUQ01BUCUZ unproductive Homsap IGHV3-48*01 F 1090 100.0 219/219 nt 99.54 218/219 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [2.17.38.11] CASRLRSSGGY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtagctatagcatgaactgggtccGgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17971 JY8QFUQ01B7ROZ productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame + ctctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgctggtcccagggcttgcttccccca +17972 JY8QFUQ01BTU9P productive Homsap IGHV3-64*02 F 917 92.09 198/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVTCGDYSYEYW in-frame - ctggattcgcctttagtggctattggatgagttgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17973 JY8QFUQ01CO6O1 No results +17974 JY8QFUQ01CNDXZ productive Homsap IGHV3-7*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + cctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctcag +17975 JY8QFUQ01CG1SW unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CVREGRGTAAYGLDV## out-of-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctgggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggcagcacctccgagagcaccagccgccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17976 JY8QFUQ01CAXLD productive (see comment) Homsap IGHV3-66*02 F 926 92.56 199/215 nt 92.09 198/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 7 17 8.7.17 [1.17.38.11] CSTPTYCRGGSCSQIFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift); cctctggattcaccgtcagtaactaccacatgGaggtgggtccgccaggctccagggaaggggctggagtgggtctcagttatttacagcggtggtagtacatattacatagactccgtgaagggccgattcaccatctcgagagacgattccgagaacacagtgtatcttcaaatgaagagcctgagagctgaggacacggctgtatattactgttcgacgcccacatattgtaggggcggtagctgttcccagatttttgactattggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17977 JY8QFUQ01CN9M7 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 926 92.56 199/215 nt 92.09 198/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 77 in the user submitted sequence), (cause frameshift) tctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggcgtggagtgggtctctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +17978 JY8QFUQ01ASQT0 productive Homsap IGHV3-7*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD6-13*01 F 1 8 8 22 8.8.22 [1.17.38.11] CVRVRWPQYSNTWYGANQDVFDIW in-frame + ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccgtctccagagacaactccaagaattcactgtatctccaaatgaacagcctgagagtcgaggacacggctatttattactgtgtgagagtccgctggccccagtacagtaacacctggtacggggccaatcaggatgtttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17979 JY8QFUQ01BYLXC unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 600 82.76 144/174 nt 82.18 143/174 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found Low V-REGION identity (82,76% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaggGggctggagtgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgc +17980 JY8QFUQ01BE0MA No results +17981 JY8QFUQ01AKM0W productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 904 91.2 197/216 nt Homsap IGHJ4*03 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAREWAASHFDHW in-frame + gctggattcaccttcagtggctttgctttgcactggctccgccaggctccagacaaggggctagagtgggtgggatttacatcatttgatgggagtaacagagactacgcagactccgtgaagggccgattcacgatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagacctgacgacacggctgtatattactgtgcgagagagtgggcagccagtcactttgaccactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17982 JY8QFUQ01B6RL8 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKKTL*FGDLF#YNFDYW out-of-frame - stop codons in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggagggggActggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaacattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17983 JY8QFUQ01CS8O3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD1-26*01 F 3 8 7 12 8.7.12 [2.17.38.11] CARWRSRSYDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) gcctctggattcacctttagcaactatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattacaagtggtggtagcacatactacgcaaactccgtgaagggccggttcaccgtctccagagacagttccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagatggcgtagtcggagctacgactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17984 JY8QFUQ01AKQ1X productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcca +17985 JY8QFUQ01AHMI8 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARVRGYYGGQYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17986 JY8QFUQ01B4BRQ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 858 89.25 191/214 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVSDLAGQKGSW in-frame - aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcggggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17987 JY8QFUQ01CCMUH productive (see comment) Homsap IGHV3-11*01 F 982 94.52 207/219 nt 94.06 206/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 81 of V-REGION: 'G' (1 nucleotides at position 148 to 148 in the user submitted sequence), (cause frameshift); gcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccaggGgacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17988 JY8QFUQ01B7TE7 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcagatttagcagctatggcatgagctgggtccgccaggctccaaaaaaggggctggagtgggtctcaggaattagtgcgaatggtggtagtataaattatgcagactccgtgaagggccgattcatcatctccagagacaattccaagaacacattgtttctgcaaatgaatagcctgagagccgaagacacggccgtatattattgtgcgaaagagatagcagtgagtggtgaggggcgtgacttctggccaggaacctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17989 JY8QFUQ01BFG6Q productive Homsap IGHV4-61*02 F (see comment) 596 74.66 165/221 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-10*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARECSNSKVGPRALDSW in-frame + Low V-REGION identity (74,66% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tttctggtggcccgatcaaaagtcctgattaccattggacgtggatccggcagcccgccgggaagggactggagtgggtcggacgtgtctatatgactggttatgtcgaccacaatccatccctctccgggcgtctcaccatgtctatcgacacctcgaagaatcaattttctatgacattgacctctgtgaccgccgcagacacggccctatatttttgtgcgagggagtgtagtaattcgaaggtcggaccgagagcgcttgattcctggggcccgggaagtctggtcaccgtatcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17990 JY8QFUQ01DJMUZ productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17991 JY8QFUQ01CZPRJ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 807 85.45 188/220 nt 85.0 187/220 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); agcctctgaattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatCgggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +17992 JY8QFUQ01BSUXU productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 966 94.86 203/214 nt 94.39 202/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaAaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17993 JY8QFUQ01C1RKP No results +17994 JY8QFUQ01BDM2X unknown (see comment) Homsap IGHV3-74*03 F 126 54.81 74/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +17995 JY8QFUQ01A8YO2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-17*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKEMIRYGDDVFGGLNVW in-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tctctggatttacctttagcagttatgccatgaactgggtccgccaggctccagggaaggggctgcagtgggtctctggtattagtggtggtggtgatgacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtgtattactgtgcgaaagaaatgatccgctacggggacgacgtttttggcggtctgaacgtctggggccaagggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +17996 JY8QFUQ01C7CT3 productive (see comment) Homsap IGHV3-30*01 F 864 88.94 193/217 nt 88.02 191/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'A' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggGggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagAaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +17997 JY8QFUQ01DS3DP unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*03 F 733 87.77 165/188 nt 87.23 164/188 nt 8 8 X 8.8.X [1.17.28.X] null + No rearrangement found in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 170 to 170 in the user submitted sequence), (cause frameshift); ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttCctgcaaatggacagtctga +17998 JY8QFUQ01DD91R productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 103 62.9 39/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +17999 JY8QFUQ01DJSA7 productive Homsap IGHV4-30-2*02 F, or Homsap IGHV4-55*06 P or Homsap IGHV4-59*01 F or Homsap IGHV4-59*02 F or Homsap IGHV4-59*03 F or Homsap IGHV4-59*07 F or Homsap IGHV4-59*09 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*03 F or Homsap IGHV4-61*07 F or Homsap IGHV4-61*08 F 162 94.59 35/37 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 X X 12 X.X.12 [X.X.12.11] CARAPGWMNPFDFW in-frame - ctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18000 JY8QFUQ01AFK3U productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - cctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18001 JY8QFUQ01CL67W productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 741 83.18 178/214 nt Homsap IGHJ6*02 F 179 77.05 47/61 nt Homsap IGHD2-15*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDKVISAGRDVW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CL67W ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagtttcactggttttaccgtgatctgggtccgccaggctccaaggaaggggctggaatggatctcatccgtcactactaatggtctcacgtactacgcagactcagtagagggccgattcaacatctccagggacaacgccaacaatttagtgtttctgcaaatgaacagcctgagagtcgaggacactggtgtatattattgtgcgagagataaagtgatctctgccggacgggacgtctggggccaagggaccacggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18002 JY8QFUQ01BMS5S productive Homsap IGHV3-7*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYYHYDMFGDYW in-frame + cctctggatttacttttagcaactattggatgacctgggttcgccaggctccagggaaggggctggagtgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgcatctgcaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgagagggtcgtattatcattatgatatgttcggcgactactggggccagggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +18003 JY8QFUQ01CBDJS productive (see comment) Homsap IGHV1-3*01 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacagcttcactaactacaatatccattgggtgcgccaggGcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18004 JY8QFUQ01AA0DL productive Homsap IGHV3-30*15 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame - ctctggattcacctttagtagatattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttatatcatacgatggaagtagaagaatctacgcagactccgtgaagggccgattcaccatctccagagacacttccaagaacacggtgtatctgcaaatgagtagcctgagacctgaggacacggctgtgtattactgtgcgagagatgagctgccttgggatacaatagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +18005 JY8QFUQ01DFPZY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame + ctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18006 JY8QFUQ01C17HE productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSGPSGYARYESMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); ctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggaggggcgtggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaGggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18007 JY8QFUQ01CDL1J productive (see comment) Homsap IGHV3-7*01 F 913 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); ctctggatttacttttaacaactattggatgacctgggttcgccaggntccagggaaggggctggaatgggtggccaacataaGaacaacatggaggtgaaacgtactatgCtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18008 JY8QFUQ01BPBJ6 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*02 F 3 8 8 13 8.8.13 [1.17.38.11] CARTRGATDANFEYW in-frame - gtggtggatacaccttttccaattactggatccactgggtgcgccagatgcccgggaaaggcctggagtggttggggatcatctatcctggtgactctgataccagatatagcccgtccttccaaggccaggtcaccctctcagccgacaggtccatcagtaccgcctacttgcagtggagcagcctgagggcctcggacaccgccgtgtattactgtgcgagaacgaggggagctaccgacgcaaactttgaatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18009 JY8QFUQ01BVBI3 productive (see comment) Homsap IGHV3-11*01 F (see comment) 789 84.55 186/220 nt 84.09 185/220 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [2.17.38.11] CARDLVGSIGSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); agcctctggattcacatttggtgactacgtcatgacttggatccgccaggGctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18010 JY8QFUQ01CX6UO productive Homsap IGHV3-48*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18011 JY8QFUQ01CZJAC unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F or Homsap IGHV3-74*01 F or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 117 80.56 29/36 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found cctctggattcacctctcctagatactggatgaatt +18012 JY8QFUQ01CZ1IL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*02 F 1 8 8 14 8.8.14 [1.17.38.11] CAKVGLMSARDRIDYW in-frame + ctctggattcacctttagcaactatgccatgagttgggtccgccaggctcaagggaaggggctggactgggtctcagatattagtaatagtggtggtgacacattctacgcaggctccgtgaagggccgcttcaccatctccagagacaattccaggaacactctatatctgcaaatggacagcctgagagccgaggacacggccgtgtattactgtgcgaaagtggggctgatgtccgctcgagaccgcattgactactggggccggggaaccctggtctccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18013 JY8QFUQ01AG9DV productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame - ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18014 JY8QFUQ01AE5OU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18015 JY8QFUQ01BG4L2 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + tctccggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +18016 JY8QFUQ01CDLHG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGVIAVAG#DFDCW out-of-frame + cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagggggttatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaantcaggcgccctgaccagcggc +18017 JY8QFUQ01CKL3J productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18018 JY8QFUQ01ADTQJ productive Homsap IGHV3-7*01 F 887 89.45 195/218 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18019 JY8QFUQ01BLJIG productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + gtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +18020 JY8QFUQ01BOAOM unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGG*GYRYGSVFLPA##W out-of-frame + stop codons ctctggattcacctttagtagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagtaattggtggtgatggtggtagtccatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaggggggtagggatacaggtatggttcggtattccttcccgcttgactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18021 JY8QFUQ01CVSYJ productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18022 JY8QFUQ01AL8VS productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 800 86.05 185/215 nt 85.58 184/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARADYYDTSAYYLDAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 60 of V-REGION: 9 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggggtacagcttgcgaggctctgttttgcactgggtccgccaggcttccgggaaaggactggagtgggttggccgtgtcggaaggcagggcgcgacaacatacgctgcgtcggtgaaaggcaggttcctcatctccagagatgatccagcgaacacggcttatctggaaatgaacagcctgaaaaccgaggacacggccgtctattactgtgctcgcgcagattactatgatactagtgcttattatctcgatgcttttgatatctggggccaggggacaattgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18023 JY8QFUQ01B7T0P productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +18024 JY8QFUQ01AVP58 No results +18025 JY8QFUQ01A6QQA productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattcaattttagttcttatggcatgaactgggtccgccaggctccagGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18026 JY8QFUQ01DCYQV No results +18027 JY8QFUQ01C3DIR No results +18028 JY8QFUQ01B75LI productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18029 JY8QFUQ01AI9PP productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 803 85.07 188/221 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-16*02 F 2 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLADDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtctctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggctgatgactactttgactactggggccagggaatctgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18030 JY8QFUQ01B2TLZ productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18031 JY8QFUQ01AV2PR unproductive (see comment) Homsap IGHV3-15*04 F 979 93.69 208/222 nt 93.24 207/222 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 2 8 10 X 8.10.X [1.16.38.11] CTHDAPYFLGER#FDYW out-of-frame + stop codons in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattccctttcagcaacacctacatgagctgggtccgccaggctccagggaaggggctggagtggttggccgtattgaaagcaaaactgatggtgggacaatagaatacgctgcacccgtgaaaggcagattaaccatatcaagagacgattcaaaaaacacgctgtatctgcatatgagcagcctgaagatcgaggacacagccgtgtattactgtacccacgatgccccgtactttttgggggagcgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +18032 JY8QFUQ01BBU4B No results +18033 JY8QFUQ01ARMZL No results +18034 JY8QFUQ01CIM0J productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 585 92.65 126/136 nt 91.91 125/136 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 X 16 8.X.16 [1.1.35.11] CVRYDYSRLHRSNYFGPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 81 nucleotides (from position 32 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcatcagttatggcatgaactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18035 JY8QFUQ01CX3GT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18036 JY8QFUQ01C0985 productive (see comment) Homsap IGHV4-4*07 F 1061 99.53 214/215 nt 98.14 211/215 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD4-11*01 ORF 2 8 7 13 8.7.13 [1.17.38.11] CARDFSNRGWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagtttctacCtggagctggatccggcagcccgGccgggaagggactggagtggattAgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18037 JY8QFUQ01BNJF8 unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGVVTA#LDYW out-of-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagnaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +18038 JY8QFUQ01BKSGU productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18039 JY8QFUQ01DGJPK productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + ctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18040 JY8QFUQ01BFC1J unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKSPLSVAGTRQNWFD#PG out-of-frame - ctctgacttgcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctgggggccagggaaccctggtcaccgtttcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18041 JY8QFUQ01ATQKU No results +18042 JY8QFUQ01CPNM5 unproductive Homsap IGHV3-30*01 F 909 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD6-6*01 F 3 8 8 X 8.8.X [1.17.38.11] CAREWAASHFDH## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 203 to 203 in the user submitted sequence), (cause frameshift); cgctggattcaccttcagtggctttgctttgcactggctccgccaggctccagacaaggggctagagtgggtgggatttacatcatttgatgggagtaacagagactacgcagactccgtgaagggccgattcacgatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagacctgacgacacgGgctgtatattactgtgcgagagagtgggcagccagtcactttgaccactggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18043 JY8QFUQ01BVL4F productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +18044 JY8QFUQ01BZ1MY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18045 JY8QFUQ01B3ID0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 923 91.74 200/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + cctctggattccccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaggggccgattcaccatctccagagacaacgccaggaactcattgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18046 JY8QFUQ01CAYJB unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +18047 JY8QFUQ01CGGE1 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 272 62.65 104/166 nt 8 10 X 8.10.X [1.17.20.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (10 AA in JY8QFUQ01CGGE1 ; 8 AA in Homsap_IGHV3-7*01), and low V-REGION identity (62,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcactttcactaacgcctggatgagctgggtccgccaggctccagggaaggggctggagtggattggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18048 JY8QFUQ01B09TL unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ2*01 F (see comment) 76 60.38 32/53 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18049 JY8QFUQ01ARLW2 unproductive Homsap IGHV3-72*01 F 1079 98.21 220/224 nt Homsap IGHJ6*04 F (see comment) 108 66.67 36/54 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYDP## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagggatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18050 JY8QFUQ01BT4IW No results +18051 JY8QFUQ01CRNO7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctagagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18052 JY8QFUQ01A56UP productive Homsap IGHV4-61*02 F 897 90.0 198/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + ctctggtggccccatcagcagtggtacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccacctacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgccgctgacacggccgtatattactgtgcgagagaacatagtaggacgatgggcggggcgagagagcttgactcctggggcctgggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +18053 JY8QFUQ01B1G7S productive (see comment) Homsap IGHV3-9*01 F 1040 97.71 213/218 nt 97.25 212/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CAKKSDINNIGWHGLFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcacctttggtaattatgccatgcactgggtccggcaagctccagggaGggggcctggagtgggtctcaggtattagttggaacagtggtagcatagactatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagctgaggacacggccttgtattactgtgcgaaaaaatcggatataaataacattggctggcacggcctatttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18054 JY8QFUQ01AC3PJ productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-59*08 F 993 96.26 206/214 nt 95.79 205/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAREDGSGRRHFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagtagttactactggagctggatccggcagcCccccaggaaagggactggagtggattgggtatatcttttacactgggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18055 JY8QFUQ01AF9LD productive (see comment) Homsap IGHV3-7*01 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); gctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaAagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18056 JY8QFUQ01C0IWS unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 826 87.79 187/213 nt 87.32 186/213 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.37.11] CAREKGSGPPTGMDV## out-of-frame + Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 187 in the user submitted sequence), (cause frameshift) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagcccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccacaggcatggacgtctgggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaactc +18057 JY8QFUQ01DGFIA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18058 JY8QFUQ01BIZKT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18059 JY8QFUQ01CY0IP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); cctctggattcacctacagcagcGtatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18060 JY8QFUQ01CI7HZ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAGHLLGDPFDYW in-frame - ggttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18061 JY8QFUQ01CTMBK No results +18062 JY8QFUQ01AZPY0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18063 JY8QFUQ01DMSZS unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDY## out-of-frame + tctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggcccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcacctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18064 JY8QFUQ01B5GC9 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 495 69.59 151/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] VHT#AFW out-of-frame + Low V-REGION identity (69,59% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgaggacaactttggtgaacacgccatgggatggatccgccagtctccgggggggattcttcagtgggtcgctgcgatcagtggtgacggactgacggcgtttcacgcagacttcgtggagggtcgattcagcatctccagagacaatcccataaacactctttttctgcaaatgaacagcctcagagtcgaagattcgggtgtctattttgtgcacacactgccttctggggccggggatcccgggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18065 JY8QFUQ01CT4VQ No results +18066 JY8QFUQ01DNI3E productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKIDSRNYDFWSGYYAHW in-frame - ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtttattactgcgcgaaaatagatagtcggaattacgatttttggagtggttattatgcacactggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18067 JY8QFUQ01A18TB unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 978 93.67 207/221 nt 93.21 206/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*02 F 2 8 8 X 8.8.X [2.17.38.11] CARGLAVFLE#FDYW out-of-frame - in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); cagcctctggattcaccttcagtagttatagcatgnactgggtccgccaggctccagggaagggactggagtgggtctcctCccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgttcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18068 JY8QFUQ01B6TBA No results +18069 JY8QFUQ01DGWLB No results +18070 JY8QFUQ01CAI91 productive (see comment) Homsap IGHV3-9*01 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); cctctggattcaattttagcaattatgccatgaactgggtccgccaggctccagggaagggcctggagtAgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18071 JY8QFUQ01CEBK2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVKDISRSGCFEYW in-frame + ctctggattccagtttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +18072 JY8QFUQ01DGYOH No results +18073 JY8QFUQ01CPJ2X productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 806 85.78 187/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18074 JY8QFUQ01CCKOI productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaGgaatttattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18075 JY8QFUQ01CQZEF productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18076 JY8QFUQ01DCDNV productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +18077 JY8QFUQ01C2EGT unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [0.17.38.11] CARDNYGDYW# out-of-frame - in CDR2-IMGT at codon 62 of V-REGION: 'CG' (2 nucleotides at position 90 to 91 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCGgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag +18078 JY8QFUQ01ARZ7N No results +18079 JY8QFUQ01BLVG5 unproductive Homsap IGHV4-4*07 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 3 8 7 X 8.7.X [1.17.38.11] CARQRGGGDRSG#FENW out-of-frame + in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 210 to 210 in the user submitted sequence), (cause frameshift); tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatTttttgtgcgagacaaagaggcggcggcgaccgcagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcaccctctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18080 JY8QFUQ01AHHL6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ccctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18081 JY8QFUQ01BZ3MR unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 688 80.09 173/216 nt 79.63 172/216 nt 7 8 X 7.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) ctctggatccagtttcagtggtttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18082 JY8QFUQ01AN30B No results +18083 JY8QFUQ01AQ4B3 unproductive Homsap IGHV3-33*05 F (see comment) 729 82.03 178/217 nt 81.57 177/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [2.16.38.11] CVKGRGYNDYGLDY## out-of-frame - Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) gcgtctggattctccttcagcaattatgccatccactgggtccgccaggctccagcaagggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactgggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18084 JY8QFUQ01ANPIM No results +18085 JY8QFUQ01AU2DJ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKKSIIIRGLI#YNFDYW out-of-frame + ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaagcattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18086 JY8QFUQ01AFPBP unproductive (see comment) Homsap IGHV3-74*03 F 869 88.99 194/218 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSDLGGQKGH## out-of-frame + stop codons cctcaggattcaccttcaggagttactggatgcactgggtccgccaagctccagggaaggggccgatgtgagtcgcacgtcttaatgaagatggcagctacacaacttacgcggactccgtgaagggccgattcaccatctccagagacaacgccgagaacaagctctatttgcaaatgagcagtctgagagttgaggacacggctgtctattactgtgtaagcgatttgggtggtcagaaaggtcactggggccagggagcccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttccccgctgagcctcgacagcaccccccctaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18087 JY8QFUQ01CMNOI productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18088 JY8QFUQ01CBP29 productive Homsap IGHV1-2*02 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDWGGTYAPLDNW in-frame - tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaaccttgaccagtgacacgtccatcagtacagcctacatggaaatgagcgggctgacgtctgaggacacggccatcttttactgtgcgagagattggggtggcacgtacgctccgcttgacaattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18089 JY8QFUQ01DDFKI No results +18090 JY8QFUQ01BUUXL productive Homsap IGHV3-30-3*01 F, or Homsap IGHV3-30-3*02 F (see comment) 407 79.39 104/131 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 X 5 18 X.5.18 [X.X.38.11] CARDDFYSSGNYGGFGMDVW in-frame - Low V-REGION identity (79,39% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaccttcagtcactatgactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18091 JY8QFUQ01CPY4L No results +18092 JY8QFUQ01AKIZN productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 776 83.71 185/221 nt 83.26 184/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFETW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'TG' (2 nucleotides at position 37 to 38 in the user submitted sequence), (cause frameshift); tttccggtagttccatcagtagcagtgattactactTGggggctgggtccgccagtccccagggaagggtctggagtggattggaagtgtctattacagggggacgcagtacctcaacccgtccctccagagtcgagtttccatttccattggcacgtccaagacgcaattctccctgagactgaggtctgtgaccgccgcagacacggctatgtattactgtgcgagacatcggtcttttggagtgataattgtgaattactttgagacctggggacagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18093 JY8QFUQ01APXOI No results +18094 JY8QFUQ01BBX78 productive (see comment) Homsap IGHV3-30*04 F, or Homsap IGHV3-30*07 F or Homsap IGHV3-30*15 F or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*02 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*06 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 8 13 8.8.13 [1.17.38.11] CATYGRFSFSPLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cttctggattcacctctggtgattatgctatgagctggctccgccaggctccagggaaggGggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctccccttgactactggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +18095 JY8QFUQ01C411I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [2.17.38.11] CARDRLTISALDYW in-frame - aggcctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18096 JY8QFUQ01B68DP productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 953 93.95 202/215 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD2-8*02 F 3 8 7 14 8.7.14 [1.17.38.11] CARGRCGLVGCWFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctatggtgggtccttcagtggttactactggagctggatccgccagtccccagggaaggggctggagtggatcggggaaatcaatcataatggatccaccagctacaacccgtccctcaagggtcgagtcaccatatcagtagacacgtccaagaaccagttctccctaaagctgagttctgtgaccgtcgcggacacggctgaatatttctgtgcgagaggtcgctgcgggcttgtggggtgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18097 JY8QFUQ01BGRWQ unproductive Homsap IGHV3-30*01 F 991 94.98 208/219 nt Homsap IGHJ4*02 F (see comment) 78 62.5 30/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [2.17.38.11] CSNGYGDFPRRW# out-of-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctagattcaccttcagtagctataatatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgttcgaatggttacggtgacttcccgcgtaggtgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +18098 JY8QFUQ01A0ZW5 productive Homsap IGHV4-61*02 F 857 87.78 194/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 11 10.7.11 [1.17.38.11] CARSGWDNQFDFW in-frame + tctctggtgtcgccaccagtagtggcacttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaacccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18099 JY8QFUQ01CAQER unproductive Homsap IGHV3-7*01 F 1058 98.62 215/218 nt 97.71 213/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CARSLVGADVFDY## out-of-frame + in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtagctattggatgagctgggtccgccaggctccaggGgaaggggctggagtGgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgactcaccatctccagagacaatgccaagaagtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggtcgttagtgggagctgacgtatttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt +18100 JY8QFUQ01B1X6H productive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*11 F or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 795 85.51 183/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [0.17.38.11] CVRVRDYEIGGDFW in-frame + tggaggcgccttcagcacctttcatatcacctgggtgcgacaggcccctggacaagggcttgtctggctggggaatatcattcctatttttggaacagtcgactacgcacgggggttccagggcagagtcacgattaccgcggacgaatccaccaacacagcctacatggagttgagcagcctgacatctgaggactcagccgtctatttctgcgtgagagttcgtgactatgaaattggtggtgacttctggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaac +18101 JY8QFUQ01CU723 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 266 67.72 86/127 nt 8 8 X 8.8.X [1.17.8.X] null + No rearrangement found Low V-REGION identity (67,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18102 JY8QFUQ01BPS3D productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame + ctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +18103 JY8QFUQ01CQG5W No results +18104 JY8QFUQ01CPM0Z unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 935 93.02 200/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARDCDSGECNFDYW in-frame - stop codons tctgattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18105 JY8QFUQ01C3ODE No results +18106 JY8QFUQ01B40ET unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKKTL*FGDLF#YNFDYW out-of-frame - stop codons in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggagggggActggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaacattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18107 JY8QFUQ01AIEID productive (see comment) Homsap IGHV4-39*07 F 874 89.04 195/219 nt 88.58 194/219 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 10 6 10 10.6.10 [1.17.38.11] CASHGGKYFPQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagcccccagggaaggggctggagtggattggacaaatccatcatgtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttct +18108 JY8QFUQ01B1E0Q unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 723 80.72 180/223 nt Homsap IGHJ3*01 F (see comment) 133 74.0 37/50 nt Homsap IGHD3-9*01 F 3 8 10 X 8.10.X [1.17.38.11] CATDSPTGYYAF##VW out-of-frame + Low V-REGION identity (80,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) ttctggattcacttttagcagtcatatgatgagttgggtccgccaggctccagggaagggactggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgcatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18109 JY8QFUQ01AI3J7 unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 98 of V-REGION: 'G' (1 nucleotides at position 198 to 198 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 99 of V-REGION: 'G' (1 nucleotides at position 204 to 204 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgagGgacacGggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18110 JY8QFUQ01BXZ1R productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtacatactggatgcactgggtccgccCaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +18111 JY8QFUQ01CKQGV productive Homsap IGHV1-8*01 F 963 96.15 200/208 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-15*01 F 2 6 8 21 6.8.21 [X.17.38.11] CARRVGRWLRGDPRRLYYGMDVW in-frame - caccttcagcagtgatgatatcaactgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaacagtggaaacacaggctatgcacagaagttccagggcagagtcagcatgaccaggaacacctccataagcacagcctacatggacctgagcaacctgagatctgaggacacggccatatattactgtgcgagaagagttggaaggtggcttcggggagacccgcgacggctctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18112 JY8QFUQ01A4YPX unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDNYGDYW# out-of-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +18113 JY8QFUQ01BERAB unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18114 JY8QFUQ01CQSW9 productive Homsap IGHV4-61*02 F 902 90.05 199/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 14 10.7.14 [1.17.38.11] CAREKVVIRPNWFDPW in-frame + tctctggtgactccatcaccagtggtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaatccctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagagaaaaagtagtgatccgtcccaactggttcgacccctggggccagggagccctggtcatcgtctcctcagcctccaccaaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18115 JY8QFUQ01DLDNS productive Homsap IGHV4-4*07 F 840 87.91 189/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 7 9 8.7.9 [1.17.38.11] CARDSGDFDYW in-frame - tctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtccaaaccagtgggaccccccactacaacccttccctnaagagtcgagtcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccatttttttctgtgcgagagactccggggactttgactactggggcccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18116 JY8QFUQ01BTOS2 productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 7 10 8.7.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); cctctggattcaccgtcaGgtaacaactacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggtgacacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatcccgaccagcccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +18117 JY8QFUQ01BE0SM unknown (see comment) Homsap IGHV3-19*01 P, or Homsap IGHV3-48*01 F 129 51.79 101/195 nt 8 8 X 8.8.X [1.17.30.X] null + No rearrangement found ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggaaccctggtcaccgtctccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18118 JY8QFUQ01DQLNG unproductive (see comment) Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ1*01 F (see comment) 116 69.23 36/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARWRGQQSE*Y# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaatgatactgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18119 JY8QFUQ01BL7KX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 778 84.72 183/216 nt 83.8 181/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [1.16.38.11] CTKTRVVLGITFPFYIYGLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggattcacgttcgacaactatgccatgagctgggtccgccaggcaccaggaaagggctggagtgggtctccagtattagtggtaatggagaaattgtacaccacgcagacgccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtTttttgcaaatgaatggagtgagagacgacgacacggccatttactactgtacgaaaacacgcgttgtgttgggaattacatttccgttctatatctatggtctggacgtctggggccaagggaccacggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18120 JY8QFUQ01CULLC productive Homsap IGHV3-7*01 F 919 91.32 200/219 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [2.17.38.11] CSRLLEEW in-frame - cctctggttttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccaaccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18121 JY8QFUQ01BTHCZ unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1019 95.93 212/221 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 1 10 7 X 10.7.X [1.17.38.11] CAWGGSG*#YFDYW out-of-frame + stop codons tctctggtggctccatcagcagtactagttactactggggctggatccgccagcccccagggaaggggctggagtggattggtaacattcattctagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcatggggtggttcgggttgaactactttgactactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18122 JY8QFUQ01BCXG9 No results +18123 JY8QFUQ01AYT0Y unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found agttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +18124 JY8QFUQ01CNLFV No results +18125 JY8QFUQ01AF7AJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18126 JY8QFUQ01B1UP0 productive (see comment) Homsap IGHV4-4*07 F (see comment) 746 83.26 179/215 nt 81.86 176/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 3 9 7 16 9.7.16 [1.17.38.11] CARERSISIGGAREFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 37 of V-REGION: 'ATA' (3 nucleotides at position 29 to 31 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); tcactggtggccccatgggcagtagtttATActtctggaattgggtccgacaGgcccgccgggaagagactggagtggatcggAcgtggtttatgatgatgggagtacccgctacaatccctccctcaggggtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaggttgagttttgtgaccgccgcagacacggcccgttattactgtgcgagagaacggagtatttcgattggcggagcgagagaatttgactcttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18127 JY8QFUQ01CVHKX productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 840 88.32 189/214 nt 87.85 188/214 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVSDLAGQKGSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'TG' (2 nucleotides at position 50 to 51 in the user submitted sequence), (cause frameshift); aggattcaccttcagtaggtactggatgcactgggtccgccaagttccaTGggaaggggaccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +18128 JY8QFUQ01CEYYX productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'C' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtacatactggatgcactgggtccgCccaagctccagggaaggGggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18129 JY8QFUQ01BYBVC unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt 99.53 214/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttactactggagctggatccggcagcCccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18130 JY8QFUQ01BV99D productive (see comment) Homsap IGHV3-64*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaTttttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18131 JY8QFUQ01AFHQC productive (see comment) Homsap IGHV4-34*03 F 885 90.61 193/213 nt 90.14 192/213 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD3-22*01 F 3 8 7 16 8.7.16 [1.16.38.11] CVRNYMILVVISIGSTPG in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tgtctggtgggtccttcagtggttactactggagttggatccgccagccccagggaaggggctggagtggattggggaaatcaattatagaggaagtaccaactacaatccgtccctcaaaagtcgagtcaccgtgtcttcagacacgtccaagaatcagttctccctggagttgatctctgtgaccgccgcggacacggccatatattattgtgtgagaaattatatgattttagtggttatttcaattggttcgactcctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18132 JY8QFUQ01C6GTE productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggctcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18133 JY8QFUQ01DK33J unknown (see comment) Homsap IGHV4-39*02 F 946 92.69 203/219 nt 91.32 200/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.16.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 52 of V-REGION: 2 nucleotides (from position 77 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagcagtGagtagttactactggggctggatccgccagtccccagggaaGggggctggagtgattggaatatctattatcgtgggagcacctattacaacccatccctcgagagtcggctcaccatgtcggtagacacgtccaggaacctcttctccctgaggctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagcgtgactacggtgtctatgaggatgaaatactgggggccgggggaacccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18134 JY8QFUQ01ASFLD unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ6*01 F (see comment) 99 61.9 39/63 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDRELHYQHLDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 177 to 177 in the user submitted sequence), (cause frameshift); cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaAatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctgggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18135 JY8QFUQ01AVDHQ productive Homsap IGHV3-9*01 F 945 93.09 202/217 nt Homsap IGHJ1*01 F (see comment) 143 75.0 39/52 nt Homsap IGHD4-17*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARLPGDYGSRW in-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaactttgataaatatgacatgcactgggtccgacaagctccagggaagggcctggagtgggtctcaggtattaagtggaatggcggtcgcgtcggctatgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagacctgaggacacggccttctattactgtgcaagactccccggtgactacgggtctcgttggggccagggaaccctcatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +18136 JY8QFUQ01BSRSP productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD4-11*01 ORF 2 8 7 17 8.7.17 [1.17.38.11] CARVGRSVGYSDSGWFDPW in-frame + ctctggtggctccatgagtagttactactggaactggattcggcagcccccagggaagggactggagtggattgggtatatctattacactgggatcaccaactacaatccctccctcaagagtcgagtcaccatgtcaatagacacgtccaggaagcagttctccctgaccctgacctctgtgaccgctgcggacacggccgtctatttctgtgcgagagtcggccggagtgtgggctacagtgactctgggtggttcgacccctggggccagggaaccctggtcaccgtctcctaccatccccgaccagccccaaggtcttccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18137 JY8QFUQ01CA3DQ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1040 97.71 213/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaagccctggctnaccgtctcctcagcatcccccgaccagcccccaaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +18138 JY8QFUQ01CERC2 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 858 89.25 191/214 nt 88.79 190/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 2 8 7 19 8.7.19 [1.17.37.11] CARSSDYLWGSYRYPYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 83 of V-REGION: 1 nucleotides (from position 150 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagttacttctggagttggatccggcagcccccagggaagggactggagtggattggatatgtctattacagtggaagtaccaagtataatccttccctcgaaagtcgagtcaccatatcattagacacgccaacaaccagttctccctgagcctgacctatgtcaccgctgcggacacggccatatactactgtgcgagaagctctgattacctttgggggagttatcgttatccctactacttcgactactggagccagggaaccctggtcaccgtctccttagcatccccgactagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18139 JY8QFUQ01CBF2O unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt +18140 JY8QFUQ01BUAS2 productive Homsap IGHV3-48*02 F 891 90.32 196/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [1.17.38.11] CARGQKWLQVLRWFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18141 JY8QFUQ01AKD9K productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagnacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +18142 JY8QFUQ01A3P8I productive Homsap IGHV3-30*19 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-8*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARNELPWGTIESYFDYW in-frame + cgtctggattcaccttcagaacctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcacttatatcatatgatggaagtaatatatactactcagactccgtgaagggccgattcaccatctccagagacaattccaaggacacgctgtatctgcaaatgaacagcctgagagctgaggacgcggctgtatattactgtgcgagaaatgagctgccttggggtacgatagagtcctactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18143 JY8QFUQ01AP263 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKENYFESSGYHGMNVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcacctttaccaactatgccatgacctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtaatcgtggtactggagtgtactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagagccgaggacacggccctttattactgtgcgaaagagaattactttgagagtagtggttatcacggtatgaacgtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18144 JY8QFUQ01DJGLE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18145 JY8QFUQ01A2XEM productive (see comment) Homsap IGHV4-61*02 F 887 89.5 196/219 nt 87.67 192/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.16.37.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 72 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 81 of V-REGION: 1 nucleotides (from position 151 in the user submitted sequence), (cause frameshift) tctccggtggctccatcagtactggttattactactggGagctggatccggcagtccnccgggaagggactgaatggattgggcgcatgtctgccagagggggAcagcaactacaacccctccctccagagtcgagtcaccatatccatagaacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18146 JY8QFUQ01DKDCG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18147 JY8QFUQ01BRZ0F No results +18148 JY8QFUQ01CFTFO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDGVRGVGAYYIYYFDLW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccagactccagggaaggggctggagtggctcgcaactattagtggtagtggaagtagatcattttacgcagactccctgaagggccggttcaccatctccagagacaattccaagggcacggtatacctggaaatgaccaccctgagagccgaggacacggccgtatattactgtgcgagagatggggtccgtggcgttggtgcttactacatctactattttgacttatggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt +18149 JY8QFUQ01ALJS1 productive Homsap IGHV3-21*04 F, or Homsap IGHV3-23*01 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18150 JY8QFUQ01C7FFT No results +18151 JY8QFUQ01CTX39 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt 94.01 204/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtCagtgactggatgtactgggtccgccaagctccagggaaggGggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18152 JY8QFUQ01CADD3 No results +18153 JY8QFUQ01CEYH3 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 592 91.49 129/141 nt 90.78 128/141 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 3 8 X 13 8.X.13 [1.2.35.11] CARGRYGDQVTWDYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 41 of V-REGION: 76 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctataccttgagttggatgcagtgaagggccgattcaccatttccagagacaacgccaagaactccctctctctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagaggtcgctacggtgaccaagtaacctgggactactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +18154 JY8QFUQ01BW65G No results +18155 JY8QFUQ01CRQ67 No results +18156 JY8QFUQ01CCN00 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 955 93.15 204/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 13 8.8.13 [2.17.38.11] CARGGGGKSIPLDNW in-frame - gcgtctggcttcacgttcagtagttatggcatgcaatgggtccgccaggctccaggcaaggggctggagtgggtggcagttatttggtatgatggaagtaataaatattatgcagactccgtgaagggccgattcgacatctccagagacaattccaagaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatgtaccattgtgcgagaggcggcggtggtaagtccattccacttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18157 JY8QFUQ01BP9B9 No results +18158 JY8QFUQ01DEBXU productive Homsap IGHV3-11*04 F, or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F 977 92.51 210/227 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [4.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggctgacggtgtcgtggaactc +18159 JY8QFUQ01BM1BK No results +18160 JY8QFUQ01AWCIW unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 640 85.55 148/173 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgc +18161 JY8QFUQ01AECK2 No results +18162 JY8QFUQ01CHTU1 unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 933 93.84 198/211 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 3 8 7 X 8.7.X [0.17.38.11] CARGDGLR#DYW out-of-frame + tggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacgggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18163 JY8QFUQ01AIYO5 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARVRGYYGGQYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccancccctcaaggtttcccgctgagcctctgccagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +18164 JY8QFUQ01DREX7 No results +18165 JY8QFUQ01CN0EQ No results +18166 JY8QFUQ01BPWU6 productive (see comment) Homsap IGHV4-39*02 F 915 90.91 200/220 nt 89.55 197/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 3 9 7 14 9.7.14 [1.17.38.11] CARPGARETNNAWVDW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 32 in the user submitted sequence), (cause frameshift) tctctggtgGgctccgtcagtaggagtccctatactggggctGggatccgccagcccccagggaaggggctggagtggattgggaccatctattatagtgggaccacatactccaatccgtccctcaagactcgagtcaccatgtccttggacacgtccaagaaccacatctccctgaagctgaattctgtgaccgccgcagacacggctgtttattactgtgcgagacctggggctagggagactaataacgcctgggtcgactggggccagggcaccctggtcaccgtctcctcggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18167 JY8QFUQ01CZEZJ productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 820 86.3 189/219 nt 85.84 188/219 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [2.17.38.11] CVRDLNWSFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); gcctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatGacaaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18168 JY8QFUQ01CGQAI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame - ctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18169 JY8QFUQ01C4JSD productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc +18170 JY8QFUQ01CL36G productive (see comment) Homsap IGHV3-48*01 F 955 93.15 204/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDGGLYGTLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); acctctggattGcacctttagtaaccatTgggatgaactgggtccgccaggctccggggaaggggctggaatgggttgcatacattagtagtgatggtagtaccctatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaaagactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagacgggggactctacggtactcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18171 JY8QFUQ01BS7GX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 870 88.64 195/220 nt 88.18 194/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CTKVASQVIMATTYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); agcctctgaattcacttttagtacctatgtcataagttgggtccgccaggtcccagggaAaggggctggagtgggtctcaagtattgttgatggtggtgatatcacacactacgcagactccgtgaagggccggttcaccatctccagagacgaatccaagaacactgtctatctgcaaatgaacagcctgagagccgaggacacggccgtgtactactgtacgaaggtggcgagtcaagtgatcatggctacaacctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18172 JY8QFUQ01AE11Y No results +18173 JY8QFUQ01B6450 productive Homsap IGHV3-7*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + cctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactcttcccccgaaccgggtgacggtgtcgtggaacctcagg +18174 JY8QFUQ01CAT3O unproductive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD1-1*01 F 1 8 7 X 8.7.X [1.17.38.11] CARGSSKAYNWFD#PG out-of-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaactc +18175 JY8QFUQ01CH4GT productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1055 100.0 212/212 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [0.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18176 JY8QFUQ01BMV5F unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDASRYYYNSYCDN## out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccGaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctattcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18177 JY8QFUQ01B6DQJ productive Homsap IGHV3-48*01 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18178 JY8QFUQ01DR7OC unproductive Homsap IGHV3-48*02 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRGYSNGLRYYAMDV## out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 63 of V-REGION: 'T' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); cctctggattcggcttcagtgactatggcatgaactgggtccgacaggctccagggaagggtctggagtgggttgcctatcttagtagtagtagttTttatcatatattatggagactctgtgaagggccgattcaccatctccagggacaatgccaacaactcactgtatctacaaatggacagcctgagagacggcgacacggctgtttattactgtgcgagagatcgtggatacagcaatggacttcgctactatgccatggacgtctggggcccaagggacaacggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18179 JY8QFUQ01DJKRD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcacctttggttattatggcatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18180 JY8QFUQ01CFTZX productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18181 JY8QFUQ01CW6SR productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18182 JY8QFUQ01A4RGQ productive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD7-27*01 F 1 8 10 10 8.10.10 [1.17.38.11] CVRDPFSSRGHW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcatcctcagtgactaccacatggagtgggtccgccaggctccagggaaggggctggagtgggttggccgtagtagaaagaaagctaatagttacagtacagaatatgccgcgtctgtgaaaggcagattctccatttcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaatcgacgacacggccgtgtattattgtgtcagagaccccttctcaagtcggggccactggggccagggaaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18183 JY8QFUQ01CMRMI productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGGEDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggGggctggagtgggtctcacgtattaatgaagatgggaggactacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacaccaagaacacactgtatctgcagatggacagtctgagagccgaggacacggctgtgtattactgttcaaaagacacctttgggggagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacggggtcgtcgcatgcctggtccagggcttcttccccca +18184 JY8QFUQ01AI52U productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 868 89.35 193/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame - tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtttcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18185 JY8QFUQ01CRA60 productive (see comment) Homsap IGHV3-7*01 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [2.17.38.11] CARSGSGSHLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); gtctctggattcacctTttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18186 JY8QFUQ01BWE6J productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18187 JY8QFUQ01CECS2 No results +18188 JY8QFUQ01DJ7Q8 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 828 87.1 189/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGFSAWGQDAFDI## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttgggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18189 JY8QFUQ01A202Z No results +18190 JY8QFUQ01C0FW1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1053 98.62 214/217 nt 97.7 212/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*03 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'TC' (2 nucleotides at position 10 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); ctctggattTCaccgtttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcGtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18191 JY8QFUQ01A4A0G No results +18192 JY8QFUQ01B8CJH No results +18193 JY8QFUQ01A3W9F productive Homsap IGHV4-4*07 F 877 89.81 194/216 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 7 12 8.7.12 [2.17.38.11] CARFSSYGDTFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gtctctgatgggtccatcggaagttactactggacttggatccggcagcccgccgggaaggcaatggagtggatcgggcgtgtctttagaactgggaacacgaattacaacccctccctcaagagtcgggtcaccatgtcagttgacacgtccaagaatcaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgttttactgtgcgagattctcgtcctacggtgacacctttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +18194 JY8QFUQ01BUNR5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD2-8*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKGASTAVMVSGTDCYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattccccttcagcacctatcccatgagctgggtccgccaggctccagggaggggactggagtgggtcgcaactataagtggtggaggttatagtatatatgacgcagactccgtgaagggcaggttcaccatctccagagacaactccaagaccaccttgtttctggaaatgaaaagtctgagagtcgatgatacggccgtctattactgtgcgaaaggggcctcgactgcagtaatggtgtctggaacagattgttacggtttggacgtctggggccacgggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18195 JY8QFUQ01BUB3X productive Homsap IGHV3-7*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + tctctagattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcc +18196 JY8QFUQ01BCH3I No results +18197 JY8QFUQ01CCC1O productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 172 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGXYSDYW in-frame + gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcgggganttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18198 JY8QFUQ01CNJM1 unproductive (see comment) Homsap IGHV4-61*02 F (see comment) 920 90.95 201/221 nt Homsap IGHJ6*02 F (see comment) 89 59.68 37/62 nt 10 7 18 10.7.18 [1.17.38.11] IVRRGKWGDKPPFYYGMDVW (see Functionality comment) in-frame + stop codons, IMGT/JunctionAnalysis gives no results for this JUNCTION Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctgattgattgtncgacgagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaaggaccacggtcaccgtntcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18199 JY8QFUQ01DBEYG unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*03 F 728 87.7 164/187 nt 8 8 X 8.8.X [1.17.28.X] null + No rearrangement found ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctg +18200 JY8QFUQ01CU30A unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +18201 JY8QFUQ01CBMWP No results +18202 JY8QFUQ01BYAI8 productive (see comment) Homsap IGHV3-9*02 F 910 90.87 199/219 nt 90.41 198/219 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [2.17.38.11] CGKDMRPGGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); gcctccggattcacctctgGaaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +18203 JY8QFUQ01DGNP4 productive (see comment) Homsap IGHV3-49*04 F 970 93.24 207/222 nt 92.34 205/222 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 10 17 8.10.17 [2.16.38.11] CTRDNPPLRSLEWLPFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 57 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) ggctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccaggaagggctggagtggtcggtttcattagaagcaaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18204 JY8QFUQ01BWU5P productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 803 85.07 188/221 nt 84.62 187/221 nt Homsap IGHJ3*01 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-16*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARTYTYRNAFDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 36 of V-REGION: 'CAGT' (4 nucleotides at position 29 to 32 in the user submitted sequence), (cause frameshift); tctttggtgactctctgagtaccagtagCAGTtttctactggggctgggtccgccaggccccagggaagggactggagtgggttgggactgtttattatagtgggagcgcccactacaatccgtccctcaagagtcgagtcgccatatccgtggacacggcccaaaaccaggtctccctgactttgaactctgtgaccgccgcagacgccgctgtctatttctgtgcgagaacttatacttatagaaatgcttttgacgtctggggccaggggacattggtcgctgtgtcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +18205 JY8QFUQ01CANLM productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 998 96.28 207/215 nt 95.81 206/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18206 JY8QFUQ01CDZ5R productive (see comment) Homsap IGHV3-30*01 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*01 F 97 66.0 33/50 nt Homsap IGHD2-2*02 F 2 8 7 11 8.7.11 [1.17.38.11] CACGHMRDGYDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggcccaagggacaaaggtcaccgctcttcatcatgcccgatcccgacccaaggtccagttcctgccgtctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18207 JY8QFUQ01DBU74 unproductive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt 82.49 179/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CVKGRGYNDYGLDY## out-of-frame - Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatAttaatgaaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactgggggcccgggaaccctgctcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18208 JY8QFUQ01B728J productive (see comment) Homsap IGHV3-7*01 F 904 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctggattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +18209 JY8QFUQ01A901C productive Homsap IGHV3-11*01 F 833 87.16 190/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CVREVTGVWDWFDPW in-frame - cctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18210 JY8QFUQ01CJ3NN productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*02 F 1 8 8 10 8.8.10 [1.17.38.11] CAREFWWRLDFW in-frame - cctctggattcacctttagtggccattatatgacctgggtccgtcaggctccagggaaggggctggagtgcgtggccaagataaagccagatggaagtgaggaattctatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctgcaattgaacaccctgagagtcgaggacacggctatttatcactgtgcgagagagttctggtggcggcttgacttctggggccagggagccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggaggcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18211 JY8QFUQ01DLIX0 No results +18212 JY8QFUQ01CWPJP productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 866 88.24 195/221 nt 87.33 193/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARQLSGDYASFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'G' (1 nucleotides at position 169 to 169 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaccagtggtactttttactgggcctggatccgccagcccccagggaAaggggctggagtgggttggcaatatctattctagtggtgtcgcctattacaacccgtccctcaagagtcgagtcaccatgtccgtcgacacgtccaagaatgagGttttccctgacactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18213 JY8QFUQ01CG6XI productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARDRRPLREFDCW in-frame + cctctggattcaccctctccagctatgctatgcactgggtccgccagtctcccggcaaggggctagagtgggtggcagctatttcatatgatggaagtaaaatatattacgcagactccgtgaggggccgcttctccatctccagagacagttccaagaacactctgcatttgcaaatggacagcctgagacctgaggacacggctacatattactgtgcgagagatagacggccacttagggagtttgactgttggggccagggaaccccggtcgccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggggcttcttccccca +18214 JY8QFUQ01AF1EK unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactGggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18215 JY8QFUQ01A5V24 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaccc +18216 JY8QFUQ01B5L4G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18217 JY8QFUQ01B09U4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKIDSRNYDFWSGYYAHW in-frame - cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtttattactgcgcgaaaatagatagtcggaattacgatttttggagtggttattatgcacactggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18218 JY8QFUQ01AFUZV productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18219 JY8QFUQ01CHKE9 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame - tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18220 JY8QFUQ01BNAXM productive (see comment) Homsap IGHV4-4*01 F, or Homsap IGHV4-4*02 F or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 2 9 7 14 9.7.14 [1.17.38.11] CARDKDVTARGTFDMW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagtaattactGggtggatttgggtccgccagtccccaggggaggggctggagtggattggagaagtctatcatactgggaccacctattacaacccgtccctgaagagtcgagtcaccctgtcagtagacaagtccaggaatcagttctccctggagatgacttctgtgaccgccgcggacacggccgtgtatttctgtgcgagagataaagacgtgacagctcgtgggacctttgatatgtggggccaggggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +18221 JY8QFUQ01CLRF1 No results +18222 JY8QFUQ01CO5ED productive Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 761 83.49 182/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARDPGFSAFDYW in-frame - Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaacttcagagattattggatgagctgggtccgccagactccggggaaggggctggagttcgtggccaacataaataaagatggaagtgtgaggaactatgtcgactctataaaggggcgatccagcatttccagagacaacgcccagaatttaatgtttctgcagatgaacggcctgagggccggcgacacggcaatatattactgtgcgagagaccccggcttttccgcttttgactactggggccagggaatcctggtcaccgtctccccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18223 JY8QFUQ01AVOIO productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 805 85.71 186/217 nt 84.79 184/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 7 8 9 7.8.9 [2.16.38.11] CTGLTYPDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) acgtctggatttaccttcagtaagttctgatgcattgggtccgccaagctccagggaagggctgacttgggtctcacgnattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18224 JY8QFUQ01ABGCX productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 959 93.58 204/218 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARLPNTIDSW in-frame + Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) cttctggatatagttttgccacctactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatgggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatttcagccgacaagtccctcagtatcgcctacctgcagtggagcagcctgcaggcctcggacaccgccatatattactgtgcgagactgcctaacactattgactcctggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18225 JY8QFUQ01AI46E productive (see comment) Homsap IGHV3-30*07 F 1000 95.43 209/219 nt 94.98 208/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.17.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18226 JY8QFUQ01BSQQU No results +18227 JY8QFUQ01AH4LA productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - tctggagttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18228 JY8QFUQ01BNDD3 productive Homsap IGHV3-7*03 F 846 88.02 191/217 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcatttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccccaagatgggaacgtggtcgtcgcatgcctggtccccaaggcttcttccccc +18229 JY8QFUQ01CV6WG productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.38.11] CARGRTVVTVIDYIDYW in-frame - ctctggggactccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18230 JY8QFUQ01BY9OT unproductive Homsap IGHV3-7*01 F 928 91.78 201/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [2.17.38.11] CAISSGFTRR#YW out-of-frame - ggctctggagttcagcttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18231 JY8QFUQ01CIXN5 productive Homsap IGHV3-30*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDELPWDTIEYYFDYW in-frame + ctctggattcaccttcaatacctattctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18232 JY8QFUQ01AW4QC unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 783 92.78 167/180 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattga +18233 JY8QFUQ01DDZ72 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18234 JY8QFUQ01CPT27 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18235 JY8QFUQ01CBRTT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CILLYYDSRGVFSTDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggcgtgggtctcacgtattaaaagtgatggcagtggcacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagagcacgctgtttctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtatactgctttactatgatagtagaggtgtcttttcaaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18236 JY8QFUQ01CGHQC productive Homsap IGHV3-48*01 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18237 JY8QFUQ01CM97Q No results +18238 JY8QFUQ01C0EZ2 productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - tctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcgtgcttctacccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18239 JY8QFUQ01BD9E4 No results +18240 JY8QFUQ01B9NGM productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 984 93.72 209/223 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 2 8 10 16 8.10.16 [1.17.38.11] CAADGCPGGTCYHGFDMW in-frame - ctctggattcactttcagtaacgtctggatgcactgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgctggtggggcaacagaatacgctgcgcccgtgagaggcatattctccatctcaagagatgattcaaagaacacgttgtatctgcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtgccgcagatggttgtcctggtggtacctgctatcatggttttgatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18241 JY8QFUQ01DIDUE productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18242 JY8QFUQ01BLFUH productive Homsap IGHV4-39*02 F 834 86.82 191/220 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18243 JY8QFUQ01AQN4P productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARPGVGASSFIDFW in-frame - ttctggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18244 JY8QFUQ01AXASL productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 907 92.02 196/213 nt 91.55 195/213 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 7 12 8.7.12 [0.17.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) tggattcagcttcagtacctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtactaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattattgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18245 JY8QFUQ01DFEC5 unproductive (see comment) Homsap IGHV3-30*01 F 846 88.02 191/217 nt 86.64 188/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CVGGQ*PAPGG#FNYW out-of-frame - stop codons in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 205 to 205 in the user submitted sequence), (cause frameshift); ctctggattcaacttcaatggctttaatatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagAttttgtcatatgatggaaAataataagttctacgcagactccgtgagtggccgattcaccatctccacagacagttccaagaggacattgtttctgcaaatgaacaacctgacaactgaagacacgGgctctttattactgtgtggggggacagtagccggccccggggggccttttaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18246 JY8QFUQ01CCQ82 productive Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARPAGEGDPFFHYYSGLDVW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18247 JY8QFUQ01BBXFA No results +18248 JY8QFUQ01C39NJ No results +18249 JY8QFUQ01AIHLU productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 810 86.18 187/217 nt 85.25 185/217 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSGSSEYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctgggattcaGcgttaagttcttatggcatgaactGgggtccgccaggctccatggggggggctggagtgggtctcattcattaacagtattagtagttataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18250 JY8QFUQ01CA4R1 productive (see comment) Homsap IGHV3-7*01 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 8 14 7.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) cctctggatttacttttacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaaaCgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18251 JY8QFUQ01APB0H productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18252 JY8QFUQ01BTVIS unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 563 72.94 159/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (72,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctagattcatctttagtagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactatcagtggtagtggtgataacacatactacgcagactccgtgaagggccggttcaccatctccagagacaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +18253 JY8QFUQ01AFI4A No results +18254 JY8QFUQ01AZXKI unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18255 JY8QFUQ01CU8RS productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18256 JY8QFUQ01BVVHP productive (see comment) Homsap IGHV3-7*01 F 1000 95.43 209/219 nt 94.98 208/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CVRGRDGVNFGEMDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagcagacattggatgacctgggtccgccaggctccagggaagaggctggagtgggtggccaacatGaaaacaagatggaagtcagagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgtgaggggtagagatggtgttaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18257 JY8QFUQ01BCL4K productive Homsap IGHV3-48*04 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.17.38.11] CAKKSDINNIGWHGLFDYW in-frame - gcctctggattcgccttcagtagttccagcatgaactgggtccgccagggtccagggaaggggctggagtggatttcacacattaggggtagtagtagtaccacccactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagctgaggacacggccttgtattactgtgcgaaaaaatcggatataaataacattggctggcacggcctatttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18258 JY8QFUQ01BEUMV No results +18259 JY8QFUQ01A3QNJ productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 823 87.04 188/216 nt 85.65 185/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); gtctctggggactccattagtggttactattggacgtggatccggcagAgccccagggaagggactggagtggattggaaatgtccattacacCtgggagtaCccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18260 JY8QFUQ01ACFX8 productive Homsap IGHV3-30*10 F 927 92.17 200/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD3-9*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARDRDFDFPAYGLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacttcagtaactatgctgtgcactgggtccgccgggctccaggcaaggggctagagtggatgggagttatatcatttgatggagataataaatactacacagactccgtgaagggccgattcaccatgtctagagacaattccaagaacacactatatctccaaatgaacagcctgtcagctgaggacacggctgtctattactgtgcgagagatcgagatttcgactttcctgcttacggtttggacgtctggggccaagggaccacggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +18261 JY8QFUQ01CN8I9 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggGggagggactggtgtgggtctcacGggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18262 JY8QFUQ01BK3V9 No results +18263 JY8QFUQ01A9DN8 No results +18264 JY8QFUQ01AC792 productive Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARPAGEGDPFFHYYSGLDVW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18265 JY8QFUQ01DHE9K productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 985 95.37 206/216 nt 94.44 204/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccGtttagtagtcatgtcatgagctgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18266 JY8QFUQ01A840J productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-1*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaaGggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccCccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgattaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcatcgctgcctggtcagggcttcttccc +18267 JY8QFUQ01BR8K6 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18268 JY8QFUQ01CTSDS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGSYLYCFDYW in-frame + cctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtggtgatgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactgctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18269 JY8QFUQ01AH8S9 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 775 84.02 184/219 nt 83.11 182/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); tgtctgggattcacatttagaagctattccatgaattgggtccGgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGgggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18270 JY8QFUQ01CF84W unknown (see comment) Homsap IGHV3-16*01 ORF 94 53.45 62/116 nt 8 X X 8.X.X [25.5.X.X] null - No rearrangement found ctctggattcacctttagtagttctgccatgaactggaggagtctgggggaggcttggttcagccgggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18271 JY8QFUQ01B1X2K unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYFEPYDY## out-of-frame + gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaacccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +18272 JY8QFUQ01B6PJB No results +18273 JY8QFUQ01A953W unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD2-8*01 F 3 8 8 21 8.8.21 [1.17.38.11] CANACPPV*LGNVFLLLRYGTSG in-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); tctggattcaTcgttcagtagcGtatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctgcccccccgtataactgggaaacgtatttctactactacggtatgggacgtctgggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18274 JY8QFUQ01ADV0A productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 974 93.67 207/221 nt 93.21 206/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARHGSGWLQELDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtggctccatcatcagagacagtgcctactGggggctggatccgccagcccccagggaaggggctggagtggcttgggagcatctattatagtgggagtacctactacaatccctccctcaagagtcgagtcaccatatccgtagacacgtccaagaagcagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagacatggcagtggctggctccaggaacttgactactggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18275 JY8QFUQ01A5AIL unproductive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 853 89.2 190/213 nt 88.26 188/213 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.16.38.11] CGRGDGG#DLW out-of-frame - stop codons in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) ctctggattcacggttgaggattatggcgtgagctgggtcgccaagttccagggaaggggctggagtgggtctctggtcttaatttgaatggtgccacaggttatgcaaagtccgtgacgggccggtttaccatctccagagacaacgccaagaactccctgtatttggaaatggatagtctgagagtcgaagacacggccttctattattgtgggagaggggacggggggtgacctctggggccggggaatcctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18276 JY8QFUQ01AVVFN No results +18277 JY8QFUQ01DQOUI unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18278 JY8QFUQ01B0U8B productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +18279 JY8QFUQ01CGQJT unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 118 58.7 54/92 nt 56.52 52/92 nt 8 X X 8.X.X [21.1.X.X] null - No rearrangement found in FR1-IMGT, from codon 14 of V-REGION: 2 nucleotides (from position 101 in the user submitted sequence), (cause frameshift)in FR1-IMGT, from codon 20 of V-REGION: 10 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) ggggggaagaagccctggaccaggcaggcgatgaccacgttcccatctggctgggtgctgcagaggctcagcgggaagaccttggggctggtcggggatgctgggggctggcggatgcagttccaggagtaaccactgaaggacccaccacaga +18280 JY8QFUQ01B9YY8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18281 JY8QFUQ01CRU68 No results +18282 JY8QFUQ01AND2L productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 929 91.4 202/221 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 10 7 18 10.7.18 [1.17.38.11] CARSAYCGADCYSADYLQHW in-frame - tctctggtggctccgtcagcagtaggggttactactggaactggatccgccagttcccagggaagggcctggagtggattgggaacatcttttacagtgggggcacctacgacaacccgtccctcaggagtcgaatttctatatcattagacacgtctaagaaccaattctccctgaagttgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18283 JY8QFUQ01A9PZ9 unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18284 JY8QFUQ01CNHSH productive Homsap IGHV3-72*01 F 962 92.41 207/224 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 10 14 8.10.14 [1.17.38.11] CARLHYSGGWYGLDVW in-frame + cctctggattcaccttcagtgaccactacatagactgggtccgccaggctccaggaaaggggctggagtgggttggccgtactcgaaataaagctaacggttacagtacagagtatgccgcgtctgtgaaaggcagattcaccgtctcaagagatgactcagagaacttagtgcatctgcaaatgaacagcctgaaaagcgaggacacggccctgtattactgtgctagactgcactacagtggtggctggtacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18285 JY8QFUQ01DRLB3 productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18286 JY8QFUQ01CMIFO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + cctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18287 JY8QFUQ01ASQRV No results +18288 JY8QFUQ01CTDQI unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 679 94.08 143/152 nt 8 8 X 8.8.X [1.17.16.X] null + No rearrangement found cctctggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaac +18289 JY8QFUQ01A8464 productive Homsap IGHV4-61*02 F 956 92.76 205/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame + tctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccagccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18290 JY8QFUQ01ARQT4 productive Homsap IGHV3-48*03 F 878 89.45 195/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18291 JY8QFUQ01CD4E0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 8 18 8.8.18 [1.17.38.11] CARESGDYDGKYSKSYLDYW in-frame - cctctgggttcagcttcgattcctataccctgaactgggtccgccagactccagggaaggggctggagtgggtctcatccatcagcagaagtagtagttatgtatactacacagactcggtgaagggccgcttcaccatctccagagacaacgccaggaactccctgtctctgcagatgaacagcctgagagccgaggacacggctgtttattactgtgcgagagaatcgggtgactacgatggtaaatatagcaagtcatatcttgactattggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctagtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18292 JY8QFUQ01CMEU9 unproductive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 2 8 8 X 8.8.X [1.17.38.11] CTREGGRGSSSEDY#LDYW out-of-frame + ctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaggaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtacgcgagagggggggcggggcagttcgtcggaagactactttggactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18293 JY8QFUQ01CCTBO productive Homsap IGHV1-18*01 F 939 93.46 200/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARSHGEQQLDEFDFW in-frame + Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) tggttacatctttaccagctatggtatcagctgggtgcgacaggcccctggacaaggacctgagtggatgggatggatcagctcttacaatgggaacgcaaactttgcacagaagttccacggcagagtcgccatgaccacagacacatcctcgagcacagcctacttggaactgaggagcctgagatctgacgacacggccatgtattactgtgcgagatctcacggggaacagcagctggacgaatttgacttctggggccaggggaccgtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +18294 JY8QFUQ01AVTU7 productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F (see comment) 706 81.02 175/216 nt 79.63 172/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.16.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 66 of V-REGION: 'TACT' (4 nucleotides at position 105 to 108 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaagggccggagtgggtggccaacatatccccagacggaaagtacgaaaaTACTttttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18295 JY8QFUQ01AUH7W No results +18296 JY8QFUQ01DRN8J productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 848 87.33 193/221 nt 86.88 192/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [2.17.38.11] CAKYSGGWTSIFDGW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'AT' (2 nucleotides at position 16 to 17 in the user submitted sequence), (cause frameshift); cagcctctggattaaATtttttcccagtatggccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactgttagtggtgatgctggtgacatatactacgcagactccgtgaggggccggttcaccatctcgagagacaattccaagaacacggtcattctgcagatgaacagcctgagagtcgaggatacggccatatatttctgtgcaaaatatagcggtggctggacatcgatttttgacggctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18297 JY8QFUQ01C8G26 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 807 85.45 188/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + ctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactc +18298 JY8QFUQ01BB8B1 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 899 91.16 196/215 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01BB8B1 ; 7 AA in Homsap_IGHV3-53*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggattcaccgtcaatagaaactacatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18299 JY8QFUQ01BMPPM productive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARCPNYNIGTRGFDYW in-frame + tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +18300 JY8QFUQ01CGV8T productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F (see comment) 783 83.19 188/226 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 10 13 8.10.13 [2.17.38.11] CSTGGPNGYHSTYPW in-frame - Low V-REGION identity (83,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) agcctctggattcgccttcaatatcaagtggatgagttgggtccgccaggctccggggaaggggcttgagtgggtcggccgcatcaagagcagcgctgatggtgcgacaacagacaccattgagcgcgtgagagacagattcaccatctcaagagatgactcaaaaaatacactgtacttgcacatgaccagcctgagaaccgaggacacaggcatgtattattgttccacaggcgggccaaatggatatcactccacatatccctggggcccggggacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18301 JY8QFUQ01C0KMS unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +18302 JY8QFUQ01A5AW4 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18303 JY8QFUQ01DECQU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 878 89.45 195/218 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD6-25*01 F 3 8 8 15 8.8.15 [1.17.38.11] CVRGGRGQQREDAFDIW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctctggattcatcttcagtagttatagtttgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatatgagtagttcttacatctattatggagactcagtgaggggccgatttaccatctccagagacaacgccgagagctcactgtatctgcagatgagcagcctgagagccgaggacacggctttatattattgtgtgagaggcgggagggggcagcagcgagaagatgcttttgacatttggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +18304 JY8QFUQ01BMLP2 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CARAKRFGAPP#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagcaaaaaggttcggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18305 JY8QFUQ01AGKQJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18306 JY8QFUQ01A7D7G productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +18307 JY8QFUQ01CN6AC productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 866 90.09 191/212 nt 89.15 189/212 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.16.38.11] CAREFRAPSLARYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaagggctggagtgggtctcagTttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18308 JY8QFUQ01A5XDS productive (see comment) Homsap IGHV1-2*02 F 939 93.46 200/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 82 to 87 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18309 JY8QFUQ01CR20N No results +18310 JY8QFUQ01C4YE8 productive (see comment) Homsap IGHV3-9*02 F (see comment) 729 82.03 178/217 nt 80.65 175/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-9*01 F 2 8 8 19 8.8.19 [1.17.38.11] CVKDKDKVGGHTGHYPTFDFW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 93 of V-REGION: 'A' (1 nucleotides at position 183 to 183 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 99 of V-REGION: 'G' (1 nucleotides at position 204 to 204 in the user submitted sequence), (cause frameshift); ctctggattcaaccccgaaaactttgccatgcactgggtccgacaagttccagggaagggAcctgaagtgggtctcaggtataaattggaatggacgaaaaacaggatatgcggagtctgtgaggggccggttcaccatctccagagacaatgacaagaacgtcctttctttgcaaatgaccAattttggggactgaggacacGggccttctatttttgtgtgaaagataaggacaaagtggggggccacactggccattatcccacgtttgacttctggggccagggagccctggttaccgtcgcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18311 JY8QFUQ01ACVZ2 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 94 52.24 70/134 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18312 JY8QFUQ01B93WH productive (see comment) Homsap IGHV4-61*02 F 987 94.55 208/220 nt 93.64 206/220 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.37.11] CATVARRGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 96 of V-REGION: 1 nucleotides (from position 195 in the user submitted sequence), (cause frameshift) tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggGggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgaccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18313 JY8QFUQ01AV2V7 productive Homsap IGHV3-72*01 F 930 91.03 203/223 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-3*01 F 2 8 10 14 8.10.14 [1.17.38.11] CLRGFSSHYRGGMDVW in-frame - ctctggactcacgttcagtgaccactacatggactgggtccgccagactccagggaggggactggagtgggttggccgtattagagacaaagctcgcaggtacaccacagaatacgccgcgtctgtgaaaggcagattcaccattttaggagatgatttaaagaattcactgtatctacaaatgaacaacctgagaaccgacgactcggccgtgtattactgtctcagaggattttcgagccattatcggggcggtatggacgtctggggccaagggaccacggtcaccgtgtccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18314 JY8QFUQ01B0Z32 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASDLGGQKSYW in-frame + ctcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18315 JY8QFUQ01CJVW9 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 86 of V-REGION: 'C' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccaCgttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18316 JY8QFUQ01AQQDB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 888 89.55 197/220 nt 89.09 196/220 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); aggctctgacttGcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18317 JY8QFUQ01BCZ6T productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 908 91.63 197/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame + cctctgggttcaccgtcagtagcaagttcatgagctgggtccgccagggtccagggaaggggctggagtgggtctcagttacttatcctgatggtactacacattatagagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18318 JY8QFUQ01CI4FK unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctggattcaccttcatcagttatggcatgagttgggtccgccagtTttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtatattactgtgcgagagggtacagtcaaaaatggggtttttcgaccactggggccaggggtaatcctggtcaccgtttccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccga +18319 JY8QFUQ01BNSUQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18320 JY8QFUQ01AW4RF productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18321 JY8QFUQ01CHX7Q productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 957 92.38 206/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.38.11] CTHLREEMSYEW in-frame + ctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +18322 JY8QFUQ01C37YG productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame - cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18323 JY8QFUQ01C1L9B productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - ctctagggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18324 JY8QFUQ01BAA2B productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 199 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.38.11] CARGRTVVTVIDYIDYW in-frame + ctctggggactccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcaggganccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18325 JY8QFUQ01B1FGN unproductive Homsap IGHV3-13*01 F 961 94.84 202/213 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD1-1*01 F 1 8 7 X 8.7.X [1.17.38.11] CARGSSKAYNWFD#PW out-of-frame - tctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18326 JY8QFUQ01CERMV unproductive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt 97.25 212/218 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSSPYFYDSNGY## out-of-frame + in FR2-IMGT at codon 43 of V-REGION: 'C' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); cctctggattcaggtttagcatctattggatgagctgggtccCgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccaggggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttcccccag +18327 JY8QFUQ01AQALS productive Homsap IGHV4-61*01 F (see comment) 767 83.26 184/221 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame - Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18328 JY8QFUQ01BSME5 productive (see comment) Homsap IGHV4-4*07 F 872 89.77 193/215 nt 88.37 190/215 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 7 12 8.7.12 [1.17.38.11] CARFSSYGDTFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'A' (1 nucleotides at position 209 to 209 in the user submitted sequence), (cause frameshift); tctctgatgggtccatcggaagttactactggacttggatccggcagcccgccgggaaggcaatggagtCggatcgggcgtgtctttagaactCgggaacacgaattacaacccctccctcaagagtcgggtcaccatgtcagttgacacgtccaagaatcaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgAttttactgtgcgagattctcgtcctacggtgacacctttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18329 JY8QFUQ01BRRDS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CARGDSADAYNYYRYW in-frame + ctctggattcaccttcactagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatagtgatggaagtagtacaacctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtctctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaggggatagtgcagatgcctacaattactaccgctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18330 JY8QFUQ01DCYKK unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18331 JY8QFUQ01CMWEB No results +18332 JY8QFUQ01CLVE2 productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggagccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18333 JY8QFUQ01B7ESX No results +18334 JY8QFUQ01B1R6X No results +18335 JY8QFUQ01AHYYV unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +18336 JY8QFUQ01CNZMZ productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18337 JY8QFUQ01A34DZ productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + cctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacgactgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttccccgctgagcctcgacagcacccccccgaagatgggaaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +18338 JY8QFUQ01B3HC3 productive (see comment) Homsap IGHV2-5*02 F 1134 96.31 235/244 nt 95.49 233/244 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-17*01 F 3 10 7 13 10.7.13 [9.17.38.11] CAHFSVTTPYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 183 to 183 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttctctgggttctcactcaccactactggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcagtcaCttttttgggatgatgatgagcgccacagcccatctctgaggagaaggctcaccatcaccaaggacatctccGaaaaaccaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacttttcggtgactaccccatatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18339 JY8QFUQ01CGPHQ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18340 JY8QFUQ01CLXF8 unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F 850 88.43 191/216 nt 87.96 190/216 nt 8 7 X 8.7.X [2.17.38.X] null + No rearrangement found in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); gtacacggcgggtccttcaaaggttactattggagctggatccgccagcCccccaggaaaggggctggagtggattggagaaatcgaccatagtggaaacaccaactacaacccgtccctcaagagtcgagtcaccgtgacagttgacacatccaagaaccaaatttccctgaatttgacctctgtgaccgccgcggacacggctatttattactgtgcgcgtatttcagcctttgaccagtggggccagggtaacccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +18341 JY8QFUQ01AZCNQ No results +18342 JY8QFUQ01CZ0AN unproductive Homsap IGHV3-48*02 F 1031 97.25 212/218 nt 96.79 211/218 nt Homsap IGHJ5*01 F 102 66.67 34/51 nt Homsap IGHD1-1*01 F 3 8 8 X 8.8.X [1.17.38.11] CASGGKERLRSTTGLLSRHGRL# out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggactcaccttcagcagctatagtatgaactgggtccgccaggctccagggaaggGggctggagtgggtttcatatattagtagtactagtagtaccataaactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagtgggggaaaggaaagactacgaagtacgacgggactactatcacggcatggacgtctgggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18343 JY8QFUQ01BXM61 unproductive Homsap IGHV3-7*01 F 913 91.67 198/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [1.17.38.11] CARGSYWHYDTFGDY#W out-of-frame - tctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactatttggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18344 JY8QFUQ01C76VU unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 204 to 204 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacgGgctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18345 JY8QFUQ01BNIBW productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18346 JY8QFUQ01APFLG unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 847 87.67 192/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKDKWYYDSSGFA##YLDYW out-of-frame + stop codons gcctctgggttcgccgtcagtagcaagttcatgagttgggtccgccaggctccagggaaggggctggagtgggtcgcagctatgagtggaggtggtggtggtgtgttctatgcagactccgtgaagggccggttcaccatctccagagacaattccaggaataccctgtatttgcaaatgaatagcctgagagccgaggacacggccgtatattattgtgcgaaagacaaatggtattatgatagtagtggttttgcaggactaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18347 JY8QFUQ01A1MJU productive (see comment) Homsap IGHV3-9*01 F 931 92.59 200/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'C' (1 nucleotides at position 143 to 143 in the user submitted sequence), (cause frameshift); tctggattcaccGtttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaagGggccgattcaccgtctcCcagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18348 JY8QFUQ01B5OF8 productive Homsap IGHV3-9*02 F 901 90.41 198/219 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD2-2*01 F 3 8 8 12 8.8.12 [2.17.38.11] CGKDMRPGGMDVLG in-frame - gcctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtcttgggggccagggggatcacggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18349 JY8QFUQ01CI60Z productive Homsap IGHV3-11*01 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame - cctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggctttcatacattagtggtagtggaactaccatatcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaggaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgaggcgggtgtggggatatagttatggttccgtttcgtactactttgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagatcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18350 JY8QFUQ01BRBCP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - ctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18351 JY8QFUQ01DVVPI productive (see comment) Homsap IGHV3-7*01 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-21*02 F 3 8 8 9 8.8.9 [2.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gcctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaAaggggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggctgacggtgtcgtggaacctcagg +18352 JY8QFUQ01A1XCW No results +18353 JY8QFUQ01CCB8B productive (see comment) Homsap IGHV1-18*01 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-10*01 F 3 8 8 11 8.8.11 [0.17.38.11] CVRVIRTNWLDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 77 of V-REGION: 'A' (1 nucleotides at position 131 to 131 in the user submitted sequence), (cause frameshift); tggttacacctttactacctatggcgtcacctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggtaatacaaactctgcacagaagtttcaggacagagtcAaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacagccgtatattattgtgtgcgagtgattcggaccaactggctcgacccctggggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18354 JY8QFUQ01CXKOE productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 997 96.26 206/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFYYW in-frame - tggatacaccttcaccagctactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagntacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagacttttactactggggccagggaaccctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18355 JY8QFUQ01CG25J No results +18356 JY8QFUQ01CR2LQ productive Homsap IGHV3-7*01 F 851 88.07 192/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRDRPGGWALDYW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) cctctggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcagg +18357 JY8QFUQ01BOX9A productive (see comment) Homsap IGHV4-61*02 F (see comment) 740 81.9 181/221 nt 81.0 179/221 nt Homsap IGHJ4*03 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERAPSIDGVRELDFW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,90% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 35 of V-REGION: 'CT' (2 nucleotides at position 27 to 28 in the user submitted sequence), (cause frameshift); tctctggtggActccattaccagtggCTtttttactactggaattggatcagacagcccgccgggaggggactggagtggatcggacgtgtctatattactgggagtgtcaactacagtccatccctcgaacacagagtcagtatatctctagacacgtccaagaggcaattcttcttgaggttggtctctgtgaccgccgcagacacggccgtgtattactgtgcgagagagcgggctccttcgattgacggagtgagagaacttgacttctggggccaggggaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18358 JY8QFUQ01B23SC productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 947 92.31 204/221 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAREVIPTATYGMDLW in-frame - Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cagcgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18359 JY8QFUQ01CDCTW unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 358 86.32 82/95 nt 8 5 X 8.5.X [1.17.X.X] null + No rearrangement found cctctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc +18360 JY8QFUQ01A0GVY productive Homsap IGHV3-9*01 F 810 86.18 187/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD5-24*01 ORF 3 8 8 17 8.8.17 [1.17.38.11] CVKDRKAGGYNLLDAFDIW in-frame + ctctggattcaccttcgacgactatgtcatgcattgggtccggcaagttccagagaggggcctggagtgggtcgcaggcattaatggggaaagtaatagttttggctctgtggactctgtaaagggccgattcaccatctccagagacaaggccaagaataccctgtatttgcaaatgaatagcctgagagttgaggacacggccttgtattattgtgtgaaagatagaaaagctggtggctacaatctgttggatgcttttgatatctggggccaagggacaatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18361 JY8QFUQ01BFY8U productive Homsap IGHV3-48*02 F (see comment) 739 81.74 179/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [2.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,74% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18362 JY8QFUQ01BQUDF productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18363 JY8QFUQ01CJPZK productive Homsap IGHV4-61*03 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 10 7 12 10.7.12 [1.17.38.11] CTRHPKSNVEGDSW in-frame + tccctggtggctccgtcagcagtggtagttatttctggagctggatccggcagcccccagggcaggggctggaatggatcggttatgtctataacaatgggaacaccaattacaacccttccctcaagagtcgagtcaccatttctatagacacgtccgagaatcacgtctccctgaagctggcctctgtgaccgctgcggacacggccgtgtactactgtacgaggcacccgaagtctaatgtagagggtgactcctggggccagggagccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18364 JY8QFUQ01AVAG4 No results +18365 JY8QFUQ01DHQ86 productive (see comment) Homsap IGHV3-74*03 F (see comment) 788 84.86 185/218 nt 83.94 183/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 30 of V-REGION: 'TC' (2 nucleotides at position 17 to 18 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcacgttTCcacacctcctggatggcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaAagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18366 JY8QFUQ01B3AJ9 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 923 91.74 200/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKAGRGLIRPNNWFDPW in-frame + cctctggatttaccttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcggggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18367 JY8QFUQ01AIGUU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 693 80.18 174/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGLGLNAVYAFDVW in-frame - Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcgcttttggagattatgccatgaactgggtccgccaggccccagggaagggactggagtgggtctcaggtttgagcggtagaggcgtcagcaaatattatgcagactccgtgaggggccggttctccatttccagagacaactccgggagcgaggcagtccttcaaatgagcagcctgagagtcgaggacacggccacttactactgtgcgaggggcctagggcttaatgctgtctacgcatttgacgtctggggacaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +18368 JY8QFUQ01AV9D1 productive Homsap IGHV4-39*02 F 956 92.76 205/221 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 10 7 12 10.7.12 [1.17.38.11] CASVTTVSMRMKYW in-frame + tctctggtggctccatcagcagtgatagttactactggggctggatccgccagtccccagggaaggggctggagtggattgggaatatctattatcgtgggagcacctattacaacccatccctcgagagtcggctcaccatgtcggtagacacgtccaggaacctcttctccctgaggctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagcgtgactacggtgtctatgaggatgaaatactggggccggggaaccccggtcaccgtctcctcagcatcccccgaccagccccaaggtcttccccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18369 JY8QFUQ01BR9Z6 unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*05 F (see comment) 302 75.23 82/109 nt 8 10 X 8.10.X [1.17.X.X] null - No rearrangement found Low V-REGION identity (75,23% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcactttcagtgacgcctggatgagctgggtccgccagattccagggaaggggctggagtgggttggtcgtcgcatgcctggtccagggcttcttccccca +18370 JY8QFUQ01C8V2I unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1031 97.25 212/218 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD4-11*01 ORF 3 10 7 X 10.7.X [0.17.38.11] CARLDYTRYFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccaa +18371 JY8QFUQ01B801I No results +18372 JY8QFUQ01AXBDD unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 96 55.91 52/93 nt 54.84 51/93 nt 8 X X 8.X.X [17.6.X.X] null - No rearrangement found in FR1-IMGT, from codon 17 of V-REGION: 24 nucleotides (from position 107 in the user submitted sequence), (do not cause frameshift) gggggaagaagccctggaccaggcaggcgatgaccacgttcccatctggctgggtgctgcagaggctcagcgggaagaccttgggggctggtcggggatgctgggggccgccggatccaactccagtagtaaccagtcatggagccaccagaga +18373 JY8QFUQ01BL763 productive Homsap IGHV1-2*02 F 858 89.25 191/214 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARGVDHRSVGYILW in-frame + cggatacactttgaacgactactatatgcactgggtgcgacaggcccctggacaagggtttgagtggatgggatggatcaaccccaacaatggtgacacaaaatattcacagaaatttcagggcagggtcaccatgaccagtgacacgttcagtagaacagcctacatggagctgaccagggtgaggtctgacgacacggccatttattattgtgcgaggggagtcgatcatcgtagtgttggatatatcctatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18374 JY8QFUQ01A5WAH unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame + cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgagcagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18375 JY8QFUQ01DWADM No results +18376 JY8QFUQ01C7CFD unproductive Homsap IGHV4-61*02 F 884 89.14 197/221 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD5-24*01 ORF 1 10 7 X 10.7.X [1.17.38.11] CARDFGGSYNLVAY## out-of-frame + tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18377 JY8QFUQ01C9SXB productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame - ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18378 JY8QFUQ01CFSPR productive (see comment) Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 99.54 215/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.37.11] CASRLRSSGGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 99 of V-REGION: 2 nucleotides (from position 201 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18379 JY8QFUQ01BZGM7 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 896 90.37 197/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) ggcctctggattcacCctttggttattatggcatgactggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18380 JY8QFUQ01DNP7Q productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARDMGSGRYFEPYDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggGggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccaaaccggtgacggtgtcgtggcaactca +18381 JY8QFUQ01AM5G1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 650 83.24 154/185 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD4-11*01 ORF 3 X 8 X X.8.X [X.15.38.11] DSRNPRV# out-of-frame - Low V-REGION identity (83,24% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gtggggtccgccaggctccagggaaggggctggagtgggtctcagggctttgtggaagtgctcctaccacacactacgcagactccgtgaagggccggttcagcatctccagagacctctccaagaatgttctgtttctgcaaacgagcagcctgagagccgaggacacgaccgttttttctgactccagaaatcccagggtaggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18382 JY8QFUQ01CXLNY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + tctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18383 JY8QFUQ01BRBL7 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 773 84.65 182/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.38.11] CARGRTVVTVIDYIDYW in-frame + Low V-REGION identity (84,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggggactccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18384 JY8QFUQ01CX0IT No results +18385 JY8QFUQ01BIXBY productive (see comment) Homsap IGHV4-61*02 F 806 85.78 187/218 nt 84.4 184/218 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD4-23*01 ORF 2 9 7 17 9.7.17 [1.17.38.11] CARGECGVNCPYYNWYQHW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'ATG' (3 nucleotides at position 25 to 27 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 3 nucleotides (from position 24 in the user submitted sequence), (do not cause frameshift) tgtctggtggctccatcagcagtgATGattactactggagctggatacggcagtccgccgggaagggactggagtggattgggcgaatttataaaagtggcgacacagtgtacaaccCcctccctcggggggcgagtcgccatgtcactggacacgtccaagaaccaattctccctgaggttgacttctgtgaccgccgaagacacggccgtctattactgtgcgaggggtgagtgcggtgtcaactgcccctactacaactggtaccaacactggggcccgggaacccgggtcaccgtcacgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +18386 JY8QFUQ01B9IG9 unproductive (see comment) Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CVKDMVAGQGLLSR#FDHW out-of-frame + stop codons Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggttttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +18387 JY8QFUQ01BB5AY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18388 JY8QFUQ01BREZ1 unknown (see comment) Homsap IGHV3-7*01 F 856 88.13 193/219 nt 87.67 192/219 nt 8 8 X 8.8.X [2.17.38.X] null + No rearrangement found in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); cctctggttttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctattTtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggctttattgacgtactggggccctgggaaccgcgggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgatgtcgtggaact +18389 JY8QFUQ01DGM8L productive (see comment) Homsap IGHV4-39*03 F 893 89.55 197/220 nt 88.64 195/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'TGG' (3 nucleotides at position 73 to 75 in the user submitted sequence), (do not cause frameshift); tctccggtggctccatcaacagtagaaAattattattggggctggatccgccagccccccagggaagggtttTGGgagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18390 JY8QFUQ01BTGUH unproductive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 816 85.91 189/220 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD1-1*01 F 1 8 8 X 8.8.X [2.17.38.11] CVRDLNWS#FDSW out-of-frame - stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) agcctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtctttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18391 JY8QFUQ01DVFZP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 867 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tccgaattcatccttgacagttatgccatgagttgggnccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18392 JY8QFUQ01DDHMO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18393 JY8QFUQ01DMQSJ unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CACYLIVMV#FDYW out-of-frame + ttctggatacgtctttccctcctactggatcgcctgggtgcgccagatgcccggtaaaggcctggagtggctgggaaccatctatcccggcgactctgacaccacatacagcccgtcattccaaggccaggtcaccatgtcagtcgacacgtccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacagcgccatttactattgtgcgtgttatttgatagtaatggtttctttgactactggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18394 JY8QFUQ01B71U8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F (see comment) 256 90.32 56/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18395 JY8QFUQ01BT0YR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18396 JY8QFUQ01C9KK4 No results +18397 JY8QFUQ01CIKKB productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*10 F or Homsap IGHV3-30*16 F or Homsap IGHV3-30*17 F or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*03 F 524 89.31 117/131 nt 88.55 116/131 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 X 17 8.X.17 [1.3.31.11] CARDSVPRASEAAYHFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 39 in the user submitted sequence), (do not cause frameshift) cctctggattctccttcagaagttactctttccactggggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18398 JY8QFUQ01AVZ3U No results +18399 JY8QFUQ01A2E6C unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +18400 JY8QFUQ01BDTL8 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 846 88.02 191/217 nt 87.1 189/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 7 8 17 7.8.17 [2.16.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) gcctctggattcagtttagtacacatggcatgaactgggtccgccaggctccagggaagggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18401 JY8QFUQ01BO500 No results +18402 JY8QFUQ01BXZ5F No results +18403 JY8QFUQ01AHTIX productive (see comment) Homsap IGHV3-30*08 F 886 90.28 195/216 nt 88.89 192/216 nt Homsap IGHJ6*01 F 243 87.3 55/63 nt Homsap IGHD6-6*01 F 1 7 8 18 7.8.18 [2.16.38.11] CARDRPPSSTSYHYNGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 30 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) gcctctgcattcaccttcagtagtatgctttcactgggtccgccaggctccaggcggggactagagtggctgtctgttgtatcagcggatggaagtataaaatactacgcagactccgtgaagggccgattctccatctccagagacaactccaggaacacgctgtctctacaaatgaacagcctgagcgctgaagacacggctgtttattattgtgcgagagatcgccctccgagcagtacgtcctaccactacaacggaatggacgtctggggtcaagggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +18404 JY8QFUQ01CCO0P unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFD#PW out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18405 JY8QFUQ01CT185 productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaactcag +18406 JY8QFUQ01CK21C productive Homsap IGHV3-72*01 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame - cctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18407 JY8QFUQ01AKT55 No results +18408 JY8QFUQ01AX0TL productive (see comment) Homsap IGHV4-61*02 F 892 89.95 197/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.16.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctccggtggctccatcagtactggttattactactGggagctggatccggcagtccgccgggaagggactgaatggattgggcgcatgtctgccagagggggAcagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18409 JY8QFUQ01C2RYU unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18410 JY8QFUQ01DOFXP No results +18411 JY8QFUQ01B1O2N productive Homsap IGHV1-8*01 F 840 87.85 188/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARVGGTHYHYGVDVW in-frame - cggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagatctgacgacacggccgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18412 JY8QFUQ01BEAS9 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +18413 JY8QFUQ01BVECJ unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 112 64.52 40/62 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CGGQWQGS#YGINVW out-of-frame + stop codons cctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtggcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18414 JY8QFUQ01DUA6W productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 939 93.46 200/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 9 7 13 9.7.13 [X.16.38.11] CARHGSGWLQELDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'CC' (2 nucleotides at position 71 to 72 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) gtggctccatcatcagagacagtgcctactggggctggatccgccagccccagggaaggggctggagtggCCtttgggagcatctattatagtgggagtacctactacaatccctccctcaagagtcgagtcaccatatccgtagacacgtccaagaagcagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagacatggcagtggctggctccaggaacttgactactggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18415 JY8QFUQ01BBYMD No results +18416 JY8QFUQ01C7YWX No results +18417 JY8QFUQ01CM56B No results +18418 JY8QFUQ01CMHLV productive (see comment) Homsap IGHV4-61*01 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcCccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18419 JY8QFUQ01ATT4K productive (see comment) Homsap IGHV3-11*04 F (see comment) 875 90.57 192/212 nt 90.09 191/212 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.16.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01ATT4K ; 8 AA in Homsap_IGHV3-11*04) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 45 in the user submitted sequence), (cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccagctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18420 JY8QFUQ01B62FK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +18421 JY8QFUQ01CBXL5 No results +18422 JY8QFUQ01AYJKR productive Homsap IGHV1-69*02 F 930 92.52 198/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD1-26*01 F 3 8 8 18 8.8.18 [0.17.38.11] CATYSGTYGATSTGGAFDIW in-frame + tggaggcaccttcagcatctatactgtcaactgggtgcgacaggcccccggacaagggcttgagtggatgggaaggatcatctctctccttgatatagcgcactacgcacagaagttccagggcagagtcacgattgccgcggacaaatcctcgggcacagtctacctggagctgagcagcctgagatctgaggacacggccatgtattactgcgcgacatatagtgggacatacggcgcgacgagcacgggaggtgcttttgatatttggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18423 JY8QFUQ01C6S8D productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 856 88.13 193/219 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARQLSGDYASFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggtgcctccatcaccagtggtactttttactgggcctggatccgccagcccccagggaaggggctggagtgggttggcaatatctattctagtggtgtcgcctattacaacccgtccctcaagagtcgagtcaccatgtccgtcgacacgtccaagaatgagttttccctgacactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18424 JY8QFUQ01BVAO1 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 662 77.98 170/218 nt 77.52 169/218 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIVREGLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (77,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tgtctggtggctccatcgccacttatcattggtggaActtgggtccgccagacccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18425 JY8QFUQ01AVIDH No results +18426 JY8QFUQ01ASLIK productive (see comment) Homsap IGHV3-7*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'TT' (2 nucleotides at position 20 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacctttagTTtatcactgggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18427 JY8QFUQ01B7F74 No results +18428 JY8QFUQ01CUNM7 unproductive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18429 JY8QFUQ01AW12K productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [2.16.38.11] CARDQSLGMPEAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtcgctatagcatgaactgggtccgccaggtccagggaaggggctggantgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18430 JY8QFUQ01CGODV unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18431 JY8QFUQ01DI18G productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtactcattactattggggctggatccggcagcCccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca +18432 JY8QFUQ01A6FSC productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + ctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgctctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgacgagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18433 JY8QFUQ01BPAT4 No results +18434 JY8QFUQ01B1HC5 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 950 93.12 203/218 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 7 10 9.7.10 [1.17.38.11] CASHGGKYFPQW in-frame + tctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggacaaatccatcatggtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccgag +18435 JY8QFUQ01B9P2E No results +18436 JY8QFUQ01CGPMH No results +18437 JY8QFUQ01B1ZOE productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 924 91.36 201/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18438 JY8QFUQ01BSC7V productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + cctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18439 JY8QFUQ01B9FD1 No results +18440 JY8QFUQ01AMSQI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18441 JY8QFUQ01CI8F2 productive (see comment) Homsap IGHV3-33*03 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18442 JY8QFUQ01AJOP1 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 907 90.09 200/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARHSRLVRYFEFW in-frame - gtctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +18443 JY8QFUQ01BARSA productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 718 82.16 175/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDWGGSFDRYYFDYW in-frame + Low V-REGION identity (82,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release caccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccga +18444 JY8QFUQ01BJ7VH productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +18445 JY8QFUQ01BI347 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 824 86.7 189/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 2 9 7 15 9.7.15 [1.17.38.11] CTSREHAFSGQFTGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'CGT' (3 nucleotides at position 23 to 25 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'TG' (2 nucleotides at position 53 to 54 in the user submitted sequence), (cause frameshift); tgtctggtgtctccgtcaccagCGTcagtcactggtggacctgggtccgccaTGgcccccagggaagggactggagtggattggagaaatctattattatggcatcaccaatttcaacccgtccctcaagagtcgaatcagcatgtcagtggacgagtccaagaaccagttctccctgagactgacttctgttaccgccgcggacacggccgtttattattgtacgagtcgcgaacatgcttttagtggtcaattcacgggtgactactggggccagggaaccctgatgaccgtcacctcagcctccaccaaaggggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18446 JY8QFUQ01C5RB9 No results +18447 JY8QFUQ01BXYQU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca +18448 JY8QFUQ01CYLM9 unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CAGHLLGD#FDYW out-of-frame + ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgaccctttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +18449 JY8QFUQ01B3LQ2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18450 JY8QFUQ01CT2EE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18451 JY8QFUQ01BKNEI productive (see comment) Homsap IGHV3-9*01 F 887 89.91 196/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'G' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); cctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtAgggtctccggtatcactgggaatagtggttccataggcGtatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18452 JY8QFUQ01CM8GM No results +18453 JY8QFUQ01DR5LI unknown (see comment) Homsap IGHV3-7*01 F 1035 97.7 212/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +18454 JY8QFUQ01CN5UO productive Homsap IGHV4-34*10 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame + tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18455 JY8QFUQ01BXRIG productive Homsap IGHV4-4*01 F, or Homsap IGHV4-4*02 F or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 878 89.45 195/218 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 2 9 7 14 9.7.14 [1.17.38.11] CARDKDVTARGTFDMW in-frame - tctctggtgtctccatcagtagtaattactggtggatttgggtccgccagtccccaggggaggggctggagtggattggagaagtctatcatactgggaccacctattacaacccgtccctgaagagtcgagtcaccctgtcagtagacaagtccaggaatcagttctccctggagatgacttctgtgaccgccgcggacacggccgtgtatttctgtgcgagagataaagacgtgacagctcgtgggacctttgatatgtggggccaggggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt +18456 JY8QFUQ01A6M4U unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 447 93.14 95/102 nt 8 7 X 8.7.X [1.17.X.X] null + No rearrangement found cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgaca +18457 JY8QFUQ01CQQFN productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 947 92.31 204/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARQSFDFAWQWQVDYYFEYW in-frame + tctctggtggctccgtcagcagtagcacttactactggggctggctccgccagtccccagggaaggctctggagtggattgggactatccatcatagtgggagcacctaccagaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaggaaccagttctccctgaggctgagctctgtgaccgccgcagacacggctctttattactgtgcgagacaaagctttgatttcgcgtggcagtggcaggtagattattactttgaatactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +18458 JY8QFUQ01AYXXC No results +18459 JY8QFUQ01BOIBX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18460 JY8QFUQ01CYOK3 No results +18461 JY8QFUQ01C2SL2 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGASSDSWR#FDYW out-of-frame + stop codons cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagaggggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18462 JY8QFUQ01AOZ8H unproductive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [0.17.38.11] CAKGSFDSSGRPEAFDIW in-frame - stop codons in CDR2-IMGT at codon 63 of V-REGION: 'TG' (2 nucleotides at position 92 to 93 in the user submitted sequence), (cause frameshift); tggaggcaccttcagtagatatgctttcagctgggtgcgacaggcccctggacaagggcttgagtggatgggagggatcgtccctctctttTGgttccataaaagtacgcacagaagtaccagggcagagccacgattaccgcggacgaatccacgagcacagtctacatggagctgagcagcctgagatctgacgacacggccatgtattactgtgcgaagggttcctttgatagtagtggtcgccctgaggcttttgatatctggggccaagggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18463 JY8QFUQ01CY71J productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame - cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18464 JY8QFUQ01B4XTM productive Homsap IGHV1-69*06 F, or Homsap IGHV1-69*14 F 984 95.79 205/214 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD5-12*01 F 3 8 8 19 8.8.19 [0.17.38.11] CAREVSGYDLTVAGWWGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tggaggcaccttcagcagctatgctatcagctgggtgcgacaggcccctggacaagggcttgagtggatgggagggatcatccctatgtttggaaatccaaactacgcacagaagttccagggcagagtcacgataaccgcggacaagtccacgaacacagcctacttggagctgagcagcctgagatctgaggacacggccgtgtattactgtgcgagagaagttagtggctacgatttaacagtcgcggggtggtggggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc +18465 JY8QFUQ01BO261 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttccccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18466 JY8QFUQ01BE2FF productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 960 93.18 205/220 nt 92.73 204/220 nt Homsap IGHJ6*02 F (see comment) 211 82.26 51/62 nt Homsap IGHD1-20*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARDLRHYSYGFDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcaataattatatgatgaactgggtccgccaggctccggggaaggggctggagtgggtctcatCcctttaggagtagtgataattacatattctacgcagactcagtgaagggccgattcaccctctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgatgacacggctgtgtattactgtgcgagagacctgaggcattactcctacggtttcgacgtctggggccaagggacaacggtcaccgtctcctcagcttccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtatcgtggaactcag +18467 JY8QFUQ01BW7GR productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame + tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +18468 JY8QFUQ01BUKLE productive Homsap IGHV3-30*07 F, or Homsap IGHV3-30*16 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYYFDSW in-frame + ctctggattcaccttcagtatttattctatgcattgggtccgccaggccccaggcaaggggctagagtgggtggcagttatatcacatgatggaactaataaatattactcagactccgtgaagggccgattcaccatctccagagacaattccaagagcgcgctgtatctgcagctgaacgtcctgagcgccgaggacacggctgtctatttctgtgcgagagattccgtacctcgggcgtcagaggctgcctactactttgactcttggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +18469 JY8QFUQ01ANOBA productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 683 80.0 172/215 nt 79.53 171/215 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 99 in the user submitted sequence), (do not cause frameshift) cctctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgacgagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca +18470 JY8QFUQ01BR7IW unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 974 93.67 207/221 nt 93.21 206/221 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD3-16*01 F 3 10 7 X 10.7.X [1.17.38.11] CARHPRPGTFDYLGGGWFD#PG out-of-frame - in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactgggcctggatccgccagcccccagggaaggggctggagtgccttgggagcatcttttatagtgggcgcaccaaccaggacccgtccctcaagagtcgagtcaccCttatccgttgacacttccaagaaccagttctccctgaagctgagctctgtggccgccgcagacacggctgtgtattactgtgcgagacatccccgcccgggaacttttgactacttaggggggggttggttcgacccctgggggccagggaattccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18471 JY8QFUQ01AB2ZQ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18472 JY8QFUQ01CZ2LW productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 821 85.97 190/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQWLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtGactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgaggTaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaatggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18473 JY8QFUQ01CNI6X productive Homsap IGHV3-9*02 F 896 90.37 197/218 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + cctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18474 JY8QFUQ01AX5HQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 554 92.97 119/128 nt 92.19 118/128 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 X 16 8.X.16 [2.6.26.11] CAKEQRGSGWSRSALDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 91 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18475 JY8QFUQ01CLJ2N productive Homsap IGHV1-3*01 F (see comment) 351 73.53 100/136 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 X 7 14 X.7.14 [X.X.38.11] CARGRYDSSGRGHEYW in-frame - Low V-REGION identity (73,53% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcaccagtttcagtatccattggaagttccaggacagactcaccattactagagacacatccgcgagcacagcctacatggacctgagcagcctgagatctgaagacacggctgtctattactgtgcgagagggcgctatgatagtagtggtcgtggccatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggttttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18476 JY8QFUQ01AKPS7 productive (see comment) Homsap IGHV4-34*06 F (see comment) 701 80.84 173/214 nt 80.37 172/214 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 14 8.7.14 [1.17.38.11] CSRGGQSAGWHSFEAW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); tccatggtgggtccctcaGggggttacccctggacctggatccgccacaccgcagagaagggactggagtggattggtcaaatcaatagtgatggaaggacaacctacaactcggccctcatgggtcgagtcaccatttcaacagacacatccaagaatcagttctcgctgactgtggtttctgttgtcgccgcggacacggcaatgtattattgttcgagaggaggccaaagtgctggctggcactcctttgaagcctggggccagggaacccaggtaatcgtcacctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +18477 JY8QFUQ01BX9JE productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame + ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgtctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaaagagcacctctgggggcacagcggccctggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag +18478 JY8QFUQ01B2HDD productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactcag +18479 JY8QFUQ01CBRXW productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 923 91.74 200/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.37.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 70 of V-REGION: 1 nucleotides (from position 121 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 178 in the user submitted sequence), (cause frameshift) agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactcgtgagggccgagttcaccatctccagagacaacgccaagaacacgctatatcttcaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18480 JY8QFUQ01BO776 productive Homsap IGHV3-9*01 F 891 90.32 196/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD3-22*01 F 2 8 8 26 8.8.26 [1.17.38.11] CVKDHGVTYFYDSVGYVSGAYNYAMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcacctttgatgattttggcatgcactgggtccggcaagttccagggaagggcccggagtgggtcgcaggtattagttggaatggtggacatatggactatgcggactctgtgaagggccgattcaccgtgtcccgagacaacgccgagaattccctgtatctgcaaatgaacagtctgacacctgaagacacggccctgtattactgtgtaaaagaccatggcgtcacttacttttatgacagtgttggttatgtctccggggcgtacaactacgcaatggacgtctggggccaggggacgacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18481 JY8QFUQ01B35EB productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 918 91.71 199/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKAGRGLIRPNNWFDPW in-frame + ctctggatttaccttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcggggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18482 JY8QFUQ01DD88U productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 950 93.12 203/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcatcttcagcaaccttgcaatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +18483 JY8QFUQ01ASA25 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 440 78.87 112/142 nt 8 8 X 8.8.X [1.17.13.X] null + No rearrangement found Low V-REGION identity (78,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctacgtggtcgtcgcatgcctggtccagggcttcttc +18484 JY8QFUQ01BPAXT unknown (see comment) Homsap IGHV3-11*01 F (see comment) 468 68.2 148/217 nt 67.74 147/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (68,20% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); ctctggattcaccttcaGgtgactactacatgagctggatccgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcatggtatacctggcagactccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18485 JY8QFUQ01BGNSE productive (see comment) Homsap IGHV4-55*03 P (see comment) 613 75.69 165/218 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [2.17.38.11] CARESRNSFGGPTGLDSW in-frame + however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01BGNSE ; 9 AA in Homsap_IGHV4-55*03), and low V-REGION identity (75,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gtctctgttgacgccataagcgacctcggttatttctgggcctgggtccgccagcccgccgcgaagggactggagtggatcggacatgcccttggtgatggatataccgaatacaaccccgccctagagagtcgaatcaccgtgtcagtggacaagtccaagaaccagttttccctgacgttggagtccgtgaccgccgcagacacggccacttatttctgtgcgagggaaagtcggaattcatttggcgggccgacaggccttgattcctggggccagggaattgtggtcatcgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcatcgcctgcctggtccagggcttct +18486 JY8QFUQ01ADG23 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F (see comment) 790 84.23 187/222 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-9*01 F 2 10 7 11 10.7.11 [2.17.38.11] CARILDGYFFDPW in-frame - Low V-REGION identity (84,23% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gtctctggtggctccatcgacactcaaaattactactggggctggattcgccagcccccagggacgggactggagtgggttggcagtgtccgctatggcgagagcacctattacaacccgaccctcaaaagtcgactcaccatatccatagacacgtccaggagccagttatccctgagactgagttctgtcaccgccgccgacacggcagtttactactgtgcgaggatcttggatggttacttcttcgacccctggggccagggaacccacgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18487 JY8QFUQ01C9T87 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 905 90.83 198/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18488 JY8QFUQ01BURMR productive Homsap IGHV3-11*01 F (see comment) 756 83.41 181/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD2-8*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGRGRTNSPVDLW in-frame + Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccctcagtgactacagtatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatacatcagccgaagtggaagtaatgtggaaactgcggactctgtgaggggccgattcaccgcctccagggacaccgccaataattcactgtttctgcggatgaatagcctgacagtcgaggacacggccctctattactgtgcgagaggtagggggcgcactaatagtccagttgacctctggggccagggaacccaggtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctcctgcagcacccagccagatgggaacgtggtcatcgcctgcctagtccagggcttcttccccca +18489 JY8QFUQ01CFZQK productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'A' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcaatagaaAactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18490 JY8QFUQ01CG395 productive (see comment) Homsap IGHV2-5*02 F, or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F 820 86.3 189/219 nt 85.39 187/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 3 10 7 11 10.7.11 [1.17.38.11] CAHFGPQEHFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'G' (1 nucleotides at position 191 to 191 in the user submitted sequence), (cause frameshift); tctggattctcactcagcaccaatggaatgggtgtgggttggatccgccagTcccccgggagaggccccagactggcccgctctcatttattgggatgatgataagcgataccggccatccctagagagtagactcaccatcaccaaggacatctccacaaaccaggtggtccttagaatgaccgacatgGggccctgcagacacagccacatatttctgtgcacactttggaccacaggagcacttcgacttttggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18491 JY8QFUQ01CZO1G productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*03 F or Homsap IGHV4-59*07 F 472 93.52 101/108 nt 92.59 100/108 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 X 15 8.X.15 [1.15.11.11] CAKNNNDFGDYDWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 106 nucleotides (from position 76 in the user submitted sequence), (cause frameshift) ctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttaaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18492 JY8QFUQ01BGUDP No results +18493 JY8QFUQ01BDVNF productive (see comment) Homsap IGHV4-61*02 F 895 90.74 196/216 nt 87.04 188/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 7 13 8.7.13 [2.16.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'CTGGTT' (6 nucleotides at position 25 to 30 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'AC' (2 nucleotides at position 120 to 121 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 133 to 133 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 222 to 222 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) tgtctccggtggctGccatcagtaCTGGTTattactactGggagctggatccggcagtccgccgggaagggactgaatggattgggcgcatgtctgccagagggggAcagcaactacaaACcccctccctccCagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtaCtttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18494 JY8QFUQ01CNCM5 productive (see comment) Homsap IGHV2-5*02 F 1012 90.57 221/244 nt 88.93 217/244 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 7 18 10.7.18 [9.17.38.11] CAHNSLYDRNGYYLTYFDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 27 of V-REGION: 'TG' (2 nucleotides at position 29 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 155 to 155 in the user submitted sequence), (cause frameshift); aaccctcacactgacctgcaacctctctTGggggtctcactcagcagtcgtggantgggtgtgggctggatccgtcaggccccaggaAaaggccctggagtggcttgccctcattgaCttgggatgatgacaagcgctatagtccatctctaaaCggggaggctcaccatcaccagggacacctccacaggccaggtggtcctcacaatgaccaacatgcaccctgtggacacagccacatattactgtgcacacaacagtctctatgataggaatggctattatttgacgtactttgatcactggggccagggagccctggtccccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18495 JY8QFUQ01B289X productive (see comment) Homsap IGHV3-7*03 F 822 87.38 187/214 nt 86.92 186/214 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [0.17.38.11] CTRRGFMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); cggattcacttttagtgactattggatgagttgggtccgccaggctccagGggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18496 JY8QFUQ01CU9FN productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +18497 JY8QFUQ01CJDBG productive Homsap IGHV3-66*02 F 840 88.32 189/214 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-8*01 F 3 8 7 11 8.7.11 [1.17.38.11] CASHLMVYALDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccgtcagtggcaagtacatgagctgggtccgccaggctccagggcagggactggagtgggtctcagttatctatagtactggtagtacatactacgcagattccgtgaaagggcggttcaccatctccagagacagttccaacaacactctatatcttcaaatttacggcctgagagctgacgacacggctacttactactgtgcgagtcacttaatggtgtatgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18498 JY8QFUQ01A4CKC productive (see comment) Homsap IGHV4-61*01 F 1100 100.0 221/221 nt 99.1 219/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcccccagggaagggactggagtggattggGgtatatctattacagtgGggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccagaaccggtgacggtgtcgtggaactcag +18499 JY8QFUQ01BROL6 No results +18500 JY8QFUQ01B2D9Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18501 JY8QFUQ01A9JOS productive Homsap IGHV3-11*01 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD1-26*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARDGDDYRSYYYGMDVW in-frame + ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcatggtatacctggcagactctgtgaagggccgattcatcatctccagggacaacggcgagaactcactgtatcttcaaatgaacagcctgagagccgaagacacggccgtgtattactgtgcgagagatggggacgactacaggtcgtactactatggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18502 JY8QFUQ01DHHR1 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 71 of V-REGION: 'C' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccCgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18503 JY8QFUQ01BHY4J unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 472 71.07 140/197 nt 8 7 X 8.7.X [1.17.32.X] null + No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BHY4J ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (71,07% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18504 JY8QFUQ01CUS2N productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt 93.78 211/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGXYYDSGGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctagcagcagtgttgTtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtnattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagcccagatgggaacgtggtctcgcctgcctggtccagggcttcttcccc +18505 JY8QFUQ01B33G7 No results +18506 JY8QFUQ01CSANS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 913 91.2 197/216 nt 90.28 195/216 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.37.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); in FR3-IMGT, from codon 94 of V-REGION: 1 nucleotides (from position 185 in the user submitted sequence), (cause frameshift) ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18507 JY8QFUQ01CDSSD productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 949 93.52 202/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctggattcacctttggttattGatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18508 JY8QFUQ01BVHZS productive (see comment) Homsap IGHV3-11*01 F (see comment) 694 79.91 175/219 nt 79.45 174/219 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-25*01 F 2 8 8 11 8.8.11 [2.17.38.11] CVRDRSRGIADPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); acgtctggattcaccttcactgactattggatgagttgggtgcgcctgAgccccagggaagggtctagaatgggtttcgttcataagtggaagtggcaatagtgtctggtatgcagactctgtgaagggccgattcattatctccagagacaacgccaaaaatttagtctttttggacatgaacagcctgagagtcgaggactcggccatgtattattgtgtgagagaccgcagcaggggaatagcagatccttggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18509 JY8QFUQ01CBMMN productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcg +18510 JY8QFUQ01ANRK5 productive Homsap IGHV3-7*01 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - ggctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18511 JY8QFUQ01AQ2VK productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ1*01 F 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKDHKSGWSLQDW in-frame + ctctggattcacctttaatatgtattggatgtactgggtccgccaggctccagggaaggggctggagtgggtggccaagataggcctagatggaagtcaaaaatactatgtggactctgtgaagggccgcttgaccatctccagagacaacgccaagaactcactatatctccaaatgaatagcctgagagccgaggacacgggtgtatactactgtgcgaaggatcataaaagtggctggagcctccaggattggggccagggcaccctggtcaccgtctcctcggcctccaccaagggcccatcggtcttcccccgtggcgccctgctccaggagcactccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18512 JY8QFUQ01C8FEX productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame - gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctattcggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18513 JY8QFUQ01BRVR1 unproductive (see comment) Homsap IGHV3-48*01 F 1071 99.54 216/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + stop codons ctctggattcaccttcagtagctatagcatgaactgagtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18514 JY8QFUQ01BX1X7 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 825 86.36 190/220 nt 85.0 187/220 nt Homsap IGHJ6*02 F 187 79.66 47/59 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [2.17.38.11] CARRDSDFRMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 181 to 181 in the user submitted sequence), (cause frameshift); ggtgtctggatatgactttagcagAattttggatcgcctgggtgcgccagatgcccgggaAaaggcctggagtggattggaatcatctatcctagtgactctgatacgagatacagtcccaccttccaaggccaggtcattatctcagccgacaagtccctcagtaccgcctacctacttTtttagcagtctgagggcctcggacaccgccatgtatttttgtgcgagacgtgattccgacttccgtatggacgtctggggccaggggaccacggtcaccgtgtctccaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18515 JY8QFUQ01AZPOK productive (see comment) Homsap IGHV3-66*02 F 898 91.55 195/213 nt 90.61 193/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.16.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcagtagcagcttcatgacttgggtccgccagctccaggaaggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18516 JY8QFUQ01BZ9RI productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 935 91.07 204/224 nt Homsap IGHJ4*02 F 184 90.91 40/44 nt 8 10 6 8.10.6 [1.17.38.11] CTTESAYW in-frame + tctctgcattcactttcagtaatgcctggatgacctgggtccgccaggctccagggaaggggctggagtggcttggccgtattaaaaggaaagttgatggtgagacaacagactacgctgcatccgtgaagggcagattcaccatctggagagatgactcaaaaaacactctatatctgcaaatgaacagcctggaacccgaggacacagccgtatattattgtaccactgaatctgcctattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18517 JY8QFUQ01C3KOZ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 856 88.13 193/219 nt 87.67 192/219 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [2.17.38.11] CMNEFGYCSGGG# out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); ggctctggattcacttttagcagccatatgatgacttgggtccgccaggctccagggaaggGggctggaatgggtcgcaagtattcgtgccagtggtggtaggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgttgtatttgcaaatgtacagtctgagagtcgaggacacggccttatattattgtatgaacgaattcggatactgtagtggtgggggggggccagggagcccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag +18518 JY8QFUQ01ADK2S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.99 194/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +18519 JY8QFUQ01DHQO3 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +18520 JY8QFUQ01DMU8Z productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18521 JY8QFUQ01CU00E unproductive Homsap IGHV3-48*01 F 954 93.55 203/217 nt Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDSRHSASGSYSDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactgggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18522 JY8QFUQ01B7RCO unknown (see comment) Homsap IGHV2-26*01 F (see comment) 792 80.33 196/244 nt 79.51 194/244 nt 10 7 X 10.7.X [9.17.38.X] null + No rearrangement found stop codons Low V-REGION identity (80,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR1-IMGT at codon 25 of V-REGION: 'CTCTGAG' (7 nucleotides at position 25 to 31 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcatcgtCTCTGAGctctgagttctcactcaacaatgctagaaagggtgtgagctggatccgtcagcCccccagggaaggccctggagtggcttgcacacattttttcgaatgacgaaaagtcctacaacacatctctgaagaccaggctcaccatctccagggacacctccaaaagccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +18523 JY8QFUQ01AXFJF No results +18524 JY8QFUQ01CZG88 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 880 90.61 193/213 nt 89.67 191/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 6 8 12 6.8.12 [1.17.38.11] CVRDGQRGYDNDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 5 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) gccctggattcaacaaaatatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaaActattagtggtagtggtggtaggacatactacgcagactccgtgaagggccgattcaccatctccagagacaatgccaggaactcactttttctgcaaatggacagcctgagagccgaagacacggctgtttattattgtgtgagagatgggcaaaggggctacgataatgactgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18525 JY8QFUQ01AGZLZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18526 JY8QFUQ01BQHSW unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGS## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtgggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa +18527 JY8QFUQ01CD7C8 productive Homsap IGHV3-7*01 F 912 92.06 197/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [0.17.38.11] CVRGRDGVNFGEMDYW in-frame - tgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18528 JY8QFUQ01BJ2NQ productive (see comment) Homsap IGHV3-72*01 F 948 91.93 205/223 nt 91.03 203/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GAA' (3 nucleotides at position 57 to 59 in the user submitted sequence), (do not cause frameshift); ctctggattcaccttaagtgatcactacatggGactgggtccgccaggctccaaggGAAagggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18529 JY8QFUQ01A0N2L unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGGW*R##LDYW out-of-frame - stop codons ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagccacccccaagatgggaacgtggttgtcgcatgcctggtccagggcttcttccccca +18530 JY8QFUQ01A4H4X unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 817 85.59 190/222 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD3-22*01 F 3 10 7 X 10.7.X [2.17.38.11] CVRLSDYYDTSGYAES## out-of-frame - gtctctggtgactccatcactaatagtcgttacttctgggcctggatccgtcagccccacgggaagggactggagtggattgggagcatctattacactgcgcaaaccaactccaacccgtccctcaagaatcgagtctccatatccatagacacgtccaagaatcagttcttcctgagtctcacctctgtgaccgccgcagattcggctgtgtattattgtgtgagactgagcgattattatgatactagtggttatgcggaatcctgggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18531 JY8QFUQ01ALZSP productive (see comment) Homsap IGHV3-9*01 F (see comment) 784 84.47 185/219 nt 83.56 183/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [2.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); gcctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggaGgtgggtcgcgggcaGtcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18532 JY8QFUQ01BITA5 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame - ctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18533 JY8QFUQ01CS3HY productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 992 94.57 209/221 nt 94.12 208/221 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.37.11] CTTGGGTNYYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 160 in the user submitted sequence), (cause frameshift) tctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18534 JY8QFUQ01DMKS5 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 853 89.2 190/213 nt 88.26 188/213 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [0.17.38.11] CTRDIGGRYSYW in-frame - stop codons in FR2-IMGT at codon 47 of V-REGION: 'GG' (2 nucleotides at position 51 to 52 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) cggattcaccttagtagtttctggatgcactgggtccgccaagttccaggGGgagggaactggtgtgagtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18535 JY8QFUQ01CBN73 productive (see comment) Homsap IGHV3-72*01 F (see comment) 804 84.0 189/225 nt 82.67 186/225 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-7*01 F 1 8 10 18 8.10.18 [2.17.38.11] CARGITGTTPPYYYYGMDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GGAAA' (5 nucleotides at position 59 to 63 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'GGTTCGGCA' (9 nucleotides at position 80 to 88 in the user submitted sequence), (do not cause frameshift); gtcgtctggatcaccttcagngaccactacatgGgactgggtccgccagcccccaaggGGAAAaggggnttggaggtggGGTTCGGCAccggtagtaggaaaacaaaagctggcagttacaccacagtatacgccgcgtctgtgaaaggcagattcagcgtctctagagatgattcccagaagtcactgtatctgcaaatgaacggcctgaaaaccgaggacacggccgtgtattattgtgctagagggataactggaactacgccgccctattactattacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18536 JY8QFUQ01ASRCX No results +18537 JY8QFUQ01AF07V productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18538 JY8QFUQ01CKFL6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18539 JY8QFUQ01BIK4E productive (see comment) Homsap IGHV3-48*01 F 894 91.12 195/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.16.38.11] CAKGHSTGSWLIDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 2 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagttataccatgaactgggcccgccaggctccagggagggcgtggagtggtgcattcatcggcagtacaactgataccgtatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccgagaactcactgtttctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgaaagggcattctactggcagctggttgattgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18540 JY8QFUQ01DCQ77 No results +18541 JY8QFUQ01CZ00U productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgcacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +18542 JY8QFUQ01DEK3I productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttataGgcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18543 JY8QFUQ01BQSL5 productive Homsap IGHV3-48*01 F 860 88.53 193/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame - tctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggagccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18544 JY8QFUQ01A1Q3N productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 797 85.32 186/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [1.17.38.11] CVKDRDFLWGSYRLQLESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattcacctttagtagctatggcatgagttgggtccgccagtctccaaataagggactggagtgggtcgcaggcattagtgcaaatggtggcagtataaattatctggacgccgtgaagggccggtttatcatctctagagacaattccaagaacacgttgtatctgcaaatggacagcctgacagtcgaggacacggccgtttattactgtgtgaaagatcgtgattttctttgggggagctatcgtcttcaacttgaatcttggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +18545 JY8QFUQ01ADAT4 productive Homsap IGHV2-5*02 F, or Homsap IGHV2-5*04 F 972 88.93 217/244 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD2-2*01 F 2 10 7 13 10.7.13 [9.17.38.11] CARKYGSSTNGFDPW in-frame + gaccctcacgctgacctgcacgttctctggattctcactcaacacacagggaatgggcgtggactggatccgtcagcccccaggaaaggccctagagtggctaggcctcatttactgggatgatgatacgcgctacagcccatctctgaggaacaggctcagcatcaccaaggacacttccaaaaaccaggtggtcctgacactgaccaacgtggacgctatggacacaggcacatattattgtgcgcgcaaatatggcagcagtacgaacggattcgacccctggggccagggactcctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttnttcccccc +18546 JY8QFUQ01ARA3B productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactc +18547 JY8QFUQ01B1B77 productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGKGLLSRFDHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtaagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcatggaactca +18548 JY8QFUQ01CCP6E productive (see comment) Homsap IGHV4-61*02 F 875 88.69 196/221 nt 88.24 195/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); tctctggtggccCccatcagcagcagcacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttcccc +18549 JY8QFUQ01CIOCG productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt 93.61 205/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [2.16.38.11] CARDTLEVVSNMDDAFDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) agcctctggattcaccttcagtcgttGatagcatgaactgggtccgccaggctcgagggaagggcttgagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18550 JY8QFUQ01BSC6G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame + cctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18551 JY8QFUQ01BV8Y2 productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18552 JY8QFUQ01C060D unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 940 93.06 201/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + stop codons tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgtaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18553 JY8QFUQ01CCQXW productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtacttactactggacatggatccgccagcAccccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18554 JY8QFUQ01AE5FV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - gcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18555 JY8QFUQ01DIZBB productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 896 90.37 197/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ggcctctggatcaccctttggttattGatggcatgactgggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18556 JY8QFUQ01COTUF unproductive Homsap IGHV3-48*02 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [0.17.38.11] CARDMIIFGEP#DNW out-of-frame - tggattcgccttcagtagttccagcatgaactgggtccgccagggtccagggaaggggctggagtggatttcacacattaggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttggggagcccttgacaactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18557 JY8QFUQ01BPLX0 No results +18558 JY8QFUQ01DJLNZ productive Homsap IGHV3-11*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame + cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgccatggcctggtccagggcttcttcccc +18559 JY8QFUQ01B4NSQ No results +18560 JY8QFUQ01BKVFD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18561 JY8QFUQ01CS6IW productive (see comment) Homsap IGHV3-48*01 F 928 91.78 201/219 nt 91.32 200/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CTRQTGNYYYFGVDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'A' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); gcctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggAaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18562 JY8QFUQ01AZI1W unproductive Homsap IGHV3-9*01 F 848 89.15 189/212 nt 88.68 188/212 nt Homsap IGHJ1*01 F (see comment) 80 61.54 32/52 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.36.11] CSKDRYHFDSSQHAMDVW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 82 of V-REGION: 6 nucleotides (from position 150 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttggtgactttgccatgcactgggtccgacaacctccagggaagggcctggagtgggtcgcgactattagttggaggaatattagtagaggctatgcggactctgtgaagggccgattcaccatctccagagacaagaactccctgtacttgcaaatgaacactctgagatcagaggacacggccttctattattgttcaaaagacaggtatcattttgatagtagtcagcacgctatggacgtctgggggccaagggacccccggtcaccgttttctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +18563 JY8QFUQ01DBASA unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 88 49.73 92/185 nt 8 7 X 8.7.X [1.17.28.X] null + No rearrangement found stop codons cctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa +18564 JY8QFUQ01BRZBI productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18565 JY8QFUQ01AIIJ3 No results +18566 JY8QFUQ01B9KPG No results +18567 JY8QFUQ01DMVKI productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1011 96.74 208/215 nt 94.88 204/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARGGGYYFVAIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'TG' (2 nucleotides at position 95 to 96 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'AC' (2 nucleotides at position 114 to 115 in the user submitted sequence), (cause frameshift); tctctggtggctGccatcagtagCttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaaanTGgggagcaccaactacaaACcccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18568 JY8QFUQ01DSZT6 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKK*GVGDG##WYFDFW out-of-frame + stop codons in CDR2-IMGT at codon 58 of V-REGION: 'ATG' (3 nucleotides at position 87 to 89 in the user submitted sequence), (do not cause frameshift); ctctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattactaATGgtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttatttctgtgcgaaaaaatagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18569 JY8QFUQ01DEOJZ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 758 82.81 183/221 nt 82.35 182/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); gtctctgtgactccatcagtagtGactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18570 JY8QFUQ01AYC76 productive Homsap IGHV3-NL1*01 F (see comment) 330 73.08 95/130 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 X 5 17 X.5.17 [X.X.38.11] CARDSVPRASEAAYHFDYW in-frame - Low V-REGION identity (73,08% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattctccttcagaagttactctttccactggggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18571 JY8QFUQ01BHAGC unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 134 63.29 50/79 nt 8 X X 8.X.X [1.17.X.X] null + No rearrangement found ctctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18572 JY8QFUQ01BB8RF unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1004 95.87 209/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPGGDCLL*WW*#CYDPW out-of-frame - stop codons cctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccagggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18573 JY8QFUQ01BKE2G unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ3*02 F 88 64.0 32/50 nt 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttaCctggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaagggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18574 JY8QFUQ01AH8RP No results +18575 JY8QFUQ01A4BLB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKYVEGWSYTGGYYNSYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); ttctggattcgcctttagccgttatgccatgacttgggtccgccagactccagggagggggctggagtgggtctcaggtctcagtggtagtggtgatagcacatactaCtcaaaactccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggaggggtggtcatatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18576 JY8QFUQ01ATLUC unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 730 79.91 183/229 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [5.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - stop codons Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggactccatttccagtacctagttaattgacttggggctgggtccgccancccccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18577 JY8QFUQ01A7PRV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18578 JY8QFUQ01CVGHI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-21*02 F 3 8 8 13 8.8.13 [1.17.38.11] CAKHRLVTSNHFASW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); cctctggattcaccGtttagcacctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtgatagcacaaactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaacaacacgctatatctgcagatgaacagcctgagagccgaggacccggccgtgtattactgtgcgaaacaccgtttggtgaccagcaaccactttgcctcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18579 JY8QFUQ01CVBL6 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1025 97.67 210/215 nt 96.28 207/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARGGGYYFVAIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'A' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagCttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaAaagtgggagcaccaactacaaccCcctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +18580 JY8QFUQ01CYCK8 productive (see comment) Homsap IGHV3-7*01 F 1000 95.43 209/219 nt 94.06 206/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.16.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 73 in the user submitted sequence), (cause frameshift) gggctctggattcagctttagttactattGggatgagctgggtccgccaggctccagggaaTggggctggagtggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18581 JY8QFUQ01CPAOQ productive (see comment) Homsap IGHV3-7*03 F 941 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-7*01 F 1 8 8 16 8.8.16 [1.17.38.11] CATARLGPGTSIYLTAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); cctctggattcacctttggtagctattggatgggcCtgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgcgagtcgaggacacgggcatttacttctgcgcgacagcccgtctcgggcctggaacttcgatttatctcacggcctactggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18582 JY8QFUQ01AIWG6 unknown (see comment) Homsap IGHV3-64*02 F, or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 99 52.59 71/135 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons tctctggattcagcttcagtgactatggcatgggctgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18583 JY8QFUQ01B26R3 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 857 89.2 190/213 nt 88.73 189/213 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift); tcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagGactccntgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgcgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +18584 JY8QFUQ01ATAYA No results +18585 JY8QFUQ01BBPPK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18586 JY8QFUQ01B92LW unproductive (see comment) Homsap IGHV3-7*01 F 955 93.15 204/219 nt Homsap IGHJ3*02 F 88 64.0 32/50 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [2.17.38.11] CVRRGW*RAD#DAFDIW out-of-frame - stop codons gcctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaaggggatggtagcgggcagatatgatgcttttgatatctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18587 JY8QFUQ01DQ5GC productive (see comment) Homsap IGHV3-66*02 F 876 90.19 193/214 nt 89.72 192/214 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD3-16*01 F 2 8 7 13 8.7.13 [1.16.38.11] CAALHDPPWGWLDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcagcgtcaacaacaactacatgaactgggtccgcctggctccagggaaggtctggagtgggtctcagttatttatagaggtggtaatacattctacacagactccgtgaagggccggttcaccatctccagagacatttccaagaacactttgtatcttcaaatgaacagtctgacaactgaggacacggctgtgtactattgtgcggccctccacgaccctccttggggttggctcgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18588 JY8QFUQ01B1SZE unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 386 84.91 90/106 nt 83.96 89/106 nt 8 8 X 8.8.X [1.16.1.X] null - No rearrangement found Low V-REGION identity (84,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 45 of V-REGION: 2 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) gctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggaggggggctggagtgggtctcagccattagtggcagtggtagtcggacatatt +18589 JY8QFUQ01CD2BO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 913 91.67 198/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 21 8.8.21 [1.17.38.11] CVRVGAPYYDFWSGYQTNWFDPW in-frame - tctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgcaagtactacttccatacattatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggcgccatattacgatttctggagtggctatcagactaactggttcgacccctggggccagggaactctggtcaccgttacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18590 JY8QFUQ01CFKOA No results +18591 JY8QFUQ01CKHQ3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18592 JY8QFUQ01CX8CY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18593 JY8QFUQ01CRD7Z productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaAaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18594 JY8QFUQ01DBZ9Q unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 3 10 7 X 10.7.X [1.17.38.11] CVRPDNYFGSGEC#WMDPW out-of-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcgggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18595 JY8QFUQ01AGER9 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18596 JY8QFUQ01CKS7U productive Homsap IGHV3-48*02 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARVENYSDSGGSFDYW in-frame - cctctggattcaccttcagtagctatagcatgaattgggtccgccaggctccagggaagggactggagtgggtttcatacattagtggaagtagtaataccatgtactacgcagactctgtgaagggccgattcaccatctccagagacaatgcccagaattcactacatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagtggaaaattactctgatagtggtggttcgtttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18597 JY8QFUQ01CLEF5 unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 1 10 9 X 10.9.X [1.17.38.11] CTRGSSRGGRYDENYYELDF## out-of-frame - tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18598 JY8QFUQ01AA38B productive Homsap IGHV3-30*04 F, or Homsap IGHV3-30*09 F or Homsap IGHV3-30-3*03 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARDRRPLREFDYW in-frame + ctctggattctccgtttccagctatgctctgcactgggtccgccagtctcccggcaaggggctggagtgggtggcggctatttcatatgatggaagtaaaatatattatgcagactccgtgaggggccgcttctccatctccagagacacttccaggaacactctgcatttgcaaatggacggcctgagagctgacgacacggctacatattactgtgcgagagacagacggccacttagggagtttgactattggggccagggaaccctggtcgccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccg +18599 JY8QFUQ01CAH1L productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18600 JY8QFUQ01CQL7O No results +18601 JY8QFUQ01BLCSS unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + stop codons ctctggattcaccttcagtagttataacatgcactgagtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18602 JY8QFUQ01B5BBS productive Homsap IGHV3-7*01 F 1022 96.79 211/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + cctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc +18603 JY8QFUQ01B1S6W productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD4-11*01 ORF 2 8 7 17 8.7.17 [1.17.38.11] CARVGRSVGYSDSGWFDPW in-frame + tctctggtggctccatgagtagttactactggaactggattcggcagcccccagggaagggactggagtggattgggtatatctattacactgggatcaccaactacaatccctccctcaagagtcgagtcaccatgtcaatagacacgtccaggaagcagttctccctgaccctgacctctgtgaccgctgcggacacggccgtctatttctgtgcgagagtcggccggagtgtgggctacagtgactctgggtggttcgacccctggggccagggaaccctggtaccgtctcctacccatcccgaccagccccaaggtcttcccgctgagccctctgcagcacccgagccagatgggaacgtggtcatcgcctgcctggtccagggccttcttcccccag +18604 JY8QFUQ01C6ZKX productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 858 89.25 191/214 nt 88.79 190/214 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctatggtgggtccttcagtacttactactggacatGggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18605 JY8QFUQ01CB4CV unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccaggggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttcccccca +18606 JY8QFUQ01B8ABJ productive Homsap IGHV1-2*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [0.17.38.11] CARGGTVTAGGPRIVFGYW in-frame + tggctacaccttcaccgactactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcaaccctgacggtggtagcacaaagtatgcacagaaatttcagggcagggtcgccgtgaccagggacacgtcaattagcacagcctacattgaggtgaccagactgacatctgacgacacggccgtgtattattgtgccagaggagggactgtgacagcaggtggtcctcgtattgtctttgggtactggggccagggaacgttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18607 JY8QFUQ01CRFE1 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 630 93.1 135/145 nt 92.41 134/145 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 7 16 8.7.16 [1.17.14.11] CARGPVGISESVNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 65 of V-REGION: 73 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagaggtccggttgggataagtgaaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18608 JY8QFUQ01CAWSO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttcccccca +18609 JY8QFUQ01CM1KM productive (see comment) Homsap IGHV3-23*05 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +18610 JY8QFUQ01AGBNN productive (see comment) Homsap IGHV3-48*01 F 985 95.37 206/216 nt 94.44 204/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); tctggtttcaccGttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaAaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18611 JY8QFUQ01BPY9Q unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1009 95.89 210/219 nt 94.98 208/219 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [2.17.38.11] CARDNYGDY## out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'CG' (2 nucleotides at position 95 to 96 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaagGgggctggtgtgggtctcacgtgttaatggtgatCGgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18612 JY8QFUQ01AJOX0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.74 200/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + cctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18613 JY8QFUQ01DCN0X unknown (see comment) Homsap IGHV3-72*01 F 106 53.44 70/131 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +18614 JY8QFUQ01B3UPR productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 805 85.71 186/217 nt 84.33 183/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'CA' (2 nucleotides at position 53 to 54 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) tccgggagttcaccttagtagtttctggGatncactggggtccgcaagttccCAaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +18615 JY8QFUQ01BNN3E productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1027 96.8 212/219 nt 96.35 211/219 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 164 81.63 40/49 nt Homsap IGHD2-21*02 F 3 8 8 7 8.8.7 [2.17.38.11] CARMTDDFW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); gtctctggattcaccttcagtagctataGgcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagcagtagcaccataaaatacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtgcgagaatgacagacgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +18616 JY8QFUQ01CZ0RM productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18617 JY8QFUQ01BUDBO No results +18618 JY8QFUQ01BBY90 No results +18619 JY8QFUQ01DROLK No results +18620 JY8QFUQ01ANFIE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.02 191/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKCKAPGKVDWFDPW in-frame - ctctggattcacctttagcggctatnccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctggtaaggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18621 JY8QFUQ01ANNVX unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLPFIVVVTGAFLGHFDY## out-of-frame + ttctggatacatctttaccaattactggctcggctgggtgcgccagatgcccggcaaaggcctggagtggatggggatcatctttcctgctgactctgatgcccgatacagcccgtccttccaaggccaggtcaccatctcaatcgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacgccgccatatattactgtgcgagactcccctttattgtggtggtgactggtgcgtttttgggacactttgactattggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18622 JY8QFUQ01ABD4U productive Homsap IGHV3-64*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + cctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18623 JY8QFUQ01CPF88 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18624 JY8QFUQ01DJ7CR No results +18625 JY8QFUQ01B37PC productive (see comment) Homsap IGHV4-61*02 F 994 95.83 207/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [2.17.38.11] CTNGGHYYGSEFDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'GCAGTG' (6 nucleotides at position 20 to 25 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); gtctctggtgactccatcaGCAGTGgcagttactactggagctggattcggcagcccgccgggaagggactggagtggattgggcgtttgcataccagtgggggcCaccgactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggccgtgtattactgtactaatggcgggcattactatggttcggagtttgactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18626 JY8QFUQ01BDXFT No results +18627 JY8QFUQ01AWE6F productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 833 87.16 190/218 nt 86.24 188/218 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARLRSFGDYPLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccGggggaagggactggtgtGgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +18628 JY8QFUQ01CNIOH productive (see comment) Homsap IGHV4-61*01 F (see comment) 767 83.26 184/221 nt 82.81 183/221 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); tgtctggtggctccgtcagcagtggaaAattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtccaaggactacttccccgaaccggtgacggtgtcgtggaactc +18629 JY8QFUQ01DXB5W No results +18630 JY8QFUQ01ARQX3 unproductive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAGAEAGL#DYW out-of-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcgggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccccttggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18631 JY8QFUQ01CDUAP productive (see comment) Homsap IGHV3-48*03 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) agcctctggattcaccttcagttcttatgccatgaactgggtccgctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18632 JY8QFUQ01CQJZD productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18633 JY8QFUQ01AQBPX unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +18634 JY8QFUQ01CTDAY No results +18635 JY8QFUQ01BNNYX productive (see comment) Homsap IGHV2-5*02 F 1116 95.49 233/244 nt 94.67 231/244 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 10 7 14 10.7.14 [9.17.38.11] CAHIRAELSTSCHAFW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 81 of V-REGION: 'G' (1 nucleotides at position 173 to 173 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 185 to 185 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccaggaaaggccctggagtggcttgcacttgtttattgggatgatgataagcgctacagctcatctctgaagagcagactcaccatcaccaagGgacacctccaaAaaaccaggtggtccttacaatgactaacatggaccctatggacacagccacatattactgtgcacacattagggcggaacttagtaccagctgccatgccttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +18636 JY8QFUQ01CA1TB unproductive Homsap IGHV3-48*02 F 904 91.2 197/216 nt 90.28 195/216 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [2.17.37.11] CARDHWDNNGYHWFD#PG out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 89 of V-REGION: 3 nucleotides (from position 172 in the user submitted sequence), (do not cause frameshift) gcctctggaAttcgccctcagtagttataccatgaactgggtccgccaggccccaggcaaggggctggagtgggtttcacacacaagtagcagcgttagcaacatgttctacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtatcaaatgaacagcctgagagacgaggacacggctgtatattactgtgcgagagatcattgggacaacaatggttatcactggttcgacccctggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccgaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18637 JY8QFUQ01BDV2Y productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*05 F 867 89.72 192/214 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [0.17.38.11] CARVGGDDDDGYYVGEDAMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tggatacaccttccccgaccactatgtacactgggtgcgacaggcccctggacaagggcttgagtggatgggacggatcagccctaacactggcggcgcacactatggacagaggtttcagggcagggtcaccatgaccagggacacgtccatcaccacagtctacatggaattgagcaggctgagtccggatgacacggccgtgtattattgtgcgagagttgggggagatgatgatgacggttactatgtcggggaggacgctatggacgtctggggccaggggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18638 JY8QFUQ01CSHAA unproductive Homsap IGHV4-4*07 F 905 92.82 194/209 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD3-22*01 F 3 7 7 X 7.7.X [X.17.38.11] CARGKDYYDSTGSLEDGLDI## out-of-frame + gtggctccctcagtacttactactggaactgggtccggcagcccgccgggaagggactggagtggattgggcgtaaatatcccagtggggacaccaactataatccctccctcaaaagtcgagtcaccatgtcactagacacgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagagggaaggattactatgatagtactggttccctcgaggatggtcttgatatctgggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18639 JY8QFUQ01AVJRE productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18640 JY8QFUQ01CABL5 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 962 94.42 203/215 nt 93.49 201/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 3 8 7 17 8.7.17 [1.17.38.11] CARGRMVRGVTLIWWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); tgtctggtgggtccttcagtacttactactgGgacctggatccgccagcCccccagggaaggggctggagtggattggggaaatcagtcatagtggaagcaccaactacaacccgtccctcaagagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgaaactgatctctgttatcgccgcggacacggctgtgtattattgtgcgagaggcaggatggttcggggagttaccctgatctggtggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18641 JY8QFUQ01CJESL No results +18642 JY8QFUQ01CF5D6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [2.17.38.11] CTREVGATDYW in-frame - gcctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18643 JY8QFUQ01CLSXJ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 302 96.88 62/64 nt 8 X X 8.X.X [1.12.X.X] null - No rearrangement found tctggattcaccttcagcagctatagaatgaactgggtccgccaggctccagggaaggggctgg +18644 JY8QFUQ01C2508 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 113 50.48 105/208 nt 8 8 X 8.8.X [1.17.35.X] null - No rearrangement found tctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18645 JY8QFUQ01CXQH0 productive Homsap IGHV3-66*02 F 953 93.95 202/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame + cctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18646 JY8QFUQ01CGT1P productive Homsap IGHV3-23*03 F (see comment) 813 86.92 186/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 2 8 7 11 8.7.11 [1.17.38.11] CARDRQSWGIDSW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CGT1P ; 8 AA in Homsap_IGHV3-23*03) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggtgacacatactacgcagactccgtgaagggccgattcaccatctccagagacaacgccaagaatacactttttcttcaaatgacttccctgagagtcgaagatacggccatttattactgtgcgagagatcgtcagagctgggggattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18647 JY8QFUQ01DCUSM productive (see comment) Homsap IGHV3-66*02 F 898 91.55 195/213 nt 91.08 194/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.16.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) ctctggattcaccgtcagtagcagcttcatgacttgggtccgccagctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18648 JY8QFUQ01CIXUH productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18649 JY8QFUQ01CJ2Q1 unknown (see comment) Homsap IGHV3-7*01 F 909 91.24 198/217 nt 90.78 197/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggGccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctcccccatttacggtgactactgggaaggacgcctactggggcccagggcaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa +18650 JY8QFUQ01CIGXV productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18651 JY8QFUQ01BR5P2 productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYYYYDTNGDYW in-frame - ctctggatttacctttacaaattattggatgagctgggtccgccaggctccagggagggggctggagtgggtggccagcgtaaaacaagatggaggtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggtcctactattattatgatactaatggcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18652 JY8QFUQ01B8LO4 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18653 JY8QFUQ01AV5VY productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*03 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 914 91.28 199/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 7 16 8.7.16 [2.17.38.11] CARDEIPWDTIEYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) gcctctggattcaccGttcactacatattccatgcactgggtccgccaAggctccaggcaaggggctagaatgggtggcagttatatcatatgatgggaaaaaaaatcttatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtacctgcaaatggacagcctgaggcctgaagacacggctgtgtattactgtgccagagatgagatcccttgggatacaatagagtactactttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18654 JY8QFUQ01AMACY No results +18655 JY8QFUQ01DW0ED unknown (see comment) Homsap IGHV3-7*01 F (see comment) 756 82.95 180/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggagtcacctttagtgactattggatgagctggatccgccaggctccagggaaggggccggagtgggtggccaacatagagcaagatgggagtgagataaattatgtggactctgtgaagggccgattcaccatctccagagacaacaccgagaatgcactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18656 JY8QFUQ01B5F3C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-10*01 F 3 8 8 14 8.8.14 [1.17.38.11] CASDMIRGEYDAFDIW in-frame + ctctgaattcacctttaacaattctgtcatggtctgggtccgccaggctccagggaaggggctggagtgggtctcagaaattagtggtagtggtactagcacatattacgcagactccgtgaagggccggttcaccatttccagagacaattccaagaacacactttttctgcaaatgaacagcctgagagtcgacgacacggccgtatattattgtgcgagtgatatgattcggggagaatatgatgcttttgatatctggggccaagggacaacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggttaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18657 JY8QFUQ01AL9MI productive Homsap IGHV3-11*01 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVRDGARRTNQWLAHDFW in-frame - Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagctttaatgccttctatatgggttgggtccgccaggctccaggaaaggggctggagtggatttcgtacattaactctggtggtagtgacacatattacgcagactctgtgaagggccgattcaccatctccagggacaacgcctgggacacaatgtacttggaaatgaacagcctgagagccgaagacacggccgtctactattgtgtgagagatggcgctagaaggacgaatcagtggctggcccatgacttctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18658 JY8QFUQ01DFAF1 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaAaggggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18659 JY8QFUQ01BEQ30 No results +18660 JY8QFUQ01DJCEH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca +18661 JY8QFUQ01CAVKW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVKEDHDSGLRVLLEW in-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18662 JY8QFUQ01AQBZ9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18663 JY8QFUQ01APJHU productive (see comment) Homsap IGHV3-7*03 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tccggattcacttttagtgactattggatgagttgggtccgccaggctccagGggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18664 JY8QFUQ01AJG2F productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18665 JY8QFUQ01B1MCX unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18666 JY8QFUQ01BVL07 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 838 87.21 191/219 nt 86.3 189/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); gcctctggattcacAttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgttccagtggtgataggacacactatgcagactccgtgaaggGgccgcttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +18667 JY8QFUQ01B94C3 No results +18668 JY8QFUQ01BO8WN productive (see comment) Homsap IGHV4-61*02 F 830 86.43 191/221 nt 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARDTGQTYGRGPLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); tctctggtgcctccataaataggggtaattattactgGgaactggatccggcagcccgccgGggaagggcctggaatggattggccgaatctatacaagtgggagcaccatctacaacccctccctcgggggtcgagtcaccatgactgtagacccgtccgagaatcagttcttcctgagactgagttctgtgaccgccgcagacacggccgtttatttttgtgcgagagacactggacaaacctacggtcggggccctttggactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18669 JY8QFUQ01DA68T productive Homsap IGHV3-48*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGNYYYFGMDVW in-frame + ctctggattcctcttcagtagctttaacatgaactgggtccgccaggttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccatctactactgtgcgagacaaactgggaattattattacttcggtatggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccccca +18670 JY8QFUQ01CZEBO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKKYHYGSGSYLYCFDYW in-frame - gcctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtggtgatgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactgctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18671 JY8QFUQ01CN1OP productive Homsap IGHV3-11*01 F 946 92.69 203/219 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD2-21*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARGKMVSTGMDVW in-frame - Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) ggctctggattcacgtttagtgactactacatgacctggattcgtcaggctccagggaagggcctggagtgggttacatatattagtagtagtggtggtaacacacattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaacgcactgtatctgcaaatgaacagcctgagggccgaggacacggccgtgtattactgtgcgcgagggaagatggtgagcaccggtatggacgtctggggccaagggaccacggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18672 JY8QFUQ01DO5GE unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 761 83.03 181/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18673 JY8QFUQ01DFY56 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcaaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18674 JY8QFUQ01B43L0 productive Homsap IGHV3-9*01 F 891 90.32 196/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRQAYYHDSSAYFFSRYWYFDLW in-frame - ctctggattcacttttgatgactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacgccaagaagtccctgtttctgcaaattaaaagtctgagagttgaggacacggccttatattattgtgtgaggcaagcgtattaccatgatagcagtgcttacttcttctcccgctactggtacttcgatctctggggccgtggcaccccggtcactgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18675 JY8QFUQ01CV708 productive Homsap IGHV4-61*02 F (see comment) 578 73.76 163/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERRDSIRGATGLDYW in-frame + Low V-REGION identity (73,76% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtagccccatcagcgactccaattatttctggacctgggtccggcagcccgccgggaaggaatttgagtggatcggacatgttctcaataatgcatatagcgagtataatccctccctagggagtcgcgtcaccgtgtcaatggacaagtccaagaatcagttttccctgaagttggagtctctgaccgccgcagacacggccacttatttttgtgcgagagagcgtcgggattcgattcgcggagcgacaggccttgactactggggccagggaattttggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18676 JY8QFUQ01BE1Z2 unproductive Homsap IGHV3-11*01 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CARYRGSYYDYGGVDV## out-of-frame - Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggcttcagattccgtgactactacatgacgtgggtccgccaggctccagggaagggtcttgagtggctttcctccatcagcagcggtagtaataccatccactactcagactcggtgaggggccgcttcaccatctccagggacaacaccaggaactcagtggatctgcaaatgaatagtctgagagccgaagacacggccgtctattattgtgcgaggtacagaggcagttactacgactatggcggtgtggacgtctgggggccaagggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +18677 JY8QFUQ01CA0F8 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F (see comment) 644 77.06 168/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (77,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctcgggattcaacttcaagtccaacaccatgaattgggtccgccaggctccagggaaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18678 JY8QFUQ01A6L6Y No results +18679 JY8QFUQ01A97F7 unknown (see comment) Homsap IGHV4-61*02 F 884 89.14 197/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc +18680 JY8QFUQ01BG2T4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 897 90.0 198/220 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - agcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18681 JY8QFUQ01BFYLR unproductive Homsap IGHV3-7*02 F 917 92.09 198/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 7 8 X 7.8.X [1.16.38.11] CARDQVTEDY# out-of-frame + in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 33 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactgggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18682 JY8QFUQ01B5ZV4 productive Homsap IGHV4-61*02 F 956 92.76 205/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame + tctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18683 JY8QFUQ01A13UB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 845 88.37 190/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'CC' (2 nucleotides at position 27 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'CG' (2 nucleotides at position 93 to 94 in the user submitted sequence), (cause frameshift); ctggattcaccttcgggaacctatggCCatgacgtgggtccgcctgactcctgggaaagggctggagtggGgtttcacgtgttaatggtgatCGgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18684 JY8QFUQ01A4E26 No results +18685 JY8QFUQ01BSZDV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 942 92.27 203/220 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - agcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccgagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18686 JY8QFUQ01A5V4C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcacttcccccgaaccggtgacggtgtgcgtggaactca +18687 JY8QFUQ01BA01C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18688 JY8QFUQ01B0A6E productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18689 JY8QFUQ01B6G3Q productive Homsap IGHV4-39*02 F (see comment) 776 83.71 185/221 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD2-15*01 F 2 10 7 19 10.7.19 [1.17.38.11] CARHLTNSDVVHHFYSGVDVW in-frame + Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgcctccatcagtaatgataattatttctgggcctgggtccgccagtccccagggaagggtctgcagtggattggcagtatgtattatagtgggggcaccttttacgacccgtccctcaagggtcgaatcaagttgtccgttgacgtgtcgaagagccacttcctcctgaacctgacctctgcgaccgccgcagacacggctgtctattactgtgcgaggcatttgaccaactcagatgtggtccatcacttctactccggagtagacgtctggggcctcgggaccacggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18690 JY8QFUQ01C4V01 No results +18691 JY8QFUQ01AO121 productive (see comment) Homsap IGHV4-61*07 F (see comment) 1023 98.58 208/211 nt 98.1 207/211 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [2.17.37.11] CASANYDYVWGSYRYDYW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (8 AA in JY8QFUQ01AO121 ; 10 AA in Homsap_IGHV4-61*07) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 75 of V-REGION: 2 nucleotides (from position 131 in the user submitted sequence), (cause frameshift) tgtctcctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18692 JY8QFUQ01BBEKI unproductive Homsap IGHV3-48*03 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ5*01 F (see comment) 111 68.63 35/51 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.16.38.11] CARDKGWSGYGMDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 41 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagttcttatgccatgaactgggtcgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +18693 JY8QFUQ01ADMT0 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1075 100.0 216/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-2*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKPSSTSSRARTSHFDYW in-frame - tctggattcaccttcagtagctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgaagcctagtagtaccagctcccgcgctcgcacctctcactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18694 JY8QFUQ01BTW17 unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18695 JY8QFUQ01B0L8O unproductive Homsap IGHV3-13*01 F 971 94.88 204/215 nt 94.42 203/215 nt Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD1-1*01 F 2 8 7 X 8.7.X [1.17.38.11] CARGSSKAYNWF#PW out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); cctctggattcacgttcagtaattacgacatgcactgggtccgccAaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgaccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaactc +18696 JY8QFUQ01AOKGG productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18697 JY8QFUQ01DJIVW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKDLGLVGATGLDYW in-frame + ctctggattcacctttcgcagatatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattaataatagtggtggtagcacatactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcaactgagcagcctgagagccgaggacacggccatgtatttctgtgtgaaagatctgggactagtgggcgctactgggctggactactggggccagggaacccgggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18698 JY8QFUQ01AVEUZ productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-7*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDRNYAFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagcagcGtttagtatgaactgggtccgccaggctccagggaagggactggagtggctttcatacattagtaatactggtagtaacaaatactacgcagactctgtgaagggccgattcaccatctccagagacgatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgtgcgagagatcggaactacgctttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18699 JY8QFUQ01C4CCO No results +18700 JY8QFUQ01CC96N productive Homsap IGHV3-33*05 F (see comment) 752 83.03 181/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18701 JY8QFUQ01BG9LH productive Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + cctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcccatgctggtccaggggcttcttccccctag +18702 JY8QFUQ01AZ9YI productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18703 JY8QFUQ01B6S4O productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggGggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18704 JY8QFUQ01C3IW2 No results +18705 JY8QFUQ01B7TT3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CAKVRNSGSVWEGFSFDYW in-frame + cctctggattcatcttcagcaaccatggcatgagttgggtccgccaggctccagggaaggggctggagtgggtctcaaacattgctggaagtggtggcagtatatataacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacaccctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattattgtgcgaaagtgaggaatagcggtagtgtctgggaaggattctcctttgactattggggccagggagtcctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18706 JY8QFUQ01AJVDN productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18707 JY8QFUQ01BLGCA productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 962 94.42 203/215 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD4-17*01 F 3 8 7 16 8.7.16 [1.17.38.11] CARGSVTTWRRENWFDPW in-frame + tctctggtggctccatcagtacttattactggaactggatccggcagcccccagggaagggactggagtggattgggtatatccataacagtgggagtagcaactacaacccctccctcaagagtcgagtcaacatatctgtagacgcgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtttattactgtgcgagaggttcggtgactacgtggagacgggagaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18708 JY8QFUQ01DBBP4 productive Homsap IGHV3-23*05 F (see comment) 443 82.44 108/131 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 X 5 16 X.5.16 [X.X.38.11] CVRYDYSRLHRSNYFGPW in-frame - Low V-REGION identity (82,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggattcaccttcatcagttatgactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18709 JY8QFUQ01CGYBO unproductive Homsap IGHV4-61*02 F 898 89.64 199/222 nt 88.74 197/222 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 10 7 X 10.7.X [2.17.38.11] CARDPQGFICSGGSCRSSAMDV## out-of-frame + in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'CA' (2 nucleotides at position 161 to 162 in the user submitted sequence), (cause frameshift); gtctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaacCccctccctgcagggtcgagtcaccatgtcagtagacacgtccCAaaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagacccccaggggtttatttgtagtggtggtagctgccgctcttctgcaatggacgtctgggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtcggaact +18710 JY8QFUQ01BMD3A productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18711 JY8QFUQ01BXXFO No results +18712 JY8QFUQ01B5TGS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcaaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18713 JY8QFUQ01BMXKS No results +18714 JY8QFUQ01CXWQ9 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 184 90.91 40/44 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found cctggattcaccttcagcaagtatgccatgagctgggtccgcca +18715 JY8QFUQ01DA5P9 productive (see comment) Homsap IGHV3-7*01 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [0.17.38.11] CARVIPGRGNYAFDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 201 to 201 in the user submitted sequence), (cause frameshift); ctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacgGgctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggttcagggcttcttccccca +18716 JY8QFUQ01B97QO productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaaccggtgacggtgtcgtggaaactca +18717 JY8QFUQ01CT7RH productive Homsap IGHV4-39*02 F 983 94.12 208/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.17.38.11] CARIVVRQFDQW in-frame + tctctggtgactccatttccagtactagttattactggggctgggtccgccagcccccagggaaggggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18718 JY8QFUQ01BO4ET productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatagtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18719 JY8QFUQ01CQK7E productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVKDMIGREDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagGggaaggggttggtgtgggtcgcacgtacgaatgaagatggaaggaccacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgttgtatttgcaaatgaacagtctgagagtcgaggacacggctctttattactgtgtaaaagatatgattgggagggaggactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18720 JY8QFUQ01CJV03 unknown (see comment) Homsap IGHV4-61*03 F, or Homsap IGHV4-61*04 F (see comment) 329 61.01 133/218 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (61,01% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18721 JY8QFUQ01AB2U7 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 X 8.8.X [2.17.38.11] CARDRGLW*WCMPCR#DYW out-of-frame - stop codons gcctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcgggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18722 JY8QFUQ01BIEGC No results +18723 JY8QFUQ01B0AEI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 868 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.37.11] CAKDASRYYYNSYCDNW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 213 in the user submitted sequence), (cause frameshift) ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttattttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc +18724 JY8QFUQ01DB8ZZ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18725 JY8QFUQ01DROD3 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F (see comment) 761 81.94 186/227 nt 81.06 184/227 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 10 13 8.10.13 [2.17.38.11] CSTGGPNGYHSTYPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'TG' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); aggcctctggattcgccttcaataTGcgaagtggatgagttGgggtccgccaggctccggggaaggggcttgagtgggtcggccgcatcaagagcagcgctgatggtgcgacaacagacaccattgagcgcgtgagagacagattcaccatctcaagagatgactcaaaaaatacactgtacttgcacatgaccagcctgagaaccgaggacacaggcatgtattattgttccacaggcgggccaaatggatatcactccacatatccctggggcccggggacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18726 JY8QFUQ01CK0OK productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F (see comment) 591 73.36 168/229 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 8 10 8.8.10 [5.17.38.11] CGTFGGTHFDDW in-frame - Low V-REGION identity (73,36% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release accggaatcagattcggaagcaaattcggcaatgcctggggtcggttgggtgcgccagaagcccgggaaaggcctggagtggatgggaatcattcatccgagtgactctgaggctagatatggtccgtccttcaaaggccaggtcaccttctcggtcgacaagtccaccgatatcgcctacttgaattgggaccgcctggcggcctcggacaccgccacatattattgtggtacctttggtgggacccactttgacgactggggccagggaactgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18727 JY8QFUQ01CA2DS No results +18728 JY8QFUQ01DKH79 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactGggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgcctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18729 JY8QFUQ01AMMGW productive (see comment) Homsap IGHV3-7*01 F 973 94.06 206/219 nt 93.15 204/219 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [2.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 41 of V-REGION: 'A' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); gcctctggattcacgtttagagactattggatgagttAgggtccgccaggctccTagggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18730 JY8QFUQ01ABG07 productive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 822 86.92 186/214 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD4-17*01 F 3 8 8 12 8.8.12 [0.17.38.11] CAMTRDRGYYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggaggctccttcagcatgtatgacatcagctgggtgcgacaggcccctgggcaagggcctgagtggatgggagcgatcaaccctgtctttcgtatagcgaattacgctcagaggttccagggtagagtcaccattatcgcggacgactctacgagcacagcctacatggagctggacagcctgacgtctgaggacacggccatttattactgcgcgatgacgagggaccgcggatactactttgactcctggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccaaatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18731 JY8QFUQ01AEOFO productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame + tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +18732 JY8QFUQ01CDLSS productive Homsap IGHV3-7*01 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CATISDYRFEFW in-frame + cctctggattcacctttagtggctattggatgagttgggtccgccaggctccggggaagggtctggagtgggtggccaacatagagaaagatggaagtgacataaagtatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtctctgcaaatgaacagcctgagagccgacgacacggctatttattactgtgcgaccattagtgactaccgatttgaattctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +18733 JY8QFUQ01BE2WG productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 920 92.92 197/212 nt 91.98 195/212 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 8 8 11 8.8.11 [0.17.37.11] CAKVGNLYFFEYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 165 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 172 in the user submitted sequence), (cause frameshift) tggattcagcttcagtagctacagtatgaactgggtccgccaggctccagggaaggggctggagtggatttcatctattagcaccaccagtagtaccataggctacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgttctgcaatgaacagcctgagagacgaggacacggctgtgtactactgtgccaaagtgggtaacctgtatttctttgaatactggggccggggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18734 JY8QFUQ01CY3VH productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [0.17.38.11] CARLHGYCGGGYCYDWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 66 of V-REGION: 'C' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); tggatacagcttcaccgactattggatcggctgggtgcgccagatgcctgggaaaggcctggagtggatgggaatcatctatgttggtgacagtgataccaCgatacagcccgtccttcctaggccaggtcaccatttcagccgacaagtccaccaacaccgcctacctccagtggggcagcctgaaggcctcggacagcgccacatactactgtgcgagactccatgggtattgtggtggtggttattgctacgactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18735 JY8QFUQ01CZ93G productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 907 90.09 200/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARHSRLVRYFEFW in-frame - gtctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18736 JY8QFUQ01CNB4F No results +18737 JY8QFUQ01B2G11 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18738 JY8QFUQ01DIXIG No results +18739 JY8QFUQ01BU9SI unknown (see comment) Homsap IGHV3-7*03 F (see comment) 203 54.59 119/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (54,59% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18740 JY8QFUQ01BAYJS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18741 JY8QFUQ01A56L5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 88.94 185/208 nt 87.98 183/208 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 6 8 14 6.8.14 [X.17.38.11] CARGRATGLVDWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); caccttcaccGaactacgccatgacctgggtccgccaggctccagggaaggGggctggagtggatctcgactgttgtgggtggcggtggtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattcccagaacacgctgtatttgcaaatgtacaatttgggagccgaggacacggccctatattactgtgcgagaggtagagcgactggtctggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18742 JY8QFUQ01AJMD8 productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18743 JY8QFUQ01B5IJG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CTRELRVAAARDGVDIW in-frame - ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18744 JY8QFUQ01A89UI unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa +18745 JY8QFUQ01CRB76 productive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CATSPSDFDRRWGYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); ctctggatttagctttagaaccttttggatgagctgggtccgccaggctccagggagGggggctggagtgggtggccaacataaAagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18746 JY8QFUQ01ASKEO productive (see comment) Homsap IGHV3-48*03 F 882 89.86 195/217 nt 88.94 193/217 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [1.17.37.11] CARESWWSGFYGWYNPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 123 in the user submitted sequence), (cause frameshift) cctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcataGcattagtgatagtggtagtcgcatttactatgcagactctgtgagggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacaacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18747 JY8QFUQ01AFD6W productive (see comment) Homsap IGHV3-11*01 F 811 85.84 188/219 nt 84.93 186/219 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [2.16.38.11] CADIKLGDWCFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 43 in the user submitted sequence), (cause frameshift) cgcctctggattcacctttagcagctatgccatgagctggatcgccaggctccaggaaaggggctggaatggaAttttatatattagcaccagtggtaatatgatctattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaggtcgatgtatttgcagatgaacagtctgagagccgaggacacggccgtctatttctgtgccgatataaaactgggtgactggtgcttcgatctctggggccgtggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18748 JY8QFUQ01BUG8O productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 942 92.27 203/220 nt 91.36 201/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); ggcctctggattcacctttggGttattatggcatggactgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18749 JY8QFUQ01ABGL7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcgaaggactacttccccgaaccggtgacggtgtcgtggaactc +18750 JY8QFUQ01BO1DB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacctttagcCacttttgccgtgacctgggtccgccaggctccagggaagggtctggagtgggtctcaactattagcggtagtgatggtagcaaatactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacactgtatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18751 JY8QFUQ01BKTU0 No results +18752 JY8QFUQ01BNONJ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-10*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARKRVPGGDFLWGTTG in-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccgggggggactttttatgggggactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgga +18753 JY8QFUQ01CIS2I No results +18754 JY8QFUQ01CDY8Q productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt 84.86 185/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-20*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGLTTMTGNGLEHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 169 to 169 in the user submitted sequence), (cause frameshift); tctctggattcacccttcgcagatatggcatggcgtgggtccgccaggctccggGggaaggggctggagtgggtctcatcttctaacagtagtgatgaatccacatactatgcagactccgtgaagggccgcttcaccatttccagagaccattccaagaacacggtgCtttttgcaaatgtacagcctgagagccgaagacacggccctctattactgtgcgagagggctaacaacaatgacagggaatggtcttgagcactggggccagggagccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18755 JY8QFUQ01AOGPF productive (see comment) Homsap IGHV3-33*03 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctcccagccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18756 JY8QFUQ01CWMJ0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtgcgtggaactca +18757 JY8QFUQ01BVSN2 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); cctctggattTcatcttcagtagctatgccatgagttgggtccgccaggctccagggaaggggctggaatGgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18758 JY8QFUQ01C11XL productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 899 91.16 196/215 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [0.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame - ctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18759 JY8QFUQ01BMJ5W No results +18760 JY8QFUQ01AHPHF unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttaatagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccgaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18761 JY8QFUQ01C6KZA unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 932 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD3-10*02 F 2 8 8 X 8.8.X [1.17.38.11] CAREFPGAFFGQ#YGMDVW out-of-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattcctcttcagtagctttaacatgaactgggtccgccaggttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttccgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18762 JY8QFUQ01C7QY8 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 930 91.03 203/223 nt 90.58 202/223 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [1.17.38.11] CTTAPSETYATEYFAMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgccCcccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc +18763 JY8QFUQ01AX3XE unproductive (see comment) Homsap IGHV1-2*02 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [0.17.38.11] CARGGDDVGTIIGE##DSW out-of-frame + stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 69 of V-REGION: 'AA' (2 nucleotides at position 112 to 113 in the user submitted sequence), (cause frameshift); tggatacacgttcaccgactactatgtccactgggtgcgacaggcccctggacaagggcttgagtggatggcgtggatcaaccctaacattggtgtcaccaagtctgcacaAAaaattttcagggcagggtcaccatgaccagggacacgtccatcagcacagccttcatggagctgagcagcctgagatctgacgacacggccgtttattactgtgcgagagggggggacgacgtgggaactattattggggaatcttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18764 JY8QFUQ01CPSVL No results +18765 JY8QFUQ01CZYOR unknown (see comment) Homsap IGHV3-33*03 F 937 92.24 202/219 nt 8 8 X 8.8.X [2.17.38.X] null + No rearrangement found gcgtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggcagcagtggctggtttggacgttgtggacgtctgggggccaagggtaccgacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18766 JY8QFUQ01DLNUP productive Homsap IGHV2-26*01 F, or Homsap IGHV2-5*01 F or Homsap IGHV2-5*02 F or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*08 F or Homsap IGHV2-5*09 F or Homsap IGHV2-70*12 F 155 100.0 32/32 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-1*01 F 3 X X 9 X.X.9 [X.X.10.11] CAHGTAPFDYW in-frame - tggaccctgtggacacagccacatattactgtgcacacgggacggccccttttgactactggggccagggaaccctggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18767 JY8QFUQ01DWXOZ No results +18768 JY8QFUQ01B7D3E No results +18769 JY8QFUQ01C85E7 unproductive Homsap IGHV3-30*08 F, or Homsap IGHV3-30*16 F 923 91.74 200/218 nt 89.91 196/218 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGKAGHTHYGLDV## out-of-frame + in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); cctctgcattcaccttcagtagttatgctatgcactGgggtccgccaggccCccaggcaaGggggctagagtGgggtggcagttatatcaaatgatggaaattataacgactatgcagactccgtgaaggggcgattcaccatttccagagacaactccaagaacacgctatttctacaaatgaatagcctgagagttgaggacacggctgtctataactgtgcgagaggaaaggctggccatacccactacggattggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18770 JY8QFUQ01AOAA4 productive (see comment) Homsap IGHV3-7*01 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [0.17.38.11] CVRGRDGVNFGEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctgggttcatctttagtagacattggatggcctgggtccgccaggctccagGggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18771 JY8QFUQ01CCE8Y productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 947 92.31 204/221 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAREVIPTATYGMDLW in-frame - Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cagcgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18772 JY8QFUQ01BCF23 productive Homsap IGHV3-30*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactggatccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18773 JY8QFUQ01BDIDH unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 311 60.09 131/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (60,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctaaattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcacaggtattagcagtggtggtatggacgtctggggccaagggaccacggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18774 JY8QFUQ01ACPP2 productive (see comment) Homsap IGHV3-66*02 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.17.38.11] CAKLADTGEWSNRIFYFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaCccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18775 JY8QFUQ01AQXAS productive Homsap IGHV4-61*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERSISIGGAREFDSW in-frame - Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tcactggtggccccatgggcagtagtttatacttctggaattgggtccgacagcccgccgggaagagactggagtggatcggacgtgtttatgatgatgggagtacccgctacaatccctccctcaggggtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaggttgagttttgtgaccgccgcagacacggcccgttattactgtgcgagagaacggagtatttcgattggcggagcgagagaatttgactcttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18776 JY8QFUQ01AN75J unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CANEVGYCSGG# out-of-frame + ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +18777 JY8QFUQ01A2YVQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 693 80.18 174/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD5-12*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKSPDSGYDSNWLDPW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaacttggcgaagttcgccatgagctgggtccgccaggctcctgggaaggggctggagtgggtctcagagatcagtggctccggtagtaaagtcggatatgcggagtccgtgaagggccgattcaccatctccaaagacaattccaagaacacattgtacttgcaaatgaccgacctgagacccggcgacacggccatttattactgtgcgaaaagtcctgatagtggctacgattctaactggctcgacccctggggcctgggaaccctggtcaccgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +18778 JY8QFUQ01DVLSR unproductive Homsap IGHV3-30*08 F, or Homsap IGHV3-30*16 F 933 91.82 202/220 nt 90.91 200/220 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [2.17.38.11] CARGKAGHTHYGLDV## out-of-frame - in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 130 to 130 in the user submitted sequence), (cause frameshift); agcctctgcattcaccttcagtagttatgctatgcactgggtccgccaGggccccaggcaaggggctagagtgggtggcagttatatcaaatgatggaaattataacgactatgcagactccgtgaaggGggcgattcaccatttccagagacaactccaagaacacgctatttctacaaatgaatagcctgagagttgaggacacggctgtctataactgtgcgagaggaaaggctggccatacccactacggattggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18779 JY8QFUQ01DPDLC productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + cgtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcactctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18780 JY8QFUQ01CD8Q5 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 111 95.83 23/24 nt 6 X X 6.X.X [1.X.X.X] null + No rearrangement found cctctggattcacctttagtagat +18781 JY8QFUQ01BWCNH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1058 98.62 215/218 nt 98.17 214/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*03 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'CA' (2 nucleotides at position 77 to 78 in the user submitted sequence), (cause frameshift); cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcCAgcgtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18782 JY8QFUQ01CI9ZU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVKEDHDSGLRVLLEW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 50 of V-REGION: 'TG' (2 nucleotides at position 64 to 65 in the user submitted sequence), (cause frameshift); ctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggagggggcgTGgaggtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18783 JY8QFUQ01CFQU8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18784 JY8QFUQ01BRDHQ productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'A' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtacctatAggcatgctctgggtccgccatgttgcaggcaaggGggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18785 JY8QFUQ01CXOCE productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcttccccgaaccggtgacggtgtccgtggaactnag +18786 JY8QFUQ01CRW90 No results +18787 JY8QFUQ01DCBBE productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 896 90.37 197/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggatcacctttggttattgatggcatgagctgggtccgccaagctccGggggagggggctggagtgggtctctggtattGaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaaggggcccatccggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +18788 JY8QFUQ01C5NUH No results +18789 JY8QFUQ01AYZ9S productive (see comment) Homsap IGHV3-48*01 F (see comment) 749 83.96 178/212 nt 82.08 174/212 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [0.17.38.11] CSRDGRRGYDLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 200 to 200 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 81 in the user submitted sequence), (do not cause frameshift) ctggattcaccttcggaacctatgGccatgacgtgggtccgcctgactcctgggaaagggctggagtGgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacgGgctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +18790 JY8QFUQ01COTG1 No results +18791 JY8QFUQ01CGZZ6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.37 197/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AAGT' (4 nucleotides at position 78 to 81 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'T' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAAGTgtcagtagtagtactggtTattttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18792 JY8QFUQ01CY15D unproductive Homsap IGHV3-7*01 F 931 92.59 200/216 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CATDDSNGWDEVADY## out-of-frame - tctggattcaccttcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18793 JY8QFUQ01AB1K5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +18794 JY8QFUQ01AFPCT unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 743 82.57 180/218 nt 81.65 178/218 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [1.17.38.11] CARIWDSWSGA#FDVW out-of-frame - stop codons Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'C' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cctctggattCcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggGggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagctttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +18795 JY8QFUQ01BN0BZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +18796 JY8QFUQ01CYNUI productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 18 8.8.18 [2.17.38.11] CVRESGDYGGKYSKSYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); gcctctggattcactttcagtagttatagcatgaactGgggtccgccaggctccagggaaggggctggagtgggtctcatcaattactagaagttctagttatatgtcctacgcagactcagtgaagggccgattcaccatctccagagacaatgccgagaattcactgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgtgagagaatcgggtgactacggtggtaaatatagcaagtcatactttgactattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18797 JY8QFUQ01C93RZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggGggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18798 JY8QFUQ01A5JVK productive Homsap IGHV3-48*01 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + cctctggattcgccttcagtagttccagcatgaactgggtccgccagggtccagggaaggggctggagtggatttcacacattaggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +18799 JY8QFUQ01AAZV6 No results +18800 JY8QFUQ01DCE2O productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARPLRATYGDYVNW in-frame + cctctggattcaccttcgataactatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcaaaggatggaagtattgaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacaatttatctgcaaatgaacattgtgagggttgaggacacggctatgtattactgtgcgagaccccttcgggcaacttacggtgactacgtgaactggggccagggaaccctggtcaccgtctcctcagcatccccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggctccggggcttcttccccca +18801 JY8QFUQ01A4H4P productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 796 99.38 161/162 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 2 X 7 12 X.7.12 [X.9.38.11] CARSRTFYGSANYW in-frame - gggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacgactgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggttttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18802 JY8QFUQ01CI12B productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1008 98.56 205/208 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-17*01 F 2 6 8 16 6.8.16 [X.17.38.11] CARQLDYGDYSRHGLDVW in-frame + caactttaccggctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccgtgtattactgtgcgagacaattagactacggtgactactctaggcacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcatcgcctgcctggtccagggcttcttccc +18803 JY8QFUQ01CC2MU unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 970 93.24 207/222 nt 92.79 206/222 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [3.17.38.11] CARGAQLLCQ*WA*LL# out-of-frame - stop codons in FR2-IMGT at codon 50 of V-REGION: 'GC' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift); gcagcctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggGCttggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagaggggcacagttattatgtcagtagtgggcctgactactgggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18804 JY8QFUQ01AJBHH productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18805 JY8QFUQ01CTB12 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18806 JY8QFUQ01AL7F1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactc +18807 JY8QFUQ01CAHX8 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 747 82.95 180/217 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CGRDERGADLPNDS## out-of-frame + stop codons Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagcttttccatggggtgggtccgccaggctccagggcggggactggagtaggtctcagccattgacggtcttactggtggtacatattacgcggactccgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagccccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctggggccctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18808 JY8QFUQ01BT10B productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18809 JY8QFUQ01CU3GP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - cctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaatgtggtcgtcgcatgcctggtccagggcttcttccccca +18810 JY8QFUQ01C9MNR productive (see comment) Homsap IGHV4-39*02 F 1005 95.45 210/220 nt 94.55 208/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.16.38.11] CARIVVRQFDQW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift) tctctagtggActccatcagcagtactaattactactggggctgggtccgccagcccccagggaagggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +18811 JY8QFUQ01BUIMD productive Homsap IGHV3-7*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRDRFYDSSGYEFGELGDYSDHW in-frame + ctctggattcacatttagtaactactggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctgtgtgagagatcgattttatgatagtagtggttatgagtttggggaattgggggactactctgaccactggggccagggaacccaggtgcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18812 JY8QFUQ01C7GNQ unproductive Homsap IGHV3-48*02 F 882 89.4 194/217 nt 88.48 192/217 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CASGGVTEAHY## out-of-frame + in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'T' (1 nucleotides at position 210 to 210 in the user submitted sequence), (cause frameshift); ctctggattcagctccagtgaatataccatgaactgggtccgccaggctccagggaaggggctggagtgggTtttcatacattggtgttggtactggtggcatatactacgcagactctgtgaggggccgattcaccatctccagggacaatgccgagaactcagtgcatctgcaaatgaacagcctgagagacgacgacacgggtgttTtattactgcgcgagcggaggggtgacagaggctcactactggggccagggaacccctggtcaccgtctcgtcagcatcccccggaccagcccccaaagggttcttccccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca +18813 JY8QFUQ01C9D98 productive (see comment) Homsap IGHV3-11*01 F 984 95.79 205/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD1-1*01 F 3 8 8 13 8.8.13 [1.17.37.11] CARVNTWNADYFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 3 nucleotides (from position 104 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcagtgactactacatgatctggatccgccaggctccagggaaggggctggagtgggtttcatacattactagtcgtggtactatcatgtacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggccatttattactgtgcgagagtgaacacatggaacgccgactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18814 JY8QFUQ01CMLGK productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 7 8 16 7.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaattctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccaaagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccgagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttccccca +18815 JY8QFUQ01BGBBU productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18816 JY8QFUQ01AJF1C No results +18817 JY8QFUQ01CPWIM productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgggcaactcag +18818 JY8QFUQ01CVSEP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-21*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtttattactgtgcgagaggccgaatagtgtcggttggtatgtcaggctggttcgacccctggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18819 JY8QFUQ01BU28D No results +18820 JY8QFUQ01A7GGK No results +18821 JY8QFUQ01BWFRJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18822 JY8QFUQ01CDQM0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 682 92.45 147/159 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-16*01 F 2 X 8 13 X.8.13 [X.7.38.11] CTRGGNYDPIPPNNW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gggctggattgggtctcacgtatcaatactgatgggagcatcagaagcttcgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgggagccgaggacacggctgtgtattattgtacaagaggggggaactatgaccccatcccgccgaacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18823 JY8QFUQ01B1E9Y productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.37.11] CVREGRGTAAYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 177 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaataacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18824 JY8QFUQ01DMNPS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18825 JY8QFUQ01C2BRO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 7 16 8.7.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ccctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcaatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca +18826 JY8QFUQ01ANV52 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18827 JY8QFUQ01B978H productive (see comment) Homsap IGHV3-74*03 F (see comment) 793 84.93 186/219 nt 84.02 184/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 30 of V-REGION: 'TC' (2 nucleotides at position 18 to 19 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); gcctctggattcacgttTCcacacctcctggatggcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaAagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18828 JY8QFUQ01B65L5 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame + cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc +18829 JY8QFUQ01B672S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccagtgacggtgtcgtggaaactc +18830 JY8QFUQ01AMFZF productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1080 97.79 221/226 nt 96.9 219/226 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'T' (1 nucleotides at position 136 to 136 in the user submitted sequence), (cause frameshift); ctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtcCcccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaaTgtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatcccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccg +18831 JY8QFUQ01ABB70 productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18832 JY8QFUQ01DC4CD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 834 86.82 191/220 nt 86.36 190/220 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CVKEDHDSGLRVLLEW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); aggctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggaGgggggctggagtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18833 JY8QFUQ01AC33X productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 776 83.71 185/221 nt 83.26 184/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFETW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tttccggtagttccatcagtagcagtgattactactGggggctgggtccgccagtccccagggaagggtctggagtggattggaagtgtctattacagggggacgcagtacctcaacccgtccctccagagtcgagtttccatttccattggcacgtccaagacgcaattctccctgagactgaggtctgtgaccgccgcagacacggctatgtattactgtgcgagacatcggtcttttggagtgataattgtgaattactttgagacctggggacagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18834 JY8QFUQ01B5F34 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 869 88.99 194/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARVFSGVAAPPDSW in-frame - cctctggatttcccttcaccagttactggatgcagtgggtccgccaagctccagggaaggggctggtctgggtctcacttagtaatagtgatgggagcactactacctacgcggacgccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatcttcaaatgaatcatctgagagtcgaggacaccgctgtatatttctgtgcgagagttttcagtggtgtcgctgctcccccggactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18835 JY8QFUQ01ARJHI productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 21 8.8.21 [1.17.38.11] CVRVGAPYYDFWSGYQTNWFDPW in-frame - gtctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgcaagtactacttccatacattatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggcgccatattacgatttctggagtggctatcagactaactggttcgacccctggggccagggaactctggtcaccgttacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +18836 JY8QFUQ01ATFTP productive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD4-23*01 ORF 2 10 7 17 10.7.17 [1.17.38.11] CARGECGVNCPYYNWYQHW in-frame + tgtctggtggctccatcagcagtgatgattactactggagctggatacggcagtccgccgggaagggactggagtggattgggcgaatttataaaagtggcgacacagtgtacaacccctccctcggggggcgagtcgccatgtcactggacacgtccaagaaccaattctccctgaggttgacttctgtgaccgccgaagacacggccgtctattactgtgcgaggggtgagtgcggtgtcaactgcccctactacaactggtaccaacactggggcccgggaacccgggtcaccgtcacgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccccca +18837 JY8QFUQ01AHY6K productive Homsap IGHV1-3*01 F 817 87.32 186/213 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [X.17.38.11] CVRGRSPPGDWFDPW in-frame - ggatacaccttcactaattatgctctgcaatgggtgcgccgggcccccggacaaacttttgagtggctgggatggatcaactctgccaatggcaacacaaaatattctcagaagtttcagggcagagtcgccattaccagggacacatccgcgaggacaacttacatggaattgagcagtctgacatctgaagacacggcgacatattattgtgtgagaggaagaagtccgcccggcgactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18838 JY8QFUQ01DJ75W productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18839 JY8QFUQ01CDJVP productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18840 JY8QFUQ01AOYJ9 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18841 JY8QFUQ01C3DVY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 971 94.88 204/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 2 8 8 12 8.8.12 [0.17.38.11] CAKDQAVAGGFDYW in-frame - ctggatttacctttagctcctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtcgcaattattagtggtagtgatggtcgcacatactacgccgactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaataaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcaagcagtggctggaggatttgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18842 JY8QFUQ01AKBRD productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt 94.86 203/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.16.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift) ctggattcaccttcagtagctactggatcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18843 JY8QFUQ01AMFPR productive Homsap IGHV3-7*01 F 911 90.5 200/221 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [2.17.38.11] CARVIPGRGNYAFDVW in-frame - cagcctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18844 JY8QFUQ01DJI0O productive (see comment) Homsap IGHV3-30*10 F (see comment) 715 81.48 176/216 nt 80.56 174/216 nt Homsap IGHJ1*01 F 152 76.92 40/52 nt Homsap IGHD1-1*01 F 1 7 8 16 7.8.16 [1.17.37.11] CSRGTTGTTDDSRLFQHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 157 in the user submitted sequence), (cause frameshift) cctctggattcagcttcggcattacgccatgcactgggtccgccaggctccaggcaagggcctagagtgggtggctgtcataaataaggctgggaagactaaacattatatagactccgtgaagggccgattcaacgtctccagagacaactccgaaaaacactctatttggagatgaataacgtgggagttgaggacacggctgtatattattgttcgagaggtaccacggggacgacagacgactcgaggttgttccaacactggggccagggcgccctggtcaccgtttcgtcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18845 JY8QFUQ01CRKLQ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*05 F or Homsap IGHV3-30*13 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 131 83.78 31/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcagcctcacttcctatggcatgaactgg +18846 JY8QFUQ01AB3H4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 564 73.18 161/220 nt 71.82 158/220 nt Homsap IGHJ4*02 F, or Homsap IGHJ5*01 F or Homsap IGHJ5*02 F 99 68.89 31/45 nt Homsap IGHD6-6*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKASF## out-of-frame - Low V-REGION identity (73,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); gtgtctgggggtcaccttcggtgactatgccaGtgggctggatccgccagtctcctgggggggggcCtgcagtgggtcgctgctataagtcctgacggaaaaaaCgactttctacgcagactccgtggcgggccggttccacatttatagagacaatccaataaaaactgtttttctgcaaatgaatggcctgagagtcgaagacacggccatctattactgtgcgaaggcgtccttttggggggcagggatcccaggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18847 JY8QFUQ01A0JPR unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 892 89.95 197/219 nt Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD6-25*01 F 1 8 8 X 8.8.X [2.17.38.11] CTRVFSGVAAP#DLW out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctctggattcgcctttagaagttactggatgcactgggtccgccaagttccaggaaaggggctggtgtgggccgcactcactaatagtgatgggagtgtcacaacctacgcggattcagtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatttgcaaatgaatagtctgagagccgacgacacggccgtttattattgtacgagagttttcagtggtgtggcagcgccccggacctttggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18848 JY8QFUQ01DU2T0 No results +18849 JY8QFUQ01AZA1D productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F (see comment) 773 83.04 186/224 nt 82.59 185/224 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 10 13 8.10.13 [1.17.38.11] CSTGGPNGYHSTYPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattcgccttcaatatcaagtggatgagttgggtccgccaggctccggGggaaggggcttgagtgggtcggccgcatcaagagcagcgctgatggtgcgacaacagacaccattgagcgcgtgagagacagattcaccatctcaagagatgactcaaaaaatacactgtacttgcacatgaccagcctgagaaccgaggacacaggcatgtattattgttccacaggcgggccaaatggatatcactccacatatccctggggcccggggacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18850 JY8QFUQ01B781B productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 948 93.93 201/214 nt 92.99 199/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD2-8*02 F 3 8 7 14 8.7.14 [1.16.38.11] CARGRCGLVGCWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 170 to 170 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) tctatggtgggtccttcagtggttactactggagctggatccgccagtcccagggaaggggctggagtggatcggggaaatcaatcataatggatccaccagctacaacccgtccctcaagggtcgagtcaccatatcagtagacacgtccaagaaccagttctccctaAaagctgagttctgtgaccgtcgcggacacggctgaatatttctgtgcgagaggtcgctgcgggcttgtggggtgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18851 JY8QFUQ01AY5UE No results +18852 JY8QFUQ01C73V4 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 927 92.17 200/217 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-16*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARHNYGNEKYIMDVW in-frame + ttttggatacaactttgccacctattggatcggctgggtgcgccacatgcccgggaaaggcctggaatggatggggatgatctttgctggtgactctgacaccagatacagtccgtccttccgaggccaggtcaccatgtcagccgacaagtccatcaacaccgcctacctgcagtggagcagcctgatggcctcggacaccgccatatattactgtgcgagacataattatggaaacgagaagtacattatggacgtctggggccaggggaccacggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18853 JY8QFUQ01ARHTV unproductive (see comment) Homsap IGHV3-48*04 F, or Homsap IGHV3-69-1*01 P (see comment) 353 74.81 98/131 nt 74.05 97/131 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD2-15*01 F 1 X 5 12 X.5.12 [X.X.38.11] CAKGGW*RRP*LLG in-frame - stop codons Low V-REGION identity (74,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); ctctggattcaccctttagtaaccattggatgaactggggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtatTtactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18854 JY8QFUQ01CU8N8 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); cctccggattcaccGtttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18855 JY8QFUQ01BRZLC productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 701 80.93 174/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [1.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame + Low V-REGION identity (80,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18856 JY8QFUQ01BFD4A productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18857 JY8QFUQ01CM4DL productive (see comment) Homsap IGHV3-30*01 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAGDLTGVPYYYDSSGLKYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctagattcaccttcagtagctataatatgcactgggtccgccaggctccaggcaaggGggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +18858 JY8QFUQ01CEO3U No results +18859 JY8QFUQ01AF3TS productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTRSSNSAYDYW in-frame - ctctggattcacgtttagtaacagttggatgggctgggcccgccaggctccagggaaggggctggagtgggtggccagcacaaaccaagatgcaagtgagaaaaagtatgtggactctgtgaggggccgattcaccatctcaagagacaacgccaagaactcactgtatttacaaatgaacagcctaagagccgaggacacggctttatatttctgtacgaggtccagtaacagcgcttatgactattggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18860 JY8QFUQ01BBTA4 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD4-17*01 F 3 10 7 X 10.7.X [1.17.38.11] CARRWARQRLVMDYFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); tctctggtggActccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtgtacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactgggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctcccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18861 JY8QFUQ01CKTAT unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGVRGVGAYYIYYFDL## out-of-frame + ctctggattcacctttagtacctattggatgggctgggtccgccagactccagggaaggggctggagtggctcgcaactattagtggtagtggaagtagatcattttacgcagactccctgaagggccggttcaccatctccagagacaattccaagggcacggtatacctggaaatgaccaccctgagagccgaggacacggccgtatattactgtgcgagagatggggtccgtggcgttggtgcttactacatctactattttgacttatgggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt +18862 JY8QFUQ01CH5GA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18863 JY8QFUQ01BBGSE productive Homsap IGHV3-48*01 F 860 88.53 193/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + tctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18864 JY8QFUQ01B27FW No results +18865 JY8QFUQ01BL28Q productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame - gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18866 JY8QFUQ01AD2PJ No results +18867 JY8QFUQ01B9FNC No results +18868 JY8QFUQ01BFJVH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.37.11] CVSDLAGQKGFW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18869 JY8QFUQ01BG8NO productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + ctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18870 JY8QFUQ01CB08I productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18871 JY8QFUQ01CUUK1 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 3 9 7 14 9.7.14 [1.17.38.11] CARLLAPSAVGPFDFW in-frame + tctctggtgactccatcagcggtagcaattggtggagttggatccgccagcccccagggaaggggctggagtggattggggaaatctctcatagtgggaacactaactacaacccgtccctcaagagtcgggtcaccatatcagtcgacaagtccaagagccagttctccctgaacctgagcgctgtcaccgccgcggacacggccgtatattactgtgcgagactgctcgccccatcggccgtgggaccctttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca +18872 JY8QFUQ01A46LV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGVDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 83 of V-REGION: 'T' (1 nucleotides at position 153 to 153 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatTttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtgtggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcttccccgaaccggtcgacggtgtcgtggcaactcag +18873 JY8QFUQ01B6P8J productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18874 JY8QFUQ01B7921 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVRGRIVSVGMAGWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); tctctggattcaccttcaGggaactattggatgcactgggtccgccaagctccagggaaggggctggagtgggtctcacgtatcaatggcgacggaagtagcacaagctacgcggactccgtgaagggccgattcaccatctccagagacaacgccgagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacagccgtatatttttgtgtaagaggccgtatagtgtcagttggtatggcaggctggttcgacccctggggccagggaacgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18875 JY8QFUQ01AJQB3 unproductive (see comment) Homsap IGHV3-11*01 F 904 91.2 197/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGPPYLYGSHGNSFDQ## out-of-frame - stop codons tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtgggtaacccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccacgggaaccctagtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcatagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18876 JY8QFUQ01DM42W No results +18877 JY8QFUQ01B77QK productive Homsap IGHV4-4*07 F 858 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18878 JY8QFUQ01AAXK2 unproductive Homsap IGHV3-9*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CVKDRKGSNWYYFG#W out-of-frame - ctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttggaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18879 JY8QFUQ01BPYN9 No results +18880 JY8QFUQ01ANHVK productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18881 JY8QFUQ01A6BZG unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 689 79.82 174/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (79,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18882 JY8QFUQ01B0ZXZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - ctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +18883 JY8QFUQ01BF5MU No results +18884 JY8QFUQ01A836E productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 929 91.4 202/221 nt 90.5 200/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [3.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 63 in the user submitted sequence), (cause frameshift) gcagcctccgaattcaTccttgagcagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18885 JY8QFUQ01BXUGL productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtagaact +18886 JY8QFUQ01CO10V unproductive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 840 88.32 189/214 nt 87.85 188/214 nt Homsap IGHJ5*02 F 146 77.55 38/49 nt Homsap IGHD3-9*01 F 3 8 7 X 8.7.X [1.17.38.11] CGRGTG#DLW out-of-frame + stop codons in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcacggttgaggattatggcgtgagctgggttcgccaagttccagggaaggggctggagtgggtctctggtcttaatttgaatggtgccacaggttatgcaaagtccgtgacgggccggtttaccatctccagagacaacgccaagaactccctgtatttggaaatggatagtctgagagtcgaagacacggccttctattattgtgggagagggacggggtgacctctggggccggggaatcctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18887 JY8QFUQ01B89TY No results +18888 JY8QFUQ01BADXF unproductive Homsap IGHV4-4*07 F 854 88.84 191/215 nt Homsap IGHJ3*02 F (see comment) 160 80.0 40/50 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [1.17.38.11] CAGRNGNL##FYMW out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) tatctggtggttcgatcgtcagttactactggagttggatccggcagtccgccgggaagggactggagtggattgggcgcatctactccaatggggatacgaactacaatccctccctcaagggtcgagtcaccatgtcagtagacccttccaacaaccagttctccctgaggttgagctctgtgaccgccgcggacacggccgtatattactgtgcgggaagaaatggaaatttggcctttttatatgtggggccaagggacgactgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18889 JY8QFUQ01CWQID productive Homsap IGHV1-2*02 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDWGGTYAPLDNW in-frame - tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaaccttgaccagtgacacgtccatcagtacagcctacatggaaatgagcgggctgacgtctgaggacacggccatcttttactgtgcgagagattggggtggcacgtacgctccgcttgacaattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18890 JY8QFUQ01CHG9Q No results +18891 JY8QFUQ01BJURD productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 15 10.7.15 [1.17.38.11] CARNPSYSNSHQHCDYW in-frame + tctctggtgcctccatcaacagtggtagttactactggagttgggttcggcagcccgccgggaagggactggagtggattgggcgtatctacaccagtgggagcaccaactacaacccctccctcaagagtcgagtcgccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctatttttgtgcgagaaatccctcttatagcaattcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18892 JY8QFUQ01CHYC3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 985 95.37 206/216 nt 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgGttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctttatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18893 JY8QFUQ01CA5NT productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 7 8 11 7.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) tctctggattcacctttagtaggtttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18894 JY8QFUQ01BOIKV No results +18895 JY8QFUQ01CMFZX productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 940 93.06 201/216 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [2.17.38.11] CARAPRTATLLDPW in-frame - gtctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18896 JY8QFUQ01BAV1L unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +18897 JY8QFUQ01A8YFM No results +18898 JY8QFUQ01BV3BU No results +18899 JY8QFUQ01BB36Q productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18900 JY8QFUQ01BQW5X unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + tctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18901 JY8QFUQ01CEG44 No results +18902 JY8QFUQ01CA7NB productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 728 82.33 177/215 nt 81.4 175/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 3 8 6 15 8.6.15 [2.17.38.11] CARDWGGSFDRYYFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) gtccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggctgggAgacatcaactttaaaggaagcacaattacaacccgtccctcaagagtcgactcaccatattagcagacttgtccaggaatcgcttctctctagaactaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtgggagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18903 JY8QFUQ01B6AAU productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 819 86.64 188/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-17*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARHSGALATGSQNWFDPW in-frame + gtcgggatttaggtttgatgattttggcatgagctgggtccgccaagttccagggaagggcctggaatgggtctctggtagtgactggagtggtggaagaacaggttatggtgactctgtgaagggacgattcatcatctccagagacaacgccaagaactccctatatctacaaatgaacgatctgcgagccgatgacacggccgtctattattgtgcgcgacatagtggggcgctggctactgggtctcagaactggttcgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18904 JY8QFUQ01DPKTF unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 971 94.42 203/215 nt 93.49 201/215 nt Homsap IGHJ6*04 F (see comment) 99 61.9 39/63 nt Homsap IGHD6-6*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARAPRGEYSNSSV*LLG in-frame - stop codons Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'TGG' (3 nucleotides at position 76 to 78 in the user submitted sequence), (do not cause frameshift); tctatggtgggtccttcactgactcctattggagctggatccgccagcccccagggaaggGggctggagtgcattTGGgggaaaatcaatcatagtggaagaaccaactacaacccgtctctcaagagtcgagtcaccatatcagtagacccgtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggctgtgtattactgcgcgagagccccaaggggggagtacagcaactcgtccgtttgactactgggggccaggggaaccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +18905 JY8QFUQ01B9IMG productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt 91.59 196/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 97 of V-REGION: 'CG' (2 nucleotides at position 194 to 195 in the user submitted sequence), (cause frameshift); tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaAaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccCGggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18906 JY8QFUQ01CF3LD unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CAREKGSGPPH#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18907 JY8QFUQ01BC3PM productive Homsap IGHV4-61*02 F 974 93.67 207/221 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD2-2*01 F 2 10 7 19 10.7.19 [1.17.38.11] CARVVRCTTTGCSRVGWFDPW in-frame + tctctggtggctccatcagcagtgatgattactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctcttccagtgggaacaccaactacaacccctccctcaggagtcgagtcaacatttcactagacacgtccaagacccagttctccctggagctgacctctgtgagcgccgcagacacggccgtgtattactgtgcgagggtcgttcgttgtactacgaccggctgctcaagggtaggatggttcgacccctggggccagggaaccctggtaaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +18908 JY8QFUQ01CEXJ3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ4*01 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDGVRGVGAYYIYYFDLW in-frame + ctctggattcacctttggcctctatgccatgaactgggtccgccagactccagggaaggggctggagtggctcgcaactattagtggtagtggaagtagatcattttacgcagactccctgaagggccggttcaccatctccagagacaattccaagggcacggtatacctggaaatgaccaccctgagagccgaggacacggccgtatattactgtgcgagagatggggtccgtggcgttggtgcttactacatctactattttgacttatggggccaaggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18909 JY8QFUQ01B81TC productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 976 92.89 209/225 nt 92.44 208/225 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-16*02 F 1 10 9 16 10.9.16 [1.17.37.11] CAKDPQQLLEDINWFDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 89 of V-REGION: 1 nucleotides (from position 179 in the user submitted sequence), (cause frameshift) ctccggggacagtgtctctagcaacagtgccacttggaactggatcaggcagtccccaacgggaggccttgagtggctgggaaggacatcctacaggtccaaatggtatagtgattatgcggtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctcctgcaattgaactccgttagtcccgaggacacggccgtctattactgtgcgaaagatcctcagcagttattggaagacataaactggttcgacccctggggccagggcacccaggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18910 JY8QFUQ01B3FJT productive Homsap IGHV1-2*02 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame + tggatatactttcaccgaccattatgtttactggatgcgacaggcccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18911 JY8QFUQ01A6E8N productive Homsap IGHV1-2*04 F 885 90.65 194/214 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [0.17.38.11] CARERIFGADYYYYHGMDVW in-frame + tggatacagcttcaccgactactatatacactgggtgcgacaggcccctggacaggggcctgagtggatggggtgtatcaaccctaatactggtgacacaagatattcacggaagtttcaggcctgggtcaccatgaccagggacacgtccatccgcacggcctacatggagctgagcagcctgaaatctgacgacacggccgtgtattcctgtgcgagggagcggatttttggagccgattactactactaccacggaatggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +18912 JY8QFUQ01DQC2Y productive Homsap IGHV3-30*07 F 842 87.61 191/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [1.17.38.11] CASLGSYESSGPRW in-frame + cctctggattcctcttcagtagttatgctatacactgggtccgccaggctccaggcaaggggcttgagtgggtggcggttgtttcatatgatggaaataataaattttacgcagactctgtgaagggtcgattcagcctctccagagacaactccaagagcacggttgatctgcaaatggacaacttgagatccgaagacacggctgtatattattgtgcgagcctcggttcctatgagagcagtggtccccgatggggcccgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18913 JY8QFUQ01CV3LG unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18914 JY8QFUQ01C9Y1A No results +18915 JY8QFUQ01AJQ34 unproductive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD1-1*01 F 1 8 7 X 8.7.X [1.17.38.11] CARGSSKAYNWFD#PG out-of-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18916 JY8QFUQ01CX1MR productive Homsap IGHV3-7*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + cctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaacctcag +18917 JY8QFUQ01BKIC6 productive (see comment) Homsap IGHV3-30*01 F 937 92.24 202/219 nt 91.78 201/219 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [2.17.38.11] CVKNDLSWGTIEHYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); gcctctggattcacgttcaacatttatgGgtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18918 JY8QFUQ01C4EP3 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +18919 JY8QFUQ01B2HTR productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18920 JY8QFUQ01BZ690 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18921 JY8QFUQ01B7WTW productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18922 JY8QFUQ01BDNIC productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 878 88.99 194/218 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD2-2*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARYCSSDSCQGYHDAFDVW in-frame - cttctggatacatcttcacgaaccactggatcggctgggtgcgccagatgccgggtagaggcctggagtggatggggatcatctatcctggtgactccgattccagatacggcccgtccgcccaaggccaggtcaccttctcagtcgacaagtccatcgccaccgcctaccttcagtggagtagcctgaaggcctcggataccgccacgtactactgcgcgagatattgtagtagtgacagctgccaagggtaccatgatgcttttgatgtctggggccaagggacaatggtctccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18923 JY8QFUQ01CXS7N productive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18924 JY8QFUQ01CX9NA unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*05 F 948 91.93 205/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 1 8 10 X 8.10.X [1.17.38.11] CVVDIPEVVWG#FDYW out-of-frame + ctctggattctctttcacttatgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttgcccttattaaaagcaaaactagtggtgggacaacacactacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcagagaacacgttctatctacaaatgaatagactgaaaaccgaggacacagccgtgtattattgtgtcgtagatataccagaagttgtgtgggggaatttgactactggggccagggagccctggtttccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18925 JY8QFUQ01BN711 productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.49 197/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtCgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18926 JY8QFUQ01ASSCV productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18927 JY8QFUQ01CT3GZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 775 84.02 184/219 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [2.17.38.11] CARDSALFGYARYDAMDAW in-frame - Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) gcctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +18928 JY8QFUQ01C8PAO unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18929 JY8QFUQ01DCRUB productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 937 92.24 202/219 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARDQSLGMPEAFDIW in-frame - gcctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18930 JY8QFUQ01BB35T productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 875 89.72 192/214 nt 88.79 190/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARELGGSGTCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 121 to 121 in the user submitted sequence), (cause frameshift); tggatacaccttcaccaggcactatatgcactgggtgcganaggcCccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccGggggcanagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18931 JY8QFUQ01AOWMN productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1077 99.09 218/220 nt 97.27 214/220 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [2.16.38.11] CARDFFIGGYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 42 of V-REGION: 'GT' (2 nucleotides at position 45 to 46 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) cagcctctggattcaccGttcagtagGctatagcatgaactgggGTccggccaggctccagggaagggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18932 JY8QFUQ01AENJP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18933 JY8QFUQ01BDHSG productive (see comment) Homsap IGHV1-18*01 F 957 94.39 202/214 nt 93.93 201/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [0.17.38.11] CATSDVGARKFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggttacacctttaccagatatggtattagttgggtgcgacaggCcccctggacaagggcttgagtggatgggatggatcagcgtttccaatggtgacacaaactatgcacagaagctccagggcagagtcaccatgaccgcagacccatccacgagcacagcctacttggaactgaggagcctgacatctgacgacacggccgtatattactgtgcgacatctgacgttggagctcgaaagtttgactactggggccagggaacccaggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctccgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18934 JY8QFUQ01CU0DA unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F (see comment) 541 71.69 157/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (71,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ggttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18935 JY8QFUQ01BBID5 productive Homsap IGHV4-34*10 F 818 86.98 187/215 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccaagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18936 JY8QFUQ01B7Q12 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 962 94.42 203/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [0.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18937 JY8QFUQ01CHBIN unproductive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1110 100.0 223/223 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFLDY## out-of-frame + ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttactttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18938 JY8QFUQ01BK2WO No results +18939 JY8QFUQ01C8CBF No results +18940 JY8QFUQ01CZDFF productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 815 86.24 188/218 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-3*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARILTLFAVVTSSGMDVW in-frame - Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) ctctgggatttaccttcagtaattatgacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatcaccagtagtggtagttatgtctaccattcagactcaacgaagggccgattcaccatctccagagacaacgcccagaattcactatttctgcaaatgaacaacctgagacccgaggacacggctatatattactgtgcgaggatcctgacgctttttgcagtggttacctccagtgggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18941 JY8QFUQ01CQ5SW productive Homsap IGHV3-66*02 F 813 86.92 186/214 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-10*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARVRFGPSYLDVFDIW in-frame + ctctggattcaccgtcaatagttatcacatgagttgggttcgccaggctccagggaaggggccggagtgggtctcaattatttatccggatggtgacgcattctacgcagactccgtgaagggccgattcaccttctccagagacatttccaagaacacggtgtatctccaaattaacagagtgacaactgaggacacggctatgtactactgtgcgagagtccggttcgggccaagttatctggatgtctttgacatctggggccaagggacattggccaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18942 JY8QFUQ01CJ40J productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 845 88.37 190/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [1.17.38.11] CTRGRSDAWELSDHW in-frame + tcgacgatgggtcctgcagaaactgcttctggagttggatccgccagtccccagggaaggggctggagtggattggggaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagtcgagtcaccatatcattagacacgtccaacaaccaagtctccctgaggttgagctctgtgaccgccgcggacacggctgtgtattactgtacgcgagggcgatccgacgcgtgggaattatcggaccactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +18943 JY8QFUQ01A2FPR unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 895 90.32 196/217 nt 89.4 194/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD5-18*01 F 1 7 8 X 7.8.X [1.17.38.11] CANELGYCSGR## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) cctctggattcaccttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggantgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaAagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtcggggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18944 JY8QFUQ01DF8SK No results +18945 JY8QFUQ01CJ3EX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1000 95.43 209/219 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [2.17.38.11] CARLCGNDCRNDVFDIW in-frame - gcctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18946 JY8QFUQ01B0WOE unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 985 95.37 206/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found tctggattcaccttcaataactataacatgaactgggtccgccaggctccagggaaggggctggagtggatctcatccattagtagtggtagtaatgacataaactacgcagactcagtgaggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggtcggtgccgcaaccaaagtactacggtatggacgtctgggggccaagggaccacggtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18947 JY8QFUQ01C1I0C No results +18948 JY8QFUQ01DLYDH productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18949 JY8QFUQ01BUW1C No results +18950 JY8QFUQ01BTZ0V productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1043 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaaccccttcctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18951 JY8QFUQ01B90VX No results +18952 JY8QFUQ01C310D productive Homsap IGHV4-61*06 ORF, or Homsap IGHV4-61*07 F 865 88.58 194/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD5-18*01 F 3 10 7 17 10.7.17 [2.17.38.11] CAGEQMIDAVSHNYAMDVW in-frame - gtctcctggtggctccatcagcatcaatacttacttctggagttggatccggcagcccccagggaagggactggagtggattgggtatatctctcacagtgggagtgccaactacaacccctccctcgagagtcgagtcaccatcttaagagacacgtccaagaaccagttctctctgaggctgagggctgtaaccgcggcggacacggccgtgtatttctgtgcgggggaacagatgattgacgcagtctcccacaactatgccatggacgtctggggccaagggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +18953 JY8QFUQ01DJHRX unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18954 JY8QFUQ01B25XE productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18955 JY8QFUQ01A05F1 unproductive Homsap IGHV3-7*01 F 879 91.0 192/211 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 2 7 8 X 7.8.X [X.17.38.11] CAKRFLR#AFDLW out-of-frame - attcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagccgaggacacggctgtctattattgtgcgaaaagatttttacgtacgcctttgatctctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18956 JY8QFUQ01A7RE2 No results +18957 JY8QFUQ01A5I8W productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaactctggtcaccgttacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18958 JY8QFUQ01CQSIX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.74 200/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggGggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccagttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18959 JY8QFUQ01A9NYV productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 752 90.66 165/182 nt 90.11 164/182 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 8 15 8.8.15 [1.5.38.11] CARESGAGISAVEFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 43 of V-REGION: 35 nucleotides (from position 42 in the user submitted sequence), (cause frameshift) ctctggattcacctttgataattattggatgagctgggtccaccattaggcgcgatggaggtcagaaatactatgtggactctgtgaagggccgattcatcatctccagagacaacgccaagaagtcactgtttctgcaattgaacagcctgacagccgaggacacggctgtatattactgtgcgagagagtctggggccggaatttctgcggtggagtttgactattggggccagggaactgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtg +18960 JY8QFUQ01BGDRW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 915 90.5 200/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [2.17.38.11] CAKDQSCIVGPCGFDYW in-frame - cagcctccgaattatccttnagcagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18961 JY8QFUQ01DO320 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 775 84.02 184/219 nt 83.56 183/219 nt Homsap IGHJ3*02 F (see comment) 142 76.0 38/50 nt Homsap IGHD1-1*01 F 3 8 8 17 8.8.17 [2.16.38.11] CAKDIWAREWNDMAAFQMW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift) cgcccccggaatcacttttcccagctatgtcatgagttgggtccgccaggcccagggaaggggctggagtgggtcgcaagcattagtgccaggggcgacagttcatactacgcagactccgtgaagggccgattcaccatctccagggacaatcccaggaccacattgtatctggaaatgaacagtctgagagtcgaagacacggccacatattattgtgcgaaagatatctgggcgcgagagtggaacgacatggcggcttttcagatgtggggccaggggacacttgtcattgtctcgtcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18962 JY8QFUQ01BFZOR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cctctggattcacttttaggagtcatatgatgagttgGggtccgccagactccagggaaggGggctggaatgggtctcaagtattcgagccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaactccaagaacacgatgtatttgcaaatgcacagcctgagagtcgacgacacggccgtatactactgtatgaacgaactcggatattgtagtggtggggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18963 JY8QFUQ01BO3A8 No results +18964 JY8QFUQ01B98OJ No results +18965 JY8QFUQ01A4ZZR productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18966 JY8QFUQ01CZMSS productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 169 82.0 41/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDSG in-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgattctgggggcccagggacagtggtcatcgtctcttcatcctccaccaaggggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18967 JY8QFUQ01CZUEE productive (see comment) Homsap IGHV3-7*01 F 950 93.12 203/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'GA' (2 nucleotides at position 21 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGAattcattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18968 JY8QFUQ01BHP64 No results +18969 JY8QFUQ01CCJWA unproductive Homsap IGHV3-48*02 F 896 90.37 197/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-12*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGQKVATSAS#WFDSW out-of-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaagtggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +18970 JY8QFUQ01CNIPU No results +18971 JY8QFUQ01BDSWW No results +18972 JY8QFUQ01AELLN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 960 93.18 205/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKGIVGDTFFDYW in-frame - agcctctggattcacctttagtaattatgccctgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggaatcagtagtagtggtgagatcccaaactacgcagactccgtgaagggccggttcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaaagggatagtgggagacactttctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18973 JY8QFUQ01CCC3L unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDLFQVSTTYFDY# out-of-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18974 JY8QFUQ01BPKG7 productive Homsap IGHV4-61*02 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18975 JY8QFUQ01CSVD2 unproductive Homsap IGHV4-61*02 F 884 89.14 197/221 nt 88.69 196/221 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD5-24*01 ORF 1 10 7 X 10.7.X [1.17.38.11] CARDFWRFLQFSGLL# out-of-frame + in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgGggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctcctcagcctccaccaagggccctatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +18976 JY8QFUQ01CX6D7 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + cctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccatctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactanttgccccgaaccggtgacggtgtcgtggaactc +18977 JY8QFUQ01AF1K4 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 900 90.78 197/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame - gtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18978 JY8QFUQ01BFTCW unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 299 65.61 103/157 nt 8 8 X 8.8.X [1.17.17.X] null - No rearrangement found Low V-REGION identity (65,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatatgaacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18979 JY8QFUQ01BNVDS unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 82 51.09 70/137 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found stop codons cctctggattcacttttagcagccatatgatgagttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccga +18980 JY8QFUQ01AQKIG productive (see comment) Homsap IGHV3-7*01 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcgtctttactaatcattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggGggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18981 JY8QFUQ01AVVU5 No results +18982 JY8QFUQ01BMH9V No results +18983 JY8QFUQ01BGQ8J unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 811 85.84 188/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [2.17.38.11] CMNEFGYCSGG# out-of-frame - ggctctggattcatgttcggtagttatagtctgaattgggtccgccaggctccagggaaggggctggaatgggtcgcaagtattcgtgccagtggtggtaggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgttgtatttgcaaatgtacagtctgagagtcgaggacacggccttatattattgtatgaacgaattcggatactgtagtggtgggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18984 JY8QFUQ01CB7YY unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 719 85.28 168/197 nt 84.77 167/197 nt 8 2 X 8.2.X [1.17.37.X] null - No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) tctgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18985 JY8QFUQ01CADY5 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 729 81.57 177/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18986 JY8QFUQ01BY7RG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt 99.54 216/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); ctctggatTtcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18987 JY8QFUQ01DIYNE productive Homsap IGHV3-7*03 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18988 JY8QFUQ01C8C14 productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaactcag +18989 JY8QFUQ01C0CS5 productive (see comment) Homsap IGHV4-4*07 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [1.17.38.11] CARGKDYYDSTGSLEDGLDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); tctctggtggctCccctcagtacttactactggaactgggtccggcagcccgccgggaagggactggagtggattgggcgtaaatatcccagtggggacaccaactataatccctccctcaaaagtcgagtcaccatgtcactagacacgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagagggaaggattactatgatagtactggttccctcgaggatggtcttgatatctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18990 JY8QFUQ01C3J26 No results +18991 JY8QFUQ01A29EP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1085 100.0 218/218 nt 99.54 217/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcGtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +18992 JY8QFUQ01BJXZ2 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccagGgggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca +18993 JY8QFUQ01CPI0G productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt 88.69 196/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcCccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +18994 JY8QFUQ01C1TBJ productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1073 98.64 218/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARDRGPSSSSKMEYDYW in-frame - tctctggtggctccatcaacagtggtggttactactggagttggatccgccagcacccagggaagggcctggagtggattgggtacatctattacagtgggagtacctactacaacccgtccctcaagagtcgagttaccatatcagtagacacgtctaagaaccagttctccctgaagctgagctctgtgactgccgcggacacggccgtgtattactgtgcgagagatcggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18995 JY8QFUQ01BN9JD unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CTREVGATDY## out-of-frame - tctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +18996 JY8QFUQ01C4ZLK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARDRSGQAVGYW in-frame + cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +18997 JY8QFUQ01CQJZW No results +18998 JY8QFUQ01BBF82 productive (see comment) Homsap IGHV3-7*01 F 830 87.38 187/214 nt 85.98 184/214 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 7 8 12 7.8.12 [0.17.38.11] CVRDRPGGWALDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'TG' (2 nucleotides at position 55 to 56 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift) ctggattcagttttagtgacttttgatgcactgggtccgccaggcnccagggaaTGggggctggagtgggtggGcccacntgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +18999 JY8QFUQ01CV195 unproductive Homsap IGHV3-7*01 F (see comment) 742 82.87 179/216 nt 82.41 178/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.37.11] CARLKGLTHR##FYFDLW out-of-frame + Low V-REGION identity (82,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 111 in the user submitted sequence), (cause frameshift) ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttgggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcgacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +19000 JY8QFUQ01DWZBA productive (see comment) Homsap IGHV3-11*01 F 973 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [2.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); agcctctggcttcaAccttcagtgactactacatgaactgggtccgccaggctccagGggaaggggctggantgggtttcatacattagtggaagtggaactaccatatcctacggagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtatctccagatgaacagcctgagagccgaggacacggccgtatattactgtgtgaggcgggtgtggggatacagctatggttccgtctcgtactattttgagtactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19001 JY8QFUQ01CAVGN No results +19002 JY8QFUQ01CVQ6B productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F (see comment) 770 82.38 187/227 nt 81.94 186/227 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 10 13 8.10.13 [2.17.38.11] CSTGGPNGYHSTYPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'AA' (2 nucleotides at position 28 to 29 in the user submitted sequence), (cause frameshift); aggcctctggattcgccttcaatatcgAAgtgggatgagttgggtccgccaggctccggggaaggggcttgagtgggtcggccgcatcaagagcagcgctgatggtgcgacaacagacaccattgagcgcgtgagagacagattcaccatctcaagagatgactcaaaaaatacactgtacttgcacatgaccagcctgagaaccgaggacacaggcatgtattattgttccacaggcgggccaaatggatatcactccacatatccctggggcccggggacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19003 JY8QFUQ01DKKJ0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 797 85.32 186/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKVWIELWSAGDHFDNW in-frame + cctctggattcatatttactagatatgccatgacctgggtccgccaggctccagggaagggtctggagtgggtcgcttctatcagtggtagtgggattagtaaaaagtacgcagacggcgtggagggccgattcaccatctccagagacagttccgagagaacactgtatctacaaatgaacagcctgagagtcgaggacacggccacatattattgtgcgaaagtatggatagagttatggtcggctggggaccactttgacaactggggccagggaaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19004 JY8QFUQ01CIVNC unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19005 JY8QFUQ01BGEYK productive (see comment) Homsap IGHV3-11*01 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ6*02 F 263 94.83 55/58 nt Homsap IGHD1-26*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDYYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'GGG' (3 nucleotides at position 97 to 99 in the user submitted sequence), (do not cause frameshift); gcttctgggttctccttcagcgactacttcatgagttgggtccgccaggctccagggaagggactggagtgggttgcatacattagtagtagtggtGGGactactaaatactacgcagactctgtgaagggccgattcaccatctccagggacaacggcaagaattcattgtttctgcaaatggacagcctgagagtcgacgacacggccatgtatttctgtgtgagagactactattattacgggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19006 JY8QFUQ01BSNEY No results +19007 JY8QFUQ01AFUVE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19008 JY8QFUQ01CNC53 unproductive Homsap IGHV3-7*01 F 1022 96.79 211/218 nt 96.33 210/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSGFYSTGY## out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGcctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19009 JY8QFUQ01BPY0E No results +19010 JY8QFUQ01DH30S productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 977 94.5 206/218 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD3-22*01 F 3 9 7 11 9.7.11 [1.17.38.11] CAGLLTTFGLQSW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcagcagtagtaactggtggacttgggtccgccagcccccagggaaggggctggagtggattggggaaatctatcatggtggaaacacctactacaacccgtccctcaagagtcgagtcaccatatcactagacaagtccaagaaccaattctctctgaacctgaactctgtgaccgccgcggacacggccatatattactgtgcgggacttcttacgacttttggactgcagagctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19011 JY8QFUQ01BJS80 No results +19012 JY8QFUQ01C3CHE productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19013 JY8QFUQ01DE6QR unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 955 93.15 204/219 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [2.17.38.11] CVRGGLRWRPRTLLRP#YGLDVW out-of-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagagggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtnttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19014 JY8QFUQ01BRFU0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattctccttcgaggggtctgtcgtgacctgggtccgacaggctccagggaaggggctggagtgggtctcaggtatctacggtggtgatggtacatcattttacgcagacttcgcgaagggccgattcaccgtctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19015 JY8QFUQ01CTEYF productive (see comment) Homsap IGHV3-9*01 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD5-24*01 ORF 3 8 8 17 8.8.17 [1.17.38.11] CVKDRKAGGYNLLDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcaccttcgacgactatgtcatgcattgggtccggcaagttccagagaGggggcctggagtgggtcgcaggcattaatggggaaagtaatagttttggctctgtggactctgtaaagggccgattcaccatctccagagacaaggccaagaataccctgtatttgcaaatgaatagcctgagagttgaggacacggccttgtattattgtgtgaaagatagaaaagctggtggctacaatctgttggatgcttttgatatctggggccaagggacaatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19016 JY8QFUQ01C5MCI productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 891 90.32 196/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - ctctggatcacctttggttattgatggcatgagctgggtccgccaagctccggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19017 JY8QFUQ01COMEW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19018 JY8QFUQ01BRKER unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +19019 JY8QFUQ01CN3XN No results +19020 JY8QFUQ01AJWTG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.37.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 176 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19021 JY8QFUQ01CH10S No results +19022 JY8QFUQ01DC0U0 productive Homsap IGHV3-33*03 F 927 92.17 200/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctcccagccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19023 JY8QFUQ01A5AQS unproductive Homsap IGHV3-30*10 F (see comment) 708 80.45 177/220 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [2.17.38.11] CSRGTTGTTDDSRLFQH## out-of-frame - Low V-REGION identity (80,45% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgcctctggattcagcttcggcaattacgccatgcactgggtccgccaggctccaggcaagggcctagagtgggtggctgtcataaataaggctgggaagactaaacattatatagactccgtgaagggccgattcaacgtctccagagacaactccgaaaaaacactctatttggagatgaataacgtgggagttgaggacacggctgtatattattgttcgagaggtaccacggggacgacagacgactcgaggttgttccaacactgggggccagggcgccctggtcaccgtttcgtcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +19024 JY8QFUQ01BPCP0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 1 8 8 11 8.8.11 [2.16.38.11] CARDGEWEMLDHW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'GG' (2 nucleotides at position 91 to 92 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift) cagcctctggattcacctttaggagctatgccagagctgggtccgccaggctccagggaaggggctgagtgggtctcaactattagtggtGGaatgttgatagcacagactacgcagattccgtgaagggccggttcaccatctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacatatttttgtgcaagagacggggagtgggagatgcttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19025 JY8QFUQ01CEPJM No results +19026 JY8QFUQ01CQD5V No results +19027 JY8QFUQ01BIRKM productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt 99.54 216/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19028 JY8QFUQ01A10TS No results +19029 JY8QFUQ01C930D productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 841 87.96 190/216 nt 87.04 188/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [2.17.38.11] CAREFRAPSLARYGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GAA' (3 nucleotides at position 59 to 61 in the user submitted sequence), (do not cause frameshift); gcctctggattcaccttcagcaaccataacatgacctGgggtccgccaggttcccaggGAAagggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19030 JY8QFUQ01CC0K4 productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19031 JY8QFUQ01AWYMJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19032 JY8QFUQ01AJVOK productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDPFIAATGRPWYFEYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagcagctatggcatgcactggttccgccaggctccaggcaaggggctggagtgggtggcagctatctcatatgatggaattgacaaatattatgcagactccgtgaagggccgattcaccatctccagagacaatgccaaaaaGcacgctgtatctgcaattgaacagcctgagaagtgaagacactgctgattactactgtgcgaaagacccatttatagccgcaactggccgcccctggtactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct +19033 JY8QFUQ01BAFCP unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt 92.86 208/224 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD2-2*01 F 1 8 7 X 8.7.X [4.17.38.11] CARGAPVFM#*C out-of-frame + in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); cctctgcagcctctggattcattgtcaatagcaactacatgagttGgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccagttttcatgatagtgttaaaggggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19034 JY8QFUQ01A51OR unproductive Homsap IGHV4-4*07 F 850 88.43 191/216 nt Homsap IGHJ3*02 F 160 80.0 40/50 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [2.17.38.11] CAGRNGNLA#FYIW out-of-frame - gtatctggtggttcgatcgtcagttactactggagttggatccggcagtccgccgggaagggactggagtggattgggcgcatctactccaatggggatacgaactacaatccctccctcaagggtcgagtcaccatgtcagtagacccttccaacaaccagttctccctgaggttgagttctgtgaccgccgcggacacggccgtatattactgtgcgggaagaaatggaaatttggcccttttatatctggggccaagggacgactgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19035 JY8QFUQ01C28WK productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 875 88.24 195/221 nt 87.78 194/221 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARQRYYESDGQTW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaccggaagtagttattattggggctggattcgccagTcccccagggaaggggctggagtggattggaagtatgtattacactgggagcaccgactacaacccgtccctcaagagtcgggtcacgatatccgcagacaagtcgaagagccaggtctacctgaagttggactctgtgaccgccgcagacacaggtgtttattactgcgcgagacaaaggtactatgaaagtgatggccaaacctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19036 JY8QFUQ01A9O5T productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 908 91.63 197/215 nt 90.7 195/215 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-13*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARGVGQQLPPLDW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctcgtggctccatcactccttcctactgGgagctggatccggcagAcccccagggaagggactggagtggattggatatatctatgacagtgggagtaccaagtacaacccctccctcaagagccgagtctccatatcaatagactcgtccaagaaccagttctccctggagctgttctctgtgaccgctgcggacacggccatatattactgtgcgagaggggtggggcagcaactgccccccttagactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19037 JY8QFUQ01APLRK productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 7 21 8.7.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19038 JY8QFUQ01C2V90 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 106 55.77 58/104 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons ctctggattcaccttcagtcgttatagcatgaactgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19039 JY8QFUQ01CCCYD productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame - tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19040 JY8QFUQ01AEF6H unproductive (see comment) Homsap IGHV3-48*02 F 597 94.74 126/133 nt 93.98 125/133 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 88 64.0 32/50 nt Homsap IGHD3-3*01 F 2 8 X X 8.X.X [1.11.24.11] CARARRTISGVGFY*ALRYGRL# out-of-frame - stop codons in FR2-IMGT, from codon 50 of V-REGION: 84 nucleotides (from position 62 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcaggacccatagcatgaactgggtccgccaggctccagggaagggagacaatgccaagaactcactttatctgcaaatgaacagcctgagagacgaggatgcggctgtgtattactgtgcgagagcccgtaggacgatttctggagtgggtttttattgagcactacggtatggacgtctgggggcccagggaccacggtctccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19041 JY8QFUQ01BMLX4 productive Homsap IGHV4-61*02 F 870 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + ttccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccttgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19042 JY8QFUQ01BFQYX productive Homsap IGHV2-5*02 F (see comment) 858 84.23 203/241 nt Homsap IGHJ4*01 F 195 89.58 43/48 nt Homsap IGHD1-1*01 F 2 10 7 11 10.7.11 [8.17.38.11] CARIGRLEHFDSW in-frame - Low V-REGION identity (84,23% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcacgctgacctgtaccgtctctggcttctcgctctccactcctggcgtgggcgtggcctggctccgtcagtccccaggagaggccctggagtggcttgcactcatttactgggatgatgatagccgctatagcccatctctgaaggacagactcaccatcaccaaggacacctccgaaaaccttgtggtcctgacactcagcgacatcgatacagtggacatcgccacatatttttgtgcacgcataggccgtctggaacactttgactcctggggccaaggaatactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19043 JY8QFUQ01DAFAO productive (see comment) Homsap IGHV3-48*01 F 1013 96.33 210/218 nt 95.87 209/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDQSPGVAVAGPDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagatatagtatgaactgggtccgccaggctccaggaaaggGggctggagtgggttgcatacattagaagtagcagtagtgtcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcaaagtccgggtgtagcagtggctggtcctgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19044 JY8QFUQ01DV5MY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 838 87.21 191/219 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARLRSFGDYPLDVW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19045 JY8QFUQ01CZTNE unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt +19046 JY8QFUQ01CMXNJ productive (see comment) Homsap IGHV4-61*02 F 875 88.69 196/221 nt 88.24 195/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); tctctggtggccCccatcagcagcagcacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttccc +19047 JY8QFUQ01AZUQ0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19048 JY8QFUQ01CQW74 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcaccttcaataactataacatgaactgggtccgccaggctccagggaaggggctggagtggatctcatccattagtagtggtagtaatgacataaactacgcagactcagtgaggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggtcggtgccgcaaccaaagtactacggtatggacgtctggggccaaagggaccacggtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +19049 JY8QFUQ01B5056 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19050 JY8QFUQ01BX3O1 No results +19051 JY8QFUQ01AD7SL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 91 71.05 27/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcatgtttagtagctttccccatggcctgg +19052 JY8QFUQ01B2RIE productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 973 92.11 210/228 nt 91.67 209/228 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [2.17.38.11] CARGGNYYDSGGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); tctccgggggacagtgtctctagcagcagtgttgTtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcgaataactatcaagccagacgcatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtatattactgtgcaagagggggtaattactatgatagtggtggtcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19053 JY8QFUQ01CQHDY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 937 91.78 201/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - gcctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19054 JY8QFUQ01B7VPL unproductive (see comment) Homsap IGHV3-7*01 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [0.17.38.11] CVRG*RWCQFWRN#DYW out-of-frame - stop codons in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctgggttcatctttagtagacattggatggcctgggtccgccaggctccagGggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgagggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19055 JY8QFUQ01A5WKX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19056 JY8QFUQ01BV0L0 productive (see comment) Homsap IGHV3-7*01 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDSPSAYDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGcctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19057 JY8QFUQ01CAT22 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19058 JY8QFUQ01BCOUS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame - cctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggtcagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19059 JY8QFUQ01COKJG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 842 87.61 191/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-8*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDRIGSLYYFDHW in-frame - cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacagcaaaaactccctgtatctgcaaatgaacagtctgagaactgaggacaccgccttgtattactgtgcaaaagataggattgggtccttgtactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19060 JY8QFUQ01B5GFJ productive (see comment) Homsap IGHV3-7*01 F 957 94.39 202/214 nt 93.93 201/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARGSYYYYDTNGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tggatttacctttacaaattattggatgagctgggtccgccaggctccagggaGgggggctggagtgggtggccagcgtaaaacaagatggaggtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggtcctactattattatgatactaatggcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +19061 JY8QFUQ01B5GW8 No results +19062 JY8QFUQ01BXJNH unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*03 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 922 92.13 199/216 nt 91.2 197/216 nt Homsap IGHJ3*02 F (see comment) 124 72.0 36/50 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDEIPWDTIEYYFDY## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 2 nucleotides (from position 97 in the user submitted sequence), (cause frameshift) cctctggattcaccttcactacatattccatgcactgggtccgccaggctccaggcaaGggggctagaatgggtggcagttatatcatatgatggaaaaaaaatcttatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtacctgcaaatggacagcctgaggcctgaagacacggctgtgtattactgtgccagagatgagatcccttgggatacaatagagtactactttgactactgggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19063 JY8QFUQ01DA8OU productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 970 93.24 207/222 nt 92.79 206/222 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.37.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 161 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaatatgctgtatctagcattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +19064 JY8QFUQ01A5D26 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 1 8 8 18 8.8.18 [1.17.38.11] CARGEFLL*N*WSKGVFDYW in-frame + stop codons cctctggattcaccttcactacctcctggatgcactgggtccgccaagctccagggaaggggctaatgtgggtcgcacgtattaataaggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaccacactgtacttggaaatggacagtctgagagtcgaggacacggctatgtattattgtgcaagaggggaatttttactatgaaactagtggtcgaagggggtttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19065 JY8QFUQ01CW3TA productive (see comment) Homsap IGHV3-33*03 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [2.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) gcgtctggattGcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19066 JY8QFUQ01CI8VS No results +19067 JY8QFUQ01B9ESA No results +19068 JY8QFUQ01AH5X7 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19069 JY8QFUQ01BA7Y6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtcgacggtgtcgtggcaactca +19070 JY8QFUQ01CE7ZB No results +19071 JY8QFUQ01CYCGV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggGggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtggggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19072 JY8QFUQ01ALYZC productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 751 83.33 180/216 nt 82.87 179/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 19 8.8.19 [1.17.37.11] CTRGSSRGGRYDENYYELDFW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 82 of V-REGION: 2 nucleotides (from position 151 in the user submitted sequence), (cause frameshift) cctctggattccccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaggggccgattcaccatccccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19073 JY8QFUQ01B1S8U No results +19074 JY8QFUQ01AVAD8 productive (see comment) Homsap IGHV4-39*02 F 803 85.07 188/221 nt 84.62 187/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD2-2*01 F 3 10 7 15 10.7.15 [1.17.38.11] CASVGGRDTSGNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'CT' (2 nucleotides at position 75 to 76 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagtcatagtgcttactactgggcctggatccgccagcccccagggaaggggctggagCTgggattgggaatatcaataacaatggaaaaactcactacaatccgtccctcaagagtcgagtctccatgtccctggacatgtccacggaatccttctccctggagctgacctctgtgaccgccgaagacacggcagtgtattactgtgcgagtgtagggggacgagatacaagtggcaattggttcgacccctggggccaaggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19075 JY8QFUQ01BT7QY productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 769 84.26 182/216 nt 83.8 181/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.37.11] CARDSALFGYARYDAMDAW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 123 in the user submitted sequence), (cause frameshift) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgagggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +19076 JY8QFUQ01B6OHM unknown (see comment) Homsap IGHV4-61*01 F 983 94.12 208/221 nt 93.21 206/221 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 36 of V-REGION: 'CT' (2 nucleotides at position 28 to 29 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'TATAATCCCCTG' (12 nucleotides at position 113 to 124 in the user submitted sequence), (do not cause frameshift); tctctggtggctccgtcagcagagataCTtttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatgtatcacagagggaacactaagTATAATCCCCTGtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19077 JY8QFUQ01CEX28 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 941 92.66 202/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - ctctgggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19078 JY8QFUQ01DFSD4 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19079 JY8QFUQ01BYLWM productive Homsap IGHV3-23*03 F (see comment) 522 71.43 155/217 nt Homsap IGHJ2*01 F 166 79.25 42/53 nt Homsap IGHD3-3*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARVRNSNWYFDHW in-frame + Low V-REGION identity (71,43% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgaagacatgtttaagagtttcggattgacgtgggtccgtcaggctccagggaaggggctggagtgggtcgcaggaataaacaattacaatggtgcaactttctatgctggccccgtaaagggccgcttcaccgtctctcgagataaagaaaagaccattttttatctacaaatggacaacgtgagggtcgacgacacgggcgtttatttctgtgcgagagtcaggaatagtaattggtacttcgaccactggggccgcggcgcactagtcacagtctccgcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgccctggtccagggcttcttccccca +19080 JY8QFUQ01B2K9Y productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 863 89.3 192/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + ttcgggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19081 JY8QFUQ01BCLGV No results +19082 JY8QFUQ01B3TEJ productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 989 93.75 210/224 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 2 8 10 16 8.10.16 [1.17.38.11] CAADGCPGGTCYHGFDMW in-frame + cctctggattcactttcagtaacgtctggatgcactgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgctggtggggcaacagaatacgctgcgcccgtgagaggcatattctccatctcaagagatgattcaaagaacacgttgtatctgcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtgccgcagatggttgtcctggtggtacctgctatcatggttttgatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +19083 JY8QFUQ01BT7VZ unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CAREKGSGPPH#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +19084 JY8QFUQ01CPYLJ productive (see comment) Homsap IGHV3-7*01 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); tctctggattcaccGtttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19085 JY8QFUQ01CKAP3 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 824 86.7 189/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + stop codons cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgagtctcattcgttaatagtggaagtagttacatctactacgcagactcagtaaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19086 JY8QFUQ01AVX7B productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 788 84.86 185/218 nt 84.4 184/218 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'ACAGTG' (6 nucleotides at position 19 to 24 in the user submitted sequence), (do not cause frameshift); tctctggtggctccatcaACAGTGgtagttatcactgggcctggatccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19087 JY8QFUQ01BFHKO productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 932 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame - Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19088 JY8QFUQ01DJL6V productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD5-24*01 ORF 3 10 7 14 10.7.14 [1.17.38.11] CARRGDADNYWYFDLW in-frame - tctctagtgactccatcagcagtactaattactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatgtatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgagacggggagatgcggataactactggtacttcgatctctggggccgtggcaccctggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19089 JY8QFUQ01ASM74 unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19090 JY8QFUQ01BTZDX unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGEFLL*N*WSKG#FDYW out-of-frame + stop codons ctctggattcaccttcactacctcctggatgcactgggtccgccaagctccagggaaggggctaatgtgggtcgcacgtattaataaggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaccacactgtacttggaaatggacagtctgagagtcgaggacacggctatgtattattgtgcaagaggggaatttttactatgaaactagtggtcgaaggggtttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccag +19091 JY8QFUQ01AS9TS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt 86.64 188/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 1 8 8 16 8.8.16 [1.17.38.11] CTKDPQQLLEGVNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctctggattcacctttaggagctatgccatgagttgggtccgccaggGctccagggaaggggctagagtgggtctcgtctatcagtggcagtggtgataagacaaagtatgcagattcagtgaggggccggttcaccatctccagagacaattacgacaacacattatatctgcgaatggagggcctgagagccgaggacacggccacatattactgtacgaaagatcctcagcaactgttggaaggggtaaattggttcgacccctggggccagggaaccctggtcaaggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19092 JY8QFUQ01AR5WV productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19093 JY8QFUQ01CU9PB unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 902 90.05 199/221 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found cagcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19094 JY8QFUQ01AWJP4 No results +19095 JY8QFUQ01CG8C8 unproductive Homsap IGHV3-7*01 F (see comment) 698 80.28 175/218 nt 79.36 173/218 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CARLKGLTHHDFYFDL## out-of-frame - Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); cctctggattcgtctttactaatcattggatgagttgGggtccgccaggccacagggaaggggccggagtgggtggccaacatatcccccagacggaatacgaaatattttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctgggggccgtggcaccctggtcactgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19096 JY8QFUQ01BOYQG productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19097 JY8QFUQ01CLTMY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19098 JY8QFUQ01AH0R7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19099 JY8QFUQ01BVK09 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [1.17.38.11] CAKEGNLGYFDDW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19100 JY8QFUQ01BK1SN unproductive Homsap IGHV4-4*07 F, or Homsap IGHV4-59*10 F 800 86.05 185/215 nt 83.72 180/215 nt Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD3-3*01 F 3 8 7 X 8.7.X [1.17.38.11] CARCPNYNIGTRGFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'GAGTCC' (6 nucleotides at position 24 to 29 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'CG' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); tttctggtgtctccatgagcaatGAGTCCtattactggacgtggatccgGgcagcccCGtcggggaaggggAccggagtggattgggcgcatctacaccagtgGggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19101 JY8QFUQ01B8SCQ productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 737 82.79 178/215 nt 82.33 177/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtcaatcaaTagagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19102 JY8QFUQ01BMDEC unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD1-26*01 F 1 7 8 X 7.8.X [1.17.38.11] CARSGSGSHLDY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) tctctggattcaccGtttagtaggtttggatgacctgggtccgccagggtccagggaaGggggctggagtgggtggccaacataaAagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19103 JY8QFUQ01A181R productive (see comment) Homsap IGHV1-18*01 F 867 89.72 192/214 nt 88.32 189/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-10*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARVIRTNWLDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'GGC' (3 nucleotides at position 25 to 27 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tggttacacctttaccTacctatgGGCgtcaccctggggtgcgacaggCcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggtaatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacagccgtatattattgtgcgcgagtgattcggaccaactggctcgacccctggggccagggaacactggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19104 JY8QFUQ01AYFYW productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19105 JY8QFUQ01CA7PU productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [0.17.38.11] CATSDVGARKFDYW in-frame + tggttacacctttaccagatatggtattagttgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcagcgtttccaatggtgacacaaactatgcacagaagctccagggcagagtcaccatgaccgcagacccatccacgagcacagcctacttggaactgaggagcctgacatctgacgacacggccgtatattactgtgcgacatctgacgttggagctcgaaagtttgactactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +19106 JY8QFUQ01AH5A1 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.16.38.11] CARHGSGWLQELDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtggctGccatcatcagagacagtgcctactggggctggatccgccagccccagggaaggggctggagtggcttgggagcatctattatagtgggagtacctactacaatccctccctcaagagtcgagtcaccatatccgtagacacgtccaagaagcagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagacatggcagtggctggctccaggaacttgactactggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19107 JY8QFUQ01C2H93 productive Homsap IGHV3-30*01 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVGDSSRPRGPFNYW in-frame + cctctggattcaacttcaatggctttaatatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttttgtcatatgatggaaataataagttctacgcagactccgtgagtggccgattcaccatctccacagacagttccaagaggacattgtttctgcaaatgaacaacctgacaactgaagacacggctctttattactgtgtgggggacagtagccggccccgggggccttttaactactggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +19108 JY8QFUQ01BHOG6 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 940 93.06 201/216 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [2.17.38.11] CARAPRTATLLDPW in-frame - gtctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19109 JY8QFUQ01CPPN6 productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +19110 JY8QFUQ01BX7KN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 149 89.19 33/37 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found tctctggattcacctttgacagctacgccatgagctg +19111 JY8QFUQ01CMRHA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [1.17.38.11] CANEVGYCSG## out-of-frame + ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +19112 JY8QFUQ01CW7IR productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 831 89.76 184/205 nt 88.78 182/205 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.37.11] CARHPKSNVEGDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 9 nucleotides (from position 14 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 70 of V-REGION: 1 nucleotides (from position 107 in the user submitted sequence), (cause frameshift) tctctggtgactcccacttctggagctggatccggcagcccccgggaaagggcctggagtggattggttatgtctataacagtgggaccaccaactacaacccctcctcaggagtcgagtcaccatgtctatagacacgtccaagaagcagatctctctgaggttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactcctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19113 JY8QFUQ01CVRLS productive (see comment) Homsap IGHV4-4*07 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgCaaaactctaactacaaTcccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19114 JY8QFUQ01B9X5T productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19115 JY8QFUQ01AEPNF unproductive Homsap IGHV3-30*01 F 873 89.4 194/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CACGHMRDGYDV## out-of-frame - ctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctgggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19116 JY8QFUQ01BPEHO unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 674 94.04 142/151 nt 8 8 X 8.8.X [1.17.16.X] null + No rearrangement found ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaat +19117 JY8QFUQ01BUXJ7 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19118 JY8QFUQ01A3QD4 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19119 JY8QFUQ01B7OTL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 995 95.41 208/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame + cctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +19120 JY8QFUQ01BZVFM productive Homsap IGHV3-48*03 F 865 88.58 194/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDKGWSGYGMDVW in-frame - gcctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19121 JY8QFUQ01CMP5A unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt 8 7 X 8.7.X [4.17.38.11] CARGAPFS** (see Functionality comment) out-of-frame + stop codons, IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19122 JY8QFUQ01CMMMF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19123 JY8QFUQ01B9RLH productive Homsap IGHV2-5*02 F 1170 97.95 239/244 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 2 10 7 11 10.7.11 [9.17.38.11] CAHRRIRFGFDYW in-frame + gaccctcacgctgacctgcaccttctctgggttctcactcagcactggtggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcactcatttattgggatgatgataagcgctacagcccatctctgaagagcagactcaccatcaccaaggacacgtccaagaaccaggtggtcctcacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacaggaggatacgattcggctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +19124 JY8QFUQ01BBSUJ No results +19125 JY8QFUQ01BM3Q0 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); ctctggattcaTcgttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaataCcgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19126 JY8QFUQ01C3T5I unknown (see comment) Homsap IGHV3-48*03 F 810 86.18 187/217 nt 85.71 186/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found stop codons in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); ctctggattcacctttactagttaCagttttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctgggccagggaaccctgtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc +19127 JY8QFUQ01CCGC0 No results +19128 JY8QFUQ01AE9BM No results +19129 JY8QFUQ01BC03T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgagagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19130 JY8QFUQ01DIARZ productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19131 JY8QFUQ01DD50U unproductive Homsap IGHV4-61*02 F 870 88.64 195/220 nt 88.18 194/220 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD2-2*01 F 3 10 7 X 10.7.X [1.17.38.11] CARERSSSSGGTRELDS## out-of-frame + in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); ctctggtggccccatcagcagtggtgcttactactggacctggatccggcagcccgccgggaaggggctggagtggatcggacgggtttatagaagtgGggtacaccgactacaatccctccctcaagagtcgagtcaccatgtcactagacgcgtccaatgaccagttctccctgaggttgaactctgtgaccgccgcagacacggccgtatattactgtgcgagagaacgtagtagctcgagtggcggaacgagagaacttgactcctgggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19132 JY8QFUQ01COTZA unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 984 95.79 205/214 nt 95.33 204/214 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [0.17.38.11] CASAPSDSSGYYFSY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagttactatatgcactgggtccgacaggcccctgGgacaagggcttgagtggatgggaatgatcaaccctagtggcggaagcacaatctacgcacagaacttccagggcagagttgccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgctagcgccccctctgatagtagtggatactacttttcctactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag +19133 JY8QFUQ01B3XIV unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 282 84.62 66/78 nt 8 X X 8.X.X [1.16.X.X] null + No rearrangement found Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcatttttagaaattttgccatgagttggctccgccaggcaccagggaaggggctggaatgggtctcga +19134 JY8QFUQ01CZ4RG productive Homsap IGHV3-64*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + cctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19135 JY8QFUQ01CTA39 No results +19136 JY8QFUQ01BFRWU unproductive Homsap IGHV3-48*01 F (see comment) 754 84.04 179/213 nt 83.1 177/213 nt Homsap IGHJ1*01 F 89 63.46 33/52 nt Homsap IGHD5-12*01 F 1 8 7 X 8.7.X [1.17.38.11] CSRDGRRGYDLDS## out-of-frame - Low V-REGION identity (84,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 82 in the user submitted sequence), (do not cause frameshift) tctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtGgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagcccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19137 JY8QFUQ01CGONG productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1038 96.41 215/223 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 10 17 8.10.17 [1.17.38.11] CTRDNPPLRSLEWLPFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ttctggattcacctttggtgattatagtatgagttggttccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcaaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +19138 JY8QFUQ01C9OOD productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + ttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19139 JY8QFUQ01CCX7V No results +19140 JY8QFUQ01DTYSW No results +19141 JY8QFUQ01AYEYZ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19142 JY8QFUQ01CM5IQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVKDISRSGCFEYW in-frame + ctctggattccagtttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtccatcgcctgccctggtccagggcttcttcccccc +19143 JY8QFUQ01C231C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGFYGDYPATWFDPW in-frame + ttctggactcacttttagcagccatgccatgagctgggtccgccaggctccagggatggggctggagtgggtctcagcccttaatgatcgtggtgataccacatactacgcggcctccgtgaggggccggttcaccatctccagagacaattccaagaacatgctgtttctacacatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagggcttctacggtgactacccggcgacgtggttcgacccctggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19144 JY8QFUQ01CWJAZ unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 769 82.67 186/225 nt 81.78 184/225 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD5-18*01 F 2 10 7 13 10.7.13 [3.17.38.11] CARHSRLVRYF*ILG in-frame - stop codons Low V-REGION identity (82,67% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); tctctggtggctcccatccaacaaggtggtagttatcactgggcctggatccgccagtccccagggaaAggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtGccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtacttttgaattctgggggccagggagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +19145 JY8QFUQ01CQI78 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARKRVPGGNFLW#DYW out-of-frame + cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggaactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagccacagcggcccttgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19146 JY8QFUQ01B2UAC unknown (see comment) Homsap IGHV3-74*03 F 115 54.92 67/122 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found tctggattcaccttcagtagctactggatgcactgggtccgccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +19147 JY8QFUQ01C96QO No results +19148 JY8QFUQ01DLQGA productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttgggggAcaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +19149 JY8QFUQ01CKRGF productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagGaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19150 JY8QFUQ01BR8YS productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame + gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19151 JY8QFUQ01AXQ9G productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + ctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19152 JY8QFUQ01B1LH3 unproductive Homsap IGHV3-30*01 F 869 88.99 194/218 nt 88.07 192/218 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGVTKARYGLDV## out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'A' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggGggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagAaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctgggggccaagggaccacggtcatcgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +19153 JY8QFUQ01DKLCW productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGDDILSGYSIDTW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cttctggatacactttcaccactcactggatcgcctgggtgcgccagatgcccgggaAaaggcctggcgtggatgggaatcatctttcctggagactctgagactagatacaacccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagtaccgcctacctgcagtggagcagcctggaggcctcggacaccgccatctactattgtgcgagaggggacgatatcttgagtggttattcaattgacacctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19154 JY8QFUQ01C39FU unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-3*01 F 3 8 8 17 8.8.17 [2.17.38.11] CARILTLFAVVTSSGMDVW in-frame - stop codons Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) gcctctggattcacctttagcagccatcccatgagctgagtccgccaggctccagggaaggggctggagtgggtctcatccatcaccagtagtggtagttatgtctaccattcagactcaacgaagggccgattcaccatctccagagacaacgcccagaattcactatttctgcaaatgaacaacctgagacccgaggacacggctatatattactgtgcgaggatcctgacgctttttgcagtggttacctccagtgggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19155 JY8QFUQ01AC0DP productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 920 90.95 201/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-8*02 F 1 10 7 12 10.7.12 [1.17.38.11] CARLTDWWGHFDHW in-frame - tctctggtggctccatcagcggtacttctcattactggggctgggtccgccagcccccagggaaggggctggagtggattggcagtatctactctggtgggaccacctactacaacccgtccctcaagagtcgactcaccatgtccgtcgacacgtccaagaaccagatgtccctgcggctgagctctgtgaccgccgcagacacggctgtctattactgtgcgagactgacagactggtgggggcactttgatcactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +19156 JY8QFUQ01CIZLY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 895 90.74 196/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - tccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19157 JY8QFUQ01BCT8D productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19158 JY8QFUQ01BQWRG unproductive Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaGggggctggagtGgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgaccagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagg +19159 JY8QFUQ01BJVT6 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 186 97.44 38/39 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found cctctggattcatcttcagtagctactggatgcactggg +19160 JY8QFUQ01CZ8KV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [2.17.38.11] CARDNYGDYW# out-of-frame - gcctctggattcacctttagtagttctggcatgtattgggcccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatgccacaaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaggc +19161 JY8QFUQ01ALS49 No results +19162 JY8QFUQ01B3S8M productive Homsap IGHV3-7*01 F 846 88.02 191/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRDRPGGWALDYW in-frame - Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19163 JY8QFUQ01DSY3R unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CANELGYCSGRG# out-of-frame - in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtagtcatgtcatgagctgggtccgGccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaAagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtcgggggggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc +19164 JY8QFUQ01AMMCF No results +19165 JY8QFUQ01BKL8E productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 972 94.47 205/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKSPSQVGYYLDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtaccttTtggcatgcactgggtccgccaggctcccggcaAaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcaccatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19166 JY8QFUQ01ADTZ7 No results +19167 JY8QFUQ01B9ZJQ productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 82.79 178/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-13*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNSLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagccCcccagggaagggactggagtggattgGgggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacagtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19168 JY8QFUQ01BVDHY productive Homsap IGHV3-30*01 F 977 94.5 206/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +19169 JY8QFUQ01C1WET productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactgggaccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactca +19170 JY8QFUQ01B6LHF productive Homsap IGHV3-48*01 F 811 85.84 188/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CATDRLRGDKYNFDDW in-frame - ggctacggatttgtcttcagtggcactaatatgaattggctccgccaggctccagggaaggggctggagtggatttcacacattagtcacaatagtgaaaccatattctatgcagactctgtgaggggccgagtcaccatctccagagacaatgccaggaactcactgtatctgcacatgagcagcctgagagccgaggacacggcagtatattactgtgcgaccgaccgccttcgtggagataaatacaattttgacgactggggccagggaaccctggtcaccgtctccccagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19171 JY8QFUQ01CQ8UD productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.16.38.11] CARAIGRPFYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaagggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19172 JY8QFUQ01BMRSQ productive Homsap IGHV3-48*01 F 1054 98.17 215/219 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD2-21*02 F 3 8 8 9 8.8.9 [2.17.38.11] CARDQVTEDYW in-frame - gcctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccttggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19173 JY8QFUQ01A554Z productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtGacctatggcatgctctgggtccgccatgttgcaggcaaGggggctggagtgggtggcaactatatcagctgatggacgaaatCaaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19174 JY8QFUQ01BR8JQ unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 160 80.0 40/50 nt Homsap IGHD6-25*01 F 3 8 7 X 8.7.X [1.17.38.11] CARGTRYNNGLD#FDVW out-of-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctGggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgctttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19175 JY8QFUQ01B7Y92 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt 91.59 196/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 53 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 97 of V-REGION: 'CG' (2 nucleotides at position 195 to 196 in the user submitted sequence), (cause frameshift); tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggGAaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccCGggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19176 JY8QFUQ01DA6LQ productive Homsap IGHV4-61*02 F 974 93.67 207/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSAPWNDHW in-frame + tctctggtggctccatcagcagcggttattactactggagctggatccggcagcccgccggggagggactggagtgggttgggcgtatctctgccagtggggacaccaactacaacccctccctcaagagtcgagtcaccatatcagtgaacacgtccaagaaccagttctccttgaggctgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagacaaggggacagtagtgctccctggaatgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19177 JY8QFUQ01DLBW7 productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 966 92.83 207/223 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD1-26*01 F 3 8 10 14 8.10.14 [1.17.38.11] CTRDLSGSYSGAFDVW in-frame + atctggattcacctttggtgactttgctatgagctggtttcgccaggctccagggaaggggctggagtggctaggtttcattagaagcaaaatttatggtgggacaccagaatacgccgcgtctgtgaaaggcagatgtcccatctcaagagatgattccaaaaacatcgcctatctgcaaataaacggcctgaaaaccgaggacacagccatgtatttctgtaccagagatctcagtgggagctactccggtgcttttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19178 JY8QFUQ01BZXH0 No results +19179 JY8QFUQ01AQDMW No results +19180 JY8QFUQ01AM1OS productive (see comment) Homsap IGHV4-61*02 F 929 91.4 202/221 nt 90.95 201/221 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARAWNGDYEVGWFDPW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); tctctggtgactccatcggtaatggaagttactactggagctgggtccggcagtccgccgagaagggactggagtggattggacatatctataccagAggggagcaccaactacaacccctccctcaagagtcgagtcaccatttcagccgacacgtccaagaatcagatctccctgaagttgacctctgtgaccgccgcagacacggccgtatattactgtgcgagggcgtggaacggtgactacgaggtgggctggttcgacccctggggccaggggaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +19181 JY8QFUQ01C6P3H unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDV# out-of-frame + stop codons ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctgggccaagggacaatagtcaccgtctcctcaggcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagcacctcctgggggcacagcggccctgggctggcctggtcaaggactacttccccgaaccggtgacggtgtctggaactca +19182 JY8QFUQ01BKVTV productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 657 78.34 170/217 nt 77.88 169/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [2.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (78,34% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); gtctctggggttcaccatcagtcactactccatggcctGgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccttgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +19183 JY8QFUQ01ABTVQ productive Homsap IGHV1-18*01 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD2-21*02 F 3 8 8 17 8.8.17 [0.17.38.11] CVREESIVVVTGRRGMDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggcctggagtggatgggatgggtcagcggttataatgataaatccaactatgcacagaagttcaaagacagaattatcatgaccacagacatatcaacgagcacagcctacatggagctgaggagcctgagatctgacgacacggccatgtattattgtgttagagaagagtcaattgtggtggtgaccgggcggcggggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19184 JY8QFUQ01AXLNQ productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag +19185 JY8QFUQ01CSTAE unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1013 96.33 210/218 nt 95.87 209/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-3*01 F 1 8 8 X 8.8.X [1.17.38.11] CTRPGVGGLFF##DFW out-of-frame - stop codons in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); gttctggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgggtggcgatcaCtctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtacgagaccaggagtggggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19186 JY8QFUQ01CC95Y productive (see comment) Homsap IGHV3-7*01 F 945 93.09 202/217 nt 91.71 199/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CATSPSDFDRRWGYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 28 of V-REGION: 'TT' (2 nucleotides at position 9 to 10 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 71 of V-REGION: 'C' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); ctctggatTTtagcttttagaaccttttggatgagctgggtccgccaggctccagggagggggctggagtgggtggccaacatAaaagtcagatggaagtgacaaatggtatgtggactctgCtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19187 JY8QFUQ01AY0OW No results +19188 JY8QFUQ01BW1WP productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1026 97.24 211/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD1-26*01 F 3 8 8 18 8.8.18 [1.17.38.11] CAKELGRALTGNYYQYFHYW in-frame + ctctggattcacgttcagtggctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtatcatatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctctctctgcaaatgaacagcctgagagctgaggacacggctgtatattactgtgcgaaagaattggggagggccctgactgggaactactaccagtactttcactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +19189 JY8QFUQ01CBEK7 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacatactggatgcactgggtccgccCaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19190 JY8QFUQ01A0DCS productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame - gttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19191 JY8QFUQ01CHVJM productive Homsap IGHV4-61*02 F 893 89.59 198/221 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARDPRVICSGGSCRSSAMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaacccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagaccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +19192 JY8QFUQ01CWNDC No results +19193 JY8QFUQ01BF9XY No results +19194 JY8QFUQ01BHNKP No results +19195 JY8QFUQ01CB41Y productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P 809 86.51 186/215 nt 85.12 183/215 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARGFSAWGQDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'TTT' (3 nucleotides at position 99 to 101 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); tctctggatttatcttcagtgattatagcatgaattgGggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtacTTTcgaatattacgcggGactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19196 JY8QFUQ01C3JVZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19197 JY8QFUQ01BD3GL productive (see comment) Homsap IGHV3-48*02 F (see comment) 672 78.18 172/220 nt 77.73 171/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [2.17.38.11] CARSTDGYYDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (78,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gctctgggattcccccttcaatatatggagcatgaattgggtccgccaggctccggGggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcgccctgctcccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19198 JY8QFUQ01CPYHI productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19199 JY8QFUQ01BUTOJ productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19200 JY8QFUQ01CNYY7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcanttccccgaaccggtgacggtgtgcgtggaactca +19201 JY8QFUQ01BMXAH unknown (see comment) Homsap IGHV3-74*03 F 851 88.07 192/218 nt Homsap IGHJ2*01 F (see comment) 36 66.67 12/18 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgccca +19202 JY8QFUQ01DOX9C productive Homsap IGHV3-30*01 F 981 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 9 8.8.9 [1.17.38.11] CARDNSGYNCW in-frame - ctctggattcaccttcagtcactatgctatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcatctgatgaaagtgataaatattatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacaacctgacagatgaggacacggctgtgtattactgcgcgagagacaatagtggttataactgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19203 JY8QFUQ01BOGEI No results +19204 JY8QFUQ01AITVH productive Homsap IGHV3-11*01 F 846 88.02 191/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD1-26*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARDGDDYRSYYYGMDVW in-frame - ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcatggtatacctggcagactctgtgaagggccgattcatcatctccagggacaacggcgagaactcactgtatcttcaaatgaacagcctgagagccgaagacacggccgtgtattactgtgcgagagatggggacgactacaggtcgtactactatggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19205 JY8QFUQ01CH0MW productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 921 90.58 202/223 nt Homsap IGHJ4*02 F (see comment) 231 97.92 47/48 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [2.17.38.11] CARDRLGSCSGASCPVYYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tgtctctggtggctccatcaacagtggtgattcctcctggacctggatccgccagtacccagggaagggcctggagtggattgggtacatctctggcagtggggactcctactccaacccggccctcaagagtcgagttaccatatcagtggacacgtctaagagccagttcttcctggaactgagttctgtgactgccgcggacacggccgtctattactgtgcgagagatcggctgggatcttgtagtggggctagctgccccgtctactactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19206 JY8QFUQ01BQDHE productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + cctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaactcag +19207 JY8QFUQ01CQJQW unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 877 89.81 194/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - tccggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19208 JY8QFUQ01CQ0GJ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 917 92.09 198/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 33 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgactgggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +19209 JY8QFUQ01B2QLD No results +19210 JY8QFUQ01CJ25K No results +19211 JY8QFUQ01CJWDI productive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARCPNYNIGTRGFDYW in-frame + tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19212 JY8QFUQ01AO8O3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19213 JY8QFUQ01DXHPU No results +19214 JY8QFUQ01DHZXV No results +19215 JY8QFUQ01B0W2M productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +19216 JY8QFUQ01BXDPP productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 851 88.07 192/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-2*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDRTLHTPAQMSYYGMDVW in-frame - catctggattcaccttcagttcttatagtgtaaactgggtccgccaggctccagggaagggcctagagtttgtctcatacattgatagtagtggttctaccatatactacgcagactctgtgaagggccgattcaccatctctagagacaatgcccagaactcactgtttctgcaaatgaacaacctgcgagtcgacgacacggccgtatattactgtgcaaaagaccggacacttcacacacccgctcagatgtcttactatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatctccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19217 JY8QFUQ01ANM6A No results +19218 JY8QFUQ01B4H18 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19219 JY8QFUQ01B7KDD productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 732 82.71 177/214 nt 82.24 176/214 nt Homsap IGHJ6*02 F 179 77.05 47/61 nt Homsap IGHD2-15*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDKVISAGRDVW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01B7KDD ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (82,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcagtttcactggttttaccgtgatctgggtccgccaggctccaaggaaggGggctggaatggatctcatccgtcactactaatggtctcacgtactacgcagactcagtagaaggccgattcaacatctccagggacaacgccaacaatttagtgtttctgcaaatgaacagcctgagagtcgaggacactggtgtatattattgtgcgagagataaagtgatctctgccggacgggacgtctggggccaagggaccacggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19220 JY8QFUQ01ARNJT No results +19221 JY8QFUQ01COA0U productive Homsap IGHV2-5*02 F 1116 95.49 233/244 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 10 7 14 10.7.14 [9.17.38.11] CAHIRAELSTSCHAFW in-frame + gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccaggaaaggccctggagtggcttgcacttgtttattgggatgatgataagcgctacagctcatctctgaagagcagactcaccatcaccaaggacacctccaaaaaccaggtggtccttacaatgactaacatggaccctatggacacagccacatattactgtgcacacattagggcggaacttagtaccagctgccatgccttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +19222 JY8QFUQ01B702Z unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 639 76.96 167/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (76,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19223 JY8QFUQ01AKNSQ productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CATISDYRFEFW in-frame + ctctggattcacctttagtggctattggatgagttgggtccgccaggctccggggaagggtctggagtgggtggccaacatagagaaagatggaagtgacataaagtatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtctctgcaaatgaacagcctgagagccgacgacacggctatttattactgtgcgaccattagtgactaccgatttgaattctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +19224 JY8QFUQ01B2QMW productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +19225 JY8QFUQ01CB4PE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19226 JY8QFUQ01A6CYA unproductive (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F (see comment) 409 80.16 101/126 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 X 4 X X.4.X [X.X.38.11] CASFAGPVVVTL*WLLVRLT#YCDYR out-of-frame + stop codons Low V-REGION identity (80,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctgcattcaccgtcagtaggctccgtgacgggccgagtcatcatctccagagagaatgcccagaactccgtgtatcttccactgaacagcctgagagccgggaacacggctgtgtatcactgcgcaagttttgctggccctgtggtggtgactctatagtggctgttggtccgtctgaccactactgtgactaccggggcctgggaaccccggtccccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +19227 JY8QFUQ01CGCX3 productive (see comment) Homsap IGHV4-61*02 F 1004 95.87 209/218 nt 94.5 206/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 2 9 7 17 9.7.17 [1.17.38.11] CARAPESSVYYLRGGFDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'CTT' (3 nucleotides at position 28 to 30 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 3 nucleotides (from position 27 in the user submitted sequence), (do not cause frameshift) tctctggtgactccatcaacagtggtaCTTactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggaccaccaactacaaccCcctccctcaagagtcgagtcaccatatcagtggacacgtccaagaaccagttctccctcaagctgacctctgtgagcgccgcagacacggccgtgtactactgtgcgagagcgcctgagagtagtgtttattacctcaggggcggctttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagataggaacgtggtcgtcgcatgcctggtccagggcttcttccc +19228 JY8QFUQ01DDMDO No results +19229 JY8QFUQ01BJVZ3 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 871 88.29 196/222 nt 87.84 195/222 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [3.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); aggcctcctggattcaCcctttggttattatggcatggactgggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19230 JY8QFUQ01DGH6B unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 489 82.98 117/141 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (82,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag +19231 JY8QFUQ01CYS7P productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +19232 JY8QFUQ01CZ6B1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19233 JY8QFUQ01A6IZH productive (see comment) Homsap IGHV3-7*01 F 891 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgagGaaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19234 JY8QFUQ01AJFJ5 unknown (see comment) Homsap IGHV3-23*05 F 91 51.82 71/137 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found stop codons cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccga +19235 JY8QFUQ01BTJDV productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgagacag +19236 JY8QFUQ01CRUAF productive (see comment) Homsap IGHV1-69*06 F, or Homsap IGHV1-69*14 F 844 88.73 189/213 nt 88.26 188/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-7*01 F 1 8 8 9 8.8.9 [0.16.38.11] CVIKTSYYDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 73 in the user submitted sequence), (cause frameshift) tggaggcaccttcaacaccattacttttagttgggtgcgacaggcccctggacaagggctcgagtggatgggggggtcatccctctctttagtagaacaaattacgcagaaaacttccagggcagagtcacaattaccgcggacaagtccacgaccacagcctacatggagttgagcagcctgagatttgaggacacggccatgtattactgtgtgatcaaaactagttattatgactactggggcctgggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19237 JY8QFUQ01ATVO9 No results +19238 JY8QFUQ01BGBEV productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [2.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'GA' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift); agtctctggattcaccgtcaatagGAaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacgcggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19239 JY8QFUQ01B8YFN productive (see comment) Homsap IGHV3-7*01 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARVNKDSTDMW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtgactattggatgaggtggttccgccagcctccaggaaGgggggctggagtgggtggccagcataaaagaagatggaagtgagaaaggttatgtggactctgtgaagggccgcttcaccatcgccagagacaacgcccagaaatcactgtttttgcagatgaacagcctgagaggcgaggacacggctgtgtatttctgtgcgagagtcaacaaggactctactgatatgtggggccaagggacaatggtcaccgtctcttcagcatccccggaccagccccgaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtccatcgcctgccctggtccagggcttcttcccccc +19240 JY8QFUQ01A2CO4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGPHQYYFDYW in-frame + cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19241 JY8QFUQ01B0UBH No results +19242 JY8QFUQ01AFB9Q productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD1-26*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARDREGARGYGMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtagctatagcatgaactgggtccgccagactccagggaaggggctggagtgggtctcatcccttagtagtggtagtatttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagtcactatatctgcaaatgaacagcctgagagccgaagacacggctatatattattgtgcgagagatcgggagggagctagaggttacggtatggacgtctggggccaagggaccacggtcaccgtctcgtcagcatccccgacagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19243 JY8QFUQ01A9EPX productive (see comment) Homsap IGHV3-7*01 F 835 87.44 188/215 nt 86.05 185/215 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 7 8 12 7.8.12 [1.16.38.11] CVRDRPGGWALDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift) ctctggattcagttttagtgacttttgatgcactgggtccgccaggcnccagggaaTggggctggagtggtggcccacntgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +19244 JY8QFUQ01CBP0J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD4-11*01 ORF 3 8 8 15 8.8.15 [1.17.38.11] CAKCDGVTVTKCYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagttttgccatgagttgggtccgccagcctccagggaaggggctggagtggatctcaactgtgactggtagtggaacttccacatactacgcagactccgtgaagggccacttctccatctccagagacaattccaagaaaacgctgaatctgcacatgaacagcctgacggtcggagacactggcttatattactgtgcgaaatgcgatggggtgacagtgactaagtgctactttgactcctggggccagggaaccctggtcaccgtctccccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19245 JY8QFUQ01C3JWV unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*05 F 161 54.49 97/178 nt 8 7 X 8.7.X [1.17.25.X] null + No rearrangement found cctctgcattcaccttcagtagctacgacatgcactgggtccgccaagcaacaggaagaggtctggagtgggtctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19246 JY8QFUQ01DC4HY unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [1.17.38.11] CARGSYWHYDTLR#DYW out-of-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttgcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +19247 JY8QFUQ01BUREX productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 7 10 9.7.10 [1.17.38.11] CASHGGKYFPQW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcCccccagggaaggggctggagtggattggacaaatccatcatggtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc +19248 JY8QFUQ01BWJ7A productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gcctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaAaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattattgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacatggtcatcgcctgcctggtccagggcttcttccccca +19249 JY8QFUQ01BCUIZ unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 724 85.35 169/198 nt 84.34 167/198 nt 8 2 X 8.2.X [2.17.37.X] null - No rearrangement found stop codons in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 88 in the user submitted sequence), (do not cause frameshift) gtctgtggtgggtccttcagtggtttctacCtagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19250 JY8QFUQ01DCHNV productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame - ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19251 JY8QFUQ01A4IA0 unproductive Homsap IGHV2-5*02 F 1134 96.31 235/244 nt 95.9 234/244 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 10 7 X 10.7.X [9.17.38.11] CAHRSFYGDYVFD#PG out-of-frame + in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaacttctctgggttctcactcaccactaGggggaatgggtgtgggatggatccgccagcccccaggaaaggccctggagtggcttgcactcatttattgggatgatgataagcgatacaggccatctctgacgagcaggctcaccatcaccaaggacacctccaaaaaccaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacagatcgttctacggcgactacgtcttcgaccccctggggcccgggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcatcgcctgcctggtccagggcttcttccc +19252 JY8QFUQ01C6P1B productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + ctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19253 JY8QFUQ01CIXG9 productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19254 JY8QFUQ01BLM96 unknown (see comment) Homsap IGHV3-7*03 F 968 94.04 205/218 nt 93.58 204/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagCtccccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccaggggaacccctggtcaacgtctcatcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctcccc +19255 JY8QFUQ01BJ9AX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 2 8 8 9 8.8.9 [1.17.38.11] CARDNYGDYWG in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19256 JY8QFUQ01CLG1V productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKRRGGYYIDFDYW in-frame + cctctggattcacctttactagttacagtttcaattgggtccgccaggctccagggaaggggctggagtgggtctcaactatcaatactagtggtagtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacgaggtgtatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaagcggaggggtggttattacatcgactttgactactggggccagggaacgctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19257 JY8QFUQ01APUSH productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19258 JY8QFUQ01CDEJB No results +19259 JY8QFUQ01CS32Q productive (see comment) Homsap IGHV3-9*01 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggattcacctttcatgattataccatgcactGgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctgcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +19260 JY8QFUQ01CDPLW No results +19261 JY8QFUQ01BH5JB productive Homsap IGHV4-61*03 F (see comment) 782 85.12 183/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD4-17*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARNDHGMWDAFHLW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (8 AA in JY8QFUQ01BH5JB ; 10 AA in Homsap_IGHV4-61*03) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgactctatggcaagctattactggagttggctccggcagcccccaggggagagactggaatggattgggtacatatattccactgggagcaccaactacaacccctcctttaagagtcgagtcaccatttcaatagacaccccgaagaaccacctctccctgaaattgaaatctgtgaccgctgcagacacggccgtgtatttttgtgcgaggaacgaccacggtatgtgggatgcatttcatctctggggccaagggacactggtcaccgtcacctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19262 JY8QFUQ01BH0Y7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 783 84.79 184/217 nt 84.33 183/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [1.17.38.11] CTKTRVVLGITFPFYIYGLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); ctctggattcacgttcgacaactatgccatgagctgggtccgccaggcaccaggaaaggggctggagtgggtctccagtattagtggtaatggagaaattgtacaccacgcagacgccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgTtttttgcaaatgaatggagtgagagacgacgacacggccatttactactgtacgaaaacacgcgttgtgttgggaattacatttccgttctatatctatggtctggacgtctggggccaagggaccacggtcaacgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19263 JY8QFUQ01CROIY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ3*02 F (see comment) 124 72.0 36/50 nt Homsap IGHD2-8*02 F 2 8 8 20 8.8.20 [1.17.38.11] CARDLWLCSGGECYHRGGFENW in-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctgggttcaccttcagtaactcctggatgcactgggtccgccaagctccagggaaggggccggagtgggtctcacgtattaatagtgatgggagtaatacaatctacgcggactccgtgaagggccgactcaccatctccagagacaacgccaaaaacacggtgtatctgcaattgaacagtctgagagccgaggacacggctgtgtactactgtgcaagagatctgtggctttgtagtggtggtgaatgctatcatcggggtggttttgagaactggggccgcggcgcactagtcacagtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +19264 JY8QFUQ01ANE0F No results +19265 JY8QFUQ01CQ8WJ unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 122 55.12 70/127 nt 8 8 X 8.8.X [1.17.8.X] null + No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc +19266 JY8QFUQ01ABJNQ productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame - ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19267 JY8QFUQ01CBUUD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD3-9*01 F 2 8 8 18 8.8.18 [1.17.38.11] CVKVAGDYRTPNYGWHFDLW in-frame + ctctggattcacctttagcacctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggtagtggtggcagcacattctactcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactggatctgcaaatgaatagcctgagaggcgaagacacggccgcatattactgtgtgaaagtggccggtgactatagaactcccaactacggctggcacttcgatctctggggccgaggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19268 JY8QFUQ01AUA3S No results +19269 JY8QFUQ01CJLGS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatGgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19270 JY8QFUQ01A2FLM unproductive Homsap IGHV3-30*01 F 869 88.99 194/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDSVPRASEAAYHFDY## out-of-frame + cctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattgggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19271 JY8QFUQ01B4XWG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19272 JY8QFUQ01A2EKG productive (see comment) Homsap IGHV3-9*01 F 877 89.81 194/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'G' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift); tctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgGggtctccggtatcactgggaatagtggttccataggcGtatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19273 JY8QFUQ01CGA3R No results +19274 JY8QFUQ01B0VB9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 823 87.04 188/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + tctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatcttcagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19275 JY8QFUQ01CA6ON productive Homsap IGHV3-74*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +19276 JY8QFUQ01B2Y4F unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 650 85.71 150/175 nt 8 8 X 8.8.X [2.17.23.X] null + No rearrangement found gcctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgc +19277 JY8QFUQ01CWOSR productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame - ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19278 JY8QFUQ01ALTMD unproductive Homsap IGHV3-48*03 F 824 86.7 189/218 nt 86.24 188/218 nt Homsap IGHJ5*01 F (see comment) 111 68.63 35/51 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDKGWSGYGMDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); ctctgggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggGggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccccaaggtcttccccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag +19279 JY8QFUQ01B9180 No results +19280 JY8QFUQ01BWUNA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19281 JY8QFUQ01CXBZN unproductive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-8*02 F 1 8 8 X 8.8.X [0.17.38.11] CARDGYLPGNG#DFW out-of-frame + tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacgggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +19282 JY8QFUQ01CA9GA productive (see comment) Homsap IGHV4-55*03 P (see comment) 734 82.03 178/217 nt 81.57 177/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 9 7 15 9.7.15 [1.17.38.11] CARDQSVYTAGSYFDSW in-frame + Potentially, because of detected insertion/deletion however the closest V is a pseudogene Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); tctctggtgactccatgagtagcgacacgtggtggagctgggtccgccagacgccagagaagggactggaatggattggggagatcaatcaaagagggacgacctcctacaacccgtccctcaggagtcgagtcgtcctgtcagtgggcgagtccaaaaaGtcaattctccctgaggctgacctctgtgaccgccgcggactcggccatctattattgtgcgagagatcagtctgtctatactgcgggaagttactttgactcctggggccagggaacgctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19283 JY8QFUQ01AS6RF unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgcctgagcctcgacagcaccccccgaagatggaacgtcggtcgtcgcatgcctggtccagggcttcttccccca +19284 JY8QFUQ01DOAEK unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggtaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctcggtccagggcttcttcccccga +19285 JY8QFUQ01BJ238 productive (see comment) Homsap IGHV4-61*02 F 870 88.24 195/221 nt 87.78 194/221 nt Homsap IGHJ5*02 F 101 64.71 33/51 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [2.17.37.11] CARDFGGSYNLVATG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) gtctctggtgactccatcagtagtgattctcattactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttntgtgcgagagattttggaggttcctacaatttagtggctactgggggcaggggaaccctggtcaccnnctccctcaggcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19286 JY8QFUQ01BBNSY No results +19287 JY8QFUQ01B9LZA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19288 JY8QFUQ01DK3MS productive Homsap IGHV1-24*01 F 988 96.24 205/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame - ggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt +19289 JY8QFUQ01CL5LY productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag +19290 JY8QFUQ01AFS5H unproductive (see comment) Homsap IGHV3-9*01 F 810 86.18 187/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CVKDRKSWWLQSV#DAFDIW out-of-frame - stop codons ctctggattcaccttcgacgactatgtcatgcattgggtccggcaagttccagagaggggcctggagtgggtcgcaggcattaatggggaaagtaatagttttggctctgtggactctgtaaagggccgattcaccatctccagagacaaggccaagaataccctgtatttgcaaatgaatagcctgagagttgaggacacggccttgtattattgtgtgaaagatagaaaaagctggtggctacaatctgttggatgcttttgatatctggggccaagggacaatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +19291 JY8QFUQ01B7C5Q unknown (see comment) Homsap IGHV3-16*01 ORF, or Homsap IGHV3-16*02 ORF or Homsap IGHV3-19*01 P or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-35*01 ORF or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 139 88.57 31/35 nt 8 X X 8.X.X [1.2.X.X] null - No rearrangement found cctctggattcaccttcagcaaccataacatgaac +19292 JY8QFUQ01AI4LK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19293 JY8QFUQ01AXYU7 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1031 97.25 212/218 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGPHQYYFDY## out-of-frame + cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggttggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactactttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19294 JY8QFUQ01APQJP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 878 89.45 195/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); tctccggattcacctttactaattattggGatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacAaaactacgcggactccgtggGaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +19295 JY8QFUQ01BNYRB No results +19296 JY8QFUQ01AHTJQ No results +19297 JY8QFUQ01A58QT productive (see comment) Homsap IGHV3-7*01 F 1004 95.87 209/218 nt 95.41 208/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); gctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggGggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19298 JY8QFUQ01BBL4C productive (see comment) Homsap IGHV3-11*01 F 980 95.35 205/215 nt 94.88 204/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD1-1*01 F 3 8 8 13 8.8.13 [1.17.37.11] CARVNTWNADYFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 3 nucleotides (from position 105 in the user submitted sequence), (do not cause frameshift) cctctggattcaccttcagtgactactacatgatctggatccgccaggctccagggaaggggctggagtgggtttcatacattactagtcgtggtactatcatgtacgcagactctgtgaagggccgattcaccatctccagggataacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggccatttattactgtgcgagagtgaacacatggaacgccgactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +19299 JY8QFUQ01B0KHU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactc +19300 JY8QFUQ01BE293 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +19301 JY8QFUQ01AETK0 productive (see comment) Homsap IGHV3-7*01 F 918 91.28 199/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift); cctctggatttacttttaacaacnattggatgacctgggttcgccagGgctccagggGAaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatccgctcttacccccgtggcgccctgctcccaggagccacctccgagaggcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19302 JY8QFUQ01CJV6U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [0.17.38.11] CVKDISRSGCFEYW in-frame - ctggattccagtttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19303 JY8QFUQ01DUQO7 No results +19304 JY8QFUQ01ASNDA No results +19305 JY8QFUQ01CLS2T unknown (see comment) Homsap IGHV3-23*05 F 135 55.56 75/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons cctctgggttcacctttagcagctatgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19306 JY8QFUQ01AR158 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 915 90.91 200/220 nt 90.45 199/220 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CVRGGSQWGPSGGGFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgataGgttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgacgacacggctgtttactactgtgtgagaggggggagtcagtgggggccttcaggtggggggtttgactactgggggccagggaaccctggccaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgcccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcaggc +19307 JY8QFUQ01AMNX3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - cctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19308 JY8QFUQ01ACE1O productive Homsap IGHV4-39*07 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-10*01 F 2 9 7 16 9.7.16 [1.17.38.11] CARAVLDNAWPIYYDFWG in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (9 AA in JY8QFUQ01ACE1O ; 10 AA in Homsap_IGHV4-39*07), and low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctggtggctccatcaccacttggcattactggggctggatccgccagcccccaggggagggtctggaatggattggaaatgtctatcataatggcaatatcgcctatagcccgtcgcagaggagtcgaatcaccatatcagtagacacgtccaggaaccagttctccctgaagatgacctctgtgaccgccgcggacacggctgtctattactgtgcgagggctgttcttgacaatgcctggcctatatattatgacttttgggggcccaggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19309 JY8QFUQ01AHDG8 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 595 82.66 143/173 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found Low V-REGION identity (82,66% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaggggctggagtgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgc +19310 JY8QFUQ01BZKHD productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1085 100.0 218/218 nt 99.08 216/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [2.16.38.11] CARDFFIGGYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggaTttcaccttcagtagctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19311 JY8QFUQ01BCZUP productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19312 JY8QFUQ01DWIRJ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 163 92.11 35/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found cctctggattcaccttcaggagttatatcatgaactgg +19313 JY8QFUQ01CUUUD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19314 JY8QFUQ01C6FIQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19315 JY8QFUQ01C9HBL productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19316 JY8QFUQ01BLKNY productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 957 94.39 202/214 nt 93.46 200/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 15 8.8.15 [0.17.38.11] CAKEQEPHGHYVGTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); tggattcGaccttcagtaGgctacggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggccgtgtattcctgtgcgaaagaacaagaaccacatgggcattatgttggaactgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19317 JY8QFUQ01B1UYR productive Homsap IGHV3-21*04 F (see comment) 662 78.44 171/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVRLFTSDGVRGDYW in-frame + Low V-REGION identity (78,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctccggtttcatcttcagtcacttcagcatgaactgggtccgccaggctccaggaaagggcctggagtggatcgccgacatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcgacgatacggccacctattattgtgtgaggctcttcaccagcgatggagtgagaggcgactactggggccagggcgcccgggttctcgtctccgcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19318 JY8QFUQ01A8C2S productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgtgtctgtggaactcag +19319 JY8QFUQ01AOJC3 unproductive Homsap IGHV3-7*01 F 969 93.64 206/220 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [2.17.38.11] CARVGYGYRGIYFFDY## out-of-frame + agcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccaatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +19320 JY8QFUQ01BEH1V productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt 84.4 184/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); gtctcggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19321 JY8QFUQ01BGBZ4 unproductive Homsap IGHV3-11*01 F 846 88.02 191/217 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CADINWV#WCFDLW out-of-frame + ctctgaaatcaccttcagcgaccactacatgagctggatccgccaggctccaggaaaggggctggaatggatttcatatattagcaccagtggtaatatgatctattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaggtcgatgtatttgcagatgaacagtctgagagccgaggacacggccgtctatttctgtgccgatataaactgggtgactggtgcttcgatctctggggccgtggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19322 JY8QFUQ01B71JV productive Homsap IGHV3-48*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGNYYYFGMDVW in-frame + ctctggattcctcttcagtagctttaacatgaactgggtccgccaggttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccatctactactgtgcgagacaaactgggaattattattacttcggtatggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19323 JY8QFUQ01AJSTD unproductive (see comment) Homsap IGHV3-21*04 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRAGVRELIG#FDCW out-of-frame + stop codons cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtcgcatccattagtagtagtagtggttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctggcagccgaggacacggccttatatcactgtgtgagagcaggggttcgggagttgatcgggctttgactgctggggccagggaaccctggtcaccgtgtccctcaggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19324 JY8QFUQ01CFHQE unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.89 192/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19325 JY8QFUQ01A3XIT productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 973 94.06 206/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'CG' (2 nucleotides at position 19 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcCGgggaactatagcatgaactgggtccgccacgctccagggaaggGggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19326 JY8QFUQ01A8802 No results +19327 JY8QFUQ01B1MND unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CVRGGLRWRPRTLLRP#YGLDVW out-of-frame - ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagagggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19328 JY8QFUQ01DGGA3 productive (see comment) Homsap IGHV3-9*01 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [2.17.38.11] CAKDIGVHMWTIDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); gcctctggattcacGatttgatgactatggcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggcattacttggaatagtggttacataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctacagatgaacagtctcagagctgacgacacggccttgtattactgtgcaaaagatattggggtacacatgtggaccattgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19329 JY8QFUQ01DDL8Y productive Homsap IGHV3-13*01 F 934 93.43 199/213 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-8*02 F 2 8 7 11 8.7.11 [1.17.38.11] CARWTAGCAFDIW in-frame + tctggattcaccttcagtacctacgacatgcactgggtccgccaagttacaggaaaaggtctggagtgggtctcagctatcggttttgctggtgacacttactattcaggctccgtgcagggccgattcgccatctccagagacaatgccaggaactccttgtatcttcaaatgagcagcctgagagccgaggacacggctgtctattactgtgcaaggtggacagctggttgtgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19330 JY8QFUQ01APLKP productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [2.17.38.11] CASGGYSGSGEYFLRW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); gcctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggGctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcatgcctggtccagggcttcttccccca +19331 JY8QFUQ01C8B7F productive (see comment) Homsap IGHV3-48*01 F (see comment) 774 84.33 183/217 nt 83.41 181/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [2.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) agcctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggGAaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +19332 JY8QFUQ01B2NHE productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 903 91.59 196/214 nt 91.12 195/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggGggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19333 JY8QFUQ01BK370 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 757 83.11 182/219 nt 82.19 180/219 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD3-16*02 F 3 7 7 X 7.7.X [2.17.38.11] CTGLTYPDDY## out-of-frame - Low V-REGION identity (83,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 31 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) acgtgctggactttaccttcagtaagttctgatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtataatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactgggggccagggatgtttggccaccgtctcctcagcatccccgaccagcccccaaggtcttccccgctgagccccctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +19334 JY8QFUQ01B6ICN productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19335 JY8QFUQ01CX9L2 productive (see comment) Homsap IGHV3-33*03 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); gtctggattGcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19336 JY8QFUQ01B1RZ8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGgggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19337 JY8QFUQ01BDK5R productive Homsap IGHV3-48*01 F 1080 99.54 216/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASIFGVVPLGNYYYGMDVW in-frame - ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19338 JY8QFUQ01AQTGO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19339 JY8QFUQ01AGEVS productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1030 95.56 215/225 nt 94.67 213/225 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*02 F 1 10 9 10 10.9.10 [1.17.38.11] CARDYRWAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 131 to 131 in the user submitted sequence), (cause frameshift); tccggggacaatgtctctagcaatactgtttcttggaactggatcaggcagtGccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggggtaatgattatgcagtatctgtgGaaaagtcgaataaccatcaacccagacacatccaagaaccaggtctccctgcagctgaactctgtgactcccgacgacacggctgtttattactgtgcaagagattaccggtgggcttttgatatctggggccaagggacattggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19340 JY8QFUQ01DAV05 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19341 JY8QFUQ01C0LID productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggAaaaggggccggtgtgggtctcacaaattCaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19342 JY8QFUQ01CWEZK unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 779 83.94 183/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19343 JY8QFUQ01COOTC productive (see comment) Homsap IGHV4-61*02 F 834 86.82 191/220 nt 86.36 190/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 9 7 15 9.7.15 [1.17.38.11] CARDTGQTYGRGPLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) tctctggtgcctccataataggggtaattattactggaactggatccggcagcccgccgggaagggcctggaatggattggccgaatctatacaagtgggagcaccatctacaacccctccctcgggggtcgagtcaccatgactgtagacccgtccgagaatcagttcttcctgagactgagttctgtgaccgccgcagacacggccgtttatttttgtgcgagagacactggacaaacctacggtcggggccctttggactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19344 JY8QFUQ01BZU7C productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19345 JY8QFUQ01ATJIB productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame - cctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19346 JY8QFUQ01CUAZE No results +19347 JY8QFUQ01AZD7R unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGCKQWL#DAFDFW out-of-frame + ctctggattcatctttagtagctatgccatgggctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgagcagcctgagagccgaagacacggccatatattactgtgcgaaaggttgcaagcagtggctgatgatgcttttgatttctggggccaagggacaatggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19348 JY8QFUQ01DB08D unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [2.17.38.11] CANASPPYNWN#YFYYYGMDVW out-of-frame + gcctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctcccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctggcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca +19349 JY8QFUQ01B58W5 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD3-3*01 F 2 8 8 21 8.8.21 [1.17.38.11] CVRVGAPYYDFWSGYQTNWFDPW in-frame + gtctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgctagtactacttccatacactatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggcgccatattacgatttctggagtggctatcagactaactggttcgacccctggggccagggaactctgtcaccgttacctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggcttcttcc +19350 JY8QFUQ01AJAPB productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19351 JY8QFUQ01AP7IU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19352 JY8QFUQ01AD1EE unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1000 95.43 209/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [2.17.38.11] CARDTLEVVSNMDDAFDVW# out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) gcctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaacgggctggagtggatctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctgggggcccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19353 JY8QFUQ01BJDA8 No results +19354 JY8QFUQ01ABO2E unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 953 93.95 202/215 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-2*01 F 3 8 7 X 8.7.X [1.17.38.11] CAVSTTTWG#WFDPW out-of-frame - tctatggtgggtccttcagtggttactactggagctggatccgccagcccccaggggaggggctgcagtggattggaagagtcaatcatagtggaagcaccagctacaacccgtccctcaagagtcgagtcaccatgtcactagacacgtccaagacccacttttccctgaagctgacctctgtgaccgccgcggacacggctgtgtattactgtgcggtgtctactaccacctggggggtggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19355 JY8QFUQ01AU9OQ unproductive (see comment) Homsap IGHV4-61*02 F 902 90.05 199/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 X 10.7.X [1.17.38.11] CAREK**SV#NWFDPW out-of-frame + stop codons tctctggtgactccatcaccagtggtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaatccctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagagaaaagtagtgatccgtcccaactggttcgacccctggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19356 JY8QFUQ01CMBQL productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1057 98.62 214/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARHAQYYYDSSGYYYLDYW in-frame - ttctggatacagctttaccagctactggatcggctgggtgcgccagatgcccgggaaaaggctggantggatggggatcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgagacacgcgcagtattactatgatagtagtggttattactacttagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19357 JY8QFUQ01BIVHX productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggccccatcggtcttccccccttggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaaactc +19358 JY8QFUQ01BUUP8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggGggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +19359 JY8QFUQ01CG36J unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1045 97.72 214/219 nt 96.35 211/219 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKSGVGAT#YFDYW out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'TA' (2 nucleotides at position 19 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'TG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); gcctctggattcacatttTAggcagctatgccatgAagctgggtccgccaggctccagggaaTGgggcttggagtgggtctcagctattagtggtagtggtggtggcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagtcaggggtgggagctacaactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19360 JY8QFUQ01A7LJV productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 674 79.53 171/215 nt 79.07 170/215 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,53% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 99 in the user submitted sequence), (do not cause frameshift) cctctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctaaagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtnttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca +19361 JY8QFUQ01B7U9F productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctcgggattcaccttcagtggctatagcatgaactgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccgaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactcag +19362 JY8QFUQ01CMLY6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - agcctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19363 JY8QFUQ01B9UPL productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19364 JY8QFUQ01DDX1E unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 393 87.25 89/102 nt 85.29 87/102 nt 8 8 X 8.8.X [1.15.1.X] null + No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 4 nucleotides (from position 49 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) ctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggaggggctgagtgggtctcagccattagtggcagtggtagtcggacatatt +19365 JY8QFUQ01CPQED No results +19366 JY8QFUQ01DC8OC productive (see comment) Homsap IGHV3-23*05 F 826 87.79 187/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgngcctcgacagcaccccccgaagactgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +19367 JY8QFUQ01CI4NV productive (see comment) Homsap IGHV4-39*03 F 902 90.0 198/220 nt 89.09 196/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'TT' (2 nucleotides at position 72 to 73 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaacagtagaAaattattattggggctggatccgccagccccccagggaagggttTTggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19368 JY8QFUQ01CPEF3 unknown (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F (see comment) 271 65.07 95/146 nt 8 8 X 8.8.X [1.17.14.X] null + No rearrangement found Low V-REGION identity (65,07% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19369 JY8QFUQ01B0F0W productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 968 94.04 205/218 nt Homsap IGHJ3*02 F 124 72.0 36/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDAFEMW in-frame + cctctggattcacctttgatgattttggcatgagttgggtccgccaagttccagggaaggggctggagtgggtcgctggtatcagttggaatggaggcaaaacaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcattggtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19370 JY8QFUQ01ARB7K unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 972 94.47 205/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDFTYAFDL## out-of-frame + gtctggattcacgttcagtagttatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatcatctggtatgatggaagtaatcaatattatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacggtgtatctacaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgaaagattttacgtacgcctttgatctctggggccaaggggacaatggtcaccgtctcttcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +19371 JY8QFUQ01CDDDZ productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +19372 JY8QFUQ01CPBGH productive (see comment) Homsap IGHV3-7*03 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARRVWGYKIGFPSYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggacCtctgtgaagggccgattcaccatctccagggacaacgccaggaactcagtgtatctgcaaatgaacagcctgggagccgacgacacggccgtgtattactgtgcgaggcgggtgtggggatacaaaattggattcccttcgtattactttgactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19373 JY8QFUQ01DUFLK productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 7 10 9.7.10 [1.17.38.11] CASHGGKYFPQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcccccagggaaggGggctggagtggattggacaaatccatcatgtggggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19374 JY8QFUQ01CCTL0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctctgggttcatctttagtagacattggatggcctgggtccgccaggctccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19375 JY8QFUQ01CB8J6 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CAREKGSGPPTGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggccaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +19376 JY8QFUQ01AM0T6 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 881 90.23 194/215 nt 89.3 192/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); tttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcgGgtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19377 JY8QFUQ01AJQEI productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19378 JY8QFUQ01BAJM3 No results +19379 JY8QFUQ01CN1RC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 744 82.27 181/220 nt 81.36 179/220 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [2.17.38.11] CARYRVGDSLYYGLDGW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'ACT' (3 nucleotides at position 93 to 95 in the user submitted sequence), (do not cause frameshift); agcctctggattcatttttagaaAattttgccatgagttggctccgccaggcaccagggaaggggctggaatgggtctcgactatcagcagcACTagtggtgacacggcatattactcagactccgtgaggggccgcttttccatctccagagacaactccaagagcactctgttcttgcagatgaacagcctgagtgccgaagacacggccatttactactgtgcgagataccgtgtgggtgacagtctctactacggtttggacggctggggccaagggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19380 JY8QFUQ01CP221 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - cctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19381 JY8QFUQ01DDTOX productive (see comment) Homsap IGHV4-61*01 F (see comment) 776 83.71 185/221 nt 82.35 182/221 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 175 to 175 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'C' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagTccccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccCctgaggctgaacgatgtgaccgctgcggacacggcCcatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtccaaggactacttccccgaaccggtgacggtgtcgtggaactc +19382 JY8QFUQ01A8FM1 productive (see comment) Homsap IGHV1-24*01 F 957 94.39 202/214 nt 93.93 201/214 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD3-16*01 F 2 8 8 11 8.8.11 [0.17.38.11] CVGDVGWGYPQGW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); cggatacaccctcaatgaattatccatgcactgggtgcgacagactcctggaaaagggcttgagtcgatgggcggAttttgatcctgaatatggtaaaacaatctacgcgcagaagttccagggcagagtcaccatgaccgaggacacatctgcagacacagcctacatggagttgagaagcctgagatttgaggacacggccgtgtattattgtgtcggagatgtcggctggggatacccccaaggctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19383 JY8QFUQ01AJU4U productive (see comment) Homsap IGHV3-7*01 F 1017 96.77 210/217 nt 96.31 209/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggGggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19384 JY8QFUQ01CZRZK unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 947 92.31 204/221 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [2.17.38.11] CARDQSLGDA#EAFDIW out-of-frame - stop codons cagcctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctgggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19385 JY8QFUQ01AP7PU productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'T' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccTttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19386 JY8QFUQ01BSZBN productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - tctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19387 JY8QFUQ01CGFHV productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 964 93.61 205/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gcctctggattcacctttggttattGatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +19388 JY8QFUQ01B6OUF unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGG# out-of-frame - cctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19389 JY8QFUQ01A0C4X productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19390 JY8QFUQ01AICLR unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.12 203/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19391 JY8QFUQ01B4XRW unknown (see comment) Homsap IGHV3-7*02 F 104 50.0 109/218 nt 49.54 108/218 nt Homsap IGHJ1*01 F (see comment) 17 71.43 5/7 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 49 of V-REGION: 'GG' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift); cctctggtttcacctttagtaacgattggatggactgggtccgccaggctccaggggaaGGgggctggagtgggtggccaatataaaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19392 JY8QFUQ01BFQS4 No results +19393 JY8QFUQ01B5DD0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19394 JY8QFUQ01ARWJL unknown (see comment) Homsap IGHV3-72*01 F 111 53.79 71/132 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +19395 JY8QFUQ01CQIMH productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 833 87.16 190/218 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARLRSFGDYPLDVW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19396 JY8QFUQ01BLY7Y unproductive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.17.38.11] CARGEMTAEYYFDYW in-frame - stop codons in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtgttCaactgatggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19397 JY8QFUQ01BFO9X productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19398 JY8QFUQ01AF7B4 unproductive Homsap IGHV4-39*07 F 787 85.19 184/216 nt 84.26 182/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 3 9 7 X 9.7.X [1.16.38.11] CARAVLDNAWPIYYDF## out-of-frame - in CDR1-IMGT, from codon 38 of V-REGION: 4 nucleotides (from position 34 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) tgtctggtggctccatcaccacttggcattactgggctggatccgccagcccccaggggagggtctggatggattggaaatgtctatcataatggcaatatcgcctatagcccgtcgcagaggagtcgaatcaccatatcagtagacacgtccaggaaccagttctccctgaagatgacctctgtgaccgccgcggacacggctgtctattactgtgcgagggctgttcttgacaatgcctggcctatatattatgacttttgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19399 JY8QFUQ01AEI8C productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19400 JY8QFUQ01AIEY8 productive (see comment) Homsap IGHV4-61*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 15 10.7.15 [1.17.37.11] CARNPSYSNSHQHCDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) tctctggtgcctccatcaacagtggtagttactactggagttgggttcggcagcccgccgagaagggactggagtggattgggcgtatctacaccagtgggagcaccaactacaaccctccctcaagagtcgagtcgccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctatttttgtgcgagaaatccctcttatagcaattcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19401 JY8QFUQ01BBAED unproductive (see comment) Homsap IGHV4-59*02 F (see comment) 755 83.72 180/215 nt 82.33 177/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 142 76.0 38/50 nt Homsap IGHD3-22*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARDGQ*EVITLLKPW in-frame + stop codons Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 36 of V-REGION: 'TGGAAAA' (7 nucleotides at position 23 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 176 to 176 in the user submitted sequence), (cause frameshift); tgtctggtggctccgtcagcagTGGAAAAttcctactggacttggatccgccagTccccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccCctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggccaatgagaggttattactcttttgaaaccctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19402 JY8QFUQ01CWZ29 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1066 99.54 215/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 1 8 7 9 8.7.9 [2.17.38.11] CARDTWPTSYW in-frame - gtctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacactgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagagatacctggccaacttcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19403 JY8QFUQ01B4A1V productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19404 JY8QFUQ01ACOK8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame + gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctctaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19405 JY8QFUQ01DL1RO No results +19406 JY8QFUQ01BCXFL No results +19407 JY8QFUQ01B54T1 unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1105 100.0 222/222 nt 99.55 221/222 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 8 10 X 8.10.X [1.17.37.11] CTKCSVTIYFFGLL# out-of-frame + stop codons in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 194 in the user submitted sequence), (cause frameshift) ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactca +19408 JY8QFUQ01ANIFJ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19409 JY8QFUQ01CU3J4 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt 94.12 208/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [2.16.38.11] CARHSRLVRYFEYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gtctctggtgactccatcagcagtagttcttactactgggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19410 JY8QFUQ01BOE49 unproductive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ5*01 F 111 68.63 35/51 nt 8 8 X 8.8.X [1.17.38.11] CARDQVTEDY (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactgggccaggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +19411 JY8QFUQ01BFAKE productive Homsap IGHV3-7*01 F 904 91.2 197/216 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + tctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19412 JY8QFUQ01A7GG5 No results +19413 JY8QFUQ01CVM2Y productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 973 94.06 206/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDRGCTNGACYVADFW in-frame - gcctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19414 JY8QFUQ01CB4HP No results +19415 JY8QFUQ01A33U2 productive (see comment) Homsap IGHV4-39*03 F 893 89.55 197/220 nt 88.64 195/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'TGG' (3 nucleotides at position 73 to 75 in the user submitted sequence), (do not cause frameshift); tctccggtggctccatcaacagtagaaAattattattggggctggatccgccagccccccagggaagggtttTGGgagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19416 JY8QFUQ01DM0IQ No results +19417 JY8QFUQ01CPVUP productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcatcgcatgcctggtccagggcttcttccccca +19418 JY8QFUQ01ATMY1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19419 JY8QFUQ01CJLF6 productive Homsap IGHV3-7*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + tctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19420 JY8QFUQ01C1AXI No results +19421 JY8QFUQ01BIXG5 productive Homsap IGHV3-11*01 F 954 93.55 203/217 nt Homsap IGHJ2*01 F (see comment) 211 88.68 47/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CADIRLGDWCFDIW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtgaccactacatgagttggatccgccaggctccagggaaggggctggagtggatttcatatattagtactagtggtaatatgatttattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaactcactgtatctgcagatgaacagcctgagagccgaggacacggccgtctatttctgtgccgatataagactgggtgactggtgcttcgatatctggggccggggcaccctggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19422 JY8QFUQ01AP8C2 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19423 JY8QFUQ01B1R7J No results +19424 JY8QFUQ01CJSEU productive Homsap IGHV3-7*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAREQSSRGYPLDYW in-frame + ctctggattcacctttgagacttattggttgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagacatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaggaactcactgtttctgcaaatgaacagcctgagaggcgacgacacggctgtctattactgtgcgagagaacaatcctcgaggggatacccacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19425 JY8QFUQ01DD2AN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 986 94.95 207/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19426 JY8QFUQ01BWQWD unproductive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDGSAIPVTGTYFEYW# out-of-frame + cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggcccaggggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19427 JY8QFUQ01B82FV unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggGggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19428 JY8QFUQ01B5T5L unproductive Homsap IGHV1-2*02 F 831 87.85 188/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [0.17.38.11] CARDGISMTLVRGVRPFDY## out-of-frame + tggatacaccttcatcggccattatatacattgggtgcgacaggcccctggacaagggcttgaatgggtggggtggatcaaccctaacagtggtgttacaaactatgcacagcagtttcaggacagggtcaccatgaccgtcgacacgtccatcagcactgcctacatggacctcaaaagtctaaagtctgacgacacggccatctattactgtgcgagagacggaataagtatgactctggttcggggagttaggcccttcgactactgggggccagggaaccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19429 JY8QFUQ01CDGFM No results +19430 JY8QFUQ01BO56U productive Homsap IGHV3-30*10 F (see comment) 734 82.11 179/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame - Low V-REGION identity (82,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19431 JY8QFUQ01CUNKR unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 434 77.03 114/148 nt 8 8 X 8.8.X [1.17.14.X] null - No rearrangement found Low V-REGION identity (77,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctacgtggtcgtcgcatgcctggtccagggcttcttccccca +19432 JY8QFUQ01DC9KF unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); gcctccggattcaccGtttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19433 JY8QFUQ01BU67O productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19434 JY8QFUQ01CFRCL productive (see comment) Homsap IGHV3-48*01 F 967 94.44 204/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 8 8 15 8.8.15 [1.16.38.11] CATVPRRGTGGYYLASW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagcCtatcccatgacctgggtccgccaggctcctgggaagggctggagtgggtttcatacattagtagtagtggtagaaccatttcctacgcggactctgtgaagggccgattcagcatctccagagacaatggcaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgcgacagttccccggcgggggaccggtggttattaccttgcctcttggggccagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19435 JY8QFUQ01ANXYC productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 926 92.56 199/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame - tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggctgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19436 JY8QFUQ01AZN62 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19437 JY8QFUQ01C4BQP No results +19438 JY8QFUQ01BG2JH No results +19439 JY8QFUQ01AOQG2 productive Homsap IGHV1-3*01 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDGESLGGDYFDYW in-frame + tggatacaccttcagtaattatgctatacattggttgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctggcacgggtaacacaaaatattcacagaagttccagggcagagtcaccattaccagggacacagccgcgaccacagcctacatggaattgagcagcctgaaatctgaggacacggccgtgtattactgtgcgagagatggggagtcactgggaggcgactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +19440 JY8QFUQ01DLCEW productive Homsap IGHV3-48*02 F 864 88.94 193/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD6-6*01 F 1 8 8 20 8.8.20 [1.17.38.11] CARDDSRLWSSSFNHYFAMDVW in-frame + ctctggattcacctttagtgattatagaatgaattgggtccgccaggctccagggatggggctggaatgggttgcacacattagtaccagtggtagtagtatatactatgcagactctgtgaagggccgattcaccgtctccagagacgatgccaagaattcactttttctgcaaatggacagcctgagagacgacgacacggctgtatattactgtgcgagagacgattcacggctgtggagctcgtcatttaaccactatttcgctatggacgtctggggccaagggaccaccgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagtgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19441 JY8QFUQ01AMS4U productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATDDSNGWDEVADYW in-frame + ctctggattcaccttcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcacgcacccagccagatgggaacgtgtcatcgcctgctggtccagggctctt +19442 JY8QFUQ01B2MMM productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'T' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatTgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +19443 JY8QFUQ01CKQ2N productive (see comment) Homsap IGHV3-7*01 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDGYYYYHSGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagagccgaggacacggttgtatattattgtgcgaaagacggctattattattatcacagcggtatggacgtctggggccaagggaccacggtcatcgtctcccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19444 JY8QFUQ01CCHD0 productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +19445 JY8QFUQ01BBUHG No results +19446 JY8QFUQ01BPM6Q unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +19447 JY8QFUQ01BPRI6 productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 962 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctatgcGtatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgnatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +19448 JY8QFUQ01CBYV8 No results +19449 JY8QFUQ01CESVQ No results +19450 JY8QFUQ01CB9GM unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [1.17.38.11] CAKKLTIGSQLLLQRFGRM# out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'CA' (2 nucleotides at position 62 to 63 in the user submitted sequence), (cause frameshift); tctctggtggcctcatcagtaattactattggacctggatccggcagcccccaggaaagggCAcatggagtggattgggaacatctattacagtgggagcgccacctacaacccctccctcaagagtcgagtcaccatatcaatagactcgtccaagaaccagttctccctgaggctgaccgctgtgaccgctgcggacacggccgtgtattactgtgcgaaaaaacttacgattgggtcacagttacttctacaacgctttggacgtatgggggccaagggaccacggtcaccgtcgcctcaacatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +19451 JY8QFUQ01B9PJJ unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 112 53.73 72/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19452 JY8QFUQ01BGUIW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacaacctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19453 JY8QFUQ01CDP6X No results +19454 JY8QFUQ01AFSCA unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARKRVPGGTFYGGLL# out-of-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatgggggactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19455 JY8QFUQ01A6QRO productive (see comment) Homsap IGHV3-7*01 F 964 93.61 205/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'A' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); gcctctacattcacgtttagtcggtattggatgagctgggtAccgccaggctccagggaagggcctggGagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19456 JY8QFUQ01BVQW1 No results +19457 JY8QFUQ01BZ4RA unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGAGAEGKGGMDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcaccttcaaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctgggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19458 JY8QFUQ01B5QDY productive Homsap IGHV3-7*01 F 887 89.91 196/218 nt Homsap IGHJ6*02 F (see comment) 103 62.9 39/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc +19459 JY8QFUQ01B4Z9U productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 931 92.59 200/216 nt 91.67 198/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.37.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 194 in the user submitted sequence), (cause frameshift) ttctggatacacatttatgaattattggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccaacaccgcctacgtgcagtggagcagcctgaaggcccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +19460 JY8QFUQ01A8DBN productive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19461 JY8QFUQ01AD3VH unproductive Homsap IGHV4-59*03 F (see comment) 728 82.33 177/215 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD3-9*01 F 2 8 7 X 8.7.X [1.17.38.11] CAREDPYFRHFDWIS##DPW out-of-frame + Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tttctggtggctccatcagaagttactattggagttgggtccggcagtccccagggacgggactggaatggattgggtacaagttctacagtgggcccgccaaatataatccctctctcgagggtcgagtcacaatttctatagacacgtcgaagagtcaattcttcctgaggatgacgtctgtcaccactgcggacacggccgtctattattgtgcgagagaggacccctatttccgacattttgactggatcagcaatcgacccctggggccagggaatcccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaact +19462 JY8QFUQ01CTC3W No results +19463 JY8QFUQ01DTXTG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19464 JY8QFUQ01AQEEF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19465 JY8QFUQ01BK5CM productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 850 90.34 187/207 nt 88.41 183/207 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 49 to 50 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 8 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) tctctggtgactccccacttctggagctggatccggcagccccccgggGAaagggcctggagtggattggttatgtctataacagtggGgaccaccaactacaaccCcctccctcaggagtcgagtcaccatgtctatagacacgtccaagaagcagatctctctgaggttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactcctggggccagggaaccctggtcaccgtctccggcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccag +19466 JY8QFUQ01A0XMS No results +19467 JY8QFUQ01BSZ2H No results +19468 JY8QFUQ01ABFGB productive (see comment) Homsap IGHV3-49*04 F 989 93.75 210/224 nt 92.41 207/224 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 10 17 8.10.17 [1.17.38.11] CTRDNPPLRSLEWLPFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 132 to 132 in the user submitted sequence), (cause frameshift); gctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcAaaagctgatgatgggacaacagaAatacgccgcgtctgtgaAaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19469 JY8QFUQ01A7C8P productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAIEHTLPSGQGLGIEYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); tctggattcaactttaacagctttgccatgagctgggtccgccaggttccagggaTgggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactccgtgaaggGgccggttcaccatctccagagacaactccaacaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgatcgagcatacccttccgtccggacagggattagggattgaatatttctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19470 JY8QFUQ01BBJ1V No results +19471 JY8QFUQ01AFBBD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagg +19472 JY8QFUQ01CIQUI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19473 JY8QFUQ01CMMBK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 615 92.96 132/142 nt 92.25 131/142 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 7 1 10 7.1.10 [1.X.38.11] CVSDLAGQKGFW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01CMMBK ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 38 of V-REGION: 75 nucleotides (from position 26 in the user submitted sequence), (do not cause frameshift) ctcaggattcaccttcagtagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19474 JY8QFUQ01A6IQL productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.17.38.11] CARGEMTAEYYFDYW in-frame + tctctggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19475 JY8QFUQ01AM9OB productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19476 JY8QFUQ01C1SED productive (see comment) Homsap IGHV3-9*01 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [2.17.38.11] CAKSGTYSSSSGHFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); gcctctggattcaactttaataaGttatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19477 JY8QFUQ01AR4F8 productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1038 96.41 215/223 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 10 17 8.10.17 [1.17.38.11] CTRDNPPLRSLEWLPFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ttctggattcacctttggtgattatagtatgagttggttccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcaaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19478 JY8QFUQ01BC1EW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F (see comment) 103 62.9 39/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKTVVPTAPNRFYYYYGLDVW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccaactgctcctaatcgattttactactactacggtttggacgtctggggcccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcgggtcttcccccctggcgccctgctccaggagcacctccgagancacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19479 JY8QFUQ01AWL52 productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDLTGYSSERNYW in-frame + gctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccggggggggctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19480 JY8QFUQ01B4BLC No results +19481 JY8QFUQ01CRAFM unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 908 91.63 197/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 79 62.0 31/50 nt Homsap IGHD2-21*01 F 3 8 7 X 8.7.X [1.17.38.11] CTRELRLAAARDGVDI## out-of-frame + cttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggtacaatggtcaccgtctcttcagcatcccctgaccagccccaaggtcttcccgctgagcctccgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19482 JY8QFUQ01CT4OG unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 398 66.34 134/202 nt 65.84 133/202 nt 8 8 X 8.8.X [2.16.32.X] null - No rearrangement found Low V-REGION identity (66,34% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) gcctctggattcccctttagcaactatgccatgacctgggtccgccaggctccagggagggactggaatgggtctcaagtattagaggtagtggtgacaggacatcctacgcagactccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19483 JY8QFUQ01BUAPX productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame - ctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattattgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19484 JY8QFUQ01AWY0L unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [2.17.38.11] CMNELGIL*WWG# out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 78 of V-REGION: 'A' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); gcctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatActccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcgggatattgtagtggtgggggggggccagggagccctggtctccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +19485 JY8QFUQ01C6ZTG productive Homsap IGHV3-7*03 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame - cctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19486 JY8QFUQ01AKO1A unproductive (see comment) Homsap IGHV3-33*03 F 887 89.91 196/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-10*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARRNCGSGSHCYYYCDMDVW in-frame + stop codons cgtctggattcactttcaggaactatgacatgcactgggtccgccaggctccaggcaaggggctggagtgggtgacaatcatgtgatatgatggaaataataaacactatgcaggctccgtgaagggccgattcaccatctccagagacacctccaaaaccacactgtatctgtaaatgaatagcctgagggccgaggacacggctctgtttcactgtgcgaggagaaactgtggctcggggagtcactgttattactactgcgatatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +19487 JY8QFUQ01CC9YT productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD3-3*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKQTIFDYYYYGLDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); cctctggattcatgtttagtagctttcccatggcctgggtccgccaggGctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19488 JY8QFUQ01B9JIY productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19489 JY8QFUQ01CHDDF productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 899 89.29 200/224 nt 87.95 197/224 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 2 8 10 12 8.10.12 [1.17.38.11] CTITVRPDDYHDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 169 to 169 in the user submitted sequence), (cause frameshift); tctctggagtcactttcactaacgtgtggatgagttgggtccggcaggctccagggaaggggccggagtggGgttggccgtattaaAaagggagactgagggggggacaatagactacgctgcacccgtgacagcaagattcaccatgtcaaaagatgattcaaaaaaTcacactatatctgcaaatgaacaacctgaaaatggaggacacagccgtgtattactgtaccataacagtccgaccggatgattaccatgactactggggccagggaaccctggtgaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggctccagg +19490 JY8QFUQ01BZDK8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 985 95.37 206/216 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19491 JY8QFUQ01CIMAM productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 899 91.16 196/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - tttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19492 JY8QFUQ01A4JKL unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 41 90.0 9/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctccggatt +19493 JY8QFUQ01CNDUC productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGLAVILGGFGPYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttggaccgtactggggccagggaaacctggtcaccgtctcctcagcctccagccaaggccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19494 JY8QFUQ01B2VXM No results +19495 JY8QFUQ01DGTCA productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARNELPWDTREYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift) cgtctggattcagtttcagtacctttggcatgagttggatccgccagacgccaggcaaggggctggagtgggtgacagttatatggtcggatggaactaaaaaaattatgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19496 JY8QFUQ01DJL4L unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P 126 54.81 74/135 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons cctctggattcatcttcagtgactactacatgacctggatccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19497 JY8QFUQ01A4HCT No results +19498 JY8QFUQ01C0HKY unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ3*02 F (see comment) 124 72.0 36/50 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKKYHYGSGSYLYCFDY## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtggtgatgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactgctttgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19499 JY8QFUQ01BGYLI unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF## out-of-frame - tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19500 JY8QFUQ01CKT96 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19501 JY8QFUQ01AGVK6 No results +19502 JY8QFUQ01DOO1T No results +19503 JY8QFUQ01BH2A1 productive Homsap IGHV1-2*02 F 921 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 1 8 8 12 8.8.12 [0.17.38.11] CATDVPAGQLWGYW in-frame - tggatacacattcaccgacaactatatgcactgggtgcggcaggcccctggacaggggcttgagtggatgggatggatcgaacctaacagtggagacacaaactatgcacaaaagtttcagggcagggtcaccatgacgagggacacgtccatcgccacagcctacatggagttgagcaggctgagagctgacgacacggccgtgtactactgtgcgaccgacgtccccgcagggcaactctggggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19504 JY8QFUQ01CJRYX unknown (see comment) Homsap IGHV3-7*01 F 932 92.2 201/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found cctctggatttacttttagcaactattggatgacctgggttcgccaggctccagggaaggggctggagtgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgcatctgcaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgagagggtcgtattatcattatgatatgtttggctgactactgggccagcgggaggtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19505 JY8QFUQ01C0KHV productive Homsap IGHV3-11*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame + cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcaccaaggtcttccccgctgagcctctgcagcacccagccagatgggaaacgtggtcaatcgcctgcctggtccaggggcttcttccccc +19506 JY8QFUQ01DPA6S productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1085 100.0 218/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDFFIGGYYGMDVW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +19507 JY8QFUQ01AELAP productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 920 90.95 201/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARASGRGDHGGDWFDPW in-frame + tctctggcgactccttcagtagtgctggttactattggagttggatccgccagcgcccagggaaaggcctggagtggattgggtccatctattacagtgggagtatctacttcaacccgtccctcaggagtcgaattaccatgtcagtggacacgtctaagaaccagttctccctgaagttgacctctgtgactgacgcggacacggccgtgtattactgtgcgagagcctctggtcgcggggatcacggtggggactggttcgacccctggagcctgggaaccctggtcaccgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttgctt +19508 JY8QFUQ01CEHX4 productive (see comment) Homsap IGHV4-39*02 F (see comment) 683 80.0 172/215 nt 79.53 171/215 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 9 7 19 9.7.19 [X.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); cctctggattcacctttggcagctatatcatgagctgggtccgccagcCccccagggaagggactggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc +19509 JY8QFUQ01ASEV1 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 745 83.57 178/213 nt 83.1 177/213 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.37.11] CARGTRYNNGLDAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 92 of V-REGION: 2 nucleotides (from position 178 in the user submitted sequence), (cause frameshift) tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19510 JY8QFUQ01BLO8E unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1091 99.55 220/221 nt 99.1 219/221 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD2-2*01 F 3 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSAN#YW out-of-frame + in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactGggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacagctgtgtattactgtgcgagaagtagaaccttctatggttcggccaacgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +19511 JY8QFUQ01AL0VQ No results +19512 JY8QFUQ01A3ULV unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 900 90.78 197/217 nt 89.4 194/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); atctggatacacctttatcacctactGggatcgcctgggtgcgccaaatgcccgggGAaaggccctggagttgatggggaGtcatctatcctggtgactctgagaccagatacagcccgtccttccaaggccacatcaccctctcagtcgacaagtccatcgataccgcctacctggagtggagcagcctgaaggcctcggacaccgccatgtacttctgtgcaagaagacaactggcccttgcctactgggggccagggaacccaggtcacccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19513 JY8QFUQ01ASLW8 productive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 966 94.86 203/214 nt 94.39 202/214 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 3 8 8 17 8.8.17 [0.17.38.11] CASLPGDLTQIQDGVFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggaggcaccttcgacagttatgttatcagctgggtgcgacaggGcccctggacaagggcttgagtggatgggcgggatcatccctatctttggttcggcaaagtatgcacagaagttccagggcagagtcaggattaccgcggacgaatccacgagcacggcctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgccagtcttcccggggatcttactcaaattcaagacggtgtttttgatatctggggccaggggacaatggtcagtgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcgcccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19514 JY8QFUQ01BRHNR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19515 JY8QFUQ01ACCN3 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt +19516 JY8QFUQ01B88R2 productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19517 JY8QFUQ01BKFUT unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 688 91.98 149/162 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-16*01 F 1 X 7 X X.7.X [X.9.38.11] CARHPRPGTFDYLGG#WFDPW out-of-frame - gggaaggggctggagtgccttgggagcatcttttatagtgggcgcaccaaccaggacccgtccctcaagagtcgagtcaccttatccgttgacacttccaagaaccagttctccctgaagctgagctctgtggccgccgcagacacggctgtgtattactgtgcgagacatccccgcccgggaacttttgactacttagggggggttggttcgacccctggggccagggaattccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19518 JY8QFUQ01BCY6I productive (see comment) Homsap IGHV3-23*05 F 814 86.57 187/216 nt 86.11 186/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [2.17.38.11] CAKRPPGTIDRW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 97 in the user submitted sequence), (do not cause frameshift) gcctctggatcaccctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19519 JY8QFUQ01AW5Y1 No results +19520 JY8QFUQ01AZS0F No results +19521 JY8QFUQ01ADD6P productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19522 JY8QFUQ01B3MKQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 1 8 8 18 8.8.18 [1.17.38.11] CAKDKNPVEMATISEILDYW in-frame - cctctggattcacctttaccaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgttgacacatactacgcagactccgtgaagggccggttcaccatctccagagacacttccaagaacacgctgtttctgcaaatgaccagcctgagagccgaggacacggccgtctattactgtgcgaaagataagaaccccgtagagatggctacaattagtgaaattctagactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19523 JY8QFUQ01BYGT0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'GG' (2 nucleotides at position 158 to 159 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccgagGGgggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatcctcgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19524 JY8QFUQ01DJT8W productive (see comment) Homsap IGHV3-11*04 F 997 96.71 206/213 nt 95.77 204/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 7 13 8.7.13 [1.16.37.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 65 of V-REGION: 3 nucleotides (from position 102 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcagtgactactacatgatctggatccgccaggctccagggaaggggctgagtgggtttcatacattactagtcgtggtactatcatgtacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19525 JY8QFUQ01CYYIV No results +19526 JY8QFUQ01CTCP4 productive Homsap IGHV3-7*01 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARERSAAGVVFFDFW in-frame - Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaggggctggagtgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgcaaatgaacagcctgcgagtcgaggacacggctgtgtatttctgtgcgagagagagatcagcagctggagtcgtcttctttgacttttggggccagggagccccggtcaccgtctccagagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19527 JY8QFUQ01BDDG4 unknown (see comment) Homsap IGHV3-7*01 F 918 91.71 199/217 nt 90.78 197/217 nt 7 8 X 7.8.X [1.17.38.X] null - No rearrangement found in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 56 to 57 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) cctctggatttacttttaaaactattggatgacctgggttcgccaggctccagggGAagggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagaggggtcgtattggcattatgataccttcggcactatttggggggccccgggaggtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19528 JY8QFUQ01B1Q9S productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 805 85.71 186/217 nt 84.79 184/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 7 7 9 7.7.9 [2.17.38.11] CTGLTYPDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) acgtctggatttaccttcagtaagttctgatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgnataatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19529 JY8QFUQ01CJ9NB productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19530 JY8QFUQ01A9QDL No results +19531 JY8QFUQ01A9DEW productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc +19532 JY8QFUQ01AIZUH productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19533 JY8QFUQ01AXYI6 No results +19534 JY8QFUQ01ARYZ1 No results +19535 JY8QFUQ01CAZ9T productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 719 97.37 148/152 nt 96.71 147/152 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 X 10 8.X.10 [1.14.27.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 53 of V-REGION: 66 nucleotides (from position 72 in the user submitted sequence), (do not cause frameshift) cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtggatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +19536 JY8QFUQ01CVSA0 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt 91.4 202/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 27 of V-REGION: 'C' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); tctctggCtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19537 JY8QFUQ01BXHJN No results +19538 JY8QFUQ01AYBIE productive Homsap IGHV4-61*02 F 830 85.97 190/221 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD4-11*01 ORF 2 10 7 15 10.7.15 [1.17.38.11] CARGFDYNKNRSDCDPW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcaggagtggacttaattcttggacatggatccggcagcccgccgggaagggactggagtggattgggcgtgtccatttcaatggaaacaccaactacaacccctccctcaggagtcgggccaccatatcattggacacgtccaagaaccagttctccctgcagatgacctctgtgaccgccgcggattcggccgtctattattgcgcgagaggttttgactacaataaaaatcggtccgattgcgacccctggggccagggaaccctggtcaccgtctcctcagcctccgaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccaccagcggccctgggctgcctggtcaaggactcttccccgaacggtgacggtgtcgtggcactc +19539 JY8QFUQ01CRDRV productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca +19540 JY8QFUQ01CKSXC unproductive Homsap IGHV3-7*01 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDGGVIVVVPMDYYGMDVW# out-of-frame + in FR3-IMGT at codon 86 of V-REGION: 'T' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); ctctggtttcacatttagtacgtactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcgagatggaactgagagtcattatgtggactctgtgaagggccgattcatcatctccagagacaactccaggaatTttactgtatctccaaatgaacagcctgagagtcgaagacacggctgtgtattattgtgtgagagatgggggtgttattgtagtagtgccaatggactattacggtatggacgtctgggggccaaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19541 JY8QFUQ01AN3OP unproductive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [1.17.38.11] CARDGPTLFIWKSW*F#FDQW out-of-frame + stop codons in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgGggtccgccaggctccagGggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggccccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19542 JY8QFUQ01CFWWG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 15 8.8.15 [1.17.38.11] CVRGGVSGAFRWGFDYW in-frame - cctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgacgacacggctgtttactactgtgtgagagggggagtcagtggggccttcaggtgggggtttgactactggggccagggaaccctggccaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19543 JY8QFUQ01A5NQZ productive Homsap IGHV3-66*02 F 913 91.67 198/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.17.38.11] CAKLADTGEWSNRIFYFW in-frame + gcctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19544 JY8QFUQ01A381T No results +19545 JY8QFUQ01B8JY3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 965 93.21 206/221 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD3-10*01 F 1 10 7 11 10.7.11 [1.17.38.11] CARLDAINWFDPW in-frame - tctctggtggcttcatcaccaataataatttctactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatcgattatagtgggagtaccgactacaacccgtccctcaggagtcgagtcaccatatccgtagacacgtccaagaaccagttcgccctgaggctgacttctgtgaccgccgcagacacggctatgtattactgtgcgagactcgacgcgataaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19546 JY8QFUQ01AWL6R No results +19547 JY8QFUQ01CRVVH productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctctggattcaccttcaatagatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaacactttgcagactccgtgaagggccgattcaccatctctagagacaattccaagaacactctgtatctgcaaatgaacagcctgagaattgaagacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca +19548 JY8QFUQ01CNZKS unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 2 8 8 X 8.8.X [1.17.38.11] CANASPRITGN#YFYYYGMDVW out-of-frame - in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagtagcGtatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactgggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19549 JY8QFUQ01B3B9N productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - tctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19550 JY8QFUQ01BQBH1 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 886 90.28 195/216 nt 89.35 193/216 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD3-16*01 F 2 7 8 10 7.8.10 [1.17.38.11] CAREVSDALDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 2 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) cctctggattcacctttgagatttggcatgagatgggtccgccaagtcccagggaaggggctacagtgggtGctctgggattaattggaatggtgctaaaacaggttatgcagcctctgtgcagggccgattcaccatctccagagacaacgacaacaacgtcctgtatctgcaaatgaacagtttgagacccgaggacacggccttgtatcgctgtgcgagagaggtttcggacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19551 JY8QFUQ01C26UN unproductive Homsap IGHV3-7*01 F 982 94.52 207/219 nt 94.06 206/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CARDPYNGGGYGAFDI## out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtaataattggatgagttgggtccgccaggctccagggaaggGggctggagtgggtggccaacatcaagcaagatggaagtgagaaagtctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgctaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagacccctataatggtggtggttatggtgcttttgatatctgggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19552 JY8QFUQ01BZEA2 unproductive Homsap IGHV3-11*01 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGGRLQV#YYYGMDVW out-of-frame + in CDR1-IMGT at codon 36 of V-REGION: 'AGTGGT' (6 nucleotides at position 21 to 26 in the user submitted sequence), (do not cause frameshift); tctctggtggctccatcaggAGTGGTagttactacatgagctggatccgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcatggtatacctggcagactctgtgaagggccgattcatcatctccagggacaacggcgagaactcactgtatcttcaaatgaacagcctgagagccgaagacacggccgtgtattactgtgcgagagatgggggacgactacaggtcgtactactatggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19553 JY8QFUQ01C9D90 unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 110 53.24 74/139 nt 10 7 X 10.7.X [1.17.11.X] null - No rearrangement found stop codons tctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19554 JY8QFUQ01A96ZV unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CATSRGSANWYPFDH## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactgggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19555 JY8QFUQ01AXT5V unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 985 95.37 206/216 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD2-8*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDGQRYCSNGVCSSFFDS## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19556 JY8QFUQ01BPQMT unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F 923 91.74 200/218 nt Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDRNNYYSDY## out-of-frame + cgtctggattcaacttcggaagttatggcatgcgctgggcccgccaggctccaggcaaggggctggagtgggtggcatttatttggtatgacggaagaaataaatattatgcagactccgttaagggccgattcaccatctccagagacaattccgagagcacactggatctgcaaatgaatagcctgagagccgaggacacggctgtctattactgtgcgagggataggaataattactactccgactactggggccaggggaaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19557 JY8QFUQ01C92PK productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctccctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +19558 JY8QFUQ01CBMVH productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 791 85.58 184/215 nt 84.65 182/215 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CATVRHLGERIFDFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'C' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift); tctctgggggCcaccatgagtagtttctactGggagctgggttcggcagtccccagggaggggactggagtggattggatttgtttcttacagtgggcccaccaactacagcccctccctcaagagtcgagtcaacttatcactggacgcggccaacaaacagttctctttgcagctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttccctctgagcctctgcagcacccagccagatgggaacgtggtccatcgcctgcctggtccagggcttcttccccc +19559 JY8QFUQ01BTLFM No results +19560 JY8QFUQ01DEHI7 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 390 75.18 106/141 nt 8 8 X 8.8.X [2.17.12.X] null - No rearrangement found Low V-REGION identity (75,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +19561 JY8QFUQ01BHD18 productive Homsap IGHV3-33*05 F 976 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CARDVYNSRTNYFDQW in-frame - gtctggattcaccttcagtaactatggcatncactgggtccgccaggctccaggcaaggggctggagtgggtggcacttgtcttaaatgatggaagtaatgattactatgcagactccgtgaggggccgattcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatgtctacaattcccgaactaattactttgaccaatggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19562 JY8QFUQ01B7TTO productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcaccctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcca +19563 JY8QFUQ01AUI48 productive Homsap IGHV3-11*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame + ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggctttcatacattagtggtagtggaactaccatatcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaggaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgaggcgggtgtggggatatagttatggttccgtttcgtactactttgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +19564 JY8QFUQ01ACN2Y productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 894 91.12 195/214 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [0.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + tggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19565 JY8QFUQ01B902J unproductive Homsap IGHV3-9*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDGSAIPVTGTYFEY## out-of-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtggatctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccaagggagccctggtcaccgtctcctcagcttccacaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19566 JY8QFUQ01C81S3 No results +19567 JY8QFUQ01CKMZ6 No results +19568 JY8QFUQ01BEFV1 productive Homsap IGHV3-7*01 F 1011 97.2 208/214 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [0.17.38.11] CSNGYGDFPRRW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggattcaccttcaggagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgacaaattctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19569 JY8QFUQ01BKHYH productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 15 10.7.15 [1.17.38.11] CARNPSYSNSHQHCDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'A' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaacagtggtagttactactggagttgggttcggcagcccgccgggaagggactggagtggattgggcgtatctacaccagtgggagcaccaactacaacccctccctcaagagtcgagtcgccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctaAtttttgtgcgagaaatccctcttatagcaattcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19570 JY8QFUQ01BBQBD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKSPLSVAGTRQ#NWFDPW out-of-frame - ctctgacttgcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19571 JY8QFUQ01A8GQZ No results +19572 JY8QFUQ01AE9OF productive (see comment) Homsap IGHV4-61*02 F (see comment) 783 84.79 184/217 nt 83.87 182/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 10 6 16 10.6.16 [1.17.38.11] CAIERSRSIGGDGQFDFW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 101 in the user submitted sequence), (do not cause frameshift) ctctggtggccccatcagaggcggtggtttctactggacctggctccggcagTccgccgggaaagggcctggagtggatcggacgtatttatgacagtggcagtgactacaatccttctctcaagagtcgagtcaccatgtcagtagacacgtccaagagccagttctccctgaggctgagttctgtggccgccgcagacacggccgtttacttctgtgcgatagaacgtagtagatcgattggcggagacggacaatttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +19573 JY8QFUQ01ADWU5 unproductive (see comment) Homsap IGHV4-4*07 F 844 88.32 189/214 nt 87.85 188/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 3 8 7 X 8.7.X [1.17.37.11] CARDSG##FDYW out-of-frame - stop codons in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 206 in the user submitted sequence), (cause frameshift) tctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtccaaaccagtgggaccccccactacaacccttccctnaagagtcgagtcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccattttttctgtgcgagagactccgggggactttgactactggggcccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19574 JY8QFUQ01CZ5RZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1053 98.62 214/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD5-24*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CARSQGFWYFDLW in-frame - ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtcgcatccattagtagtagtagtggttacatatactacgcagactcagtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatcgcagggattctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19575 JY8QFUQ01C3J0U unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.37.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 75 of V-REGION: 1 nucleotides (from position 128 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggcgattcaccatctccagagacaacgacagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19576 JY8QFUQ01AHEU2 No results +19577 JY8QFUQ01BHK93 productive (see comment) Homsap IGHV3-11*01 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.37.11] CARRRDYGDYGDGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 71 of V-REGION: 1 nucleotides (from position 121 in the user submitted sequence), (cause frameshift) cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaagggtctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggcccagggaaccctggtcacccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19578 JY8QFUQ01B1EY0 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19579 JY8QFUQ01A2DQ4 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 735 91.38 159/174 nt 90.23 157/174 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaagGgggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaaGgggccgattcaccatctccagagacaacgccaagaactcactgtatcttc +19580 JY8QFUQ01BMILN productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt 87.61 191/218 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 40 of V-REGION: 'T' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tccggaattcagatttcagtacttataacatgaaTttgggtccgccaggctcCcagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19581 JY8QFUQ01BIPS3 No results +19582 JY8QFUQ01DLD95 unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt 8 7 X 8.7.X [4.17.38.11] CARGGPTFMI (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggccccacttttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctactccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19583 JY8QFUQ01ASAYS unproductive Homsap IGHV3-11*01 F 862 89.67 191/213 nt 88.73 189/213 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD2-2*01 F 3 8 7 X 8.7.X [1.16.38.11] CARDPYCSSTNCYPY## out-of-frame - in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaagggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactgggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +19584 JY8QFUQ01DRBMX productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 950 93.12 203/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19585 JY8QFUQ01CNLWR productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatCgggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19586 JY8QFUQ01CLGST productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +19587 JY8QFUQ01CGUDC productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 826 86.04 191/222 nt 85.59 190/222 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [2.17.38.11] CVRHVRRFWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctctaatgggctccatcagcCggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19588 JY8QFUQ01B8S8S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtgcgtggaactca +19589 JY8QFUQ01CV5MF unproductive (see comment) Homsap IGHV4-4*07 F 1061 99.53 214/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctctggtggctccatcagtagtttctactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctgggggccgtggcacccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19590 JY8QFUQ01BNJLR No results +19591 JY8QFUQ01BIYVZ productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1004 95.87 209/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctcccaggagcaccctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcca +19592 JY8QFUQ01DKIFF unproductive Homsap IGHV3-33*04 F (see comment) 698 80.28 175/218 nt Homsap IGHJ5*02 F 101 67.35 33/49 nt Homsap IGHD1-7*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDILGLL# out-of-frame - Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release catttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttgggactactgggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19593 JY8QFUQ01A0GVR productive Homsap IGHV4-61*02 F 884 89.14 197/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.38.11] CARDFGGSYNLVAYW in-frame - tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19594 JY8QFUQ01DDQQ8 productive (see comment) Homsap IGHV1-2*02 F 939 93.46 200/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 82 to 87 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19595 JY8QFUQ01B20YK productive (see comment) Homsap IGHV3-7*01 F 891 90.32 196/217 nt 88.94 193/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARVNKDSTDMW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'GG' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtgactattggatgaggtggttccgccCagcctccaggaaagGGgggctggagtgggtggccagcataaAaagaagatggaagtgagaaaggttatgtggactctgtgaagggccgcttcaccatcgccagagacaacgcccagaaatcactgtttttgcagatgaacagcctgagaggcgaggacacggctgtgtatttctgtgcgagagtcaacaaggactctactgatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19596 JY8QFUQ01BUNBW No results +19597 JY8QFUQ01CIJBY productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19598 JY8QFUQ01ASB2P productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1047 99.07 212/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + ctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19599 JY8QFUQ01B38MC unproductive (see comment) Homsap IGHV3-7*01 F 941 92.66 202/218 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGHW in-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gctctggattcaacttcagaacctattagatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +19600 JY8QFUQ01BPG8K productive (see comment) Homsap IGHV4-61*02 F 885 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'CTGGTT' (6 nucleotides at position 21 to 26 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); ctccggtggctccatcagtaCTGGTTattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagagggggAcagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19601 JY8QFUQ01AOQJN productive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [1.17.38.11] CARVIPGRGNYAFDVW in-frame + ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19602 JY8QFUQ01CBZAJ unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 950 93.12 203/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgtccatagcatgaactgGggtccgccaggctccagGggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgaaagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19603 JY8QFUQ01A3YW3 No results +19604 JY8QFUQ01DWRYN productive (see comment) Homsap IGHV4-61*02 F (see comment) 700 79.73 177/222 nt 78.83 175/222 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-9*01 F 2 10 7 16 10.7.16 [2.17.38.11] CARERDRSIGGASELDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); gtctcttctgTgccccataagcagtggtggttactGattggaactggatccggcagcccgccgggaaggggctggagtggatcggacgtgttgacagtaatgggttcgtcaggtacaacagttccctcaagagtcgactttctatgtcggtggacatgtccaagagtcaggtctccctgaggttgaggtctgtgatcgccgcggacacggccgtatactattgtgcgcgagaacgcgataggtcgattggcggagcgtcagaacttgactcctggggccagggatctctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaggagcc +19605 JY8QFUQ01DM608 unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 121 96.15 25/26 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found ctccggggacagtgtctctaccaaca +19606 JY8QFUQ01A4NWM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKGDSGIRPIDYW in-frame + ctctggattcacctctagcgcctataccatgagttgggtccgccaggctccagggaaggggctggagtgcgtctcagctattagtggtggtggtactagcacatactacgcagactccgtgaagggccggttcaccatctccagagacacttccaagaacacactgtctctgcacctgaacagcctgagagtcgaggacacggccatatatttctgtgcgaaaggtgattctggtataagacctattgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctgcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaaggactacttccccgaaccggtgacggtgtcgtggaact +19607 JY8QFUQ01B1L0F No results +19608 JY8QFUQ01CQJB9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19609 JY8QFUQ01B9RBS productive (see comment) Homsap IGHV3-11*01 F 858 89.25 191/214 nt 88.79 190/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgtcgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19610 JY8QFUQ01BVGGJ productive Homsap IGHV3-48*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDRGGSAYPIFDYW in-frame + ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +19611 JY8QFUQ01BIRCP unproductive (see comment) Homsap IGHV3-48*01 F 1000 95.43 209/219 nt 94.98 208/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 X 8.8.X [2.17.38.11] CARERGKQLWR##DYW out-of-frame - stop codons in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaAaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtgggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19612 JY8QFUQ01BCOTN productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +19613 JY8QFUQ01CB3Z0 unproductive (see comment) Homsap IGHV3-33*05 F (see comment) 752 83.03 181/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CVKGTWIQ*LRP#DYW out-of-frame + stop codons Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaagggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19614 JY8QFUQ01DWXB5 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGGRGLR#DYW out-of-frame - cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagagggggacgggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19615 JY8QFUQ01A6RWA No results +19616 JY8QFUQ01AVEEC productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19617 JY8QFUQ01CZHGO No results +19618 JY8QFUQ01CYO65 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 842 87.61 191/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKQKHSYGYYFDQW in-frame - cctctggattcacgtttaaaacacatgccatgagctgggtccgccaggctccaggaaaggggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaaacatagttatggatactactttgaccagtggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19619 JY8QFUQ01CK4FL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKGIVGASMQADWFHPW in-frame - cctctggattcgtctttggcgactatgcgatgagctgggtccggcaggctccagggagggggctggagtgggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19620 JY8QFUQ01BYWI5 productive Homsap IGHV4-4*07 F 1061 99.53 214/215 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD4-11*01 ORF 2 8 7 13 8.7.13 [1.17.38.11] CARDFSNRGWYFDLW in-frame + tctctggtggctccatcagtagtttctactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +19621 JY8QFUQ01CK9QL No results +19622 JY8QFUQ01B0TQL productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19623 JY8QFUQ01A8226 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 840 90.24 185/205 nt 89.27 183/205 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.16.38.11] CARHPKSNVEGDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 9 nucleotides (from position 14 in the user submitted sequence), (do not cause frameshift)in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 44 in the user submitted sequence), (cause frameshift) tctctggtgactcccacttctggagctggatccggcagcccccgggaaagggctggagtggattggttatgtctataacagtgggaccaccaactacaacccctccctcaggagtcgagtcaccatgtctatagacacgtccaagaagcagatctctctgaggttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactcctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19624 JY8QFUQ01AGJTE No results +19625 JY8QFUQ01DQV12 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19626 JY8QFUQ01BVM72 productive Homsap IGHV3-11*01 F 1013 96.33 210/218 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD2-2*01 F 2 8 8 12 8.8.12 [1.17.38.11] CAVDCTSISCNGDW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctgggttcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggctttcatatattagtagtgctggtagtaccatatactacgcagactctgtgaggggccgattcaccatctccagggacaacaccaagaactcactgtatctgcaaatgaacagcctgagggccgaggacacggccgtgtattactgtgcggtagattgtactagtatcagctgcaacggagactggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19627 JY8QFUQ01B6H3W unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [2.17.38.11] CARPFSGRWCFDL## out-of-frame - Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattCaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgatccaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctgggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19628 JY8QFUQ01C2YVS productive (see comment) Homsap IGHV4-59*03 F (see comment) 728 82.33 177/215 nt 81.86 176/215 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD3-9*01 F 2 8 7 18 8.7.18 [1.17.38.11] CAREDPYFDILHLGSAIDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'C' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); tttctggtggctccatcagaagttactattggagttgggtccggcagtccccagggaCggggactggaatggattgggtacaagttctacagtgggcccgccaaatataatccctctctcgagggtcgagtcacaatttctatagacacgtcgaagagtcaattcttcctgaggatgacgtctgtcaccactgcggacacggccgtctattattgtgcgagagaggacccctatttcgacattttgcatctgggatcagcaatcgacccctggggccagggaatcccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaact +19629 JY8QFUQ01CCOGV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19630 JY8QFUQ01ACLBS unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaattacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19631 JY8QFUQ01BM2SX productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19632 JY8QFUQ01AY89G productive (see comment) Homsap IGHV4-61*02 F 857 87.78 194/221 nt 87.33 193/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 11 10.7.11 [1.17.38.11] CARSGWDNQFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggtgtcgccaccagtagtggcacttactactggagctggatccggcagtccgccgGgggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaacccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19633 JY8QFUQ01CLTY0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 928 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 79 to 81 in the user submitted sequence), (do not cause frameshift); gcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19634 JY8QFUQ01A06P5 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 716 81.19 177/218 nt 80.28 175/218 nt Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-3*02 F 1 8 8 X 8.8.X [1.17.38.11] CARIWDSWSGAF*CV# out-of-frame + stop codons Low V-REGION identity (81,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 15 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'AG' (2 nucleotides at position 50 to 51 in the user submitted sequence), (cause frameshift); cctctggattccccCTtttagtgtgtactggatgtactgggtccgccaaAGtccccgggaaggggcccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagctttttgatgtgtgggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc +19635 JY8QFUQ01CJSTZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19636 JY8QFUQ01BWMFB productive Homsap IGHV3-7*01 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + gctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19637 JY8QFUQ01CAU7V productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 776 83.71 185/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARQSEPANNFNDPSRYFFDTW in-frame + Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcccgtgtctccatttccattaatgattactactggggctggatccgccagcccccaggaaagccgctggagtggattgggactgtccattcccttgggtacaattacaacaacccgtccctcaagagtcgactcaccatttccgcagacacgtccaggaatcagatctccctgaaactgacgtctgtgaccgccgcagacacggctgtctatttctgtgcgagacagagcgagcccgccaataacttcaatgacccaagtcgttatttctttgacacttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +19638 JY8QFUQ01CXS49 productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame + ctctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19639 JY8QFUQ01CSKFG productive Homsap IGHV3-74*03 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + cctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19640 JY8QFUQ01C1ZFY unproductive Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGEGDPFF##YYSGLDVW out-of-frame - ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19641 JY8QFUQ01ANFV8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 7 12 8.7.12 [1.17.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccaatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19642 JY8QFUQ01COC7Y unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 459 72.78 131/180 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (72,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19643 JY8QFUQ01AF3MD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 797 85.32 186/218 nt 84.4 184/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDAGNTWPNYFDH## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); cctctggattcagctttttcaattatggGcatgaactgggtccgccaggctccagggaGgggggctggagtgggtcgcatttattagcggtgctggtgaaaatacttactacgcagactccgtgaagggccgattcgccatctccagagacgattcgagggacacactgtatctccaaatgagcagcctgagagccgaggactcggccctctattattgtgcgcgagatgcgggcaacacctggcccaactactttgaccactgggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19644 JY8QFUQ01CIVUV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 248 75.0 69/92 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 2 X X X X.X.X [X.X.30.11] CAKGIVGSFYAS##WFHPW out-of-frame - Low V-REGION identity (75,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgtctttggcgacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtggggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19645 JY8QFUQ01B72VY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19646 JY8QFUQ01BG4TP productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt 88.69 196/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 1 10 7 10 10.7.10 [1.17.38.11] CARHYGSSLDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tcgctggtggctccatcagcagtagtagttatgagtgggtctggattcgccagGcccccagggaagggactggaatggattggaaaaatctatcatagtgggaacacctactacaatccgtccctcaggagtcgagtcatcatgtcaatagacacgcccaagaaccagttctccctgaggatgaactctgtgaccgccgcagacacggctgtttattactgtgcgagacactatggcagcagccttgactcctggggccagggcatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19647 JY8QFUQ01B3R2B unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGAT#YW out-of-frame - tctccggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19648 JY8QFUQ01AQ0OL No results +19649 JY8QFUQ01DBODC unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 108 53.33 72/135 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons cctctggattcagtttcagagactatgccatgagttgggtccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19650 JY8QFUQ01CK99N unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKKTL*FGDLF#YNFDYW out-of-frame - stop codons cctctgggattcacctttagccactatgccgtgacctgggtccgccaggctccagggaagggtctggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaacattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19651 JY8QFUQ01B9WJA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagcccaaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +19652 JY8QFUQ01C7ZLN unproductive (see comment) Homsap IGHV3-33*05 F (see comment) 761 83.49 182/218 nt 82.57 180/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CVKGTWIQ*LRP#DYW out-of-frame + stop codons Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); cgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaGggggctggagtgggtggcgaccatttcatatgatattaataaaaaGatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaagggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19653 JY8QFUQ01AJEL4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 3 8 8 14 8.8.14 [1.17.38.11] CAKVGVMSARDRIDYW in-frame + cctctggattcacctttagcaactatgccatgagttgggtccgccaggctcaagggaaggggctggactgggtctcagatattagtaatagtggtggtgacacattctacgcaggctccgtgaagggccgcttcaccatctccagagacaattccaggaacactctatatctgcaaatggacagcctgagagccgaggacacggccgtgtattactgtgcgaaagtgggggtgatgtccgctcgagaccgcattgactactggggccggggaaccctggtctccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19654 JY8QFUQ01AHTOX productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 758 82.81 183/221 nt 82.35 182/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); gtctctgtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggGagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19655 JY8QFUQ01BYFAI productive (see comment) Homsap IGHV3-48*01 F 820 86.3 189/219 nt 85.84 188/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [2.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); tctctggctttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggGactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19656 JY8QFUQ01B6W63 No results +19657 JY8QFUQ01B43HS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKEIAVSGEGALDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); cctctggattcacAgtttagcaactatgccatgagctgggtccgccaggctccagggaaggggccggagtgggtctcagctattactggtcttgatggtagaacattctacgcagactccgtgaagggccgtttctccatctccagagacaattccaagaacacgttgtatttgggaatgaacagcctgagagccgaggacacggccgtatattattgtgcgaaagagatagcagtgagtggtgagggggcgttggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19658 JY8QFUQ01CQN0W unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 869 88.99 194/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - ctccgggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19659 JY8QFUQ01CHENJ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 595 82.66 143/173 nt 81.5 141/173 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found Low V-REGION identity (82,66% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); ctctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaGggggctggagtGgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgc +19660 JY8QFUQ01B93UC productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'GC' (2 nucleotides at position 12 to 13 in the user submitted sequence), (cause frameshift); ctctggattcaGCctttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19661 JY8QFUQ01B2E08 unproductive (see comment) Homsap IGHV3-7*01 F 841 87.96 190/216 nt 87.5 189/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD2-21*02 F 2 8 8 X 8.8.X [1.17.37.11] CGRDEGRRLAE#DSW out-of-frame + stop codons Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 190 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagcccgaggacacgggtgtgtattattgtggcagagatgaagggcgccgacttgccgaatgattcctggggcctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19662 JY8QFUQ01C32SR productive Homsap IGHV3-7*01 F 986 94.95 207/218 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDPYNGGGYGAFDIW in-frame - cctctggattcacctttagtaataattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacatcaagcaagatggaagtgagaaagtctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgcaaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagacccctataatggtggtggttatggtgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19663 JY8QFUQ01B00CV productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19664 JY8QFUQ01CLOHL unproductive Homsap IGHV3-30*10 F (see comment) 716 81.19 177/218 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD1-1*01 F 3 8 8 X 8.8.X [1.17.38.11] CSRGTTGTTDDSRLFQH# out-of-frame + Low V-REGION identity (81,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcggcaattacgccatgcactgggtccgccaggctccaggcaagggcctagagtgggtggctgtcataaataaggctgggaagactaaacattatatagactccgtgaagggccgattcaacgtctccagagacaactccgagaaaacactctatttggagatgaataacgtgggagttgaggacacggctgtatattattgttcgagaggtaccacggggacgacagacgactcgaggttgttccaacactggggcagggcgccctggtcaccgtttcgtcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +19665 JY8QFUQ01A0Z64 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGSYLYCFDYW in-frame - ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtggtgatgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactgctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19666 JY8QFUQ01CWEOH productive Homsap IGHV3-11*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame - ctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19667 JY8QFUQ01ABTHU productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDPYNGGGYGAFDIW in-frame + ctctggattcacctttagtaataattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacatcaagcaagatggaagtgagaaagtctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgctaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagacccctataatggtggtggttatggtgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19668 JY8QFUQ01CIF43 productive Homsap IGHV1-8*01 F 921 92.52 198/214 nt Homsap IGHJ3*01 F (see comment) 178 84.0 42/50 nt Homsap IGHD2-2*02 F 3 8 8 14 8.8.14 [0.17.38.11] CARLAAPLRAYALDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tggatacaccttcggcagttttgatatcaactgggtgcggcaggcccctggacaagggcttgagtggatggggtggatgaaccctcacagtggtaacacaggatatgcagagaacttccagggcagagtcaccatgaccagggacacctccataaacacagcctacatggagctgagcagcctgacatctgacgacacggccatatattactgtgcgagactagcagcacctttacgcgcctacgctttggacgtctggggccaagggaccgcggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +19669 JY8QFUQ01CE2Z4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19670 JY8QFUQ01CQQDK productive (see comment) Homsap IGHV3-7*01 F 932 92.2 201/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); cctctggattcacctttagaagctatgccatgacctgggttcgccaggctccagggaaGggggctggaatgggtggGccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19671 JY8QFUQ01B6IHX productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 851 88.07 192/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-2*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDRTLHTPAQMFYYGMDVW in-frame + catctggattcaccttcagttcttatagtgtaaactgggtccgccaggctccagggaagggcctagagtttgtctcatacattgatagtagtggttctaccatatactacgcagactctgtgaagggccgattcaccatctctagagacaatgcccagaactcactgtttctgcaaatgaacaacctgcgagtcgacgacacggccgtatattactgtgcaaaagaccggacacttcacacacccgctcagatgttttactatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatctccgaccagccccaaggtcttcccgctgagcctctgcagcacccagctagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19672 JY8QFUQ01BOX74 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 869 88.99 194/218 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD6-25*01 F 3 8 8 15 8.8.15 [1.17.38.11] CVRGGRGQQREDAFDIW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctctggattcatcttcagtagttatagtttgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatatgagtagttcttacatctattatggagactcagtgaggggccgatttaccatctccagagacaacgccgagagttcactgtatctgcagatgagcagcctgagagccgaggacacggctttatattattgtgtgagaggcgggagggggcagcagcgagaagatgcttttgacatttggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19673 JY8QFUQ01C3MBF productive (see comment) Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 99.54 215/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagGggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19674 JY8QFUQ01CIXOC unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 851 88.07 192/218 nt Homsap IGHJ2*01 F 175 81.13 43/53 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CARQRGHSSSY#WSFDLW out-of-frame - catctggatacagctttacctccacatggatcggctgggtgcgccaggtgcccgggaaaggcctggagtggatgggtatcatctatcctggcaactctgaaaccaagtatagcccgtccttccaaggccgggtcgccatgtcagtcgacaagtccatcactaccgcctacctgatatggggcggcctgaaggcctcggacaccgccatgtattactgtgcgagacaacgaggccacagcagttcctacttggtccttcgatctctggggccgtggcacccaggtcatagtcaactcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19675 JY8QFUQ01COB1R unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 920 90.95 201/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-8*02 F 2 10 7 X 10.7.X [1.17.38.11] CARLTDWWG##FDHW out-of-frame + stop codons tctctggtggctccatcagcggtacttctcattactggggctgggtccgccagcccccagggaaggggctggagtggattggcagtatctactctggtgggaccacctactacaacccgtccctcaagagtcgactcaccatgtccgtcgacacgtccaagaaccagatgtccctgcggctgagctctgtgaccgccgcagacacggctgtctattactgtgcgagactgacagactggtggggggcactttgatcactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +19676 JY8QFUQ01AZ7JA No results +19677 JY8QFUQ01CU3VO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 841 87.96 190/216 nt 87.5 189/216 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD2-8*01 F 1 8 8 19 8.8.19 [1.16.38.11] CAKVFQVSGEHHFYYYGMNAW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcatctttagtaattatgccatgagttgggtccgccaggccccagggaggggctggagtgggtctcaactatcagtgccaatggagacaacacatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacagtgtatatgcaaatgaacagcctgaaagccgaggagacggccgtctatcattgtgcgaaagtcttccaggtgtctggcgaacatcacttctactactatggtatgaatgcctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtatcgcctgcctcggtccagggcttcttcccccca +19678 JY8QFUQ01BEJCA productive Homsap IGHV3-48*02 F (see comment) 694 79.91 175/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD7-27*01 F 1 8 8 12 8.8.12 [2.17.38.11] CATDPNGDLDFDYW in-frame + Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctccggattcatccccagtaactacggcatgaactgggtccgccagactccagggaaggggctggagtggattgcacacatcagtcacactggtgatggcacactttacgcagactctgtgaagggccgattcgccatctccagggacagttccaggacatcatattatttgcacataagtagcctgagagacgaggacacggctgcatattattgtgcgacagatccaaatggggacctagattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggttgtcgcatgcctggtccagggcttcttccccca +19679 JY8QFUQ01AKN9T productive (see comment) Homsap IGHV1-2*02 F 939 93.46 200/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 82 to 87 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19680 JY8QFUQ01ATQQZ unproductive Homsap IGHV1-18*01 F 867 89.72 192/214 nt Homsap IGHJ5*01 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [0.17.38.11] CARGSGTSQNGMDV## out-of-frame - tggttacgcctttagcacctatgacatcagttgggtgcgacaggcccctggacaagggcttgagtggctggcctggatcagcacttatggtggtaacacaaattatgcacagctgctccagggcagagtcaccgtgaccagagacacatccacgagcacagccttcatggaactgaggagtctaagatctgacgacacggccgtgtattactgtgcgagagggagtgggacctcccaaaatggtatggacgtctgggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19681 JY8QFUQ01CIISY No results +19682 JY8QFUQ01B7K2X unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F (see comment) 674 79.53 171/215 nt 78.14 168/215 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [0.17.38.11] CARERRPGVAIQMATTI#YGMDVW out-of-frame + Low V-REGION identity (79,53% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 177 to 177 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 213 to 213 in the user submitted sequence), (cause frameshift); cctctgatacaattagtcgttatggcatgcactgggtccgccaggctccaggcaaggggctggagtggctggcaattatttcatatgatggaaataggatatatgttggagactccgtgaagggccgcttcaccgtttccagagacaacgccgggaggactctgTtttctgcaaatTgaacagtctgagaggtgatgacaccgccacatattTtttgtgcgagagagcggcgtcccggggtggctatccaaatggctaccaccatttttacggcatggacgtctggggccaagggaccagggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaccagtgcgacggcgtgtcgtggaaact +19683 JY8QFUQ01A0OLH No results +19684 JY8QFUQ01DM7GD productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 692 80.47 173/215 nt 80.0 172/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctgggttcaccatcagtcactactccatggcctGgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +19685 JY8QFUQ01CY6SK productive (see comment) Homsap IGHV3-7*01 F 923 91.74 200/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 76 of V-REGION: 'T' (1 nucleotides at position 132 to 132 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 171 to 171 in the user submitted sequence), (cause frameshift); tctggagttcaggctttagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaaatactatgtggactctgtgaagggccgaTttcaccgtctccagagacaacgccaagaactcactgttTtttgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgattagtagtgatttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +19686 JY8QFUQ01C1RQB productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19687 JY8QFUQ01AC4M1 productive (see comment) Homsap IGHV3-30*12 F, or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 570 89.44 127/142 nt 88.73 126/142 nt Homsap IGHJ4*03 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 X 16 8.X.16 [1.4.34.11] CARWGYFGSGSYWDLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 43 of V-REGION: 75 nucleotides (from position 41 in the user submitted sequence), (do not cause frameshift) gtctggattcagcctcagtagccatggcatacactggactcccatgaagggccgattcaccgtctccagagacaattccatgaacacactgtatctgcacatgaacagcctgagagtcgaggacacggctatgtattactgtgcgagatggggatattttggttcggggagttattgggatctcgactactggggcctggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19688 JY8QFUQ01CLJDU productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 795 84.3 188/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 10 15 8.10.15 [1.17.38.11] CTTDSFHIAVHGVFDFW in-frame + Low V-REGION identity (84,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttctgcattcatgttcaacaaagcctggatgaattgggtccgccaggctccaggaaagggactggagtgggttggccgtattaaaagtaacggcgacggtgcgacagtcgactacgctgcacccgtgaaaggccgattcaccatctcaagagatgattcacagaataccctcttcttacaaatgagcagcctgaaagccgaggacacagccgtctattattgtaccacagatagcttccatattgcagtgcatggcgtctttgacttctggggccagggagccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +19689 JY8QFUQ01B78CT unknown (see comment) Homsap IGHV3-7*01 F 918 91.71 199/217 nt 90.78 197/217 nt 7 8 X 7.8.X [1.17.38.X] null - No rearrangement found in FR3-IMGT at codon 98 of V-REGION: 'G' (1 nucleotides at position 197 to 197 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) cctctagattcacctttaatggtactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgagGgacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactgggggccagggaacccctggtcctcgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +19690 JY8QFUQ01CG2OW unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame + ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +19691 JY8QFUQ01BSB9L productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 837 87.56 190/217 nt 86.64 188/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'T' (1 nucleotides at position 140 to 140 in the user submitted sequence), (cause frameshift); ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatatacgcggactccgtaAaagggccggttcaccatTttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19692 JY8QFUQ01AAUWG productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARLPNTIDSW in-frame + Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) ttctggatatagttttgccacctactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatgggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatttcagccgacaagtccctcagtatcgcctacctgcagtggagcagcctgcaggcctcggacaccgccatatattactgtgcgagactgcctaacactattgactcctggggccaggggaccctggtcaacgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19693 JY8QFUQ01BIGM6 productive Homsap IGHV1-2*02 F 827 87.44 188/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame + ctggatatactttcaccgaccattatgtttactggatgcgacaggcccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19694 JY8QFUQ01AR363 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 111 56.19 59/105 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons cctctggattcaccttcagtcgttatagcatgaactgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19695 JY8QFUQ01BYPOG productive (see comment) Homsap IGHV4-4*07 F 813 86.92 186/214 nt 86.45 185/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgCaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19696 JY8QFUQ01BP3GN productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 979 95.77 204/213 nt 93.9 200/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 3 8 7 11 8.7.11 [1.16.38.11] CASLHPTEERDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 2 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) tctatggtgagtcctTtcagtggCatactactggagctggatccgccagcccccggaaggggctggagtggattggagaaatcCaatcatagtggaagcaccacctacaacccgtccctcaagagtcgagtcaccatatcaatagacacgtccaacaaccagttctccctgaggctgagctctgtgaccgccgcggacacggctttttattactgtgcgagccttcaccccacagaggaaagggactactggggccagggaactctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19697 JY8QFUQ01BBOTL productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1000 93.42 213/228 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [2.17.38.11] CARGSSRGGRSDVNYYELDFW in-frame + tctccgggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtcctcatcgagaggcctcgagtggctgggaaggacatactacaggtccaagtggtattatgactatgcagtgtctgtccaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagctgaattctgtgactcccgaggacacggctgtgtattactgtgcaagagggtccagccgcggggggagatctgatgtgaactactatgagctggacttctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +19698 JY8QFUQ01C7FF1 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 7 10 9.7.10 [1.17.38.11] CASHGGKYFPQW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcCccccagggaaggggctggagtggattggacaaatccatcatggtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +19699 JY8QFUQ01A61VS productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 880 88.74 197/222 nt 86.49 192/222 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [2.17.38.11] CARQLSGDYASFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'C' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'G' (1 nucleotides at position 172 to 172 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'T' (1 nucleotides at position 197 to 197 in the user submitted sequence), (cause frameshift); gtctctggtgcctccatcaccCagtggtactttttactggggCctggatccgccagcccccagggaAaggggctggagtgggttggcaatatctattctagtggtgtcgcctattacaacccgtccctcaagagtcgagtcaccatgtccgtcgacacgtccaagaatgagGttttccctgacactgacctctgtgTaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19700 JY8QFUQ01DB7BX productive (see comment) Homsap IGHV3-33*05 F (see comment) 767 83.26 184/221 nt 82.35 182/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.17.38.11] CVKGRGYNDYGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); cagcgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtAgggtggcgaccatttcatatgatAttaatgaaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +19701 JY8QFUQ01CKQX2 No results +19702 JY8QFUQ01ASJWX unknown (see comment) Homsap IGHV4-61*04 F (see comment) 311 60.37 131/217 nt 59.91 130/217 nt 10 7 X 10.7.X [1.17.37.X] null - No rearrangement found Low V-REGION identity (60,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); tgtctggtggctccgtcagcagtgGgaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaaccccctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +19703 JY8QFUQ01AUMIA No results +19704 JY8QFUQ01CZTM0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19705 JY8QFUQ01CPO7R productive (see comment) Homsap IGHV3-7*01 F 964 93.61 205/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); gcctctggattcacatttagtGaattattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19706 JY8QFUQ01B4A7K productive (see comment) Homsap IGHV4-39*02 F (see comment) 772 83.33 185/222 nt 82.88 184/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 10 7 22 10.7.22 [2.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); gtctccggtgtctccattagtagtgataCtttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19707 JY8QFUQ01BGKHN unknown (see comment) Homsap IGHV4-61*02 F (see comment) 522 70.97 154/217 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (70,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19708 JY8QFUQ01A88CH No results +19709 JY8QFUQ01CE67S productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaactcag +19710 JY8QFUQ01DDASA No results +19711 JY8QFUQ01BOQD6 productive (see comment) Homsap IGHV4-61*01 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtggtagCttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +19712 JY8QFUQ01BKXOR unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 204 60.87 84/138 nt 8 7 X 8.7.X [2.17.12.X] null - No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BKXOR ; 8 AA in Homsap_IGHV3-74*01), and low V-REGION identity (60,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacaggcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +19713 JY8QFUQ01BLQL8 No results +19714 JY8QFUQ01DS502 productive Homsap IGHV2-5*05 F, or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F 1058 92.65 227/245 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 3 10 7 12 10.7.12 [9.17.38.11] CGHMDQWLATFDFW in-frame - agaccctcacgctgacctgcaccttctctgggttctcactcagcaccagtggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcactcatttattgggatggtgataagcgctatgacccatctctgaggaatagactcaccatcaccaagaaaacttccaaaaatcaggtggtccttaccatgacttccctggaccctgtggacacagccacatatttctgtggacacatggaccagtggctggcgacttttgacttctggggccagggtatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctcccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19715 JY8QFUQ01CLACL unproductive Homsap IGHV3-7*01 F 837 87.56 190/217 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CGRDERGADLPNDS## out-of-frame + ctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagccccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctggggccctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19716 JY8QFUQ01BBZX9 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame + cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19717 JY8QFUQ01AULAR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame + ctctggattcaactttggcatctataccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19718 JY8QFUQ01ATM3Z unproductive (see comment) Homsap IGHV3-7*03 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [2.17.38.11] CVDIRLGDWFFDLW in-frame - stop codons in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtgactattggatgagctgggtccgccaggctccagggaaggggctagagtgggtggccaacataaaataGagatggaagtgagcaacactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagagctcactgtatctgcaaatgaacggcctcagagtcgaggatacggccgtctattactgtgtcgacataagactgggtgattggttcttcgatctctggggccgtggcaccctggtaactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19719 JY8QFUQ01BIKKF productive (see comment) Homsap IGHV4-4*07 F 863 89.3 192/215 nt 88.37 190/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 7 9 8.7.9 [1.17.38.11] CARDSGDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'T' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); tctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtccaaaccagtgggagCcccccactacaacccctTccctcaagagtcgagtcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccatttttttctgtgcgagagactccggggactttgactactggggcccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19720 JY8QFUQ01DQIKZ productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19721 JY8QFUQ01C519L unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt 83.87 182/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-25*01 F 1 8 7 X 8.7.X [2.17.38.11] CGKDVRGGLSLEEATKLPPP*LL# out-of-frame - stop codons in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 89 in the user submitted sequence), (do not cause frameshift) gcctctcgggttctccttcagtgcctatgccatgacctgggtccgccaGggctccagggagggggccggagtgggtctcgtctattagcagtggtagtttaacacattacgcagactccgtgaGggggccgattcaccgtctccagagacaattccaagagcactctgtttctgcaaatggacagcctgagaaccgaggacacggccgtatattactgtgggaaagatgttagaggcggtctcagtctggaagaggctactaaactaccccccccctgactactgggggccagggaaccctggtcaccgtctcctcagcctccatcaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +19722 JY8QFUQ01ANX1P unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 858 89.25 191/214 nt 88.79 190/214 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD6-6*01 F 2 10 7 X 10.7.X [1.17.37.11] CARGGIYL*QPV# out-of-frame + stop codons The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01ANX1P ; 8 AA in Homsap_IGHV4-59*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 92 of V-REGION: 1 nucleotides (from position 184 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagcggcagtaccaactactggacctggatccggcagcccccaggaaagggactggaattcattgggtatatctataacagtggcaacaccaactacaacccctccctcaagagccgagtctccatttctttggacaggtccaagaaccagttctccctgaggctgaccccgtgaccgctgcggacacggccatgtattactgtgcgagggggggcatatacctatgacagcccgtgggggccagggaacccgggtcaccgtctcctcggcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga +19723 JY8QFUQ01CVDNM unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 828 87.1 189/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGFSAWGQDAFDI## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttgggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19724 JY8QFUQ01BZB9T productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 885 90.65 194/214 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARTEYVSGWYIGGFDPW in-frame + ctatggtgggtcactcagttcttatttctggagctggatccgccagtccccagagaaaggactggagtggattggggaaatcaatcagagtggaaccaccaactacaacccgtctctcaggagtcgagtcaccatagcaatagacacgtccaagaaccagttctccctgaaggtgacctctgtgtccgccgcggacacggctgtctattactgtgcgaggaccgagtatgtcagtggctggtacatcggggggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +19725 JY8QFUQ01BFI4C productive (see comment) Homsap IGHV3-7*01 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [2.17.37.11] CARTSSREITDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 170 in the user submitted sequence), (cause frameshift) gcctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19726 JY8QFUQ01B5Z84 productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc +19727 JY8QFUQ01A2OMT productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + gttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctcccaccgaacgggcccatcggtcttccccctggcaccctcctccaagagcaccctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19728 JY8QFUQ01A4PI2 unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 819 86.18 187/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19729 JY8QFUQ01C9VEQ No results +19730 JY8QFUQ01BZZZ2 productive Homsap IGHV3-49*02 F, or Homsap IGHV3-49*03 F or Homsap IGHV3-49*04 F or Homsap IGHV3-49*05 F (see comment) 457 83.33 110/132 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD3-3*01 F 2 X 6 16 X.6.16 [X.X.38.11] CARDRDYHDSWPDSFDVW in-frame + Low V-REGION identity (83,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcttctggattcaccttagaatacgccgcgtctgtgaaaggaagattcaccatctcaagagatgactccgagggcatcgcccacctagagatgaacagtctcaacaccgaggacacagccgtgtattattgtgctagagaccgcgattatcacgatagttggcccgattcttttgatgtctggggcccagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccga +19731 JY8QFUQ01DHZ1T unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 88 51.91 68/131 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcatcttcagtgactactacatgacctggatccgccaggctccaaggtcttcccgctgagcctcgacaacacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19732 JY8QFUQ01CANC3 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 892 89.95 197/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [2.17.38.11] CARDPSGSGWAFESW in-frame - gcgtctggattccctttcagtagagatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatggtatggtatgatggaagtaatacacaccatgcagattccgtgaagggccgattcatcatttccagagacaattccaagaataaagtgtatctgcaaatgaacagtctgagagacgaggacacggctgtctattattgtgcgagagatccgagcggcagtggctgggcctttgagtcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +19733 JY8QFUQ01CT2F5 unproductive Homsap IGHV3-30*16 F 909 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD1-7*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDELPWDTIEYYFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'T' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); ctctggattcaacttcaggacctattctatgcactggctccgccaggcTcccaggcaagggactagagtgggtatcagttaTtttcatatgatggaactaagaagaattatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctacaaatggacagcctgagacctgaggacacggctgtgtattactgtgcgagagatgaactgccttgggatacaatagagtattactttgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagctctgcagcacccagccagatgggaacgtggtcatcacctgcctggtccagggcttcttccc +19734 JY8QFUQ01DL8K2 productive (see comment) Homsap IGHV3-9*01 F 910 90.87 199/219 nt 90.41 198/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD3-22*01 F 2 7 8 22 7.8.22 [2.17.38.11] CVRQAYYHDSSAYFFSRYWYFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift) agcctctggattcactttgatgactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacgccaagaagtccctgtttctgcaaattaaaagtctgagagttgaggacacggccttatattattgtgtgaggcaagcgtattaccatgatagcagtgcttacttcttctcccgctactggtacttcgatctctggggccgtggcaccccggtcactgtctcttcagccctccaccaaggggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19735 JY8QFUQ01CDPNG unproductive (see comment) Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKRRVGDTSDWY#YFEYW out-of-frame + stop codons cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19736 JY8QFUQ01B1L81 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 89.3 192/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKNNNDFGDYDWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagttcctactggagttggatccggcagCcccccagggaagggcctggagtggattggttatgtctattatactggGgggcaccgactccaaccCcctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19737 JY8QFUQ01A3A5F productive Homsap IGHV1-8*01 F 840 87.85 188/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARVGGTHYHYGVDVW in-frame + cggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagatctgacgacacggccgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgtccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19738 JY8QFUQ01CHB9V unproductive (see comment) Homsap IGHV1-18*01 F 943 93.9 200/213 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt 8 8 8 8.8.8 [X.17.38.11] CARGDYFDH* in-frame - stop codons ggttacacctttaccagctatggtctcagctgggtgcgacaggcccctggccaagggcttgagtggatgggatggatcttcgtttttaacggtaacacaaaatatgcacagcacctccagggcagagtcaccatgaccacagacacatccacggacacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagaggtgactactttgaccactagggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19739 JY8QFUQ01B3MM5 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19740 JY8QFUQ01C3SNK productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19741 JY8QFUQ01CAJS1 productive (see comment) Homsap IGHV3-48*01 F 985 95.37 206/216 nt 94.44 204/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); tctggtttcaccttcaggagctctggcaGtgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaAaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19742 JY8QFUQ01CGUEK No results +19743 JY8QFUQ01CI0GE unknown (see comment) Homsap IGHV3-7*02 F 108 59.26 48/81 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +19744 JY8QFUQ01A9PH6 productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1018 96.35 211/219 nt 95.89 210/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDLYDSSGSFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGccttcagcagctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtaggagtagtaccaaaaactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgcgagagatttgtatgatagtagtggttcttttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttctccgaaccggtgacggtgtcgtggaactcag +19745 JY8QFUQ01CSXT8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 783 84.79 184/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDPFIAATGRP#YFEYW out-of-frame - Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggactcaacattggcaactatgacatgacctgggtccgccaggctcctgggaaggggctggagtgggtctcaagtattggaactactgagggtagctcatattatgcagactccgtgaagggccgattcaccatctccagagacaatgccaaaaacacgctgtatctgcaattgaacagcctgagaagtgaagacactgctgattactactgtgcgaaagacccatttatagccgcaactggccgccctggtactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19746 JY8QFUQ01CB3LZ productive (see comment) Homsap IGHV3-74*03 F 847 87.67 192/219 nt 86.76 190/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); gcctctggattcacgtttcCacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaAagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19747 JY8QFUQ01AMBU7 productive (see comment) Homsap IGHV3-7*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaAaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +19748 JY8QFUQ01C1BLG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19749 JY8QFUQ01CI2JP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 913 91.67 198/216 nt 90.74 196/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.16.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'GC' (2 nucleotides at position 48 to 49 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagGCtccgagggaaggggctggttgggtctcacgtgttaatggtggatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagtcccaaggtcttcccgctgagcctcgacagccaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +19750 JY8QFUQ01BX9XW unproductive Homsap IGHV1-2*02 F 921 92.52 198/214 nt 91.12 195/214 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [0.17.38.11] CVRDEFRKKWEPDSDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 35 of V-REGION: 'T' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); tggatacacgttcaTcagcctactatatgcCagtgggtgcgacaggGcccctggacaagggcttgagtggatgggatggatcaaccctgacagtggtggcacagagtatgcagagaagtttcagggcagggtcaccatgaccagggacacgtccgtcagtacagtctacatggagctgaagaacctgagatctgacgacacggccgtctattactgtgtgagagatgaatttcgaaagaagtgggagcccgactctgactactgggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19751 JY8QFUQ01B4DWA productive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*11 F or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 854 88.84 191/215 nt 87.91 189/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 17 8.8.17 [0.17.38.11] CASDREDTAMITAESFNIW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); ctggaggcaccttcagtagacatgctatcaactgggtgcgacaggcccctggacaagggcttgagtggatgggagggatcaaccccaCtccttcatacaAccaaaatatgcacagaggttccagggcagagtcacatttaccgcggacgaatccacggccacagtctacatgcaactgagcagcctgggatctgaagacacggccgtctattattgtgcgagcgatcgggaagatacagctatgattaccgcggagagttttaatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +19752 JY8QFUQ01BP0GT unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 926 90.62 203/224 nt Homsap IGHJ4*03 F (see comment) 78 62.5 30/48 nt Homsap IGHD3-22*01 F 3 8 10 X 8.10.X [1.17.38.11] CATDRPYYKNAAGRLWYYYGMDVL## out-of-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) tctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaacgctgctggccgactctggtattactacggtatggacgttttgggggcccaaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19753 JY8QFUQ01BWDBU unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDTLEVVSNMDDAFDL## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggcccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19754 JY8QFUQ01B6LPS productive (see comment) Homsap IGHV3-48*01 F 1080 100.0 217/217 nt 99.54 216/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatagcatgaactgggtccGgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19755 JY8QFUQ01CU62M productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.16.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 51 of V-REGION: 2 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggttggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +19756 JY8QFUQ01AW4XS unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 406 89.11 90/101 nt 8 7 X 8.7.X [1.17.X.X] null - No rearrangement found cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagggtgttgaca +19757 JY8QFUQ01DIUSB productive Homsap IGHV3-21*04 F 995 95.41 208/218 nt Homsap IGHJ5*01 F (see comment) 111 68.63 35/51 nt Homsap IGHD6-13*01 F 1 8 8 11 8.8.11 [1.17.38.11] CAERPFRIRLDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcggagcgtccgttcagaatcaggttggacgtctggggccaaggggaccacggtcacgtctcctcagcatccccggaccagcccctaaggtcttcccgctgagctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19758 JY8QFUQ01AL3F7 No results +19759 JY8QFUQ01CHPXI No results +19760 JY8QFUQ01B0BDK productive Homsap IGHV3-11*01 F 887 89.91 196/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-7*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARGKGKGGTTYYGMDVW in-frame - cctctggattcactttcagtgactactacatgaattgggtccgccaggctccagggaagggcctggagtggctttcatacattactgcaagtggtgccatcatacactatgcagactctgtgaagggccgattcatcatctccagggacaacgccaagaactcactgtctctgcagatgaacagcctgagagccgacgacacggccgtctattattgtgctcgggggaagggcaagggtggaactacctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19761 JY8QFUQ01A2HPP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19762 JY8QFUQ01BHZC2 No results +19763 JY8QFUQ01C3WSP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19764 JY8QFUQ01DFGZR productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19765 JY8QFUQ01C5JVO productive Homsap IGHV4-61*02 F 1037 96.83 214/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARGPKYYYDSSGFEDLW in-frame - tctctggtggctccatcagcagtggtcgttactactggagctggatccggcagcccgccgggaagggactggaatggattgggcgtatttataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagctctccctgaagttgagttctgtgaccgccgcagacacggccgtatattactgtgcgagaggtcccaagtattactatgatagcagtggtttcgaagacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19766 JY8QFUQ01DV1WY unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found ctctggattcatcttcagtagctactggatgcactggg +19767 JY8QFUQ01BPAPP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagctcgacagcacccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +19768 JY8QFUQ01AYRAD productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19769 JY8QFUQ01AT1U6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1023 94.32 216/229 nt Homsap IGHJ2*01 F 103 66.04 35/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [5.17.38.11] CAKVVWSLWYFDLW in-frame - ctcctgtgcagcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcacccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19770 JY8QFUQ01B3W6V productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 994 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKDKWYYDSSGYQYYLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctntggattccCcctttagcaactatgacatgaattgggtccgccaggctccagggaaggggctggagtgggtctccggtattagtggtagtggcggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctggatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagacaaatggtactatgatagtagtggttatcaatactaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19771 JY8QFUQ01AD3NZ unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.74 200/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKKYHYGSGYLLVLF*LL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggtacttacttgtactattttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19772 JY8QFUQ01BCT61 productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 668 79.72 169/212 nt 79.25 168/212 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [0.17.38.11] CVRDAETTVSGVAGWFDPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) ctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19773 JY8QFUQ01BHVEV productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 748 82.65 181/219 nt 81.28 178/219 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD2-21*01 F 3 8 8 17 8.8.17 [2.17.38.11] CAMRLFVVVLSATLILTTG in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 90 of V-REGION: 'G' (1 nucleotides at position 176 to 176 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'AT' (2 nucleotides at position 215 to 216 in the user submitted sequence), (cause frameshift); gcctctgggttcacattcagtaactactGggatccactgggtccgccaagctccaggaaaggggctagagtgggtcgcacgtattaatgatgctggaaagcgtgccgacttcgcgactttcgtgaagggccgattctccatctcccgagacaatgccaagaacacagtgtatctgGgaaatgactagtctgagagtcgacgacacggctgtctaATtttttgtgcaatgcgactttttgtggtggtcctgagtgctacccttatcttgacaactgggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19774 JY8QFUQ01ANO71 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 915 90.91 200/220 nt 90.45 199/220 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); agcctctggattcgccttcagttggtattggatgcactgggtccgccaagctccagGgggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19775 JY8QFUQ01C98IO productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 906 92.42 195/211 nt 91.0 192/211 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 7 8 13 7.8.13 [X.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 28 in the user submitted sequence), (cause frameshift) ggatcacctttggttattGatggcatgactgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19776 JY8QFUQ01CE5JH productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 768 82.96 185/223 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 13 8.10.13 [1.17.38.11] CATDSPTGYYAFDVW in-frame - Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctgggttcgttttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19777 JY8QFUQ01A004N productive (see comment) Homsap IGHV4-39*02 F 920 90.95 201/221 nt 90.05 199/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 3 10 7 14 10.7.14 [1.17.38.11] CARPGARETNNAWVDW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagtaggagtgcctactactggggctggatccgccagcccccagggaaggggctggagtggattgggaccatctattatagtGgggaccacatactccaatccgtcCcctcaagactcgagtcaccatgtccttggacacgtccaagaaccacatctccctgaagctgaattctgtgaccgccgcagacacggctgtttattactgtgcgagacctggggctagggagactaataacgcctgggtcgactggggccagggcaccctggtcaccgtctcctcggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19778 JY8QFUQ01CLY7N productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 8 8 8.8.8 [1.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19779 JY8QFUQ01CGSBA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19780 JY8QFUQ01B3134 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 833 87.16 190/218 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARLRSFGDYPLDVW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19781 JY8QFUQ01BNPXL productive (see comment) Homsap IGHV3-23*03 F (see comment) 531 71.89 156/217 nt 70.97 154/217 nt Homsap IGHJ2*01 F 166 79.25 42/53 nt Homsap IGHD3-3*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARVRNSNWYFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (71,89% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 71 of V-REGION: 'TA' (2 nucleotides at position 121 to 122 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); ctctgaagacatgtttaagagtttcggattgacgtgggtccgtcaggctccagggaaggggctggagtgggtcgcaggaataaacaattacaatggtgcaactttctatgctggccccgtTAaaagggccgcttcaccgtctctcgagataaagaaaagaccacttTtttatctacaaatggacaacgtgagggtcgacgacacgggcgtttatttctgtgcgagagtcaggaatagtaattggtacttcgaccactggggccgcggcgcactagtcacagtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19782 JY8QFUQ01CMUST unproductive (see comment) Homsap IGHV4-61*01 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*03 F 123 72.92 35/48 nt Homsap IGHD3-22*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARDGNERLLLF*NL in-frame + stop codons Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatgagaggttattactcttttgaaacctgggccgagggacattggtcaccgtctcctcagctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaaggactacttccccgaaccggtgacggtcgtcgtggaactc +19783 JY8QFUQ01CCV7N productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 775 84.02 184/219 nt 83.56 183/219 nt Homsap IGHJ3*02 F (see comment) 142 76.0 38/50 nt Homsap IGHD1-1*01 F 3 8 8 17 8.8.17 [2.16.38.11] CAKDIWAREWNDMAAFQMW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift) cgcccccggaatcacttttcccagctatgtcatgagttgggtccgccaggcccagggaaggggctggagtgggtcgcaagcattagtgccaggggcgacagttcatactacgcagactccgtgaagggccgattcaccatctccagggacaatcccaggaccacattgtatctggaaatgaacagtctgagagtcgaagacacggccacatattattgtgcgaaagatatctgggcgcgagagtggaacgacatggcggcttttcagatgtggggccaggggacacttgtcattgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19784 JY8QFUQ01CQXRE unproductive Homsap IGHV3-11*01 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARRRDYGDYGDGFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtGgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19785 JY8QFUQ01CSDB8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 491 69.27 151/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] VHT#AFW out-of-frame + Low V-REGION identity (69,27% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctgaggacaactttggtgaacacgccatgggatggatccgccagtctccgggggggattcttcagtgggtcgctgcgatcagtggtgacggactgacggcgtttcacgcagacttcgtggagggtcgattcagcatctccagagacaatcccataaacactctttttctgcaaatgaacagcctcagagtcgaagattcgggtgtctattttgtgcacacactgccttctggggccggggatcccgggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19786 JY8QFUQ01CDJAN productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgactatcacatgtactgggtccgccaggCctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19787 JY8QFUQ01B6PJ2 productive Homsap IGHV3-7*01 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - tctggattcacctttgagacttattggttgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagacatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaggaactcactgtttctgcaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19788 JY8QFUQ01ASVTH unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ2*01 F 112 67.92 36/53 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVVWSLWYFDL## out-of-frame + in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgCaggggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctgggggccgtggcaccctagtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19789 JY8QFUQ01DNAQY unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 123 68.42 39/57 nt 8 X X 8.X.X [1.9.X.X] null - No rearrangement found ctccggattcacctttagtagttactggatgcactgggtccagggcttcttccccca +19790 JY8QFUQ01COTDH productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1046 97.29 215/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19791 JY8QFUQ01AJWSY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYFYYFDYW in-frame + cctctggattcacctttagccactatgccgtgacctgggtccgccaggctccagggaagggtctggagtgggtctcaactattagtggtagtgatggtagcacgtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagaagtatcactatggttcggggacttacttctactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +19792 JY8QFUQ01DAHIV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 720 81.57 177/217 nt 81.11 176/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDQYGSPSDFDNW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'GGA' (3 nucleotides at position 83 to 85 in the user submitted sequence), (do not cause frameshift); ctcagggttcgtttttgagaaatacgccatgagttgggtccgccaggctcccggaaaggggctggagtgggtctcggctattGGAggtgttgatgatgttggcacatactacgcagcctccgtgaagggtcggttcaccatatccagagacgattccagggagattctctatctacaaatgagtaacctgagagtcgacgatacggccgtctattactgtgcgaaagatcaatatgggagcccatccgactttgacaactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19793 JY8QFUQ01C2LQE No results +19794 JY8QFUQ01B112M productive (see comment) Homsap IGHV3-30*01 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [1.17.38.11] CVKNDLSWGTIEHYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcacgttcaacatttatgGgtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19795 JY8QFUQ01CEI8V productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19796 JY8QFUQ01ACMBD productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggGggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19797 JY8QFUQ01C7TDI productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaAaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19798 JY8QFUQ01AYYP6 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-14*01 ORF 3 8 8 19 8.8.19 [1.16.38.11] CARIIPYDPRTDYYYYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) cctctggattcagcttcagtaattatatcatgacttgggtccgccaggccccaggaaggggctggagtgggtctcatctattagtggaagtagtagtaacatattctacgcagactcaatgaagggtcgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaataatcccgtatgacccgaggaccgactattattactatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +19799 JY8QFUQ01BYPSH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacatactGggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19800 JY8QFUQ01DLCKG No results +19801 JY8QFUQ01CDKKA productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); gcctctggatcacctttggttattgatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtnttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19802 JY8QFUQ01BGWV8 No results +19803 JY8QFUQ01C0M54 unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 1 10 7 X 10.7.X [1.17.38.11] CARRWARQRLVM##YFDYW out-of-frame + stop codons tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatgggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactc +19804 JY8QFUQ01C2GP3 No results +19805 JY8QFUQ01BSGCZ No results +19806 JY8QFUQ01B4YC4 productive Homsap IGHV3-30*01 F 869 88.99 194/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYHFDYW in-frame + cctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19807 JY8QFUQ01B41ZK No results +19808 JY8QFUQ01DGIH1 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARDCDSGECNFDYW in-frame - stop codons ctgattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19809 JY8QFUQ01A2MDY No results +19810 JY8QFUQ01AH7FL unproductive Homsap IGHV1-2*02 F 795 85.98 184/214 nt 85.51 183/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [0.17.38.11] CARDWGGTYAPLDN## out-of-frame + in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); tggatacaTttttcaccggctactatatacattgggtgcgacaggccgctggacaagggcttgagtggatgggatacatcgacccttacagaggtgacacaaggtttgcagagaaatttcagggcagggtcaccttgaccagagacacgtccatcagtacagcctacatggaaatgaccggcctgacgtctgaggacacggccatcttttactgtgcgagagattggggtggcacgtacgcaccgcttgacaactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19811 JY8QFUQ01AE2X1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +19812 JY8QFUQ01AC1Q0 productive Homsap IGHV3-7*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-25*01 F 1 8 8 10 8.8.10 [1.17.38.11] CTKLYRSYYEYW in-frame + cctctggattcagttttagtgactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaatatgaatcaagatggaagtgagaaaaactatgtggactctgtgaagggtcgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatgtattattgtacgaaattgtatcggagctactacgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc +19813 JY8QFUQ01B0RU8 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt +19814 JY8QFUQ01AD9KX unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 919 91.32 200/219 nt 90.41 198/219 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [2.17.38.11] CAKDMGSGRYLEALDHW# out-of-frame - in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); gggtctgacctcatatttactaaatatggcGttccactgggtccgccaggctccaggcaaggggctggagtgggTtggcacttatttggtttgatggaagtaataaatattatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatggacagcctgagagccgaggacacggctgtgtatttctgtgcgaaggatatgggttcgggaagatacttagaagctcttgaccactgggggccccgggaatccaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19815 JY8QFUQ01C1SS7 unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F (see comment) 319 64.25 115/179 nt 8 8 X 8.8.X [1.17.25.X] null - No rearrangement found Low V-REGION identity (64,25% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcttcttcagcagttttggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggcagtcacatcatatgatggaggtaataaattttatggagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19816 JY8QFUQ01DHU43 unproductive Homsap IGHV3-9*01 F (see comment) 755 83.72 180/215 nt 82.79 178/215 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.16.38.11] CGRIAKPGLGALDL## out-of-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 30 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) cgttggattcacttttaatggaacaggcagcagtggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctgggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19817 JY8QFUQ01ALMRY productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F (see comment) 69 60.42 29/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 67 of V-REGION: 'G' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift); cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattaGtgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactgggggccagggaacccctggtcaccgtctcctcagccctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +19818 JY8QFUQ01A8G4A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19819 JY8QFUQ01AELU5 productive Homsap IGHV4-61*02 F 791 99.38 160/161 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-8*01 F 2 X 7 15 X.7.15 [X.8.38.11] CARGYCSNAVCYQIMNW in-frame - ggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagccaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggccgtgtattactgtgcgagaggatattgttctaatgctgtatgctatcaaatcatgaactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19820 JY8QFUQ01CG5WF unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 994 95.83 207/216 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19821 JY8QFUQ01AE75W unproductive (see comment) Homsap IGHV3-48*02 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD2-15*01 F 1 8 8 20 8.8.20 [1.17.38.11] CARPAGGG*PFFPLLLRFWTSG in-frame - stop codons Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 104 of V-REGION: 'T' (1 nucleotides at position 214 to 214 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattacTtgtgcgagacccgcggggggagggtgacccttttttccactactactccggttttggacgtctgggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19822 JY8QFUQ01B3IG6 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaAaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19823 JY8QFUQ01COSA2 No results +19824 JY8QFUQ01A8NCY productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 788 84.4 184/218 nt 83.94 183/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 8 13 8.8.13 [1.17.38.11] CVRGVRDGTGIIDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cccatggattcctcttcagtggccactggatgcactgggtccgccaagctccagacaaggGggctggcgtgggtctcacgtcttaacccggacgggagttttacgaactatccggactccatgaggggccgattcgccatctccagagacaacgccaagaacacagtgtatctgcaaattaacaatctgagacccgatgacacggccgtctattactgcgtaagaggcgtaagagacggaactggaatcatcgactactggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19825 JY8QFUQ01A9POG productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1041 99.53 210/211 nt 97.63 206/211 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.16.38.11] CASANYDYVWGSYRYDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'GA' (2 nucleotides at position 152 to 153 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 31 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 42 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift) ctctggtggctccatcagtagttactactgagctggatccgcagcccccagggaagggactggagtgattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagGAacccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19826 JY8QFUQ01AE4GX productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 899 89.29 200/224 nt 88.84 199/224 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 2 8 10 12 8.10.12 [1.17.38.11] CTITVRPDDYHDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggagtcactttcactaacgtgtggatgagttgggtccggcaggctccagggaaggGggccggagtgggttggccgtattaaaagggagactgagggggggacaatagactacgctgcacccgtgacagcaagattcaccatgtcaaaagatgattcaaaaaacacactatatctgcaaatgaacaacctgaaaatggaggacacagccgtgtattactgtaccataacagtccgaccggatgattaccatgactactggggccagggaaccctggtgaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19827 JY8QFUQ01DGRL0 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 367 67.61 119/176 nt 8 8 X 8.8.X [1.17.24.X] null - No rearrangement found stop codons Low V-REGION identity (67,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19828 JY8QFUQ01CIPSL productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccagGgggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19829 JY8QFUQ01CRQ1F productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame - ctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattattgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19830 JY8QFUQ01BOUUI productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 853 90.73 186/205 nt 89.76 184/205 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.16.38.11] CARHPKSNVEGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 9 nucleotides (from position 14 in the user submitted sequence), (do not cause frameshift)in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) tctctggtgactctcacttctggagctggatccggcagcccccagggaagggcccggantggattgttatgtctataacagtgggaccaccaactacaacccctccctcaggagtcgagtcaccatttctatcgacacgtccaagaagcagatctccctgaagttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +19831 JY8QFUQ01BS2G8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19832 JY8QFUQ01APP4N unproductive Homsap IGHV3-9*01 F 845 88.37 190/215 nt 87.91 189/215 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [0.17.38.11] CARTYGDHDGMDV## out-of-frame - in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift); ctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatcCtttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +19833 JY8QFUQ01AO51H productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARLPNTIDSW in-frame + Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) ttctggatatagttttgccacctactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatgggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccgggtcaccatttcagccgacaagtccctcagtatcgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagactgcctaacactattgactcctggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19834 JY8QFUQ01AUF55 No results +19835 JY8QFUQ01BTU1O productive (see comment) Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 749 82.27 181/220 nt 81.36 179/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARVWVAGSRDENFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); tctcgggtggttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctAggagtggCtttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgacctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19836 JY8QFUQ01AWCEG unproductive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARERGNSYGEIDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggcccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19837 JY8QFUQ01B8Z3T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD2-15*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKRLRGTVVVVDATPSPSTTG in-frame + cctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaaagattacgggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +19838 JY8QFUQ01CYJO3 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - stop codons in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); ctctgattcagcttcagtacctaGtaacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19839 JY8QFUQ01CR76J productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 785 84.16 186/221 nt 83.71 185/221 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFESW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); tttccggtgactccatcaccagtactaattattactggggctgggtccgccagtccccagggaagggtctggagtggattggaagtgtctattatCggggggacccagtacctcaacccgtctctccacaatcgagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtcttttggagtgataattgttaactactttgagtcctggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19840 JY8QFUQ01BO89E productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 8 13 8.8.13 [1.17.38.11] CATYGRFSFSPLDYW in-frame + gtctggattcgacttcagtagttatggcttccattgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctccccttgactactggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagagcttcttccccca +19841 JY8QFUQ01DR4DC productive (see comment) Homsap IGHV3-69-1*01 P 912 92.06 197/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 7 13 8.7.13 [2.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion however the closest V is a pseudogene in CDR1-IMGT at codon 27 of V-REGION: 'A' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 30 of V-REGION: 'AT' (2 nucleotides at position 18 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 66 of V-REGION: 'G' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 3 nucleotides (from position 80 in the user submitted sequence), (do not cause frameshift) agtctctggAattcaccATtcaggtgactacagcatgaactgGggtccgccaggctccagggcaggggctggagtgggtctcatatagtcgcggaagaaccacatGactacgcagactctgtgcagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgcctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19842 JY8QFUQ01AYO67 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtatcgtggaactc +19843 JY8QFUQ01BQNDH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); ctctacattcgcctttagcaactGatgccatgagctgggtccgccaggctccGagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19844 JY8QFUQ01CBA31 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19845 JY8QFUQ01CLR05 unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ1*01 F (see comment) 107 67.31 35/52 nt Homsap IGHD4-23*01 ORF 1 8 8 18 8.8.18 [2.16.38.11] CARVGGNRGVRWYVGT*LLG in-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 32 in the user submitted sequence), (cause frameshift) gtgtctggattcagtttcagtagctttggcagcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatgatctggtatgatggaactaataaatattatgcagactccgtgaagggccgattcaccatctcgagagacaattccaagaacacactgtttctgctcatggacagcctgacagccgacgacacggctgtctattactgtgcgagagtcggggggaaccgaggagttcgctggtatgttggaacttgactactgggggccagggggaccctggtcaccgtctccgcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +19846 JY8QFUQ01BSVHI No results +19847 JY8QFUQ01DU91L productive (see comment) Homsap IGHV3-7*01 F 951 92.73 204/220 nt 92.27 203/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [2.17.38.11] CATDDSNGWDEVADYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); agcctctggattcaccttGcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacggatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19848 JY8QFUQ01AYDD7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD2-21*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARRSGRDGGWFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggattcacctttgtcgactatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtcgcagatattaatggaagaggtgctgccgcacactacgcagactccgtgacgggccgcttcaccctctccaaagacggttccaagaatacgatgtatctgcaaatgaacaccctgagagacgacgacacggccatatattactgtgcgagacgaagtgggcgtgatgggggctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19849 JY8QFUQ01C0UPE unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 901 90.41 198/219 nt 89.04 195/219 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [2.17.38.11] CSKDTFGREDY## out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'GG' (2 nucleotides at position 56 to 57 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); gcctctggattctccgtcagtaAgttactggatgcactgggtccgccaggctccaGGgggaaggggctggGagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19850 JY8QFUQ01BF2P2 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame + tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +19851 JY8QFUQ01CMI13 productive (see comment) Homsap IGHV3-48*03 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARESWWSGFYGWYDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcataGcattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19852 JY8QFUQ01COL8L unproductive Homsap IGHV3-7*03 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-11*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CARDRYSSDSSYYMP#NWLDPW out-of-frame + cctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +19853 JY8QFUQ01CAGS9 No results +19854 JY8QFUQ01CZ8WX productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19855 JY8QFUQ01BDIEE productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*04 F 993 96.26 206/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-15*01 F 2 8 7 21 8.7.21 [1.17.38.11] CARRIQGHCRGGSCSRNNWFDPW in-frame + ctatggtgggtccttcagtggttactactggagttggatccgccagcccccagggaaggggctggagtggattggggaaatcaatcatagtggaagcaccaactacaactcgtccctcaagagtcgagccaccatctcagtagacacgtccaagaagcagttgtccctgaacgtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacggattcaaggacattgtaggggtggtagttgctccaggaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +19856 JY8QFUQ01BDPKN unproductive Homsap IGHV3-33*03 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 X 8.7.X [1.17.38.11] CARDGEQWLVWTL#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctcccagccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19857 JY8QFUQ01ARIMM productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1070 97.77 219/224 nt 97.32 218/224 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.37.11] CTRGSSRGGRYDENYYELDFW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 79 of V-REGION: 1 nucleotides (from position 148 in the user submitted sequence), (cause frameshift) tccggggacagtgtctctaccaacagggctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +19858 JY8QFUQ01CX2HK productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1060 100.0 213/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - tctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgatgtcgtggaactcag +19859 JY8QFUQ01BD58O productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - tctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19860 JY8QFUQ01BQUWB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame + cctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19861 JY8QFUQ01AL9ZT productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 783 84.79 184/217 nt 84.33 183/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [1.17.38.11] CTKTRVVLGITFPFYIYGLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); ctctggattcacgttcgacaactatgccatgagctgggtccgccaggcaccaggaaaggggctggagtgggtctccagtattagtggtaatggagaaattgtacaccacgcagacgccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgTtttttgcaaatgaatggagtgagagacgacgacacggccatttactactgtacgaaaacacgcgttgtgttgggaattacatttccgttctatatctatggtctggacgtctggggccaagggaccacggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +19862 JY8QFUQ01A3U10 unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARVRGYYGGQYFDS## out-of-frame + ctctggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19863 JY8QFUQ01BAZ4Q productive Homsap IGHV1-2*02 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame + tggatatactttcaccgaccattatgtttactggatgcgacaggcccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19864 JY8QFUQ01ANNUC productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt 87.21 191/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.17.37.11] CAGSGRDPYGINVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 171 in the user submitted sequence), (cause frameshift) ggcctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19865 JY8QFUQ01CB1XO productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame - ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19866 JY8QFUQ01BC36T unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 153 53.89 97/180 nt 8 7 X 8.7.X [1.17.26.X] null - No rearrangement found cctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19867 JY8QFUQ01CEAUW No results +19868 JY8QFUQ01A4IHW productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 919 89.47 204/228 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 10 15 8.10.15 [3.17.38.11] CVTGVKASGGAHAMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcagcctctggattcagtttcagagacgcctggatgaattgggtccgccagtctccagggaaggggctggagtgggttggccgtgttaaaaggaaaactgatggtgggacgtcggaatatgctgcattcgtgaaaggcagattcaccatctcaagagatgattcagaaaacacactgtatctgcaaatgaacagcctggaaatcgacgacacagctgtgtatcgttgtgtcacaggagttaaggcttcggggggggctcacgctatggacgtctggggccaagggaccgcggtcatcgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcagcccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19869 JY8QFUQ01BRR78 unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 99 61.9 39/63 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDRELHYQHLDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctgggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19870 JY8QFUQ01B6TA3 productive Homsap IGHV4-4*07 F 872 89.77 193/215 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 7 12 8.7.12 [1.17.38.11] CARFSSYGDTFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctgatgggtccatcggaagttactactggacttggatccggcagcccgccgggaaggcaatggagtggatcgggcgtgtctttagaactgggaacacgaattacaacccctccctcaagagtcgggtcaccatgtcagttgacacgtccaagaatcaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgttttactgtgcgagattctcgtcctacggtgacacctttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19871 JY8QFUQ01C71PP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19872 JY8QFUQ01BQCJG productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.17.38.11] CARGEMTAEYYFDYW in-frame + tctctggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19873 JY8QFUQ01B0TU1 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame - ctctggattcagcttcagtagctacagtatgaactgggtccgccaggctccagggaaggggctggagtggatttcatctattagcaccaccagtagtaccataggctacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagacgaggacacggctgtgtactactgtgccaaagtgggtaacctgtatttctttgaatactggggccggggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19874 JY8QFUQ01BOB1S unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARVMREHYYGAGNYPWGGMEV## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcacctttaacaactatgccatgacctgggtccgccaggctccggggaaggggctggagtgggtctcagctatcagtggcagtggcggtaccacttactacgcagactccgtgcagggccgcttcaccatttccagagacaatcacgaaaacaccctgtatctggaaatgagtagcctgagagccgaggacgcggccgtctattactgtgcgagagtgatgagggaacattattatggagcggggaattatccctgggggggaatggaagtctggggccaggggaccacggtgcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19875 JY8QFUQ01DP79K unknown (see comment) Homsap IGHV1-2*02 F (see comment) 759 83.64 179/214 nt 81.78 175/214 nt 8 8 X 8.8.X [0.17.38.X] null + No rearrangement found Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'TC' (2 nucleotides at position 81 to 82 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 93 of V-REGION: 'C' (1 nucleotides at position 183 to 183 in the user submitted sequence), (cause frameshift); tggatacatcttcaatgacttctacatatattgggtgcgacaggCcccctggacaagggcttgagtggatgGggatgggtTCaacccctaatagtcgtgtcacagactatgcagagaaatttcagggcagggtcaccatgaccggggacccgtcccgcagcacagtccacctgaaactgaccCcgcctgaagtcggacgacacggccgtctattactgcgcgagaggtctctcctcagcatcccccgaccagcccccaaggtcttccccgctgagccctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +19876 JY8QFUQ01AL2ZJ unproductive (see comment) Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKRRVGDTSDWY#YFEYW out-of-frame + stop codons cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19877 JY8QFUQ01ACXLB productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 890 90.7 195/215 nt 89.3 192/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [1.17.38.11] CTRELRVAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); cctctggattcaccgtcagtaccaagGttcatgagctgggtccgccaggctccagggaaGggggctggagtgggtctcagtaaCtttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +19878 JY8QFUQ01C3MZ0 No results +19879 JY8QFUQ01C4X7F No results +19880 JY8QFUQ01C3ZLL productive (see comment) Homsap IGHV3-11*01 F 955 93.15 204/219 nt 91.32 200/219 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 8 8 19 8.8.19 [2.17.38.11] CVRRGLGDTVMVPFRITSTTG in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 80 of V-REGION: 'G' (1 nucleotides at position 148 to 148 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 208 to 208 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaagGgggctggagtggatttcatacattagtggGgagtgcgactaccatatcctacgcagactttgcgaagggccgattcaccatctccaGgggacaacgccaagaactcggtgtatctgcaaatgaacagcctgagagccgaggacacgGgccacgtattattgtgtgaggcggggtctgggggatacagttatggttccgtttcgtattacttcgactactgggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatggggaaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +19881 JY8QFUQ01BD4LD No results +19882 JY8QFUQ01AJ3EX productive Homsap IGHV3-48*01 F 1004 95.87 209/218 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARVGATLSFDVW in-frame + cctctggattcaccctcagtagctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtattagtagtggtaccatatactatgcagactctgtgaagggccgattcaccatctccagggacaatgccgagaactcactgtatctgcaaatgagcagcctgagagccgacgacacggctgtgtattactgtgcgagagtgggagcgacgctttcttttgatgtctggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +19883 JY8QFUQ01DM135 No results +19884 JY8QFUQ01DWQ32 No results +19885 JY8QFUQ01B14S8 productive (see comment) Homsap IGHV3-33*05 F (see comment) 742 82.87 179/216 nt 82.41 178/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.16.38.11] CVKGRGYNDYGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaagggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19886 JY8QFUQ01C12ZF No results +19887 JY8QFUQ01AMWC7 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 876 89.77 193/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccntgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19888 JY8QFUQ01BDD3D No results +19889 JY8QFUQ01BGI3K productive (see comment) Homsap IGHV4-61*02 F 807 85.0 187/220 nt 84.55 186/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 10 7 18 10.7.18 [1.17.38.11] CARENYYGSGSYGRAWFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 128 to 128 in the user submitted sequence), (cause frameshift); ctctggaggctccatcagcagtggaagctacttctggacctggatccggcagcccgccgggaaggatctggagtggattaggcgcttctacagtagtgacagtgtcgactacaacccctccctcaggGggtcgagccaccatttcagcggacacgtccaagagccagttctcccttaatctgaagtctgcgaccgccgcagacacggccgtttattactgcgcgagagagaattactacggttcggggagttatgggcgggcctggtttgactactggggcccgggaatccaggtcaccgtctctgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19890 JY8QFUQ01C0H80 productive Homsap IGHV3-48*01 F 1085 100.0 218/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19891 JY8QFUQ01C1K22 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 794 84.62 187/221 nt 84.16 186/221 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFESW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tttccggtgactccatcaccagtactaattattactggggctgggtccgccagTcccccagggaagggtctggagtggattggaagtgtctattatcgggggacccagtacctcaacccgtctctccacaatcgagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtcttttggagtgataattgttaactactttgagtcctggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +19892 JY8QFUQ01BY231 productive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 929 91.4 202/221 nt 90.95 201/221 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 10 7 18 10.7.18 [1.17.38.11] CARSAYCGADCYSADYLQHW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtaggggttactactggaactggatccgccagttcccagggaagggcctggagtggattgggaacatcttttacagtgGggggcacctacgacaacccgtccctcaggagtcgaatttctatatcattagacacgtctaagaaccaattctccctgaagttgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcacgcacccagccagatgggaacgtgtcatcgcctgctggtccagggcttcttccc +19893 JY8QFUQ01DB79A productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19894 JY8QFUQ01DQP7X productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19895 JY8QFUQ01BU39A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctggagttcagcctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19896 JY8QFUQ01BD1DU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19897 JY8QFUQ01COU9I productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 707 80.73 176/218 nt 78.9 172/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [2.17.38.11] CARLDGHFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'C' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); tagtctctgggttcGaccatcagtCacgtactccatgggCctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgGcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19898 JY8QFUQ01CPKDU productive Homsap IGHV3-30*15 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVRGAYHFDSSSYIGAGW in-frame - cctctggattcaccttcagtagttatgctatgcactgggtccgccaggctccaggcaaggggccagagtgggtggcagtcatagcatatgatagaagtagtcagtattatgcagactccgtgaggggccgattcaccatctccagagacgattccgagaagacactgtatctacagatgagcagcctgagagctgaggacacggctacatattactgtgtgagaggggcgtatcactttgacagtagtagttacattggcgcgggctggggccagggaaccccggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19899 JY8QFUQ01ADJKJ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame - cgtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19900 JY8QFUQ01DWHEJ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 928 91.78 201/219 nt 91.32 200/219 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [2.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); gcctctacattcGccctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19901 JY8QFUQ01C8H4R unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 417 82.11 101/123 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found Low V-REGION identity (82,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgtttctacttacaccattttctacgcagagtctgtta +19902 JY8QFUQ01DQ5MO unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CTREVGATDY## out-of-frame - cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19903 JY8QFUQ01BNMQ9 No results +19904 JY8QFUQ01DACAZ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt 87.1 189/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.37.11] CIMDLVGRADYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 83 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) cctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaagGgggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgcgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19905 JY8QFUQ01BICKU unknown (see comment) Homsap IGHV2-5*01 F 1062 93.03 227/244 nt 92.62 226/244 nt 10 7 X 10.7.X [9.17.38.X] null + No rearrangement found in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 187 to 187 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgctccttctctgggttctcgctcagtaccgatggggtggctgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcactcaattattggaataatgacaagcgctacaggtcttctctgaagggcaggctcaccatcaccaaggacacctccaaaaaTccaggtggtccttacaatgaccaacatggaccctgcggacacagccacatattattgtgcacgcagaccatgttactctgatacccggtggttaccactgtttctttgactcctgggggccccggggaacccctggtcaccggtctccacagcatcccccggaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +19906 JY8QFUQ01CBE2T unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 862 89.67 191/213 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 97 66.0 33/50 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [X.17.38.11] CARRDVGLHAFDL## out-of-frame + tggatccaatttaactacgactggatcggctgggtgcgccagatgcccggtaaaggcctggagtggatgggaatggtctatgttggtgactctgatgctagatacagcccgtcctcccaaggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgcttttgatctgtggggcccaggggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcctgggcttcttccccca +19907 JY8QFUQ01BIJC2 productive Homsap IGHV3-13*01 F 957 94.39 202/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaacttcttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctccctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaactc +19908 JY8QFUQ01CW4B2 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 914 91.28 199/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 9 7 9 9.7.9 [1.17.38.11] CARLKRKFDSW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'ACTG' (4 nucleotides at position 34 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'CA' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 108 to 108 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 3 nucleotides (from position 30 in the user submitted sequence), (do not cause frameshift) tgtctggtggctccatcagcagaagtactttctACTGggggctggatccgccagcccccCAgggaagggggctggcgttgattgggagtatctataacaatgggggcCacctactacaacccgtccctcaagagtcgagtcaccatatcagtggacacgtccaagaatcagttctccctgaagctgagttctgtgaccgccgcagacacggctatatattactgtgcgagactgaagaggaaatttgactcttggagccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagccacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19909 JY8QFUQ01ALQL0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19910 JY8QFUQ01DFGZK unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [0.17.38.11] CARLPFIVVVTGAFFG##FDYW out-of-frame + stop codons in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); tggatacatctttaccaattactggctcggctgggtgcgccagatgcccggCaaaaggcctggagtggatggggatcatctttcctgctgactctgatgcccgatacagcccgtccttccaaggccaggtcaccatctcaatcgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacgccgccatatattactgtgcgagactcccctttattgtggtggtgactggtgcgttttttgggacactttgactattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +19911 JY8QFUQ01A6P66 unproductive Homsap IGHV3-7*01 F 978 94.09 207/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CAISSGFLLDG#YW out-of-frame - aggctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtgggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19912 JY8QFUQ01DII08 productive (see comment) Homsap IGHV3-11*01 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-9*01 F 2 8 8 24 8.8.24 [1.17.37.11] CARDCHVDILTGYYRGSPPSCGLGVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 96 of V-REGION: 1 nucleotides (from position 193 in the user submitted sequence), (cause frameshift) ctctggattcaagctcggtgactactatatgaattggatccgccaggctccagggaaggggctggagtgggtttcatatattagtcttggtggtagccccacatattatgcagactctgtgaagggccgattcaccatctccagggacaacgccaacaattcactatatctacagatgagtgccctgagagcgaggacacggccgtatattattgtgcgagagattgtcatgtcgatattttgaccggttattatcggggttcgcctccttcttgcggtctgggcgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19913 JY8QFUQ01DEK7J unproductive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 156 to 156 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccAaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaaacggcgaccttgactactgggggccaggggaacccctggtcacccgtctcctccagcatcccccgaccagcccccaaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19914 JY8QFUQ01B8CGD productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 990 95.39 207/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctacaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19915 JY8QFUQ01BZYQ8 unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [0.17.38.11] CARXGGMVRGLIITLQILGT#YYCVMDVW out-of-frame + in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacatgttcaccaactactatatacactgggtgcggcaggCcccctggacaagggcttgagtggatgggaataatcaaccctagtggtggtagtacaaagaacacacagaagttccagggcagagtcaccatgagcagggacacgtccacgaacacagtctacatggagttgagcggtctgagaactgaggacacggccgtgtattactgtgcgaganccgggggcatggttcggggacttattataaccctacaaatcctgggtactcctactactgcgttatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19916 JY8QFUQ01CL5PF productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcatctttgatgattttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +19917 JY8QFUQ01CCCJ0 unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F (see comment) 650 76.92 170/221 nt 76.47 169/221 nt 10 7 X 10.7.X [2.16.38.X] null - No rearrangement found Low V-REGION identity (76,92% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gtctctggtggctccatcagcagtagtagttactactgggcctggatccgccagccccagggaaggggctggagtgccttgggagcatcttttatagtgggcgcaccaaccaggacccgtccctcaagagtcgagtcaccttatccgttgacacttccaagaaccagttctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +19918 JY8QFUQ01DBQJG unproductive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcaaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19919 JY8QFUQ01AUJTS No results +19920 JY8QFUQ01A3WJG No results +19921 JY8QFUQ01ABDK7 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDRFPMVREKIAP#EYW out-of-frame + stop codons ctctggattcacctttaggaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcgcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaggagcacgctgcatatgcaaatgaacagcctgagagccgaggacacggccgcatattactgtgcgaaagaccgttttcctatggttcgggaaaaaatcgccccctgagtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacacggcccctgggctgcctggtcaaggactacttcccccgaacccggtgacggtgtcgtggaactcag +19922 JY8QFUQ01BQ15A No results +19923 JY8QFUQ01ANDRJ unproductive (see comment) Homsap IGHV3-30*01 F 1085 100.0 218/218 nt 99.54 217/218 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD4-17*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDAQC*ALLLLRYG#VW out-of-frame + stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctatgctatgcactgggtccgccaggctccaggcaaggGggctagagtgggtggcagttatatcatatgatggaagtaataaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgagagatgcccaatgttaggcactactactactacggtatggatgtctggggccaagggaccacggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +19924 JY8QFUQ01BM0GO productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 830 88.21 187/212 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD6-19*01 F 1 8 7 20 8.7.20 [X.17.38.11] CVRDGRRTYNSGWYSLAAFDIW in-frame - tgtctgccatcagcagtggtaactggtggagctgggtccgccagcccccagggaaggggctggaatggattggagaaatctcttatagtgggaccaccaagtacaaccggtccctcaagagtcgagtcaccatatcactagacacgtccaaaaaccatttctccctgcagctgacttctgtgaccgccgcggacacggctgtctattattgtgtgagagatggtcgccggacctataacagtggctggtattcgttagctgcttttgatatctggggccaggggacagtggtcaccgtctcttccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19925 JY8QFUQ01CWSU1 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgCtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcacccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19926 JY8QFUQ01C4JPO unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CATRNKSGN*YA##DYW out-of-frame + stop codons in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); cctctggactcaacattggcaactatgacatgacctgggtccgccaggctcctgggaaggggctggagtgggtctcaagtattggaactactgagggtagctcatattatgcagactccgtgaagggccggttcaccatctccagagacaactcccagactacgctgTtttttggagatgagcagcctgagagacgaggacacggccgtatattactgtgcgacaaggaataaaagtgggaattagtacgcctgttgactactggggccagggaaccctagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +19927 JY8QFUQ01AVWT3 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1001 95.02 210/221 nt 94.12 208/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD1-26*01 F 2 10 7 X 10.7.X [1.17.38.11] CARLVG##WVDPW out-of-frame + in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctctggtgactccatcaccagtagtaattactactgGgggctggatccgccagcCccccagggaaggggctggagtggattgggagtgtctattatactgggagtacccactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaaggtgacttctgtgaccgccgcagacacggctgtgtataactgtgcgagactggtgggggcactgggtcgacccctggggccagggaaccctggtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca +19928 JY8QFUQ01BXAYL productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 876 89.77 193/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccntgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19929 JY8QFUQ01DCHN6 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - in FR2-IMGT at codon 47 of V-REGION: 'T' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccaTgggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19930 JY8QFUQ01CLUTY unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19931 JY8QFUQ01C8YVG unproductive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*05 F 975 95.33 204/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [0.17.38.11] CAGDRGSGFWGGSYRPN#YGLDVW out-of-frame + tggatacaccttcaccaactactatcttcactgggtgcgacaggcccccggacaagggcttgagtggatgggacggatcaacccaaacagtggtggcacaacctatgcacagaagtttcagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgagcaggctgagatctgacgacacggccgtctattactgtgcgggagatcgggggtccggtttttggggtggttcatataggccaaatctacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +19932 JY8QFUQ01C2ZLH unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1085 100.0 218/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-16*02 F 2 8 8 X 8.8.X [1.17.38.11] CARARATTRGELSSN#YGMDVW out-of-frame + cgtctggattcaccttcagtagctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagcccgcgccaccacaaggggggagttatcgtcaaatctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +19933 JY8QFUQ01DCXWU No results +19934 JY8QFUQ01CL3D8 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 856 88.13 193/219 nt 87.67 192/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.16.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) gcctccgggattcacctttagtagtttctggatgcactgggtccgcaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19935 JY8QFUQ01BDZXU productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 999 95.85 208/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 2 7 8 13 7.8.13 [1.17.38.11] CARGPAGGSGAYEYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) cctctggattcaagtttgagattccggcatgagctgggtccgccaagctccaGgggaaggggctggagtgggtctctggtattaattggaatggGtggtaagacaggttatgGgagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatttgcaaatgaacagtctgagagccgaggacacggccttgtattactgtgcgagaggccccgccgggggatctggcgcatatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctgacagcacccccccaaagatgggaacgtggtccgtcgcatggccctggtccagggcttcttcccccag +19936 JY8QFUQ01DRNLO productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19937 JY8QFUQ01BET09 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame + cctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggccaggggaccacggtcaccatctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +19938 JY8QFUQ01CBOUS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt 84.4 184/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 75 of V-REGION: 'AG' (2 nucleotides at position 130 to 131 in the user submitted sequence), (cause frameshift); gctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccAGggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19939 JY8QFUQ01BW5V9 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 903 91.59 196/214 nt 91.12 195/214 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-13*01 F 3 8 7 12 8.7.12 [1.17.37.11] CARGVGQQLPPLDW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 188 in the user submitted sequence), (cause frameshift) tctctcgtggctccatcactccttcctactggagctggatccggcagcccccagggaagggactggagtggattggatatatctatgacagtgggagtaccaagtacaacccctccctcaagagccgagtctccatatcaatagactcgtccaagaaccagttctccctggagctgttctctgtgacgctgcggacacggccatatattactgtgcgagaggggtggggcagcaactgccccccttagactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +19940 JY8QFUQ01AI0OF unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 514 92.44 110/119 nt 8 8 X 8.8.X [1.17.5.X] null - No rearrangement found cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagaccca +19941 JY8QFUQ01BL9YR No results +19942 JY8QFUQ01B6PRR productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19943 JY8QFUQ01ASGTL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt 84.79 184/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDPGNYWGYYYDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); gtctggattcacctttagtgattatgccttgagctgggtccgccagactcccgggaaGggggctggagtggatctcagAaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgagagatccgggaaattattggggatactattatgactcttggggcctgggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19944 JY8QFUQ01B8JIN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19945 JY8QFUQ01AT3U1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19946 JY8QFUQ01ABNG3 productive Homsap IGHV4-39*02 F 839 86.88 192/221 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19947 JY8QFUQ01C29JI productive Homsap IGHV4-4*07 F (see comment) 683 80.0 172/215 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD2-8*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARECTNEAGGPRHLDSW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01C29JI ; 8 AA in Homsap_IGHV4-4*07), and low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggccccatcaatagtagtgactactattggacttggatccggcagcccgccgggaggggactggaatgggtcgggcgtgtcttcatgaatggccttaccgactacaatccatccttcggcagccgtctcaccatgtccattgacatgtcgaagaaccaattctccctgaagttgacctctgtgaccggcgctgacacggccctttattactgtgcgagagaatgtactaatgaggctggcggaccgagacacctggactcctggggccacggaactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +19948 JY8QFUQ01DUSSF productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 777 85.05 182/214 nt 83.64 179/214 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARNRGYTPASGLASW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'A' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 86 of V-REGION: 'CG' (2 nucleotides at position 160 to 161 in the user submitted sequence), (cause frameshift); tggatacattttcacccagtcctatatAgaatggggtgcggcaggcccctgggcaagggcctgagtggatgggaataatcagtccaagggttggcaccGacaacctacgcacacaagttccagggcagaatcaccgtgaccatggacacgtccacgacgCGacagtctacatggagctgagcagcctgacatctgacgacacggccatttactattgtgcgagaaataggggttacaccccagcgtctgggcttgcctcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagccaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19949 JY8QFUQ01C13DG No results +19950 JY8QFUQ01C9V29 productive (see comment) Homsap IGHV4-39*03 F 893 89.14 197/221 nt 88.24 195/221 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [2.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'TGG' (3 nucleotides at position 74 to 76 in the user submitted sequence), (do not cause frameshift); gtctccggtggctccatcaacagtagaaAattattattggggctggatccgccanccccccagggaagggtttTGGgagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19951 JY8QFUQ01ABAX4 productive (see comment) Homsap IGHV3-7*01 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggGggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19952 JY8QFUQ01B9HOL productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +19953 JY8QFUQ01BGX18 No results +19954 JY8QFUQ01BGZ0J productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt 94.06 206/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDCDSGECNFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19955 JY8QFUQ01BPJLB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYFYYFDYW in-frame + cctctggattcacctttagccactatgccgtgacctgggtccgccaggctccagggaagggtctggagtgggtctcaactattagtggtagtgatggtagcacgtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagaagtatcactatggttcggggacttacttctactactttgactactggggccagggaaccctggtcaccgtctcctcagccatccccgcacccagccccaaggttccttcccgctgacgcctccgaagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +19956 JY8QFUQ01AL5BM unproductive (see comment) Homsap IGHV3-9*01 F 922 92.13 199/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKRRVGDTSDWY#YFEYW out-of-frame + stop codons tctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +19957 JY8QFUQ01DKUU6 productive (see comment) Homsap IGHV3-9*01 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggGggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc +19958 JY8QFUQ01BTIG6 productive Homsap IGHV3-66*02 F 953 93.95 202/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame + cctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19959 JY8QFUQ01B8SWU productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARSLGHDSGDKRGFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); tctctgttgactccatcCagtaatttctattggagctggatccggcagcccccagggaagcgactggagtggattggatatatcgattacagtgggaccaccaagtacaacccctccctcatgagtcgactcaccatatcactagacacgtccaagaagcagttgtccctgaaggtgacctctgtgagtgctgcggacacggccgtctattactgtgcgagatccctcggccatgactccggtgacaaacggggctttgactactggggccagggaatcccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19960 JY8QFUQ01ATWYV unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 904 91.2 197/216 nt 90.28 195/216 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.16.38.11] CVRAGFGELSGFDC## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 50 of V-REGION: 'GCTGGGA' (7 nucleotides at position 62 to 68 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 75 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggGCTGGGAgtggggtcagtctgggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctgggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc +19961 JY8QFUQ01AUEO7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 828 87.1 189/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGFSAWGQDAFDIW in-frame + ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19962 JY8QFUQ01AOUX0 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +19963 JY8QFUQ01B77AO unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 80 51.13 68/133 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons tctggattcacctttaacctctatgtcatgcactggttccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19964 JY8QFUQ01ANXIN unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 181 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRGQGNGAG#DYW out-of-frame - cctctggattcaccttcagtaactactggatgcactgggtccgccaagctccagggaaggggctgctctgggtctcagtcattaatagtgacggcagtgaaattcactacgcggactccgtgaggggccgattcaccatctcccgagacaacgccaagaacacgctgtatttgcaaatggacaatctcagaggcgacgacacggctctatattattgtgtaagaggacaagggaatggagcgggattgactactggggtcagggaaccctggtcaccgtntcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19965 JY8QFUQ01CNRF9 unproductive (see comment) Homsap IGHV3-7*01 F 733 95.06 154/162 nt 94.44 153/162 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD2-15*01 F 3 8 0 X 8.0.X [1.17.27.11] CAKGGW*RRP*LL# out-of-frame + stop codons in CDR2-IMGT, from codon 56 of V-REGION: 55 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggctggtaacggcgaccttgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggctcagggcttcttccccca +19966 JY8QFUQ01B1Y8J productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactatatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc +19967 JY8QFUQ01AL8DZ No results +19968 JY8QFUQ01CHQY5 productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*05 F 893 89.59 198/221 nt 88.69 196/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 10 7 15 10.7.15 [1.17.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcggtagtacCtaactactggagctggattcggcagcccccagggaagggactggaattcattgggtatatctattccagtgggaggaccaactacaaccCcctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19969 JY8QFUQ01BW5CI productive (see comment) Homsap IGHV3-11*01 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19970 JY8QFUQ01CARI1 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19971 JY8QFUQ01AMH9V productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [1.17.38.11] CACYFDSNGFFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); ttctggatacgtctttccctcctactggatcgcctgggtgcgccagatgcccggTaaaaggcctggagtggctgggaaccatctatcccggcgactctgacaccacatacagcccgtcattccaaggccaggtcaccatgtcagtcgacacgtccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacagcgccatttactattgtgcgtgttattttgatagtaatggtttctttgactactggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +19972 JY8QFUQ01CZC9J unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 926 90.62 203/224 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD3-22*01 F 3 8 10 X 8.10.X [1.17.38.11] CATDRPYYKNRCWPTLVLLRYGRFG# out-of-frame + tctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaatcgctgctggccgactctggtattactacggtatggacgttttgggggcccaaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19973 JY8QFUQ01CF54U productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 88.69 196/221 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-19*01 F 2 10 7 16 10.7.16 [1.17.38.11] CTNDHSMAVSAKHAFDVW in-frame + tctctggtgcctccatgagcagtagtgcatactactggggctgggtccgccagacccccgggaaggggccggagtggattgggagtgtctactatggtgggagcacctactacaacccgtccctcaagagtcgggcctccatttctgtcgacacgtccaggaacgagttctccctgaggctgaactctgtgaccgccacagacacggctatgtattactgcacgaacgaccattcaatggcagtctctgctaagcatgcttttgatgtttggggtccagggacaatggtcaccgtctcttcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19974 JY8QFUQ01DLSCT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19975 JY8QFUQ01AWCAC unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 946 92.69 203/219 nt Homsap IGHJ3*02 F 191 86.0 43/50 nt Homsap IGHD1-20*01 F 3 8 8 X 8.8.X [2.17.38.11] CAARIDSVITG#AFDIW out-of-frame - ggctctggatacagtttcaccaactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctggtgactctgatacccggtacaacccgtccttccaaggccaggtcaccttctccgtcgacaagtccatcaacaccgcctacctgcagtgggacagcctgaagacctcggacaccgccaagtattactgtgcggcgagaattgatagtgtcattactggaatgctttcgatatatggggccaagggacgatggtcaccgtcgnttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19976 JY8QFUQ01CPM2Q productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1044 98.16 213/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKAGTYYYDSSGYYFLDYW in-frame + ctctggattcatcttcagtagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagccggcacgtattactatgatagtagtggttattacttccttgactactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaaccc +19977 JY8QFUQ01CCTPT No results +19978 JY8QFUQ01A79QG No results +19979 JY8QFUQ01CD0CK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccgagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19980 JY8QFUQ01BRREL productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 962 94.42 203/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame + tctctggtggctccatcgatagttactactggacctggatccggcagcccccagagaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccccc +19981 JY8QFUQ01BZQWU productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19982 JY8QFUQ01BHR4C productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggGggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +19983 JY8QFUQ01AQIF3 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19984 JY8QFUQ01B7TY8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 769 84.26 182/216 nt 83.33 180/216 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 7 8 13 7.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'GGC' (3 nucleotides at position 102 to 104 in the user submitted sequence), (do not cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctctggattcattttagaaattttgccatgagttggctccgccaggcaccagggaaggggctggaatgggtctcgactatcagcagcactagtggtgacacGGCatattactcagactccgtgaggggccgcttttccatctccagagacaactccaagagcactctgttcttgcagatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19985 JY8QFUQ01CA830 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattctaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +19986 JY8QFUQ01AHPUP No results +19987 JY8QFUQ01C2013 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt +19988 JY8QFUQ01CH27C productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 590 89.73 131/146 nt 89.04 130/146 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 6 17 8.6.17 [1.17.16.11] CAKKYHYGSGSYLYSFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 71 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) ctctgggttcacctttgcccactttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtggtgatgattccacaaatggacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactcctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatcgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +19989 JY8QFUQ01C8W78 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 796 84.0 189/225 nt 82.22 185/225 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 13 8.10.13 [2.17.38.11] CATDSPTGYYAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'GC' (2 nucleotides at position 164 to 165 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 92 of V-REGION: 'A' (1 nucleotides at position 192 to 192 in the user submitted sequence), (cause frameshift); gcctctgggttcGattttcagtgatgcctggatgagttgggtccgccaggcGtccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcGCaaaaaacatggtgtatctgcaattgaAaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +19990 JY8QFUQ01CJ7SX No results +19991 JY8QFUQ01A6LXJ productive Homsap IGHV3-23*05 F (see comment) 447 83.08 108/130 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 X 5 16 X.5.16 [X.X.38.11] CVRYDYSRLHRSNYFGPW in-frame - Low V-REGION identity (83,08% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcatcagttatgactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19992 JY8QFUQ01CAABS unproductive (see comment) Homsap IGHV3-48*01 F 896 90.37 197/218 nt Homsap IGHJ1*01 F (see comment) 116 69.23 36/52 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CARESTWVIYS*LL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattcagtttcagtgactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagttctagtagtaccctatattatgcagactctgtgaagggccgattcaccgtctccagagacaatgacaagagttctctgtatctgcaaatgaccggcctgagagccgaagacacggcgacttattactgtgcgagagagtcgacgtgggtaatttactcctgactcctgggggcccggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccgctgagcctctgcagcacccagcagcatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +19993 JY8QFUQ01B8T2M unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 715 91.18 155/170 nt 90.59 154/170 nt 8 7 X 8.7.X [2.17.22.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01B8T2M ; 8 AA in Homsap_IGHV3-11*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); gcctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggGggccgattcaccatgtccagggacaacgccaagaactcactgtatct +19994 JY8QFUQ01B55MN No results +19995 JY8QFUQ01DF5ST productive (see comment) Homsap IGHV3-7*01 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); gcctctacattcacgtttagtcggtattggatgagctggtaccgccaggctccagggaagggcctggGagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19996 JY8QFUQ01AIZSY unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 854 88.84 191/215 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CARVDFYGSSKYK##FDPW out-of-frame - tctctggtaactccatcacagattattactggagctggctccggcagtctccagggaagggactggagtggattggaaatgtcttttacagtgggagagccaactacaacccctccctcaagagtcgagtcaccatatcagtagccacgtccaggaaccagttctccctgaagctcaggtctgtgaccactgcggacacggccatatattattgtgcgagagttgatttctatggttcgagtaaatataagggggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19997 JY8QFUQ01BIHI6 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + cctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +19998 JY8QFUQ01AC7XN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-17*01 F 2 8 8 14 8.8.14 [1.17.38.11] CASVDWVFDGDYGGYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); cctctaaattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcacaggtattagtggtggtggtgAaaaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagaggcgaggacacggccgtttattactgtgcgagcgtagattgggtgttcgacggtgactatggcggctactggggtcagggaaccccggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +19999 JY8QFUQ01A0JN8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20000 JY8QFUQ01CXQLB productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGNYYYFGMDVW in-frame + tctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccatctactactgtgcgagacaaactgggaattattattacttcggtatggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +20001 JY8QFUQ01CHHSM productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.16.38.11] CGRPPLYSSGWQHPFNFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) gttctggatacaactttaccgactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgatggggatcatctatcccggtgactctgatatcacatatagtccgtccttccaaggccaggtcaccatctcagtcgacaagtccatcagcaccgcctacctgcagtggaacagcctgaaggcctcggacaccgccatgtattattgtgggagacccccactatatagcagtggctggcaacatccttttaatttctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20002 JY8QFUQ01CRT5B No results +20003 JY8QFUQ01BZZTH unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 975 95.33 204/214 nt 94.86 203/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [0.17.38.11] CASAPLIVVDTTF#YW out-of-frame - in FR2-IMGT at codon 47 of V-REGION: 'GA' (2 nucleotides at position 52 to 53 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagttactatatgcactgggtccgacaggcccctggGAccaagggcttgagtggatgggaatgatcaaccctagtggcggaagcacaatctacgcacagaacttccagggcagagttgccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgctagcgcccctctgatagtagtggatactactttcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagccaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca +20004 JY8QFUQ01BP5Z0 unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 803 85.07 188/221 nt 84.16 186/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - stop codons in FR2-IMGT at codon 39 of V-REGION: 'TGG' (3 nucleotides at position 38 to 40 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'GC' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtactcattactaattTGGgggctggatccggcagGCcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20005 JY8QFUQ01CKP5J No results +20006 JY8QFUQ01AD65R productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20007 JY8QFUQ01AYKFE unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGG## out-of-frame + ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtggggggggaccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20008 JY8QFUQ01CXSD6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20009 JY8QFUQ01CCYXO unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CATSRGSANWYPFDH## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactgggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20010 JY8QFUQ01AXDTZ No results +20011 JY8QFUQ01B46Q3 No results +20012 JY8QFUQ01A4YYJ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1085 100.0 218/218 nt 99.54 217/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); cctctggattcaccGtttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20013 JY8QFUQ01AKQ9T productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 852 87.73 193/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - aggttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaataaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20014 JY8QFUQ01CAK37 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1031 97.25 212/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDLTGYSSERNYW in-frame + cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaacttactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20015 JY8QFUQ01A33ZY productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 883 89.5 196/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [2.17.38.11] CSKDTFGREDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'TA' (2 nucleotides at position 144 to 145 in the user submitted sequence), (cause frameshift); gcctctggattctccgtcagtaattactggatgcactgggtccgccaggctccagGgggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttTAacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggttttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +20016 JY8QFUQ01DBRIC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame - ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20017 JY8QFUQ01CFQCN productive (see comment) Homsap IGHV3-11*01 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20018 JY8QFUQ01BU7GA unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 503 93.04 107/115 nt 8 8 X 8.8.X [1.17.4.X] null + No rearrangement found ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagac +20019 JY8QFUQ01B8VRB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcacctttagaagctatgccatgagctGgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20020 JY8QFUQ01AY22T productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggGggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +20021 JY8QFUQ01ARXJY No results +20022 JY8QFUQ01AHS6H productive (see comment) Homsap IGHV3-7*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaAaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +20023 JY8QFUQ01AOBY5 No results +20024 JY8QFUQ01A0N8H productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1013 94.27 214/227 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGNYYDSGGLDYW in-frame - tctccggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcgaataactatcaagccagacgcatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtatattactgtgcaagagggggtaattactatgatagtggtggtcttgactattggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20025 JY8QFUQ01CXAUC productive (see comment) Homsap IGHV3-30*15 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARNELPWDTREYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctccggattcacctttagtaaatattccatgaactgggtccgccaggctccaggcaAaggggctcgagtgggtggcacttatatcatacgatggaagtagaaaaatctacgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20026 JY8QFUQ01CEKVC unknown (see comment) Homsap IGHV4-61*02 F 956 92.76 205/221 nt 92.31 204/221 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT at codon 88 of V-REGION: 'A' (1 nucleotides at position 173 to 173 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagtggtagttactactggagctggacccggcagcccgccgggaggggcctggagtggattgggcgtgtccataacagtggtagttccaattacaagccctccctcacgagtcgagtcaccatattagtagacacgtccaagaatcagttctcAcctgaagctgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagagaagcgcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20027 JY8QFUQ01BBG2O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [1.17.38.11] CSIRMLGTTGVDYW in-frame + cctctggattcacctttagcagctatgccatggactgggtccgccaggctccagggaaggggctggagtgggtctcagatattactggtggtggtggtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagccgaggatacggccatatattactgttcaataaggatgctgggaactactggtgtggactactggggccagggaaccctggtcaccgtctcctcagcatccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20028 JY8QFUQ01A6XZ7 productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'T' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccTttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +20029 JY8QFUQ01BYHHU productive Homsap IGHV3-9*01 F (see comment) 770 83.94 183/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgatcagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20030 JY8QFUQ01AVTMY productive (see comment) Homsap IGHV3-7*01 F 896 92.34 193/209 nt 91.87 192/209 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 6 8 14 6.8.14 [X.17.38.11] CVRGRDGVNFGEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); tcatctttagtagacattggatggcctgggtccgccaggctccagGggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20031 JY8QFUQ01AM4BN productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtagatattggatgcactGgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +20032 JY8QFUQ01CCI5X productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20033 JY8QFUQ01C3FR9 productive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 920 90.95 201/221 nt 90.5 200/221 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 10 7 18 10.7.18 [1.17.38.11] CARSAYCGADCYSADYLQHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); tctctggtggctccgtGcagcagtaggggttactactggaactggatccgccagttcccagggaagggcctggagtggattgggaacatcttttacagtgggggcacctacgacaacccgtccctcaggagtcgaatttctatatcattagacacgtctaagaaccaattctccctgaagttgacctctatgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20034 JY8QFUQ01CAN4N No results +20035 JY8QFUQ01C5UH4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKSLYQWLVHA#NWFDPW out-of-frame - gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20036 JY8QFUQ01AL2AF productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +20037 JY8QFUQ01BG2F7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARGEFYYETSGRRGFDYW in-frame + ctctggattcaccttcactacctcctggatgcactgggtccgccaagctccagggaaggggctaatgtgggtcgcacgtattaataaggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaccacactgtacttggaaatggacagtctgagagtcgaggacacggctatgtattattgtgcaagaggggaattttactatgaaactagtggtcgaaggggttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20038 JY8QFUQ01B51BL productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20039 JY8QFUQ01DNL8F productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 869 88.99 194/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + cctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct +20040 JY8QFUQ01BX3XY unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 135 55.56 75/135 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20041 JY8QFUQ01DRBO0 unproductive (see comment) Homsap IGHV3-43*01 F 1009 95.89 210/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKR*DWVL#YYFDHW out-of-frame + stop codons in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); gcctcaggattcacatttgctgaatataccatgcactgggtccgtcaagttccGggggaagggtccggagtgggtctctcttattagttGgggatggtggcagcacatactatgcagactctgtgaagggccgattcaccatctccagagacaacagcaaggactccCctgtatctgcaaatgaacagtctgagaactgaggacaccgccttgtattactgtgcaaaaagataggattgggtccttgtactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagccctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc +20042 JY8QFUQ01BBWVB productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.37.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 177 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccaggGgaaggggctggagtgggtttcataGccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgagactcat +20043 JY8QFUQ01AOR3J productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt 87.16 190/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDGGSYNRMDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 82 of V-REGION: 'G' (1 nucleotides at position 153 to 153 in the user submitted sequence), (cause frameshift); cgtctgggttcagtttcattgactatggcatacactgggtccgccaggctccaggcaAaggggctggagtggatggcaattatatggtatgatgggaaaaataaatattatgaagagtccgtgaagaaccgattcaccgtctccagagacaaGttccaagaacacggtgtatttggaagtgaatagtctgagagtcgacgacacggctgtgtattactgtgcgagagacggtgggagctacaacaggatggacctttggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20044 JY8QFUQ01AN9O8 productive (see comment) Homsap IGHV4-61*02 F 816 85.91 189/220 nt 85.45 188/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 10 7 18 10.7.18 [1.17.37.11] CAREDYYGSGSYGRAWFDSW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 119 in the user submitted sequence), (cause frameshift) tctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtgggggtgtcgactacaaccctccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagaggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttccttccccca +20045 JY8QFUQ01DCIL6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSGPSGYARYESMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggtgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20046 JY8QFUQ01BEUH6 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 840 88.32 189/214 nt 86.92 186/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [2.16.38.11] CAKNNNDFGDYDWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'T' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 2 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) tctcctggtggTctccatcagtagttcctactggagttgatccgcagcccccagggaagggcctggagtggattggttatgtctattacTactgggggcaccgactccaacccctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20047 JY8QFUQ01A9OIU unknown (see comment) Homsap IGHV3-11*03 F, or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F 84 51.52 68/132 nt 8 10 X 8.10.X [2.17.9.X] null - No rearrangement found stop codons gcctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20048 JY8QFUQ01ARK4E unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 833 87.16 190/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARGDGYNFGGLDY## out-of-frame + cctctggattcaacttcataggttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactccgtgaggggccgatccatcatttccagagacgattctaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20049 JY8QFUQ01BSC8A unproductive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 843 87.27 192/220 nt 86.36 190/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 X 10.7.X [1.17.38.11] CATGVAGP#YFDSW out-of-frame + in FR3-IMGT at codon 67 of V-REGION: 'G' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 103 of V-REGION: 'G' (1 nucleotides at position 218 to 218 in the user submitted sequence), (cause frameshift); ctctggtggctccgtcagcagtggtaattactactggaactggatccgccaacccccagggaagggactggagtggattggatatatctactatgctggggccaccaacGtcgcccccctccctcaagaaccgagtcaccataacgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccgtatattaGctgtgcgacgggcgtggctggaccccctactttgactcctggggccagggaaatctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20050 JY8QFUQ01BGMA3 productive (see comment) Homsap IGHV3-48*03 F 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) tctggattcaccttcagttcttatgccatgaactgggtccgcctggtccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20051 JY8QFUQ01C12H2 productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARELGGSGTCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); tggatacaccttcaccaggcactatatgcactgggtgcgacaggcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggGggcagagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20052 JY8QFUQ01CYR71 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20053 JY8QFUQ01ABVQH productive (see comment) Homsap IGHV3-74*03 F (see comment) 842 87.61 191/218 nt 87.16 190/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] YVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); cctctggattcacGtttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattatgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20054 JY8QFUQ01B8303 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F (see comment) 87 64.58 31/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 92 of V-REGION: 'A' (1 nucleotides at position 178 to 178 in the user submitted sequence), (cause frameshift); tctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctacaaatgAaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20055 JY8QFUQ01BMNAR productive (see comment) Homsap IGHV3-21*04 F 952 92.34 205/222 nt 91.44 203/222 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [3.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gcagcctctggatttaccttcagtctctatagaatGgaactgggtccgccaggctccaCgggaagggactggagtgggtctcatccattactagtaccagtagttacatttattatgcagacccagtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtatctccagatgaacagcctgagagccgaggacacggccgtatattactgtgtgaggcgggtgtggggatacagctatggttccgtctcgtactattttgagtactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +20056 JY8QFUQ01DQWN3 No results +20057 JY8QFUQ01A10RN productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +20058 JY8QFUQ01A9GYP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt 85.25 185/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); gtctggattcacatttagaagctattccatgaattgggtccgGccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgCcacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaGgggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20059 JY8QFUQ01ALNYY productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20060 JY8QFUQ01COZPR productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20061 JY8QFUQ01AEDWR No results +20062 JY8QFUQ01CVCQ8 productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20063 JY8QFUQ01CF8T3 No results +20064 JY8QFUQ01B634H No results +20065 JY8QFUQ01CDTUO No results +20066 JY8QFUQ01A2B9H unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 935 91.07 204/224 nt 89.73 201/224 nt Homsap IGHJ6*04 F 126 66.67 42/63 nt Homsap IGHD3-22*01 F 2 8 10 X 8.10.X [1.17.38.11] CATDRPYYKKRCWPTLVLLRYGRF## out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'T' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 132 to 132 in the user submitted sequence), (cause frameshift); tctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaagGgggctggagtgggttgcccgtgttaaaaacTaagactgacgatggggcaacagactacgctgcacccgtgaAaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaaacgctgctggccgactctggtattactacggtatggacgttttggggcccaaagggaccacggtcaccgtctcctcagcctccaccaaggggccccatcggtcttcccccctggcaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtgggaactcag +20067 JY8QFUQ01C83BF productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggggggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20068 JY8QFUQ01CO79G No results +20069 JY8QFUQ01A0C2Y productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20070 JY8QFUQ01CTPBR productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20071 JY8QFUQ01CQF9N productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtcccagggcttcttccccc +20072 JY8QFUQ01A6TG7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20073 JY8QFUQ01CAKSD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcccaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20074 JY8QFUQ01C03YM unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +20075 JY8QFUQ01BZUJK No results +20076 JY8QFUQ01AN8X4 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt 91.59 196/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 97 of V-REGION: 'C' (1 nucleotides at position 192 to 192 in the user submitted sequence), (cause frameshift); tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaAaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccCccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +20077 JY8QFUQ01CTGRK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-3*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARGGLEPRRLLG in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagccccgtagattattgggggccaggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctcccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20078 JY8QFUQ01AQAT6 unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1009 95.89 210/219 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [2.17.38.11] CVRGGLRWRPRTLLRP#YGLDVW out-of-frame - gcctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagagggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +20079 JY8QFUQ01B449A productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20080 JY8QFUQ01B1XKB No results +20081 JY8QFUQ01C42IH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggGggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20082 JY8QFUQ01CE84V productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20083 JY8QFUQ01DFZV1 No results +20084 JY8QFUQ01C6K8W unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 497 84.17 117/139 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (84,17% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc +20085 JY8QFUQ01B2MMF productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20086 JY8QFUQ01A1201 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 995 95.41 208/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame + cctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +20087 JY8QFUQ01CF7E5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 779 84.4 184/218 nt 83.49 182/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARDGEWEMLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctccggattcaccttcagtaggtattggatgtattgggtccgccaagctccaggCaaagggggctgtgtgggtctcacgcattGaaaaagtgtgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacatatttttgtgcaagagacggggagtgggagatgcttgaccactggggccagggagccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20088 JY8QFUQ01CPZUJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +20089 JY8QFUQ01C9W74 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 834 86.82 191/220 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [2.17.38.11] CAKSPLSVAGTRQKLVR#PG out-of-frame - ggctctgacttgcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaaactggttcgacccctgggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20090 JY8QFUQ01DN49K productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20091 JY8QFUQ01CD8ZK productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 815 86.24 188/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame + cctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacaacaccccccaagtggtcgtcgcatgcctggtccagggcttcttcccccag +20092 JY8QFUQ01CJ631 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CTKDSDMVGATYEDW in-frame + gctctggattcaactttaatacctatggcatgaattgggtccgccaggctccagggaagggactggagtgggtctcaagtatcactggtagcggtggtgatttgtactatgcagactccgcgaagggccggttcaccatctccagagacaattccaagaacaccctgtatctgcaaatagacagcctgagagccggggacacggccacatattattgtacgaaagacagtgatatggtgggagctacttatgaggactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20093 JY8QFUQ01BBVC2 productive Homsap IGHV1-69*08 F (see comment) 768 84.58 181/214 nt Homsap IGHJ3*02 F 124 72.0 36/50 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [0.17.38.11] CARDCDTSGGRCPEAFKMW in-frame + Low V-REGION identity (84,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ggggggcacattcagcacacatattatcagctgggtgcgacaggcccctggacaaggacttgagtggatgggaagggtcatcccgataattaacacagcaaactacgcacacaattttcagggaagagtcacgatgaccgcggaaatgtccacgagcacggcctacatggaactgtccggcctaagatctgacgacacggccgtctactattgtgcgagagactgtgacactagcggcggtaggtgccccgaggcgttcaaaatgtggggccaagggacaatggtcatcgtcgtcttcagcctccacaagggcccatcggtcttccccctggcagccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaact +20094 JY8QFUQ01B0LXB unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20095 JY8QFUQ01DACHY unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1055 97.74 216/221 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [2.17.38.11] CARPYCGGDCHNRGAFDI## out-of-frame - cagcgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctgggggccaagggacaatggtcaccgtctcttcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20096 JY8QFUQ01CE9AZ productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 7 14 8.7.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 83 in the user submitted sequence), (cause frameshift) cgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttattggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20097 JY8QFUQ01CGIDS No results +20098 JY8QFUQ01AF664 productive Homsap IGHV4-4*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [1.17.38.11] CARGKDYYDTTGSLEDGFDIW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctctggtggctccataagaagttactattggagttggatacggcactccgccgggaagggactggagtggatcgggcgcatatatgacagtggtagtacaaactacaatccctccctcaagagtcgagtcagcatgtcagtggacacgtccaagaaccaggtctccctgaagttgatctctgtgaccgccgcggacacggccatgtattattgtgcgagagggaaggattactatgatacaactggctccctcgaggatggttttgatatttggggccaagggacgatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20099 JY8QFUQ01BDUBV productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20100 JY8QFUQ01CCTJR productive Homsap IGHV1-3*01 F 822 87.38 187/214 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [0.17.38.11] CVRGRSPPGDWFDPW in-frame + tggatacaccttcactaattatgctctgcaatgggtgcgccgggcccccggacaaacttttgagtggctgggatggatcaactctgccaatggcaacacaaaatattctcagaagtttcagggcagagtcgccattaccagggacacatccgcgaggacaacttacatggaattgagcagtctgacatctgaagacacggcgacatattattgtgtgagaggaagaagtccgcccggcgactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20101 JY8QFUQ01AZJVY unproductive (see comment) Homsap IGHV3-7*01 F 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [2.16.38.11] CATSPLR*LLGRT#YW out-of-frame - stop codons in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) gcctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctcccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +20102 JY8QFUQ01BW5DS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 833 87.16 190/218 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD3-16*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASLNTHAGPGAERSAFDVW in-frame + cctctggattcatcttcagtaactatagaatgaactgggtccgtcaggctccagggaaggggctcgagtgggtctcgtccatcaccagttccagtagttacatctactatgcagactcggtgacgggccgattcaccatctccagagacaactccaaggggtcactctatctgcacatgaacgaccttagggccgaagacacggctgtctattactgtgcgagcctaaacacgcacgcgggaccgggagccgagaggtctgcttttgatgtctggggccgagggacaagggtcaccgtctcctcaccatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +20103 JY8QFUQ01CNER6 No results +20104 JY8QFUQ01A1VSO No results +20105 JY8QFUQ01CPOAR No results +20106 JY8QFUQ01B4K3S productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20107 JY8QFUQ01CZANE productive Homsap IGHV4-61*02 F 951 92.73 204/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame + ctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20108 JY8QFUQ01AKFDN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 163 92.11 35/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found cctctggattcacctttaccaactatggcatgagctgg +20109 JY8QFUQ01AY0TJ No results +20110 JY8QFUQ01DE64X unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [2.17.38.11] CARDLRGLDYGIR#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); gcctccggattcagtttcagtacttataacatgaattGgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaaggggtctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20111 JY8QFUQ01CX3E4 No results +20112 JY8QFUQ01AWT1P productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1014 95.91 211/220 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRSEYSSSNWFDPW in-frame - agcctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20113 JY8QFUQ01CPA88 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); ctctacattcgcctttagcaactTatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20114 JY8QFUQ01ASUJY unproductive Homsap IGHV3-38*01 ORF (see comment) 111 59.09 52/88 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt X X X X.X.X [X.X.29.11] TVRNWKIAVGMKTP (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION Low V-REGION score, and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctgaattaacgtttgacaattccaagaacatgttgtatttgcaaatgaacaacctgcgagggcgaggacacgggccgtttattactgtgcgaaactggaaaatagcagtgggaatgaagactcctggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20115 JY8QFUQ01DKB30 No results +20116 JY8QFUQ01DBO11 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 937 92.24 202/219 nt 91.32 200/219 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD3-3*01 F 3 8 8 15 8.8.15 [2.17.38.11] CAKQTIFDYYYYGLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); gcctctggattcatgtttagtagctttcccatggcctgggtccgccaggctccagggaaGggggctggagtgggtctctagtattagtggtaGggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20117 JY8QFUQ01CA0P8 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 928 91.78 201/219 nt 91.32 200/219 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [2.17.38.11] CAREVSDAFEMW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cctctgggattcacctttgatgattttggcatgagttgggtccgccaagttccagggaaggGggctggagtgggtcgctggtatcagttggaatggaggcaaaacaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcattgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20118 JY8QFUQ01BI513 No results +20119 JY8QFUQ01DFEGX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 995 95.41 208/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +20120 JY8QFUQ01AKVHK productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 995 95.41 208/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPAGGSGAYEYW in-frame + cctctggattcaagtttgatgattccggcatgagctgggtccgccaagctccagggaaggggctggagtgggtctctggtattaattggaatggtggtaagacaagttatggagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatttgcaaatgaacagtctgagagccgaggacacggccttgtattactgtgcgagaggccccgccgggggatctggcgcatatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +20121 JY8QFUQ01CL52F productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20122 JY8QFUQ01DGMBS productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 984 95.79 205/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CASAPSDSSGYYFSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagttactatatgcactgggtccgacaggCcccctggacaagggcttgagtggatgggaatgatcaaccctagtggcggaagcacaatctacgcacagaacttccagggcagagttgccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgctagcgccccctctgatagtagtggatactacttttcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20123 JY8QFUQ01CRLLH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactca +20124 JY8QFUQ01CM5UC unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 977 94.5 206/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 142 76.0 38/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDFTYAFDL## out-of-frame + cgtctggattcacgttcagtagttatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatcatctggtatgatggaagtaatcaatattatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacggtgtatctacaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgaaagattttacgtacgcctttgatctctgggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20125 JY8QFUQ01A5E5J productive (see comment) Homsap IGHV3-7*01 F 982 94.52 207/219 nt 94.06 206/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [2.16.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 43 in the user submitted sequence), (cause frameshift) gacctctggattcacctttagtaaccattggatgaactgggtcgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20126 JY8QFUQ01ABNDS unproductive (see comment) Homsap IGHV3-7*01 F 949 93.52 202/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPLGVGG#FDNW out-of-frame - stop codons in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'T' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); tctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggGggctggagtgggtggccaacataAaaccaagatggaggtgacaTgggcctatgtggGactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttggggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20127 JY8QFUQ01CCO0W productive Homsap IGHV3-30*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 1 8 8 9 8.8.9 [1.17.38.11] CAREGGGFDYW in-frame - ctctggattcagtttcagtagctatgcaatgcattgggtccgccaggctccaggcaaggggctagagtgggtgacagttatatcagctgatgcaactaccagtcactacgcagactccgtgaagggccgattcacccactccagagacaattccaagaacacgctgtctctgcaaatggacagcctgagacctgaagacacggctgtatattactgtgcgagagaggggggcggatttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20128 JY8QFUQ01DNK5V unproductive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 937 92.24 202/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKKPT*IGGPMI#YFDSW out-of-frame + stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 171 to 171 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcaggaactatgctatgcactgggtccgccaggctcctggcaaGggggctagaatgggtggcttTttatatcatatgatggaagtagtcaatactacgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacacttTtatctggaaatgaacagtctggacgctgaagacacggctgtgtattactgtgcgaaaaaaccgacctgaattgggggaccaatgatatttattttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20129 JY8QFUQ01DJ82G unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 131 83.78 31/37 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found cttctggattctcctttagcaactatgccctggcctg +20130 JY8QFUQ01ALVZH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcanttcccccgaaccggtgacggtgtgcgtggaactca +20131 JY8QFUQ01CAXMD productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 931 92.59 200/216 nt 91.67 198/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 40 of V-REGION: 'T' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); tccggattcagtttcagtacttataacatgaaTttgggtccgccaggctccagggaaggGggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20132 JY8QFUQ01CHRYW unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKETTRQWLVPI#ALDVW out-of-frame + stop codons ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20133 JY8QFUQ01BD8LY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame + ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20134 JY8QFUQ01DBP8Z No results +20135 JY8QFUQ01AFC3M productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20136 JY8QFUQ01CJCW2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20137 JY8QFUQ01A313A productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20138 JY8QFUQ01B9OYE productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 995 93.39 212/227 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 179 77.05 47/61 nt Homsap IGHD3-9*01 F 2 10 9 12 10.9.12 [1.17.38.11] CVRDYDTLTLLDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctccgggggacagtgtttctaggaacaatgctgcttggaactggatcaggcagtccccgtcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtatctgtgaaaggtcgaataaccatcaacccggacacatccaagagccagttctccttgcagttgaagtctgtgactcccgaggacacggctgtgtactactgtgtaagagactacgatactttgaccctcttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20139 JY8QFUQ01B2EBO No results +20140 JY8QFUQ01CN5AJ productive Homsap IGHV3-30*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 1 8 8 9 8.8.9 [1.17.38.11] CAREGGGFDYW in-frame + ctctggattcagtttcagtagctatgcaatgcattgggtccgccaggctccaggcaaggggctagagtgggtgacagttatatcagctgatgcaactaccagtcactacgcagactccgtgaagggccgattcacccactccagagacaattccaagaacacgctgtctctgcaaatggacagcctgagacctgaagacacggctgtatattactgtgcgagagaggggggcggatttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20141 JY8QFUQ01BVY45 productive Homsap IGHV3-48*04 F 923 91.74 200/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame - cctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20142 JY8QFUQ01AVQX3 productive (see comment) Homsap IGHV3-7*01 F 964 93.61 205/219 nt 92.69 203/219 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [2.17.38.11] CATSPSDFDRRWGYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); gcctctggatttagctttagaaccttttggatgagctgggtccgccaggctccagggagGggggctggagtgggtggccaacataaAagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20143 JY8QFUQ01DAUGI unproductive (see comment) Homsap IGHV4-61*02 F 988 94.14 209/222 nt 92.79 206/222 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 1 10 7 X 10.7.X [2.17.38.11] CATVAXRG#AFDIW out-of-frame + stop codons in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 98 of V-REGION: 'A' (1 nucleotides at position 205 to 205 in the user submitted sequence), (cause frameshift); gtctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatgGgggcgtatctataccagtgggatcaccaactacaaCcccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagAacacggccgtttattactgtgcgacagtggcgcnccgggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaaggggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20144 JY8QFUQ01DGK9U productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD2-21*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDPQQILAEVNWFDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 87 of V-REGION: 'T' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift); cctctggattcacctttcgcagctacgccatgagttgggtccgccaggctccaggaagggggctggagtgggtctcctcaatcagtggcagtggtgataaaacaaaatatgcagactccgtgaagggccgattcaccatctccagagacaatgcgaggaacactTttttatctgcatatgaacagcctcagagccgcggacacgggcgtctactattgtgcgaaagatcctcagcagatactggcagaagtaaactggttcgacccctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccagg +20145 JY8QFUQ01AEQTJ unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 923 91.74 200/218 nt 91.28 199/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in FR3-IMGT at codon 69 of V-REGION: 'GT' (2 nucleotides at position 115 to 116 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtcgttatagcatgaactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggcagtagcacaagctacggggGTactccgtgaagggccgattcaccgtctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgcgagtcgacgacacggctctatattattgtgcaagaggccgtatagtagcagttggggatgtcaggctggttcgacccttgggggccagggaacccctggtctccgtctctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggctt +20146 JY8QFUQ01AHX2Q productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20147 JY8QFUQ01BZW00 productive Homsap IGHV1-69*06 F, or Homsap IGHV1-69*14 F 840 88.32 189/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-7*01 F 1 8 8 9 8.8.9 [0.17.38.11] CVIKTSYYDYW in-frame - tggaggcaccttcaacaccattacttttagttgggtgcgacaggcccctggacaagggctcgagtggatggggggggtcatccctctctttagtagaacaaattacgcagaaaacttccagggcagagtcacaattaccgcggacaagtccacgaccacagcctacatggagttgagcagcctgagatttgaggacacggccatgtattactgtgtgatcaaaactagttattatgactactggggcctgggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20148 JY8QFUQ01CEUBT unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-49*01 F or Homsap IGHV3-49*03 F or Homsap IGHV3-49*04 F or Homsap IGHV3-49*05 F 131 83.78 31/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcgtctttggcgactatgcgatgagctgg +20149 JY8QFUQ01BG853 productive (see comment) Homsap IGHV3-7*03 F 811 85.84 188/219 nt 85.39 187/219 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [2.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctccggattcaAtttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +20150 JY8QFUQ01BL2G8 unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 692 78.57 176/224 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 10 X 8.10.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (78,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcactgtcaataacgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgatggcgggacagcagactacgctccatttgtggacgacagattcaccatttcaacagatgattcaaaaaacacgttgtatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20151 JY8QFUQ01BOJ7D No results +20152 JY8QFUQ01DREVE productive Homsap IGHV3-7*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20153 JY8QFUQ01ACESU No results +20154 JY8QFUQ01BC7DQ unproductive (see comment) Homsap IGHV4-61*02 F (see comment) 920 90.95 201/221 nt Homsap IGHJ6*01 F 229 84.13 53/63 nt 10 7 18 10.7.18 [1.17.38.11] IVRRGKWGDKPPFYYGMDVW (see Functionality comment) in-frame + stop codons, IMGT/JunctionAnalysis gives no results for this JUNCTION Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctgattgattgtncgacgagggaagtggggggacaaaccgcccttctactacggtatggacgtctgggggccaaggaccacggtcaccgtntcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20155 JY8QFUQ01ADOO5 productive (see comment) Homsap IGHV4-4*07 F (see comment) 688 80.09 173/216 nt 79.63 172/216 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD2-8*01 F 2 10 7 16 10.7.16 [2.17.38.11] CARECTNEAGGPRHLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gtctctggtggccCccatcaatagtagtgactactattggacttggatccggcagcccgccgggaggggactggaatgggtcgggcgtgtcttcatgaatggccttaccgactacaatccatccttcggcagccgtctcaccatgtccattgacatgtcgaagaaccaattctccctgaagttgacctctgtgaccggcgctgacacggccctttattactgtgcgagagaatgtactaatgaggctggcggaccgagacacctggactcctggggccacggaactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20156 JY8QFUQ01B21HW productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 881 90.23 194/215 nt 88.84 191/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); tctctggcgactccatcagtggtcactactggagctggatcaggcagCcccccagggaagggactgcagtggattgggttacatctatccagtgggagcaccaactacaaCcccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctCccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcacccctcctccaagagcacctctggggggccacagcggcccctggggctgccctgggtcaagggactacttcccccgaaccggtgacggtgtcgtggaact +20157 JY8QFUQ01AECRJ productive Homsap IGHV3-9*01 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame + cctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20158 JY8QFUQ01AM8RY unproductive Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 98.61 213/216 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.16.38.11] CASRLRSSGGY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctatagcatgaactgggtccGgccaggctccagggaagggctggagtgggtttcatGacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20159 JY8QFUQ01AEOIN unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CARLGPGSGTDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctactggagctggatccggcagcCccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20160 JY8QFUQ01BCTIC unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 177 85.42 41/48 nt 8 X X 8.X.X [1.6.X.X] null + No rearrangement found tctctggagtcactttcactaacgtgtggatgagttgggtccggcagg +20161 JY8QFUQ01AU7TR productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 876 89.77 193/215 nt 87.91 189/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'TG' (2 nucleotides at position 62 to 63 in the user submitted sequence), (cause frameshift); cttctgggttcaccgtcagtagcaaGgttcatgagctCgggtccgcCcaggctccagggaaTGgggctgggantgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20162 JY8QFUQ01C416K No results +20163 JY8QFUQ01AOR8Z unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 880 90.61 193/213 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD6-19*01 F 2 8 7 X 8.7.X [1.17.38.11] CARTEYVSGWYIGGFD#PW out-of-frame + tatggtgggtcactcagttcttatttctggagctggatccgccagtccccagagaaaggactggagtggattggggaaatcaatcagagtggaaccaccaactacaacccgtctctcaggagtcgagtcaccatagcaatagacacgtccaagaaccagttctccctgaaggtgacctctgtgtccgccgcggacacggctgtctattactgtgcgaggaccgagtatgtcagtggctggtacatcggggggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctgccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag +20164 JY8QFUQ01B8HJH productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20165 JY8QFUQ01AYVGU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20166 JY8QFUQ01AKEAH No results +20167 JY8QFUQ01CC1DT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame + gcctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgagaacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtccgtcgcatgcctggtccagggcttcttcccccag +20168 JY8QFUQ01AF795 No results +20169 JY8QFUQ01BG2KS productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F (see comment) 791 83.93 188/224 nt Homsap IGHJ4*02 F 165 88.1 37/42 nt Homsap IGHD6-13*01 F 2 8 10 5 8.10.5 [1.17.38.11] CMAGGYW in-frame + Low V-REGION identity (83,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaatttcaatagtgccatgatgggctgggtccgccaggctccaggtaaggggctaaaatgggttggtcttattaagaccaatgcagatggtgggacaacaaattacgctgcacccgtgcaaggcagatttgtcatctcaagagaggattcagtaaataccctttatctgcaaatggacagcctgaaggtcgaagacacagccgtctattactgtatggcaggtggttactggggccagggagccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20170 JY8QFUQ01DEEV3 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt +20171 JY8QFUQ01DMSA6 productive (see comment) Homsap IGHV3-66*02 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD6-13*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARDSPYSSGWSDGFDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 83 of V-REGION: 'T' (1 nucleotides at position 150 to 150 in the user submitted sequence), (cause frameshift); cctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatatcagtggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaatTtcgaagaacacggtgtatcttcagatgaacagtctgagagctgaggacacggctgtgtattactgtgcgagagatagtccatatagcagcggctggtctgatggctttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccaag +20172 JY8QFUQ01A23OB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARFGPLTRPDYWG in-frame + cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccaggggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20173 JY8QFUQ01AWFQT productive Homsap IGHV3-48*01 F 923 91.74 200/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGNYYYFGMDVW in-frame + cctctggattcctcttcagtagctttaacatgaactgggtccgccaggttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccatctactactgtgcgagacaaactgggaattattattacttcggtatggacgtctggggccaagggactacggtcaccgtctcctctgcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20174 JY8QFUQ01B3UOA productive (see comment) Homsap IGHV3-7*01 F 1004 95.87 209/218 nt 95.41 208/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 7 8 11 7.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) gcctctggattcaccttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20175 JY8QFUQ01B8M9T unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20176 JY8QFUQ01AOZL3 No results +20177 JY8QFUQ01ASD8L unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 497 84.17 117/139 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (84,17% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc +20178 JY8QFUQ01DJONI productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame + cgtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaaactca +20179 JY8QFUQ01AU1D0 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.17.37.11] CVRDSDSSGYARYDSMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 100 of V-REGION: 2 nucleotides (from position 206 in the user submitted sequence), (cause frameshift) gcctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20180 JY8QFUQ01CAZ32 No results +20181 JY8QFUQ01DOK1D No results +20182 JY8QFUQ01B7EYY productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); gctctggattcaccttcagttcccactggatgcactgggtccgccAaagctccagggaaggggcttgtgtgggtcgcacgaatcaattctaatggaaaaagtgcaagttatgcggagtccgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagacgaggacacggctgtgtactactgtgccaaagtgggtaacctgtatttctttgaatactggggccggggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20183 JY8QFUQ01C8DDQ productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 675 78.8 171/217 nt 77.42 168/217 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.17.37.11] CAREDIVREGLDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (78,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'AC' (2 nucleotides at position 51 to 52 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 215 in the user submitted sequence), (cause frameshift) tgtctggtggctccatcgccacttatcattggtggaattgggtccgccagACcccccggggaagggactggagtggattgGgggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattatgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccggaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20184 JY8QFUQ01CALA4 productive (see comment) Homsap IGHV4-61*07 F (see comment) 775 84.02 184/219 nt 83.11 182/219 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGHYSFETW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'A' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); gtctggtggctccgtcagcagtggAaaattcctactggacttggatccgccagTccccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggtcattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20185 JY8QFUQ01AM31I unknown (see comment) Homsap IGHV3-74*03 F 126 54.81 74/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20186 JY8QFUQ01A3NO6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.74 200/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 79 to 81 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagGggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgtgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgt +20187 JY8QFUQ01CHW1K productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20188 JY8QFUQ01CFK1J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD2-15*01 F 2 8 8 21 8.8.21 [1.17.38.11] CAKTGGQCSGGNCYLHYYGMDVW in-frame + ctctaaattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcacaggtattagtggtggtggtgaaaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagagcatgttgtatctgcaaatgaacagcctgagagccgaagacacggccgtattttactgtgcgaaaactggcggtcaatgcagtggtggtaactgctatttgcactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +20189 JY8QFUQ01C1CXV productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 921 92.52 198/214 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [0.17.38.11] CSNGYGDFPRRW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20190 JY8QFUQ01DJI9S unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggcccaggggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20191 JY8QFUQ01CGJ0L productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20192 JY8QFUQ01DJX4C productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 998 94.2 211/224 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcgaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20193 JY8QFUQ01AGKNE productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); gcctccggattcacctttagtagttactggatgcactgggtccgccaaactccagGgggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20194 JY8QFUQ01BB204 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt 83.94 183/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [1.17.38.11] CTKTRVVLGITFPFYIYGLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 169 to 169 in the user submitted sequence), (cause frameshift); cctctggattcacgttcgacaactatgccatgagctgggtccgccaggcaccaggaaAaggggctggagtgggtctccagtattagtggtaatggagaaattgtacaccacgcagacgccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgTtttttgcaaatgaatggagtgagagacgacgacacggccatttactactgtacgaaaacacgcgttgtgttgggaattacatttccgttctatatctatggtctggacgtctggggccaagggaccacggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20195 JY8QFUQ01CUAXD productive Homsap IGHV3-72*01 F 899 89.29 200/224 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 10 12 8.10.12 [1.17.38.11] CARDLGNGWGYDYW in-frame - cctctggcttcatcttcagtgaccactatatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagagttgcatctaacacttacgccacagaatacgccgcgtctttcaaaggcagattcgtcatctcaagagacaattcaaggaactcattgtttctccaaatgaacagcctgaaaaccgacgacacggccatgtattattgtgctagagatctgggcaatggctggggctatgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20196 JY8QFUQ01C9P1S unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgcctgagcctcgacagcacccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20197 JY8QFUQ01CPDLP productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 724 81.94 177/216 nt 81.48 176/216 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [2.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'CAG' (3 nucleotides at position 55 to 57 in the user submitted sequence), (do not cause frameshift); gtctcgagtgcctccatgatcagttactattggacctggattcggcagccccccCAGggaaggggactggagtggattgaggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20198 JY8QFUQ01CAUG4 productive (see comment) Homsap IGHV3-7*01 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaaaCgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgg +20199 JY8QFUQ01BBJ2G productive (see comment) Homsap IGHV1-3*01 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacagcttcactaactacaatatccattgggtgcgccaggCcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +20200 JY8QFUQ01A5C4M productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 739 82.19 180/219 nt 81.28 178/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [2.17.38.11] CARYRVGDSLYYGLDGW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'ACT' (3 nucleotides at position 92 to 94 in the user submitted sequence), (do not cause frameshift); gcctctggattcatttttagaaattttgccatgagttggctccgccaggcaccagGggaaggggctggaatgggtctcgactatcagcagcACTagtggtgacacggcatattactcagactccgtgaggggccgcttttccatctccagagacaactccaagagcactctgttcttgcagatgaacagcctgagtgccgaagacacggccatttactactgtgcgagataccgtgtgggtgacagtctctactacggtttggacggctggggccaagggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +20201 JY8QFUQ01B4ZZI unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20202 JY8QFUQ01BVJ0N productive (see comment) Homsap IGHV3-7*01 F 823 87.04 188/216 nt 86.57 187/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKAGRGLIRPNNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift); tctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaAGggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcggggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +20203 JY8QFUQ01BBBFG productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20204 JY8QFUQ01A81PE unproductive Homsap IGHV3-23*03 F (see comment) 809 86.51 186/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD6-25*01 F 3 8 7 X 8.7.X [1.17.38.11] CTRELRMAAARDGVDI## out-of-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01A81PE ; 8 AA in Homsap_IGHV3-23*03) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggattcaccttcatcagttatggcatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatcctgatgggactacacactatggagactccgtgaggggccgattcaccacctccagagacaattctaagaacatcttggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggatggctgcggcgcgtgatggtgttgacatctggggcccaaggcacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +20205 JY8QFUQ01BRWCE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20206 JY8QFUQ01CYW73 productive (see comment) Homsap IGHV4-61*02 F 857 87.78 194/221 nt 86.88 192/221 nt Homsap IGHJ4*03 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARERSASMGAARELDSW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'GGG' (3 nucleotides at position 100 to 102 in the user submitted sequence), (do not cause frameshift); tctctggtggccCccatcggcagtggtgcctactactggacctggatccggcagcccgccgggaagggattggagtggctcgggcgtgtttatagtggtGGGgggatcatcaattacagtccctccctcaagagtcgaatcaccatgtcgatagacacgtccaagaaccagttctccctgaagttgacctctgtgaccgccgcagacacggccttatattactgtgcgagagaacgtagtgcctcgatgggcgctgcgagagaacttgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +20207 JY8QFUQ01CTE26 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt 97.24 211/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20208 JY8QFUQ01DCVSS productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgGggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +20209 JY8QFUQ01B0HVO No results +20210 JY8QFUQ01BD2L0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20211 JY8QFUQ01C3HRU productive Homsap IGHV3-9*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [1.17.38.11] CAKATTAWYSGGLDVW in-frame + ctctggattcaactttgatgattacggcatgcactgggtccggcaacgcccagggatgggcctggagtgggtcgcaggtattagttataataatggccacaaagaatatgcggactctgtgaggggccgattcaccatctctagagacaacgccaggaagtccctgtatctgcagatggacagtctgagagttgaggacacggccttgtattattgtgcaaaggctacaactgcctggtattcaggcggtctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20212 JY8QFUQ01CZ0MA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGG# out-of-frame - tctggagttcactttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggccaggagcccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20213 JY8QFUQ01DGX5I productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*02 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame + ctctggattcagcttcagtagctacagtatgaactgggtccgccaggctccagggaaggggctggagtggatttcatctattagcaccaccagtagtaccataggctacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagacgaggacacggctgtgtactactgtgccaaagtgggtaacctgtatttctttgaatactggggccggggaaccctggtcaccgtctcccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20214 JY8QFUQ01BQARW productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20215 JY8QFUQ01A53DH productive (see comment) Homsap IGHV3-48*01 F (see comment) 774 84.33 183/217 nt 83.87 182/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [2.17.38.11] CSRDGRRGYDLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) agcctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +20216 JY8QFUQ01CSQFL productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20217 JY8QFUQ01CRKLK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-10*02 F 2 8 8 13 8.8.13 [1.17.38.11] CAKERDNNVLPVDSW in-frame + Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcagcttcaatagttatactttgagttgggtccgccaggctccagggaaggggctggagtgggtctcagctatcagtggaacaggtgaaacaaccttctacgcggactccgtgaggggccggttcaccgtctccagagacaatttcaagaatactctgtacttgcaattgagcgacctgagagccgaagacacggccgtctattactgtgcgaaggagagagataacaatgttctgcccgttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20218 JY8QFUQ01AR0FB unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20219 JY8QFUQ01CNVVI unproductive (see comment) Homsap IGHV4-39*03 F 929 91.36 201/220 nt 90.91 200/220 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSITLTVVVMND#AFDVW out-of-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcCccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgattgcttttgatgtctggggccaagggacattgatcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +20220 JY8QFUQ01BWCR5 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-7*02 F 101 57.65 49/85 nt 8 2 X 8.2.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc +20221 JY8QFUQ01C5GV2 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*03 F or Homsap IGHV4-59*07 F 477 93.58 102/109 nt 92.66 101/109 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 X 15 8.X.15 [1.15.11.11] CAKNNNDFGDYDWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 106 nucleotides (from position 77 in the user submitted sequence), (cause frameshift) tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttaaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20222 JY8QFUQ01C99YD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 770 82.38 187/227 nt 81.06 184/227 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [4.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); gtggccaatgtctgggattcacatttagaagctattccatgaattgggtccgGccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgCcacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaGgggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20223 JY8QFUQ01AR5R2 productive (see comment) Homsap IGHV3-7*01 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [0.16.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 76 in the user submitted sequence), (cause frameshift) tctggatcacctttagcagctatgccatgacctgggttcgccaggctccagggaaggggctggaatgggtggccacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20224 JY8QFUQ01C15XA No results +20225 JY8QFUQ01C32U2 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD4-17*01 F 2 8 7 18 8.7.18 [1.17.38.11] CASLVTINDNGDYTWAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'TT' (2 nucleotides at position 48 to 49 in the user submitted sequence), (cause frameshift); tggatggtgggtccttcagtaataagtattggagttggattcgccagTTccccagggaagggggctagagtggattggagaaatcaaccaaagtggaagcaccaactacaatccgtccctcatgagtcgagtcaccatctccatagacacgtccaagatgcagttctccctgaagttgacctctgtgaccgccgcggacacggctgtctattattgtgcgagtttagtgaccattaatgacaacggtgactacacgtgggcttttgatgtctgggcccaagggacaatggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20226 JY8QFUQ01B0486 productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20227 JY8QFUQ01BTOHO No results +20228 JY8QFUQ01CB6VS unknown (see comment) Homsap IGHV4-4*07 F 796 85.65 185/216 nt 84.26 182/216 nt Homsap IGHJ6*01 F, or Homsap IGHJ6*02 F or Homsap IGHJ6*03 F or Homsap IGHJ6*04 F (see comment) 30 100.0 6/6 nt 8 7 X 8.7.X [2.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 35 of V-REGION: 'CAGTGG' (6 nucleotides at position 21 to 26 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); gtctctggaggctccatcagCAGTGGaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtggGgggtgtcgactacaaccccGtccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagaggattact +20229 JY8QFUQ01CRRE7 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CAREKGSGPPTGMDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20230 JY8QFUQ01BNF8E No results +20231 JY8QFUQ01COUX7 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 977 94.5 206/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); gttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctCggtgactctgacaccagaCtacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaatcccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20232 JY8QFUQ01BMH14 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 718 82.16 175/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDWGGSFDRYYFDYW in-frame + Low V-REGION identity (82,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release caccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +20233 JY8QFUQ01APTJL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20234 JY8QFUQ01BNV0X productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20235 JY8QFUQ01B0DBV No results +20236 JY8QFUQ01B9VA3 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20237 JY8QFUQ01DGA6N unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 92 90.91 20/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggattccctttcagcaa +20238 JY8QFUQ01BXB4P productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); tctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20239 JY8QFUQ01CN9HT productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*05 F 975 95.33 204/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 3 8 8 21 8.8.21 [0.17.38.11] CAGDRGPVFGVVHIGQIYGLDVW in-frame - tggatacaccttcaccaactactatcttcactgggtgcgacaggcccccggacaagggcttgagtggatgggacggatcaacccaaacagtggtggcacaacctatgcacagaagtttcagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgagcaggctgagatctgacgacacggccgtctattactgtgcgggagatcggggtccggtttttggggtggttcatataggccaaatctacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20240 JY8QFUQ01BL4JX productive (see comment) Homsap IGHV3-7*01 F 851 87.67 192/219 nt 87.21 191/219 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.17.38.11] CVRDRPGGWALDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'TG' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift); gcctctggattcagttttagtgacttttggatgcactgggtccgccaggcnccagggaaTGggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20241 JY8QFUQ01CMP43 No results +20242 JY8QFUQ01C5LWY productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +20243 JY8QFUQ01CTB3A productive (see comment) Homsap IGHV4-34*10 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 153 to 153 in the user submitted sequence), (cause frameshift); tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccGaaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20244 JY8QFUQ01AATZ4 productive Homsap IGHV1-2*02 F 826 87.79 187/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [X.17.38.11] CARDGISMTLVRGVRPFDYW in-frame + ggatacaccttcatcggccattatatacattgggtgcgacaggcccctggacaagggcttgaatgggtggggtggatcaaccctaacagtggtgttacaaactatgcacagcagtttcaggacagggtcaccatgaccgtcgacacgtccatcagcactgcctacatggacctcaaaagtctaaagtctgacgacacggccatctattactgtgcgagagacggaataagtatgactctggttcggggagttaggcccttcgactactggggccagggaaccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccccagga +20245 JY8QFUQ01DKEXG unproductive Homsap IGHV4-59*03 F (see comment) 728 82.33 177/215 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD3-9*01 F 2 8 7 X 8.7.X [1.17.38.11] CAREGPPISDIFDWIS##DPW out-of-frame + Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tttctggtggctccatcagaagttactattggagttgggtccggcagtccccagggacgggactggaatggattgggtacaagttctacagtgggcccgccaaatataatccctctctcgagggtcgagtcacaatttctatagacacgtcgaagagtcaattcttcctgaggatgacgtctgtcaccactgcggacacggccgtctattattgtgcgagagagggaccccctatttccgacatttttgactggatcagcaatcgacccctggggccagggaatcccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20246 JY8QFUQ01AWKLD No results +20247 JY8QFUQ01BR7ZQ No results +20248 JY8QFUQ01ACIZJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaataaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20249 JY8QFUQ01B455L unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtagttactggatgcactgggtccgccaaactccagGgggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccaggggaaccctggtcacagtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20250 JY8QFUQ01ARZQB productive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1007 94.64 212/224 nt Homsap IGHJ6*01 F (see comment) 180 76.19 48/63 nt Homsap IGHD4-11*01 ORF 3 8 10 18 8.10.18 [1.17.38.11] CVRHEGTPVSDVGGYGMDVW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtggctctgctatgcactgggtccgccaggtttccgggaaagggctggagtgggttggccgtattagaagcaaagcttacaattccgcgacagcatatgctgcgtcggtgaaaggcaggttcaccatctccagagatgattcaaagaacacggcgtatttggaaatgaacagtttgaagagggaggacacggccgtgtattactgtgtgagacatgaagggactccagtaagtgatgtaggtggatacggcatggacgtctggggtcaagggtccacggtcaccgtctcctcagcatccccgaccagcccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggccttcttcccccc +20251 JY8QFUQ01B27YH unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); cctccggattcaccGtttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccatggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttctttcccccca +20252 JY8QFUQ01DGZF9 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGKMVSTGMDV## out-of-frame - cctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagcctgagggccgaggacacggccgtgtattactgtgcgcgagggaagatggtgagcaccggtatggacgtctgggggccaagggaccacggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20253 JY8QFUQ01BINTH unknown (see comment) Homsap IGHV1-3*01 F 742 92.94 158/170 nt 92.35 157/170 nt 8 8 X 8.8.X [0.17.23.X] null + No rearrangement found in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); tggatacaccttcactagttTttagtatacattgggtgcgccaggcccccggacagaggcttgagtggatgggatggatcaacgcaggcaacggtcacacaaaatattcacagaagttccaggacagagtcaccattataagggacacatccgcgagcacagcctacatgg +20254 JY8QFUQ01A70MJ No results +20255 JY8QFUQ01BOUTJ unproductive (see comment) Homsap IGHV3-7*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + stop codons in FR2-IMGT at codon 54 of V-REGION: 'CC' (2 nucleotides at position 76 to 77 in the user submitted sequence), (cause frameshift); ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcCCcacataaaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +20256 JY8QFUQ01BTE28 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRRGW*RAD#DAFDIW out-of-frame + stop codons ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaaggggatggtagcgggcagatatgatgcttttgatatctggggccgaggggctatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20257 JY8QFUQ01AQI41 No results +20258 JY8QFUQ01B6R3H No results +20259 JY8QFUQ01BU71A unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 811 85.84 188/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found cctgctggattcagttttagttcttatggcatgaactgggtccgccaggcgtccaggggggggctggagtgggtctcattcattaacagtgttagtagttacaaatactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaagaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagatagcggctcgtccgactacactagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20260 JY8QFUQ01DE6Z2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKENYFESSGYHGMNVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcacctttaccaactatgccatgacctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtaatcgtggtactggagtgtactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagagccgaggacacggccctttattactgtgcgaaagagaattactttgagagtagtggttatcacggtatgaacgtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20261 JY8QFUQ01AODBY No results +20262 JY8QFUQ01A6BXT productive Homsap IGHV3-9*01 F 896 90.37 197/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRQAYYHDSSAYFFSRYWYFDLW in-frame + cctctggattcacttttgatgactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacgccaagaagtccctgtttctgcaaattaaaagtctgagagttgaggacacggccttatattattgtgtgaggcaagcgtattaccatgatagcagtgcttacttcttctcccgctactggtacttcgatctctggggccgtggcaccccggtcactgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20263 JY8QFUQ01B8IUW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-8*02 F 2 8 8 20 8.8.20 [1.17.38.11] CARDLWLCSGGECYHRGGFENW in-frame + cctctgggttcaccttcagtaactcctggatgcactgggtccgccaagctccagggaaggggccggagtgggtctcacgtattaatagtgatgggagtaatacaatctacgcggactccgtgaagggccgactcaccatctccagagacaacgccaaaaacacggtgtatctgcaattgaacagtctgagagccgaggacacggctgtgtactactgtgcaagagatctgtggctttgtagtggtggtgaatgctatcatcggggtggttttgagaactggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +20264 JY8QFUQ01CDA2Z productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 842 87.61 191/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-8*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDRIGSLYYFDHW in-frame - cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacagcaaaaactccctgtatctgcaaatgaacagtctgagaactgaggacaccgccttgtattactgtgcaaaagataggattgggtccttgtactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20265 JY8QFUQ01C7XX1 unproductive Homsap IGHV4-61*08 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD5-24*01 ORF 1 10 7 X 10.7.X [0.17.38.11] CARGRDAYKVGY## out-of-frame - in FR3-IMGT at codon 87 of V-REGION: 'G' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift); ctggtgactccgccagcagtggtgattcgtactggagctggatccggcagcccccagggaagggactggagtggattggatatatctataagagtggggacaccgattataacccctccctcaggagtcgagtcaccatatcagtggacacgtccaagacccagGttttccctgaagctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgaggggaagagatgcctacaaggtgggctactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +20266 JY8QFUQ01B829A productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 935 91.07 204/224 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [4.17.38.11] CARGPRSRGYGMDVW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01B829A ; 7 AA in Homsap_IGHV3-53*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20267 JY8QFUQ01AIGWM No results +20268 JY8QFUQ01BSJ22 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20269 JY8QFUQ01B76XK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-21*02 F 2 8 8 13 8.8.13 [1.17.38.11] CATIPSYCGGDCYYW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctttaccttgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgctagtggtttcatctactacgcagactcagtgaggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatggacagcctgagagccgaggacacggctgtatactactgtgcgaccatcccttcgtattgtggtggtgactgctattactggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +20270 JY8QFUQ01C6LLM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +20271 JY8QFUQ01BAL9L productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 811 85.84 188/219 nt 85.39 187/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); gcctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcCggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20272 JY8QFUQ01AQSJN unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARVGYGYRGIYFFDY## out-of-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccagtgacggtgtcgtggaactcag +20273 JY8QFUQ01AYH5R productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*02 F or Homsap IGHV3-33*06 F 900 90.78 197/217 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD3-3*01 F 3 8 8 22 8.8.22 [1.17.38.11] CARDFLAPNRFGVFDYYYYGMDVW in-frame + gtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaggggtctggaatggttggcaatgatatggtatgatggaaataaaaaatactacgcagactccgcgacgggccaattcaccatctccagagacaattctgagtacacgctgtctcttcaaatgaacagcctgagagtcgaggacacggctgtctattactgtgcgagggatttcttagccccgaatcgttttggagtgtttgactactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggccttcttcccc +20274 JY8QFUQ01ADPM4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20275 JY8QFUQ01CB22S unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 995 95.41 208/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDRYTDSWFNGNWFA#PG out-of-frame - cctctggattcacatttgatgaatatggcatgagctgggtccgccaatctccagggaaggggctggagtgggtctctggtattaattggaatggtgccagcataggttatgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtttctgcaaatgaacagtctgagagccgaagacacggccttgtactactgtgtgagagacaggtataccgacagttggtttaatggaaactggttcgccccctgggggccagggaacccaagtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20276 JY8QFUQ01C74AC productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20277 JY8QFUQ01CGEVE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20278 JY8QFUQ01DK586 productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20279 JY8QFUQ01CNIG1 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtacttactactggacatGggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20280 JY8QFUQ01BFUCU No results +20281 JY8QFUQ01CT8CG productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20282 JY8QFUQ01AVNE7 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt 92.69 203/219 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARPFSGRWCFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'AT' (2 nucleotides at position 84 to 85 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtGctcacgaaATtcaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +20283 JY8QFUQ01CIZDC productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame - cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20284 JY8QFUQ01CT1G7 productive Homsap IGHV4-59*10 F, or Homsap IGHV4-61*02 F (see comment) 560 71.74 165/230 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [6.17.38.11] CARERDKSGGGAGDFDSW in-frame + Low V-REGION identity (71,74% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccagtggcattattaatagcgaaggttttggtcgtttctactggaactgggtccggcagatcgacgggcaggggctggagtggatcgggcgtgtttatcgtgatgggatcacaaactacaatccctccttcgggacccgaataagtttgtcgttagactcgtccaagaggcagttttccctgaagttacagtctgtgaccgccgcagacacggccgtatatttttgtgcgagggagcgtgacaagtcgggcggcggggcgggcgactttgactcctggggccagggactcctggtcaccgtctcatctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc +20285 JY8QFUQ01AZYPY unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD2-21*02 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGG*HSDY in-frame + stop codons tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggctgacattcggactactgggccgggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggccaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +20286 JY8QFUQ01CK0JO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 913 91.67 198/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 21 8.8.21 [1.17.38.11] CVRVGAPYYDFWSGYQTNWFDPW in-frame - tctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgcaagtactacttccatacattatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggcgccatattacgatttctggagtggctatcagactaactggttcgacccctggggccagggaactctggtcaccgttacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20287 JY8QFUQ01B5S7F unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccagttttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20288 JY8QFUQ01BC3E1 unknown (see comment) Homsap IGHV3-74*03 F 99 52.59 71/135 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons cctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20289 JY8QFUQ01ASDKR productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20290 JY8QFUQ01BBGWR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-21*01 F 3 8 8 16 8.8.16 [2.17.38.11] CARGRIVSVGMSGWFDPW in-frame - ggctctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtttattactgtgcgagaggccgaatagtgtcggttggtatgtcaggctggttcgacccctggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20291 JY8QFUQ01DHJ8A productive (see comment) Homsap IGHV4-39*02 F 828 93.16 177/190 nt 92.11 175/190 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.6.38.11] CARIVVRQFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 43 of V-REGION: 31 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tctctggtgactccatttccagtactagttattactggGggctggattcggggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20292 JY8QFUQ01DVDK3 No results +20293 JY8QFUQ01A8NL2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctcccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgga +20294 JY8QFUQ01ALPR0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt 85.65 185/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-16*01 F 1 8 7 14 8.7.14 [2.17.38.11] CARCKSAGLVDWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) gcctctggattcagcattagcgactatgccatggcctgggtccgccaggctccagggaaggGggccggagtgggtctcaagtgttactaatggttttggcacatactacgcagactctgtgaagggccggttcaccgcctccagagacaattccaagaacgcattgttcttggaaatgaacatcctcagagccgaggacacggccgtatattattgtgcgaggtgtaagtcggccggtttggtggactggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20295 JY8QFUQ01C4YII productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 768 82.96 185/223 nt 82.51 184/223 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [4.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); atgcaaagtctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctccatccaagcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20296 JY8QFUQ01BXMZI productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame + ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +20297 JY8QFUQ01C5P5J No results +20298 JY8QFUQ01BA216 productive (see comment) Homsap IGHV3-30*01 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggGggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20299 JY8QFUQ01C2VFE unknown (see comment) Homsap IGHV3-13*01 F (see comment) 361 67.63 117/173 nt 8 7 X 8.7.X [1.17.24.X] null + No rearrangement found stop codons Low V-REGION identity (67,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ccgctggattcaccctcagttcctacgacatgcactgggtccgccagactacaggaaaaggtctggagtgggtctcaggtataagcactgacggtgacacatactattcaggctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20300 JY8QFUQ01AJXDQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 1 8 8 14 8.8.14 [1.17.38.11] CAKGRPTASWIYLDDW in-frame + ctctggattcgctcttagcagctatgccatgacctgggtccgccaggccccagggaaggggctggagtgggtcgcatctattagtggtagtggtggtagcacatactatgcagattccgtgaagggccggttcaccatctccagagacaattccaagaacatgctgtctctgcaaatgaacggcctgagagccgaggacacggccttttattattgtgcgaaagggaggcctacagcttcttggatctaccttgacgactggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20301 JY8QFUQ01AX74V unproductive Homsap IGHV3-9*01 F 919 91.32 200/219 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [2.17.38.11] CAKLTYYDVGDY## out-of-frame + cctcgggggttcacctttgatgatcatgccatgcactgggtccggcaagttccagggaagggcctagagtgggtctcaggcattagttggaacagtggtactaaagtctatgcggactctgtgaagggccggttcaccatctccagagacaacaccaagaactccctgtatctccaaatggacagtctgagagctgaggacacggccttgtattactgtgcaaaactcacatattacgatgttggtgactattggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20302 JY8QFUQ01B05AB productive Homsap IGHV4-4*01 F, or Homsap IGHV4-4*02 F or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 883 89.5 196/219 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 2 9 7 14 9.7.14 [2.17.38.11] CARDKDVTARGTFDMW in-frame - gtctctggtgtctccatcagtagtaattactggtggatttgggtccgccagtccccaggggaggggctggagtggattggagaagtctatcatactgggaccacctattacaacccgtccctgaagagtcgagtcaccctgtcagtagacaagtccaggaatcagttctccctggagatgacttctgtgaccgccgcggacacggccgtgtatttctgtgcgagagataaagacgtgacagctcgtgggacctttgatatgtggggccaggggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20303 JY8QFUQ01CKX6X productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 889 91.08 194/213 nt 90.61 193/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD4-23*01 ORF 3 8 6 12 8.6.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) ttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgtttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgc +20304 JY8QFUQ01CMYD1 unproductive Homsap IGHV3-30*01 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGVTKARYGLDV## out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggGggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctgggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20305 JY8QFUQ01B6ERE productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*02 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*04 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*08 F or Homsap IGHV3-30*09 F or Homsap IGHV3-30*10 F or Homsap IGHV3-30*11 F or Homsap IGHV3-30*16 F or Homsap IGHV3-30*17 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F (see comment) 210 83.61 51/61 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 142 76.0 38/50 nt Homsap IGHD3-16*01 F 2 X X 19 X.X.19 [X.X.20.11] CATDLVTSTPGVLDDAYALFG in-frame - Low V-REGION identity (83,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gaacactgtgtatctgcaaatgaacagtctgagagttgacgactcggctctatatcgctgtgcgacagacttggtgacctccacaccgggagtcctcgatgatgcttatgccctttttgggggccaagggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20306 JY8QFUQ01C5JTV unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 845 88.37 190/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 7 X 8.7.X [1.17.38.11] CTRGRSDAWELSDH## out-of-frame - tcgacgatgggtcctgcagaaactgcttctggagttggatccgccagtccccagggaaggggctggagtggattggggaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagtcgagtcaccatatcattagacacgtccaacaaccaagtctccctgaggttgagctctgtgaccgccgcggacacggctgtgtattactgtacgcgagggcgatccgacgcgtgggaattatcggaccactgggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20307 JY8QFUQ01ABKI9 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1085 100.0 218/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [0.17.38.11] CARSRTFYGSANYW in-frame - ctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcgacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20308 JY8QFUQ01CP3ZC productive (see comment) Homsap IGHV3-11*01 F 798 85.0 187/220 nt 84.55 186/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 3 8 8 16 8.8.16 [2.17.38.11] CVRDGARRTNQWLAHDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); agcctctggattcagctttaatgccttctatatgggttgggtccgccaggctccaggaaaggGggctggagtggatttcgtacattaactctggtggtagtgacacatattacgcagactctgtgaagggccgattcaccatctccagggacaacgcctgggacacaatgtacttggaaatgaacagcctgagagccgaagacacggccgtctactattgtgtgagagatggcgctagaaggacgaatcagtggctggcccatgacttctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20309 JY8QFUQ01CM1FF productive Homsap IGHV1-24*01 F 993 96.26 206/214 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [0.17.38.11] CAIGAMATW in-frame - cggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20310 JY8QFUQ01AK0KO productive (see comment) Homsap IGHV3-72*01 F (see comment) 800 84.38 189/224 nt 83.93 188/224 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 1 8 10 12 8.10.12 [1.17.38.11] CARDLGNGWGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 54 of V-REGION: 'TG' (2 nucleotides at position 75 to 76 in the user submitted sequence), (cause frameshift); cctctggattctccttcagggaccactatattgactgggtccgccaagctccaggaaagggactggagtggcttTGgcccgttctagaaccaaagcaaccggtggcgcctcagaatatgccgcgtctgtgaagggcaggttcaccatctccagagacgattcaaggaactcagtgcatctactattgaataacctgaaaagcgatgacacggccatgtatttctgtgctagagatctgggcaacggctggggcttggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20311 JY8QFUQ01CQQNC No results +20312 JY8QFUQ01C2IAV No results +20313 JY8QFUQ01ATFEQ productive Homsap IGHV3-30-3*01 F, or Homsap IGHV3-30-3*02 F (see comment) 407 79.39 104/131 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 X 5 18 X.5.18 [X.X.38.11] CARDDFYSSGNYGGFGMDVW in-frame - Low V-REGION identity (79,39% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaccttcagtcactatgactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20314 JY8QFUQ01B4GVE No results +20315 JY8QFUQ01AUENE productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatcgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcaggc +20316 JY8QFUQ01AS6DO productive (see comment) Homsap IGHV4-39*02 F 920 90.95 201/221 nt 90.05 199/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 3 10 7 14 10.7.14 [1.17.38.11] CARPGARETNNAWVDW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift); tctctggtggGctccgtcagtaggagtccctactactggggctGggatccgccagcccccagggaaggggctggagtggattgggaccatctattatagtgggaccacatactccaatccgtccctcaagactcgagtcaccatgtccttggacacgtccaagaaccacatctccctgaagctgaattctgtgaccgccgcagacacggctgtttattactgtgcgagacctggggctagggagactaataacgcctgggtcgactggggccagggcaccctggtcaccgtctcctcggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20317 JY8QFUQ01AMI66 productive (see comment) Homsap IGHV4-4*07 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [1.17.38.11] CARGKDYYDSTGSLEDGLDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); tctctggtggctCccctcagtacttactactggaactgggtccggcagcccgccgggaagggactggagtggattgggcgtaaatatcccagtggggacaccaactataatccctccctcaaaagtcgagtcaccatgtcactagacacgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagagggaaggattactatgatagtactggttccctcgaggatggtcttgatatctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +20318 JY8QFUQ01BOM4G productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 932 92.2 201/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctgcctcagcatccccggacccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +20319 JY8QFUQ01CUGKT unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggggggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +20320 JY8QFUQ01CDTYL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 811 85.84 188/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20321 JY8QFUQ01BM8I4 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20322 JY8QFUQ01B5HNR unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 86 78.57 22/28 nt 7 X X 7.X.X [2.X.X.X] null + No rearrangement found tctccgggggacagtgtctctaccaaca +20323 JY8QFUQ01BGHS2 No results +20324 JY8QFUQ01AHMW7 No results +20325 JY8QFUQ01CUYHV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD3-22*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKGWNYHSATFWVLTTG in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 79 of V-REGION: 'T' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 180 to 180 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtgactatgccataagctgggtccgccaggctccaggaaaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccattTttcagagacaactccaaagacacgctgtatctgcaaatTgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaaccttttgggttttgactactgggggccagggaaccctggtcaccgtcgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20326 JY8QFUQ01AS1OO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20327 JY8QFUQ01B35QV productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 899 91.16 196/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatatcagtggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20328 JY8QFUQ01AWLSJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame + tctctggattcaccttcatcagttatggcatgagttgggtccgccagtttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccttatattactgtatgaacgaactcggatattgtagtggtgggggggcccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20329 JY8QFUQ01A9JML unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt 90.37 197/218 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); ctccaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatacCtggtggtagcaAcagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20330 JY8QFUQ01BU1XC No results +20331 JY8QFUQ01AMBSZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKEGPTLLTRPPLNW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaacttttggtggtagtggtggttctacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctatatcttcaaatgagcagcctgagagccgaggacacggccatatacttctgtgcgaaagaaggacctacgcttctaactcgcccccctctcaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20332 JY8QFUQ01B9UWP unknown (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20333 JY8QFUQ01DKE1M productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20334 JY8QFUQ01BHEC4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 932 94.26 197/209 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 6 8 16 6.8.16 [X.17.38.11] CARGRIVSVGMSGWFDPW in-frame + tcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20335 JY8QFUQ01BXE8C productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); ctctggattcaccttcGagtgtccatagcatgaactgggtccgccaggctccagGggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20336 JY8QFUQ01CQFMR unproductive (see comment) Homsap IGHV3-7*01 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + stop codons in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaaataaaaacaacatggaggtgaaaaCgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtgggaactcag +20337 JY8QFUQ01BMG0Y productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 797 85.32 186/218 nt 83.94 183/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [2.15.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 42 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 76 in the user submitted sequence), (cause frameshift) gtctctggtgactccatcagtagtactcattactattggggtgatccggcagcccccagggaggggactgagtggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20338 JY8QFUQ01DB8ET productive Homsap IGHV4-61*02 F 880 88.74 197/222 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [2.17.38.11] CARDFGGSYNLVAYW in-frame - gtctctggtgactccatcagtagtgattctcattactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20339 JY8QFUQ01CWLBM unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame - in CDR2-IMGT at codon 62 of V-REGION: 'CG' (2 nucleotides at position 91 to 92 in the user submitted sequence), (cause frameshift); tctggattcactttcagtaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCGgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +20340 JY8QFUQ01BLYHV unknown (see comment) Homsap IGHV3-7*03 F (see comment) 756 82.95 180/217 nt 82.49 179/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggcGtggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +20341 JY8QFUQ01BT61L productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 900 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [1.17.38.11] CNTDLGGSWYTFYSDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 59 of V-REGION: 6 nucleotides (from position 89 in the user submitted sequence), (do not cause frameshift) ctctggatacactgtcataaatgcctggatgagttgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaggtgatggtgtgacaacagaatacgctgcatccgtgaaaggcagattcaccatcacaagagatgactcaaggaacacgttgtatctacaaatgaacagcctgaaaaccgaggacacagccatatattattgcaacacagatctgggcgggagttggtacaccttctattctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag +20342 JY8QFUQ01CIOJM productive Homsap IGHV4-61*03 F 152 66.25 53/80 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 1 X X 13 X.X.13 [X.X.26.11] CATVRHLGERIFDFW in-frame + tctctggggccaccatgagtagtttctactggagctggctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20343 JY8QFUQ01CLZV6 No results +20344 JY8QFUQ01C4TEY productive (see comment) Homsap IGHV1-3*01 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDGESLGGDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); tggatacaccttcagtaattatgctatacattggttgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctagcacgggtaacaCcaaaatattcacagaagttccagggcagagtcaccattaccagggacacagccgcgaccacagcctacatggaattgagcagcctgaaatctgaggacacggccgtgtattactgtgcgagagatggggagtcactgggaggcgactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20345 JY8QFUQ01C3WWM productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20346 JY8QFUQ01DTQKC No results +20347 JY8QFUQ01CK7VZ productive (see comment) Homsap IGHV3-66*02 F 908 91.63 197/215 nt 90.7 195/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaGggctccaggaaAagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20348 JY8QFUQ01CY4TY unknown (see comment) Homsap IGHV3-11*01 F 977 94.5 206/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccagcgggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20349 JY8QFUQ01ACUDT No results +20350 JY8QFUQ01CSGBR productive (see comment) Homsap IGHV3-7*01 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.16.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20351 JY8QFUQ01CDA9C No results +20352 JY8QFUQ01CEW0X productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20353 JY8QFUQ01C1AE4 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 169 76.27 45/59 nt 8 X X 8.X.X [1.10.X.X] null + No rearrangement found ctctggattcaacttcagaacctattggatgggctgggtccgccaggcttcttccccca +20354 JY8QFUQ01B4E92 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 70 of V-REGION: 'A' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'C' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaaAtccgtgcagggCccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20355 JY8QFUQ01CEO2I unproductive (see comment) Homsap IGHV3-7*03 F (see comment) 883 89.04 195/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [2.17.38.11] SRERCVSILL*QLL#DNW out-of-frame + stop codons Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttcgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc +20356 JY8QFUQ01B3QDR productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +20357 JY8QFUQ01ADJF1 unproductive (see comment) Homsap IGHV4-61*02 F (see comment) 780 84.09 185/220 nt 83.64 184/220 nt Homsap IGHJ2*01 F 85 62.26 33/53 nt Homsap IGHD3-16*02 F 1 10 7 X 10.7.X [1.17.37.11] CARGGGSR*YLVLRCL# out-of-frame - stop codons Low V-REGION identity (84,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 117 in the user submitted sequence), (cause frameshift) tctctggttactccatcagtagtggtaatcactactggacctggctccggcagcccgccggggagccactggagtggattgggcgtatccacaccggtgggagtaccaattacaaccctccctccagagtcgagtctccatatcagcagatatattcgagaaccaattttccctgactctggagtctgtgaccgccgcagacgcggccacatattattgtgcgagaggtgggggttctcgttagtatctggtacttcgatgtctgggggccgtggcacccaggtcaatgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +20358 JY8QFUQ01BLEMH productive (see comment) Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 389 90.53 86/95 nt 89.47 85/95 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD5-18*01 F 3 X X 15 X.X.15 [X.X.31.11] CARSDEEYSYGDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'ACTAT' (5 nucleotides at position 22 to 26 in the user submitted sequence), (cause frameshift); cgtctggattcaccttcagtaACTATgagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatcggacgaggaatacagctatggggatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctgggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20359 JY8QFUQ01B23Q1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20360 JY8QFUQ01A2H8S No results +20361 JY8QFUQ01B8SW1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 242 94.34 50/53 nt Homsap IGHD2-21*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVVWSLKKKKKKKKK##WXFDLW out-of-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaactggtncttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtggacggtgtcgtggaactc +20362 JY8QFUQ01A7UAO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccgaagggcccagtcggtccttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20363 JY8QFUQ01ANM3M productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1049 98.17 214/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKDRITIFSYNWFDPW in-frame + cctcgggactcatgtttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggcccctgggctgcctggtccaaggactacttccccgaaccggtgacggtgtcgtggaact +20364 JY8QFUQ01AFVJM productive (see comment) Homsap IGHV3-33*05 F (see comment) 761 83.49 182/218 nt 83.03 181/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); cgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaaaGatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20365 JY8QFUQ01BDUIT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +20366 JY8QFUQ01BBQX1 productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20367 JY8QFUQ01CZ13L No results +20368 JY8QFUQ01BBZEX productive (see comment) Homsap IGHV3-7*01 F 892 89.95 197/219 nt 89.04 195/219 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARVNKDSTDMW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtgactattggatgaggtggttccgccagcctccaggaagGggggctggagtgggtggccagcataaAaagaagatggaagtgagaaaggttatgtggactctgtgaagggccgcttcaccatcgccagagacaacgcccagaaatcactgtttttgcagatgaacagcctgagaggcgaggacacggctgtgtatttctgtgcgagagtcaacaaggactctactgatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc +20369 JY8QFUQ01BX0T4 productive (see comment) Homsap IGHV3-48*03 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDKGWSGYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggCttttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaggagccactcagtgtggac +20370 JY8QFUQ01B0GQK productive Homsap IGHV3-11*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggcagtgctactaccatatcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaaaaactcactttatctgcaaatggacagcctgagagccgaggacacggccatatattactgtgtgaggcgggtgtggggatacagttatggttccgtttcgtactactttgaatactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20371 JY8QFUQ01AJKU7 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 692 80.47 173/215 nt 80.0 172/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 71 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); tctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccCgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +20372 JY8QFUQ01CTZSX unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGGW*R##LDYW out-of-frame - stop codons in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20373 JY8QFUQ01C6PY2 No results +20374 JY8QFUQ01AAWJ6 productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20375 JY8QFUQ01BBO10 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +20376 JY8QFUQ01C560W No results +20377 JY8QFUQ01B4F27 productive (see comment) Homsap IGHV4-61*02 F 897 90.0 198/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.16.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) tctccggtggctccatcagtactggttattactactGggagctggatccggcagtccgccgggaagggactgaatggattgggcgcatgtctgccagagggggAcagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20378 JY8QFUQ01DBGNA No results +20379 JY8QFUQ01AYJTA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20380 JY8QFUQ01DM31W productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20381 JY8QFUQ01ADBUD productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttactggatgcactgggtccgccaanttccagggaAagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccagaaccggtgacggctgtcgtggaact +20382 JY8QFUQ01CN7LI No results +20383 JY8QFUQ01CQPS9 unproductive Homsap IGHV3-11*01 F 862 89.67 191/213 nt 88.26 188/213 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD2-2*01 F 3 8 7 X 8.7.X [1.16.38.11] CARDPYCSSTNCYPY## out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggaTttcaccctcagtgactactacatgagttggttccgccaggctccagggaagggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactgggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20384 JY8QFUQ01AWCVF productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.38.11] CSRLLEEW in-frame + cctctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtcggtcgtcgcatgcctggtccagggcttcttccccc +20385 JY8QFUQ01BT8WJ productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20386 JY8QFUQ01CITZZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKAGYSSARTHMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagcaattttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttgtgagtggtagtggcgatagaacagactacgcagactccgtgaagggccggttcactatctccagagacaattccaagagtacactattcctgcaaatgcacagcctgagagtcgaggacacggccgtatattactgtgcgaaagctggatatagtagtgcgcgaacccacatggacgtctggggccaaggggtcgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20387 JY8QFUQ01B2ORR productive Homsap IGHV4-61*02 F 956 92.76 205/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20388 JY8QFUQ01AH2BL No results +20389 JY8QFUQ01A82FB productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 947 92.31 204/221 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD6-19*01 F 1 10 7 10 10.7.10 [1.17.38.11] CAAYDSGWYKHW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tctctggtggctccgtcaacagtggtgattactactggacctggatccgccagcaccctgggaagggcctggagtggattggatacatctattacagtgggagcacttactacaatccgtccctggagagtcgagttaccatatcaatagacatgtctaagaaccagttctccctgaaagtgagctctgtgactgccgcggatacggccgtgtatcattgtgcggcgtatgacagtggctggtacaaacactggggccagggaaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20390 JY8QFUQ01BFT1Q unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 644 77.06 168/218 nt 76.61 167/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (77,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagGggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20391 JY8QFUQ01DLOLN productive Homsap IGHV3-48*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20392 JY8QFUQ01AB4RA unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1115 100.0 224/224 nt 99.55 223/224 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [2.17.38.11] CARSRTFYGSANY## out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); ctgtctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20393 JY8QFUQ01BFAHV unproductive Homsap IGHV3-72*01 F 1088 98.66 221/224 nt Homsap IGHJ6*04 F (see comment) 108 66.67 36/54 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYDP## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20394 JY8QFUQ01B86US unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 836 87.91 189/215 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 2 8 7 X 8.7.X [1.17.38.11] CAKTTMTSVT#DWFDPW out-of-frame + tctctggggccaccatgagtagtttctactggagctgggttcggcagtccccagggaggggactggagtggattggatttgtttcttacagtgggcccaccaactacagcccctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctgtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagcagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +20395 JY8QFUQ01C793Q unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 728 82.33 177/215 nt 81.86 176/215 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD2-8*02 F 2 8 7 X 8.7.X [1.17.38.11] CARDWGWKLSIGIILTT## out-of-frame + Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); tccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggCacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattgggggtggaagctttcgataggtattattttgactactgggggccaggggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +20396 JY8QFUQ01DKKB4 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20397 JY8QFUQ01CH3UW unknown (see comment) Homsap IGHV1-2*02 F 911 92.45 196/212 nt 91.04 193/212 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.16.37.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 209 in the user submitted sequence), (cause frameshift) tggatacaccttcaccggctactatatgcactgggtgcgacaggcccctggacaaggccttgaaggatgggctggatcGaaccccaacactggtggcacaaattttgcacggcagtttcagggcagggtcgccatgaccagggacacgtccatcaacacagcctacatggacctgaccaggctgcaatctgacgacacggccgtttattctgtgcgagaatttcccatcggggggctagggtacgattttggacgtctggggccacgggacccacagtcaccgtctccctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20398 JY8QFUQ01DA4GB productive Homsap IGHV3-33*04 F (see comment) 703 80.37 176/219 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [2.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcatttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctcag +20399 JY8QFUQ01CJUGP productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatcccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagactgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20400 JY8QFUQ01DF23E unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 777 85.05 182/214 nt 84.58 181/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CARERGSGPP#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 188 to 188 in the user submitted sequence), (cause frameshift); ttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagcCcccgaggacacggccgtctactactgtgcgagagaaagaggttcgggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20401 JY8QFUQ01CUL3S productive (see comment) Homsap IGHV1-2*02 F 925 92.96 198/213 nt 91.55 195/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [X.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'TG' (2 nucleotides at position 41 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 82 to 87 in the user submitted sequence), (do not cause frameshift); ggatacaccttcaccgtctactatctattctgggtgcgacTGgggcccctggacAaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +20402 JY8QFUQ01AFXVN productive (see comment) Homsap IGHV4-4*07 F, or Homsap IGHV4-59*03 F or Homsap IGHV4-59*08 F or Homsap IGHV4-59*10 F or Homsap IGHV4-61*02 F or Homsap IGHV4-61*06 ORF 448 88.6 101/114 nt 87.72 100/114 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 X X 13 X.X.13 [X.X.38.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); aattacagcccctccctcaagagtcgagtcaccaCtttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20403 JY8QFUQ01BICVC unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD3-16*02 F 3 8 7 X 8.7.X [4.17.38.11] CARGAPFS**# out-of-frame + stop codons cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20404 JY8QFUQ01A5MP1 unproductive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1064 98.19 217/221 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 10 7 X 10.7.X [1.17.38.11] CARGGSSGWFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcagcagtggtggttactactggagctggatccgccagcacccagggaagggcctggagtggattgggtacatctattacagtgggagcatctactacaacccgtccctcaagagtcgagttaccatatcagcagacacgtctaagaaccagttctccctgaacctgagctctgtgactgccgcggacacggccgtatattactgtgcgagaggcggtagcagtggctggtttgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20405 JY8QFUQ01BPN8L productive (see comment) Homsap IGHV3-30*01 F 928 91.78 201/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [2.17.38.11] CARDELPWDTIEYYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); gcctctggattcaacttcaggacctattctatgcactggctccgccaggctccaggcaaggggActagagtgggtatcagttatttcatatgatggaactaagaagaattatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctacaaatggacagcctgagacctgaggacacggctgtgtattactgtgcgagagatgaactgccttgggatacaatagagtattactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcacctgcctggtccagggcttcttccc +20406 JY8QFUQ01CG798 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGG# out-of-frame + ctctggattcacttttaggagtcatatgatgagttgggtccgccagactccagggaaggggctggaatgggtctcaagtattcgagccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaactccaagaacacgatgtatttgcaaatgcacagcctgagagtcgacgacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggccagggagccctggtctccgtctgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagccaccccagccagatggggaaacgtggtcatcgcctgcctcgtccagggcttcttcccccag +20407 JY8QFUQ01CLQHG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame + cctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20408 JY8QFUQ01DAGCS No results +20409 JY8QFUQ01B2E18 unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1115 100.0 224/224 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFFGLL# out-of-frame + stop codons cttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20410 JY8QFUQ01CLV9Y productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 909 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'CG' (2 nucleotides at position 52 to 53 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'GTC' (3 nucleotides at position 74 to 76 in the user submitted sequence), (do not cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccCGggggaggggctgggagtgggGTCagtctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20411 JY8QFUQ01BS9UF productive (see comment) Homsap IGHV3-7*01 F (see comment) 728 82.33 177/215 nt 81.4 175/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.16.38.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 63 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 73 in the user submitted sequence), (cause frameshift) ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccgagtgggtgccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagccttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20412 JY8QFUQ01BI2OX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 979 93.69 208/222 nt 92.79 206/222 nt Homsap IGHJ2*01 F (see comment) 94 64.15 34/53 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [3.16.38.11] CARGHSYYVSSGPDYW# out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 101 of V-REGION: 'C' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 83 in the user submitted sequence), (cause frameshift) tgcagcctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcattattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccCctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactgggggccacggaacccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttccccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +20413 JY8QFUQ01B9QB4 unknown (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*07 F or Homsap IGHV4-61*08 F 806 85.32 186/218 nt 84.4 184/218 nt 10 7 X 10.7.X [0.17.38.X] null + No rearrangement found in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'TACGATCCCTCC' (12 nucleotides at position 109 to 120 in the user submitted sequence), (do not cause frameshift); tctctggtggctccgtcagagatttttattactggagttgggtccggcagcCccccagggaagggactggagtggcttggatatctctattacagagggagcaccaagTACGATCCCTCCtataatccctccctcgagagtcgagtcaccatttcagttgacccgtccaagaaccagttctccctgaagctaaactctgtgaccgctgcggacacggccgtgtattactgcgcgagagcctccaccaagggccccaatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +20414 JY8QFUQ01B8WSS productive (see comment) Homsap IGHV4-61*02 F 882 89.86 195/217 nt 88.48 192/217 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 9 7 17 9.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'ATT' (3 nucleotides at position 27 to 29 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 3 nucleotides (from position 26 in the user submitted sequence), (do not cause frameshift) ctctggtgactccatcaccagtggtaATTattattggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcGatcgcacgcaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20415 JY8QFUQ01BOU3T unproductive Homsap IGHV3-30*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CAREGA#FDYW out-of-frame + ctctggattcagtttcagtagctatgcaatgcattgggtccgccaggctccaggcaaggggctagagtgggtgacagttatatcagctgatgcaactaccagtcactacgcagactccgtgaagggccgattcacccactccagagacaattccaagaacacgctgtctctgcaaatggacagcctgagacctgaagacacggctgtatattactgtgcgagagagggggcggatttgactactggggccagggaaccctggtgcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactanttccccgaaccggtgacggtgtcgtggaactc +20416 JY8QFUQ01BM8LC unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 676 87.86 152/173 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttc +20417 JY8QFUQ01BGUPV No results +20418 JY8QFUQ01A87OH unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 338 72.06 98/136 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01A87OH ; 8 AA in Homsap_IGHV3-74*01), and low V-REGION identity (72,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcccctttagtatgtattggatgtattgggtccgccaagctcccgggaaggggccggtatgggtcgcacgtatcagtaatgatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20419 JY8QFUQ01CA881 productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [0.17.38.11] CARGFYGDHFDSW in-frame + tggatacaccttcagcgactactacatacactggctgcgacaggcccctggacaacgacttgagtggatgggatggctgaaccctaataatggtgacacagcttatggccagagctttcagggccgggtcaccatgaccagggacacgtccgtcagcacagtgtacgtggaggtgaggaggctgagatctgacgacacagccctttatttctgtgcgagaggcttttacggtgaccactttgactcctggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20420 JY8QFUQ01CSWD7 unknown (see comment) Homsap IGHV3-7*02 F 118 60.24 50/83 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found cctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20421 JY8QFUQ01CUW2I unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + stop codons ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaaccggtgacggtgtcgtggaactcag +20422 JY8QFUQ01AHIIK unknown (see comment) Homsap IGHV3-66*02 F 748 92.49 160/173 nt 8 7 X 8.7.X [4.17.21.X] null - No rearrangement found tctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgta +20423 JY8QFUQ01CL149 productive Homsap IGHV1-8*02 F 822 87.38 187/214 nt Homsap IGHJ2*01 F 193 84.91 45/53 nt Homsap IGHD2-21*02 F 2 8 8 16 8.8.16 [0.17.38.11] CTTKFGSDWQSDWYFHVW in-frame - tggagacacattccccagccatgacatcaactgggtgcgacaggccactggagaagggcttgagtggatgggacggatgaaccctaagactggtgacacaagctttgcacagaagttccacgatagagtcaccatgatcagtgacacctccataagtacagtgtacatggagctgagtagcctgagatctgaagacacggccatttactattgtacgacaaaattcgggagtgactggcaatcggactggtacttccacgtctggggccgtggcacctcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20424 JY8QFUQ01B2T9Q productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20425 JY8QFUQ01ANXH8 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + cctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20426 JY8QFUQ01BFNST productive (see comment) Homsap IGHV3-48*01 F (see comment) 759 84.11 180/214 nt 83.18 178/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaAaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20427 JY8QFUQ01B5ESG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame - cctctggattctccgtcagtaattactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20428 JY8QFUQ01DA37Z unknown (see comment) Homsap IGHV4-61*01 F 974 93.67 207/221 nt 92.76 205/221 nt 10 7 X 10.7.X [1.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 36 of V-REGION: 'CT' (2 nucleotides at position 28 to 29 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'CTCAAGTATAATC' (13 nucleotides at position 108 to 120 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagagataCTtttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatgtatcacagagggaacaCTCAAGTATAATCccctgtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtcgagagcatcccccgaccagcccccaaggtcttccccgctgagccctctgcagcaccccagcccagatggggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +20429 JY8QFUQ01A3BD5 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 940 93.06 201/216 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [2.17.38.11] CARAPRTATLLDPW in-frame - gtctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20430 JY8QFUQ01B3TLK unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDSPALCLGELF#DYW out-of-frame + in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 177 to 177 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaAatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattccccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20431 JY8QFUQ01A1GBM unproductive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt 82.49 179/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CVKGRGYNDYGLDY## out-of-frame - Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatAttaatgaaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactgggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20432 JY8QFUQ01BQ8XL productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20433 JY8QFUQ01BKJWQ productive Homsap IGHV3-48*01 F 860 88.53 193/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + tctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20434 JY8QFUQ01DI2D1 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 934 93.43 199/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [X.17.38.11] CARDRRGYSYEMDYW in-frame - ggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20435 JY8QFUQ01AHN93 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 937 92.24 202/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gcctctggatcaccctttggttattGatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20436 JY8QFUQ01CBPM3 No results +20437 JY8QFUQ01DSQZ1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20438 JY8QFUQ01BS0BO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.37.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 92 of V-REGION: 1 nucleotides (from position 182 in the user submitted sequence), (cause frameshift) agcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20439 JY8QFUQ01ANL4J productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 942 92.27 203/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame - agcctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaactctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgggtcatcgcctgcctggtccagggcttcttccccca +20440 JY8QFUQ01APFZQ No results +20441 JY8QFUQ01BT21A unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F (see comment) 562 73.15 158/216 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt Homsap IGHD5-18*01 F 3 8 8 X 8.8.X [1.17.38.6] PV## out-of-frame - Low V-REGION identity (73,15% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20442 JY8QFUQ01AP004 unproductive Homsap IGHV4-61*02 F 1028 96.38 213/221 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD6-6*01 F 2 10 7 X 10.7.X [1.17.38.11] CARAPSYTNSHQHCDY## out-of-frame - tctctggtggctccatcaacagtggtagttactactggagttggattcggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctattattgtgcgagagctccctcttataccaactcgcaccagcattgtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggctccttccccca +20443 JY8QFUQ01DBQ71 productive Homsap IGHV3-33*03 F 927 92.17 200/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctcccagccaaggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc +20444 JY8QFUQ01CQO1W productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +20445 JY8QFUQ01CQILL productive Homsap IGHV3-48*01 F 820 86.3 189/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [2.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame - tctctggctttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20446 JY8QFUQ01CN6JB productive Homsap IGHV3-7*01 F 1011 97.2 208/214 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [0.17.38.11] CSNGYGDFPRRW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggattcaccttcaggagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgacaaattctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20447 JY8QFUQ01DTDZS unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CVRGGVSGAFRWGF*LL# out-of-frame + stop codons gcctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgacgacacggctgtttactactgtgtgagagggggagtcagtggggccttcaggtgggggttttgactactgggggccagggaaccctggccaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctggctgcctggtcaggactacttccccgaaccggtgacggtgtcgtggaactca +20448 JY8QFUQ01CGD9R productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 7 8 17 7.8.17 [2.17.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) gcctctggattcagtttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20449 JY8QFUQ01ABZFP productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt 89.14 197/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtggGgaacacctactacaaccCcgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20450 JY8QFUQ01CYDXA No results +20451 JY8QFUQ01CX4NS productive Homsap IGHV4-4*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [1.17.38.11] CARGKDYYDTTGSLEDGFDIW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctctggtggctccataagaagttactattggagttggatacggcactccgccgggaagggactggagtggatcgggcgcatatatgacagtggtagtacaaactacaatccctccctcaagagtcgagtcagcatgtcagtggacacgtccaagaaccaggtctccctgaagttgatctctgtgaccgccgcggacacggccatgtattattgtgcgagagggaaggattactatgatacaactggctccctcgaggatggttttgatatttggggccaagggacgatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20452 JY8QFUQ01BCQMH productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 995 95.41 208/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame - cctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20453 JY8QFUQ01AK0D3 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 872 89.77 193/215 nt 88.84 191/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaggaattattactggagctggatccggcagTcccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaaccCcctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc +20454 JY8QFUQ01CUK5M productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 888 89.55 197/220 nt 88.18 194/220 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [2.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AAA' (3 nucleotides at position 61 to 63 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); ggggtctggatacatctttaatatccactggatcgcctgGggtccgccagatgccccgggAAAagggcctggagtggatggGggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20455 JY8QFUQ01B9DK5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 861 88.18 194/220 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD2-2*01 F 3 10 7 14 10.7.14 [1.17.38.11] CVRIVVPAHTMLFDPW in-frame + ttctggtggctacatcaccagtaccagttacttctggggctggatccgccagcccccggggaagggcctggagtggattggaagaatctattatagtggaaacacgtactacaatccgtccctcgggagtcgagtcaccatatccatagacacctccaagaagcagttttccctgaaattgcgctctgtgaccaccgcagacacggctgtgtacttctgtgtgaggatagtcgtaccagctcatacaatgttgttcgacccctggggccagggtaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggacgtggtcatcgcctgcctggtccagggctt +20456 JY8QFUQ01CG0LT productive (see comment) Homsap IGHV3-33*03 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 8 8 13 8.8.13 [2.17.38.11] CARSDLSMVRDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'T' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); gcgtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatgaTtttggtatgatggaagccttacatattatgaagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgctgtttctgcaaatgaatagcctgagagtcgaggacacggctctgtattactgtgcgagatccgacctctctatggttagagatcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20457 JY8QFUQ01DSX0H No results +20458 JY8QFUQ01DKNPA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 467 68.37 147/215 nt 67.91 146/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.16.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (68,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) tctggattcacctttcgcagctatgccatgagctgggtccgccaggctccaggaaggggctagagtgggtctcatctatcagtggtagtggtgataaaacaaagtacgcagactccgtgaagggccagggcacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20459 JY8QFUQ01A7ITA No results +20460 JY8QFUQ01BZK8O unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [2.17.38.11] CMNELGYCSGG## out-of-frame + gcctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtggggggggaccagggagccctggtctccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20461 JY8QFUQ01CW0LD productive Homsap IGHV3-7*01 F 950 93.12 203/218 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGHW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +20462 JY8QFUQ01BX4AA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'T' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatTgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20463 JY8QFUQ01A12BY productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattGcacatttagtGaattattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20464 JY8QFUQ01AF4F3 productive (see comment) Homsap IGHV3-48*01 F 860 88.53 193/218 nt 87.61 191/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); tctctggcttcagtttgagtacttataccatGgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggGactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20465 JY8QFUQ01BX5Z0 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 966 92.83 207/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION gtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20466 JY8QFUQ01ATK0M productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20467 JY8QFUQ01ARPRF productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1013 96.33 210/218 nt 95.87 209/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARPGVGASSFIDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); gttctggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaAaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20468 JY8QFUQ01AAWL0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 977 94.5 206/218 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARGLYGYWYFDFW in-frame + gctctggattcatctttaatacctatggcatgacttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattcctgtgcgagggggctctacgggtactggtacttcgatttctggggccgtggcaccccggtcactgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20469 JY8QFUQ01CNI4Y productive Homsap IGHV3-9*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + cctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20470 JY8QFUQ01CGTBP productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 896 90.37 197/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - cctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgagaacgtggtcgtcgcatgcctggtccagggcttcttcccc +20471 JY8QFUQ01CSMYJ productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +20472 JY8QFUQ01ATV4S productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 911 90.5 200/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [3.16.38.11] CTKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) gcagcctctggaTttcgccttcagttggtattggagcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20473 JY8QFUQ01ATF2L productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20474 JY8QFUQ01CTI7H No results +20475 JY8QFUQ01AF66X productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVKGAGTTVNWFDIW in-frame + cctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +20476 JY8QFUQ01BIF6M productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame - tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20477 JY8QFUQ01BWN16 No results +20478 JY8QFUQ01A5FS2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDLTGYSSERNYW in-frame + ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgctgagctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +20479 JY8QFUQ01DN52V unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 765 83.41 181/217 nt 82.95 180/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT at codon 90 of V-REGION: 'G' (1 nucleotides at position 175 to 175 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcaGactgaacagcctgagccccgaggacacggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20480 JY8QFUQ01ALJ8H unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 447 93.14 95/102 nt 8 7 X 8.7.X [1.17.X.X] null + No rearrangement found cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgaca +20481 JY8QFUQ01B4A5P unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCF##SW out-of-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20482 JY8QFUQ01DPFBF unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 957 92.38 206/223 nt 91.03 203/223 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD6-19*01 F 2 8 10 X 8.10.X [1.16.38.11] CTTDIVSQWPVAL# out-of-frame + in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccggggaaggggctggagtggttggccggattaaaagcaaaactgatggtgggacaacagagcacgctgcacccgtgaAaaggcagattcaccatctcaagagatgactcaaaaaaGcacgctgtatctgcaaatgaacagcctgaaaaccgaagacacaggcgtttattattgtaccacagatattgtctcccagtggccggttgcgctggggccagggaacccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20483 JY8QFUQ01AY4V0 productive (see comment) Homsap IGHV3-23*05 F 826 87.79 187/213 nt 86.85 185/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 7 7 10 7.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggatcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20484 JY8QFUQ01APXHX productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggGggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccggagagccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20485 JY8QFUQ01BX1HA unproductive Homsap IGHV3-72*01 F 1088 98.66 221/224 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYD#PG out-of-frame + cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20486 JY8QFUQ01AA0M8 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 950 93.12 203/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctgggaccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20487 JY8QFUQ01CHWP5 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CSIRMLGTTG#DYW out-of-frame + cctctggattcacctttagcagctatgccatggactgggtccgccaggctccagggaaggggctggagtgggtctcagatattactggtggtggtggtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagccgaggatacggccatatattactgttcaataaggatgctgggaactactggtgtgactactggggccagggaacccgtggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca +20488 JY8QFUQ01AQAXR productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*13 F 909 91.24 198/217 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDDFYSSGNYGGFGMDVW in-frame + ctctggattcaccttcagtcactatggtatacactgggtccgccaggctccaggcaaggggctagattgggtggcatttatatcatatgatggaagtaatgagttttacgcagactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20489 JY8QFUQ01CWX1F No results +20490 JY8QFUQ01CPDWK productive Homsap IGHV4-61*02 F 920 90.95 201/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 14 10.7.14 [1.17.38.11] CAREKVVIRPNWFDPW in-frame + tctctggtgactccatcaccagtggtaattattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggatcaccaactacaatccctccctcaagagtcgagtcaccatactattagacacgtccagcaaccggttctccctgaagctcagctctgtgaccgccgcagacacggccgtgtattactgtgcgagagaaaaagtagtgatccgtcccaattggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20491 JY8QFUQ01AEJD0 productive (see comment) Homsap IGHV4-61*02 F 876 90.19 193/214 nt 89.25 191/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 8 7 14 8.7.14 [1.17.38.11] CAREKVVIRPNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'CCAGTG' (6 nucleotides at position 18 to 23 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); ctctggtgactccatcaCCAGTGgtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaaTcccctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagagaaaaagtagtgatccgtcccaactggttcgacccctggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20492 JY8QFUQ01AQYMP unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 824 86.7 189/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CARCFSAWGSGCFRHL# out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagatgcttcagtgcctggggctcaggatgctttcgacatttgggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20493 JY8QFUQ01CZ7ZE productive Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccgatgacggtgtcgtggaact +20494 JY8QFUQ01DBCZB productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 15 10.7.15 [1.17.38.11] CARNPSYSNSHQHCDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'A' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaacagtggtagttactactggagttgggttcggcagcccgccgggaagggactggagtggattgggcgtatctacaccagtgggagcaccaactacaacccctccctcaagagtcgagtcgccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctaAtttttgtgcgagaaatccctcttatagcaattcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +20495 JY8QFUQ01CIMIR productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20496 JY8QFUQ01DK73Q productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 662 77.98 170/218 nt 77.52 169/218 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD3-3*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIIREGLDRW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (77,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); tgtctggtggttctactcgcactaaccattggtggaattgggtccgccagAccccccgacaagggactggagtggattggagaagtctataagagtggacagaccaactacaacccgtcactccagagtcgcgttgacctcttcattgacaactccaggaatcagatctccctaaatatgagagatgtgaccgccgcggacacggccgtctattactgcgcgagagaagacattattcgggagggccttgaccgctggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20497 JY8QFUQ01DU9MT unknown (see comment) Homsap IGHV1-3*01 F 863 89.3 192/215 nt 88.84 191/215 nt 8 8 X 8.8.X [0.17.38.X] null - No rearrangement found in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); ctggatacagcttcactaactacaatatccattgggtgcgccaggGccccccggacaaggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctcggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +20498 JY8QFUQ01CYU9T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + cctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaaactca +20499 JY8QFUQ01BW40A unknown (see comment) Homsap IGHV1-2*02 F 491 87.4 111/127 nt 86.61 110/127 nt 7 8 X 7.8.X [0.17.9.X] null + No rearrangement found in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift) tggatacatttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcaggg +20500 JY8QFUQ01CSNEW No results +20501 JY8QFUQ01BKZA5 productive (see comment) Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt 81.19 177/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggGggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20502 JY8QFUQ01AUOG5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 838 87.21 191/219 nt 86.3 189/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) cctccgggagttcaccttagtagtttctggatgcactGgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20503 JY8QFUQ01BNZIF productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20504 JY8QFUQ01BXIFI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 928 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 79 to 81 in the user submitted sequence), (do not cause frameshift); gcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20505 JY8QFUQ01BKQKN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 813 85.2 190/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 3 8 8 10 8.8.10 [3.17.38.11] CASFRVLESGYW in-frame - tcagtctctgggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20506 JY8QFUQ01CEKK5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20507 JY8QFUQ01BE7MC unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20508 JY8QFUQ01B6OFV productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +20509 JY8QFUQ01CDM5K No results +20510 JY8QFUQ01DOM3L unproductive (see comment) Homsap IGHV4-61*02 F 857 87.78 194/221 nt 87.33 193/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CAREGAWLHLQEV#FDYW out-of-frame + stop codons in CDR2-IMGT at codon 59 of V-REGION: 'ATT' (3 nucleotides at position 96 to 98 in the user submitted sequence), (do not cause frameshift); tctctgacgactccatcagcagtggcacttactactggagttggatccggcagcccgccgggaaggctccggagtggattggccgcttctatactATTactgggcgcaccaactacaatccctccctcgagagtcgagtcaccataacaagggacgtgtccaagaatcagttctccctgagactgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagagagggggcatggctacatctacaagaggtcttttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +20511 JY8QFUQ01DDD61 unproductive (see comment) Homsap IGHV3-7*01 F 980 95.35 205/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttgagattactggggccagggaacccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20512 JY8QFUQ01ANB8J No results +20513 JY8QFUQ01C1JXP unproductive Homsap IGHV3-48*01 F 1065 100.0 214/214 nt 99.53 213/214 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [0.16.38.11] CASRLRSSGGY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) ctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20514 JY8QFUQ01AOJA0 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 901 90.41 198/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [2.17.38.11] CAKDELPWDTIEYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'GA' (2 nucleotides at position 103 to 104 in the user submitted sequence), (cause frameshift); gcctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggttgggtggtcaAcgtagtaatacagggggggactgGAcacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20515 JY8QFUQ01B9QXU productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 835 88.26 188/213 nt 87.79 187/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.37.11] CARKGLVPSMFFFDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 192 in the user submitted sequence), (cause frameshift) ctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccgggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20516 JY8QFUQ01CUAUX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactca +20517 JY8QFUQ01B0M83 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 982 94.52 207/219 nt 93.61 205/219 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [2.17.38.11] CAKVRRSGWSYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); cctctgggattcaccttctttacctatggcatgcactgGggtccgccaggctccaggcaaggGggctggagtgggtggcaattatatcatatgatgtaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagttgaggacacggctgtttattactgtgcgaaggtgcggcgtagtggctggtcctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20518 JY8QFUQ01AEOR4 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 926 90.62 203/224 nt 90.18 202/224 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD3-22*01 F 3 8 10 X 8.10.X [1.17.38.11] CATDRPYYKKRCWPTLVLLRYGR#W out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggGggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaaacgctgctggccgactctggtattactacggtatggacgttttggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20519 JY8QFUQ01CXDJA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.74 200/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKKYHYGSGTYLYYFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactgggggccagggaaccctggtcaccgtctcctcagcattcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20520 JY8QFUQ01AS3A0 No results +20521 JY8QFUQ01B8UD2 No results +20522 JY8QFUQ01AY8EO unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20523 JY8QFUQ01A4BAZ productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag +20524 JY8QFUQ01BZQW7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20525 JY8QFUQ01BHF8T productive Homsap IGHV4-4*07 F 833 87.16 190/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [2.17.38.11] CARQRGGGDRQWAFENW in-frame - ctgtctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20526 JY8QFUQ01B3761 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.14 211/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctaCctggagctGggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20527 JY8QFUQ01CYC0M productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-15*01 F 1 8 7 15 8.7.15 [1.17.38.11] CAKMNGWKLQEYNLDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagatatgccatgagctggattcgccaggctccagggaaggggctggagtgggtctcagctattagtaatagtgatgttacatactatgcagactccgttaagggccggttcaccatctccagagacacttcgaagaacacgctgtatctccaattgagcagcctgagagccgaggacacggccgtgtattactgtgcgaaaatgaatgggtggaagttacaggaatacaacttagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcctgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20528 JY8QFUQ01CBHR0 productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20529 JY8QFUQ01A1AYP productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20530 JY8QFUQ01B3TT1 productive Homsap IGHV1-2*02 F (see comment) 777 84.58 181/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARGLSYDSSPYWGYW in-frame + Low V-REGION identity (84,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacatcttcaatgacttctacatatattgggtgcgacaggcccctggacaagggcttgagtggatgggatggttcaaccctaatagtcgtgtcacagactatgcagagaaatttcagggcagggtcaccatgaccggggacccgtcccgcagcacagtccacctgaaactgacccgcctgaagtcggacgacacggccgtctattactgcgcgagaggtctctcctatgacagtagtccttattggggctactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20531 JY8QFUQ01CTR0D productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20532 JY8QFUQ01CC9ZO productive Homsap IGHV4-4*07 F 962 94.42 203/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 7 17 8.7.17 [1.17.38.11] CARDSSRSYYEGSGRFDQW in-frame + tctctggtggctccatcaggagtgactcctggacctggatccggcagcccgctgggaagggactggagtggattgggcatactcataccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatgtcagtagacacgtccaagaaccagttctccctgaagttgagctctgtgaccgccgcggacacggccgtctattactgtgcgagagattcaagtcgcagttactatgaaggaagtggtcgttttgatcagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +20533 JY8QFUQ01ARNM3 unproductive Homsap IGHV1-8*01 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [0.17.38.11] CARGGLLRDSIGYSYVPHDH## out-of-frame + tggatacactttcaccagttatgatatcatctgggtgcgacaggccactggacaaggacttgagtggatgggatggatgagccctaacagtggtaacacaggctctgcacagaagttccagggcagagtcaccatgtccagggacacctccataagtacagcctacatggagctgagcagcctgagatctgaggacacggccgtttattactgtgcgagaggcggcttgttacgtgatagtattggttattcttacgtcccgcatgaccactggggcccagggatccctggtcaccgtctcctcaacatcccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +20534 JY8QFUQ01CYAE8 No results +20535 JY8QFUQ01CXWS2 unproductive (see comment) Homsap IGHV3-9*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKRRVGDTSDWYLL*IL# out-of-frame + stop codons cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttagaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccaagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgcccctgggctgcctggtcaaaggactacttccccgaaccggtgacggtgtcgt +20536 JY8QFUQ01C30IW productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + cctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgaccggtgtcgtggaactc +20537 JY8QFUQ01CO43H unproductive Homsap IGHV3-7*03 F 851 88.07 192/218 nt Homsap IGHJ5*01 F (see comment) 106 66.67 34/51 nt Homsap IGHD3-16*01 F 1 8 8 X 8.8.X [1.17.38.11] CTRRGFMDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctccggattcatttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggcccaagggaccacggtcaccntctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20538 JY8QFUQ01AQ0OT unproductive Homsap IGHV3-30*01 F 990 95.39 207/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CAREPGRGLYTCN##WYFDLW out-of-frame + ctctggattcaccttcagtagccatgctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgggggttatatcatctgatggaagtaatgaatactatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacactgtatctgcagatgaacagcccgagagctgaggacacggctgtgtattactgtgcgagagagcctgggaggggtttatacacctgcaatgaactggtacttcgatctctggggccgcggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +20539 JY8QFUQ01BQCNP productive (see comment) Homsap IGHV4-61*01 F (see comment) 776 83.71 185/221 nt 83.26 184/221 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagTccccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtccaaggactacttccccgaaccggtgacggtgtcgtggaactc +20540 JY8QFUQ01B48K0 unproductive (see comment) Homsap IGHV4-61*02 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD5-24*01 ORF 2 10 7 14 10.7.14 [0.17.38.11] CARDFRRFLQF*WPTG in-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctggtgactccatcagtagtgattctcactactggagttggatccggcagcCccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttcggaggttcctacaattttagtggcctactggggccagggaacccttggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +20541 JY8QFUQ01CEEMS productive Homsap IGHV3-48*03 F 797 85.32 186/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [1.17.38.11] CVRQTGDYYFFGLDVW in-frame + cctctggattcgccttcaaaagttttaacatgaattgggtccgccaggcttcagggaaggggccggagtggattgcatacattaatggaagagggactaacatctactatgcagactctgtgaagggccggttcaccatctccagagacaacgcccagaacgcagtgcatctgcagatggaccgcctgagagtcgaggacacggccctatattactgtgtgagacaaactggagactactatttcttcggtctggacgtctggggccaaggaaccacggtcaccgtctcttcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20542 JY8QFUQ01A5IKH productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [2.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) tgttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20543 JY8QFUQ01AO571 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGS## out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaTggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagcccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +20544 JY8QFUQ01BFP3C productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +20545 JY8QFUQ01ANOJ3 productive (see comment) Homsap IGHV3-7*01 F 1027 96.8 212/219 nt 96.35 211/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 8 8 8 8.8.8 [2.17.38.11] CGTSRSLDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatgggagtgagaAaatactatgtcgactctgtgaagggccgattcaccatctccagagacaacgccgagaactcactacatttgcaaatgaacagcctgagagccgaagacacggctgtgtattactgtgggacgagcaggtcccttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20546 JY8QFUQ01AU066 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F (see comment) 199 89.58 43/48 nt Homsap IGHD3-10*02 F 2 8 7 X 8.7.X [1.17.38.11] CAKESLFGESSHT#FDDW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) cctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggtttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctgttcggggagtcatctcatacnactttgatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20547 JY8QFUQ01ANXIF productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 973 94.06 206/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDRGCTNGACYVADFW in-frame + gcctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20548 JY8QFUQ01C183I productive (see comment) Homsap IGHV3-30*15 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARNELPWDTREYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctccggattcacctttagtaaatattccatgaactgggtccgccaggctccaggcaAaggggctcgagtgggtggcacttatatcatacgatggaagtagaaaaatctacgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +20549 JY8QFUQ01B6C3B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 845 88.37 190/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [0.17.38.11] CAREVPHQNIIYLDYW in-frame - ctggattcgactttagcagcgcttccatggcctgggtccgccaggctccagggaaggggctggagtggatctcagctgtcagtggacgtggtgacaacaccttctacgcagcctccgtgaagggccggttcaccatctccagagaccattccaagaacacgctgtggcttcaaatgaacaacctgagagccgaagacacggccctatattactgtgcgagggaagtcccacatcaaaatataatctaccttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20550 JY8QFUQ01DAKJF No results +20551 JY8QFUQ01CII6F productive (see comment) Homsap IGHV3-7*01 F 896 90.37 197/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'GC' (2 nucleotides at position 64 to 65 in the user submitted sequence), (cause frameshift); cctctagattcaccTtttaatggttactggatgagttgggtccgccaggctccaggaaaggggGCtgggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20552 JY8QFUQ01A7T6F productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1002 96.73 207/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFYYW in-frame - tggatacaccttcaccagctactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagacttttactactggggccagggaaccctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20553 JY8QFUQ01BYGY7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20554 JY8QFUQ01BLSOB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccaggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20555 JY8QFUQ01BZ30W productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20556 JY8QFUQ01CDHKA productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 928 91.32 200/219 nt 90.41 198/219 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'ATTT' (4 nucleotides at position 102 to 105 in the user submitted sequence), (cause frameshift); gcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaGggggctggagtgggtctcaagtgtcagtagtagtactggttATTTtcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +20557 JY8QFUQ01AU1LL productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARDRRPLREFDCW in-frame - ctctggattcaccctctccagctatgctatgcactgggtccgccagtctcccggcaaggggctagagtgggtggcagctatttcatatgatggaagtaaaatatattacgcagactccgtgaggggccgcttctccatctccagagacagttccaagaacactctgcatttgcaaatggacagcctgagacctgaggacacggctacatattactgtgcgagagatagacggccacttagggagtttgactgttggggccagggaaccccggtcgccgtctcctcggcatccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt +20558 JY8QFUQ01AV820 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20559 JY8QFUQ01BO1PR unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD6-6*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKVV*EP#WYFDLW out-of-frame - stop codons in CDR2-IMGT at codon 62 of V-REGION: 'TT' (2 nucleotides at position 95 to 96 in the user submitted sequence), (cause frameshift); cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggTTtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctaggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20560 JY8QFUQ01CW25E productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGHW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20561 JY8QFUQ01C8M8C unknown (see comment) Homsap IGHV3-30*02 F, or Homsap IGHV3-30*06 F or Homsap IGHV3-30*11 F or Homsap IGHV3-30*12 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-3*02 F or Homsap IGHV3-30-5*02 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*02 F or Homsap IGHV3-33*03 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 83 86.36 19/22 nt 6 X X 6.X.X [1.X.X.X] null + No rearrangement found gtctggattccctttcagtaga +20562 JY8QFUQ01C8O8L No results +20563 JY8QFUQ01B7G97 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRGLW*WCMPCR#DYW out-of-frame - stop codons cctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcgggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20564 JY8QFUQ01AOUGQ productive Homsap IGHV3-11*01 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame + tctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctaagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +20565 JY8QFUQ01B528L productive (see comment) Homsap IGHV3-7*01 F 953 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRDRFYDSSGYEFGELGDYSDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); tctggattcacatttagtaactactggatgagctgggtccgccaggntcCcagggaaggggctggagtgggtggccaacataaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctgtgtgagagatcgattttatgatagtagtggttatgagtttggggaattgggggactactctgaccactggggccagggaacccaggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20566 JY8QFUQ01B20U6 No results +20567 JY8QFUQ01BCXUQ unproductive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*05 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*13 F 956 92.76 205/221 nt 92.31 204/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [2.17.38.11] CAGDLTGGSVLL*Q*WFK#YW out-of-frame - stop codons in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); caccctctggattcaccttGcagtgaccactacatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactgggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttccccgctgaacctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc +20568 JY8QFUQ01DGQF4 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 973 94.06 206/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtagctactggatgcactGgggtccgccaagctccagggaagGgggctggtttgGggtctcacgtgttaatggtgatgGggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +20569 JY8QFUQ01BULZ8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.48 192/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDASRYYYNSYCDN## out-of-frame - ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20570 JY8QFUQ01BX9B3 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1009 95.89 210/219 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [2.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - gcctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20571 JY8QFUQ01CYBYD productive Homsap IGHV3-9*01 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-21*02 F 3 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame - tctggattcacttttgatgactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20572 JY8QFUQ01A455F No results +20573 JY8QFUQ01B2RJO productive Homsap IGHV4-61*02 F 974 93.67 207/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtaacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20574 JY8QFUQ01CGDH8 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame - tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20575 JY8QFUQ01BNYSV productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20576 JY8QFUQ01B3I3D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacatactacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20577 JY8QFUQ01CXXGJ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt 93.61 205/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDCDSGECNFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gcctctggattcagcttcagtacctataacatgaactgGggtccgccaggctccagGggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaaactc +20578 JY8QFUQ01CUZ9J productive Homsap IGHV4-61*02 F 893 89.59 198/221 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARDPRVICSGGSCRSSAMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaacccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagaccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20579 JY8QFUQ01CBOVD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRQLGFGDLFRFD#PW out-of-frame + ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20580 JY8QFUQ01DDAJF No results +20581 JY8QFUQ01BQYII No results +20582 JY8QFUQ01BY7OB productive (see comment) Homsap IGHV3-30*12 F, or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 3 8 7 13 8.7.13 [1.17.38.11] CASSRDGYNHGLRYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 65 of V-REGION: 3 nucleotides (from position 102 in the user submitted sequence), (do not cause frameshift) tgtctggattcaccctcagctcctatggcatgcactgggtccgccgggctccaggcaaggggctagagtgggtggcgaatatgtttcatgatggaggctcttactatggaccctccgtgaggggccgattcaccatctccagagacaattcgaagaacacgctatttctacaaatgaacagcctgagagccgaggacacggctctatattactgtgcgagtagtagagatggctacaatcacggcttgagatactggggccagggaaccctggtcaccgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +20583 JY8QFUQ01ABDA1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [2.17.38.11] CARDRLTISALDYW in-frame - gcctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20584 JY8QFUQ01BODB4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD3-9*01 F 2 8 8 18 8.8.18 [1.17.38.11] CVKVAGDYRTPNYGWHFDLW in-frame - ctctggattcacctttagcacctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggtagtggtggcagcacattctactcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactggatctgcaaatgaatagcctgagaggcgaagacacggccgcatattactgtgtgaaagtggccggtgactatagaactcccaactacggctggcacttcgatctctggggccgaggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20585 JY8QFUQ01AQGFD unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 83 86.36 19/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggactcagtttcactaa +20586 JY8QFUQ01CXVQF unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 92 90.91 20/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggactcaccttcagtgc +20587 JY8QFUQ01CQ144 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 801 85.71 186/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20588 JY8QFUQ01CC4XP productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggagtgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggccagggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20589 JY8QFUQ01CP8K4 productive (see comment) Homsap IGHV4-61*01 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagAcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20590 JY8QFUQ01B5TJY productive Homsap IGHV3-9*01 F 950 93.12 203/218 nt Homsap IGHJ1*01 F (see comment) 143 75.0 39/52 nt Homsap IGHD4-17*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARLPGDYGSRW in-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaactttgataaatatgacatgcactgggtccgacaagctccagggaagggcctggagtgggtctcaggtattaagtggaatggcggtcgcgtcggctatgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagacctgaggacacggccttctattactgtgcaagactccccggtgactacgggtctcgttggggccagggaaccctcatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20591 JY8QFUQ01CCTXA unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P 101 95.45 21/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggattcactttcagtga +20592 JY8QFUQ01BP8CT No results +20593 JY8QFUQ01B2RPV unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 148 91.43 32/35 nt 8 X X 8.X.X [1.2.X.X] null - No rearrangement found ctctggattcacctttagcaactttgccatgacct +20594 JY8QFUQ01BYNMN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-20*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGLTTMTGNGLEHW in-frame + tctctggattcacccttcgcagatatggcatggcgtgggtccgccaggctccggggaaggggctggagtgggtctcatcttctaacagtagtgatgaatccacatactatgcagactccgtgaagggccgcttcaccatttccagagaccattccaagaacacggtgtttttgcaaatgtacagcctgagagccgaagacacggccctctattactgtgcgagagggctaacaacaatgacagggaatggtcttgagcactggggccagggagccctggtcaccgtctcctcaccatccccgaccagccccaaggtnttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20595 JY8QFUQ01A3B8P productive (see comment) Homsap IGHV4-39*02 F 819 86.24 188/218 nt 84.86 185/218 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.16.38.11] CARHVVLDNRYSVWPRILDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'TG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 74 in the user submitted sequence), (cause frameshift) ctctggtgaccccatcggcaacactgcttactcctggggctggatccgcancccccagggaaTGggggctggagtgatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20596 JY8QFUQ01CRRZO No results +20597 JY8QFUQ01CJDWD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20598 JY8QFUQ01CKWXR productive (see comment) Homsap IGHV3-7*01 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); tctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactCctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatatttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20599 JY8QFUQ01B88H9 No results +20600 JY8QFUQ01ANBGV unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDQSCIVGPCGF*LL# out-of-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); cctccgaattcatccttgacagttatgccatgagttgggtccgccaggCccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggtttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20601 JY8QFUQ01DH3P5 productive Homsap IGHV3-21*04 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccagggaatcctggtcaccggtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccga +20602 JY8QFUQ01A5J3G productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20603 JY8QFUQ01B3CAL productive Homsap IGHV3-7*01 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - ggctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20604 JY8QFUQ01CLTLS unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 136 55.47 76/137 nt 10 9 X 10.9.X [1.17.8.X] null + No rearrangement found stop codons ctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +20605 JY8QFUQ01AH284 unproductive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 994 93.78 211/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGDYYDSGGLDYW in-frame + stop codons tccggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtagtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtgattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20606 JY8QFUQ01BDT3E productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 7 8 11 7.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) tctctggattcacctttagtaggtttggatgacctgggtccgccagggtccagggaaGggggctggagtgggtggGccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20607 JY8QFUQ01AKYKZ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 479 82.73 115/139 nt 8 8 X 8.8.X [1.17.12.X] null + No rearrangement found Low V-REGION identity (82,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccgcatactacgcagactccgtgacggtgtcgtggaactca +20608 JY8QFUQ01DH3RW unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKDQSCIVGPCGFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); cctcccgaattcatccttgacagttatgccatgagttgggtccgccaggCccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20609 JY8QFUQ01A96A4 productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20610 JY8QFUQ01A3WY6 unproductive Homsap IGHV3-48*02 F 896 90.37 197/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARGQNGYKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20611 JY8QFUQ01BWLVQ unproductive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F 953 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.37.11] CAKDAMGGAGDWAAFWYL# out-of-frame + in FR3-IMGT, from codon 99 of V-REGION: 2 nucleotides (from position 200 in the user submitted sequence), (cause frameshift) ctctggcttcatctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagcgctaccatagaatatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctggaaatcaacagtctgagacctgaagacggccttatactactgcgcaaaagatgcgatgggaggagctggtgattgggctgctttttggtatctggggccaggggacaattggtcactgtctcttcagccatccccgactcgccccaaggtcttccccgtgagccctccgagcaccccccaaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttccccca +20612 JY8QFUQ01BBV1G productive (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P (see comment) 953 93.95 202/215 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGPHQYYFDYW in-frame + however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01BBV1G ; 7 AA in Homsap_IGHV3-69-1*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactactttgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20613 JY8QFUQ01CEON4 productive Homsap IGHV3-7*01 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATDDSNGWDEVADYW in-frame + cctctggattcaccttcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20614 JY8QFUQ01BQF91 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'GG' (2 nucleotides at position 56 to 57 in the user submitted sequence), (cause frameshift); ctctggattctccgtcagtAagttactggatgcactgggtccgccaggctccaggGGgagggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagattactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +20615 JY8QFUQ01C35W7 unproductive (see comment) Homsap IGHV3-7*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGGW*R##LDYW out-of-frame - stop codons cctctggattcacctttagtaaccattggatgaactgggtccgccaagctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20616 JY8QFUQ01DBTFY No results +20617 JY8QFUQ01DNQJ0 unproductive Homsap IGHV4-39*07 F (see comment) 789 84.55 186/220 nt 84.09 185/220 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-10*01 F 1 9 7 X 9.7.X [2.17.38.11] CARAVLDNAWPIYYDFW# out-of-frame + Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 38 of V-REGION: 2 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) gtgtctggtggctccatcaccacttggcattactgggggctggatccgccagcccccaggggagggtctggaatggattggaaatgtctatcataatggcaatatcgcctatagcccgtcgcagaggagtcgaatcaccatatcagtagacacgtccaggaaccagttctccctgaagatgacctctgtgaccgccgcggacacggctgtctattactgtgcgagggctgttcttgacaatgcctggcctatatattatgacttttgggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +20618 JY8QFUQ01B69TS No results +20619 JY8QFUQ01BASRH productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 895 90.74 196/216 nt 89.81 194/216 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [2.17.38.11] CTRELRVAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); gcctctggattcaccgtcagtaccaaGgttcatgagctgggtccgccaggctccagggaaggGggctggagtgggtctcagtaatttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20620 JY8QFUQ01CS2E5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 97 of V-REGION: 'C' (1 nucleotides at position 197 to 197 in the user submitted sequence), (cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccCgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20621 JY8QFUQ01AYHYC productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20622 JY8QFUQ01AZTNG productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1110 100.0 223/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD4-17*01 F 3 8 10 12 8.10.12 [1.17.38.11] CTKCSVTIYFLTTG in-frame + ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttactttttgactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaactc +20623 JY8QFUQ01A0C33 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); tctggattcaccttcCgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagccctccaccaagggcccatcggtcttccccctggcaccctcctcccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20624 JY8QFUQ01DKHHD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 952 94.37 201/213 nt 93.43 199/213 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 7 8 12 7.8.12 [0.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctacattcgcctttagcactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20625 JY8QFUQ01A4LK9 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 804 84.75 189/223 nt 82.51 184/223 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [2.17.38.11] CARRWARQRLVMDYFDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'GA' (2 nucleotides at position 72 to 73 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'GG' (2 nucleotides at position 81 to 82 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 108 to 108 in the user submitted sequence), (cause frameshift); tgtctctggtgactccatcagtagtactcattactattGggggctggatccggcagccccccagggaggggGActggagtGGggttggggagtatCccactacactgGggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactc +20626 JY8QFUQ01ASRUM unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +20627 JY8QFUQ01CDK3J productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20628 JY8QFUQ01CJF57 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 734 82.11 179/218 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame - Low V-REGION identity (82,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtaaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20629 JY8QFUQ01CIIBR unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [2.17.38.11] CAEKNIIIRGLI#YNFDYW out-of-frame - gcctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcggaaaaaaacattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20630 JY8QFUQ01B1I83 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame - ctctggcattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcacgcctgcctggtccagggcttcttccccca +20631 JY8QFUQ01B1ZKV No results +20632 JY8QFUQ01CDJ94 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt 99.53 214/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttactactggagctggatccggcagcCccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctgtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc +20633 JY8QFUQ01B3G22 productive Homsap IGHV3-7*02 F 904 91.2 197/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame - tctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaaggggcccatcggtnttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20634 JY8QFUQ01CIVFH No results +20635 JY8QFUQ01A6R3G No results +20636 JY8QFUQ01BPJ86 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 836 87.5 189/216 nt 86.57 187/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSGPSGYARYESMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 94 of V-REGION: 'T' (1 nucleotides at position 187 to 187 in the user submitted sequence), (cause frameshift); tctggattcagcctcaCtttcctatggcatgaactgggtccgccaggctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccntgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacctTgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20637 JY8QFUQ01BAEEF unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSSPYFYDSNGY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcatcttcagtaaatataccatgaaatgggtccgccaggctccagggaaggGggctggagtgggtctcatccatcagtagtagtagtggttacatatactactcagattcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20638 JY8QFUQ01AXH9R unproductive (see comment) Homsap IGHV1-18*01 F (see comment) 743 83.81 176/210 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD2-21*02 F 3 7 8 17 7.8.17 [X.17.38.11] CVREESIVVVTGRRGMDVW in-frame - stop codons Low V-REGION identity (83,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ggttagttntacacctctgtgttcagctgggtgcgacaggcccctggacaaggcctggagtggatgggatgggtcagcggttataatgataaatccaactatgcacagaagttcaaagacagaattatcatgaccacagacatatcaacgagcacagcctacatggagctgaggagcctgagatctgacgacacggccatgtattattgtgttagagaagagtcaattgtggtggtgaccgggcggcggggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20639 JY8QFUQ01CMW48 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 974 93.67 207/221 nt 93.21 206/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARHGSGWLQELDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtggctccatcatcagagacagtgcctactGggggctggatccgccagcccccagggaaggggctggagtggcttgggagcatctattatagtgggagtacctactacaatccctccctcaagagtcgagtcaccatatccgtagacacgtccaagaagcagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagacatggcagtggctggctccaggaacttgactactggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20640 JY8QFUQ01BY1FZ productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.16.38.11] CARLPNTIDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 77 in the user submitted sequence), (cause frameshift) ttctggatatagttttgccacctactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccgggtcaccatttcagccgacaagtccctcagtatcgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagactgcctaacactattgactcctggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20641 JY8QFUQ01CFAIY productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 909 91.24 198/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKVSGNSRTYWYLDIW in-frame + ttctggatacaactttcccagatattggatcgcctgggtgcgccagattcccgggagaggcctggagtgggtggggatgatctatcctggtgactctgagaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacgcgtccatgaacaccgcctacctgcagtggagcagcctgaaggcctccgacaccgccatatacttctgtgcgaaggtctctggtaactctcgaacctactggtacctcgatatctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggttcagggcttcttccc +20642 JY8QFUQ01CXWBJ productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 973 94.06 206/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [2.17.38.11] CAKDLFQVSTTYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'GC' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggGCaagggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccAaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctctaggagcacctccgagagcacacgcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggctgtcgtggaact +20643 JY8QFUQ01ADDA1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20644 JY8QFUQ01BC8WA No results +20645 JY8QFUQ01AG7C2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV## out-of-frame - tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaagggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20646 JY8QFUQ01BIWAX No results +20647 JY8QFUQ01ADG4G unproductive Homsap IGHV3-30*01 F 874 89.04 195/219 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [2.17.38.11] CARGTMLRGSHQSE#YGLDVW out-of-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcgggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20648 JY8QFUQ01DC3JM unproductive Homsap IGHV3-7*02 F (see comment) 734 82.11 179/218 nt 81.65 178/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARLKGPDTS##FYFDLW out-of-frame + Low V-REGION identity (82,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'AGG' (3 nucleotides at position 60 to 62 in the user submitted sequence), (do not cause frameshift); cctctggattcgtctttactaatcattggatgagttgggtccgccaggccacaggggaaAGGgggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggcctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgcccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +20649 JY8QFUQ01ASHCC productive (see comment) Homsap IGHV3-11*01 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20650 JY8QFUQ01A4T8J unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 769 83.8 181/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20651 JY8QFUQ01AZKRJ productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20652 JY8QFUQ01BO2MF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) cctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20653 JY8QFUQ01BYBLN No results +20654 JY8QFUQ01CUOJE unproductive Homsap IGHV3-7*01 F 833 87.16 190/218 nt 86.7 189/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKARIYFYGSGSYSLFDY## out-of-frame + in FR3-IMGT at codon 74 of V-REGION: 'GC' (2 nucleotides at position 128 to 129 in the user submitted sequence), (cause frameshift); cgtctggattctccttcagcaattatgccatccactgggtccgccaggctcccgggaaggtgctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggGCccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctgtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20655 JY8QFUQ01CE09T unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 123 50.95 107/210 nt 8 8 X 8.8.X [1.17.35.X] null - No rearrangement found cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20656 JY8QFUQ01DSA5W productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'GT' (2 nucleotides at position 9 to 10 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'TG' (2 nucleotides at position 95 to 96 in the user submitted sequence), (cause frameshift); cctctggaGTtcagccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatTGgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20657 JY8QFUQ01CN0FC productive Homsap IGHV4-61*02 F 974 93.67 207/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSAPWNDHW in-frame + tctctggtggctccatcagcagcggttattactactggagctggatccggcagcccgccggggagggactggagtgggttgggcgtatctctgccagtggggacaccaactacaacccctccctcaagagtcgagtcaccatatcagtgaacacgtccaagaaccagttctccttgaggctgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagacaaggggacagtagtgctccctggaatgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20658 JY8QFUQ01ADKPR unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +20659 JY8QFUQ01B3CG7 productive Homsap IGHV4-61*02 F 951 92.73 204/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame + ctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20660 JY8QFUQ01B315R productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 746 83.26 179/215 nt 82.79 178/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggaccggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20661 JY8QFUQ01COL8E productive Homsap IGHV4-61*01 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame - tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20662 JY8QFUQ01BZNNC unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 752 83.03 181/218 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD2-8*02 F 2 8 7 X 8.7.X [2.17.38.11] CAGEEMRTRDGGW#YGTDVW out-of-frame - Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctctgggtgggctccatgactctttattattggagttggatccggcagcccgcagggaaggggctggagtgggttgggtacatcgatcacgctgggagcgccaagtataacgcctcccttcagagtcgagtcaccatctcagtcgacgcgcccaagaatcagttctctctgaagttgaactctgtgactgctgcggacacggccgtttattactgtgcgggagaagagatgcgaacgcgggacggggggtggctacggaacggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20663 JY8QFUQ01A6I3L productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame + ctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20664 JY8QFUQ01CG00S unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1045 97.72 214/219 nt 96.35 211/219 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKSGVGAT#YFDYW out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'TA' (2 nucleotides at position 19 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'TG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); gcctctggattcacatttTAggcagctatgccatgAagctgggtccgccaggctccagggaaTGgggcttggagtgggtctcagctattagtggtagtggtggtggcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagtcaggggtgggagctacaactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20665 JY8QFUQ01B1UHR productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [2.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift); gcctctggattcatcttcagtagctactggatgGcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtactaatacgggggggactagcacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20666 JY8QFUQ01AOYON unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F 896 89.95 197/219 nt 89.04 195/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 6 X 10.6.X [1.17.38.X] null - stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 44 of V-REGION: 'CA' (2 nucleotides at position 51 to 52 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) ctctggtgactccatgagcggtagtagtgactcctgggactggatccggcCAgtcccccagggaaggggctggagtggattgggagcacnattctagtggggccacttactacagcccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaagcaattctccctgaaactgacctctgtgaccgccgcagacacggcggtgtattactgtgcgagacatctgatttactactttcacttctgggggccagggaacccctggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20667 JY8QFUQ01ABCV4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20668 JY8QFUQ01A6L65 productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcagg +20669 JY8QFUQ01BPIG0 No results +20670 JY8QFUQ01BUZWP unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CACYFR**WF#FDYW out-of-frame + stop codons ttctggatacgtctttccctcctactggatcgcctgggtgcgccagatgcccggtaaaggcctggagtggctgggaaccatctatcccggcgactctgacaccacatacagcccgtcattccaaggccaggtcaccatgtcagtcgacacgtccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacagcgccatttactattgtgcgtgttattttcgatagtaatggtttctttgactactggggccagggaaccccaggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccttggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20671 JY8QFUQ01ALCBS productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 996 95.0 209/220 nt 94.09 207/220 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 9 7 14 9.7.14 [2.17.38.11] CARGEMTAEYYFDYWG in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); tgtctctggtggctccatcagcagtgttCaactggtggagttgggtccgccagcccccagggaaggggctggagtggaTttggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactgggggccagggaagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +20672 JY8QFUQ01A4LR9 productive (see comment) Homsap IGHV4-61*02 F 987 94.55 208/220 nt 93.64 206/220 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.37.11] CATVARRGAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 96 of V-REGION: 1 nucleotides (from position 195 in the user submitted sequence), (cause frameshift) tctctggtgggtGccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgaccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20673 JY8QFUQ01DIK16 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 967 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtCagtgactggatgtactgggtccgccaagctccagggaaggGggctggtntgggtctcacgtattaatggtaatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20674 JY8QFUQ01DGHAU productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 2 8 7 19 8.7.19 [1.17.38.11] CARSSDYLWGSYRYPYYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagttacttctggagttggatccggcagcCccccagggaagggactggagtggattggatatgtctattacagtggaagtaccaagtataatccttccctcgaaagtcgagtcaccatatcattagacacgcccaacaaccagttctccctgagcctgacctatgtcaccgctgcggacacggccatatactactgtgcgagaagctctgattacctttgggggagttatcgttatccctactacttcgactactggagccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20675 JY8QFUQ01BKOTH productive Homsap IGHV4-30-2*02 F, or Homsap IGHV4-55*06 P or Homsap IGHV4-59*01 F or Homsap IGHV4-59*02 F or Homsap IGHV4-59*03 F or Homsap IGHV4-59*07 F or Homsap IGHV4-59*09 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*03 F or Homsap IGHV4-61*07 F or Homsap IGHV4-61*08 F 162 94.59 35/37 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 X X 12 X.X.12 [X.X.12.11] CARAPGWMNPFDFW in-frame - ctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20676 JY8QFUQ01BK2YW No results +20677 JY8QFUQ01AOV8Y unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD1-7*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDCDSGECNFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggattcagcttcagtacctataacatgaactgggcccgccaggctccagGggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20678 JY8QFUQ01B9DAH productive Homsap IGHV4-4*07 F (see comment) 862 89.67 191/213 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-22*01 F 2 10 7 22 10.7.22 [1.17.38.11] CARERAYDRNGFYYANRHNWLDTW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01B9DAH ; 8 AA in Homsap_IGHV4-4*07) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggtgcctccatcacatttggcagttactactggaattggatccggcagcccgccgggaagggactggagtgggtaggacgtatctatgcaagtgggaccacccattccaacccctctctcgagactcgagtcatcatgtcactagacacgtccaacaaccagatctccctgaagctgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagagaaagggcctatgatagaaatggcttttactacgcgaaccgccacaactggctggacacctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20679 JY8QFUQ01BYDJU No results +20680 JY8QFUQ01A939N unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAGHLLGDP#FDYW out-of-frame - stop codons in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift); ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatctcggtgactctgacaccagaCtacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgaccctttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20681 JY8QFUQ01BU2ZW productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactca +20682 JY8QFUQ01CSC73 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20683 JY8QFUQ01AFH8P productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20684 JY8QFUQ01BPW7W unknown (see comment) Homsap IGHV4-4*08 F 146 53.71 94/175 nt 8 7 X 8.7.X [9.17.17.X] null - No rearrangement found stop codons gaccctgtccctcacctgcgatgtctctggtggctccatgactggttactactggagttggatccggcggccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +20685 JY8QFUQ01BWMMI productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 794 84.62 187/221 nt 83.26 184/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 10 15 8.10.15 [1.16.38.11] CTTDSFHIAVHGVFDFW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 32 in the user submitted sequence), (cause frameshift) tctgcattcatgttcaacaaagcctggatgaattggtccgccaggctccaggAaaagggactggagtgggttggccgtattaaaagtaacggcgacggtgcgacagtcgactacgctgcacCccgtgaaaggccgattcaccatctcaagagatgattcacagaataccctcttcttacaaatgagcagcctgaaagccgaggacacagccgtctattattgtaccacagatagcttccatattgcagtgcatggcgtctttgacttctggggccagggagccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcctcttccccca +20686 JY8QFUQ01AF4Q3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); catctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggGggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcancgcctgcctggtccagggcttcttccc +20687 JY8QFUQ01DM0CT No results +20688 JY8QFUQ01BWLFO No results +20689 JY8QFUQ01ABKIU No results +20690 JY8QFUQ01C02DF No results +20691 JY8QFUQ01B6PUH productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-48*04 F 621 99.21 126/127 nt 98.43 125/127 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 X 22 8.X.22 [1.6.26.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 91 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20692 JY8QFUQ01BBB3H productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20693 JY8QFUQ01CNCGL unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 101 95.45 21/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggattcaccttaagtga +20694 JY8QFUQ01AVX5J unproductive (see comment) Homsap IGHV4-61*01 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD1-26*01 F 3 10 7 X 10.7.X [1.17.38.11] CARGGPVGPTGI*SG#W out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 67 of V-REGION: 'TATAATCCCCTG' (12 nucleotides at position 111 to 122 in the user submitted sequence), (do not cause frameshift); tctctggtggctccgtcagcagagatatttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatgtatcacagagggaacactaagTATAATCCCCTGtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtccggtggggcctactggaatttgatccgggactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +20695 JY8QFUQ01BFYAE productive Homsap IGHV3-9*01 F 882 89.86 195/217 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDVTSESHFFALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctcgggattcaagtttgatgaatatgccatgcactgggtccggcgagttccagggaggggcctggagtgggtctcagttataagttgggatggtgatgacatcgcctatgcggactctgtgaagggccgattcagcatctccagagacaacgccaagaactccctgtacctggaaatgagcagtctgagagttgaggacacggccttctattactgtgcaaaggatgtcacatctgaaagtcatttcttcgctttggacgtctggggccaagggaccgcggtcaacgtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20696 JY8QFUQ01CGUXU unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.89 192/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20697 JY8QFUQ01DA1JV unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*09 F or Homsap IGHV3-30*10 F 869 88.99 194/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-12*01 F 2 8 8 X 8.8.X [1.17.38.11] CAREHDTGVATRYFDY## out-of-frame + in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); cctctggattcgccttcagtctgtatcctatgcactggGgtccgccaggctccaggcaaggggActagagtgggtggGcacttatctcctctgatggaagtgataagttttcctcagactccgtgaagggccgattcgccatctccagagacaattccaagaacacggtctatctacaagtggacagcctgagaactgaggacacggctatgtatttctgtgcgagagagcacgacacgggagtggcgacgaggtattttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +20698 JY8QFUQ01AKKV6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVKDISRSGCFEYW in-frame + cctctggattccagtttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20699 JY8QFUQ01B1B92 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDTITMGGDVAPLFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtaactatgacatgggctGgggtccgccaggctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +20700 JY8QFUQ01BO2CM productive Homsap IGHV3-33*04 F (see comment) 698 80.28 175/218 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame - Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release catttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20701 JY8QFUQ01CQKI9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-25*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDLLGIAPAGHSLDHW in-frame + ctctggattcacctttggcaactatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagaggtgaccacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaggaacacactgtttctgcaaatgaatagcctgggagtcgaggacacgaccgtatattactgtgcgaaggatcttctagggattgcgccggcgggccattcccttgaccactggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20702 JY8QFUQ01AFCWF productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20703 JY8QFUQ01C28XA productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 3 8 8 20 8.8.20 [1.17.38.11] CARLPYIVVLTNIISPTYFDFW in-frame - ctggagtacagttttaccagttactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctgctgactctgataccagatacagcccgtccttccaaggccaggtcagcatctcagccgacaagtccatcgacaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgcggctgccatatattgtggtgctgactaatataatctccccaacctactttgacttctggggccagggaacccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20704 JY8QFUQ01BCVP2 productive (see comment) Homsap IGHV4-61*01 F 988 94.14 209/222 nt 93.69 208/222 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [2.17.38.11] CARGGSGGAYWNLIRDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 67 of V-REGION: 'TATAATCCCCTG' (12 nucleotides at position 112 to 123 in the user submitted sequence), (do not cause frameshift); gtctctggtggctccgtcagcagagatatttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatgtatcacagagggaacactaagTATAATCCCCTGtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtgggtccggtggggcctactggaatttgatccgggactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20705 JY8QFUQ01AR7B6 productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + cctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20706 JY8QFUQ01CPGWX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARGHSYYVSSGPDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); agcctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgCcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20707 JY8QFUQ01CPE55 productive (see comment) Homsap IGHV4-4*07 F (see comment) 750 83.64 179/214 nt 82.24 176/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'GCGT' (4 nucleotides at position 79 to 82 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'CT' (2 nucleotides at position 213 to 214 in the user submitted sequence), (cause frameshift); ctctggtacctccatcagcacttactattggagttCggttccggcagcccgccgagaagggactggagtggaattgggGCGTatctctgtctttgcaaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtaCTtttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20708 JY8QFUQ01ABP0U productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-3*01 F 1 8 8 20 8.8.20 [0.17.38.11] CARDHRSGALEWSHHYHGMDVW in-frame - tggttacatcttcacccactatggtatcaactgggtgcgccaggcccctggacaagggcttgagtggatgggatggatcagcgcctacagtggtaacacaaagtatgcacagaaggtccagggcagagtcaccatgaccacagacacttccacgagtacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagatcacagaagcggggctttggagtggtctcaccactaccacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20709 JY8QFUQ01B6VRF No results +20710 JY8QFUQ01ALKG8 No results +20711 JY8QFUQ01DPIF7 unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDSRHSASGSYSDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactgggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20712 JY8QFUQ01AB9MS productive (see comment) Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt 81.19 177/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggGggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20713 JY8QFUQ01C4HVK productive (see comment) Homsap IGHV3-66*02 F 894 91.12 195/214 nt 90.65 194/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcagtagcagcttcatgacttGgggtccgcctggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaact +20714 JY8QFUQ01ALAOB productive (see comment) Homsap IGHV1-3*01 F 858 89.25 191/214 nt 88.79 190/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); tggatacaGccttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20715 JY8QFUQ01CV8HV unproductive Homsap IGHV1-2*02 F 831 87.85 188/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [0.17.38.11] CARDGISMTLVRGVRPFDY## out-of-frame + tggatacaccttcatcggccattatatacattgggtgcgacaggcccctggacaagggcttgaatgggtggggtggatcaaccctaacagtggtgttacaaactatgcacagcagtttcaggacagggtcaccatgaccgtcgacacgtccatcagcactgcctacatggacctcaaaagtctaaagtctgacgacacggccatctattactgtgcgagagacggaataagtatgactctggttcggggagttaggcccttcgactactgggggccagggaaccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +20716 JY8QFUQ01BRNII productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 803 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtctctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaac +20717 JY8QFUQ01BOFAK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20718 JY8QFUQ01AYAP4 productive (see comment) Homsap IGHV3-7*01 F 933 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [2.17.38.11] CARGSYWHYDTFGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'AA' (2 nucleotides at position 85 to 86 in the user submitted sequence), (cause frameshift); agcctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacatAAaaatcaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +20719 JY8QFUQ01B6H5N productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaaggacccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20720 JY8QFUQ01AGHGS productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20721 JY8QFUQ01DG6CB productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 145 78.72 37/47 nt 8 8 5 8.8.5 [1.17.38.11] CAHTAFW in-frame - ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaatcccataaacactctttttctgcaaatgaacagcctcagagtcgaagattcgggtgtctatttttgtgcacacactgccttctggggccggggatcccgggtcaccgtctcctccgcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20722 JY8QFUQ01AA7HK unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20723 JY8QFUQ01CKO8I productive (see comment) Homsap IGHV4-4*07 F 1061 99.53 214/215 nt 98.6 212/215 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD4-11*01 ORF 2 8 7 13 8.7.13 [1.17.38.11] CARDFSNRGWYFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagtttctactggagctggatccggcagcccgccgggaagggactggagtggattggGgcgtatctataccagtgGggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +20724 JY8QFUQ01B63YT No results +20725 JY8QFUQ01BYXTT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20726 JY8QFUQ01A7TR1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20727 JY8QFUQ01BJY9W No results +20728 JY8QFUQ01B2LLS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVKEDHDSGLRVLLEW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20729 JY8QFUQ01CEEBP No results +20730 JY8QFUQ01A990T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20731 JY8QFUQ01B9QX0 productive (see comment) Homsap IGHV3-7*01 F 1021 97.22 210/216 nt 96.76 209/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 7 8 11 7.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtactattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20732 JY8QFUQ01B63RG unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 196 76.47 52/68 nt 8 X X 8.X.X [1.13.X.X] null - No rearrangement found gctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggcttcttccccca +20733 JY8QFUQ01B9IRL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20734 JY8QFUQ01AAS9C productive Homsap IGHV2-5*02 F 1134 96.31 235/244 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-17*01 F 3 10 7 13 10.7.13 [9.17.38.11] CAHFSVTTPYGMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gaccctcacgctgacctgcaccttctctgggttctcactcaccactactggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcagtcattttttgggatgatgatgagcgccacagcccatctctgaggagaaggctcaccatcaccaaggacatctccaaaaaccaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacttttcggtgactaccccatatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20735 JY8QFUQ01B8O0E productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 256 90.32 56/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20736 JY8QFUQ01ABTRQ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 775 85.71 180/210 nt 85.24 179/210 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD1-26*01 F 2 7 8 X 7.8.X [X.17.38.11] CATRNKMGISTPVDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); ctcaacattggcaactatgacatgacctgggtccgccaggctcctgggaaggggctggagtgggtctcaagtattggaactactgagggtagctcatattatgcagactccgtgaagggccggttcaccatctccagagacaactcccagactacgctgTtttttggagatgagcagcctgagagacgaggacacggccgtatattactgtgcgacaaggaataaaatgggaattagtacgcctgttgactactgggggccagggaaccctagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20737 JY8QFUQ01DNAB2 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 853 86.94 193/222 nt 86.49 192/222 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD2-21*01 F 2 8 10 8 8.10.8 [1.17.38.11] CTSNSWLDRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); tctggattcaCcatttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggttggccgtattaaaaaggcagttgatggtgggccaacagactacgctgcacccgtcaaaggcagattcaccatctcaagagatgattcaaaaaatacgttgtatttgcaaatgaacagcctgaaaagcgacgacacaggcatttattactgcacctcgaattcctggctcgaccgctggggccagggaacccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20738 JY8QFUQ01BQJ6P No results +20739 JY8QFUQ01BX764 productive (see comment) Homsap IGHV1-2*02 F 913 91.67 198/216 nt 90.74 196/216 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDWGGKYAPLDNW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); tctggatacatcttcaccggctactatttgcactgggtgcgacaggAcccctggacAaagggcttgagtggatgggatacatcgacccttacactggtgacacaaattatgcacagaggtttcagggcagggtctccatgaccagggacacgtccatcagtacagcctacatggaactgaacaggctgatgtctgacgacacggccatgttttactgtgcgagagattggggtgggaagtacgcaccgctagacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +20740 JY8QFUQ01A8FGD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 133 74.0 37/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaacccaggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20741 JY8QFUQ01CGUYG productive Homsap IGHV3-72*01 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame - cctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20742 JY8QFUQ01CECEB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 777 85.05 182/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [0.17.38.11] CARDAGNTWPNYFDHW in-frame - tggattcagctttttcaattatggcatgaactgggtccgccaggctccagggagggggctggagtgggtcgcatttattagcggtgctggtgaaaatacttactacgcagactccgtgaagggccgattcgccatctccagagacgattcgagggacacactgtatctccaaatgagcagcctgagagccgaggactcggccctctattattgtgcgcgagatgcgggcaacacctggcccaactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20743 JY8QFUQ01C2XVI unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 897 90.0 198/220 nt 89.55 197/220 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [2.17.38.11] CVSDLAGQKGS## out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); agcctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaAaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggaagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagctctgcagcaccacgccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20744 JY8QFUQ01BF03M No results +20745 JY8QFUQ01APHY3 unknown (see comment) Homsap IGHV1-2*02 F (see comment) 777 84.58 181/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (84,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tggatacatcttcaccggctactatttgcactgggtgcgacaggcccctggacaagggcttgagtggatgggatacatcgacccttacactggtgacacaaattatgcacagaggtttcagggcagggtctccatgaccagggacacgtccatcagtacagcctacatggaactgaacagcctgacagtcgcggacgcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20746 JY8QFUQ01CB4YK No results +20747 JY8QFUQ01AXR1M productive (see comment) Homsap IGHV3-48*01 F (see comment) 754 84.04 179/213 nt 82.63 176/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 82 in the user submitted sequence), (do not cause frameshift) tctggattcaccttcggGaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtGgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20748 JY8QFUQ01BIE6S productive (see comment) Homsap IGHV3-7*02 F 860 88.07 192/218 nt 86.24 188/218 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'GG' (2 nucleotides at position 61 to 62 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'TG' (2 nucleotides at position 76 to 77 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'AG' (2 nucleotides at position 130 to 131 in the user submitted sequence), (cause frameshift); cctctggattcacctctcctagatactggatgaattgggtccgccaggcttccggggaagGGggctggagtggggTGgccaaacataaagcaagacggaagtgagGaaaaactttgtggactctgtgaaAGgggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20749 JY8QFUQ01AZRH6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20750 JY8QFUQ01BBRQO No results +20751 JY8QFUQ01BV511 unknown (see comment) Homsap IGHV3-71*03 P, or Homsap IGHV3-73*01 F or Homsap IGHV3-73*02 F 92 90.91 20/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggtttcacgttcagtgg +20752 JY8QFUQ01BVVPS productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVRGRIVSVGMAGWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); tctctggattcaccttcagGgaactattggatgcactgggtccgccaagctccagggaaggGggctggagtgggtctcacgtatcaatggcgacggaagtagcacaagctacgcggactccgtgaagggccgattcaccatctccagagacaacgccgagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacagccgtatatttttgtgtaagaggccgtatagtgtcagttggtatggcaggctggttcgacccctggggccagggaacgcaggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20753 JY8QFUQ01DLFRL No results +20754 JY8QFUQ01BT0O2 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20755 JY8QFUQ01DP6L3 productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20756 JY8QFUQ01AL2JX unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARKRVPGGDFLW#DYW out-of-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccgggggggactttttatgggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20757 JY8QFUQ01AMN6K productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 860 88.53 193/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'CG' (2 nucleotides at position 99 to 100 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); gttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctCGaggcccagatacagcccgtccttccCaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20758 JY8QFUQ01CHCOL productive Homsap IGHV1-8*01 F 912 92.06 197/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [0.17.38.11] CAREGLLGSLGSW in-frame - aggatacaccttcatcagttatgatatcaattgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaacagcggtaacacagggtttgcacagaggttccagggcagagtaaccatgaccaggaacatctccataaacacggcctacatggagctgaccaacctgacatctgatgacacggccgtatattattgtgcgagagaaggtctattgggcagcctaggatcttggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20759 JY8QFUQ01CMO81 No results +20760 JY8QFUQ01AYINE productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20761 JY8QFUQ01B7FDU unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 129 62.82 49/78 nt 8 X X 8.X.X [1.17.X.X] null - No rearrangement found tctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20762 JY8QFUQ01CJS0O productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD6-25*01 F 2 8 7 15 8.7.15 [1.17.37.11] CTRELRMAAARDGVDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 100 of V-REGION: 1 nucleotides (from position 203 in the user submitted sequence), (cause frameshift) cctctgggttcgccgtcagtagcaagttcatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatcctgatgggactacacactatggagactccgtgaggggccgattcaccacctccagagacaattctaagaacatcttggatcttcaaatgaacagcctgagagccgaggacacggcgttacttattgtacgagagaacttaggatggctgcggcgcgtgatggtgttgacatctggggccaaggcacaatggtcaccgtctcttcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20763 JY8QFUQ01BCFRZ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggGtgtgggtgtcacgtagtaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20764 JY8QFUQ01B44NZ No results +20765 JY8QFUQ01A9TKS No results +20766 JY8QFUQ01CBZJD No results +20767 JY8QFUQ01DICV1 productive (see comment) Homsap IGHV3-7*01 F 1035 97.7 212/217 nt 97.24 211/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); ctctggattcaggtttagcatctattGggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20768 JY8QFUQ01DEEMH unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 150 56.52 78/138 nt 10 7 X 10.7.X [1.17.10.X] null + No rearrangement found stop codons tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +20769 JY8QFUQ01AQXYS No results +20770 JY8QFUQ01CSABC productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtccgtggaactcag +20771 JY8QFUQ01AN7G1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame - ctctggattcaccttcagtcgctatagcatgaactggatccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20772 JY8QFUQ01DPW4S No results +20773 JY8QFUQ01BAHK0 productive Homsap IGHV3-74*03 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRDSDSSASYFAHW in-frame + gcctctggattcaccttcagtagctactggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +20774 JY8QFUQ01AIINB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-33*02 F or Homsap IGHV3-53*01 F or Homsap IGHV3-53*02 F or Homsap IGHV3-53*03 F (see comment) 290 78.95 75/95 nt 77.89 74/95 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 X X 12 X.X.12 [X.X.31.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (78,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift); tgtctggattcaccatctccagagacaattccaGgggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20775 JY8QFUQ01DQG8Q unproductive Homsap IGHV4-61*02 F 907 90.09 200/222 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD2-21*01 F 3 10 7 X 10.7.X [2.17.38.11] CAREKGSDPS#NWFDPW out-of-frame + gtctctggtgactccatcaccagtggtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaatccctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagagaaaaaggtagtgatccgtcccaactggttcgacccctggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20776 JY8QFUQ01A0WDV productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20777 JY8QFUQ01COIIN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20778 JY8QFUQ01AD6S1 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 169 76.27 45/59 nt 8 X X 8.X.X [1.10.X.X] null + No rearrangement found ctctggattcaacttcagaacctattggatgggctgggtccgccaggcttcttccccca +20779 JY8QFUQ01AOP21 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggGggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20780 JY8QFUQ01DIP8G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 919 91.32 200/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAKEIAVSGEGALDFW in-frame + gcctctggattcaccttcagtaactatagcatgagctgggtccgccaggctccagggaaggggccggagtgggtctcagctattactggtcttgatggtagaacattctacgcagactccgtgaagggccgtttctccatctccagagacaattccaagaacacgttgtatttgggaatgaacagcctgagagccgaggacacggccgtatattattgtgcgaaagagatagcagtgagtggtgagggggcgttggacttctggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctttcccca +20781 JY8QFUQ01BTQ4G unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 810 94.44 170/180 nt 8 8 X 8.8.X [2.17.25.X] null + No rearrangement found gcctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatg +20782 JY8QFUQ01CK6Q5 productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame - Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20783 JY8QFUQ01APDWZ No results +20784 JY8QFUQ01A4XDT productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt 99.54 216/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagGggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20785 JY8QFUQ01AUC9Z productive Homsap IGHV3-9*01 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD1-7*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKDKWNSPLYFFDYW in-frame + tctggattcagttttgatgattatgccatgcactgggtccggcaagttccagggaagggcctggagtggctctcagggatcagttggaatagtgggagcaaaggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagctgaggacacggccttttattactgtgcaaaagataagtggaactcccccctctacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +20786 JY8QFUQ01CHR57 unproductive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDQVTEDY# out-of-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactgggccagggaaccctggtcagtgtctcctccagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20787 JY8QFUQ01B6VLM productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame + gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20788 JY8QFUQ01B3AX2 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-9*01 F 2 8 8 21 8.8.21 [1.17.38.11] CVREGIEYYEISTGQYYYDMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); cctctggattcacAttttagcggctatggcatgagctgggtccgccaggctgcagggaaggggctggaatgggtctcatttattagtggtaagagcggcaacatatactatgcagaccccgtgaagggccggttcaccatctccagagacaactccaagaataggctcttcctgcagatgaacagcctgagagtcgaggacacggccaaatattactgtgtgagagagggcatagagtattacgaaatctcgactggacagtactactacgatatggacgtctggggccaggggaccacggtcaccgtcctctctgcatcccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20789 JY8QFUQ01CYMCX productive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20790 JY8QFUQ01A9YO5 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 875 88.24 195/221 nt 87.78 194/221 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARQRYYESDGQTW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaccggaagtagttattattggggctggattcgccagTcccccagggaaggggctggagtggattggaagtatgtattacactgggagcaccgactacaacccgtccctcaagagtcgggtcacgatatccgcagacaagtcgaagagccaggtctacctgaagttggactctgtgaccgccgcagacacaggtgtttattactgcgcgagacaaaggtactatgaaagtgatggccaaacctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20791 JY8QFUQ01BNISQ productive Homsap IGHV4-4*07 F 809 86.51 186/215 nt Homsap IGHJ3*02 F 160 80.0 40/50 nt Homsap IGHD3-22*01 F 2 8 7 11 8.7.11 [1.17.38.11] CAGRNGNLAFNIW in-frame - tatctggtggttcgatcgtcagttactactggagttggatccggcagtccgccgggaagggactggagtggattgggcgcatctactccaatggagatacgagctacaatccctccctcaagggtcgagtcaccatgtcagtagacccttccaacaaccagttctccctgaaattgacttctgtgaccgccgcggacacggccatatattactgtgcgggaagaaatggaaatttggccttcaatatttggggccaagggacaaatgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20792 JY8QFUQ01BFOH6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - tctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20793 JY8QFUQ01CDUMU unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 394 75.71 106/140 nt 8 8 X 8.8.X [2.17.11.X] null - No rearrangement found Low V-REGION identity (75,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20794 JY8QFUQ01B1UM4 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F (see comment) 644 77.06 168/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (77,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctcgggattcaacttcaagtccaacaccatgaattgggtccgccaggctccagggaaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20795 JY8QFUQ01B3E28 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1031 97.25 212/218 nt 96.79 211/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKELGEGPDWELLP#YFHYW out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacgttcagtggctatggcatgcactgggtccgccaggctccaggcaaggGggctggagtgggtggcagttgtatcatatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctctctctgcaaatgaacagcctgagagctgaggacacggctgtatattactgtgcgaaagaattgggggagggccctgactgggaactactaccagtactttcactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggttcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccc +20796 JY8QFUQ01A5V9M productive Homsap IGHV3-48*02 F 864 88.94 193/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD6-6*01 F 1 8 8 20 8.8.20 [1.17.38.11] CARDDSRLWSSSFNHYFAMDVW in-frame + ctctggattcacctttagtgattatagaatgaattgggtccgccaggctccagggatggggctggaatgggttgcacacattagtaccagtggtagtagtatatactatgcagactctgtgaagggccgattcaccgtctccagagacgatgccaagaattcactttttctgcaaatggacagcctgagagacgacgacacggctgtatattactgtgcgagagacgattcacggctgtggagctcgtcatttaaccactatttcgctatggacgtctggggccaagggaccaccgtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc +20797 JY8QFUQ01CKFRG productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20798 JY8QFUQ01B0ZV3 unproductive (see comment) Homsap IGHV3-66*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F (see comment) 123 72.92 35/48 nt Homsap IGHD6-13*01 F 3 8 7 X 8.7.X [1.16.38.11] CARDSPYSSGWSDGF*CL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift) cctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctgagtgggtctcaattatttatatcagtggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaagaacacggtgtatcttcagatgaacagtctgagagctgaggacacggctgtgtattactgtgcgagagatagtccatatagcagcggctggtctgatggcttttgatgtctgggggccaagggacaatggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +20799 JY8QFUQ01B76KB productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 863 89.3 192/215 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [0.17.38.11] CACGHMRDGYDVW in-frame + ctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20800 JY8QFUQ01ABKJ7 productive Homsap IGHV3-11*01 F 883 89.5 196/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARDDSCSGGSCYEYW in-frame - acctctggattcagtttcagtgactactacatgagttggatccgccaggctccagggagggggctggagtgggtttcatatattgatagcggtggtaccgccatgtactactcagactccgtgaagggccgattcaccatctccagggacaacgccaagaagtcactgtttctgcaaatgagtagcctgagagccgaagacacggccgtgtactattgtgcgagagatgactcttgtagtggtggtagctgttacgaatactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20801 JY8QFUQ01BUMPR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDTITMGGDVAPLFDYW in-frame + ctctggattcacctttagtaactatgacatgggctgggtccgccaggctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgtctgcctggtccagggcttcttccctc +20802 JY8QFUQ01DCQZ3 No results +20803 JY8QFUQ01BW4UM unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.37.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT, from codon 77 of V-REGION: 1 nucleotides (from position 137 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcttgcattagaagtagtggtgatgacgtattctacgcggactcagtgaagggccgattcacatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgtgcgagagatgttccgggtgacaacgttggacgtactgggccagggcggaaccccggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20804 JY8QFUQ01BN5AH productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + tctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20805 JY8QFUQ01A0EXZ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 891 89.86 195/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20806 JY8QFUQ01BX863 unproductive Homsap IGHV4-39*03 F 929 91.36 201/220 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSITLTVVVMNDAFDV## out-of-frame + tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctgggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20807 JY8QFUQ01CLWE2 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20808 JY8QFUQ01CXKO7 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggGggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20809 JY8QFUQ01DMZC9 productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame - ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20810 JY8QFUQ01CZ6QA productive Homsap IGHV3-11*01 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - gcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +20811 JY8QFUQ01C7IHT No results +20812 JY8QFUQ01CCTAQ No results +20813 JY8QFUQ01CIR3P productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20814 JY8QFUQ01ASHC2 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 896 90.37 197/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGEFYYETSGRRGFELL# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcactacctcctggatgcactgggtccgccaagctccagggaaggggctaatgtgggtctcacgtgtgaataaggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaccacgctgtacttggaaatgaacagtctgagagtcgaggacacggctatgtattattgtgcaagaggagaattttattatgaaactagtggtcgaaggggttttgaactactgggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20815 JY8QFUQ01BC283 productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 277 80.46 70/87 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.29.11] CVKDRKGSNWYYFENW in-frame - Low V-REGION identity (80,46% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +20816 JY8QFUQ01C21C9 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 760 83.8 181/216 nt 82.41 178/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); tctggatccagGtttcagtggcttTtggcgtgaactgggtccgccaggctccagggaaggggctggGaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagaaacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgctcggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20817 JY8QFUQ01CWOUE productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 830 88.21 187/212 nt 87.74 186/212 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 7 8 17 7.8.17 [X.17.38.11] CARDSGSSEYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); gattcagcttaagttcttatggcatgaactgggtccgccaggctccaTgggggggggctggagtgggtctcattcattaacagtattagtagttataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20818 JY8QFUQ01B22ZO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGG# out-of-frame + ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagcggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggccagggagccctggtctccgtctcctcagcatccccgaccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20819 JY8QFUQ01BWYJK No results +20820 JY8QFUQ01C2TGT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 951 92.73 204/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - agcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +20821 JY8QFUQ01AL2IL productive Homsap IGHV3-7*01 F 887 89.91 196/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + cctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20822 JY8QFUQ01B8TFF unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1105 100.0 222/222 nt 99.1 220/222 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [2.17.38.11] CARSRTFYGSANY## out-of-frame + in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagcagtagtagttactactgGgggctggatccgccagcCccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20823 JY8QFUQ01ABZLF productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20824 JY8QFUQ01BU904 No results +20825 JY8QFUQ01CGPJ4 productive Homsap IGHV3-7*03 F 855 88.48 192/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame - ctctggattcaccttcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +20826 JY8QFUQ01CVY0F productive (see comment) Homsap IGHV4-39*03 F 928 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 9 7 17 9.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) ctccggtggctccatcaacagtagaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20827 JY8QFUQ01DDL1C unproductive (see comment) Homsap IGHV3-7*01 F 1044 98.16 213/217 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDPYSSGRGHF*LL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtttctattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatccgtatagcagtggccgggggcacttttgactactggggccaggggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20828 JY8QFUQ01AEWIJ No results +20829 JY8QFUQ01C2YXQ No results +20830 JY8QFUQ01AIGW8 unproductive Homsap IGHV3-13*01 F 971 94.88 204/215 nt 93.95 202/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 X 8.7.X [1.17.38.11] CAEGRQK#YNWFDPW out-of-frame - in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); cctctggattcacgttcagtaattacgacatgcactgGggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaAagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20831 JY8QFUQ01A9S2H productive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 804 86.45 185/214 nt 85.98 184/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDYFDSW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccgactacttcatacactggctgcgacaggCcccctggacaacgacttgagtggatgggatggatcaaccctaagaatggtgacacaaagtatgcacagaactttcagggccgggtcaccatgaccagggacacgtccgtcagcaccatatatgtggaggtgagcagcctggaatctgacgacgcagccacttattactgtgcgagaggcttttatggtgactactttgactcctggggccagggagccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20832 JY8QFUQ01B8Q7B unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1115 100.0 224/224 nt 99.55 223/224 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFFGLL# out-of-frame + stop codons in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift); cttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccAaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggctacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20833 JY8QFUQ01A35C3 productive Homsap IGHV4-34*06 F (see comment) 701 80.84 173/214 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 14 8.7.14 [1.17.38.11] CSRGGQSAGWHSFEAW in-frame + Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tccatggtgggtccctcaggggttacccctggacctggatccgccacaccgcagagaagggactggagtggattggtcaaatcaatagtgatggaaggacaacctacaactcggccctcatgggtcgagtcaccatttcaacagacacatccaagaatcagttctcgctgactgtggtttctgttgtcgccgcggacacggcaatgtattattgttcgagaggaggccaaagtgctggctggcactcctttgaagcctggggccagggaacccaggtaatcgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20834 JY8QFUQ01BZF3U productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt 90.5 200/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 216 to 216 in the user submitted sequence), (cause frameshift); tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatTtcctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +20835 JY8QFUQ01CBS6J productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt 94.06 206/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDCDSGECNFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggccccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20836 JY8QFUQ01A1CTT productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt 91.71 199/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'CG' (2 nucleotides at position 75 to 76 in the user submitted sequence), (cause frameshift); ttctggaGtacacgtttatgaattactggatcggctgggtgcgccagatgcccgggAaaaggcctggagtggatCGggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +20837 JY8QFUQ01B1YVE No results +20838 JY8QFUQ01AU5W7 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 752 83.03 181/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CAMRFLWWS*VLPLS*QL# out-of-frame + stop codons Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctgggttcacattcagtaactactggatccactgggtccgccaagctccaggaaaggggctagagtgggtcgcacgtattaatgatgctggaaagcgtgccgacttcgcgactttcgtgaagggccgattctccatctcccgagacaacgccaagaacacagtgtatctggaaatgactagtctgagagtcgacgacacggctgtctatttttgtgcaatgcgatttttgtggtggtcctgagtgctacccttatcttgacaactgggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20839 JY8QFUQ01A9228 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactc +20840 JY8QFUQ01AZAAF unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1013 96.33 210/218 nt 95.87 209/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDRVYGGGRA##DHW out-of-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggaggggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20841 JY8QFUQ01C82LB No results +20842 JY8QFUQ01CF7WP productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1016 97.21 209/215 nt 95.35 205/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'T' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 81 of V-REGION: 'G' (1 nucleotides at position 147 to 147 in the user submitted sequence), (cause frameshift); ctggatacaccttcaccagctactatTttgcactgGggtgcgacaggCcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccaggGgacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcgaggggacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20843 JY8QFUQ01CLNZR productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 841 87.96 190/216 nt 87.5 189/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSGPSGYARYESMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 94 of V-REGION: 'T' (1 nucleotides at position 186 to 186 in the user submitted sequence), (cause frameshift); tctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacctTgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20844 JY8QFUQ01BZN3J productive (see comment) Homsap IGHV4-61*02 F 990 95.39 207/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*02 F 2 9 7 15 9.7.15 [1.17.38.11] CARAGKQDFWSGYSDDW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'GTG' (3 nucleotides at position 21 to 23 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 3 nucleotides (from position 23 in the user submitted sequence), (do not cause frameshift) ctctggtggctccatcggcaGTGgtagttattactggagctggatccggcagcccgccgggaagggactggaataccttgggcgtatctataccagtgggagcaccaactacaaccCcctccctcaagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgctgacacggccatttattactgtgcgagagcggggaaacaggatttttggagtggttattctgacgactggggccagggaaccctggtcatagtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20845 JY8QFUQ01COX06 No results +20846 JY8QFUQ01AE2VJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 775 84.02 184/219 nt Homsap IGHJ1*01 F 170 80.77 42/52 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CARPDGGNGWAAKYFQMW in-frame - Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctgggttctcgtttaatagttatggtatgacatggttccgccaggctccggggagggggctggagtgggtctcatctataactggaactgggggtaacgttttctacgcagacttcgtgcagggccggttcaccatctccagagacaattccgacaatatgttgtttctgcaaatgaacagcctgagagttgaggacacggccgtgtattactgtgcgagacctgacggaggcaatggctgggccgcaaagtactttcagatgtggggccagggcacccttctcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20847 JY8QFUQ01CGTHL productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.16.38.11] CARAPRTATLLDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccaggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20848 JY8QFUQ01AVOUX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctggggctgcctggtcaagggactacttcccccgaaccggtgacggtgtcgtggaactcagg +20849 JY8QFUQ01BC320 productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*03 F (see comment) 373 77.78 98/126 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 X 4 12 X.4.12 [X.X.38.11] CARGPVSGWYTDYW in-frame - Low V-REGION identity (77,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ggatacaccttcaccgtctactatctattctggggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20850 JY8QFUQ01BYZBL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDWSIGARFPQGAFDIW in-frame + cctctggattcacctttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctctttcattagtggtaatggtggtagcatagactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaatacgctgtatctgcaaatgaatagtctgagagccgaggacacggccgtctattactgtgcgaaagattggagtataggagcacgtttcccccaaggagcttttgatatctggggccaaggggaattggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20851 JY8QFUQ01C5RSZ productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame - ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20852 JY8QFUQ01B49G5 unproductive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDDDFWEW*T#FDPW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcagtcttaataactactggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaatataaaaaaagatggaagtgagaaatactatgtggactctgtgaagggccgtttcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagaggcgaggacacggctgtgtatcactgtgcgagagacgacgatttttgggaatggtaaacacttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20853 JY8QFUQ01B4YMU productive Homsap IGHV3-48*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARESTWEFTPDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcagtttcagtgactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagttctagtagtaccctatattatgcagactctgtgaagggccgattcaccgtctccagagacaatgacaagagttctctgtatctgcaaatgaccggcctgagagccgaagacacggcgacttattactgtgcgagagagtcgacgtgggaatttactcctgactcctggggcccggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20854 JY8QFUQ01BPQPP No results +20855 JY8QFUQ01CX3WO No results +20856 JY8QFUQ01A5W0Y No results +20857 JY8QFUQ01CH28M productive (see comment) Homsap IGHV3-48*01 F 929 91.4 202/221 nt 90.5 200/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 15 8.8.15 [2.17.38.11] CAKVGSMNIEASPPDDW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); ccgtctctggattcagcttcagttcctatagcatgagctgGggtccgccaggctccggGggaaggggctggagtgggtctcatatattagtagtagtggtaggaccatctactacgctgactccgtgaagggccgattcaccatgtccagagacaatgccaagaattcactgtatctacaaatgaacagcctgagagccgaggacacggccgtctattactgtgcgaaagttggcagcatgaatatcgaggcgagccctcctgacgactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20858 JY8QFUQ01AGRAL productive Homsap IGHV3-33*05 F 945 92.63 201/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - gtctggattcaccttcagtagctacggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacactgtatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20859 JY8QFUQ01C1WE0 No results +20860 JY8QFUQ01CLNGA No results +20861 JY8QFUQ01C1ROT unproductive Homsap IGHV3-11*01 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRRVWGYSYGSVSYYFEY## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 69 of V-REGION: 'A' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggcagtgctactaccatatcctacgcaAgactctgtgaagggccgattcaccatctccagggacaacgccaaaaactcactttatctgcaaatggacagcctgagagccgaggacacggccatatattactgtgtgaggcgggtgtggggatacagttatggttccgtttcgtactactttgaatactggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20862 JY8QFUQ01AKZ01 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20863 JY8QFUQ01CLW3Q productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 872 87.95 197/224 nt 87.5 196/224 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 10 14 8.10.14 [1.17.38.11] CAREGYISTWYLFDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'C' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); ctatggggttcacgtttggtgattatcctttaagctggttccCgccaggctccaggcaagaggctggagtgggtaggtttcattagacccagtgcttatggtgggacaagagaatacgccccgtctatgaaaggccgattctccatctcgagagatgactccaaaagtgtcgcctatctgcaaatgaacagcctgagaacggaggacacagccgtatatttctgtgctagagagggttacatcagcacctggtacctctttgactcttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20864 JY8QFUQ01C3753 unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 804 85.98 184/214 nt 8 8 X 8.8.X [0.17.38.X] null - No rearrangement found tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20865 JY8QFUQ01AYAO5 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CARRSGRDGG#WFDSW out-of-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcatctttgccgactatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtcgcagatattaatggaagaggtgctgccgcacactacgcagactccgtgacgggccgcttcaccctctacaaagacggttccaagaatacgatgtatctgcaaatgaggaccctgagagacgacgacacggccaaatattactgtgcgagacgaagtgggcgtgatgggggcctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20866 JY8QFUQ01DFYHU No results +20867 JY8QFUQ01B4IIY unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 959 93.58 204/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [1.17.38.11] CVKDLLGGDPF#W out-of-frame - Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtcgctatggcttgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcagatgatgggaagaataaattctatacagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgatgtttgtgcaactgaacagtctgagagctgaggacacggctgtgtattactgtgtgaaagacctactaggtggtgacccctttttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20868 JY8QFUQ01BJRF9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARDGEWEMLDHW in-frame + ctccggattcaccttcagtaggtattggatgtattgggtccgccaagctccaggcaaggggctggtgtgggtctcacgcattaaaagtgatgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacatatttttgtgcaagagacggggagtgggagatgcttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagctctgcagccacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20869 JY8QFUQ01CDXDA productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 931 92.59 200/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 21 8.8.21 [1.17.38.11] CVRVGAPYYDFWSGYQTNWFDPW in-frame - tctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgctagtactacttccatacactatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggcgccatattacgatttctggagtggctatcagactaactggttcgacccctggggccagggaactctggtcaccgttacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20870 JY8QFUQ01B9I8D productive (see comment) Homsap IGHV3-7*02 F 882 89.86 195/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'CCA' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaAaagggctggagtgggtggccCCAcataaaacccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggcccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaaactc +20871 JY8QFUQ01A1KQO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20872 JY8QFUQ01ABGGA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20873 JY8QFUQ01CRRQI productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +20874 JY8QFUQ01CXT9Y productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20875 JY8QFUQ01AZSTY productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 879 89.09 196/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + ctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20876 JY8QFUQ01B17JU productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARELGGSGTCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); tggatacaccttcaccaggcactatatgcactgggtgcgacaggcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggGggcagagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20877 JY8QFUQ01AKZW4 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 957 94.39 202/214 nt 93.93 201/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD1-26*01 F 1 8 7 18 8.7.18 [1.17.38.11] CARGWAQQAGATFVGWFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctatggtgggtccttcagtggttacacctggaactggatccgccagcCccccagggaaggggctggagtggattggggaaatcaatcatagtggcaggaccaactacaacccgtccctcaagagtcgagtcaccatatcaatagacacgaccaacaaccagttctccctgaagttgacctctgtgaccgccgcggacacggctgtatatttctgtgcgagaggttgggcccaacaagcgggagctacgtttgttggctggttcgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca +20878 JY8QFUQ01CBUHR productive Homsap IGHV4-61*02 F (see comment) 650 77.38 171/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERDRSIGGAAELDSW in-frame + Low V-REGION identity (77,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccaatgtacccatcagtcgtggaggttactactggaattggatccggcaggccgccgggaaggggctggagtggcttggacgtgttgacagtaatggattcgtcaggtacaattcttccctcaaaagtcgcctttctatgtcactagacacgtccaagaatcagatctccctgatattgaggtctgtgatcgccgcagacacggccgtatatttctgtgcgagggagcgtgataggtcgatcggtggagcggcagaacttgactcctggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20879 JY8QFUQ01CD5I4 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaAactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20880 JY8QFUQ01A9KUR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame - tctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20881 JY8QFUQ01AC8AS No results +20882 JY8QFUQ01CN2FS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20883 JY8QFUQ01CHAXX No results +20884 JY8QFUQ01CVW6G No results +20885 JY8QFUQ01A8MS3 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt 94.42 203/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcgatagttactacCtggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20886 JY8QFUQ01AO38F productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 911 90.5 200/221 nt 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagTcccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatcgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20887 JY8QFUQ01BEBPT unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1013 96.33 210/218 nt 95.41 208/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDRVYGGGRA##DHW out-of-frame - stop codons in FR3-IMGT at codon 71 of V-REGION: 'T' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 156 to 156 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtTgaagggccgactcaccatctccagagacaattcCcaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggaggggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20888 JY8QFUQ01C8K0R productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F (see comment) 87 64.58 31/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagacCtccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca +20889 JY8QFUQ01B9VNB productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'CA' (2 nucleotides at position 51 to 52 in the user submitted sequence), (cause frameshift); tctggattcaccttcgggaactatagcatgaactgggtccgccacgctccCAgggaagggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20890 JY8QFUQ01C5D21 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGHSYYVSSGPDY## out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactgggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20891 JY8QFUQ01BH0ZP unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 83 86.36 19/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggattcacgtttagaga +20892 JY8QFUQ01A52XO unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 768 84.58 181/214 nt 83.64 179/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.37.11] CARERGSGPP#GMDVW out-of-frame - Low V-REGION identity (84,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 189 to 189 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 100 of V-REGION: 1 nucleotides (from position 203 in the user submitted sequence), (cause frameshift) gttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagcCcccgaggacacggcgtctactactgtgcgagagaaagaggttcgggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20893 JY8QFUQ01B9XYH No results +20894 JY8QFUQ01CXAGM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame - ttctggattcacttttagcagtcatatgatgagttgggtccgccaggctccagggaagggactggaatgggtctcaagtattcgtgccagtggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgctgtatttgcaaatgtacagcctgagagtcgaggacacggccttatattactgtatgaacgaactcggatattgtagtggtggggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20895 JY8QFUQ01DA39V productive Homsap IGHV4-61*02 F 803 85.07 188/221 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSSSIGGERELDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tgtctggtggccccatcagcagtagtggcttcgcctggacctggatccggcagaccgccgggaagggactggagtggatcggacgtgtttatggtagtgggaataccaattacagtccttccctccagagtcgagtcaccatatcagtagagacgtccaagaatcagttctccctgaggttgacttctgtgaccgccgcagacacgggcctatattactgtgcgagagaacatagtagttcgattggcggagagagagaacttgactcctggggccagggaacccaggtcaccgtctcctcagcatcccctgaccagccccaaggtcttccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +20896 JY8QFUQ01CSEO4 No results +20897 JY8QFUQ01ASUN0 No results +20898 JY8QFUQ01B0AOD No results +20899 JY8QFUQ01A2ZSQ No results +20900 JY8QFUQ01BCUN9 unknown (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt 85.12 183/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 77 of V-REGION: 'T' (1 nucleotides at position 135 to 135 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaggagttattattggagttggatccggcagcCccccaggaaagggactggagtggattggttatattaattatgttgggggAcaccgattacaaCcccctccctcaagagtcgagtcTcccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggtgaccagggttcatcggctnttcccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtccgtggaactcag +20901 JY8QFUQ01B1X31 No results +20902 JY8QFUQ01AZ0N5 productive Homsap IGHV1-3*01 F 966 94.86 203/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARWNNDLDYW in-frame - tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20903 JY8QFUQ01B4F48 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 989 95.81 206/215 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD4-17*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARAEDYGDLTFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctccatcagtacttacttctggagctggatccggcagcccccaggaaagggactggagtggattggctatgtctatcacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagtaatgtgaccgctgcggacacggccgtgtattactgtgcgagagcagaggactacggcgacctcacctttgactcctggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20904 JY8QFUQ01CE6Z9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20905 JY8QFUQ01CB9GB No results +20906 JY8QFUQ01DI39D productive (see comment) Homsap IGHV1-24*01 F 993 96.26 206/214 nt 95.79 205/214 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [0.17.38.11] CAIGAMATW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); cggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaAaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatggggaacgtggtcatcgccctgcctggtccagggcttcttccccccag +20907 JY8QFUQ01A08BN unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggctcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20908 JY8QFUQ01A4KIW productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 806 85.78 187/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +20909 JY8QFUQ01BJG01 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 962 94.42 203/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [0.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons ctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgctagtactacttccatacactatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20910 JY8QFUQ01C1AAH unknown (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F (see comment) 281 65.54 97/148 nt 8 8 X 8.8.X [1.17.14.X] null - No rearrangement found Low V-REGION identity (65,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20911 JY8QFUQ01A6TPF unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD5-24*01 ORF 3 8 7 X 8.7.X [1.17.38.11] CARAPRTATLLD#PG out-of-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgaccccctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20912 JY8QFUQ01CI4AA productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame - ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgactagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20913 JY8QFUQ01B970X No results +20914 JY8QFUQ01DBLR3 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 973 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcCgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20915 JY8QFUQ01B7NSM unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD1-7*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDCDSGECNFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagGggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccgagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20916 JY8QFUQ01CGB1G productive Homsap IGHV3-7*01 F 887 89.91 196/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + cctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20917 JY8QFUQ01A76FU productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 919 91.32 200/219 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [2.17.38.11] CTREVSDALDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcacctttgatgattttggcatgagatgggtccgccaagtcccagggaaggggctacagtgggtctctgggattaattggaatggtgctaaaacaggttatgcagcctctgtgcagggccgattcaccatctccagagacaacgacaacaacgtcctgtatctgcaaatgaacagtttgagacccgaggacacggccttgtatcgctgtacgagagaggtttcggacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20918 JY8QFUQ01B5R5Y unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 739 82.19 180/219 nt 80.82 177/219 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [2.17.38.11] CARGGTDFDY## out-of-frame - Low V-REGION identity (82,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 206 to 206 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'T' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); gcctctggaAtttacatttagtgattataatatgaattgggtccgccgggctccagggaaggggctggaatatgtcgcaaccattacaactgggagtggtcaaatctactacagtgactcagtgaggggccgcttcaccatctctagagacgacgccaagaattcactttatctgcagatgaacaacctgagaggcgaggacacgGgctgtctaTtttttgtgcgagaggggggactgattttgactattgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +20919 JY8QFUQ01B606B productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 15 8.8.15 [1.17.38.11] CVRGGVSGAFRWGFDYW in-frame + ctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctacaaatgaacagtctgagagccgacgacacggctgtttactactgtgtgagagggggagtcagtggggccttcaggtgggggtttgactactggggccagggaaccctggccaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20920 JY8QFUQ01DB6AG productive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 10 7 22 10.7.22 [1.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame - Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20921 JY8QFUQ01B0BK5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20922 JY8QFUQ01BKXRL unproductive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt 97.25 212/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSSPYFYDSNGY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggGggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +20923 JY8QFUQ01ARK7T productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARGGQRTGWYEYW in-frame + cctctggattcacctttagtacctattggatgacttgggtccgccaggctccagggaaggggctggagtgggtggccagcataaaaaatgatggaagtgagaaatcctatgtggactctgtaaagggccgattcaccatctccagagacaacgccgagaactcactgtatttgcaagtgaacaacctgagagccgaggacacggctgtatattactgtgcgagagggggccaaagaactggctggtacgaatattggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +20924 JY8QFUQ01B4T36 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.16.38.11] CVRHVRRFWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) ctctggtgactccatttccagtactagttattactggggctgggtccgccagcccccagggaagggctggagtggattgggggtatctattctagtgggaccacctacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20925 JY8QFUQ01BEWM9 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKYVEGVVIYGGLL##SYAMDVW out-of-frame - ttctggattcgcctttagccgttatgccatgacttgggtccgccagactccagggagggggctggagtgggtctcaggtctcagtggtagtggtgatagcacatactactcaaactccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggagggggtggtcatatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20926 JY8QFUQ01AMSIH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - tctggattcaccttcagtagttatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20927 JY8QFUQ01BF2Q2 unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARVGYGYRGIYFFDY## out-of-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaaccggtgacggtgtcgtggaactca +20928 JY8QFUQ01AUH1C productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt 94.86 203/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaGggggctggtgtgggtctcacgtgttaatggtgatgGggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20929 JY8QFUQ01DAY2V productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 776 83.71 185/221 nt 83.26 184/221 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift); aatgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGgggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20930 JY8QFUQ01DLO83 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1004 95.87 209/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPGGNCLL*WW*#CYDPW out-of-frame + stop codons cctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggaattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +20931 JY8QFUQ01AD0K5 unproductive Homsap IGHV3-11*01 F 862 89.67 191/213 nt 88.73 189/213 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD2-2*01 F 3 8 7 X 8.7.X [1.16.38.11] CARDPYCSSTNCYPY## out-of-frame - in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaagggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactgggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +20932 JY8QFUQ01BA1IP No results +20933 JY8QFUQ01CEBPR productive Homsap IGHV4-34*08 F (see comment) 719 81.86 176/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-14*01 ORF 3 8 7 13 8.7.13 [1.17.38.11] CARGRDYNQNDLGHW in-frame - Low V-REGION identity (81,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagcagctatgccatgagttggatccgccagcccccagggaaggggctagagtgggttggagaagtcaatcatagtggagagccctactacaatccgtccctcaagagtcgagtcagcatctcactagatacatccaagattcatttcaccctaaaactgacttctgtgaccgccgcggacacggctgtgtattactgtgcgagaggccgtgactataaccagaacgaccttggccactggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20934 JY8QFUQ01BSZAM productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 876 90.19 193/214 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20935 JY8QFUQ01C8MN4 productive (see comment) Homsap IGHV2-5*02 F 1102 94.67 231/244 nt 93.85 229/244 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 10 7 14 10.7.14 [9.17.38.11] CAHIRAELSTSCHAFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 183 to 183 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccaggaaAaggctctggagtggcttgcacttgtttattgggatgatgataancgctacagctcatctctgaagagcagactcaccatcaccaaggacacctccAaaaaaccaggtggtccttacaatgactaacatggaccctatggacacagccacatattactgtgcacacattagggcggaacttagtaccagctgccatgccttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +20936 JY8QFUQ01B2NXU unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 620 93.01 133/143 nt 92.31 132/143 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 7 1 X 7.1.X [1.X.38.11] CVSDLAGQKGF## out-of-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01B2NXU ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 38 of V-REGION: 75 nucleotides (from position 27 in the user submitted sequence), (do not cause frameshift) cctcaggattcaccttcagtagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20937 JY8QFUQ01DSG0R No results +20938 JY8QFUQ01CRE1B productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 922 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - tctggagttcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgaganccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20939 JY8QFUQ01A2P3S unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 121 69.81 37/53 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVVWSLWYFDL## out-of-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctgggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20940 JY8QFUQ01C094X productive (see comment) Homsap IGHV3-43*01 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-8*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDRIGSLYYFDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); tcaggattcacatttgGctgaatataccatgcactgggtccgtcaagttccggggaagggtccggagtgggtctctcttattagttgggatggtggcagcacatactatgcagactctgtgaagggccgattcaccatctccagagacaacagcaaggactccctgtatctgcaaatgaacagtctgagaactgaggacaccgccttgtattactgtgcaaaagataggattgggtccttgtactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20941 JY8QFUQ01BC3A6 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 881 90.23 194/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame - tttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20942 JY8QFUQ01CJ3AN unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF## out-of-frame - tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag +20943 JY8QFUQ01C94U1 productive (see comment) Homsap IGHV4-61*02 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 9 7 16 9.7.16 [1.17.38.11] CARERSASIGGAGEIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 37 of V-REGION: 3 nucleotides (from position 30 in the user submitted sequence), (do not cause frameshift) tctctggcggccccatcagtggtggtggttactggagttggatccggcagcccgccgggaagggactggagtggatcggacatatttataatagtgggaacatcaactacagtccctccctcaagagtcgggttttcatgtcagtagacacctctaagaagcagttttccctgaggttgaactctgtgaccgccgcggacacggccgtgtattattgtgcgagagaacgtagtgcttcgattggcggagcgggagagattgactcctggggccagggaatcctggtcaacatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20944 JY8QFUQ01C4MK3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 838 87.21 191/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 8 8 10 8.8.10 [2.17.38.11] CATWIQSHFDYW in-frame + gcctctggattcacatttagtcactataccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagccattaatcaagatgccattaccacacactacccagactccgtgaagggccgcttcaccgtctccagagacaattccaagaacacactctatctgcaaatgagcagcctgagagccgacgacacggccgtatattattgtgcgacgtggatacagtctcactttgactattggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20945 JY8QFUQ01BON0E productive Homsap IGHV3-48*02 F 891 90.32 196/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDHIWAFDFW in-frame + ctctggattcaccttcagtgactatagcatgaactgggtccgccagactccagggaagggggtggagtggatttcatacatcggccgtggtggtgatgggatatactacgcagactctgtgaagggccgaatcaccatctccagagacaatgccaagaactcactttttctgcaaatgaacaccctgagagacgacgacacggctgtgtattactgtgcgagagaccacatttgggcttttgatttctggggccaagggacaaaggttaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20946 JY8QFUQ01CUERK productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 696 80.84 173/214 nt 80.37 172/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggCaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20947 JY8QFUQ01DBT4M unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGS## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggGggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtgggggccagggagccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +20948 JY8QFUQ01B6CKY productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 89.3 192/215 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 2 8 7 17 8.7.17 [1.17.38.11] CAKNLRLGHSYFYNALDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 42 of V-REGION: 'C' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AAGG' (4 nucleotides at position 61 to 64 in the user submitted sequence), (cause frameshift); tctctggtggcctcatcagtaattactattggGacctggatCccggcagccccccaggaaAAGGgcacatggagtggattgggaacatctattacagtgggagcgccacctacaacccctccctcaagagtcgagtcaccatatcaatagactcgtccaagaaccagttctccctgaggctgaccgctgtgaccgctgcggacacggccgtgtattactgtgcgaaaaacttacgattgggtcacagttacttctacaacgctttggacgtatggggccaagggaccacggtcaccgtcgcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +20949 JY8QFUQ01CEXR5 productive Homsap IGHV4-61*02 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20950 JY8QFUQ01DJPEP unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +20951 JY8QFUQ01CLDAG productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtagttactggatgcactgggtccgccaAaactccagGgggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20952 JY8QFUQ01B9SV9 productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20953 JY8QFUQ01AVZIA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKKHYNSGTYLYNFDYW in-frame + ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaaaacattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +20954 JY8QFUQ01AM056 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 8 8 9 8.8.9 [1.17.38.11] CAKEEVPNDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'A' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); tctctggattcaccAtttagcaatgctgccatgacgtgggtccgccaggctccagggaaggggctagagtgggtctcaggtattagtattagtggtgatagaacatattacgcagactccgtgaagggccggttcaccatctctagagacaattccaagaataccgtgtatctgcaaatgaacagcctgagagccgaggacacggccatatattattgtgcgaaagaggaggtcccgaatgattattggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20955 JY8QFUQ01BBZCB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt 86.7 189/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.16.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 33 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) agcctctggattcacctttaccacctccgccaggcctgggtccgccaggttccaggaaggggctggagtgggtctcaactaGttagacctaGgtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20956 JY8QFUQ01BMQPC No results +20957 JY8QFUQ01CDMDY productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 907 90.09 200/222 nt 89.64 199/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggaTttgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20958 JY8QFUQ01AYXDN productive (see comment) Homsap IGHV4-61*02 F 884 89.14 197/221 nt 88.24 195/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 12 10.7.12 [1.17.38.11] C#RDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); in CDR3-IMGT, from codon 105 of V-REGION: 1 nucleotides (from position 222 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccGggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20959 JY8QFUQ01DATD1 productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CATISDYRFEFW in-frame - ctctggattcacctttagtggctattggatgagttgggtccgccaggctccggggaagggtctggagtgggtggccaacatagagaaagatggaagtgacataaagtatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtctctgcaaatgaacagcctgagagccgacgacacggctatttattactgtgcgaccattagtgactaccgatttgaattctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatacctggtccagggcttcttcccccag +20960 JY8QFUQ01B1YMM No results +20961 JY8QFUQ01ABPCL No results +20962 JY8QFUQ01CF74Q unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 792 84.79 184/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20963 JY8QFUQ01CAG3Y productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20964 JY8QFUQ01AK731 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARFGPLTRPDYWG in-frame + cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccaggggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20965 JY8QFUQ01CXN8M productive (see comment) Homsap IGHV1-8*01 F 840 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARVGGTHYHYGVDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 101 of V-REGION: 'C' (1 nucleotides at position 203 to 203 in the user submitted sequence), (cause frameshift); cggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagatctgacgacacggccCgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +20966 JY8QFUQ01DLCGK unproductive Homsap IGHV3-7*01 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CARETLPLGVGG#FDNW out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggGggctggagtgggtggccaacataagccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttggggggtttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20967 JY8QFUQ01C1R0Y No results +20968 JY8QFUQ01CXWFF productive (see comment) Homsap IGHV3-11*01 F 982 94.52 207/219 nt 94.06 206/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); gcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagGggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +20969 JY8QFUQ01B29B8 No results +20970 JY8QFUQ01A5FUX productive (see comment) Homsap IGHV3-30*01 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); cctctggattcacctTtcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20971 JY8QFUQ01AH32A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD2-8*01 F 1 8 8 19 8.8.19 [1.17.38.11] CAKVFQVSGEHHFYYYGMNAW in-frame + cctctggattcatctttagtaattatgccatgagttgggtccgccaggccccagggagggggctggagtgggtctcaactatcagtgccaatggagacaacacatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacagtgtatatgcaaatgaacagcctgaaagccgaggagacggccgtctatcattgtgcgaaagtcttccaggtgtctggcgaacatcacttctactactatggtatgaatgcctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20972 JY8QFUQ01ARP82 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 940 91.11 205/225 nt 89.78 202/225 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [2.17.38.11] CTTAPSETYATEYFAMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 92 of V-REGION: 'A' (1 nucleotides at position 188 to 188 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'AC' (2 nucleotides at position 202 to 203 in the user submitted sequence), (cause frameshift); gcctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaAaaagcacaattgatggtgggacaacatcctacgctgcccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgAaacagcctgaaaaACccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaaggggccccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20973 JY8QFUQ01BEOD5 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 110 68.0 34/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDFW in-frame + stop codons cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggncatggtaatgtctcctagcatcccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +20974 JY8QFUQ01AI044 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 688 91.98 149/162 nt 91.36 148/162 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD3-9*01 F 1 X 7 20 X.7.20 [X.9.38.11] CARHPRPGTFDYLWGGVGSTPG in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); gggaaggggctggagtgccttgggagcatcCttttatagtgggcgcaccaaccaggacccgtccctcaagagtcgagtcaccttatccgttgacacttccaagaaccagttctccctgaagctgagctctgtggccgccgcagacacggctgtgtattactgtgcgagacatccccgcccgggaacttttgactacttatgggggggggttggttcgacccctgggggccagggaattccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag +20975 JY8QFUQ01B0CV7 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 785 84.16 186/221 nt 83.26 184/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFETW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tttccggtagttccatcagtagcagtgattactactgGgggctgggtccgccagTcccccagggaagggtctggagtggattggaagtgtctattacagggggacgcagtacctcaacccgtccctccagagtcgagtttccatttccattggcacgtccaagacgcaattctccctgagactgaggtctgtgaccgccgcagacacggctatgtattactgtgcgagacatcggtcttttggagtgataattgtgaattactttgagacctggggacagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20976 JY8QFUQ01BSPOJ unproductive (see comment) Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [1.17.38.11] CARPAGAG*PFFA#YYSGLDVW out-of-frame + stop codons ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggcagggtgacccttttttgccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20977 JY8QFUQ01CZEEB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F (see comment) 381 76.69 102/133 nt 75.19 100/133 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 X 6 16 X.6.16 [X.X.38.11] CVRYDYSRLHRSNYFGPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (76,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 76 of V-REGION: 'T' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 82 of V-REGION: 'A' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); gtctctggattcaccttcatcagttatgactcccgtgaagggccggttTcaccatctccagagacaAattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20978 JY8QFUQ01BVL5V unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CAREKGSGPP#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20979 JY8QFUQ01CQ9Q9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame - cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +20980 JY8QFUQ01BHX3H productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt 90.32 196/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-8*02 F 2 8 8 20 8.8.20 [1.16.38.11] CARDLWLCSGGECYHRGGFENW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 44 in the user submitted sequence), (cause frameshift) cctctgggttcaccttcagtGaactcctggatgcGactgggtccgcaaactccagggaagggggccgagtgggtctcacgtattaatagtgatgggagtaatacaatctacgAcggactccgtgaagggccgactcaccatctccagagacaacgccaaAaaacacggtgtatctgcaattgaacagtctgagagccgaggacacggctgtgtactactgtgcaagagatctgtggctttgtagtggtggtgaatgctatcatcggggtggttttgagaactggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +20981 JY8QFUQ01CCX4A unknown (see comment) Homsap IGHV3-30-2*01 P, or Homsap IGHV3-30-33*01 P or Homsap IGHV3-30-52*01 P or Homsap IGHV3-33-2*01 P or Homsap IGHV3-54*01 P or Homsap IGHV3-54*02 P or Homsap IGHV3-54*04 P 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found actctggatt +20982 JY8QFUQ01CNTN4 productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctgcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcaggc +20983 JY8QFUQ01BSBCH unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ6*01 F (see comment) 144 69.84 44/63 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFGRT# out-of-frame + Other possibilities: Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttggacgtactggggccagggaacctggtcaccgtctcctcagcctccagccaaggccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtg +20984 JY8QFUQ01AWSWI productive (see comment) Homsap IGHV3-30*01 F 859 88.89 192/216 nt 87.04 188/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.37.11] CARDSVPRASEAAYHFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 94 of V-REGION: 'T' (1 nucleotides at position 186 to 186 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 212 to 212 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 82 of V-REGION: 1 nucleotides (from position 149 in the user submitted sequence), (cause frameshift) ctctggattcGtccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacattccaagaacacgctgtttctgcacatgaacagccTtgagagttgaggacacggctgtttaCtttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +20985 JY8QFUQ01BW66J No results +20986 JY8QFUQ01AK5T8 productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt 89.59 198/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AT' (2 nucleotides at position 98 to 99 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'AC' (2 nucleotides at position 124 to 125 in the user submitted sequence), (cause frameshift); tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcaGgcccccagggaagggactggagtggattggtcatttctatcacaATttgggggcactaagtacaacccctACccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20987 JY8QFUQ01B2XYK productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARRGSYGSGSYYPW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcagacacggctgtgtatcactgtgcgagacgtggttcctatggttcggggagttattatccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20988 JY8QFUQ01A7H6S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaagactacttccccgaaccggtgacggtgtcgtggaactcag +20989 JY8QFUQ01B65DZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 868 89.35 193/216 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CANEVGYCSGGG in-frame - tctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggagctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtggggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20990 JY8QFUQ01DWTOU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +20991 JY8QFUQ01A0207 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +20992 JY8QFUQ01C0T0E productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.74 200/218 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CGKPIVGATGREMPVSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagcaactatgccatgaactgggtccgccaggttccaggggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20993 JY8QFUQ01DBMCS unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 980 93.3 209/224 nt 92.86 208/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 X 8.7.X [4.17.38.11] CARGGPHFMI (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); cctctgcagcctctgggAttcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggcccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +20994 JY8QFUQ01B7NNR No results +20995 JY8QFUQ01B2GU8 productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 91.63 197/215 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 92 to 97 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagtttctGactggagttggatgaggcagcCccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +20996 JY8QFUQ01B1UMW productive (see comment) Homsap IGHV3-11*01 F 982 94.52 207/219 nt 94.06 206/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift); gcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactcCtgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +20997 JY8QFUQ01C0LCZ unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt 98.62 214/217 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGHCISTSCYWEIHYYYGMDV## out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctatagcatgaactgggtccgccaggctccagggaaGggggctggagtgggtctcatccaAttagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20998 JY8QFUQ01CCD9I productive Homsap IGHV3-7*01 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [0.17.38.11] CARGSYWHYDTFGDYW in-frame - tggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +20999 JY8QFUQ01BLO0V unproductive (see comment) Homsap IGHV3-7*01 F 969 93.64 206/220 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD5-18*01 F 3 8 8 16 8.8.16 [2.17.38.11] CARVGYGYRGIYFF*LLG in-frame + stop codons agcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttcttttgactactgggggccagggaacccctggtcaccgtctcctcagctccaccaagggcccatcggtcttccccctggcgccctgctccagagcacctccgagagcacagcgccctgggctgctggtnaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21000 JY8QFUQ01BTHIY No results +21001 JY8QFUQ01B4FME productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRDRFYDSSGYEFGELGDYSDHW in-frame + cctctggattcacatttagtaactactggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctgtgtgagagatcgattttatgatagtagtggttatgagtttggggaattgggggactactctgaccactggggccagggaacccaggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcaccctccgagagcacagccgccctgggctgcctggtcaaggactaccttccccggaaccggtgacggtgtcgtggaactcca +21002 JY8QFUQ01AQCY5 No results +21003 JY8QFUQ01BNK8R productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 799 86.38 184/213 nt 84.51 180/213 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 7 9 8.7.9 [1.16.37.11] CTGLTYPDDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 81 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 120 in the user submitted sequence), (cause frameshift) gtctggatttaccttcagtaagttctggatgcattggtccgccaagctccagggaagggctgacttgggtctcacgtataatcctgatgggactatcacgaactacacggactccgtgagggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21004 JY8QFUQ01CH7L4 unproductive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1049 96.04 218/227 nt 95.15 216/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 X 10.9.X [1.17.38.11] CTRGSSRGG*I**ELL*A#DFW out-of-frame + stop codons in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'AT' (2 nucleotides at position 137 to 138 in the user submitted sequence), (cause frameshift); ctccgggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccCccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaaATgtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggtagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggcttcttcccccg +21005 JY8QFUQ01DJ07A No results +21006 JY8QFUQ01BP78X No results +21007 JY8QFUQ01CY4KM unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ2*01 F (see comment) 94 64.15 34/53 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKNRGVGDG*LVLRFL# out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'ATG' (3 nucleotides at position 87 to 89 in the user submitted sequence), (do not cause frameshift); ctctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattactaATGgtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttatttctgtgcgaaaaataggggggtcggcgatggctgactggtacttcgatttctgggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21008 JY8QFUQ01DLQMH productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 901 90.41 198/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDLYGADDLW in-frame - acctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21009 JY8QFUQ01DCK0R productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame - ctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21010 JY8QFUQ01B7Z25 productive (see comment) Homsap IGHV3-9*01 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [2.17.38.11] CVKNNGYFYDVAGYFDDW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 169 to 169 in the user submitted sequence), (cause frameshift); gcctctggattcacctttgacaattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtcgcaagtattagttggaatagtggaagcgcagactatgcggactctgtgcggggccgattcaccatctccagggacaacgccaagaactcccttTtttctgcagatgaacgatctgagacatgaggacacggccgtctatttctgtgtaaaaaataacggatatttctatgatgttgctggctactttgacgactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +21011 JY8QFUQ01AAQDQ No results +21012 JY8QFUQ01B664T productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactc +21013 JY8QFUQ01DL1HS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21014 JY8QFUQ01CB8LO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 3 8 8 14 8.8.14 [1.17.38.11] CAKVGVMSARDRIDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); cctctggattcaccGtttagcaactatgccatgagttgggtccgccaggctcaagggaaggggctggactgggtctcagatattagtaatagtggtggtgacacattctacgcaggctccgtgaagggccgcttcaccatctccagagacaattccaggaacactctatatctgcaaatggacagcctgagagccgaggacacggccgtgtattactgtgcgaaagtgggggtgatgtccgctcgagaccgcattgactactggggccggggaaccctggtctccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21015 JY8QFUQ01CPPNL unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD3-16*01 F 1 8 7 X 8.7.X [1.17.38.11] CASANYDYVWGELSL*LL# out-of-frame - stop codons ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggggagttatcgttatgactactgggggccagggaaccctggtcaccgtctccctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21016 JY8QFUQ01BAK8M unproductive Homsap IGHV4-59*03 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD2-21*02 F 2 8 7 X 8.7.X [1.17.38.11] CARGRTVVTVIDYMDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'AA' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift); tctctggtgactccattagcggttactattggacctggatccggcaaacccccaggaaAAgggactggagtggattggaaatatccactacagtgggagcaccaagtacagtccctccctcaagagtcgagtcaccatatcactcgccacgtccaagaatcaattcgccctgaagttgacctctgtgaccgctgcggacacggccgtctattattgtgcgagaggacgaacggtggtgactgttattgactacatggactactgggggtcagggaacccctggtcaccgtctcctcagatccccgaccagccccaaaggtcttcccgctgagcctcctgcagacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21017 JY8QFUQ01B7RQH productive Homsap IGHV3-21*04 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21018 JY8QFUQ01DLJRJ productive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARCPNYNIGTRGFDYW in-frame - tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +21019 JY8QFUQ01A3LQU productive (see comment) Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt 81.11 176/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattccCccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21020 JY8QFUQ01DOV6Q No results +21021 JY8QFUQ01CN6IE productive (see comment) Homsap IGHV3-66*02 F 903 91.59 196/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.16.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'C' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) cctctggattcaccgtcagtagcagcttcatgaCtttgggtccgccaggctccaggaaaggactggagtgggtctcagtGcttttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21022 JY8QFUQ01CYHKC No results +21023 JY8QFUQ01BILLB productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1051 97.3 216/222 nt 96.4 214/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [2.17.38.11] CARLDYTRYFDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagcagtagtagTttactactGggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccaag +21024 JY8QFUQ01B88T2 No results +21025 JY8QFUQ01BAL7P productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1085 100.0 218/218 nt 99.08 216/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-2*01 F 2 8 8 17 8.8.17 [2.17.37.11] CAKPSSTSSRARTSHFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 178 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaatAaaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgaagcctagtagtaccagctcccgcgctcgcacctctcactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21026 JY8QFUQ01BOFYV unproductive Homsap IGHV3-11*01 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKGETVVTPGDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaTggggctggagtgggtttcatacattagtaatggtggtagtctcgtattctacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatttacaaatgaatagtctgagacctgaggacacggccttatattactgtgcaaaaggagagacagtggtaactccaggagactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21027 JY8QFUQ01BUZGQ productive Homsap IGHV3-11*01 F 855 88.48 192/217 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD1-1*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGTTASW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctttggattcaccttcaaggactactacatgagttggatccgtcaggctccagggaaggggctggagtgggtctcatacatatctcatgatggtgcgaccaaatactacgcagactctgtgcagggccgattcaccgtctccagggacaacgccaagaactcactgtatctgcaaatgaacaacgtgagagccgacgacacggccttctattattgtgcgagagacctcgtgggcacaactgcatcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21028 JY8QFUQ01CIJGA unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 841 87.96 190/216 nt 87.04 188/216 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [2.17.37.11] CAKNNNDFGDYDWF#PW out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'T' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) gtctctgggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattacTactgggggcaccgactccaacccctccctcaagagtcgtgtcaccctgtcaatggacacgtccagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgaccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21029 JY8QFUQ01CJ620 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 835 88.26 188/213 nt 87.79 187/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.37.11] CARKGLVPSMFFFDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 192 in the user submitted sequence), (cause frameshift) ctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccgggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21030 JY8QFUQ01DKPE3 No results +21031 JY8QFUQ01CF24Z unproductive (see comment) Homsap IGHV1-18*01 F 894 91.12 195/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [0.17.38.11] CARSHGGTAAGR#FDFW out-of-frame - stop codons Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) tggttacgcctttaagaactatggtatcaactgggtgcgacaggcccctggacaagggcttgagtggatggcatggatcagcgtatacaatggaaacacaaagtttgcaccgaggttccaggccagagtcaccatgactacagacacttccacgagcacagcctacatggaactgaggagcctgagatctgacgacacggccatgtattactgtgcgagatctcacgggggaacagcagctggacgaatttgacttctggggccaggggaccgtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21032 JY8QFUQ01A4RRU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKASPKWEFLRTTFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGcctttcgcagctatgccatgacctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtgctggtagcacattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgacgacacggccatctacttctgtgcgaaggcgtcgccgaagtgggagtttctacgaaccacctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21033 JY8QFUQ01AE0GU No results +21034 JY8QFUQ01A0IZI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 938 91.4 202/221 nt 90.5 200/221 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 82 to 84 in the user submitted sequence), (do not cause frameshift); cagcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaAaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21035 JY8QFUQ01AZY50 productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + ctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgctctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21036 JY8QFUQ01CJGR0 No results +21037 JY8QFUQ01AL56R productive (see comment) Homsap IGHV1-2*02 F 867 89.72 192/214 nt 88.79 190/214 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [0.17.38.11] CARDPGDPRSYWYFDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); tggatacaccttcaccgactactatatacactgGggtgcgacaggcccctgggcaagggcttgaatggatgggatggaCccaaccctaagagaggtgactcgaggtatgcacagaagtttctgggaagggtcaccatgaccagggacacgtccctcactacaacttacatggaactgagcagcctcagatctgacgacacggccgtgtattactgtgcgagagatcccggagacccccgaagctactggtacttcgatgtctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21038 JY8QFUQ01DLUXO No results +21039 JY8QFUQ01B0AIT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFGRT (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION cctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttggacgtactggggccaggaacctggtcaccgtctcctcagctccagccaaggccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21040 JY8QFUQ01CEXGP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 838 87.21 191/219 nt 86.76 190/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 1 8 8 11 8.8.11 [2.17.38.11] CARDGEWEMLDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggGggctggagtgggtctcacgcattaaaagtgatgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacatatttttgtgcaagagacggggagtgggagatgcttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcccctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21041 JY8QFUQ01AS325 productive (see comment) Homsap IGHV3-48*01 F 1076 99.54 217/218 nt 99.08 216/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggGAagggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21042 JY8QFUQ01C88ZB unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 982 94.52 207/219 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CAGHLLGDPFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ggttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggcccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21043 JY8QFUQ01AORAJ productive Homsap IGHV1-8*01 F 817 87.32 186/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 12 8.8.12 [X.17.38.11] CARGRGYGSYADHW in-frame - ggatacagcttcagcaattatgatatcaactgggtgcggcaggccactggacaagggcttcagtggatggggtggatgaacccccacagtgccaatatcgtctacgcgcagaaatttcagggcagagtcaccatgaccagtgacgcctccataaccacagcctacatggaactgagcaacctgaaatctgacgacacggccgtgtattattgtgcgaggggccgagggtacggaagttacgctgaccactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21044 JY8QFUQ01DLT55 productive (see comment) Homsap IGHV3-23*05 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctcgacagcacccccccgaagatgggaaaccgtggtcgtcgcatgcctggtccagggcttcttcccccaa +21045 JY8QFUQ01CM4YG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 1 8 8 18 8.8.18 [1.17.38.11] CAKVLAGATRDAYHYGMDVW in-frame + cctctggatttactttcagtaggtctgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggcattagtggtggtggtcttagcacatactacacagactccgtgaagggccggttcaccatctccagagacatttccaagaacacgctgtttctgcaaatgaacagcctgagagccgaggacacggccacatattactgtgcgaaagtcctggcgggagctacgagggacgcctaccactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21046 JY8QFUQ01CNZ0T unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CARGHSYYVSSGPDY## out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactgggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21047 JY8QFUQ01DNKTR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 853 89.2 190/213 nt 86.38 184/213 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 3 7 8 21 7.8.21 [2.15.37.11] CAKYVEGWSYTGGYYNSYAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 2 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 55 of V-REGION: 2 nucleotides (from position 77 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 67 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) aacttctggattcgcctttagccgtatgccatgacttggtccgccagactccagggaggggctgagtgggtctcagtCtcagtggtagtggtgatagcacatacactcaaactccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggaggggtggtcatatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21048 JY8QFUQ01C1HAH productive Homsap IGHV3-21*04 F (see comment) 658 78.08 171/219 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.17.38.11] CVRLFTSDGVRGDYW in-frame + Low V-REGION identity (78,08% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctccggtttcatcttcagtcacttcagcatgaactgggtccgccagactccaggaaagggcctggagtggatcgccgacatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcgacgatacggccacctattattgtgtgaggctcttcaccagcgatggagtgagaggcgactactggggccagggcgcccgggttctcgtctccgcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21049 JY8QFUQ01B0QWC productive Homsap IGHV3-48*02 F 986 94.95 207/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARPAGEGDPFFHYYSGLDVW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21050 JY8QFUQ01DQMT6 No results +21051 JY8QFUQ01CZEY6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDGVRGVGAYYIYYF#DLW out-of-frame + cctctggattcacctttggcctctatgccatgaactgggtccgccagactccagggaaggggctggagtggctcgcaactattagtggtagtggaagtagatcattttacgcagactccctgaagggccggttcaccatctccagagacaattccaagggcacggtatacctggaaatgaccaccctgagagccgaggacacggccgtatattactgtgcgagagatggggtccgtggcgttggtgcttactacatctactatttttcgacttatggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21052 JY8QFUQ01DT4J9 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.48 192/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 213 to 213 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccaactGacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatTttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21053 JY8QFUQ01AT5B3 No results +21054 JY8QFUQ01C8610 No results +21055 JY8QFUQ01CTQAV unknown (see comment) Homsap IGHV2-5*03 F (see comment) 258 59.38 114/192 nt 10 7 X 10.7.X [9.17.27.X] null + No rearrangement found Low V-REGION identity (59,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagccccccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccta +21056 JY8QFUQ01CLVFK unproductive Homsap IGHV3-48*03 F, or Homsap IGHV3-48*04 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKDGSAIPVTGTYFEY## out-of-frame + gcctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccaagggagccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21057 JY8QFUQ01DTBKZ unproductive Homsap IGHV3-30*01 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD3-3*01 F 1 8 8 X 8.8.X [1.17.38.11] CACGHMRDGYDVW# out-of-frame + in FR3-IMGT at codon 66 of V-REGION: 'G' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaaGtactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctgggggcccaagggacaaaggtcaccgtctcttcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctcggtccagggcttcttcccccgagg +21058 JY8QFUQ01AVNX2 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame - ctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21059 JY8QFUQ01BQSNT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CIMDLVGRADYW in-frame - cctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21060 JY8QFUQ01C8YUV No results +21061 JY8QFUQ01DOEOY unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [1.17.38.11] CTREVGSYRLL## out-of-frame - cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtggggagctaccgactactgggggccaggggaacccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag +21062 JY8QFUQ01BMF7P productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame - ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21063 JY8QFUQ01BZ1OJ productive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 10 7 22 10.7.22 [1.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21064 JY8QFUQ01CEQO2 unproductive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt 95.85 208/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSGYYSTGY## out-of-frame - in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +21065 JY8QFUQ01CWKZQ No results +21066 JY8QFUQ01BG0IA unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 165 75.0 45/60 nt 8 X X 8.X.X [1.10.X.X] null - No rearrangement found gctctggattcaacttcagaacctattggatgggctgggtccgccaggcttcttccccca +21067 JY8QFUQ01CR4HU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21068 JY8QFUQ01CPCWU unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtc +21069 JY8QFUQ01BZEC4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt 86.11 186/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.37.11] CARDDGGHMTLDV# out-of-frame + in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctgggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtgcgtggaactca +21070 JY8QFUQ01CDREL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 7 12 8.7.12 [1.17.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +21071 JY8QFUQ01AVF6B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21072 JY8QFUQ01BFXCP unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 815 86.24 188/218 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKVGNLYFFEY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccgggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +21073 JY8QFUQ01AM5NG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21074 JY8QFUQ01DRIRL productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 974 93.67 207/221 nt 93.21 206/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 2 10 7 12 10.7.12 [1.17.38.11] CVRHRRLELLPDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 174 to 174 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggaatatctattatagtgggagcacctactacaacccgtccctcgagagccgagtcaccatatccgtagatacatccaggaaccagttctccCctgaagctgaggtttgtgaccgccgcagacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccancccctcaaggtcttcccgctgagcctctgccagcacccagccagtgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +21075 JY8QFUQ01A019O productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaCccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21076 JY8QFUQ01BMY2A productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 937 92.24 202/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [2.17.38.11] CARLPNTIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'CG' (2 nucleotides at position 76 to 77 in the user submitted sequence), (cause frameshift); gcttctggatatagtTtttggccaccactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatCGgggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatttcagccgacaagtccctcagtatcgcctacctgcagtggagcagcctgcaggcctcggacaccgccatatattactgtgcgagactgcctaacactattgactcctggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +21077 JY8QFUQ01BYX2O unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [0.17.38.11] CAARI**WSLL##AFDIW out-of-frame + stop codons tggatacagtttcaccaactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctggtgactctgatacccggtacaacccgtccttccaaggccaggtcaccttctccgtcgacaagtccatcaacaccgcctacttgcagtgggacagcctgaagacctcggacaccgccaagtattactgtgcggcgagaatttgatagtggtcattactggaatgctttcgatatatggggccaagggacgatggtcaccgtcgcttcagcatccccgaccagccccaaaggttcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +21078 JY8QFUQ01BBBC7 unproductive Homsap IGHV4-39*02 F 938 91.86 203/221 nt 90.5 200/221 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-9*01 F 2 10 7 X 10.7.X [1.17.38.11] CARLLRVYDWYSQRGLL#DTW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 209 to 209 in the user submitted sequence), (cause frameshift); tctccgatggctccatcagcactagtaattactactgGgggctgggtccgccagcccccagGggaaggggctggagtggattggaagtatatattatagtgggagcaccgactacagctcgtccctcaggagtcgcgtcaccatatccagagacacgtccaagaaccacttctccctgaaggtgacctctgtgaccgccgcagacacgGgctatatattactgtgcgagactcttacgggtttatgactggtacagtcaaagggggttacttcgacacctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctcccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +21079 JY8QFUQ01A83DU No results +21080 JY8QFUQ01AV41Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21081 JY8QFUQ01BEU3B No results +21082 JY8QFUQ01CR8CN productive Homsap IGHV3-30*19 F (see comment) 675 80.77 168/208 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-11*01 ORF 2 6 8 23 6.8.23 [X.17.38.11] CAKSEVVAVNEGLTLHYSYYRLDTW in-frame + Low V-REGION identity (80,77% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgccggggattctgtcattcactgggtccgccaggctccaggcaggggactggaatggctggcagttatatcacaggatgcatattacacacattacacagacgctgtgaagggccgattcaccatctccagagacaactccaagaatatgctgtttctgcaaatgaacagtctgaggcttgaagacacggccgtctattactgtgcgaaatccgaggtcgtggctgtaaacgagggcctcaccctccactactcctactaccgtctggacacctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctgtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +21083 JY8QFUQ01CW7W3 unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 91 79.31 23/29 nt 7 X X 7.X.X [2.X.X.X] null + No rearrangement found tctccgggggacagtgtctctaccaacag +21084 JY8QFUQ01BZ9NZ productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +21085 JY8QFUQ01CXV9K productive Homsap IGHV3-9*01 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame - ctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +21086 JY8QFUQ01CV8MT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 766 83.56 183/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [2.17.38.11] CTGLTYPDDYW in-frame - Low V-REGION identity (83,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgtctggattttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21087 JY8QFUQ01DNAOD No results +21088 JY8QFUQ01BRSI9 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 911 90.5 200/221 nt 89.59 198/221 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); aggcctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatacCtggtggtacaacagagtacgccgactccgtgaaGggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21089 JY8QFUQ01BOHMH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 956 92.76 205/221 nt 91.4 202/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [2.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); cagcctctggattcatcttcagtagctactggatgcactgggtccgccaagctccaGgggaaggggctggtgtgGggtctcacgtactaataCcgggggggactagcacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +21090 JY8QFUQ01CL2GL productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 956 92.76 205/221 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [2.17.38.11] CAREVSDALDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ttgcctctggattcatctttgatgattttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +21091 JY8QFUQ01DBTOV unproductive Homsap IGHV1-2*02 F 921 92.52 198/214 nt Homsap IGHJ4*02 F (see comment) 114 70.83 34/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [0.17.38.11] CARGGRRGNYYWGI#DSW out-of-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggatacacgttcaccgactactatgtccactgggtgcgacaggcccctggacaagggcttgagtggatggcgtggatcaaccctaacattggtgtcaccaagtctgcacaaaaatttcagggcagggtcaccatgaccagggacacgtccatcagcacagccttcatggagctgagcagcctgagatctgacgacacggccgtttattactgtgcgagaggggggcgacgtgggaactattattggggaatcttgactcctggggccagggaaccctggtcaccggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21092 JY8QFUQ01BNKGX productive (see comment) Homsap IGHV3-7*01 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYYYYDTNGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggatttacctttacaaattattggatgagctgggtccgccaggctccagggaGgggggctggagtgggtggccagcgtaaaacaagatggaggtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggtcctactattattatgatactaatggcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21093 JY8QFUQ01DFN8I No results +21094 JY8QFUQ01CZE4H productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcaaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21095 JY8QFUQ01B6YPA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 693 80.18 174/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGLGLNAVYAFDVW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcgcttttggagattatgccatgaactgggtccgccaggccccagggaagggactggagtgggtctcaggtttgagcggtagaggcgtcagcaaatattatgcagactccgtgaggggccggttctccatttccagagacaactccgggagcgaggcagtccttcaaatgagcagcctgagagtcgaggacacggccacttactactgtgcgaggggcctagggcttaatgctgtctacgcatttgacgtctggggacaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21096 JY8QFUQ01CUQL5 productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 203 to 203 in the user submitted sequence), (cause frameshift); ctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgGggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21097 JY8QFUQ01CU5CB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 905 90.83 198/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'T' (1 nucleotides at position 172 to 172 in the user submitted sequence), (cause frameshift); cctctggattcacctTttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatTctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgncagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +21098 JY8QFUQ01AZ407 unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F 340 88.51 77/87 nt X X X X.X.X [X.X.29.X] null - No rearrangement found gtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactcgggggcgagggaaccctgagtttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21099 JY8QFUQ01CPNTD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + cctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +21100 JY8QFUQ01AA512 productive (see comment) Homsap IGHV3-66*02 F (see comment) 706 81.02 175/216 nt 80.56 174/216 nt Homsap IGHJ6*02 F (see comment) 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 7 21 8.7.21 [2.16.38.11] CSSAAGLDCSGYSCYYFYHMDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) gcctctgggattgaacgtcagtgcgaagttcatgagttgggtccgccaggctccagggaagggctggaatgggtctccactgtctctaacggtggtagtatatattatgcggactccgtgaagggccgatttagcgtctccagagacagctccaagaacacactgtttcttcaaatgaacggcctgagcggtggtgacacggctgtgtacttctgttcgagcgccgctggacttgattgttctggttacagctgttattacttctaccatatggacgtctggggccgagggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc +21101 JY8QFUQ01C91JV No results +21102 JY8QFUQ01CEVCS unknown (see comment) Homsap IGHV3-7*02 F 123 60.71 51/84 nt 8 1 X 8.1.X [2.17.X.X] null + No rearrangement found gcctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +21103 JY8QFUQ01BPSNH unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFGGGSYYLELL*LL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaatttgggggtggcagctactacttggaacttctttgactactggggcccagggaaccctggtcaccgtctcctcagcctccacaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagaactacttccccgaaccggtgacggtgtcgtggaact +21104 JY8QFUQ01BWBPY productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 144 to 144 in the user submitted sequence), (cause frameshift); ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgtggactccgtgaagggccgattcaccatctccCagagacaattccaagaacacggtgtatttgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21105 JY8QFUQ01ABKDV productive Homsap IGHV4-61*02 F (see comment) 614 75.57 167/221 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARERTNSIGGPRHLDPW in-frame + Low V-REGION identity (75,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtgctccgatcaacaatagtgattgctcttggacgtggatccggcagtccgccgggaggggactggagtggattggacgtgtccgtgtgaatggccagagcgactacaatccgtccttcggcagtcgtctcaccatgtccattgacacgtccaggaatcgattttccctgcaattgatctctgtgaccgccgcagacacggccctatattattgtgcgagggaacgtactaattccattggcggaccaagacaccttgacccctggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +21106 JY8QFUQ01AU136 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.37.11] CAKDGARGGGSCFNSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 206 in the user submitted sequence), (cause frameshift) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggcctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21107 JY8QFUQ01BXCKZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 849 88.79 190/214 nt 87.85 188/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 7 8 15 7.8.15 [2.16.38.11] CAKSVSSGWPIDEIDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 37 of V-REGION: 2 nucleotides (from position 26 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 48 in the user submitted sequence), (do not cause frameshift) ggctctggattcacctttaatagcttgcatgagttgggtccgccagtcagggagggggctggagtgggtctcagccattagtggcagtggtagtcggacatattacgcagactccgtgaagggccggttcaccatctccagagacaagtccaagaaaacgttgtatctacaaatgaacagcctgagagccgaggacacggccactttctattgtgcgaagagtgtgagtagtggctggccgatcgacgaaattgactactggggccaggggacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21108 JY8QFUQ01A3JL4 productive Homsap IGHV3-7*03 F 847 87.67 192/219 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [2.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) gcctccggattcatttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaataaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21109 JY8QFUQ01DOYXH unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 679 94.08 143/152 nt 8 8 X 8.8.X [1.17.16.X] null + No rearrangement found cctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaat +21110 JY8QFUQ01AWOO7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 3 8 8 10 8.8.10 [1.17.38.11] CASFRVLESGYW in-frame + tctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21111 JY8QFUQ01BX3V8 No results +21112 JY8QFUQ01CAZTK productive (see comment) Homsap IGHV4-59*03 F 899 91.16 196/215 nt 90.7 195/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-23*01 ORF 3 8 7 9 8.7.9 [1.17.38.11] CARGVTPEGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgggtgactccatcactcctaactcctggagctggatccggcagcCccccagggaagggactggagtggattggttatatctattacagtggaatcaccaagcacaacccctccctcaagagtcgagtcgccatttcagtagacacgtccaagaaccaattttccctgaggctgagttctgtgaccgctgcggacacggccgtttatttctgtgcgaggggggtcactccggagggctactggggccagggaatcttagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21113 JY8QFUQ01CBOD2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 425 80.92 106/131 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 X 5 16 X.5.16 [X.X.38.11] CVRYDYSRLHRSNYFGPW in-frame - Low V-REGION identity (80,92% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcatcagcttatgactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21114 JY8QFUQ01B6UYE productive Homsap IGHV3-7*01 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + gctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21115 JY8QFUQ01COFJ4 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 926 90.62 203/224 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD3-22*01 F 3 8 10 24 8.10.24 [1.17.38.11] CATDRPYYKKSLLADSGITTVWTFWG in-frame + tctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaaatcgctgctggccgactctggtattactacggtatggacgttttgggggcccaaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21116 JY8QFUQ01CER0W No results +21117 JY8QFUQ01BBQCT No results +21118 JY8QFUQ01AT1UN unproductive Homsap IGHV3-48*01 F (see comment) 734 83.73 175/209 nt 83.25 174/209 nt Homsap IGHJ1*01 F 125 71.15 37/52 nt Homsap IGHD5-12*01 F 1 7 7 X 7.7.X [X.17.38.11] CSRDGRRGYDLDS## out-of-frame - Low V-REGION identity (83,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 78 in the user submitted sequence), (do not cause frameshift) gattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctgggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21119 JY8QFUQ01B0HK9 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + stop codons in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaGggggctggagtgggtgtcagatattagtgGggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgtaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21120 JY8QFUQ01CLL7S unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 842 87.61 191/218 nt 87.16 190/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKQKT*LW#YYFDQW out-of-frame + stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacgtttaaaacacatgccatgagctgggtccgccaggctccaggaaaggGggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaaaacatagttatggatactactttgaccagtggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +21121 JY8QFUQ01AMAL4 productive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARCPNYNIGTRGFDYW in-frame + tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21122 JY8QFUQ01BWXXW productive Homsap IGHV3-48*02 F 896 90.37 197/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [1.17.38.11] CARGQKWLQVLRWFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21123 JY8QFUQ01CNRMU No results +21124 JY8QFUQ01CJ6HN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21125 JY8QFUQ01DC0EC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +21126 JY8QFUQ01CNYJJ No results +21127 JY8QFUQ01C1T8I No results +21128 JY8QFUQ01B84MI No results +21129 JY8QFUQ01B43QQ productive (see comment) Homsap IGHV3-72*01 F 880 88.74 197/222 nt 87.39 194/222 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 7 10 11 7.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) ctctggattcatttttagcaatatgccatgaactgggtccgccaggctccaggGgaaggggccggagtgggttggccgtactaaaaacaAaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21130 JY8QFUQ01CRAJJ unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 135 55.56 75/135 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21131 JY8QFUQ01BFS7D productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcgggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21132 JY8QFUQ01AO7UV unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt 92.41 207/224 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); cctctgcagcctctggattcattgtcaatagcaactacatgagttgGggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcCccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagancacagcggcccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21133 JY8QFUQ01A6H7V productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame + gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21134 JY8QFUQ01A93RR productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21135 JY8QFUQ01AW74Z unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 955 93.15 204/219 nt 92.24 202/219 nt Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [2.17.38.11] CARPFSGRWCFDL## out-of-frame + Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 56 of V-REGION: 'AT' (2 nucleotides at position 83 to 84 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaaATtaaaaagtgatgggagtaCccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctgggggccgtggcaccctggtcactgtctcctcagcatccccgactagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21136 JY8QFUQ01APNW6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21137 JY8QFUQ01BAD2S unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1086 99.55 219/220 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD2-2*01 F 3 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctaagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21138 JY8QFUQ01BBX3M unproductive Homsap IGHV3-30*01 F 914 91.28 199/218 nt Homsap IGHJ2*01 F (see comment) 94 64.15 34/53 nt Homsap IGHD6-6*01 F 1 8 8 X 8.8.X [1.17.38.11] CAREWAASHFDHW# out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ccgctggattcaccttcagtggctttgctttgcactggctccgccaggctccagacaaggggctagagtgggtgggatttacatcatttgatgggagtaacagagactacgcagactccgtgaagggccgattcacgatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagacctgacgacacggctgtatattactgtgcgagagagtgggcagccagtcactttgaccactgggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21139 JY8QFUQ01AHPQS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcaaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21140 JY8QFUQ01CDO45 No results +21141 JY8QFUQ01B8W70 productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +21142 JY8QFUQ01A9N5Z No results +21143 JY8QFUQ01C98E1 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 157 72.58 45/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CAREKWFGPPR#GMDVW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaatggttcgggcccccccgacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggccaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21144 JY8QFUQ01C4RLG No results +21145 JY8QFUQ01C597W No results +21146 JY8QFUQ01ANM82 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - tctggattcaccttcagtagctatggcatgcattgggtccgccaggctccaggcaaggggctggagtgggtggcagttatttggtatgatggaagtaataaattctattcagactccgtgaagggccgattcaccatctccagagacaattctgagaacacgctgaatctgcaaatgaacactctgagaagcgaggacacggctgtgtattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21147 JY8QFUQ01AJJLV No results +21148 JY8QFUQ01B8BYJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21149 JY8QFUQ01B2RPD No results +21150 JY8QFUQ01CVR9F productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 923 91.74 200/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARVGGTEEFAGMLELDYW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) tgtctggattcagtttcagtagctttggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatgatctggtatgatggaactaataaatattatgcagactccgtgaagggccgattcaccatctcgagagacaattccaagaacacactgtttctgctcatggacagcctgacagccgacgacacggctgtctattactgtgcgagagtcgggggaaccgaggagttcgctggtatgttggaacttgactactggggccaggggaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21151 JY8QFUQ01C2MA8 unknown (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 925 90.99 202/222 nt 90.54 201/222 nt 10 7 X 10.7.X [2.17.38.X] null - No rearrangement found in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); gtctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagTcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +21152 JY8QFUQ01BIG5T unproductive Homsap IGHV4-61*02 F 988 94.14 209/222 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD6-6*01 F 2 10 7 X 10.7.X [2.17.38.11] CARNPSYSNSHQHCDY## out-of-frame - gtctctggtgcctccatcaacagtggtagttactactggagttgggttcggcagcccgccgggaagggactggagtggattgggcgtatctacaccagtgggagcaccaactacaacccctccctcaagagtcgagtcgccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctatttttgtgcgagaaatccctcttatagcaattcgcaccagcattgtgactactgggggccagggaaccctggtcaccgtctccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +21153 JY8QFUQ01CLA30 productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame - cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21154 JY8QFUQ01B43GM productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21155 JY8QFUQ01B3LYN productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.16.38.11] CARDLYGADDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaagggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21156 JY8QFUQ01AZTGY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDLTGYSSERNYW in-frame + ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +21157 JY8QFUQ01ASM00 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 881 90.23 194/215 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - caggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +21158 JY8QFUQ01CFART productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacctttaccGaactatggcatgagctgggtccgccaggctccagggaaggggctggagtggggctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21159 JY8QFUQ01AMSFQ productive (see comment) Homsap IGHV1-2*02 F 808 86.85 185/213 nt 85.92 183/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.16.38.11] CARCLWISGTYHFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 45 in the user submitted sequence), (cause frameshift) ttggatatactttcaccgaccattatgtttactggagcgacaggccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21160 JY8QFUQ01B0VVU No results +21161 JY8QFUQ01BAD9H productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 883 89.5 196/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARKRVPGGTFYGDYW in-frame + gcctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21162 JY8QFUQ01CINZT productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21163 JY8QFUQ01BH7ZN productive Homsap IGHV3-7*01 F 953 93.52 202/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRDRFYDSSGYEFGELGDYSDHW in-frame - tctggattcacatttagtaactactggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacntaaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctgtgtgagagatcgattttatgatagtagtggttatgagtttggggaattgggggactactctgaccactggggccagggaacccaggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21164 JY8QFUQ01B7AB1 productive Homsap IGHV3-7*01 F 1045 97.72 214/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [2.17.38.11] CVSSPYFYDSNGYW in-frame - gcctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21165 JY8QFUQ01AF7Y6 productive (see comment) Homsap IGHV3-7*01 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.37.11] CSRLLEEW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +21166 JY8QFUQ01AKHKD productive (see comment) Homsap IGHV4-34*10 F 809 86.51 186/215 nt 85.58 184/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GAA' (3 nucleotides at position 58 to 60 in the user submitted sequence), (do not cause frameshift); tgtctggtgagtccttcactaattactGactggagctggatccgccagtcccccaggGAAaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21167 JY8QFUQ01ARKWX productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21168 JY8QFUQ01A6Z83 productive (see comment) Homsap IGHV3-33*03 F 905 90.83 198/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARSDLSMVRDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 15 to 16 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); gtctgggattcaccCTtgcagtaTcctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatgatttggtatgatggaagccttacatattatgaagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgctgtttctgcaaatgaatagcctgagagtcgaggacacggctctgtattactgtgcgagatccgacctctctatggttagagatcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +21169 JY8QFUQ01C3WEC No results +21170 JY8QFUQ01AD29W productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1022 96.79 211/218 nt 96.33 210/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggagctggagtGgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21171 JY8QFUQ01CNV1W productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 856 88.13 193/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARGGVSGASRWGFDHW in-frame - tctctgggattcaccttcagtagttactggatacactgggtccgccaagctccagggcaggggctggtgtgggtctcacgaattgatagttctgcgcgtctcatagcctacgcggactccgtgaagggacgattcaccgtctccagagacaacgccaagaacacggtgtatcttcaaatgaacagtctgagagccgacgacacggctatttattactgtgcaagagggggggtcagtggggcctccaggtgggggtttgaccactggggccagggagccctggtcaccgtcttctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21172 JY8QFUQ01BYIX2 productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21173 JY8QFUQ01C0EBJ unknown (see comment) Homsap IGHV3-7*01 F 909 91.24 198/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found ctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattcccccctcagcctacgatccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21174 JY8QFUQ01DWYBM No results +21175 JY8QFUQ01AQNOF productive (see comment) Homsap IGHV4-4*07 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 210 to 210 in the user submitted sequence), (cause frameshift); tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgCaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtaCtttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21176 JY8QFUQ01COYVI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21177 JY8QFUQ01BH6YQ productive Homsap IGHV4-39*03 F 905 90.78 197/217 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [0.17.38.11] CARSITLTVVVMNDAFDVW in-frame - ccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtcccttaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21178 JY8QFUQ01B3MC1 productive Homsap IGHV3-48*01 F 815 86.24 188/218 nt Homsap IGHJ6*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 1 8 8 8 8.8.8 [1.17.38.11] CVRGAGLDVW in-frame - cctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaggggctggagtgtgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctggacgtctggggccaagggaccacggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21179 JY8QFUQ01BYV54 productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame - ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +21180 JY8QFUQ01CK6WG No results +21181 JY8QFUQ01B5PJY No results +21182 JY8QFUQ01A0I1V No results +21183 JY8QFUQ01DGNJ4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARFGPLTRPDYWG in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 177 to 177 in the user submitted sequence), (cause frameshift); cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaAatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccaggggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21184 JY8QFUQ01A4GJG unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 930 91.03 203/223 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD3-22*01 F 3 8 10 X 8.10.X [1.17.38.11] CATDRPYYKNRCWPTLVLLRYGRFG# out-of-frame + ctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaatcgctgctggccgactctggtattactacggtatggacgttttgggggcccaaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21185 JY8QFUQ01CEQCM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVKGWNYHSATFGFDYW in-frame + ctctggattcacctttagtgactatgccataagctgggtccgccaggctccaggaaaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccattttcagagacaactccaaagacacgctgtatctgcaaatgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaacctttgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21186 JY8QFUQ01BYPG8 unknown (see comment) Homsap IGHV4-61*02 F 893 89.59 198/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaagggggatagtagtggaccctggaatgactactgggggccagggaatcctgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +21187 JY8QFUQ01B1RCH unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRVVLMVHAMS#DFW out-of-frame - tctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcgggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccctgaaccggtgacggtgtcgtggaactcag +21188 JY8QFUQ01BEEWM unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CGKQLGAHKGADY# out-of-frame + ctctggattcacctttagtagttctggcatgtattgggcccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatgccacaaattacgcagactccgtgaagggccggttcaccatctccagagacaactccatgaacacactgtatctgcaaatgaacagcctgggaaccgatgacacggccttatattactgtggaaagcaattgggggcccataaaggggctgactactggggccagggaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21189 JY8QFUQ01AOGKG productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 936 92.63 201/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-8*01 F 3 8 7 15 8.7.15 [2.17.38.11] CTRELRVAAARDGVDIW in-frame - cgcctctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttacttatcctgatggtactacatactatggagactccgtgaggggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttagggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +21190 JY8QFUQ01B17XY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggGggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcacgttccccgaaccggtgacggtgtgcgtggaactca +21191 JY8QFUQ01BF26Z productive Homsap IGHV3-15*06 F (see comment) 750 81.61 182/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 10 9 8.10.9 [1.17.38.11] CQSGCSKTDCW in-frame + Low V-REGION identity (81,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggcttcagtatagatcacgcctacatgacgtggatacgtcaggctccagggaaggggctggagtgggtcggccgtattaagaagaagtctgatggtgggactgcaacctacgctgcgcccctgagaggcagattcgtcatatccagagatgattcaaagaacacactgtttctggaaatgaacgaccttaaaatcgacgacacaggcgtctattactgccaatcgggttgtagcaagaccgactgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21192 JY8QFUQ01CMXUF unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 93.72 209/223 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CTTGGGTNYY## out-of-frame + in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'A' (1 nucleotides at position 197 to 197 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaAaaaaatatgctgtatctgcaattgaacagcctgaaAaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21193 JY8QFUQ01BZKEG productive Homsap IGHV3-7*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + ctctagattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccc +21194 JY8QFUQ01A1QA1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 784 84.47 185/219 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [2.17.38.11] CARDSGSSEYTRYDAQDVW in-frame - Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctgggattcagcttaagttcttatggcatgaactgggtccgccaggctccatggggggggctggagtgggtctcattcattaacagtattagtagttataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgatattgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21195 JY8QFUQ01AFVGX unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 889 89.19 198/222 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 3 10 7 X 10.7.X [2.17.38.11] CVRHHYGGSLN#FKYW out-of-frame - stop codons gtctccggtgcctccatcagtagtaatagtcactactgggcctggatccgccagtccccagggaaggtcctggagtggattgggagtctctattatactgggagcaccctctacaacccgtccctcaagagtcgactcaccacatctgtggacacgtccaagaatctgttttccctgaacctgagtgctgtgaccgccgcagacacggctgtatattactgtgtgagacaccactacggtggttctctgaatttttaagtactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21196 JY8QFUQ01DVNY6 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CASLNTHSGPGAERSAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'C' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); cctctggatttaccttcagtctctatagaatgaactgggtccCgccaggctccagggaagggactggagtgggtctcatccattactagtaccagtagttacatttattatgcagacccagtgaagggccgattcaccatctccagagacaacgccaagaactcattatatctccatatgaacagcctgagagtcgaggacacggctatatattattgtgcgagtctgaacacgcactcgggaccgggggccgaaaggtctgcttttgatatctggggccacgggacaatggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +21197 JY8QFUQ01CZ5EI productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21198 JY8QFUQ01AS0OG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame + ctctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctccggtattggtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21199 JY8QFUQ01BIHDR productive Homsap IGHV3-9*01 F 850 88.43 191/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + tctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +21200 JY8QFUQ01AP4T9 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.37.11] CAKDASRYYYNSYCDN## out-of-frame + in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 214 in the user submitted sequence), (cause frameshift) cctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttattttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtagaactc +21201 JY8QFUQ01CPJW6 productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21202 JY8QFUQ01BL9W5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 90.48 190/210 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 7 8 12 7.8.12 [X.17.38.11] CARDRLTISALDYW in-frame - ttcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21203 JY8QFUQ01BYW5H productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F (see comment) 773 83.04 186/224 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 10 13 8.10.13 [1.17.38.11] CSTGGPNGYHSTYPW in-frame + Low V-REGION identity (83,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcgccttcaatatcaagtggatgagttgggtccgccaggctccggggaaggggcttgagtgggtcggccgcatcaagagcagcgctgatggtgcgacaacagacaccattgagcgcgtgagagacagattcaccatctcaagagatgactcaaaaaatacactgtacttgcacatgaccagcctgagaaccgaggacacaggcatgtattattgttccacaggcgggccaaatggatatcactccacatatccctggggcccggggacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21204 JY8QFUQ01AAWLL unknown (see comment) Homsap IGHV1-8*01 F (see comment) 768 84.58 181/214 nt 8 8 X 8.8.X [0.17.38.X] null + No rearrangement found Low V-REGION identity (84,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cggatacaccttcagcagttatgatatcaactgggtgcgacaggccactggacgagggcctgaatggatggggtggatgagccctagcggtggtcatgcaaactatgcccagagattccagggcagaatcaccatgaccagggacacctccacaagcacagccttcttggaactaaacagcctgaaacttgaggatacagccatatattattgtgcgcgaggatccctcgaccaaggtggcctcccccaattntggggccagggcaccctgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtccatcgcctgcctggtccagggcttcttcc +21205 JY8QFUQ01DIQG3 productive (see comment) Homsap IGHV3-9*01 F 861 88.18 194/220 nt 86.82 191/220 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [2.17.38.11] CARTYGDHDGMDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 171 to 171 in the user submitted sequence), (cause frameshift); agtctctggattcaccttTtgacgactatggcatgcactgggtccggcAaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatCttttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21206 JY8QFUQ01C1YXJ productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 997 96.26 206/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFYYW in-frame - tggatacaccttcaccagctactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggnggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagacttttactactggggccagggaaccctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21207 JY8QFUQ01B3VYC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGHSYYVSSGPDYW in-frame + cctcggaattctccgtcagtgacagtcacatgagttgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcacgacccagccagatggaacgctggtcgtcgcatgcctggtccagggcttcttcccccag +21208 JY8QFUQ01BIKYR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21209 JY8QFUQ01CBFR4 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 953 91.52 205/224 nt 90.18 202/224 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD2-21*01 F 2 8 10 8 8.10.8 [1.17.38.11] CTSNSWLDRW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 164 to 164 in the user submitted sequence), (cause frameshift); cctctggattcgctttcagtaatgcctggatgagttgggtccgccaggctccagggaaGggggctggagtgggttgGgccgtattaaaaaggcagttgatggtgggccaacagactacgctgcacccgtcaaaggcagattcaccatctcaagagatgattcaAaaaaatacgttgtatctgcaaatgaacagcctgaaaagcgacgacacaggcatttattactgcacctcgaattcctggctcgaccgctggggccagggaacccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcaccagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaaactcagg +21210 JY8QFUQ01AV2A1 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 751 82.95 180/217 nt 82.49 179/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame - stop codons Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); cctctgactcaacattggcaactatgacatgacctgggtccgccaggctcctgggaaggggctggagtgggtctcaagtattggaactactgagggtagctcatattatgcagactccgtgaagggccggttcaccatctccagagacaactcccagactacgcngTtttttggagatgagcagcctgagagacgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccgagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +21211 JY8QFUQ01AT3GQ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21212 JY8QFUQ01DAT9F productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1006 95.05 211/222 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 2 10 7 12 10.7.12 [2.17.38.11] CVRHRRLELLPDYW in-frame - gtctctggtgactccatcagcagtaatagtttctactggggctggatccgccagcccccagggaaggggctggagtggattgggaatatctattatagtgggagcacctactacaacccgtccctcgagagccgagtcaccatatccgtagatacatccaggaaccagttctccctgaagctgaggtttgtgaccgccgcagacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21213 JY8QFUQ01DH0FR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 931 92.59 200/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21214 JY8QFUQ01DMIT2 unproductive Homsap IGHV1-3*01 F 966 94.86 203/214 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [0.17.38.11] CARWNNDLDY## out-of-frame + tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattgggggccagggaaccctagtcactgtctcttcagcatccccctgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttcccccca +21215 JY8QFUQ01AL791 productive Homsap IGHV3-48*01 F 1085 100.0 218/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgcggaactc +21216 JY8QFUQ01BHSGX No results +21217 JY8QFUQ01AY4W6 No results +21218 JY8QFUQ01CVPJD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 995 95.41 208/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame - cctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21219 JY8QFUQ01DLNG7 No results +21220 JY8QFUQ01BYC2V productive Homsap IGHV3-11*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame + ctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgcacagcacccccaagatgggaacgtggtcatcgccctgcctggtccagggcttcttcccc +21221 JY8QFUQ01CH2C7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatagtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +21222 JY8QFUQ01B3ITN unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21223 JY8QFUQ01BP7FM productive Homsap IGHV3-30*01 F 1053 98.62 214/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-16*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARDRFGDYILGYYFYGMDVW in-frame - ctctggattcaccttcagtagctatgctatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcatttgatggaggtaataaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgagagaccgattcggtgactacattttagggtactacttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21224 JY8QFUQ01AUH73 productive Homsap IGHV3-9*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKDRGSSSKYYFDYW in-frame + cctctggattcacctttgatgattatgtcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggggaagtgctcatatacactatgcggactctgtgaaggaccggttcaccatctccagagacaacgccatgaactccctttatttgcaaatggacagtctgagagctgacgactcggccttgtattactgtgtaaaagatcggggtagcagttccaagtattactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +21225 JY8QFUQ01BS5QC productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 888 89.55 197/220 nt 89.09 196/220 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 10 7 16 10.7.16 [1.16.38.11] CTNDFSMAVRATHAFHVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtgactccattggtagtagtgcttactactggggctgggtccgccagccccagggaaggggctcgaatggatagggaatatttactatggtggcagcacctactacaacccgtccctcaagaatcgagtcaccatatcggtagacacgtccaagaaccagctcttcctggagctgacctctgtgaccgccgcagacacggctctttattactgtacgaacgacttttcaatggcggtacgtgctacgcatgctttccatgtctggggccaagggacaatggtcgccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21226 JY8QFUQ01ATCXQ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame + gcctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21227 JY8QFUQ01B9OPE unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21228 JY8QFUQ01CHP04 unproductive Homsap IGHV3-74*03 F (see comment) 712 80.82 177/219 nt 79.45 174/219 nt Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [2.17.38.11] CVRGTTGWRGVDY## out-of-frame - Low V-REGION identity (80,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); gcctctggaGttcaacgtcagtggatactggatgcactgGggtccgccaagtgccagGggaaggggctggtatgggtctctaggctttcggatgatgaaattactataacttacgcggactttgtggagggccgattcaccatctccagagacaacgccaggaacgaggtctatctgcaaatgaatgatttgagagtcgacgatacggctgtatacttttgtgtgaggggaaccactggctggaggggggttgactactgggggccaaggcgccctcgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +21229 JY8QFUQ01B3TCU No results +21230 JY8QFUQ01CV5AS productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 806 85.78 187/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21231 JY8QFUQ01AQU2C productive (see comment) Homsap IGHV3-48*01 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaAaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21232 JY8QFUQ01BTMWH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgttgcgtggaactcag +21233 JY8QFUQ01AHUQ7 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD6-25*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKSPLSV#W out-of-frame - ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21234 JY8QFUQ01CINEB No results +21235 JY8QFUQ01DIZB4 productive (see comment) Homsap IGHV3-33*03 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift) cgtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21236 JY8QFUQ01C0N7A unproductive Homsap IGHV3-48*01 F 1090 100.0 219/219 nt 98.63 216/219 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [2.16.38.11] CASRLRSSGGY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) agcctctggattcaccttcagtagctatagcatgaactgggtccGgccaggctccagggaagggctggagtgggtttcatGacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21237 JY8QFUQ01A5U65 unproductive (see comment) Homsap IGHV3-7*01 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CVSSPYFL***W#YW out-of-frame + stop codons tctggattcaccttcagtgactactacatgtcgtggatccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtattttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +21238 JY8QFUQ01DPXQH No results +21239 JY8QFUQ01CQXUW productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 971 94.88 204/215 nt 93.95 202/215 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARYRGYQSYFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtCagttactactggagctggatccggcagccccacgggaagggactggagtggattgggtatCatctcttacagtgggggcaccaattacaatccctccctcaagagtcgagtcgccatatcaggagacacggccaagaaccagttctccctgaagctgaactctgcgaccgctgcggacacggccgtgtattactgtgcgcggtataggggttaccagagctactttgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21240 JY8QFUQ01B7GYB productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 900 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [1.17.38.11] CNTDLGGSWYTFYSDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 59 of V-REGION: 6 nucleotides (from position 89 in the user submitted sequence), (do not cause frameshift) ctctggatacactgtcataaatgcctggatgagttgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaggtgatggtgtgacaacagaatacgctgcatccgtgaaaggcagattcaccatcacaagagatgactcaaggaacacgttgtatctacaaatgaacagcctgaaaaccgaggacacagccatatattattgcaacacagatctgggcgggagttggtacaccttctattctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21241 JY8QFUQ01BFQMJ productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 987 95.77 204/213 nt 94.84 202/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 3 8 7 11 8.7.11 [0.17.38.11] CARGQQLRDFYYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 90 in the user submitted sequence), (cause frameshift) tggatacaccttcaccagctactatatacactggGgtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtgnggtgccacaagntacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagacttttactactggggccagggaaccctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21242 JY8QFUQ01BYNNU unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 455 77.42 120/155 nt 76.13 118/155 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD4-23*01 ORF 3 X 8 X X.8.X [X.5.38.11] CAREEWDNGGFGA## out-of-frame + Low V-REGION identity (77,42% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'AG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); cctctggattcgcacgtattgggattgttggtggtaaaaGcagactacgcggacgccgtaaaAGggccgttttcaccatctccagagacaacacaaggaagactctgtatctacaaatgaacagtctgcgacccgaggacacggcggtgtattactgtgccagagaggaatgggacaacggtggtttcggggcctggggcccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +21243 JY8QFUQ01BQ9K4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 809 86.51 186/215 nt 86.05 185/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.16.38.11] CVKDISRSGCFEYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) tctggattccagtttagcaactatgccatgagctgggtccgtcaggctcctggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21244 JY8QFUQ01CNW9W productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +21245 JY8QFUQ01AA3GK productive (see comment) Homsap IGHV3-7*01 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) tctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21246 JY8QFUQ01BKLR9 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 8 8 20 8.8.20 [1.17.38.11] CTRTQFDPDYGDYETGYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cggctggattcaacttccgatcttatgccatgtactgggtccgccaggccccaggcaaggGggctggactgggtggcagttatttggcatgatggcagtaatcaatactatgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacattgtttctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtacgaggacgcaatttgaccctgactacggtgactacgagacggggtacggtatggacgtctggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgccatggcctggtccagggcttcttccc +21247 JY8QFUQ01BYMEG productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 931 92.59 200/216 nt 91.67 198/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'TG' (2 nucleotides at position 35 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tccggattcagtttcagtacttataacatgaattTGgggtccgccaggctccagggaaggGggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21248 JY8QFUQ01A65A5 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1078 98.65 219/222 nt 98.2 218/222 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD2-2*01 F 3 10 7 X 10.7.X [2.17.38.11] CARSRTFYGSANY## out-of-frame + in FR2-IMGT at codon 46 of V-REGION: 'CA' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccCAgggaagggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21249 JY8QFUQ01AFJ98 No results +21250 JY8QFUQ01CVI77 productive (see comment) Homsap IGHV4-4*07 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD4-17*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARDLPTVTTGALDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'GA' (2 nucleotides at position 72 to 73 in the user submitted sequence), (cause frameshift); tctctggtggctccttcagtaattaccactggagctggatccggaagcccgccgggaaggaactggagtggGAttggggcgtatccatcacagtgggctcaccaactccaacccctccctcaagaatcgagtcgtcgtgtcagtggatacgtccaagaatcagttgtccctggagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagatcttcctacggtgactactggggctcttgatatctggggccaagggacaatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21251 JY8QFUQ01C54HB productive (see comment) Homsap IGHV4-61*02 F 820 86.3 189/219 nt 84.93 186/219 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 10 7 18 10.7.18 [1.17.37.11] CAREDYYGSGSYGRAWFDSW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 117 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 125 in the user submitted sequence), (cause frameshift) tctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtggGgggtgtcgactacaaccctccctcagggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagaggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21252 JY8QFUQ01B56NJ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 808 85.14 189/222 nt 84.23 187/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [2.17.38.11] CARRWARQRLVMDYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'GA' (2 nucleotides at position 70 to 71 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); gtctctggtgactccatcagtagtactcattactattggggctggatccggcagccccccagggaggggGActggagtGgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +21253 JY8QFUQ01C76ZC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +21254 JY8QFUQ01A4ZI3 unknown (see comment) Homsap IGHV4-61*02 F (see comment) 523 70.78 155/219 nt 69.86 153/219 nt 10 7 X 10.7.X [2.17.37.X] null + No rearrangement found Low V-REGION identity (70,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'TCC' (3 nucleotides at position 146 to 148 in the user submitted sequence), (do not cause frameshift); gtctctggtggccCccatcagcagtggtacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccacctacaatccctccctcaagagtcgaatcaccgtcTCCtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +21255 JY8QFUQ01CLS9T No results +21256 JY8QFUQ01C2M6O productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccCccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +21257 JY8QFUQ01DURSH productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); tctggattcaccttCcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtaGgtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21258 JY8QFUQ01AZKVO productive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 1007 96.74 208/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [0.17.38.11] CASVVGATMDDAFDVW in-frame - Other possibilities: Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) ctggaggcaccttcagcagctatactttcagctgggtgcgacaggcccctggacaagggcttgagtggatgggagggattatccctatgtttggtacagcaaactacgcacagaagttccaggacagagtcacgattaccgcggacgagtccacgagcacagcctacctggagctgagcagcctgagatctgaggacacggccgtgtattactgtgcgagtgtggtgggagccactatggatgatgcttttgatgtttggggccaagggggcagtggtcaccgtctcttcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +21259 JY8QFUQ01CBYCK No results +21260 JY8QFUQ01CDVN4 productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +21261 JY8QFUQ01CN25Y productive (see comment) Homsap IGHV3-66*02 F 903 91.59 196/214 nt 91.12 195/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 7 13 8.7.13 [1.17.38.11] CASVGVGATVAFQYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'GA' (2 nucleotides at position 91 to 92 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcagtgatagttacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcgattatttataggggGAgggtaccacatattatgccgactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctatatcttcaaatgaacaccctgagaggtgaggacacggctctatattactgtgcgagcgtcggagtgggagctacagtcgcctttcaatactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21262 JY8QFUQ01CME13 productive Homsap IGHV4-39*02 F 956 92.31 204/221 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [1.17.38.11] CARRYSWNYERFDPW in-frame + tctctggtgactccatcagtactaataattactactgggcctggatccgccagcccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggctgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21263 JY8QFUQ01CB9IS unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'TC' (2 nucleotides at position 14 to 15 in the user submitted sequence), (cause frameshift); attctggattcagTCctagccgactttttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21264 JY8QFUQ01CTZS3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-8*02 F 2 8 8 20 8.8.20 [1.17.38.11] CARDLWLCSGGECYHRGGFENW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); tctgggttcaccttcagtaactcctggatgcactgggtccgccaagctccagggaaggggccggagtgggtctcacgtattaatagtgatgggagtaatacaatctacgcggactccgtgaagggccgactcaccatctccagagacaacgccaaaaaTcacggtgtatctgcaattgaacagtctgagagccgaggacacggctgtgtactactgtgcaagagatctgtggctttgtagtggtggtgaatgctatcatcggggtggttttgagaactggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +21265 JY8QFUQ01BG43D productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 973 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggGggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21266 JY8QFUQ01DM7BI No results +21267 JY8QFUQ01CHG8T productive (see comment) Homsap IGHV3-7*03 F 864 88.94 193/217 nt 88.02 191/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 41 of V-REGION: 'TG' (2 nucleotides at position 36 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); ctctggattcacgtttagagactattggatgaggtTGggtccggccaggctcctgggaGgggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgcagggccgattcaccatctccagagacaacgacaacaacgtcctgtatctgcaaatgaacagtttgagacccgaggacacggccttgtatcgctgtgcgagagaggtttcggacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21268 JY8QFUQ01CZW8Y productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame + tctctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21269 JY8QFUQ01BZ46F productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD6-6*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARDRTPYYYHYGMDVW in-frame + tctctggtggctccatcactagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagagatagaaccccgtactactaccactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +21270 JY8QFUQ01AA0WQ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1046 97.29 215/221 nt 95.93 212/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 176 to 176 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactgGgggctggatccgccagcCccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccCctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +21271 JY8QFUQ01BSHS6 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + stop codons ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggctgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgggaactcag +21272 JY8QFUQ01AVOZ8 unproductive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [1.17.38.11] CVRG*RWC*FLAKWTTG in-frame - stop codons in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggattcacctttagcagacattggatgacctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaAaacaagatggaagtcagagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgtgagggggtagagatggtgttaatttttggcgaaatggactactgggggccagggaatcctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21273 JY8QFUQ01DDNP8 No results +21274 JY8QFUQ01A8FSV productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 813 86.92 186/214 nt 86.45 185/214 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [0.17.38.11] CARGFSAWGQDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift); tggatttatcttcagtgattatagcatgaattGgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +21275 JY8QFUQ01DKLDC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21276 JY8QFUQ01C10NV No results +21277 JY8QFUQ01APZM5 unproductive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 2 10 9 X 10.9.X [1.17.38.11] CTRGSSRWGEI**ELL*A#DFW out-of-frame - stop codons tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgctggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21278 JY8QFUQ01CPQ7T productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + cctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +21279 JY8QFUQ01CLIFW No results +21280 JY8QFUQ01DCX1U No results +21281 JY8QFUQ01A4HIU productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 809 86.51 186/215 nt 85.58 184/215 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 3 8 8 16 8.8.16 [1.17.37.11] CARDLPAMGKYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 2 nucleotides (from position 156 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 167 in the user submitted sequence), (cause frameshift) gctctggatttatgctcaggacttatgacatgaattgggtccgccaggctccagggaaggggctggagtgggtcgcatccattagtagaaatacagattacacatattacgcagactcagtgaggggccgattcaccatctccagagacaacgccgaaatcactattttgcaaatgagcagtctgagagccgaggacacggctctctatttctgtgcgagagatttgccggctatgggaaagtactactatggcatggacgtctggggccaagggaccacggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21282 JY8QFUQ01C0DJC unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt 94.95 207/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaGggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgattctggggccaagggacagtggtaatgtctcctagcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +21283 JY8QFUQ01CO9Q7 productive Homsap IGHV3-30*01 F 927 92.17 200/217 nt Homsap IGHJ6*02 F (see comment) 229 85.48 53/62 nt Homsap IGHD2-15*01 F 2 8 8 21 8.8.21 [1.17.38.11] CARVGCRGVSCYSSYHYSAMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagcacctatactatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttatgtcatctgatggaagtgataaatactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaataccttgtatctgcaattaaatagcctgagaggtgacgacacggctgtgtattactgtgcgagagtgggttgtcgtggtgttagctgctactcttcctaccattactccgcaatggacgtctggggccagggggccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +21284 JY8QFUQ01CV7FV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21285 JY8QFUQ01B0DOB productive Homsap IGHV3-48*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-3*01 F 3 8 8 20 8.8.20 [1.17.38.11] CARARRTISGVVFIEHYGMDVW in-frame + ctctggattcaccttcaggacccatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcattcattagtagtagtagtggtaccatattttatgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactttatctgcaaatgaacagcctgagagacgaggatgcggctgtgtattactgtgcgagagcccgtaggacgatttctggagtggtttttattgagcactacggtatggacgtctggggcccagggaccacggtctccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +21286 JY8QFUQ01A0Q68 unproductive Homsap IGHV3-72*01 F 967 92.44 208/225 nt 91.56 206/225 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD7-27*01 F 2 8 10 X 8.10.X [2.17.38.11] CVRDPFSSRG##W out-of-frame - in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 130 to 130 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'C' (1 nucleotides at position 197 to 197 in the user submitted sequence), (cause frameshift); ggctctggattcatcctcagtgactaccacatggagtgggtccgccaggctccagggaaggggctggagtgggttggccgtagtagaaagaaagctaatagttacagtacagaatatgccgcgtctgtgCaaaggcagattctccatttcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgCaaaatcgacgacacggccgtgtattattgtgtcagagaccccttctcaagtcgggggccactggggccagggaaacctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +21287 JY8QFUQ01C8DBD No results +21288 JY8QFUQ01BGN76 unproductive (see comment) Homsap IGHV3-11*01 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRYLGQLLLL*RSGRL# out-of-frame - stop codons Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcaccttcactgactactacatgacctggatccgccaggctccagggaAaggggctggagtgggtttcacacattagtagtggtggtagaaccattgcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtttctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgagatatttggggcagctactattactataacggtctggacgtctggggggcaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21289 JY8QFUQ01BNC57 productive Homsap IGHV1-2*02 F 786 85.51 183/214 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-16*02 F 2 8 8 15 8.8.15 [0.17.38.11] CARHYCDTNGVCDFDIW in-frame - tggatacagcttcaccgactttcatattcattgggtgcgacaggaccctggacaagggcttgagtggatggggtggaccaaccctaaaaatggcggcacgttcattacgctgaagtttcagggcagggtcactatgtccagggacacgtccatgaccacagtctatatggaaatgagcaggctgagatctgacgacacggccatttattactgtgcgagacattattgtgacaccaacggcgtctgtgattttgatatctggggccaggggacaaaggtcatcgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21290 JY8QFUQ01B9RRQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21291 JY8QFUQ01BYGEB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggGggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21292 JY8QFUQ01BY5VZ productive Homsap IGHV3-7*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame - cctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag +21293 JY8QFUQ01DCKYB unproductive (see comment) Homsap IGHV3-66*02 F 931 92.59 200/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [2.17.38.11] CALTYQRRDKYDSSGYY#FDYW out-of-frame - stop codons in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'AGG' (3 nucleotides at position 80 to 82 in the user submitted sequence), (do not cause frameshift); gcctctggattcaccgtcagtagtaagcacatgaactTggggccgccaggctccagggaaggggctggagtgggtctcaAGGttactttacagcggtggtagtatatactacccagactccgtgaagggccgattcaccatctccagagacaactccaagaccaccctgtatcttcaaatgaacagcctgagagctgaggacacggctgtatattactgtgcgctaacctaccagaggcgggataagtatgatagtagtggttattacttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +21294 JY8QFUQ01BZYBZ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARHRAGDSNHFDDW in-frame - ttctggttacgattttgccagacattggatcggctgggtgcgccagacgcccgataaaggcctggagtggatggggatcatctatcctggtgactctgatactagatacagcacgtccttccaaggccaggtcactatctctgccgacaagtccatcagcaccgtctacttgcagtggaatagactgcagacctcggacagcgccatatactactgtgcgagacaccgggcgggggactccaaccactttgacgactggggcccgggaacccaggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21295 JY8QFUQ01CCQ32 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 920 90.95 201/221 nt 90.5 200/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARGSWCTNGVCLLDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); tctctggtggctctgtcagcagtaacgttcacttttggggctgggtccgccagcccccagggaaggggctggagtggattgggagtgtctatcatagtggaagcacctactacaaccCcgtcactcaagagtccagtcaccatctccgttgacacgtccgagaaccaggtctccctgaagctgagctctgtgaccgccgcagacacggctgtgtactactgtgcgaggggttcatggtgtactaatggtgtttgccttcttgactattggggccagggaattctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgctggtccaggcttcttccc +21296 JY8QFUQ01CB4CO unknown (see comment) Homsap IGHV1-18*02 (F) (see comment) 492 71.64 144/201 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [X.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (71,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggcctggagtggatgggatgggtcagcggttataatgataaatccaactatgcacagaagttcaaagacagaattatcatgaccacagacatatcaacgagctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21297 JY8QFUQ01C2M7Y productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatttccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21298 JY8QFUQ01BE4AN productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 907 92.02 196/213 nt 91.08 194/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 2 9 7 11 9.7.11 [X.17.38.11] CARASTLRYLDRW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ggtggctccatcagcagtgataattggtggagttgggtccgccagcccccaCgggaagggactggaatggattgGgggaaatatatcatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacaagtccaagagtcaattcttcctggagctgaggtctgtgaccgccgcggacacggccgtatattattgtgcgagagcctccacactacgatatcttgaccgctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21299 JY8QFUQ01CQYMO productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21300 JY8QFUQ01AYQIF productive (see comment) Homsap IGHV3-7*01 F 926 92.56 199/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 7 8 6 7.8.6 [1.17.38.11] CVKSIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) tctggattcacttttagcagttttggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaAagtgggatggaagtgataaaaagtatatggactttgtgaagggccgattcaccatctccagagacaacgccaagaattcactatatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtgaaaagcattgactcctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21301 JY8QFUQ01CVIQ7 No results +21302 JY8QFUQ01CUQ02 productive Homsap IGHV3-48*02 F 891 90.32 196/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [1.17.38.11] CARGQKWLQVLRWFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +21303 JY8QFUQ01BSHHE productive Homsap IGHV3-7*01 F 955 93.15 204/219 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSDFYSTGHW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ggctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21304 JY8QFUQ01BYEW8 productive Homsap IGHV3-30*01 F 977 94.5 206/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggctcaaggactacttccccggaaccggtgacggtgtcgtggaactca +21305 JY8QFUQ01CS6TS productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21306 JY8QFUQ01BW0VC productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 959 93.58 204/218 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 14 8.8.14 [1.17.38.11] CATDRKYSGVRGDDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcaggaactatgctatgcactgggtccgccaggctcctggcaaggggctagaatgggtggcttttatatcatatgatggaagtagtcaatactacgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacactttatctgcaaatgaacagcctgagaggtgacgacacggctgtgttttactgtgcgacggaccggaaatatagtggtgtacgaggcgatgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21307 JY8QFUQ01B8JXV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21308 JY8QFUQ01BVHS5 productive (see comment) Homsap IGHV3-69-1*02 P 919 93.33 196/210 nt 92.38 194/210 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-20*01 F 3 8 7 10 8.7.10 [1.16.38.11] CARDDKWAFDYW in-frame - Potentially, because of detected insertion/deletion however the closest V is a pseudogene in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 3 nucleotides (from position 76 in the user submitted sequence), (do not cause frameshift) tctggattcaccttcagtgactacagcatgaactGgggtccgccaggctccagggcaggggctggagtgggtctcatatagtcgcggaagaaccacatactacgcagactctgtgcagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgacagccgaggacacggctgtttattactgtgcgagagatgataagtgggcatttgactactggggccagggaaccctggtcgtcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21309 JY8QFUQ01BM4S8 unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 96 55.91 52/93 nt 54.84 51/93 nt 8 X X 8.X.X [17.6.X.X] null - No rearrangement found in FR1-IMGT, from codon 17 of V-REGION: 24 nucleotides (from position 107 in the user submitted sequence), (do not cause frameshift) gggggaagaagccctggaccaggcaggcgatgaccacgttcccatctggctgggtgctgcagaggctcagcgggaagaccttgggggctggtcggggatgctgggggccgccggatccaactccagtagtaaccagtcatggagccaccagaga +21310 JY8QFUQ01DMLBM productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 881 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); gtttcggggttcaccgtcagtagcaagtacatnacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag +21311 JY8QFUQ01B1BO5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 995 95.41 208/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame - cctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21312 JY8QFUQ01C39IC productive Homsap IGHV3-48*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTRQTGNYYYFGVDVW in-frame - ctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +21313 JY8QFUQ01CS9LF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + tctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21314 JY8QFUQ01C7L9L productive Homsap IGHV3-7*01 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21315 JY8QFUQ01BJJ22 No results +21316 JY8QFUQ01AGZC5 productive Homsap IGHV3-48*03 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARESWWSGFYGWYDPW in-frame + ctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +21317 JY8QFUQ01AFOO8 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 907 90.09 200/222 nt 89.19 198/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARHSRLVRYFEFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaGggggctggagtggattCgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +21318 JY8QFUQ01AC68M unproductive (see comment) Homsap IGHV1-2*02 F 813 86.92 186/214 nt 86.45 185/214 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [0.16.38.11] CARCLWISGTYHFDFL# out-of-frame - stop codons in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) ttggatatactttcaccgaccattatgtttactggatgcgacaggccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgattttctgggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21319 JY8QFUQ01ADEK7 unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*03 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ6*02 F (see comment) 157 72.58 45/62 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDQRDYDYIYYY#GMDLW out-of-frame + Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 178 to 178 in the user submitted sequence), (cause frameshift); ctctggattctccctcaggaatcatgctatgcactgggtccgccagactccaggcaagggactcgagtgggtggcagttatctcatttaatggacgaaggaagtattatgcagacttcgtgaagggccgattcaccatcaccagggacaattcccagaacactctgtctctgcaaatTgaatagcctgggaactgaggacacggctgtctattactgtgcgagagatcagcgtgactacgattacatctactattacggggatggacctctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +21320 JY8QFUQ01B9UZ4 productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 11 8.8.11 [0.17.38.11] CARVIRTNWLDPW in-frame - tggttacacctttactacctatggcatcagctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggaaatacaaactctgcacagaagttccaggacagagtcaccctgaccacagacacatccacgagcacagcctacatggagctgaggaacctgagatctgacgacacggccgtgtattactgtgcgagagtaattcggaccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21321 JY8QFUQ01BLYFX productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21322 JY8QFUQ01A1U87 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21323 JY8QFUQ01B35H5 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21324 JY8QFUQ01B2P9A productive (see comment) Homsap IGHV3-7*02 F 913 91.67 198/216 nt 90.74 196/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 7 8 14 7.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) ctctagattcacctttaatgttactggatgagttgggtccgccaggctccaggaaaagGggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21325 JY8QFUQ01A4ENF productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'A' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaAaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21326 JY8QFUQ01DIY92 productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21327 JY8QFUQ01BUWWW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21328 JY8QFUQ01AT51K productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 876 90.19 193/214 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [0.17.38.11] CARGMATAESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) tggaatcaccttcagcagacatagcatgaactgggtccgccaggctccagggaaggggctggaatgggttgtatatattagcggtagcagcagtgccatattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21329 JY8QFUQ01BQ499 productive Homsap IGHV1-3*01 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21330 JY8QFUQ01A4GNO No results +21331 JY8QFUQ01ALGGP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + cctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa +21332 JY8QFUQ01CJGZE unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1003 94.22 212/225 nt 93.78 211/225 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [2.17.38.11] CTTGGGTNYY## out-of-frame - in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift); acctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcCaaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactgggggccagggaaccctggttaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21333 JY8QFUQ01B2XE6 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F or Homsap IGHV4-55*03 P 815 86.24 188/218 nt 85.32 186/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 2 9 7 15 9.7.15 [1.17.38.11] CTSREHAFSGQFTGDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'TCA' (3 nucleotides at position 25 to 27 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tgtctggtgtctccgtcaccagcgTCAgtcactggtggacctgggtccgccagcCccccagggaagggactggagtggattggagaaatctattattatggcatcaccaatttcaacccgtccctcaagagtcgaatcagcatgtcagtggacgagtccaagaaccagttctccctgagactgacttctgttaccgccgcggacacggccgtttattattgtacgagtcgcgaacatgcttttagtggtcaattcacgggtgactactggggccagggaaccctgatgaccgtcacctcagcctccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagacgcacagcggcccctggggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21334 JY8QFUQ01BVCQ0 unknown (see comment) Homsap IGHV2-5*02 F 1134 96.31 235/244 nt 10 7 X 10.7.X [9.17.38.X] null - No rearrangement found gaccctcacgctgacctgcaccttctctgggttctcactcaccactactggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcagtcattttttgggatgatgatgagcgccacagcccatctctgaggagaaggctcaccatcaccaaggacatctccaaaaaccaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattactgtgcanacttttcggtgactacccccatatggtatggacgtctgggggccaaggggaccacggtcaccgtctccctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21335 JY8QFUQ01AJPAA No results +21336 JY8QFUQ01A79UO productive Homsap IGHV3-48*01 F 867 89.72 192/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [0.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame - tggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21337 JY8QFUQ01C07L6 unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CVRGGLRWRPPDITTT#YGLDVW out-of-frame - ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagagggggactacggtggcgacccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctcccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21338 JY8QFUQ01BZLF1 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 993 96.26 206/214 nt 95.79 205/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-3*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARGYDFWSTYRGYNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'CTA' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggCTAtcatcatcttacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgaactctgtgaccgctgcggacacggccgtgtattattgtgcgagaggttacgatttttggagtacatatcgtgggtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21339 JY8QFUQ01A1G6Q unproductive Homsap IGHV3-7*01 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [2.17.38.11] CVRGRDGVKFWRNGLL# out-of-frame - gcctctggattcacctttagcagacattggatgacctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtcagagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgtgaggggtagagatggtgttaaattttggcgaaatggactactgggggccagggaatcctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21340 JY8QFUQ01BWN76 No results +21341 JY8QFUQ01CCLFY No results +21342 JY8QFUQ01B95ZO No results +21343 JY8QFUQ01CCNXP unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKQKHSYGYY#DQW out-of-frame + ctctggattcacgtttaaaacacatgccatgagctgggtccgccaggctccaggaaaggggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaaacatagttatggatactacttgaccagtggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +21344 JY8QFUQ01BXNR5 No results +21345 JY8QFUQ01C67LB productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame - ttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21346 JY8QFUQ01B4XPK productive (see comment) Homsap IGHV2-5*02 F 1165 97.94 238/243 nt 97.53 237/243 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 2 10 7 11 10.7.11 [9.17.38.11] CAHRRIRFGFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); accctcacgctgacctgcaccttctctgggttctcactcagcactggtggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcactcatttattGgggatgatgataagcgctacagcccatctctgaagagcagactcaccatcaccaaggacacgtccaagaaccaggtggtcctcacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacaggaggatacgattcggctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaact +21347 JY8QFUQ01B1H8E productive Homsap IGHV4-61*08 F (see comment) 827 87.44 188/215 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD7-27*01 F 2 8 7 13 8.7.13 [1.17.38.11] CASVRYLGERLFDHW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (8 AA in JY8QFUQ01B1H8E ; 10 AA in Homsap_IGHV4-61*08) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccctcgggggtttcgcctggagttggatccggcagcgcccagggaagggactggagtggattggacatatctctcacattgcggactccaactatgagccctccctcaagagtcgactcaccatgtcagtagacgcgtccaagaaccagatctccctgaaactgacctccgtgaccgctgcggacacggccgtctattactgtgcgagcgtgcgctatctcggagaacggctattcgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +21348 JY8QFUQ01C7TH3 unproductive Homsap IGHV3-66*02 F 918 91.71 199/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 X 8.7.X [2.17.38.11] CAKFGGYWRVEQPHLLF#W out-of-frame + in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); agcctctggattcaccgtcagtagcagcttcatgacttgGggtccgccaggctccaggaaAagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaatttggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21349 JY8QFUQ01CWFJA productive (see comment) Homsap IGHV3-9*01 F (see comment) 779 84.4 184/218 nt 83.94 183/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'A' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggAcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21350 JY8QFUQ01CRUJQ productive Homsap IGHV3-33*03 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTRDIGERYSYW in-frame - cctctggattcaacttcggtgactactacatgaactggatccgccaggctccaggcagggggctggagtgggtggcaattatatggcatgatggaaccaataaatactatgcagactccgtgaagggccgattcaccgtctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgagcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21351 JY8QFUQ01BFSIG unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 163 92.11 35/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found cctctggattcacctttaacagccatgccatgagttgg +21352 JY8QFUQ01CK6XG unknown (see comment) Homsap IGHV1-2*02 F 880 90.61 193/213 nt 89.67 191/213 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [X.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 42 of V-REGION: 'A' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); ggatacaccttcactgactactttatacactgggAtacgccaggcccctggacaaggccctgagtggatggGggtggatcaacgctaacagtggtgccacagagtatgcacagaggtttcagggcagggtcaccatgaccagggacacgtccatcaccacagcctacatggacttgagcagtctgagatctgacgacacggccgtctattattgtgcgagactagtcccccacacgagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21353 JY8QFUQ01DI5CP productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 903 91.59 196/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame + ttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21354 JY8QFUQ01C7LW0 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRQLGFGDLFRFDPW# out-of-frame + in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggGggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +21355 JY8QFUQ01CDTNX productive Homsap IGHV3-30*04 F, or Homsap IGHV3-30-3*03 F 900 90.32 196/217 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDKSAVLGTSELDAFDVW in-frame - ctctggattcaccttcagaagttctgcccttcactgggtccgccaggctccaggcaagggcctggagtgggtggcagtaacatcatatgatggaggtgataaatcctacgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgctatatctgcgaatgactaacctgagacctgaggacacggctgtctattactgcgcgagagacaagtcggcagtgcttggtacgagtgagctggatgcttttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21356 JY8QFUQ01CLMGG productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 921 90.58 202/223 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD2-21*01 F 2 8 10 8 8.10.8 [1.17.38.11] CTSNSWLDRW in-frame - ctctggattctctttcagtaatgcctggatgaattgggtccgccaggctccagggaaggggctggaatgggttggccatattaaaagggaaattgatggtgggataacaaactacgctgcacccgtgaagggcagattctccatcgcaagagatgattcaaagaatatgatgtatttgcaaatgaacagcctgaacaccgaggacacaggcgtgtattactgtacctcaaattcgtggctcgaccgctggggccagggaacccccgtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21357 JY8QFUQ01CJJ9D unproductive (see comment) Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKARIYFLWFGELFP#FDYW out-of-frame - stop codons cctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctattttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21358 JY8QFUQ01CVGC8 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 764 84.19 181/215 nt 83.72 180/215 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CAREKRFGPPH#GMDVW out-of-frame + Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 189 to 189 in the user submitted sequence), (cause frameshift); gttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaggggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagcCcccgaggacacggccgtctactactgtgcgagagaaaagaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtccaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21359 JY8QFUQ01CEJ1C productive Homsap IGHV3-7*01 F 943 93.02 200/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [0.17.38.11] CVRDRFYDSSGYEFGELGDYSDHW in-frame - ctggattcacatttagtaactactggatgagctgggtccgccaggntccagggaaggggctggagtgggtggccaacntaaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctgtgtgagagatcgattttatgatagtagtggttatgagtttggggaattgggggactactctgaccactggggccagggaacccaggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21360 JY8QFUQ01CRULS productive (see comment) Homsap IGHV4-61*02 F 888 89.55 197/220 nt 88.64 195/220 nt Homsap IGHJ4*01 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-22*01 F 3 10 7 11 10.7.11 [1.16.38.11] CARAREFLTFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtgcctccatcaacaatgatactttctactggaactggatccggcagccgccgggaagggactgcagtggattgggcgtCatgtatgccagtgggaccactaactacaacccctccctcaagagtcgagtcaccatgtcagtagtcacgtcaaagaatcaattttccctgaagttgagttctgtgaccgccgcagacacggccatttactactgtgcgagggcccgagagtttctcacctttgactcctggggccaaggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21361 JY8QFUQ01CH1SK unproductive (see comment) Homsap IGHV3-48*01 F 896 90.37 197/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CARESTWEFYS#DSW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattcagtttcagtgactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagttctagtagtaccctatattatgcagactctgtgaagggccgattcaccgtctccagagacaatgacaagagttctctgtatctgcaaatgaccggcctgagagccgaagacacggcgacttattactgtgcgagagagtcgacgtgggaattttactcctgactcctggggcccggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21362 JY8QFUQ01B63GH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21363 JY8QFUQ01C9AAJ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKEQEPHGHYVGTDYW in-frame - cgtctggattcaccttcagtagctacggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagagccgattcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggccgtgtattcctgtgcgaaagaacaagaaccacatgggcattatgttggaactgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21364 JY8QFUQ01DNFZU productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21365 JY8QFUQ01AXVR3 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARAGASDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctcccgggaaggggctggtttgggtcgcacgtattagtgatgatgggagtagctccacctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaaaaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagcgggggcctctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21366 JY8QFUQ01C2JVO productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 932 92.2 201/218 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-16*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARHNYGNEKYIMDVW in-frame + gttttggatacaactttgccacctattggatcggctgggtgcgccacatgcccgggaaaggcctggaatggatggggatgatctttgctggtgactctgacaccagatacagtccgtccttccgaggccaggtcaccatgtcagccgacaagtccatcaacaccgcctacctgcagtggagcagcctgatggcctcggacaccgccatatattactgtgcgagacataattatggaaacgagaagtacattatggacgtctggggccaggggaccacggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21367 JY8QFUQ01BV67Z productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-25*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARHEGYNSRYYYFGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); gttctggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgGggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21368 JY8QFUQ01B9CT3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*02 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDRYPRSTAITAPDYW in-frame + cctctggattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcgcaactattatttatagtggcgatagtacatactacgcagactccgtgaggggccggttcaccatctccaaagacaattccaagaacacggtgtatctgcagctgaacaacctgagagccgaggacagggccgaatattactgtgcgaaagatcgctaccctcggtcgacagctattacagcgcctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21369 JY8QFUQ01AT8VL No results +21370 JY8QFUQ01BA09M unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 964 93.61 205/219 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 78 62.5 30/48 nt 8 8 X 8.8.X [2.17.38.11] CARGLAVILGGFGPY (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION gcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttggaccgtactggggccaggaacctgctcaccgtctcctcagcatccagccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21371 JY8QFUQ01DIWX1 productive Homsap IGHV3-33*05 F (see comment) 752 83.03 181/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21372 JY8QFUQ01B3VEO productive (see comment) Homsap IGHV3-72*01 F 971 92.86 208/224 nt 92.41 207/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); cctctggattcaccttaagtgatcactacatggactgggtccgccaggctccaAgggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21373 JY8QFUQ01BIGTS unproductive Homsap IGHV3-11*01 F 806 85.78 187/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 79 62.0 31/50 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDRRPWSFDAFDV## out-of-frame + cctctggattcaccttcagggactactatatgagttggattcgcctagcacctgggaaggggctggagtgggtttcatatattagtggtaatgtgtttaccaaacactacgcagactctgtgcagggccgattcaccatctccagggacaacgacaataagacagtctatctacagatggacaacctgagagccgcagacacggccatgtattactgtgcgagagacaggcgcccatggtcttttgatgcttttgatgtctggggccgggggcacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21374 JY8QFUQ01C85UX productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 932 92.2 201/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); cctctggatcaccctttggttattGatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21375 JY8QFUQ01A3PPQ unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 883 89.5 196/219 nt 89.04 195/219 nt 8 8 X 8.8.X [2.16.38.X] null - No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) gtgttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaaggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactgggggcgagggaaccctgattttccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21376 JY8QFUQ01CZVBC productive Homsap IGHV1-2*02 F 867 89.72 192/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [0.17.38.11] CARGFYGDHFDSW in-frame + tggatacatcttcaccggctactatttgcactgggtgcgacaggcccctggacaagggcttgagtggatgggatacatcgacccttacactggtgacacaaattatgcacagaggtttcagggcagggtctccatgaccagggacacgtccgtcagcacagtgtacgtggaggtgaggaggctgagatctgacgacacagctctttatttctgtgcgagaggcttttacggtgaccactttgactcctggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +21377 JY8QFUQ01CN8NE unproductive Homsap IGHV3-7*01 F 841 87.96 190/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - tctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +21378 JY8QFUQ01AT762 No results +21379 JY8QFUQ01A157B unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 473 68.35 149/218 nt 67.89 148/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found stop codons Low V-REGION identity (68,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcacctttcgcagctatgccatgagctgggtccgccaggctccaggaaGgggggctagagtgggtctcatctatcagtggtagtggtgataaaacaaagtacgcagactccgtgaagggccagggcacccaggtcaccgtctcctcagcatcccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +21380 JY8QFUQ01ABR1Q productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame - ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21381 JY8QFUQ01A3XGI No results +21382 JY8QFUQ01ACEIN productive Homsap IGHV3-9*01 F 981 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame - cctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccngagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21383 JY8QFUQ01CJTOK productive (see comment) Homsap IGHV4-59*03 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.38.11] CARGRTVVTVIDYMDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'AA' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift); tctctggtgactccattagcggttactattggacctggatccggcaaacccccaggaaAAgggactggagtggattggaaatatccactacagtgggagcaccaagtacagtccctccctcaagagtcgagtcaccacatcactcgccacgtccaagaatcaattcgccctgaagttgacctctgtgaccgctgcggacacggccgtctattattgtgcgagaggacgaacggtggtgactgttattgactacatggactactggggtcagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +21384 JY8QFUQ01CAL28 unknown (see comment) Homsap IGHV3-72*01 F 889 89.19 198/222 nt 88.29 196/222 nt 8 10 X 8.10.X [1.16.38.X] null + No rearrangement found in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcaccttaagtgacttctacatggactggctccgccaggctccagggaaggggctggagtggttggtcgcagtagaaacaaagctaatggttacagtacacaattcgccgcatctgtgatgggcagattcaccatctcaagagatgactcaaagaatttactatatctacAaaatgagcagcctgaaaaccgaggacacggccatttattactgtgctgtcgcagccccccccttatgacggctggggccagggaacccctggtcatcgctctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +21385 JY8QFUQ01B8393 No results +21386 JY8QFUQ01BOLT9 unproductive Homsap IGHV1-2*02 F 912 92.06 197/214 nt 90.65 194/214 nt Homsap IGHJ1*01 F 80 61.54 32/52 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [0.17.38.11] CARGPVSGWYTDYW# out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'AAGAG' (5 nucleotides at position 94 to 98 in the user submitted sequence), (cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacggGgcccctggacaagggcttgagtggatgggatggatcaaccccaaccctAAGAGtgtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactgggggccagggaacccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +21387 JY8QFUQ01A3L2A unknown (see comment) Homsap IGHV3-30*01 F 869 88.99 194/218 nt Homsap IGHJ1*01 F (see comment) 25 64.29 9/14 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagaggggactatgcttcgggggagtcgaccaaagcgagatacggtctggacgtctgggggccaagggaccacgggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21388 JY8QFUQ01CAIWR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1008 96.31 209/217 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDVW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +21389 JY8QFUQ01AXCSX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CARRSGRDGG#WFDSW out-of-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggattcacctttgtcgactatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtcgcagatattaatggaagaggtgctgccgcacactacgcagactccgtgacgggccgcttcaccctctccaaagacggttccaagaatacgatgtatctgcaaatgaacaccctgagagacgacgacacggccatatattactgtgcgagacgaagtgggcgtgatggggggctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21390 JY8QFUQ01AZLK8 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 86 of V-REGION: 'C' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift); tctctggcgactccatcagtggtcactactggagctggatcaggcagcCccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccaCgttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21391 JY8QFUQ01BQX6U unproductive Homsap IGHV4-61*02 F (see comment) 881 89.77 193/215 nt 88.37 190/215 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 8 7 X 8.7.X [1.17.38.11] XARQGDSSGPWNDY## out-of-frame + Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'TGGTTA' (6 nucleotides at position 23 to 28 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); tctccggtggctccatcagtacTGGTTAttactactggagctggatccggcagtccgccgggaagggactggaatggattggGgcgcatgtctgccagaggggacagcaactacaaccCcctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgngcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaact +21392 JY8QFUQ01AM6C9 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 221 97.83 45/46 nt 8 X X 8.X.X [1.5.X.X] null - No rearrangement found cctctggattcaccttcagtagctactggatgcactgggtccccca +21393 JY8QFUQ01AB1VC productive Homsap IGHV3-30-3*01 F, or Homsap IGHV3-30-3*02 F (see comment) 411 80.0 104/130 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 X 5 18 X.5.18 [X.X.38.11] CARDDFYSSGNYGGFGMDVW in-frame + Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtcactatgactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21394 JY8QFUQ01COJXK No results +21395 JY8QFUQ01BJRNU No results +21396 JY8QFUQ01AKA7I productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDYW in-frame + ctctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtccgcatggcctggtccagggcttcttcccc +21397 JY8QFUQ01APIK2 productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame + ctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21398 JY8QFUQ01B17PL No results +21399 JY8QFUQ01BH6X1 productive Homsap IGHV3-74*03 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcacactttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21400 JY8QFUQ01B20H0 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1053 98.62 214/217 nt 98.16 213/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD5-24*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CARSQGFWYFDLW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 176 to 176 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtcgcatccattagtagtagtagtggttacatatactacgcagactcagtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctgcaaAatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatcgcagggattctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21401 JY8QFUQ01BTQAH productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRDDDTSGHYSLFKYW in-frame + cgtctggattctcctttagtgcatatggcatacactgggtccgccagactccaggcaaggggctggagtgggtggctgttatgtattttgatggagttagaacattttatgcagactccgtgaagggccgattcaccctctccaaagactattccaagaacacggtgcatctgcaaatgaacagcctgcgagccgaggacacggctgtatattactgtgtgagagatgatgataccagtggtcactactctctgtttaaatattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21402 JY8QFUQ01A1QYN No results +21403 JY8QFUQ01CFJ5P productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD6-19*01 F 1 8 8 18 8.8.18 [1.17.38.11] CANHLCNRGECYSYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift); ctctggactcacctttaacaactctgccatgaGgctgggtccgacaggccccaggtaaggggctggagtgggtctcgactattagtggaacgggatataagacattcgacgcagactccgtgaagggccggttcaccatctccagagataattctaagaacacactatatctgcaaatgaagagcctgagacccgaggacacggccgtttattactgtgcgaaccatctgtgtaacagaggtgaatgctactcctattacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21404 JY8QFUQ01B5F9B unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F 809 86.51 186/215 nt 86.05 185/215 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CASLVTIK*QR*LHVG#FDVW out-of-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'TT' (2 nucleotides at position 49 to 50 in the user submitted sequence), (cause frameshift); tggatggtgggtccttcagtaataagtattggagttggattcgccagtTTcccagggaagggggctagagtggattggagaaatcaaccaaagtggaagcaccaactacaatccgtccctcatgagtcgagtcaccatctccatagacacgtccaagatgcagttctccctgaagttgacctctgtgaccgccgcggacacggctgtctattattgtgcgagtttagtgaccattaaatgacaacggtgactacacgtgggctttttgatgtctgggcccaagggacaatggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21405 JY8QFUQ01C4924 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*03 F 143 65.0 52/80 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 X X 8 X.X.8 [X.X.26.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctccggattcacttttagtgactattggatgagttggatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +21406 JY8QFUQ01CK0PG No results +21407 JY8QFUQ01CUQPV productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 7 8 15 7.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) ttctggattcagtcctaccgattttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtggacggtgtcgtggaactcagg +21408 JY8QFUQ01CMR93 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21409 JY8QFUQ01AXOPB unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt 93.15 204/219 nt 8 8 X 8.8.X [2.17.38.X] null + No rearrangement found in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggGggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactgggggccaggggaaccctggtcaccgtctccctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21410 JY8QFUQ01AJZPZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDQSPGVAVAGPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcaaagtccgggtgtagcagtggctggtcctgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21411 JY8QFUQ01AVQX9 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 487 68.95 151/219 nt 68.04 149/219 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [2.17.38.11] CAREDIVREGLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (68,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 76 of V-REGION: 'C' (1 nucleotides at position 135 to 135 in the user submitted sequence), (cause frameshift); tgtctggtggctccatcgccacttatcattggtggaacttgggtccgccagacccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtcCcctccagagtcgcgCttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +21412 JY8QFUQ01A2O1P unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactanttccccgaaccggtgacggtgtcgtggaactc +21413 JY8QFUQ01CLHAM productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +21414 JY8QFUQ01AI9XU No results +21415 JY8QFUQ01B51E2 unproductive (see comment) Homsap IGHV3-48*02 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARDVPGPK*QL#FDYW out-of-frame + stop codons cctctggattcagcttcagagactatggcatggcctgggtccgccaggctccagggaaggggctggagtgggtctcatacattggtaggattattagtgacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagggacgacgacacggctgtctatttctgtgcgagagatgtcccgggccccaaatgacaactacttttgactactggggccagggaaccctgcttaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggctccagggcttcttccccca +21416 JY8QFUQ01BH0GH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 849 87.0 194/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 3 8 8 10 8.8.10 [3.17.38.11] CASFRVLESGYW in-frame - tcaggtctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21417 JY8QFUQ01DBDMO No results +21418 JY8QFUQ01BW1XA productive (see comment) Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt 83.87 182/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.37.11] CVKDMVAGQGLLSRFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 77 of V-REGION: 1 nucleotides (from position 137 in the user submitted sequence), (cause frameshift) cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcacatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttcccccctggcgcccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21419 JY8QFUQ01B5QA5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 901 90.41 198/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDLYGADDLW in-frame + acctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccg +21420 JY8QFUQ01BXQL7 productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - tctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21421 JY8QFUQ01A4Y84 No results +21422 JY8QFUQ01AEV4J No results +21423 JY8QFUQ01BTAHR productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggGggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaactca +21424 JY8QFUQ01B8N31 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 896 90.37 197/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRSEYSS#NWFDPW out-of-frame + cctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +21425 JY8QFUQ01AN8DC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKEIAVSGEGALDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); ctctggattcacAgtttagcaactatgccatgagctgggtccgccaggctccagggaaggggccggagtgggtctcagctattactggtcttgatggtagaacattctacgcagactccgtgaagggccgtttctccatctccagagacaattccaagaacacgttgtatttgggaatgaacagcctgagagccgaggacacggccgtatattattgtgcgaaagagatagcagtgagtggtgagggggcgttggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21426 JY8QFUQ01CLC9U productive Homsap IGHV4-61*02 F 848 86.88 192/221 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD5-24*01 ORF 1 10 7 14 10.7.14 [1.17.38.11] CARGMATIKTVRFDPW in-frame + tctctggtggctccatgaggagtggaattaattcctggacatggatccggcagcccgccgggaagggactggagtggattgggcgtatctatatcaatggagacaccaactacaatccctccctcaagagtcgggccagcatatcaatggacacgtccaagaaccagttctccctgcacttgacctctgtgaccgccgcagattcggccgtctattattgcgcgagagggatggccacaataaaaacggtccgattcgacccctggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +21427 JY8QFUQ01B1YQJ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CILLYYDSRGVFSTDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggcgtgggtctcacgtattaaaagtgatggcagtggcacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagagcacgctgtttctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtatactgctttactatgatagtagaggtgtcttttcaaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21428 JY8QFUQ01DU512 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21429 JY8QFUQ01BWUNI No results +21430 JY8QFUQ01BWKUZ No results +21431 JY8QFUQ01CXTY7 unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 890 88.39 198/224 nt 87.95 197/224 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-14*01 ORF 3 8 10 X 8.10.X [1.17.38.11] CTADVPSPLAQK#DFW out-of-frame - stop codons in CDR2-IMGT at codon 59 of V-REGION: 'T' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); cctctggattcactttcaatggcgcctggatgaactgggtccgccaggctccagggaagggtctggagtgggttgcccgtataaaaaactTttggtgaaggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcaaaaaaaaggctgtatctgcagatggacagcctgagaatcgaggacacagccaagtattactgcaccgcagatgtcccgtcaccattagcgcaaaaatgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +21432 JY8QFUQ01DNFWY No results +21433 JY8QFUQ01BWMC8 No results +21434 JY8QFUQ01CPZTO No results +21435 JY8QFUQ01B8D69 No results +21436 JY8QFUQ01CYIE3 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1001 95.02 210/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 2 8 10 10 8.10.10 [0.17.38.11] CTTLPWEPLDYW in-frame - ctggattcactttcagtaatgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaactagaactgatggtgagacaacagactacgctgcacccgtcaaaggcagattcaccatctcaagagatgattcaaaaaacacattgtttcttcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtaccactcttccttgggagcctctcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21437 JY8QFUQ01BCXIK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 877 89.81 194/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); tccggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgGggtctcacggactaatgaagatgggagtatcacaaactacgcggactCccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21438 JY8QFUQ01BB0UE productive (see comment) Homsap IGHV3-33*04 F (see comment) 703 80.37 176/219 nt 79.91 175/219 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [2.17.38.11] CARDILDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); gcatttggattccctttcagcgactatggcatgcactgggtccgccCagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21439 JY8QFUQ01A9D9E productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ5*02 F 109 70.21 33/47 nt Homsap IGHD5-12*01 F 3 8 8 6 8.8.6 [1.17.38.11] CVSIGHGV in-frame + cctctggattcgcctttaggagtgagtggatgaactgggtccgccaagccccagggaaggggctggagtgggtcgcacacattgacactgatgggagtatcgcagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaatactttgtatctgcaaatggacagtctgagagccgacgacacggctatatattactgtgtaagcattggacacggagtgggcccgggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccg +21440 JY8QFUQ01AXEW2 productive Homsap IGHV3-11*03 F, or Homsap IGHV3-11*05 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*03 F or Homsap IGHV3-69-1*02 P or Homsap IGHV3-7*03 F or Homsap IGHV3-71*01 P 165 68.35 54/79 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 X X 19 X.X.19 [X.X.26.11] CATDGVGSTVKLMVMGPFDFR in-frame + ctctggattcgtctttaacaactatgccatgggctggatgaacagcctgagagccgaggacacggccgtttattactgtgcgacagatggagtagggtctactgtgaagttgatggttatgggcccttttgacttcaggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21441 JY8QFUQ01CERJX productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 854 88.84 191/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [0.17.38.11] CAREQLEYYYDNNGPKYW in-frame + ctggattcaccctcagggagtatattatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcaatgatctcacatgatggaagaagtcaagactatgtagactccgtgaagggccgattctccatctccagagacaactccaagaacacactgtatctgcaaatgaacagcctgagagttgaagacacggctgtatatttctgtgcgagagagcaactagaatattactacgataataatggtcctaaatactggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaaactca +21442 JY8QFUQ01CWNKI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.74 200/218 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CGKPIVGATGREMPVSLG in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctttagcaactatgccatgaactgggtccgccaggttccaggggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttccctgggggccaggggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21443 JY8QFUQ01AIAJ9 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 866 88.24 195/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARQLSGDYASFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtgcctccatcaccagtggtactttttactgggcctggatccgccagcccccagggaaggggctggagtgggttggcaatatctattctagtggtgtcgcctattacaacccgtccctcaagagtcgagtcaccatgtccgtcgacacgtccaagaatgagttttccctgacactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21444 JY8QFUQ01CEEGX productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21445 JY8QFUQ01BIVV0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacctttagcCacttttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21446 JY8QFUQ01CD286 unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 937 92.24 202/219 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [2.17.38.11] CARGMATAESW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccagggggacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +21447 JY8QFUQ01AFKB3 productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +21448 JY8QFUQ01AK2C9 No results +21449 JY8QFUQ01ATARJ unproductive Homsap IGHV3-48*02 F (see comment) 470 84.73 111/131 nt 83.97 110/131 nt Homsap IGHJ5*01 F 102 66.67 34/51 nt Homsap IGHD1-1*01 F 3 X 5 X X.5.X [X.X.38.11] CASGGKERLRSTTGLLSRHGRL# out-of-frame - Low V-REGION identity (84,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); ctctggactcaaccttcagcagctataactctgtgaAagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagtgggggaaaggaaagactacgaagtacgacgggactactatcacggcatggacgtctgggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccc +21450 JY8QFUQ01DJLQH unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CTKRLSGRPLVESGAP#FFDDW out-of-frame + stop codons ctctggattcacctttagcgactatggcatgagttgggtccgccaggctccagggaagggactggagtgggtctcaagtattatcgctaatggtggtgacacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagatgaacagccttagaggcgaggacacggccgtatattattgtacgaaaagactatccggacggccgcttgttgaatcaggtgcgccccttctttgacgactgggaccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21451 JY8QFUQ01DWRL7 No results +21452 JY8QFUQ01A0Q3Y unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 937 92.24 202/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD4-11*01 ORF 3 8 8 X 8.8.X [2.17.38.11] CAKQTIFDYYYYGLDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) gcctctggattcatgtttagtagctttcccatggcctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21453 JY8QFUQ01A1LFR No results +21454 JY8QFUQ01B259Y No results +21455 JY8QFUQ01BK210 No results +21456 JY8QFUQ01CO089 No results +21457 JY8QFUQ01DC9LM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 995 95.41 208/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +21458 JY8QFUQ01CBXLR productive Homsap IGHV3-48*01 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CATDRLRGDKYNFDDW in-frame - ctacggatttgtcttcagtggcactaatatgaattggctccgccaggctccagggaaggggctggagtggatttcacacattagtcacaatagtgaaaccatattctatgcagactctgtgaggggccgagtcaccatctccagagacaatgccaggaactcactgtatctgcacatgagcagcctgagagccgaggacacggcagtatattactgtgcgaccgaccgccttcgtggagataaatacaattttgacgactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21459 JY8QFUQ01ALDZZ No results +21460 JY8QFUQ01DHXHT productive Homsap IGHV4-39*02 F 920 90.95 201/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 3 10 7 14 10.7.14 [1.17.38.11] CARPGARETNNAWVDW in-frame + tctctggtggctccgtcagtaggagtgcctactactggggctggatccgccagcccccagggaaggggctggagtggattgggaccatctattatagtgggaccacatactccaatccgtccctcaagactcgagtcaccatgtccttggacacgtccaagaaccacatctccctgaagctgaattctgtgaccgccgcagacacggctgtttattactgtgcgagacctggggctagggagactaataacgcctgggtcgactggggccagggcaccctggtcaccgtctcctcggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcgccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtgcgtgaactca +21461 JY8QFUQ01DL7SV unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 842 87.61 191/218 nt 87.16 190/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKQKS*LW#YYFDQW out-of-frame + stop codons in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift); cctctggattcacgtttaaaacacatgccatgagctgggtccgccaggctccaggaaaAGggggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaaatcatagttatggatactactttgaccagtggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +21462 JY8QFUQ01CAAAT productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - gctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21463 JY8QFUQ01CMH9Z unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDQSCIVGPCGFDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); cttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtctcggctattagtggaagtggtgCgaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactgggggccagggagcccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactc +21464 JY8QFUQ01CUW2A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 831 87.85 188/214 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 15 8.8.15 [0.17.38.11] CAKVYTGAWGDPNFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggattcagctttagcaactttgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtacttttagcacccattatgccgactccgtgaagggccgcttcaccatctccagagacaatttcaggagcaccttatatctgcagatgaacaacctgagagccgacgacacggccatatattactgtgcgaaagtgtacaccggtgcctggggggatcctaattttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21465 JY8QFUQ01CI9HW productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt 87.21 191/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.17.38.11] CARDSASSGYARYDAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); gcctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggGggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21466 JY8QFUQ01B1X3U productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 18 8.8.18 [1.17.38.11] CSTGPSDLSRDYGDYGFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'CATGATGGAATG' (12 nucleotides at position 86 to 97 in the user submitted sequence), (do not cause frameshift); atctggattcaccttcagaaactatgccatgcattgggtccgccaggctccaggcaaggggctggagtgggtggcacttatatggCATGATGGAATGtttgatggaagaaatgaatattatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaatacggtgtatctgcaaatggacagcctgagagccgaggacacggctttgtattactgttcgacaggaccctcagaccttagtcgtgattacggtgactacggatttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +21467 JY8QFUQ01A6WYW unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 967 92.44 208/225 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt 8 7 X 8.7.X [5.17.38.11] CARGGPTFMI (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ccgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggccccacttttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21468 JY8QFUQ01BU1V2 No results +21469 JY8QFUQ01B42GA productive Homsap IGHV3-48*02 F 886 90.28 195/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [1.17.38.11] CARGQKWLQVLRWFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21470 JY8QFUQ01A8MB9 productive Homsap IGHV3-7*03 F 869 88.99 194/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame + cctctggattcacctttagcacctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21471 JY8QFUQ01DD9DB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 822 87.38 187/214 nt 86.92 186/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKESLVRGVISYYFDDW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) ctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcatctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggtttttcatctcaagagacaatttcaataatacattgtatctgcaaatgaatagcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctggttcggggagttatctcgtactactttgatgactggggccagggaaccctggtcaccgtctcctccgcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +21472 JY8QFUQ01BFAOT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKGIVGASMQADWFHPW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +21473 JY8QFUQ01C7525 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 157 to 157 in the user submitted sequence), (cause frameshift); tctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagGaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21474 JY8QFUQ01B3U1I productive (see comment) Homsap IGHV4-61*02 F 836 87.91 189/215 nt 86.05 185/215 nt Homsap IGHJ4*03 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARERSASMGAARELDSW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'GGTGCC' (6 nucleotides at position 24 to 29 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'CT' (2 nucleotides at position 42 to 43 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'TGGGG' (5 nucleotides at position 102 to 106 in the user submitted sequence), (cause frameshift); tctctggtggccccatcggcagtGGTGCCtactactgggacCTgggatccggcagGcccgccgggaagggattggagtggctcgggcgtgtttatagtggtTGGGGgggatcatcaattacagtccctccctcaagagtcgaatcaccatgtcgatagacacgtccaagaaccagttctccctgaagttgacctctgtgaccgccgcagacacggccttatattactgtgcgagagaacgtagtgcctcgatgggcgctgcgagagaacttgactcctggggccaggggaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21475 JY8QFUQ01AXFZP unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 848 87.33 193/221 nt 84.62 187/221 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 3 10 7 X 10.7.X [1.17.38.11] CARRHYGEGLFDY## out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 75 of V-REGION: 'G' (1 nucleotides at position 139 to 139 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 170 to 170 in the user submitted sequence), (cause frameshift); tctttggtggctccatcaccaataataattacttctggggctggatccgccagcccccagggGAagggggctggagtggattgggggAtgtccagtatagtgGggagcacctactccaGccccgtccctcaagaggcgGggtcaccatgtctgtggacgtgtccaaaaaGtcaggtctccctgagactgagctctgtgaccgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21476 JY8QFUQ01CR329 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 160 80.0 40/50 nt Homsap IGHD6-25*01 F 2 8 7 X 8.7.X [1.17.38.11] CARGTRYNNGLDA#FDVW out-of-frame + stop codons Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgctttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaact +21477 JY8QFUQ01CWYLE productive Homsap IGHV4-59*02 F (see comment) 741 83.18 178/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*02 F 2 8 7 11 8.7.11 [1.17.38.11] CARGDSRGLFDLW in-frame - Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctgggggccccgtgagaagtacttactggaattggattcgacaggccccagggaagggactggagtggattggctatgtctatttcagcgggagcagtctctacaacccctctctgagggggcgagttaacatctctgtggacacgtccaagaaccagttctccctgggtctgagttctgtgaccgctgcggacacggccgtgtatttctgtgcgaggggggattctcgtgggctctttgacctctggggccagggaaccctggtcaccgtctcttcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +21478 JY8QFUQ01CKA5O unproductive Homsap IGHV3-9*01 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD3-16*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDIGVHMWTIDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); ctctggattcacgtttgatgactatggcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggcattacttggaatagtggttacataggctatgcggactctgtgAaagggccgattcaccatctccagagacaacgccaagaactccctgtatctacagatgaacagtctcagagctgacgacacggccttgtattactgtgcaaaagatattggggtacacatgtggaccattgactactgggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +21479 JY8QFUQ01CYBYH productive (see comment) Homsap IGHV4-61*01 F (see comment) 753 82.73 182/220 nt 82.27 181/220 nt Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-22*01 F 1 10 7 13 10.7.13 [1.17.37.11] CARDGNERLLLFETW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaaccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggttgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatgagaggttattactctttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21480 JY8QFUQ01DB4C5 productive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 818 86.98 187/215 nt 85.58 184/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDYFDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'C' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'C' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); ctggatacaccttcaccgactacttcatacactggctgcgacaggccCcctggacaagCgacttgaCgtggatgggatggatcaaccctaagaatggtgacacaaagtatgcacagaactttcagggccgggtcaccatgaccagggacacgtccgtcagcaccatatatgtggaggtgagcagcctggaatctgacgacgcagccacttattactgtgcgagaggcttttatggtgactactttgactcctggggccagggagccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21481 JY8QFUQ01COI8H productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 1058 98.62 215/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD6-19*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDLAGQWLAFDYW in-frame + cctctggattcaccttcagtagctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatcttcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatttggcgggacagtggctggcatttgactactggggccagggaaccctgggtcaccgtctcctcagggagtgcatccgccccaaccct +21482 JY8QFUQ01ASNKJ unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 857 87.78 194/221 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-19*01 F 2 10 7 X 10.7.X [1.17.38.11] CAATMNYMSADSTGWYGGG#DYW out-of-frame - stop codons tctctggtggctccatcaataataggctctactactggggctggattcgtcagcccccagggaagggtctggagtggattgggagcatccataatagtgggagcacctactacagtccgtccctcgagagtcgtgtcatcatctccgtagacacgtccaacaagcggttcttcctgaggctgagctctgtgaccgccgcagacacagctatgtactactgtgcggcaacgatgaattacatgtccgccgatagcactggctggtacggcggggggtgactactggggccagggagcctcggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21483 JY8QFUQ01DR4DQ unproductive Homsap IGHV1-3*01 F 961 94.84 202/213 nt 93.9 200/213 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-24*01 ORF 1 8 7 X 8.7.X [0.17.38.11] CARWNNDLDY## out-of-frame - in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) tggatacaccttcagtacctatactatgaattgggtgcgccagGgcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattgggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +21484 JY8QFUQ01AYFQ1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt 89.4 194/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift); ctctggatacagttttaacagttatgccatgacttggGgtccgccaggctccagggaaAGggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21485 JY8QFUQ01AV1JS productive (see comment) Homsap IGHV3-7*02 F 942 92.27 203/220 nt 90.91 200/220 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'CT' (2 nucleotides at position 66 to 67 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'GA' (2 nucleotides at position 99 to 100 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 133 to 133 in the user submitted sequence), (cause frameshift); agcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccaggggaagggcCTgggagtgggtggccaacataaaggaagacggGAagttgagagatattatgtggactctgtgaaggGgccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21486 JY8QFUQ01AVLE1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame + ctctggattctccgtcagtaattactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc +21487 JY8QFUQ01BF5XC unproductive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagGggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21488 JY8QFUQ01A3ZP4 unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1055 97.74 216/221 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 124 72.0 36/50 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [2.17.38.11] CARPYCGGDCHNRGAFDI## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cagcgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctgggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +21489 JY8QFUQ01A8GSF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt 85.65 185/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.17.37.11] CVKDISRSGCFEYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 67 of V-REGION: 'A' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 98 of V-REGION: 1 nucleotides (from position 197 in the user submitted sequence), (cause frameshift) ctctggattccagtttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaAccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgagacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +21490 JY8QFUQ01DDCKT productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [2.17.38.11] CAKDLFQVSTTYFDYW in-frame + gcctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc +21491 JY8QFUQ01BMWQU No results +21492 JY8QFUQ01B3LSL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21493 JY8QFUQ01C0PGJ productive (see comment) Homsap IGHV4-39*02 F 942 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [1.16.38.11] CARRYSWNYERFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtactaataattactactgggcctggatccgccagccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaaggggccccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcaggc +21494 JY8QFUQ01CB7X9 productive Homsap IGHV3-11*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame - Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21495 JY8QFUQ01ACX19 No results +21496 JY8QFUQ01BE1KI productive Homsap IGHV3-48*01 F 851 88.07 192/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + tctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtaccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21497 JY8QFUQ01BOCJK No results +21498 JY8QFUQ01DK9PC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 852 87.73 193/220 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD2-8*01 F 1 8 8 19 8.8.19 [2.17.38.11] CAKVFQVSGEHHFYYYGMNAW in-frame - agcctctggattcatctttagtaattatgccatgagttgggtccgccaggccccagggagggggctggagtgggtctcaactatcagtgccaatggagacaacacatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacagtgtatatgcaaatgaacagcctgaaagccgaggagacggccgtctatcattgtgcgaaagtcttccaggtgtctggcgaacatcacttctactactatggtatgaatgcctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21499 JY8QFUQ01A5JOZ productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame - ctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21500 JY8QFUQ01BWXYO No results +21501 JY8QFUQ01AP035 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CANELGYCSGG# out-of-frame + cctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgccctggtccagggcttcttccccc +21502 JY8QFUQ01A8WHD unproductive (see comment) Homsap IGHV3-7*01 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARVGLWLPRNILL*LL# out-of-frame + stop codons in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift); cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaaatTgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtggggctatggttaccgaggaatatacttctttgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +21503 JY8QFUQ01CBAN4 productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21504 JY8QFUQ01A23AX productive Homsap IGHV3-11*04 F 1053 98.62 214/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 17 8.8.17 [1.17.38.11] CANNLPPGIEMATIPYDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtggtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgaataacctccccccaggaatagagatggctacaattccgtatgactcctggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaaccc +21505 JY8QFUQ01DUD1Z No results +21506 JY8QFUQ01B6OPE unproductive Homsap IGHV3-7*01 F 960 93.18 205/220 nt 92.27 203/220 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CVSSPYFYDSNGY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); agcctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagGggggctggagtggtggccaagcataaAagcaagatgcaagtgaggaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +21507 JY8QFUQ01APCSR unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDNYGDYW# out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21508 JY8QFUQ01CQSMJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +21509 JY8QFUQ01BXQU2 No results +21510 JY8QFUQ01DN20F unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 781 83.78 186/222 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-18*01 F 3 8 10 X 8.10.X [1.17.38.11] CTWGQHWLFSAY#W out-of-frame - Low V-REGION identity (83,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggactcactttcagtgacgcctggatgacctgggtccgccaggttccagggaagggctggagtggggttgcccatattagatggaactctgatgactggaccacagactacgctactcccgtgaagggcagattcaccatctcaaaagatatttcagagaacacgctgtatctacaaatgaacagcctgataagcgaggatacaggcgtttattactgtacctggggacagcactggttattttcggcttacctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +21511 JY8QFUQ01DGMBL productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-3*01 F 1 8 8 20 8.8.20 [0.17.38.11] CARDHRSGALEWSHHYHGMDVW in-frame + tggttacatcttcacccactatggtatcaactgggtgcgccaggcccctggacaagggcttgagtggatgggatggatcagcgcctacagtggtaacacaaagtatgcacagaaggtccagggcagagtcaccatgaccacagacacttccacgagtacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagatcacagaagcggggctttggagtggtctcaccactaccacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +21512 JY8QFUQ01CUHW8 unknown (see comment) Homsap IGHV4-4*07 F 818 86.98 187/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccaggggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +21513 JY8QFUQ01B68NJ productive (see comment) Homsap IGHV3-9*01 F 887 89.91 196/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'G' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); cctctggatttaactttgatcaatatgccatgtattgggtccgGgcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggcGtatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaaggggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21514 JY8QFUQ01BT47B unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +21515 JY8QFUQ01CF1B0 unproductive Homsap IGHV4-61*02 F 830 86.43 191/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARDTGQTYGRGP#LDYW out-of-frame - tctctggtgcctccataaataggggtaattattactggaactggatccggcagcccgccgggaagggcctggaatggattggccgaatctatacaagtgggagcaccatctacaacccctccctcgggggtcgagtcaccatgactgtagacccgtccgagaatcagttcttcctgagactgagttctgtgaccgccgcagacacggccgtttatttttgtgcgagagacactggacaaacctacggtcgggggccctttggactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgtctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21516 JY8QFUQ01B2QKI No results +21517 JY8QFUQ01BRXD7 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-7*02 F 105 58.33 49/84 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +21518 JY8QFUQ01CP17D productive Homsap IGHV3-9*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + cctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21519 JY8QFUQ01CUYJY No results +21520 JY8QFUQ01C2M9W productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctactggatgcattGgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21521 JY8QFUQ01CL3ZB No results +21522 JY8QFUQ01DNTEO No results +21523 JY8QFUQ01DFQND unproductive Homsap IGHV4-39*02 F 829 86.76 190/219 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD5-12*01 F 1 10 7 X 10.7.X [1.17.38.11] CARHVVLDNRYSVWPRILDS## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctgggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +21524 JY8QFUQ01A8LB5 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 924 90.91 200/220 nt 90.0 198/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [2.17.38.11] CNTDLGGSWYTFYSDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'T' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 5 nucleotides (from position 90 in the user submitted sequence), (cause frameshift) gtctctggatacactgtcaTgaaatgcctggatgagttgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaaggtgatggtgtgacaacagaatacgctgcatccgtgaaaggcagattcaccatcacaagagatgactcaaggaacacgttgtatctacaaatgaacagcctgaaaaccgaggacacagccatatattattgcaacacagatctgggcgggagttggtacaccttctattctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21525 JY8QFUQ01BFYP6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1045 97.72 214/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [2.17.38.11] CARDLTGYSSERNYW in-frame - gcctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21526 JY8QFUQ01AU1DC unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYFGTL#DYW out-of-frame + stop codons cctctggattcacctttaccaactatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttggaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +21527 JY8QFUQ01BLX8G productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1011 97.2 208/214 nt 96.26 206/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagctactaTtttgcactgggtgcgacaggCcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcgaggggacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21528 JY8QFUQ01BVDBD unproductive Homsap IGHV3-13*01 F 961 94.84 202/213 nt 94.37 201/213 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD1-1*01 F 2 8 7 X 8.7.X [1.16.38.11] CARGSSKAYNWFD#PG out-of-frame - in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctgagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgaccccctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +21529 JY8QFUQ01A3552 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 829 86.76 190/219 nt 86.3 189/219 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD5-18*01 F 2 8 8 16 8.8.16 [2.17.38.11] CVKDWGPNRQMWFGESLW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'GCTGTTGCC' (9 nucleotides at position 94 to 102 in the user submitted sequence), (do not cause frameshift); gcctctggattcacgttcagcagctatgccatgacctgggtccgccagactccagggaaggggctggagtgggtctcaactattcatggcggtGCTGTTGCCggtggcaccacagactacgcggtctccgcccagggtcgattcaccatctccagagacaattccaagagcacactgtatttgcaaatgagcgacctgagacccgaggacacggccctctatttctgtgtgaaagactggggccccaatcggcagatgtggttcggggagagtctctggggccagggaactctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +21530 JY8QFUQ01AIGWB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 3 8 8 17 8.8.17 [1.17.38.11] CAKKNIIIRGLIYNNFDYW in-frame + cctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaaacattataattcggggacttatttataacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21531 JY8QFUQ01BY21V productive Homsap IGHV3-7*01 F 868 89.35 193/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + tctgggctcagcgtcagtaactaccgcatgggctgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21532 JY8QFUQ01C4VB4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - agcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +21533 JY8QFUQ01BZBYM productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 8 8 20 8.8.20 [1.17.38.11] CTRTQFDPDYGDYETGYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); cggctggattcaacttccgatcttatgccatgtactgggtccgccaggCccccaggcaaggggctggactgggtggcagttatttggcatgatggcagtaatcaatactatgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacattgtttctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtacgaggacgcaatttgaccctgactacggtgactacgagacggggtacggtatggacgtctggggccaagggacaacggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +21534 JY8QFUQ01B1CD9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21535 JY8QFUQ01DE4ZI unproductive (see comment) Homsap IGHV4-39*02 F 849 87.0 194/223 nt 86.1 192/223 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD5-12*01 F 1 10 7 X 10.7.X [2.17.38.11] CARHVVFGQ*IQCLASYP*FL# out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 27 of V-REGION: 'C' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 177 to 177 in the user submitted sequence), (cause frameshift); tgtctctCggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccCctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggtttttggacaatagatacagtgtctggcctcgtatccttgattcctgggggccagggaacccttgtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21536 JY8QFUQ01CQO22 No results +21537 JY8QFUQ01B924O unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 974 93.67 207/221 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSQSRYSWGDFLH## out-of-frame + tctctggtgactccatcagcagtactagttactactggggctggatccgccagcccccagggagggggctggagtggattggaagcatctattatagtgggagcacctcctacaacccgtccctcgagagtcgaatcaccatgtccgtagacatgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtttatttctgtgcgcggtcccagagtagatacagttggggtgacttcttacactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgnagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +21538 JY8QFUQ01CSWYE productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 994 95.83 207/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.16.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'G' (1 nucleotides at position 210 to 210 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtagctattggatgaactgggtccgccaggctccagggcagggctggagtgggtggccactataaagcaagatggaagtgagaaatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtaGttactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21539 JY8QFUQ01ASX0M productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21540 JY8QFUQ01C9X2Z unproductive (see comment) Homsap IGHV4-61*02 F 883 89.09 196/220 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 10 7 X 10.7.X [1.17.38.11] CARDPQGYL*WW*LPLFCNGRL# out-of-frame - stop codons ctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaacccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaaccngttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagacccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctgggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgcccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21541 JY8QFUQ01CH9K4 productive Homsap IGHV2-5*02 F, or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F 913 86.42 210/243 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 3 10 7 11 10.7.11 [9.17.38.11] CAHFGPQEHFDFW in-frame - accctcaccctgacctgcgacttctctggattctcactcagcaccaatgtaatgggtgtgggttggatccgccagcccccgggagaggccccagactggctcgctctcatttattgggatgatgataagcgataccggccatccctagagagtagactcaccatcaccaaggacatctccacaaaccaggtggtccttagaatgaccgacatgggccctgcagacacagccacatatttctgtgcacactttggaccacaggagcacttcgacttttggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21542 JY8QFUQ01C7ZJ7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 887 89.91 196/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVAVGMSGWFDPW in-frame + tctctggatttacctttagcagttatgccatgaactgggtccgccaggctccagggaaggggctggtgtgggtctcacgtattaatggtgatggcagtagcacaagctacggggactccgtgaagggccgattcaccgtctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgcgagtcgacgacacggctctatattattgtgcaagaggccgtatagtagcagttgggatgtcaggctggttcgacccttggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagccctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21543 JY8QFUQ01A47M7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21544 JY8QFUQ01DK51Z No results +21545 JY8QFUQ01BBRVM unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 940 92.63 201/217 nt 90.78 197/217 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-3*01 F 2 8 7 X 8.7.X [2.16.38.11] CARGGLEPVDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 44 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) gccctctggattcaccttGcantacatactggatgcactgggtcgccaagctccaggaaggggctggtgtgggtctcccgtatcaatcctgatggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21546 JY8QFUQ01AWVGJ unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CTRDIGGRYSY## out-of-frame + in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); gcctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtGgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21547 JY8QFUQ01BL43C productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +21548 JY8QFUQ01BDBP6 unproductive (see comment) Homsap IGHV3-7*01 F 981 94.93 206/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDPL*WWWL#GAFDIW out-of-frame + stop codons ctctggattcacctttagtaataattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacatcaagcaagatggaagtgagaaagtctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgcaaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagaccccctataatggtggtggttatggtgcttttgatatctggggccaagggacaatggtcaccgtctctttagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21549 JY8QFUQ01BTB0T productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21550 JY8QFUQ01ASTD9 productive (see comment) Homsap IGHV1-18*01 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 8 8 8 8.8.8 [0.17.38.11] CARDRPNEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'GC' (2 nucleotides at position 46 to 47 in the user submitted sequence), (cause frameshift); tggttaccccctttaatacctatggtatcacctgggtgcgacaggGCcccctggacacggccttgagtggatggggtggatcagcgttcacgatggcaacacaaactatgcacagagtctccagggcagagtcaccctgaccacagacacatctacgagcacagcctacatggaactgaggggtctcagatctgacgacacggccgtttattattgtgcgagagatcgcccgaatgaattctggggccagggaaccctggtcaccgtcttctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +21551 JY8QFUQ01BWTX8 unproductive (see comment) Homsap IGHV3-48*02 F 986 94.95 207/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [1.17.38.11] CARPAGAG*PFFA#YYSGLDVW out-of-frame + stop codons cctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggcagggtgacccttttttgccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21552 JY8QFUQ01BJZUF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 869 88.99 194/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARVRGYYGGQYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21553 JY8QFUQ01AEL2L unproductive (see comment) Homsap IGHV4-30-2*02 F, or Homsap IGHV4-55*06 P or Homsap IGHV4-59*01 F or Homsap IGHV4-59*02 F or Homsap IGHV4-59*03 F or Homsap IGHV4-59*07 F or Homsap IGHV4-59*09 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*03 F or Homsap IGHV4-61*07 F or Homsap IGHV4-61*08 F 189 91.3 42/46 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 2 X X X X.X.X [X.X.15.11] CARGGSVGATGI*SRD## out-of-frame - stop codons gatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtcggtgggagctactggaatctgatcccgggactgggggccagggaaccctggtcaccgtctactccagcatcccccgaccagcccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +21554 JY8QFUQ01BEG02 unproductive (see comment) Homsap IGHV3-48*02 F 874 89.04 195/219 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [2.17.38.11] CARAGGWEI##YFDYW out-of-frame + stop codons acctctggattcatcttcagtcagtataaaatgaattgggtccgccaggctccagggaaggggctggagtgggtttcagaaattagttttagaagcagaaccgtacactacgcagactctgtgaggggccgcttcaccgtctccagagacaatgccaagaactcactgtatctacaattgaacagcctgagagacgaggacacggctatatattactgtgcgagagcggggggctgggagattcgactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21555 JY8QFUQ01CC6FI productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21556 JY8QFUQ01BZ6X5 No results +21557 JY8QFUQ01CKAZJ productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F or Homsap IGHV3-69-1*01 P 814 86.57 187/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 7 12 8.7.12 [2.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggaatgggtctcaattatttatatcagtggtagcacatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt +21558 JY8QFUQ01BPEGS productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +21559 JY8QFUQ01CN2FZ productive (see comment) Homsap IGHV3-48*01 F 1080 99.54 216/217 nt 99.08 215/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASIFGVVPLGNYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagGaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21560 JY8QFUQ01DGF6D productive (see comment) Homsap IGHV1-8*01 F 960 95.26 201/211 nt 94.79 200/211 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 7 8 11 7.8.11 [X.16.38.11] CARGDSSAYPDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift) gatacaccttcatcaattatgatatccactgggtgcgacaggccactggacaagggcttgagtggatggacggatgaacccgaacagtggtaacacaggctatgcaccgaagttccagggcagagtcaccatgaccagggacacctccataagcacagcctacatagagttgaccagcctgagatctgaggacacggccgtgtattactgtgcgagaggggacagtagcgcttaccccgactattggggccagggaaccctggtcaccgtctcctcaccatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +21561 JY8QFUQ01CMHIL productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-25*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARHEGYNSRYYYFGYW in-frame + gttctggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21562 JY8QFUQ01A7LQC productive Homsap IGHV4-59*02 F 962 94.42 203/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 3 8 7 17 8.7.17 [1.17.38.11] CARHSMGVTIVRGHWFDPW in-frame + tctctggtggctccgtcagcagttattactggagctggatccgacagcccccagggaagggactggagtggattggctatatccatgacagtgggagcagcaactacaacccctccctcaagagtcgagtcaccatatctgtggacacgtccaagaaccagttctccctgaagctgacttctgtgaccgctgcggacacggccgtatattactgtgcgagacattctatgggtgttactatagttcggggacactggttcgacccctggggccagggaaccctggtcaccgtctcatcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaacctc +21563 JY8QFUQ01B3HUT productive Homsap IGHV4-39*02 F 947 91.86 203/221 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [1.17.38.11] CARRYSWNYERFDPW in-frame + tctctggtgactccatcagtactaataattactactgggcctggatccgccagcccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcgtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21564 JY8QFUQ01APBO9 No results +21565 JY8QFUQ01DFUY0 unproductive (see comment) Homsap IGHV5-51*04 F 869 88.99 194/218 nt 87.16 190/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CACYFDSKWF#FDYW out-of-frame + stop codons in FR2-IMGT at codon 48 of V-REGION: 'TA' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 71 of V-REGION: 'TC' (2 nucleotides at position 125 to 126 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'T' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); gttctggatacgtctttccctcctactggatcgcctgggtgcgccagatgccccggTAaaaggcctggagtggctgggaaccatctatcCccggcgactctgacaccacatacagcccgtcattTCccaaggccaggtcaccatgtcagtcgacacgTcccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacagcgccatttactattgtgcgtgttattttgatagtaagtggtttctttgactactggggccagggaacccaggtcaccgtctcctccagcctccaccaagggccatcggtcttgccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21566 JY8QFUQ01AI0WO No results +21567 JY8QFUQ01DGWWO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKENYFESSGYHGMNVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcacctttaccaactatgccatgacctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtaatcgtggtactggagtgtactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagagccgaggacacggccctttattactgtgcgaaagagaattactttgagagtagtggttatcacggtatgaacgtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagataggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21568 JY8QFUQ01BDY1S No results +21569 JY8QFUQ01B2PSJ unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21570 JY8QFUQ01CUSAF unproductive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 786 85.51 183/214 nt 84.58 181/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDYFDSW in-frame + stop codons in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'GC' (2 nucleotides at position 46 to 47 in the user submitted sequence), (cause frameshift); tggatacaccttcaccggActacttcatacactggctgcgcaaggGCcccctggataacgacttgagtggatgggatggatcaaccctaagaatggtgacacaaagtatgcacagaactttcagggccgggtcaccatgaccagggacacgtccgtcagcaccatatatgtggaggtgagcagcctggaatctgacgacgcagccacttattactgtgcgagaggcttttatggtgactactttgactcctggggccagggagccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +21571 JY8QFUQ01APX1Q No results +21572 JY8QFUQ01AFCMU unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYD*GEYAMDVW in-frame + stop codons gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactagggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21573 JY8QFUQ01A3GYC unproductive Homsap IGHV1-2*02 F 826 87.79 187/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [0.16.38.11] CARDGISMTLVRGVRPFDY## out-of-frame - in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) tggatacaccttcatcggccattatatacattgggtgcgacaggccctggacaagggcttgaatgggtggggtggatcaaccctaacagtggtgttacaaactatgcacagcagtttcaggacagggtcaccatgaccgtcgacacgtccatcagcactgcctacatggacctcaaaagtctaaagtctgacgacacggccatctattactgtgcgagagacggaataagtatgactctggttcggggagttaggcccttcgactactgggggccagggaaccctggtcagcgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21574 JY8QFUQ01DH0U6 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 962 92.41 207/224 nt 91.52 205/224 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.38.11] CTHLREEMSYEW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); cctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggGggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaAaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +21575 JY8QFUQ01ABZJI unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDAKSGDA#EAFDIW out-of-frame + stop codons in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggGAagggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatgcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21576 JY8QFUQ01CC7HQ productive (see comment) Homsap IGHV4-61*02 F 878 89.04 195/219 nt 88.13 193/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.16.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctccggtggctccatcagtactggttattactactggGagctggatccggcagtccnccgggaagggactgaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21577 JY8QFUQ01C8FZV unproductive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 887 89.91 196/218 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD3-10*01 F 3 9 7 X 9.7.X [1.17.38.11] CAAQIWGHGELFSKYW# out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tctctggtgactccgtcagcagtgataactggtggagttgggtccgccagaccccagggaaggggctggagtggattggagaaatctatcatggtgggaccaccaactacaatccgtccctcaagggtcgagtcaccttatcggtcgacaagtccaagaaccaattctctctgagaatgacctcttttaccgccgcagacacggccgtgtattactgtgcggcccaaatctggggtcatggggagttattttccaaatattgggggcccgggaatcctgggtcaacgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagccctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21578 JY8QFUQ01A4T7B unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +21579 JY8QFUQ01AAX25 productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 1049 98.17 214/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-13*01 F 3 8 8 12 8.8.12 [1.17.38.11] CVKVGQLGDGMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaccttcagtagctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcatttatacggtatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacactctgtatcttcaaatgagcagtctgagagctgaggacacggctgtgtattactgtgtgaaagtgggtcagctgggggacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagggagtgcatccgccccaaccct +21580 JY8QFUQ01CPCJB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 987 94.55 208/220 nt 94.09 207/220 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'T' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); ggcctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatTgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +21581 JY8QFUQ01B2X5Y productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +21582 JY8QFUQ01AOB3M unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [2.17.38.11] CANELGYCSGG## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +21583 JY8QFUQ01BV15J productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 1 9 7 16 9.7.16 [1.17.38.11] CARDQRGRFGTSSTFDYW in-frame + tctctggtgactccatcagcaatgatagttggtggagttgggtccgccagcccccagggaaggggctggagtggattggggaaatctatcatactgggagcaccaactacaacccgtccctcaagagtcgagtcaccatatcactcgacaagtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacgcggccgtctattactgtgcgagagatcagcggggccgatttggcacctcgtcaacctttgactactggggccagggagcccaggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggcaacgtggtcgtcgcatgcctggtccagggcttcttccccc +21584 JY8QFUQ01AK0SS productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*06 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [0.17.38.11] CARGDGYNFGGLDYW in-frame - tggattcaacttcataggttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactccgtgaggggccgatccatcatttccagagacgattctaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21585 JY8QFUQ01C3XGP productive (see comment) Homsap IGHV2-5*02 F (see comment) 882 84.84 207/244 nt 84.43 206/244 nt Homsap IGHJ4*01 F 195 89.58 43/48 nt Homsap IGHD1-1*01 F 2 10 7 11 10.7.11 [9.17.38.11] CARIGRLEHFDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); gactctcacgctgacctgtaccgtctctggcttctcgctctccactcctggcgtgggcgtggcctggctccgtcagTcccccaggagaggccctggagtggcttgcactcatttactgggatgatgatagccgctatagcccatctctgaaggacagactcaccatcaccaaggacacctccgaaaaccttgtggtcctgacactcagcgacatcgatacagtggacatcgccacatatttttgtgcacgcataggccgtctggaacactttgactcctggggccaaggaatactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +21586 JY8QFUQ01CZE4X productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21587 JY8QFUQ01A841E unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21588 JY8QFUQ01B5WL6 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD2-21*02 F 3 8 8 20 8.8.20 [1.17.38.11] CARLPYIVVLTNIISPTYFDFW in-frame + ttctggatacagttttaccagttactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctgctgactctgataccagatacagcccgtccttccaaggccaggtcagcatctcagccgacaagtccatcgacaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgcggctgccatatattgtggtgctgactaatataatctccccaacctactttgacttctggggccagggaaccccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21589 JY8QFUQ01AN5AH productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1073 98.64 218/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARDRGPSSSSKMEYDYW in-frame + tctctggtggctccatcaacagtggtggttactactggagttggatccgccagcacccagggaagggcctggagtggattgggtacatctattacagtgggagtacctactacaacccgtccctcaagagtcgagttaccatatcagtagacacgtctaagaaccagttctccctgaagctgagctctgtgactgccgcggacacggccgtgtattactgtgcgagagatcggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21590 JY8QFUQ01CTCEY productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 885 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARELGGSGTCGFDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); tggatacacCcttcaccaggcactatatgcactgggtgcgacaggCcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggggcagagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccc +21591 JY8QFUQ01BD4OW unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 777 83.41 186/223 nt 82.51 184/223 nt 8 10 X 8.10.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 83 of V-REGION: 'G' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 180 to 180 in the user submitted sequence), (cause frameshift); ctctgggttcgttttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcGaaaaaacatggtgtatctgAcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgtagggactcggggtccaccgtctcctcagcatccccgaccagccccaaggtccttcccgctgagcctctgccagcacccagccagatgggaacgtggctcatcgcctgcctggtccaggggcttcttccccccaggagcc +21592 JY8QFUQ01CZCQ1 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); gcctctggatcacctttggttattgatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21593 JY8QFUQ01C1VSK productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 767 83.26 184/221 nt 82.35 182/221 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD3-3*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARRWSGTYPFASW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'T' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); tctctggtggctcactcagaagtagtagtcaccattggggctggattcgtcagTccccccgggaaggggctggagtggcttgggactgtcgactttcgtgggaccacccactacaacccgtccctcatgggtcgactcacgatatccgtcgacgcgcccaagagtcaaatgtccctgcacttgagctctgtgaccgccgcagacacggctTttttacttctgtgcgagacgctggagtgggacttatccgtttgcctcctggggccagggcatcccggtcatcgtctccccagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +21594 JY8QFUQ01CJEC0 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 876 94.36 184/195 nt 8 8 X 8.8.X [1.17.30.X] null + No rearrangement found cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccg +21595 JY8QFUQ01DGMMR No results +21596 JY8QFUQ01B53Q6 productive Homsap IGHV1-3*01 F 966 94.86 203/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARWNNDLDYW in-frame + tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21597 JY8QFUQ01BKCCN unproductive Homsap IGHV3-48*01 F 873 89.4 194/217 nt 86.64 188/217 nt Homsap IGHJ4*03 F (see comment) 132 75.0 36/48 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [1.17.38.11] CARASTFYYDGSGYRDVFDI## out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 43 of V-REGION: 'T' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 91 in the user submitted sequence), (cause frameshift) tctctggcttcagtttgagtacctTataccatgGaactgggtccgTccaggctccagggaaggggctggagtgggtttcactcattagtaagatagtaatgtcatatactacgcGggactctgtgaAagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatgggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcacccctcctccaagagcacctctggggggcacagcggccctggggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaactcag +21598 JY8QFUQ01CSJ0C productive Homsap IGHV3-7*03 F 842 87.61 191/218 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctccggattcacttttagtgactattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21599 JY8QFUQ01CW0P2 unproductive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRDGGVIVVVPMDYYGMDV## out-of-frame + ctctggtttcacatttagtacgtactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcgagatggaactgagagtcattatgtggactctgtgaagggccgattcatcatctccagagacaactccaggaatttactgtatctccaaatgaacagcctgagagtcgaagacacggctgtgtattattgtgtgagagatgggggtgttattgtagtagtgccaatggactattacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21600 JY8QFUQ01ARQ2P productive (see comment) Homsap IGHV3-7*01 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.16.38.11] CAISSDFYSTGHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) ctctggattcaacttcagaacctattggatgggctggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21601 JY8QFUQ01AIBXR No results +21602 JY8QFUQ01BCNOO unknown (see comment) Homsap IGHV3-48*03 F 883 89.5 196/219 nt 89.04 195/219 nt 8 8 X 8.8.X [2.17.38.X] null + No rearrangement found in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggAttttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21603 JY8QFUQ01CD118 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [1.17.38.11] CVKDRDFLWGTYRLQLEHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcagatttagcagctatgccatgagctGgggtccgccagactccagaaaaggggcttgaatgggtctcaggcatcaatgataacggtcgaagcataaactacgcgggctccgtgaagggccggttcaccatctccagagacaattccaagagcacgttgtatctgcagatggatagcctgagccccgaggactcgggcatatattattgtgtgaaagatcgtgatttcctttggggcacttatcgtcttcaacttgaacattggggccagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc +21604 JY8QFUQ01AJ5UO unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaacctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +21605 JY8QFUQ01BXKPL productive (see comment) Homsap IGHV3-74*03 F 837 87.56 190/217 nt 86.18 187/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcacgtttCcacacctcctggatgcactgggtccgccaaggtccaggGgagggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaAagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21606 JY8QFUQ01CKWEZ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 65 of V-REGION: 2 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggagggggctggagtgggtctctggtattaatcggaatggtgatagcaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21607 JY8QFUQ01CMIT0 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 937 91.78 201/219 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKKYHYGSGTYLYYFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactgggggccagggaaccctggtcaccgtctcctcagcattcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21608 JY8QFUQ01CJVQ5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 952 92.34 205/222 nt 91.89 204/222 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD4-11*01 ORF 3 8 8 16 8.8.16 [3.17.38.11] CAKQTNFSTTTTTVWTSG in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); gcagcctctggaAttcatgtttagtagctttcccatggcctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgaatttttcgactactactactacggtttggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +21609 JY8QFUQ01AJLXW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-21*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - ctctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtttattactgtgcgagaggccgaatagtgtcggttggtatgtcaggctggttcgacccctggggccagggaaccctggtctccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21610 JY8QFUQ01DPD05 No results +21611 JY8QFUQ01DAAJK productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARGPKYYYDSSGFEDLW in-frame - ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaggtcccaagtattactatgatagcagtggtttcgaagacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21612 JY8QFUQ01AWYBC productive (see comment) Homsap IGHV3-7*01 F 903 91.16 196/215 nt 90.23 194/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 8 14 7.8.14 [1.16.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 2 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 76 in the user submitted sequence), (cause frameshift) cctctggattacttttacaactattggatgacctgggttcgccaggntccagggaaggggctggaatgggtggccacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21613 JY8QFUQ01APB9W No results +21614 JY8QFUQ01CKBE4 No results +21615 JY8QFUQ01CCNXT productive Homsap IGHV3-7*01 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [0.17.38.11] CARGSYWHYDTFGDYW in-frame - ctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21616 JY8QFUQ01BX80Q productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21617 JY8QFUQ01DLL7L productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 799 85.98 184/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame - ntctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21618 JY8QFUQ01AVLQ7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 1 8 8 19 8.8.19 [1.17.38.11] CTKDYPDGRLLNQVRPFFDDW in-frame - cctctggattcacctttagcgactatggcatgagttgggtccgccaggctccagggaagggactggagtgggtctcaagtattatcgctaatggtggtgacacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagatgaacagccttagaggcgaggacacggccgtatattattgtacgaaagactatccggacggccgcttgttgaatcaggtgcgccccttctttgacgactgggaccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21619 JY8QFUQ01BW8TM unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 229 57.36 113/197 nt 8 8 X 8.8.X [1.17.31.X] null - No rearrangement found Low V-REGION identity (57,36% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21620 JY8QFUQ01CQPW7 No results +21621 JY8QFUQ01CCIFC unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcacctttatcaactatggcatgagctGgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21622 JY8QFUQ01B126V unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [2.17.38.11] CANEFGYCSGRG# out-of-frame - in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); gcctctggtttcacctttagtagtcatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaactattcgagccagtggcgataggacacactacgcagactccgtgAaagggccgcttcaccatctccagagacaactccaagaacacgctgtatttgcaaatgtacggcctgagagtcgaggacacggccgtatattattgtgcgaacgaattcggatactgtagtggtcgggggggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21623 JY8QFUQ01AZH1L productive Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21624 JY8QFUQ01B6TCJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21625 JY8QFUQ01CGYCC unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21626 JY8QFUQ01AN6GB No results +21627 JY8QFUQ01BZ48Y productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDLFQVSTTYFDYWG in-frame - ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggccgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactgggggcccgggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctcccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +21628 JY8QFUQ01BWN32 productive (see comment) Homsap IGHV3-9*01 F 968 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDAMGGAGDWAAFGIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 98 of V-REGION: 'A' (1 nucleotides at position 198 to 198 in the user submitted sequence), (cause frameshift); cctctggcttcatctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagcgctaccatagaatatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctggaaatcaacagtctgagacctgaaAgacacggccttatactactgcgcaaaagatgcgatgggaggagctggtgattgggctgcttttggtatctggggccaggggacaatggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21629 JY8QFUQ01CLLPW productive (see comment) Homsap IGHV3-30*01 F 992 94.57 209/221 nt 94.12 208/221 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [2.17.38.11] CAKDELPWDTIEYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift); aggcctctggattcaccttcaatacctattcGtatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21630 JY8QFUQ01C8HCR unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 412 81.97 100/122 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found Low V-REGION identity (81,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgtttctacttacaccattttctacgcagagtctgtta +21631 JY8QFUQ01B84CX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame - ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21632 JY8QFUQ01C87ZL unknown (see comment) Homsap IGHV3-7*02 F 109 59.04 49/83 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21633 JY8QFUQ01AXHEJ productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +21634 JY8QFUQ01CYK0K productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataGggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21635 JY8QFUQ01BAZB8 No results +21636 JY8QFUQ01CVQCY No results +21637 JY8QFUQ01DKYS7 unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARETLPPWCWG#FDNW out-of-frame + cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactccccccttggtgttgggggtttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21638 JY8QFUQ01AXBNA unproductive (see comment) Homsap IGHV3-7*01 F 970 93.24 207/222 nt 92.79 206/222 nt Homsap IGHJ4*03 F (see comment) 78 62.5 30/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [3.17.38.11] CAKGGW*##DLDYW out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'CAA' (3 nucleotides at position 16 to 18 in the user submitted sequence), (do not cause frameshift); gcgacctctggagttCAAccctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaagcccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +21639 JY8QFUQ01AATBN unproductive Homsap IGHV3-7*01 F 928 91.78 201/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [2.16.38.11] CVRDRLYDSSGYDFGGIGGTI#DHW out-of-frame - in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) agcctctggattcatgtttagtgactattggatgagctgggtccgccaggctccagggaagaggctgagtgggtggccaacataaggaaagatggaagtgaggcgtactatgtggaatctgtgaagggccgattcaccatctccagagacaacgccaggaactcactgtttctgcagatgaacagcctgagggccgaagacacggctgtatatttctgtgtgagagatcgtctctatgatagtagtggttatgactttgggggaattggggggactattcagaccactggggccagggaacccaggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21640 JY8QFUQ01C0I7Y productive Homsap IGHV1-24*01 F 970 95.31 203/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame + cggaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21641 JY8QFUQ01AGS4P productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 850 88.43 191/216 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tctggattcaccttcagtacctatgctatgtactggatccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21642 JY8QFUQ01B8CUG productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 885 90.65 194/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 8 8 20 8.8.20 [0.17.38.11] CTRTQFDPDYGDYETGYGMDVW in-frame - tggattcaacttccgatcttatgccatgtactgggtccgccaggccccaggcaaggggctggactgggtggcagttatttggcatgatggcagtaatcaatactatgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacattgtttctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtacgaggacgcaatttgaccctgactacggtgactacgagacggggtacggtatggacgtctggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21643 JY8QFUQ01B2K4L No results +21644 JY8QFUQ01C12M6 No results +21645 JY8QFUQ01AO83E No results +21646 JY8QFUQ01AFQ6R productive (see comment) Homsap IGHV4-4*07 F 871 90.14 192/213 nt 88.73 189/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 6 13 8.6.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'CTCACTG' (7 nucleotides at position 28 to 34 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 108 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattCTCACTGactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21647 JY8QFUQ01CT1FJ productive (see comment) Homsap IGHV3-9*01 F (see comment) 788 84.86 185/218 nt 83.49 182/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [2.17.37.11] CVKDMVAGQGLLSRFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 113 in the user submitted sequence), (cause frameshift) gcctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagGtgggtcgcgggcaGtcaactggaatcggggcaaagcattgtatgggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21648 JY8QFUQ01BLI62 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 835 88.26 188/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.37.11] CARKGLVPSMFFFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 192 in the user submitted sequence), (cause frameshift) ctctggtgggtccttcagtggttacttctGggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccgggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21649 JY8QFUQ01BHCZE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-10*02 F 2 8 8 13 8.8.13 [1.17.38.11] CAKERDNNVLPVDSW in-frame + Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcagcttcaatagttatactttgagttgggtccgccaggctccagggaaggggctggagtgggtctcagctatcagtggaacaggtgaaacaaccttctacgcggactccgtgaggggccggttcaccgtctccagagacaatttcaagaatactctgtacttgcaattgagcgacctgagagccgaagacacggccgtctattactgtgcgaaggagagagataacaatgttctgcccgttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21650 JY8QFUQ01ANOBY No results +21651 JY8QFUQ01C14UQ unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1060 100.0 213/213 nt Homsap IGHJ4*02 F 82 62.5 30/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVLGGVIL*LL## out-of-frame - stop codons tctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgttttggggggagttatcttatgactactgggggccaggggaacccctggtcaccntctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21652 JY8QFUQ01BMBTD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame - ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21653 JY8QFUQ01BXELX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccGagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21654 JY8QFUQ01CPP66 unproductive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 993 94.17 210/223 nt Homsap IGHJ4*03 F 69 60.42 29/48 nt Homsap IGHD4-11*01 ORF 2 8 10 X 8.10.X [1.17.38.11] CVRHEGTPVSDVGGYGMDV# out-of-frame + ctctggtttcacgttcagtggctctgctatgcactgggtccgccaggcttccgggaaagggctggagtgggttggccgtattagaagtaaagcttacagttccacgacagcatatgctgcgtcggtgaaaggcaggttcaccatttccagagatgattcaaagaacacggcgtatctgcacatgaacagtgtgataaccgaagacacggccgtgtattattgtgttagacatgaagggactcccgtaagtgatgtaggaggatacggcatggacgtctggggccagggtccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +21655 JY8QFUQ01CE4CX productive (see comment) Homsap IGHV3-11*01 F 844 86.94 193/222 nt 86.49 192/222 nt Homsap IGHJ6*02 F 263 94.83 55/58 nt Homsap IGHD1-26*01 F 3 8 8 11 8.8.11 [3.17.38.11] CVRDYYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'GGG' (3 nucleotides at position 100 to 102 in the user submitted sequence), (do not cause frameshift); cagcttctggggttctccttcagcgactacttcatgagttgggtccgccaggctccagggaagggactggagtgggttgcatacattagtagtagtggtGGGactactaaatactacgcagactctgtgaagggccgattcaccatctccagggacaacggcaagaattcattgtttctgcaaatggacagcctgagagtcgacgacacggccatgtatttctgtgtgagagactactattattacgggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +21656 JY8QFUQ01BENBF No results +21657 JY8QFUQ01C270Z productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 903 91.59 196/214 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-21*02 F 2 8 8 13 8.8.13 [0.17.38.11] CATIPSYCGGDCYYW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtatactactgtgcgaccatcccttcgtattgtggtggtgactgctattactggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21658 JY8QFUQ01BNI7F No results +21659 JY8QFUQ01AH4OV productive (see comment) Homsap IGHV3-7*01 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); cctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcctatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgt +21660 JY8QFUQ01BJUZZ unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 1 8 8 X 8.8.X [1.17.38.11] CAKGGGKRRP*LL# out-of-frame + stop codons ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgaccagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc +21661 JY8QFUQ01AKF0A productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaatgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21662 JY8QFUQ01B20M9 productive (see comment) Homsap IGHV3-74*03 F 851 88.07 192/218 nt 86.7 189/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'GG' (2 nucleotides at position 55 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); cctctggattcactttccacacctcctggatgGcactgggtccgccaaggtccaGGgggagggggctaatgtgggtctcacgaatcaatactgatgggagtaAacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21663 JY8QFUQ01BF9DY productive Homsap IGHV3-11*04 F (see comment) 940 93.06 201/216 nt Homsap IGHJ6*02 F (see comment) 220 83.87 52/62 nt Homsap IGHD2-2*01 F 2 8 7 22 8.7.22 [2.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BF9DY ; 8 AA in Homsap_IGHV3-11*04) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (shorter alignment but highest percentage of identity) gcctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacaacggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21664 JY8QFUQ01C2RTA unproductive Homsap IGHV4-61*02 F 875 88.69 196/221 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 10 7 X 10.7.X [1.17.38.11] CARQGDSSGPWNDY## out-of-frame + tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggattggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttttccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtg +21665 JY8QFUQ01B9OP9 unproductive (see comment) Homsap IGHV3-30*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 X 8.8.X [1.17.38.11] CVKK*PVLGHNR##YFDYW out-of-frame + stop codons ctctggattcacgttcaacatttatggtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +21666 JY8QFUQ01AU5EY unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 943 91.48 204/223 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD3-3*01 F 3 8 10 X 8.10.X [1.17.38.11] CTTDRRGSDIPPQFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggatttagtttcaanaacgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaagctgatggtggggcggcagactacggtgcacccgtgagaggcagattcaccatctcaagagatgattcaagaggcacggtgtctctgcaaatgagcagcctgaaaaccgaggacacagccatctattattgtaccacagataggaggggttcggatattccacctcaatttgactactgggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +21667 JY8QFUQ01BPRNF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 943 93.9 200/213 nt 92.96 198/213 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 7 7 11 7.7.11 [1.17.38.11] CAKEGNLGYFDDW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 3 nucleotides (from position 81 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21668 JY8QFUQ01BQM9S unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21669 JY8QFUQ01CI0N7 No results +21670 JY8QFUQ01ANAH2 productive Homsap IGHV3-48*01 F 860 88.53 193/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21671 JY8QFUQ01BB70S productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-16*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGDLPHYIDYW in-frame - tggatacatcttcaccagctactttatgcactgggtgcgacaggcccctggacaagggcttgagtggatgggaatagtcaaccctagtggagctggcacaacttacgcacagaagttccagggcagagtcaccatgaccagcgacacgtccacgaccacagtctacatggagctgagcagcctgagatccgacgacacggccatatattactgtgcgagaggcgatctcccccactacattgactactggggccagggaaccctggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +21672 JY8QFUQ01CFZB2 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 624 93.62 132/141 nt 8 8 X 8.8.X [1.17.12.X] null + No rearrangement found ctctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctc +21673 JY8QFUQ01CCNVJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +21674 JY8QFUQ01CC56Z No results +21675 JY8QFUQ01B8HFY unproductive Homsap IGHV3-7*01 F 999 95.85 208/217 nt 94.47 205/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 7 8 X 7.8.X [2.16.38.11] CAISSGYYSTGY## out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ggctctggatcagctttagttactattggatgagctgggtccgccaggctccagggaaTggggctggagtggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21676 JY8QFUQ01A5HTL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 677 78.73 174/221 nt 78.28 173/221 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found stop codons Low V-REGION identity (78,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cagcctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaAaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgcaacccggtgacggtgtcgtggaactcag +21677 JY8QFUQ01CPH1K productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggGggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21678 JY8QFUQ01A87UU productive Homsap IGHV3-48*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21679 JY8QFUQ01BZCPP unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21680 JY8QFUQ01CFWNI unknown (see comment) Homsap IGHV3-30*10 F 92 51.8 72/139 nt 8 8 X 8.8.X [1.17.12.X] null + No rearrangement found tctggattctccttcagaagttactctttccactgggtccgccaggctccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +21681 JY8QFUQ01B64QD productive (see comment) Homsap IGHV4-34*03 F 885 90.61 193/213 nt 90.14 192/213 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 228 94.12 48/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.16.38.11] CVRNYYDFSGYFNWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tgtctggtgggtccttcagtggttactactggagttggatccgccagccccagggaaggggctggagtggattggggaaatcaattatagaggaagtaccaactacaatccgtccctcaaaagtcgagtcaccgtgtcttcagacacgtccaagaatcagttctccctggagttgatctctgtgaccgccgcggacacggccatatattattgtgtgagaaattactatgattttagtggttatttcaattggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21682 JY8QFUQ01CR8IV productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 893 89.59 198/221 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 10 7 16 10.7.16 [1.17.38.11] CTNDFSMAVRATHAFHVW in-frame + tctctggtgactccattggtagtagtgcttactactggggctgggtccgccagcccccagggaaggggctcgaatggatagggaatatttactatggtggcagcacctactacaacccgtccctcaagaatcgagtcaccatatcggtagacacgtccaagaaccagctcttcctggagctgacctctgtgaccgccgcagacacggctctttattactgtacgaacgacttttcaatggcggtacgtgctacgcatgctttccatgtctggggccaagggacaatggtcgccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21683 JY8QFUQ01ADRQ3 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1057 99.07 214/216 nt 97.69 211/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [2.17.38.11] CARLGARFGD#DYW out-of-frame - stop codons in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattggGgtatatctattacagtgggagcaccaactacaaccCcctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21684 JY8QFUQ01AV6LD productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 839 86.88 192/221 nt 86.43 191/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARRHYGEGLFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); cctttggtggctccatcaccaataataattacttctggggctggatccgccagcccccagggaaggggctggagtggattgggggAtgtccagtatagtgggagcacctactccagcccgtccctcaagaggcgggtcaccatgtctgtggacgtgtccaaaagtcaggtctccctgagactgagctctgtgaccgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +21685 JY8QFUQ01B6LOD No results +21686 JY8QFUQ01CPEX7 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F or Homsap IGHV4-55*03 P 815 86.24 188/218 nt 85.32 186/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 2 9 7 15 9.7.15 [1.17.38.11] CTSREHAFSGQFTGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'TCA' (3 nucleotides at position 25 to 27 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'T' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); tgtctggtgtctccgtcaccagcgTCAgtcactggtggacctgggtccgccagcccccagggaagggactggagtggattggagaaatctattTattatggcatcaccaatttcaacccgtccctcaagagtcgaatcagcatgtcagtggacgagtccaagaaccagttctccctgagactgacttctgttaccgccgcggacacggccgtttattattgtacgagtcgcgaacatgcttttagtggtcaattcacgggtgactactggggccagggaaccctgatgaccgtcacctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21687 JY8QFUQ01CT2M9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.74 200/218 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + cctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaacccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21688 JY8QFUQ01AARZS unproductive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD6-6*01 F 2 9 7 X 9.7.X [1.17.38.11] CARDQRGRFGTSSTFDY## out-of-frame - tctctggtgactccatcagcaatgatagttggtggagttgggtccgccagcccccagggaaggggctggagtggattggggaaatctatcatactgggagcaccaactacaacccgtccctcaagagtcgagtcaccatatcactcgacaagtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacgcggccgtctattactgtgcgagagatcagcggggccgatttggcacctcgtcaacctttgactactgggggccagggagcccaggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21689 JY8QFUQ01B81XP productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 806 85.78 187/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca +21690 JY8QFUQ01CLTQ4 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1007 96.74 208/215 nt 96.28 207/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 2 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctgagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21691 JY8QFUQ01B9A9Z productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDFW in-frame + cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +21692 JY8QFUQ01BKTWV productive Homsap IGHV3-9*01 F (see comment) 788 84.86 185/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CGRIAKPGLGALDLW in-frame + Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcgttggattcacttttaatgaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctggggccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21693 JY8QFUQ01A7QH2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1085 100.0 218/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDFFIGGYYGMDVW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcatcgcctgcctggtccagggcttcttccc +21694 JY8QFUQ01B6LAE productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 955 93.15 204/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [2.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) gcctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21695 JY8QFUQ01C0PKL productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21696 JY8QFUQ01B43GE unknown (see comment) Homsap IGHV1-18*02 (F) (see comment) 614 78.22 158/202 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (78,22% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tggttatatctttaccaattatggtgtcagctgggtgcgacaggcccctggacaagggcttgaatggatgggatggataagtaatttcaatggtaacacagactatgcacagaaattccagggcagagtcaccgtgaccacagacacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21697 JY8QFUQ01AFUBY unproductive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGGW*R##LDYW out-of-frame - stop codons cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21698 JY8QFUQ01AOPB7 No results +21699 JY8QFUQ01B0X5Q unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKSPLSVAGTRQK#WFDPW out-of-frame + gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaagctggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctcccaagagcacctctgagggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21700 JY8QFUQ01C3QHH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-8*02 F 2 8 8 20 8.8.20 [1.17.38.11] CARDLWLCSGGECYHRGGFENW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift); cctctgggttcaccttcagtaactcctggatgcactGgggtccgccaagctccagggaaggggccggagtgggtctcacgtattaatagtgatgggagtaatacaatctacgcggactccgtgaagggccgactcaccatctccagagacaacgccaaaaaTcacggtgtatctgcaattgaacagtctgagagccgaggacacggctgtgtactactgtgcaagagatctgtggctttgtagtggtggtgaatgctatcatcggggtggttttgagaactggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +21701 JY8QFUQ01ANNUO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21702 JY8QFUQ01A3HRK No results +21703 JY8QFUQ01AOI6V productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21704 JY8QFUQ01ACIGX No results +21705 JY8QFUQ01B1ER9 unproductive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1011 97.2 208/214 nt 96.73 207/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [0.17.38.11] CARGTAAS##FDYW out-of-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagctactatttgcactgggtgcgacaggCcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcgagggggacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21706 JY8QFUQ01CRCLR unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 877 88.0 198/225 nt 87.56 197/225 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD4-17*01 F 3 8 10 X 8.10.X [2.17.38.11] CTTWFDDFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); gcctctggactcactttcagcaacgcctggatgagatGgggcccgccaggctccagggaggggggctgagtgggttggccgcattaaaagtaaagctgatggtgggacaacagactttgatgcagccgtgaaaggcagattcaccctctcaagagacgattcaaaaaatacgatatatctgcaaatgaatcgcctgaagactgaggacacaggtgtttattactgtaccacatggttcgacgactttgactactggggccccgggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +21707 JY8QFUQ01BVTDC unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 491 94.5 103/109 nt 93.58 102/109 nt 8 8 X 8.8.X [2.17.1.X] null + No rearrangement found in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaagGgggctggagtgggtctcatacattagtaggagtagtactgacatatact +21708 JY8QFUQ01CEJI6 productive (see comment) Homsap IGHV3-11*01 F 919 93.33 196/210 nt 92.86 195/210 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [X.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 91 in the user submitted sequence), (do not cause frameshift) ggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcag +21709 JY8QFUQ01B38K0 No results +21710 JY8QFUQ01AQSQ8 productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAYFSTGYW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21711 JY8QFUQ01AUR2T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc +21712 JY8QFUQ01AOLRD productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame - ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21713 JY8QFUQ01DXDOM productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 746 83.26 179/215 nt 82.79 178/215 nt Homsap IGHJ6*02 F 179 77.05 47/61 nt Homsap IGHD2-15*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDKVISAGRDVW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DXDOM ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 81 of V-REGION: 'G' (1 nucleotides at position 144 to 144 in the user submitted sequence), (cause frameshift); cctctggattcagtttcactggttttaccgtgatctgggtccgccaggctccaaggaaggggctggaatggatctcatccgtcactactaatggtctcacgtactacgcagactcagtagagggccgattcaacatctccaggGgacaacgccaacaatttagtgtttctgcaaatgaacagcctgagagtcgaggacactggtgtatattattgtgcgagagataaagtgatctctgccggacgggacgtctggggccaagggaccacggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccc +21714 JY8QFUQ01AJ1HB productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1025 97.67 210/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARGGGYYFVAIDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +21715 JY8QFUQ01DJUBW No results +21716 JY8QFUQ01A9NEQ unproductive Homsap IGHV1-3*01 F 831 87.85 188/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD2-8*02 F 3 8 8 X 8.8.X [0.17.38.11] CARDGYLPGNGADF## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcgtcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggcccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21717 JY8QFUQ01AJLWC productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggcgctctgaccagcggcgtgcaca +21718 JY8QFUQ01B3RQ2 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 875 88.24 195/221 nt 87.33 193/221 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD6-19*01 F 2 10 7 17 10.7.17 [1.17.38.11] CTNDHSMAVSAEGMLLMFR in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'AC' (2 nucleotides at position 55 to 56 in the user submitted sequence), (cause frameshift); tctctggtgcctccatgagcagtagtgcatactactggGggctgggtccgccagACcccccgggaagggggccggagtggattgggagtgtctactatggtgggagcacctactacaacccgtccctcaagagtcgggcctccatttctgtcgacacgtccaggaacgagttctccctgaggctgaactctgtgaccgccacagacacggctatgtattactgcacgaacgaccattcaatggcagtctctgctgaaggcatgcttttgatgtttcggggtccagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21719 JY8QFUQ01B9KDR productive (see comment) Homsap IGHV3-7*01 F 1017 96.77 210/217 nt 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 7 8 11 7.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift) gctctggattcagctttagtactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21720 JY8QFUQ01A3WOJ No results +21721 JY8QFUQ01CXBP9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 919 91.32 200/219 nt Homsap IGHJ6*02 F (see comment) 256 90.32 56/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [2.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) gcctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21722 JY8QFUQ01B0BRD unproductive Homsap IGHV3-7*01 F 963 93.58 204/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CAREQSSRGYPLDYW# out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 130 to 130 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtacttttttggtgaccngggtccgccaggctccagggaaggGggctggagtgggtggccaacataAaagcaagatggGaagtgaggcatactatgtggactctgtgaaggGgccgattcaccatctccagagacaacgccaggaactcactgtttctgcaaatgaacagcctgagaggcgacgacacggctgtctattactgtgcgagagaacaatcctcgaggggatatccacttgactactgggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagnaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21723 JY8QFUQ01A6OJI unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 706 81.02 175/216 nt 80.56 174/216 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD2-8*01 F 1 8 7 X 8.7.X [2.17.38.11] CARHLMVYALDV## out-of-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01A6OJI ; 8 AA in Homsap_IGHV3-23*01), and low V-REGION identity (81,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 121 to 121 in the user submitted sequence), (cause frameshift); gcctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggcaaggggctggagtgggtctcagtcttatttagtactggcactgcatactacgcagactccgtgAaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +21724 JY8QFUQ01BTWL3 unproductive (see comment) Homsap IGHV3-30*01 F 869 88.99 194/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDSVPRVVRGC#YHFDYW out-of-frame + stop codons Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 104 of V-REGION: 'TC' (2 nucleotides at position 218 to 219 in the user submitted sequence), (cause frameshift); cctctggattctccttcagaagttaCtcttttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttTCgtgcgagagattccgtacctcgggtcgtcagaggctgcctaccactttgactattggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga +21725 JY8QFUQ01BQQAT No results +21726 JY8QFUQ01BOQDD unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +21727 JY8QFUQ01C4Q8E unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactGggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21728 JY8QFUQ01A82HJ productive Homsap IGHV3-72*01 F 953 91.96 206/224 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 10 14 8.10.14 [1.17.38.11] CARLHYSGGWYGLDVW in-frame - cctctggattcaccttcagtgaccactacatagactgggtccgccaggctccaggaaaggggctggagtgggttggccgtactcgaaataaagctaacggttacagtacagagtatgccgcgtctgtgaaaggcagattcaccgtctcaagagataactcagagaacttagtgcatctgcaaatgaacagcctgaaaagcgaggacacggccctgtattactgtgctagactgcactacagtggtggctggtacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21729 JY8QFUQ01CFHNB unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 703 80.37 176/219 nt Homsap IGHJ1*01 F (see comment) 107 67.31 35/52 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [2.17.38.11] CARGLGLNAVYAFDV## out-of-frame + Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctctggattcgcttttggagattatgccatgaactgggtccgccaggccccagggaagggactggagtgggtctcaggtttgagcggtagaggcgtcagcaaatattatgcagactccgtgaggggccggttctccatttccagagacaactccgggagcgaggcagtccttcaaatgagcagcctgagagtcgaggacacggccacttactactgtgcgaggggcctagggcttaatgctgtctacgcatttgacgtctgggggacaggggaccacggtcaccgtctcctcagcatcccccgaccagccccaaagggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21730 JY8QFUQ01ARH62 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgatccagggcttcttcccc +21731 JY8QFUQ01A5GKO productive Homsap IGHV1-2*02 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARGVKSSAWHFDHW in-frame + tggatacaccttcatcggcaactatgttcactgggtgcgacaggcccctggacaagggcttgagtggatgggctgggtcaaccctaacagtggtagcacaaactttgcacagaagtttcagggcagggtcaccatgaccagggacacgtccatcaccacagtctccatggagctgaacagcctgagatctgacgacacggccgtgtattactgtgcgagaggggtgaagagcagtgcctggcactttgaccactggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21732 JY8QFUQ01DB7HM unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 120 66.67 40/60 nt 8 X X 8.X.X [2.10.X.X] null + No rearrangement found gcctccggattcacctttagtagttactggatgcactgggtccagggcttcttcccccca +21733 JY8QFUQ01DK9P4 No results +21734 JY8QFUQ01CPA3N productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 973 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggGggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21735 JY8QFUQ01COXPE productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 883 89.5 196/219 nt 88.58 194/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [2.17.38.11] CARDFFIGGYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); gcctctggattcagctttttcaattatggGcatgaactgggtccgccaggctccagggagggggctggagtgggtcgcatttattagcggtgctggtGaaaaatacttactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21736 JY8QFUQ01AF78T No results +21737 JY8QFUQ01B4MAM productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 994 93.78 211/225 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 142 76.0 38/50 nt Homsap IGHD2-15*01 F 2 8 10 17 8.10.17 [2.17.38.11] CAADGCPGGTCYHGFLICG in-frame - gcctctggattcactttcagtaacgtctggatgcactgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgctggtggggcaacagaatacgctgcgcccgtgagaggcatattctccatctcaagagatgattcaaagaacacgttgtatctgcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtgccgcagatggttgtcctggtggtacctgctatcatgggtttttgatatgtgggggccaagggacaatggtcaccgtctcttcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +21738 JY8QFUQ01AZKCA productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [3.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION in FR2-IMGT at codon 48 of V-REGION: 'C' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); tgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggCaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21739 JY8QFUQ01CFD8X unproductive Homsap IGHV3-7*01 F 1049 98.17 214/218 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDPYSSGRGTFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctttagtttctattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatccgtatagcagtggccgggggacttttgactactggggccaggggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21740 JY8QFUQ01BGQBS unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 928 91.78 201/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [2.17.38.11] CARGDGYDTFDYW# out-of-frame + in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); ggttcaggatacgactttcccacctactggatcggctgggtgcgccagatgccCcggcaaaggcctggagtggatggGggatgatgaatcctgaagactctgacaccagatacagtccgtccttcccaggccaggtcaccatctcagtcgacaagtccatcagcaccgcctacctgcagtggagcagcctcaaggcctcggacaccggcatgtatttctgtgcgagaggcgatggctacgatacctttgactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21741 JY8QFUQ01CCWP5 No results +21742 JY8QFUQ01CN1M1 productive Homsap IGHV3-7*01 F 885 90.65 194/214 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD4-23*01 ORF 3 8 8 12 8.8.12 [0.17.38.11] CARGTSVDPGIDHW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tggattcacctttagtaattattggatgcactgggtccgccaggtttcagggagggggctggagtgcgtggccaccataaacgaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactctctgtttttgcagatgaacagcctgagagccgaggacacggctgtctactactgtgcgagagggacctcagtggacccggggattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21743 JY8QFUQ01CDCEV productive (see comment) Homsap IGHV3-66*02 F 898 91.55 195/213 nt 90.61 193/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.16.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) ctctggattcaccgtcagtagcagcttcatgacttgggtccgccagctccaggaaagggactggagtAgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcagg +21744 JY8QFUQ01BZ5ZM unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYFGTL#DYW out-of-frame + stop codons in CDR1-IMGT at codon 35 of V-REGION: 'T' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); ggtctggattcatcttctTgaaaatatggcatgcactgggtccgccaggctccaggcaaggGggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttggaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +21745 JY8QFUQ01CNIDY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 913 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 76 to 78 in the user submitted sequence), (do not cause frameshift); tcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21746 JY8QFUQ01CW2YY productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 915 90.91 200/220 nt 89.09 196/220 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'GG' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); ggcctccggattcacctttagtagttactggatgcactgggtccgccGaagctccagGGggagggactgggtctgggtctcacggactaatgaagatgggagtatcacGaaactacgAcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21747 JY8QFUQ01B5TR2 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 866 87.78 194/221 nt 87.33 193/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-14*01 ORF 2 8 10 13 8.10.13 [1.17.37.11] CTADVPSPLAQNDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 165 in the user submitted sequence), (cause frameshift) tctggattcactttcaatggcgcctggatgaactgggtccgccaggctccagggaagggtctggagtgggttgcccgtataaaaacttttggtgaaggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcaaaaaaaggctgtatctgcagatggacagcctgagaatcgaggacatagccaagtattactgcaccgcagatgtcccgtcaccattagcgcaaaatgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21748 JY8QFUQ01A87BG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGHSYYVSSGPDYW in-frame + cctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggcatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +21749 JY8QFUQ01A1ISV productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21750 JY8QFUQ01B9VDC productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); ctctggattcaTcgttcagtagctactggatgcactgggtccgccaagctccCagggaaggggctggtgtgggtgtcacgtagtaataCcgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +21751 JY8QFUQ01CEUXK unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 564 78.69 144/183 nt 8 8 X 8.8.X [1.17.26.X] null + No rearrangement found Low V-REGION identity (78,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccgaaccggtgacggtgtcgtggaactcag +21752 JY8QFUQ01CBWNJ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 744 82.27 181/220 nt 81.82 180/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARQSEPANNFNDPSRYFFDTW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); tctccgtgtctccatttccattaatgattactactGggggctggatccgccagcccccaggaaagccgctggagtggattgggactgtccattcccttgggtacaattacaacaacccgtccctcaagagtcgactcaccatttccgcagacacgtccaggaatcagatctccctgaaactgacgtctgtgaccgccgcagacacggctgtctatttctgtgcgagacagagcgagcccgccaataacttcaatgacccaagtcgttatttctttgacacttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21753 JY8QFUQ01BS8WW unknown (see comment) Homsap IGHV3-72*01 F 407 97.65 83/85 nt 8 1 X 8.1.X [2.17.X.X] null + No rearrangement found gcctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtacta +21754 JY8QFUQ01CSDEG productive Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattccccttcaatatatggagcatgaattgggtccgccaggctcccgggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcgggtctttcccccctgggcgccctgctccagggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21755 JY8QFUQ01ADDIY unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 874 89.04 195/219 nt 87.67 192/219 nt Homsap IGHJ1*01 F 98 65.38 34/52 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKDQSCIVGPCGF*LLG in-frame + stop codons in FR3-IMGT at codon 91 of V-REGION: 'CG' (2 nucleotides at position 180 to 181 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 98 of V-REGION: 'G' (1 nucleotides at position 203 to 203 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'T' (1 nucleotides at position 214 to 214 in the user submitted sequence), (cause frameshift); gcctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatCGaacaagcctaggggccgaggaGcacggccgttTtattactgtgcgaaagatcagtcctgtatagtgggaccttgtggtttttgactactgggggccaggggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21756 JY8QFUQ01CO06K productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 911 90.5 200/221 nt 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagTcccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21757 JY8QFUQ01AZZ55 productive Homsap IGHV3-7*01 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame + ggctctcgattcaccttcagtggttattggatgaactgggtccgccagactctagggaaggggctggagtgggtggccagcataaaccaagatggaagtgagacgtcctatgtgggctctgtgaagggccgattcgccatctccagagacaacgccaagaactctctgtatctgcaaatgaatagcctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtctttccgctgagcctcctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +21758 JY8QFUQ01DXAUT unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F (see comment) 449 72.47 129/178 nt 71.91 128/178 nt 8 8 X 8.8.X [1.16.25.X] null + No rearrangement found Low V-REGION identity (72,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaagggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21759 JY8QFUQ01BMBCR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 874 89.04 195/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - gcctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +21760 JY8QFUQ01AEYNO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21761 JY8QFUQ01BUAFC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggacacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21762 JY8QFUQ01ATMMU productive (see comment) Homsap IGHV3-48*02 F (see comment) 730 81.28 178/219 nt 80.82 177/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [2.17.38.11] CARSTDGYYDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift); gcctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggGAaggggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21763 JY8QFUQ01AEF82 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 10 9 19 10.9.19 [0.17.38.11] CARGSSRGGNSDGVYYELDYW in-frame - ccggggacagtgtctctaccacccgtgctgcttggaactggatcaggcagtccccatcgggaggccttgagtggctgggaaggacatactacaggtccaagtggcttaatgattatgcagtgtctgtgaaaagtcgaattaccatcaatccagacacatccaagaaccagttttccctgcagttgaaatctgtcattcccgaggacacggctgtttattactgtgcaagaggttccagtcgcggggggaattctgatggggtctactatgaacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +21764 JY8QFUQ01AXKXP unproductive (see comment) Homsap IGHV3-21*03 F, or Homsap IGHV3-21*04 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CHRHGPRGWEATW##DYW out-of-frame + stop codons cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacaacctgagaaccgaggacacagccctttattactgtcaccgacacggcccccgggggtgggaagccacttggccttgactactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +21765 JY8QFUQ01CENHS No results +21766 JY8QFUQ01BMQAP productive (see comment) Homsap IGHV4-61*01 F 988 94.14 209/222 nt 93.69 208/222 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [2.17.38.11] CARGGSGGAYWNLIRDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 67 of V-REGION: 'TATAATCCCCTG' (12 nucleotides at position 112 to 123 in the user submitted sequence), (do not cause frameshift); gtctctggtggctccgtcagcagagatatttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatgtatcacagagggaacactaagTATAATCCCCTGtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtgggtccggtggggcctactggaatttgatccgggactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21767 JY8QFUQ01C39EW productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21768 JY8QFUQ01C1K4A No results +21769 JY8QFUQ01B50E3 unproductive (see comment) Homsap IGHV3-30*01 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 X 8.8.X [2.17.38.11] CVKK*PVLGHNR##YFDYW out-of-frame + stop codons gcctctggattcacgttcaacatttatggtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21770 JY8QFUQ01AO9MS productive (see comment) Homsap IGHV2-5*02 F 1111 95.47 232/243 nt 95.06 231/243 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-17*01 F 3 10 7 13 10.7.13 [9.17.38.11] CAHFSVTTPYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift); gacctcacgctgacctgcaccttctctgggttctcactcaccactactggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcagtcaCttttttgggatgatgatgagcgccacagcccatctctgaggagaaggctcaccatcaccaaggacatctccaaaaaccaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacttttcggtgactaccccatatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21771 JY8QFUQ01B8IT3 productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21772 JY8QFUQ01B61YA No results +21773 JY8QFUQ01DGCRI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD3-9*01 F 2 8 8 18 8.8.18 [1.17.38.11] CVKVAGDYRTPNYGWHFDLW in-frame + cgtctggattcaccttcagtagctacggcatgcactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggtagtggtggcagcacattctactcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactggatctgcaaatgaatagcctgagaggcgaagacacggccgcatattactgtgtgaaagtggccggtgactatagaactcccaactacggctggcacttcgatctctggggccgaggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21774 JY8QFUQ01B949V unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 987 94.55 208/220 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [2.17.38.11] CVRRGDGSGQ##DAFDIW out-of-frame - stop codons agcctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaaggggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtatcgtggaactcag +21775 JY8QFUQ01CA2MY productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1085 100.0 218/218 nt 99.54 217/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21776 JY8QFUQ01CDL2M unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CARPFSGRWCFDL## out-of-frame - Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) cctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctgggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21777 JY8QFUQ01CDJGM unproductive Homsap IGHV4-28*01 F, or Homsap IGHV4-28*02 F or Homsap IGHV4-28*03 F or Homsap IGHV4-28*05 F or Homsap IGHV4-28*07 F or Homsap IGHV4-39*07 F or Homsap IGHV4-4*06 F or Homsap IGHV4-55*03 P (see comment) 391 77.04 104/135 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 228 94.12 48/51 nt Homsap IGHD3-22*01 F 2 X 7 X X.7.X [X.X.38.11] CVRITMILVVI#NWFDSW out-of-frame - Low V-REGION identity (77,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctggtgggtcccttcagtggttactacaatccgtccctcaaaagtcgagtcaccgtgtcttcagacacgtccaagaatcagttctccctggagttgatctctgtgaccgccgcggacacggccatatattattgtgtgagaattactatgattttagtggttatttcaattggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21778 JY8QFUQ01AJN2L unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1031 97.25 212/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CVVQILGGY##DYW out-of-frame + stop codons cctctggattcaccttcaatacctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtggtagtacttacataaagtacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtggtccagatcctagggggctacgattgactactggggccagggaaccccggggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21779 JY8QFUQ01CBAA4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 256 90.32 56/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21780 JY8QFUQ01A34CF productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 810 85.78 187/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDTGSSKFARYDGMDVW in-frame + cctctggattcagcctcagtacctctggcttgaactgggtccgccaggccccagggaagggantggagtggatctcattcatcaatagtgatggtgattacatctactacgcggagtcggtgaggggccgattcaccatctccagagacaacgccgagaagtcactgtacctgcaactgaacaacctgagagtcgaggacacggctgtgtacttctgtgcgagagataccggctcgtccaagttcgctaggtacgacggtatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgcctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +21781 JY8QFUQ01B0S2P No results +21782 JY8QFUQ01BBWB8 No results +21783 JY8QFUQ01BAECU unknown (see comment) Homsap IGHV3-7*01 F 991 94.98 208/219 nt 94.52 207/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); acctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaagccccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag +21784 JY8QFUQ01B58N4 productive (see comment) Homsap IGHV4-61*02 F 815 86.24 188/218 nt 85.32 186/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 10 6 16 10.6.16 [1.17.38.11] CAIERSRSIGGDGQFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 102 in the user submitted sequence), (do not cause frameshift) tctctggtggccccatcagaggcggtggtttctactggacctGggctccggcagtccgccgggaagggcctggagtggatcggacgtatttatgacagtggcagtgactacaatccttctctcaagagtcgagtcaccatgtcagtagacacgtccaagagccagttctccctgaggctgagttctgtggccgccgcagacacggccgtttacttctgtgcgatagaacgtagtagatcgattggcggagacggacaatttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21785 JY8QFUQ01DWR54 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 856 88.13 193/219 nt 87.67 192/219 nt Homsap IGHJ1*01 F 80 61.54 32/52 nt Homsap IGHD6-25*01 F 3 8 8 11 8.8.11 [2.17.38.11] CASFACPGKWLLG in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); gtctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggGggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttgcgtgtcctggaaagtggctactggggccaggggaacccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21786 JY8QFUQ01CNGV0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cctctggattcaccttTtaccaactatggcatgagctgggtccgccaggctccagggaaggGggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctccgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21787 JY8QFUQ01B3ZV0 No results +21788 JY8QFUQ01DKNDP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21789 JY8QFUQ01BSHOR productive Homsap IGHV3-7*01 F 918 91.28 199/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - cctctggattcaccttcagtagctatgctatgcactgggttcgccaggntccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21790 JY8QFUQ01BM1A9 productive Homsap IGHV1-8*02 F 822 87.38 187/214 nt Homsap IGHJ2*01 F 193 84.91 45/53 nt Homsap IGHD2-21*02 F 2 8 8 16 8.8.16 [0.17.38.11] CTTKFGSDWQSDWYFHVW in-frame + tggagacacattccccagccatgacatcaactgggtgcgacaggccactggagaagggcttgagtggatgggacggatgaaccctaagactggtgacacaagctttgcacagaagttccacgatagagtcaccatgatcagtgacacctccataagtacagtgtacatggagctgagtagcctgagatctgaagacacggccatttactattgtacgacaaaattcgggagtgactggcaatcggactggtacttccacgtctggggccgtggcacctcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +21791 JY8QFUQ01BY5B0 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 923 91.74 200/218 nt 90.37 197/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARRDVGLHAFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 71 of V-REGION: 'C' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); gttctggatccaattttaactacgactggatcggctgggtgcgccagatgCcccggtaaaggcctggagtgGgatgggaatggtctatgttggtgactctgatgctagatacagcccgtcctCcccaaggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgcttttgatctgtggggccaggggacaatggtcagcgtctcttcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgccctgcctggtccagggcttcttcccccc +21792 JY8QFUQ01AO74U productive (see comment) Homsap IGHV3-7*01 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATDDSNGWDEVADYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagCtccccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21793 JY8QFUQ01B3L3F productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21794 JY8QFUQ01B09FB No results +21795 JY8QFUQ01BWFI9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + cctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctaagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21796 JY8QFUQ01B083I unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +21797 JY8QFUQ01CPFCW No results +21798 JY8QFUQ01BBMA6 productive (see comment) Homsap IGHV4-61*02 F 656 90.06 145/161 nt 89.44 144/161 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 X 7 13 X.7.13 [X.8.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift); ggaagggactggaatggattgggcgcatgtctgccagagggggAcagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21799 JY8QFUQ01B45A1 productive Homsap IGHV3-7*03 F 1031 97.25 212/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARGYSYGCFDYW in-frame + cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagaggatacagctatggctgctttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagtgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +21800 JY8QFUQ01BKZZ2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAIEHTLPSGQGLGIEYFW in-frame - cctctggattcaactttaacagctttgccatgagctgggtccgccaggttccagggatggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactccgtgaagggccggttcaccatctccagagacaactccaacaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgatcgagcatacccttccgtccggacagggattagggattgaatatttctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21801 JY8QFUQ01BG0RX unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggGggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactgggggccagggaacccgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21802 JY8QFUQ01ACXSL productive (see comment) Homsap IGHV4-34*10 F 809 86.51 186/215 nt 85.58 184/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AA' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift); tgtctggtgagtGccttcactaattactactggagctggatccgccagtcccccaggaaAAgggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21803 JY8QFUQ01AZCLU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt 95.41 208/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-10*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGAAVALTPG in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggGggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtgcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21804 JY8QFUQ01BS2II productive (see comment) Homsap IGHV4-61*02 F 928 91.78 201/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 9 7 14 9.7.14 [1.16.38.11] CAREPQSNAWYYFDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 34 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) tctctggtggctccgtcaacatggtaattctgactgagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21805 JY8QFUQ01CYFA7 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 89 51.88 69/133 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons tctggattcacctttaacatgtatgtcatgcactggttccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21806 JY8QFUQ01B4Q5E No results +21807 JY8QFUQ01AMQ7L unknown (see comment) Homsap IGHV3-7*02 F 83 55.29 47/85 nt 8 1 X 8.1.X [2.17.X.X] null + No rearrangement found gcctctggtttcagcttaagtgactattggctgccctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +21808 JY8QFUQ01AKL4Q unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccaggGgaaggggctggagtGgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21809 JY8QFUQ01BGI0O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 256 90.32 56/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21810 JY8QFUQ01BV8FF productive Homsap IGHV3-13*01 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 10 8.7.10 [1.17.38.11] CATISDYRFEFW in-frame - ctctggaatcaccttcagtgactccgacatgcactgggtccgccaagctccaggagaaggtctggagtgggtcgcagctattggaactgctggtgatacatactatgcagactccgtgaagggccgattctccattaccagagagaatgccaagaactccttgtttcttcaaatgaacagcctgagagccgacgacacggctatttattactgtgcgaccattagtgactaccgatttgaattctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21811 JY8QFUQ01A7ZX0 unproductive (see comment) Homsap IGHV4-61*02 F 915 90.91 200/220 nt 90.45 199/220 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 X 10.7.X [1.16.38.11] CAREK**SV#NWFDPW out-of-frame - stop codons in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) tctctggtgactccatcaccagtggtaattattattggagttggatcggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggatcaccaactacaatccctccctcaagagtcgagtcaccatactattagacacgtccagcaaccggttctccctgaagctcagctctgtgaccgccgcagacacggccgtgtattactgtgcgagagaaaagtagtgatccgtcccaattggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21812 JY8QFUQ01A25XG No results +21813 JY8QFUQ01C3UGX productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CTRQTGNYYYFGVDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'A' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); gcctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggAaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21814 JY8QFUQ01B9QOB productive (see comment) Homsap IGHV1-18*01 F 840 88.32 189/214 nt 87.85 188/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 14 8.8.14 [0.17.38.11] CVRDSRHKFGAHFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggttacaccttgaccagcactggtttcagttgggtgcgacaggCcccctggacaagggctcgagtggatggcatggatcagcgtttacgatgatgacacaagttatgcacagaagtttcagggcagggtcaccctgaccacagacacactcacgaacacagcccacatggagctgaggagcctgaattctgacgacacggccgtgtacttctgtgtgagagatagtcgacacaagtttggtgcccactttgacctctggggccagggaaccctggtcatcgtcgcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21815 JY8QFUQ01DPTEF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); cctctgggctcagcgtcagtaactaccgcatgggctgggtccgccaggctccagggaaggggctggtttgggtctcacgtgttaatggtgatgGggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +21816 JY8QFUQ01DHC6Q unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 932 92.2 201/218 nt 91.28 199/218 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD7-27*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDQSLGMPEA#FDIW out-of-frame - stop codons in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 214 to 214 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtcgctatagcatgaactgggtccgccaggGctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatatTtactgtgcgagagatcaaagtctggggatgcccgaggctttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21817 JY8QFUQ01B31VW unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARDCDSGECNFDYW in-frame - stop codons in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); tctgattcagcttcagtacctaGtaacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21818 JY8QFUQ01ARWZ0 productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21819 JY8QFUQ01B3JUB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAEKKHYNSGTYLYNFDYWG in-frame - ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcggaaaaaaaacattataattcggggacttatttatacaactttgactactgggggccgggggaacccctggtcaccgtctcctcagcatcccccgcagccccaaggccagttcctccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag +21820 JY8QFUQ01ANE3L productive (see comment) Homsap IGHV3-30*01 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [1.17.38.11] CVKNDLSWGTIEHYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcacgttcaacatttatgGgtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21821 JY8QFUQ01B43FE unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21822 JY8QFUQ01CT6XX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDCDSGECNFDYW in-frame + gcctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21823 JY8QFUQ01A95B1 unknown (see comment) Homsap IGHV1-2*02 F 494 85.71 114/133 nt 8 8 X 8.8.X [0.17.11.X] null + No rearrangement found tggatacattttcaccagctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaacc +21824 JY8QFUQ01CX6GI productive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1105 100.0 222/222 nt Homsap IGHJ6*01 F (see comment) 108 63.49 40/63 nt Homsap IGHD6-6*01 F 2 8 10 16 8.10.16 [1.17.38.11] CTRRSIADNFYYYGMDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tctgggttcaccttcagtggctctgctatgcactgggtccgccaggcttccgggaaagggctggagtgggttggccgtattagaagcaaagctaacagttacgcgacagcatatgctgcgtcggtgaaaggcaggttcaccatctccagagatgattcaaagaacacggcgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtactagacggagtatagcagataacttctactactacggtatggacgtctgggggccaagggaccacagtcaccgtctcctcagcttccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctctggggggcacagcggccctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21825 JY8QFUQ01B2OA5 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD6-6*01 F 1 8 8 20 8.8.20 [1.17.38.11] CARDDSRLWSSSFNHYFAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); gtctggattcaccttcagttcctatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtttgatggaagtaataaatactacgcagactctgtgaagggccgattcaccgtctccagagacgatgccaagaattcacttTtttctgcaaatggacagcctgagagacgacgacacggctgtatattactgtgcgagagacgattcacggctgtggagctcgtcatttaaccactatttcgctatggacgtctggggccaagggaccaccgtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc +21826 JY8QFUQ01B1VUD productive Homsap IGHV3-11*01 F (see comment) 765 83.87 182/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctctgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21827 JY8QFUQ01CVGHB productive Homsap IGHV3-66*02 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.17.38.11] CAKLADTGEWSNRIFYFW in-frame - cagcctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcgggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctggggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +21828 JY8QFUQ01A4E73 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 906 90.45 199/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDLYGADDLW in-frame + aacctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccc +21829 JY8QFUQ01BB4SZ productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +21830 JY8QFUQ01B9PP2 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 893 89.59 198/221 nt 88.69 196/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 3 9 7 X 9.7.X [2.17.38.11] CVRPDNYFGSGEC#WMDPW out-of-frame - in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) gtctctggtggctccatcagcagtgataatttctatggggctggatccgccagcccccagggaagggactgcatggattggggaCttttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcgggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21831 JY8QFUQ01C46LG unproductive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*05 F 975 95.33 204/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [0.17.38.11] CAGDRGPVLG*FI*AK#YGLDVW out-of-frame - stop codons tggatacaccttcaccaactactatcttcactgggtgcgacaggcccccggacaagggcttgagtggatgggacggatcaacccaaacagtggtggcacaacctatgcacagaagtttcagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgagcaggctgagatctgacgacacggccgtctattactgtgcgggagatcggggtccggttttggggtgattcatataggccaaatctacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21832 JY8QFUQ01BEZGO No results +21833 JY8QFUQ01BRFS8 productive (see comment) Homsap IGHV4-4*07 F 890 90.7 195/215 nt 89.3 192/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 7 13 8.7.13 [1.17.38.11] CARDFGGSYNLVAYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'TGATTC' (6 nucleotides at position 23 to 28 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagTGATTCtcactactggagttggatccggcagcccgccggGgaagggactggagtggattgggcgtgtctacgccagtgGggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaact +21834 JY8QFUQ01CYBYL unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 417 82.11 101/123 nt 8 8 X 8.8.X [1.17.6.X] null - No rearrangement found Low V-REGION identity (82,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgtttctacttacaccattttctacgcagagtctgtta +21835 JY8QFUQ01DJK0S No results +21836 JY8QFUQ01BN7DA productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 962 92.41 207/224 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.38.11] CTHLREEMSYEW in-frame + cctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +21837 JY8QFUQ01CD92H productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 1 8 8 11 8.8.11 [1.17.38.11] CVRHTAMERGDYW in-frame - gttctggatatgactttatcaactactggatcggctgggtgcgccagatgcccgggagaggcctggaatggatgggaatcatctttcctgatgactctgatgccagatatagtccgtccttccagggccacgtcaccatctcagccgacaagtccacaagcaccgcctacctggagtggagcagcctgaaggcctcggacaccgccatctactactgtgtgagacatacagctatggagaggggtgactactggggcccgggaaccctggtcaccgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21838 JY8QFUQ01CBOGY unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPPWCWG#FDNW out-of-frame + stop codons ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactccccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcatagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaact +21839 JY8QFUQ01AM5NO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + cctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21840 JY8QFUQ01CQ1OX productive (see comment) Homsap IGHV4-34*06 F (see comment) 682 80.19 170/212 nt 79.72 169/212 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 7 7 14 7.7.14 [1.17.38.11] CSRGGQSAGWHSFEAW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 38 of V-REGION: 2 nucleotides (from position 27 in the user submitted sequence), (cause frameshift) tccatggtgggtccctcagggttaccctggacctggatccgccacaccgcagagaagggactggagtggattggtcaaatcaatagtgatggaaggacaacctacaactcggccctcatgggtcgagtcaccatttcaacagacacatccaagaatcagttctcgctgactgtggtttctgttgtcgccgcggacacggcaatgtattattgttcgagaggaggccaaagtgctggctggcactcctttgaagcctggggccagggaacccaggtaatcgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21841 JY8QFUQ01B4E2J productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1045 97.72 214/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [2.17.38.11] CARPYCGGDCHNRGAFDIW in-frame - gcgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +21842 JY8QFUQ01AIYNJ productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 899 91.16 196/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - cttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatatccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +21843 JY8QFUQ01DF3OF No results +21844 JY8QFUQ01BV2DA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGIVGDTFFDY## out-of-frame - cctctggattcacctttagtaattatgccctgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggaatcagtagtagtggtgagatcccaaactacgcagactccgtgaagggccggttcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaaagggatagtgggagacactttctttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21845 JY8QFUQ01BDMNQ productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt 96.92 220/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 154 to 154 in the user submitted sequence), (cause frameshift); tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtCccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacCccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagnatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +21846 JY8QFUQ01CEB10 productive (see comment) Homsap IGHV3-13*01 F 899 91.16 196/215 nt 90.7 195/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD4-11*01 ORF 3 8 7 17 8.7.17 [1.17.38.11] CAREVTRLTVPYYLYFDLW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 97 of V-REGION: 'G' (1 nucleotides at position 192 to 192 in the user submitted sequence), (cause frameshift); tctctggaatcaccttcagtgactccgacatgcactgggtccgccaagctccaggagaaggtctggagtgggtcgcagctattggaactgctggtgatacatactatgcagactccgtgaagggccgattctccattaccagagagaatgccaagaactccttgtttcttcaaatgaacagcctgagagccGggggacacggctgtttattattgtgcaagagaggtgactagacttactgtcccctattacttatacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21847 JY8QFUQ01B8YTR No results +21848 JY8QFUQ01B61PE productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F (see comment) 785 84.16 186/221 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-9*01 F 2 10 7 11 10.7.11 [1.17.38.11] CARILDGYFFDPW in-frame - Low V-REGION identity (84,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcgacactcaaaattactactggggctggattcgccagcccccagggacgggactggagtgggttggcagtgtccgctatggcgagagcacctattacaacccgaccctcaaaagtcgactcaccatatccatagacacgtccaggagccagttatccctgagactgagttctgtcaccgccgccgacacggcagtttactactgtgcgaggatcttggatggttacttcttcgacccctggggccagggaacccacgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21849 JY8QFUQ01B53DN productive (see comment) Homsap IGHV3-7*02 F 909 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'C' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); ctctggattCcttttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaAaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +21850 JY8QFUQ01ATY9J No results +21851 JY8QFUQ01BE8PV No results +21852 JY8QFUQ01B1MG0 No results +21853 JY8QFUQ01CU1MK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21854 JY8QFUQ01CGDGF productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 878 89.45 195/218 nt 88.53 193/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); cctctggattcaGtttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgGggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +21855 JY8QFUQ01DK22N unproductive Homsap IGHV1-2*02 F 903 91.59 196/214 nt 91.12 195/214 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [0.17.38.11] CARDWGWEVRTA#DNW out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 39 of V-REGION: 'T' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); tggatacatcttcaccggctactattTtgcactgggtgcgacaggcccctggacaagggcttgagtggatgggatacatcgacccttacactggtgacacaaattatgcacagaggtttcagggcagggtctccatgaccagggacacgtccatcagtacagcctacatggaactgaacaggctgatgtctgacgacacggccatgttttactgtgcgagagattgggggtgggaagtacgcaccgctagacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtctcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21856 JY8QFUQ01AOB98 No results +21857 JY8QFUQ01BLR4V productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 822 85.65 191/223 nt 85.2 190/223 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [2.17.38.11] CVRHVRRFWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); gtctctaatgggctccatcagcCggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21858 JY8QFUQ01AT8N2 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); ctccggattcaccttTtagtagtttctggatgcactgggtccgccaagttccagGgggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatcccccgaccagccccaaggtcttccccgctgagccctcgacagcaccccccccaaagatgggaacgtggtcgtcgcatgcctggtcccaggggcttcttcccccca +21859 JY8QFUQ01B15PF productive (see comment) Homsap IGHV4-4*07 F 796 85.65 185/216 nt 84.72 183/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 8 7 18 8.7.18 [2.17.38.11] CAREDYYGSGSYGRAWFDSW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'CAGTGG' (6 nucleotides at position 21 to 26 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'CG' (2 nucleotides at position 100 to 101 in the user submitted sequence), (cause frameshift); gtctctggaggctccatcagCAGTGGaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtCGgggggtgtcgactacaacccctccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagaggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +21860 JY8QFUQ01A62EH productive Homsap IGHV3-48*01 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaaggggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21861 JY8QFUQ01BWYQ7 productive (see comment) Homsap IGHV4-61*02 F 885 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-22*01 F 2 8 7 15 8.7.15 [1.17.37.11] CSRSLPRGYYYYGVGIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'TGGAAA' (6 nucleotides at position 23 to 28 in the user submitted sequence), (do not cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) tctctggtggctccatcggtagTGGAAAttattactggagctggattcgacagaccgccggaaagggactggagtggattgggcggatatatagtactgggagcaccgactacaaccctccctcaacagtcgagtcaccttgtccatggacacgtccaagaaccagttctccctgaaactgggctctgtgaccgccgcagacacggccgtctattactgttccaggtctcttccacgaggctactactactatggtgtgggcatctggggcccagggaccacggtcgtcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21862 JY8QFUQ01B0YB2 unproductive Homsap IGHV3-7*01 F 945 93.09 202/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt 8 8 X 8.8.X [1.17.38.11] CTTTLVWFGGV (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION in FR2-IMGT at codon 41 of V-REGION: 'A' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); ttctggattcacgtttagagactattggatgagttAgggtccgccAaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcgggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21863 JY8QFUQ01BD1TQ No results +21864 JY8QFUQ01BD0RY unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 169 58.78 77/131 nt 8 7 X 8.7.X [1.17.10.X] null + No rearrangement found ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +21865 JY8QFUQ01DW455 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 91 51.82 71/137 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found stop codons cctctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccga +21866 JY8QFUQ01CAEH2 unproductive (see comment) Homsap IGHV4-59*03 F 895 90.74 196/216 nt 88.89 192/216 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [2.17.38.11] CARGHFDSSGYSNPLDH## out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 41 of V-REGION: 'TGG' (3 nucleotides at position 38 to 40 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'CG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 97 to 102 in the user submitted sequence), (do not cause frameshift); gtctctggtgtctccatcagtagtttctactgggagtTGGgatgagggcagcccccaggggaCGgggactggGagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttctttccca +21867 JY8QFUQ01AEPDI unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 991 94.98 208/219 nt 94.06 206/219 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD2-8*01 F 3 8 8 X 8.8.X [2.17.38.11] CARDRGCGNGACHVADY## out-of-frame + in FR2-IMGT at codon 50 of V-REGION: 'CC' (2 nucleotides at position 64 to 65 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaaggggCCctggagtgggtctcatccatcagtagtggtggtagtttcaAaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21868 JY8QFUQ01ATI3N No results +21869 JY8QFUQ01ANKC4 productive (see comment) Homsap IGHV3-11*01 F (see comment) 774 84.33 183/217 nt 83.87 182/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.16.38.11] CARDLVGSIGSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaagggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccagacggtccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21870 JY8QFUQ01C0TUQ productive Homsap IGHV3-30*01 F 878 89.45 195/218 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [1.17.38.11] CACGHMRDGYDVW in-frame - cctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21871 JY8QFUQ01ABDZ0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtagttttgccatgacctgggtccGgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21872 JY8QFUQ01BSSMW unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 989 93.75 210/224 nt 92.41 207/224 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 3 10 9 X 10.9.X [0.17.38.11] CARGGDYYDSGGLDY## out-of-frame - in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); tcggggacagtgtctctagcagcagtgttgtttggaactggGatcaggcagtcCcccattgagaggccCttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtgattattatgatagtggtggtcttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +21873 JY8QFUQ01BBLDK unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 186 97.44 38/39 nt 8 X X 8.X.X [2.3.X.X] null + No rearrangement found gcctctggattcatcttcagtagctactggatgcactgg +21874 JY8QFUQ01BEFQG productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 818 86.98 187/215 nt 85.58 184/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARADYYDTSAYYLDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'A' (1 nucleotides at position 187 to 187 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 60 of V-REGION: 8 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) ctctgggtacagcttcggaggctcttgtttgcactgggtccgccaggcTttccgggaaaggactggagtgggttggccgtgtgcggaaggcagggcgcgacaacatacgctgcgtcggtgaaaggcaggttcctcatctccagagatgatccagcgaacacggcttatctggaaatgaacagcctgAaaaaccgaggacacggccgtctattactgtgctcgcgcagattactatgatactagtgcttattatctcgatgcttttgatatctgggccagggggacaattgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21875 JY8QFUQ01BXPJG No results +21876 JY8QFUQ01B4LZY No results +21877 JY8QFUQ01ASUXV productive (see comment) Homsap IGHV4-61*02 F 956 92.76 205/221 nt 92.31 204/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcaacagtggtaAttttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21878 JY8QFUQ01BD538 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 97 66.0 33/50 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRRGMVAGRYDAFDI## out-of-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctgggggccgagggactatggtcaccgtctctccagcctcaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +21879 JY8QFUQ01ANHZW productive (see comment) Homsap IGHV4-61*02 F 972 90.64 213/235 nt 89.36 210/235 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [6.16.38.11] CAREHSRTMGGARELDSW in-frame - Potentially, because of detected insertion/deletion in FR1-IMGT at codon 26 of V-REGION: 'C' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) ccctcacctgcactgtcCtctggtggccccatcagcagtggtGacttactactggacttggatccggcaggccgccgggagggactggagtggatcggacgtgtttatattagtgggagcactacctacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgccgctgacacggccgtatattactgtgcgagagaacatagtaggacgatgggcggggcgagagagcttgactcctggggcctgggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21880 JY8QFUQ01A9M6A unproductive Homsap IGHV3-7*01 F 1007 96.74 208/215 nt 96.28 207/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [0.17.38.11] CARNTPAYWELSGD## out-of-frame + in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); ctggattcacctttaggagttattggatcagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccCcagatggaagtgagaaatactatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgcgcgaaatacaccggcgtattgggaactatcaggtgactggggtccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21881 JY8QFUQ01CTIHR No results +21882 JY8QFUQ01BTGOM unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 265 100.0 53/53 nt 98.11 52/53 nt 10 X X 10.X.X [1.6.X.X] null + No rearrangement found in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactggGggctggatccgccag +21883 JY8QFUQ01DXGB9 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 913 91.67 198/216 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CASDLGGQKSY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21884 JY8QFUQ01A4UYU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.45 195/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 8 8.8.8 [1.17.38.11] CAQRNSFDYW in-frame - cctctggattcacctttaacacctatgccatgaactgggtccgccaggctccagggaagggactggagtgggtttcaggtattagtgggagtggtgatgccgtaaactacgcagactccgtgaggggccggttcaccatctcccgagacaactccaagaatatattgtatctgcaaatggacagcctgagagccgaggacacggccatatattactgcgcgcaacgaaattccttcgactactggggccagggaaccctggtctccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21885 JY8QFUQ01B0S0Q unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F (see comment) 279 60.1 119/198 nt 10 9 X 10.9.X [1.17.29.X] null - No rearrangement found stop codons Low V-REGION identity (60,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tccggggacagtgtctctagcaacagtcctgcttgagactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag +21886 JY8QFUQ01AF30Y productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 872 89.77 193/215 nt 87.91 189/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); ctctggggttcaccgtcagtagcaagttcatgagctgggtccgccaggGgtccagggaaggggctggagtggGgtctcagGttacttatcctgCatggtactacacattatagagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgc +21887 JY8QFUQ01BKUFH unproductive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 960 93.18 205/220 nt 92.27 203/220 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-23*01 ORF 3 9 7 X 9.7.X [2.17.38.11] CASHGGKYFPQ## out-of-frame + in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 174 to 174 in the user submitted sequence), (cause frameshift); tgtctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcCccccagggaaggggctggagtggattggacaaatccatcatggtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccCctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcacccctggtcaccgtctcctcagcatcccccggaccagcccccaaggtcttcccgctgagcctcgacagcacccccccctaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag +21888 JY8QFUQ01DWIIJ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1040 97.71 213/218 nt 97.25 212/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [2.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21889 JY8QFUQ01ADED3 productive Homsap IGHV3-13*01 F 961 94.84 202/213 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + tctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21890 JY8QFUQ01AR8QA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARDRLTISALDY## out-of-frame + in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 177 to 177 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaAatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +21891 JY8QFUQ01B1JAF productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +21892 JY8QFUQ01AQ55A productive (see comment) Homsap IGHV4-61*02 F 938 91.86 203/221 nt 90.5 200/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARATLSDVDTPLGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift); tctctggtgtctcaatcacgagtggaagtcactactggaattggattcggcagCcccgccgggaagggaccggagtggattgggcgTtttctataccagtgggagcaccaactacaaccCcctccctcaagagtcgagtcaccgtatcagcagacacgtccaagaaccggctctccctgaagctgagatctttgaccgccgcagacacggccgtttattactgtgcgagagcaaccttgtctgacgtggatacacctttgggctttgactactggggccagggaatcttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +21893 JY8QFUQ01BZZ8D productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +21894 JY8QFUQ01ARR9X unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1031 97.25 212/218 nt 96.79 211/218 nt Homsap IGHJ1*01 F 89 63.46 33/52 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKEFGEGP*LGTTTSTFTT## out-of-frame + stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacgttcagtggctatggcatgcactgggtccgccaggctccaggcaaggGggctggagtgggtggcagttgtatcatatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctctctctgcaaatgaacagcctgagagctgaggacacggctgtatattactgtgcgaaagaatttggggagggcccctgactgggaactactaccagtactttcactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21895 JY8QFUQ01DOYAQ unproductive Homsap IGHV3-7*01 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CARSGSGSHL#DYW out-of-frame + in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctctggattcacctttagtaGgtttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttaggattactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +21896 JY8QFUQ01AY3KG No results +21897 JY8QFUQ01AQW6B productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 905 90.83 198/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame - ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21898 JY8QFUQ01COEKL No results +21899 JY8QFUQ01BSH4H unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 222 87.72 50/57 nt 8 X X 8.X.X [1.9.X.X] null + No rearrangement found cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccaggga +21900 JY8QFUQ01DP2RP productive (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F 897 91.94 194/211 nt 91.47 193/211 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 2 7 8 16 7.8.16 [X.17.38.11] CTRGIAVGASHEASFDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) gattcagcttgatgattttgtcatgcactgggtccggcaagttccagggaagggcctggagtgggtctcaagtattacttggaatagtggtaagattgtctatgcggactctgtgaagggccgattcaccatctccagagacaacgcccagaactccctgtatctgcaaatgaacagtctacttactgaggacacggccttatattactgtacaaggggtatagctgtaggtgcctcccacgaggcgagttttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21901 JY8QFUQ01BVFVQ unknown (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1015 95.5 212/222 nt 95.05 211/222 nt 8 10 X 8.10.X [1.17.37.X] null + No rearrangement found in FR3-IMGT, from codon 96 of V-REGION: 2 nucleotides (from position 198 in the user submitted sequence), (cause frameshift) cttctggattcacctttggtgattatagtatgagttggttccgccaggctccagggaaggggctggagtggatcggtttcattagaagcaaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaccgggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttacctttgactcctgggccagggaaccctagtcaagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcancacccagccagatgggaacgtgtcatcgctgcctggtcagggcttcttcc +21902 JY8QFUQ01BD4IE productive (see comment) Homsap IGHV3-11*01 F 973 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggGggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcactatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +21903 JY8QFUQ01AVU2V productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 877 89.81 194/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + tccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca +21904 JY8QFUQ01BBGN6 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-30*01 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*04 F or Homsap IGHV3-30*05 F or Homsap IGHV3-30*07 F or Homsap IGHV3-30*09 F or Homsap IGHV3-30*10 F or Homsap IGHV3-30*13 F or Homsap IGHV3-30*14 F 103 88.46 23/26 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found cctctggattcaccttcggaacctat +21905 JY8QFUQ01AWJKB unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 719 85.28 168/197 nt 84.26 166/197 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) tctgtggtgggtccttcagtggtttctactagagatgcatccgccagcCccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +21906 JY8QFUQ01BE00R unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggccttcttccccca +21907 JY8QFUQ01C21Q2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [2.17.38.11] CAKDGMMTFWGELSSPVG#FFDYW out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGcatttggtgactatgtcatgagctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtagcggtggaactacatattatgcagactccgtgaagggccggttcaccatttccagagacaactccaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgaaagatggaatgatgacgttttggggggagttatcgtccccagtaggttcttctttgactactggggccagggagccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +21908 JY8QFUQ01ASVZA productive Homsap IGHV3-9*01 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame + cctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21909 JY8QFUQ01B5K1V unproductive Homsap IGHV3-7*01 F 995 95.41 208/218 nt 93.58 204/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.16.38.11] CAISSGYYSTGY## out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 38 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) aggctctggattcagctttagttactattggatgagcgggtccgccaggctccagggaaTggggctggagtggtggccaacataaaggGaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgaaagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +21910 JY8QFUQ01BWZW5 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ2*01 F (see comment) 85 62.26 33/53 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKG#LG out-of-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgCtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccaggggagtcctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21911 JY8QFUQ01B8AN9 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift) cctctggattcaCcctttggttattatggcatgactgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21912 JY8QFUQ01CLEGR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CARAYSGPGPYYFDYW in-frame + cctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca +21913 JY8QFUQ01B3IKP productive (see comment) Homsap IGHV4-61*02 F 986 94.95 207/218 nt 93.58 204/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 9 7 11 9.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'CTA' (3 nucleotides at position 25 to 27 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 3 nucleotides (from position 24 in the user submitted sequence), (do not cause frameshift) tctctggtgggtccatcagcagtaCTAgttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaaccCcctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21914 JY8QFUQ01A9619 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1013 98.56 206/209 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-17*01 F 2 6 8 16 6.8.16 [X.17.38.11] CARQLDYGDYSRHGLDVW in-frame + acaactttaccggctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccgtgtattactgtgcgagacaattagactacggtgactactctaggcacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc +21915 JY8QFUQ01BNQPR productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGVVTATLTTG in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggtggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgaccagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +21916 JY8QFUQ01BVFZU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1008 96.31 209/217 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [1.17.38.11] CSNGYGDFPRRW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +21917 JY8QFUQ01CZYWR productive Homsap IGHV3-9*01 F 888 89.55 197/220 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD3-22*01 F 2 8 8 26 8.8.26 [2.17.38.11] CVKDHGVTYFYDSVGYVSGAYNYAMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cgtctctggattcacctttgatgattttggcatgcactgggtccggcaagttccagggaagggcccggagtgggtcgcaggtattagttggaatggtggacatatggactatgcggactctgtgaagggccgattcaccgtgtcccgagacaacgccgagaattccctgtatctgcaaatgaacagtctgacacctgaagacacggccctgtattactgtgtaaaagaccatggcgtcacttacttttatgacagtgttggttatgtctccggggcgtacaactacgcaatggacgtctggggccaggggacgacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21918 JY8QFUQ01BRCPZ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 7 8 X 7.8.X [2.17.38.11] CARGHSYYVSSGPDY## out-of-frame - in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) agcctctggattcaccttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactgggggccacggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21919 JY8QFUQ01BYIH9 No results +21920 JY8QFUQ01BXAQC unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [2.17.38.11] CAFSRALTGEVDRLP*PL# out-of-frame - stop codons in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); gcctccggattcacctttagtagttactggatgcactgggtccgccaaactccagGgggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcctttagtagagcactcacgggggaagtggatcgactaccttgaccactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag +21921 JY8QFUQ01AC1K9 productive (see comment) Homsap IGHV3-48*01 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagGggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21922 JY8QFUQ01AV8QS unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 X 8.7.X [4.17.38.11] CARRGPHFMI (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagacggggtccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +21923 JY8QFUQ01CWHPI productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 91.63 197/215 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'GCGGGA' (6 nucleotides at position 92 to 97 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagTtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcaGCGGGAgtgggagcaccaactccaaccCcctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21924 JY8QFUQ01BGTAF No results +21925 JY8QFUQ01C1ORV productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +21926 JY8QFUQ01B023Y No results +21927 JY8QFUQ01CD1SU unproductive Homsap IGHV4-4*08 F, or Homsap IGHV4-59*01 F or Homsap IGHV4-59*07 F 782 85.12 183/215 nt Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD7-27*01 F 3 8 7 X 8.7.X [1.17.38.11] CASVRYLGERI#FDHW out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tctctggtggctccatgactggttactactggagttggatccggcagtccccagggaagggactggaatttgttggatctatctcttctgttggggacaccaactttgacccctccctcaggagtcgactcaccatgtccgtagacacgtccaagaaccagttttccctgaaagtgacctccgtgaccgcagcggacacggccgtctattactgtgcgagcgtgcgctatctcggcgaacgaatttttcgaccactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21928 JY8QFUQ01APW27 unproductive (see comment) Homsap IGHV1-18*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-19*01 F 1 8 8 11 8.8.11 [0.17.38.11] CARVG*IGWYAYW in-frame + stop codons in FR2-IMGT at codon 39 of V-REGION: 'T' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); tggttacacctttaacacctatggttTtcagttgggtgcgacaggcccctggagaagggcttgagtggatgggatggatcagcggtcacaatggtaacacaaagtatgcacagaagttccaggacagagtcaccctgaccacagacacatccacgagcacagccttcatggaattgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagtcgggtagattggctggtacgcctactggggccagggaaccctggtcaccgtcgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggctt +21929 JY8QFUQ01CKKV6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21930 JY8QFUQ01CGLTX productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 967 92.44 208/225 nt 92.0 207/225 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD1-26*01 F 3 8 10 14 8.10.14 [2.17.38.11] CTRDLSGSYSGAFDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); ggatctggattcacctttggtgactttgctatgagctggtttcgccaggctccagggaaggggctggagtggctaggtttcattagaagcaaaatttatggtgggacaccagaatacgccgcgtctgtgaaaggcagatgtcccatctcaagagatgattccAaaaaacatcgcctatctgcaaataaacggcctgaaaaccgaggacacagccatgtatttctgtaccagagatctcagtgggagctactccggtgcttttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcagatgggaacgtggtcatcgcctgcctcgtccaggctcttccccca +21931 JY8QFUQ01CA67J unknown (see comment) Homsap IGHV3-30*15 F 887 89.91 196/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctccggattcacctttagtaaatattccatgaactgggtccgccaggctccaggcaaggggctcgagtgggtggcacttatatcatacgatggaagtagaaaaatctacgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactacttttggactattgggggcccagggaaacccctgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21932 JY8QFUQ01BJL0D productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 820 86.3 189/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAKVGNLYFFEYW in-frame - gcctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21933 JY8QFUQ01A9AD7 unproductive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 930 92.99 199/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [0.17.38.11] CAKGSFDSSGRPEAFDI## out-of-frame + Other possibilities: Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggaggcaccttcagtagatatgctttcagctgggtgcgacaggcccctggacaagggcttgagtggatgggagggatcgtccctctctttggttccataaagtacgcacagaagtaccagggcagagccacgattaccgcggacgaatccacgagcacagtctacatggagctgagcagcctgagatctgacgacacggccatgtattactgtgcgaagggttcctttgatagtagtggtcgccctgaggcttttgatatctggggccaagggtacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +21934 JY8QFUQ01CF9AT No results +21935 JY8QFUQ01C812Q productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 849 87.0 194/223 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD4-23*01 ORF 3 8 10 14 8.10.14 [1.17.38.11] CSRRSTLVTGYVFDKW in-frame - Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggaatcaactttcgtgatcatgccatgagctggttccgccaggttccagggaaggggctggagtgggtaggtttcattagaagttctcaatacggtggagatacagaatacgccgcgtctgtggaaggcagattcaccatctcaagagacgattccaaaagcatcgcctatttggatatgaatagcctgaaaatcgacgacacagccctatattactgttcccggaggtcgacgttggtgactggatacgtctttgacaagtggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21936 JY8QFUQ01DCXVQ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 93.58 204/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSGGYTHNYFDYW in-frame - cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggcctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttntattactgtgcaaaaggggatagtggtggttatacccacaactactttgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21937 JY8QFUQ01AN0AS No results +21938 JY8QFUQ01ACWF5 unproductive (see comment) Homsap IGHV3-33*04 F (see comment) 327 62.44 128/205 nt 60.0 123/205 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 25 64.29 9/14 nt Homsap IGHD5-12*01 F 2 5 8 65 5.8.65 [X.17.38.8] CAKYLFRCLRLTLDRTWGPGEPVAPPSPHAIQAKAHRSSPLGTLLQEXLWGAQRPWAAWSKDYFPEP in-frame + stop codons Low V-REGION identity (62,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'GAGTAATAAATCACTAG' (17 nucleotides at position 98 to 114 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 77 of V-REGION: 'T' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'GT' (2 nucleotides at position 147 to 148 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'CAAGG' (5 nucleotides at position 164 to 168 in the user submitted sequence), (cause frameshift); cagcctctggattcaccttcagtgactatcacatgtactggGgtccgccaggctcagggcaggggctggagtgggctggcagttatatcatatgatgGAGTAATAAATCACTAGtgtagactccgtgaagggccgattcaTccatcGTccaggagacaagttcCAAGGatgcgctggcttttgctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaagtacctcttcaggtgtctacgacttactttggaccgtacctgggggccaggggaacccgtggctccaccgtctcctcacgccatccaggccaaggcccatcggtcttccccccttggcaccctcctccaagagcncctctggggggcacagcggccctgggctgcctggtcgaaggactacttccccgaaccggtggacggtgtcgtggcaactcg +21939 JY8QFUQ01BOBY3 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 9 7 12 9.7.12 [1.17.38.11] CAANLGHGSYFKYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 94 of V-REGION: 'T' (1 nucleotides at position 186 to 186 in the user submitted sequence), (cause frameshift); tctctggtgactccgtcagcagtgataactggtggagttgggtccgccagaccccagggaaggggctggagtggattggagaaatctatcatggtgggaccaccaactacaatccgtccctcaagggtcgagtcaccttatcggtcgacaagtccaagaaccaattctctctgagaatgacctctTtttaccgccgcagacacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21940 JY8QFUQ01B7KYD No results +21941 JY8QFUQ01BEUNL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21942 JY8QFUQ01AQKZO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21943 JY8QFUQ01B3VKV No results +21944 JY8QFUQ01AJUZ2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 890 90.7 195/215 nt Homsap IGHJ4*01 F 150 79.17 38/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [0.17.38.11] CAKDLVVTSIGPQGIHGH## out-of-frame - ctgggttcacctttagcagctatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaagtatcagttttagtggtgagagaacatattatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacagtacatttgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaagatctggtggtgactagtattggcccccagggaatccatggccactgggggccgaggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21945 JY8QFUQ01C7N4Z unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 3 10 9 X 10.9.X [1.17.38.11] CARGGDYYDSGGLDY## out-of-frame - tccggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtgattattatgatagtggtggtcttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21946 JY8QFUQ01BXEV0 unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 94.17 210/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 X 8.10.X [1.17.37.11] CTTGGWN*L##W out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 162 in the user submitted sequence), (cause frameshift) cctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacaggggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21947 JY8QFUQ01A2GYI unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 92.66 202/218 nt Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CARPFSGRWCFDL## out-of-frame + Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagttactcctggatgcactGgggtccgccaagttccagggaaAGggggccggtgtgggtctcacaaattaaaagtgatgGggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctgggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccaggggcttcttccccca +21948 JY8QFUQ01AVWB4 No results +21949 JY8QFUQ01DDC0C productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1009 95.89 210/219 nt 95.43 209/219 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRSEYSSSNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 139 to 139 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcaccCatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttccccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +21950 JY8QFUQ01BZKZW No results +21951 JY8QFUQ01CBSDR unproductive Homsap IGHV3-30*04 F, or Homsap IGHV3-30*14 F or Homsap IGHV3-30-3*03 F 1004 95.87 209/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKKGPNRITIFWSGHW#YYGMDVW out-of-frame + cctctggattcaccttcagtagctatgctatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatctgatggaagtaataaaaactatgcagactccgtgaagggccgattcaccatctccagagacaattccaacaacacactgtatctacacatgaacagcctgagagctgaggacacggctgtttattattgtgcgaagaaagggccaaaccgtatcacgattttttggagtggtcactgggtactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +21952 JY8QFUQ01B8FR6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1026 97.24 211/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 11 8.8.11 [1.17.38.11] CVVQILGATIDYW in-frame + ctctggattcaccttcaatacctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtggtagtacttacataaagtacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtggtccagatcctaggggctacgattgactactggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21953 JY8QFUQ01AGUNF unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21954 JY8QFUQ01C85VB unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD5-12*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDLFQVSTTYF*LLG in-frame - stop codons Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttacttttgactactgggggcccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggncttcccccctggcaccctcctcccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +21955 JY8QFUQ01C2FK7 unproductive (see comment) Homsap IGHV3-71*01 P 1106 99.55 223/224 nt 98.66 221/224 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD2-21*02 F 2 8 10 20 8.10.20 [1.17.38.11] CARIHPRLRGGGDCYYGWFDPW in-frame + stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgactactacatgagctgggtccgccaggctcccgggaaggGggctggagtgggtaggtttcatcagaaacaaagctaatggtgggacaacagaatagaccacgtctgtgaaaggcagattcacaatctcaagagatgattccaaaaTgcatcacctatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgaggatccatccccgcctacgtggcggtggtgactgctattatgggtggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaaactca +21956 JY8QFUQ01B1VYC No results +21957 JY8QFUQ01CMVKV productive (see comment) Homsap IGHV3-48*03 F 855 88.48 192/217 nt 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaGggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagGactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21958 JY8QFUQ01AUPY6 No results +21959 JY8QFUQ01DJI2W productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 908 91.2 197/216 nt 89.81 194/216 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [2.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcttctgggttcaccgtcagtagcaagGttcatgagctCgggtccgccaggctccagggaaTggggctggantgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +21960 JY8QFUQ01B6U5G No results +21961 JY8QFUQ01CCWTD No results +21962 JY8QFUQ01AZUTN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD3-9*01 F 2 8 8 18 8.8.18 [1.17.38.11] CVKVAGDYRTPNYGWHFDLW in-frame - ctctggattcacctttagcacctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggtagtggtggcagcacattctactcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactggatctgcaaatgaatagcctgagaggcgaagacacggccgcatattactgtgtgaaagtggccggtgactatagaactcccaactacggctggcacttcgatctctggggccgaggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21963 JY8QFUQ01B9C15 unproductive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 918 91.71 199/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*02 F 1 8 8 X 8.8.X [1.16.38.11] CVRAGFGGVIG#FDCW out-of-frame - stop codons in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 203 to 203 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift) cctctggattcacctttggttattatggcatgactgggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacgGgccttatatcactgtgtgagagcagggttcgggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21964 JY8QFUQ01B45A8 unproductive Homsap IGHV3-7*01 F 949 93.52 202/216 nt 92.59 200/216 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDPRSVSRYSLFGLL# out-of-frame + in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 212 to 212 in the user submitted sequence), (cause frameshift); tctggattcacctttagtgactattggatgagctgggtccgccaggctccagGggaaggggctagagtgggtggccaacataaatagagatggaagtgagcaacactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacatggctatgtatTttttgtgcgagagatcctcgttccgtgagcaggtactctttatttggactcctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct +21965 JY8QFUQ01CEGTD productive Homsap IGHV4-61*02 F 970 93.24 207/222 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [2.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + gtctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21966 JY8QFUQ01DWHZD No results +21967 JY8QFUQ01DUQPR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVKDISRSGCFEYW in-frame - tctggattccagtttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +21968 JY8QFUQ01BDGHR productive (see comment) Homsap IGHV4-39*03 F 929 91.36 201/220 nt 90.45 199/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'A' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaacagtagAaaattattattggggctggatccgccagcCccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +21969 JY8QFUQ01AZW95 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAIEHTLPSGQGLGIEYFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'AC' (2 nucleotides at position 158 to 159 in the user submitted sequence), (cause frameshift); ctctggattcaactttaacagctttgccatgagctgggtccgccaggttccagggatggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactccgtgAaagggccggttcaccatctccagagacaactccaaACaaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgatcgagcatacccttccgtccggacagggattagggattgaatatttctggggccagggaaccctggtcatcgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +21970 JY8QFUQ01DHB91 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 833 87.16 190/218 nt 86.7 189/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRGTREWSGIDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcattttcagtaactactggatgcactgggtccgccaagctccagggaaggGggctgctctgggtctcagtcattaatagtgacggcagtgaaattcactacgcggactccgtgaggggccgattcaccatctcccgagacaacgccaagaacacgctgtatttgcaaatggacaatctcagaggcgacgacacggctctatattattgtgtaagagggacaagggaatggagcgggattgactactggggtcagggaaccctggtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatcgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21971 JY8QFUQ01B35E5 unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F (see comment) 739 82.19 180/219 nt 79.91 175/219 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD5-12*01 F 2 8 8 X 8.8.X [2.16.38.11] CV*KDVDTMTTASTT## out-of-frame - stop codons Low V-REGION identity (82,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'T' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 97 of V-REGION: 'TC' (2 nucleotides at position 199 to 200 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) agcgtctggattctccttcaTgcaattatgccgatcactgggtccgccagctccaggcaaggggctggagtAgggtggcggAccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggataccctttcgggtTCgacgacacggctgtctattattgtgtttaaaaggacgtggatacaatgactacggcctcgactactgggggccccgggaaccctgctcaccgtctcctcagcctcccaccaaggggcccatcggtcttcccccctggcncccctccctccaagagcacctctggggggnacagcggccctgggntgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactag +21972 JY8QFUQ01DRVYG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggctttttccccca +21973 JY8QFUQ01A7IC1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.99 194/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDGVRGVGAYYIYYFDLW in-frame + cctctggattcacctttggcctctatgccatgaactgggtccgccaaactccagggaaggggctggagtggctcgcaactattagtggtagtggaagtagatcattttacgcagactccctgaagggccggttcaccatctccagagacaattccaagggcacggtatacctggaaatgaccaccctgagagccgaggacacggccgtatattactgtgcgagagatggggtccgtggcgttggtgcttactacatctactattttgacttatggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21974 JY8QFUQ01AECMS productive Homsap IGHV3-66*02 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame - ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +21975 JY8QFUQ01BU3KK unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*02 F or Homsap IGHV3-13*05 F or Homsap IGHV3-30*05 F or Homsap IGHV3-30*13 F 108 53.33 72/135 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found ctctggattcaacctcaatacctttggcatgaactgggtccgccctgctccaggagcaccctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaact +21976 JY8QFUQ01DPHLJ No results +21977 JY8QFUQ01A152Y unproductive Homsap IGHV3-48*01 F 1080 99.54 216/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CASNFLEWFPWG#YYYGMDVW out-of-frame - ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgaattttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21978 JY8QFUQ01BI65O unproductive Homsap IGHV4-61*02 F 786 99.38 159/160 nt 98.75 158/160 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-8*01 F 3 X 7 X X.7.X [X.8.38.11] CARGYCSNAVCYQIMN## out-of-frame - in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) ggaagggactggagtgattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagccaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggccgtgtattactgtgcgagaggatattgttctaatgctgtatgctatcaaatcatgaactgggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21979 JY8QFUQ01B957P productive (see comment) Homsap IGHV1-18*01 F 804 88.29 181/205 nt 87.32 179/205 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD1-20*01 F 1 5 8 11 5.8.11 [X.17.38.11] CARVIRTNWLDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tggttacacctatggcgtcacctgGggtgcgacaggCcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatgataatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacggccgtatattattgtgcgcgagtaattcgaaccaactggctcgacccctggggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21980 JY8QFUQ01C1FLO productive (see comment) Homsap IGHV1-3*01 F 957 94.39 202/214 nt 93.93 201/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARWNNDLDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); tggatacaccttcagtacctatactataaaCttgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccccgaagatgggaacgtggtcgtcgccatgcctggctccagggcttcttcccccca +21981 JY8QFUQ01BK8O3 productive (see comment) Homsap IGHV3-30*10 F (see comment) 752 83.03 181/218 nt 82.57 180/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaagggccgattctccatctccagagacaattccaaaaaGtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +21982 JY8QFUQ01A886F unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 125 56.52 65/115 nt 8 10 X 8.10.X [1.17.2.X] null + No rearrangement found ctctggattcagctttagttactattggatgagctgggtccgccaggctcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21983 JY8QFUQ01CEADI unproductive Homsap IGHV3-33*05 F (see comment) 752 83.03 181/218 nt 82.11 179/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CVKGRGYNDYGLDY## out-of-frame - Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatAttaatgaaaagatattatgcagagtccgtgagGgggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactgggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +21984 JY8QFUQ01B1GGR No results +21985 JY8QFUQ01ASULW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 877 89.81 194/216 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame - tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccctccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21986 JY8QFUQ01BA8HI unproductive Homsap IGHV3-48*02 F 895 90.74 196/216 nt 88.89 192/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CARGQKMATKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'AG' (2 nucleotides at position 35 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'T' (1 nucleotides at position 209 to 209 in the user submitted sequence), (cause frameshift); tctggattcaccttcgacagatacagtatgaactAGgggtccgccaggctccagggaggggactggagtgggAtttcatacataagtactactactagtaacagatactacgcagCacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctTgtatattattgtgcgagaggtcaaaaaatggctacaaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctggggctgcctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21987 JY8QFUQ01A1WNI unproductive Homsap IGHV3-30*10 F (see comment) 725 81.65 178/218 nt 81.19 177/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [2.17.37.11] CLAEVGGRQFDN## out-of-frame - Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 124 in the user submitted sequence), (cause frameshift) acctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggcgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactgggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatggggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +21988 JY8QFUQ01CFYEV unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 723 82.24 176/214 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD2-15*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDWGGSFDRYYFDY## out-of-frame - Low V-REGION identity (82,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactgggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +21989 JY8QFUQ01DJU2K productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 800 86.05 185/215 nt 84.65 182/215 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CATVRHLGERIFDFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); tctctgggggcCaccatgagtagtttctactggagctgggttcggcagTcccccagggaggggactggagtggattggatttgtttcttacagtgGggcccaccaactacagcccctccctcaagagtcgagtcaacttatcactggacgcggccaacaaacagttctctttgcagctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtccccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgccctggtccagggcttcttcccccc +21990 JY8QFUQ01CCN49 productive (see comment) Homsap IGHV3-23*03 F (see comment) 855 88.48 192/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 12 8.7.12 [2.17.38.11] CARQTAPFGYFEDW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CCN49 ; 8 AA in Homsap_IGHV3-23*03) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); aggctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggaaGggggctggagtgggtctcagttatttatagcggtggtagtgcatattatgcagactccgtgaGggggccgattcaccatcgccagagacaaatctaagaacgtgttgtatcttcaaatgaacagtctgagacctgaggacacggctgtgtactactgtgcgagacagactgccccttttgggtactttgaggactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +21991 JY8QFUQ01A0SY0 No results +21992 JY8QFUQ01CCZV6 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 957 94.39 202/214 nt 93.93 201/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD1-26*01 F 1 8 7 18 8.7.18 [1.17.38.11] CARGWAQQAGATFVGWFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctatggtgggtccttcagtggttacacctggaactggatccgccagcCccccagggaaggggctggagtggattggggaaatcaatcatagtggcaggaccaactacaacccgtccctcaagagtcgagtcaccatatcaatagacacgaccaacaaccagttctccctgaagttgacctctgtgaccgccgcggacacggctgtatatttctgtgcgagaggttgggcccaacaagcgggagctacgtttgttggctggttcgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +21993 JY8QFUQ01AJQBH No results +21994 JY8QFUQ01A8NO3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccagttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21995 JY8QFUQ01DNXJJ unproductive (see comment) Homsap IGHV3-66*02 F 953 93.95 202/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 X 8.7.X [1.17.38.11] CVGRSSKG*LFR#YW out-of-frame + stop codons cctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtggggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +21996 JY8QFUQ01APYLJ productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataGccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +21997 JY8QFUQ01A20SX No results +21998 JY8QFUQ01A2ZKE productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgaaagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggctgtcgtggaact +21999 JY8QFUQ01BZ3QS productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [2.16.38.11] CARKGLVPSMFFFDFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gtctctggtGgggtccttcagtggttacttctggaactggatccgccagcccccagggaagggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtgctcctcagcctccacaaggccatcggtcttgccccctggcaccctctccaagagcacctctgggggcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22000 JY8QFUQ01CCTZY productive Homsap IGHV3-7*01 F 887 89.91 196/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + cctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22001 JY8QFUQ01AJU3I unproductive Homsap IGHV4-30-2*02 F 308 95.59 65/68 nt Homsap IGHJ3*02 F (see comment) 133 74.0 37/50 nt Homsap IGHD3-22*01 F 3 X X X X.X.X [X.X.22.11] CARLKLSNGYYFDY## out-of-frame - Other possibilities: Homsap_IGHJ5*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) ggtccaagagccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattattgtgcgagattgaaattatctaatggttactactttgactactgggggccaaggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +22002 JY8QFUQ01B24EY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); cctctggattcacctttaccGaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgCaggggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22003 JY8QFUQ01AZ15O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + cctctggattcaccctcaggacctatagcgtgaactgggtccgccaggctccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22004 JY8QFUQ01A18LF unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 955 93.15 204/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [2.17.38.11] CARDRRGYSYEMDY## out-of-frame + acctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22005 JY8QFUQ01CQ1Y4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22006 JY8QFUQ01AXNWU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [2.17.38.11] CAKDKWYYDSSGYQYYLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); gcctctggattcCccctttagcaactGatgacatgaAattgggtccgccaggctccagggaaggggctggagtgggtctccggtattagtggtagtggcggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctggatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagacaaatggtactatgatagtagtggttatcaatactaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22007 JY8QFUQ01B1VT1 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 93.72 209/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'A' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaAaaaaatatgctgtatctAgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +22008 JY8QFUQ01A0AX9 No results +22009 JY8QFUQ01CJNT4 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22010 JY8QFUQ01B3A8Z productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 143 to 143 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccCagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22011 JY8QFUQ01CSWJJ productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 768 82.96 185/223 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 13 8.10.13 [1.17.38.11] CATDSPTGYYAFDVW in-frame + Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctgggttcgttttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22012 JY8QFUQ01CB27C productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggaggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22013 JY8QFUQ01AUJPZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +22014 JY8QFUQ01CGB39 unproductive (see comment) Homsap IGHV3-30*17 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAGRFNWGSVLL*Q*WFK#YW out-of-frame - stop codons in FR2-IMGT at codon 46 of V-REGION: 'A' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctctagattcaccttcagtagctataatatgcactgggtccgccaggctccAgggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcggggagatttaactggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22015 JY8QFUQ01BHGAO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 974 93.67 207/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - ggcctcctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22016 JY8QFUQ01B6CFI productive (see comment) Homsap IGHV3-9*01 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDRKGSNWYYFENW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); ctctggattcaggtttgatgattatgccatgcactgggtccggcaagcGtccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +22017 JY8QFUQ01C06AD No results +22018 JY8QFUQ01BNCIH unknown (see comment) Homsap IGHV1-2*02 F 822 87.38 187/214 nt 86.92 186/214 nt 8 8 X 8.8.X [0.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 37 of V-REGION: 'A' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); tggatacatattcaccgacAttttatatacactgggtacgacaggcccctggacaagggcttgagtggatgggatccatcaatcccaacagtggtgtcacaacctacgaagagaagtttcggggcagggtcaccatgaccagggacacgtccatcactacagcctacatggaactgacaagccttacatcagacgacacggccgtatattactgtgcgaaacatcctcttcgatcaacaagtggacattcctacttagattcctgggggccagggaacccctggtcacagtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +22019 JY8QFUQ01C0BEM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 571 88.89 128/144 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 X 8 16 X.8.16 [X.2.38.11] CAKEQRGSGWSRSALDVW in-frame - tcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcgtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22020 JY8QFUQ01CI1Z5 No results +22021 JY8QFUQ01A5TCV productive Homsap IGHV3-48*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + ctctggattcgccttcagtagttccagcatgaactgggtccgccagggtccagggaaggggctggagtggatttcacacattaggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +22022 JY8QFUQ01A6ZD5 productive (see comment) Homsap IGHV3-7*01 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 7 8 11 7.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) gctctggattcagcttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +22023 JY8QFUQ01B1LIV productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1040 97.71 213/218 nt Homsap IGHJ3*02 F 88 64.0 32/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame + cgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +22024 JY8QFUQ01C5ZII unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [1.17.38.11] CASFRILESGY## out-of-frame + tctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtatcctggaaagtggctactgggggccagggaaccttggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22025 JY8QFUQ01C7H7S unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P 98 52.63 70/133 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons tcctgattcatcttcagtgactactacatgacctggatccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22026 JY8QFUQ01CXEH2 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt 88.94 193/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKNRGVGDG##WYFDFW out-of-frame - stop codons in CDR2-IMGT at codon 57 of V-REGION: 'CTA' (3 nucleotides at position 84 to 86 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'G' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); ctctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattaCTAatggtggtggtggtgtcgtactctacgcagactccgtgaAagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttaGtttctgtgcgaaaaataggggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22027 JY8QFUQ01AEWVB productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARELGGSGTCGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccaggcactatatgcactgggtgcgacaggCcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggggcagagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +22028 JY8QFUQ01APIZE unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-30*01 F 106 95.65 22/23 nt 6 X X 6.X.X [1.X.X.X] null + No rearrangement found cctctggattcactttcagtagc +22029 JY8QFUQ01BOAH5 unproductive Homsap IGHV3-9*01 F (see comment) 771 83.64 184/220 nt 81.82 180/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 1 8 8 X 8.8.X [2.17.38.11] CVKGHGRGVRDSCH#FDHW out-of-frame + Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'GC' (2 nucleotides at position 133 to 134 in the user submitted sequence), (cause frameshift); agcctctggattcGactttaagggaatatgccatacactgggtccggcaagttccaggaaaggggcCtggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatGggggactctgtgaggggGCccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaaggacatggtcgcggggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctcctaccaaggggcccctatcggtcttcccccctggcaccctcctccaagcagcacctctggggggccacagcggccctggggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc +22030 JY8QFUQ01CZX40 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGG## out-of-frame + cctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtggggggggaccagggagccctggtctccgtctcctcagcatcccccgaccaggcccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc +22031 JY8QFUQ01ARUGW unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1019 95.93 212/221 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 10 7 X 10.7.X [1.17.38.11] CAWGVVRVELL*LL# out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcagcagtactagttactactggggctggatccgccagcccccagggaaggggctggagtggattggtaacattcattctagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcatggggggtggttcgggttgaactactttgactactgggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +22032 JY8QFUQ01BS3SW productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 811 85.84 188/219 nt 85.39 187/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 1 8 8 11 8.8.11 [2.17.38.11] CARDGEWEMLDHW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'GA' (2 nucleotides at position 85 to 86 in the user submitted sequence), (cause frameshift); gcctccggattcaccttcagtaggtattggatgtattgggtccgccaagctccaggcaaaggggctgtgtgggtctcacgcattGAaaaagtgatgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacatatttttgtgcaagagacggggagtgggagatgcttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22033 JY8QFUQ01DKMNN productive (see comment) Homsap IGHV3-7*01 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 77 of V-REGION: 'A' (1 nucleotides at position 134 to 134 in the user submitted sequence), (cause frameshift); ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcAaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22034 JY8QFUQ01DKSY4 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22035 JY8QFUQ01CK2OL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22036 JY8QFUQ01CGLGT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 883 89.5 196/219 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ggctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggcgccctgaccagcggcgtgc +22037 JY8QFUQ01A3DME productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.49 197/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagGggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22038 JY8QFUQ01CGBK8 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 388 63.93 140/219 nt 8 8 X 8.8.X [2.17.38.X] null + No rearrangement found Low V-REGION identity (63,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22039 JY8QFUQ01BKFT5 No results +22040 JY8QFUQ01DLZC6 No results +22041 JY8QFUQ01A03E3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); tcaggattcaccttcagtaggtactggaGtgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgtctggtccagggcttcttccccca +22042 JY8QFUQ01AI9LC productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-7*01 F 3 8 8 13 8.8.13 [1.17.38.11] CATGAGNWNYIFNYW in-frame + ctctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtggtttttatatatactacgcggactcagtgaagggccgagtcaccatctccagagacaacgccaagaactcgctatttctgcaaatgaacaacctgcgagccgaggacacggctgtctattactgtgcgacaggggccggaaactggaattacatttttaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22043 JY8QFUQ01CCMPT No results +22044 JY8QFUQ01AQ6H1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*02 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDRYPRSTAITAPDYW in-frame - cctctggattcccctttagcaactatgccatgacctgggtccgccaggctccaggggagggactggaatgggtctcaagtattagaggtagtggtgacaggacatcctacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagctgaacaacctgagagccgaggacagggccgaatattactgtgcgaaagatcgctaccctcggtcgacagctattacagcgcctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22045 JY8QFUQ01ASSCH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CITSFGGRSLAYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 68 of V-REGION: 'GGAAA' (5 nucleotides at position 112 to 116 in the user submitted sequence), (cause frameshift); ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcGGAAAaaactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +22046 JY8QFUQ01DWXM5 No results +22047 JY8QFUQ01BEES7 productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1035 95.58 216/226 nt 95.13 215/226 nt Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD3-10*02 F 1 10 9 13 10.9.13 [1.17.38.11] CTREGTLLRTVWTSG in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 152 to 152 in the user submitted sequence), (cause frameshift); tccgggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacCccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggccgtctattactgtacgagagaggggaccctactacgtacggtatggacgtctggggccaaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +22048 JY8QFUQ01B1HK3 No results +22049 JY8QFUQ01AK9IE unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 679 91.36 148/162 nt 90.74 147/162 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-18*01 F 1 X 7 X X.7.X [X.9.38.11] CARSKSGYSYGDFLH## out-of-frame - in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gggagggggctggagtggattgggagcatctattatagtgggagcatctcttacaaccCcgtccctcaggagtcgaatcaccatgtccgtggacatgtccaagaaccagttctccctgaggctgagctctgtgaccgccgcagacacggctatttatttctgtgcgcggtccaagagtggatacagctatggtgacttcttacactgggggccagggaaccctggtcaccgtctccctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +22050 JY8QFUQ01BT201 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 851 88.07 192/218 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CIMDLVGRADY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattgggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22051 JY8QFUQ01C54J3 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1019 95.93 212/221 nt 93.21 206/221 nt Homsap IGHJ3*02 F (see comment) 124 72.0 36/50 nt Homsap IGHD4-11*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CARLDYTRYFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'GG' (2 nucleotides at position 38 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'CA' (2 nucleotides at position 62 to 63 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'GC' (2 nucleotides at position 74 to 75 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 92 of V-REGION: 'C' (1 nucleotides at position 191 to 191 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagTttactactGGggggctggatccgccagcccccCAggggaaggggGCtgggagtggattgGggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgCacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +22052 JY8QFUQ01AMTG3 productive (see comment) Homsap IGHV3-48*02 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDRGGSAYPIFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); cctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggAttttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +22053 JY8QFUQ01DL2G9 unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 814 86.57 187/216 nt 84.72 183/216 nt Homsap IGHJ1*01 F (see comment) 188 84.62 44/52 nt Homsap IGHD6-19*01 F 2 8 7 X 8.7.X [2.17.38.11] CVGSRSGIFSL#FQYW out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'ATG' (3 nucleotides at position 61 to 63 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 171 to 171 in the user submitted sequence), (cause frameshift); gcctctggattcactgtcaataacaactacatGgggttgggtccgccaggctccaggggaATGggggctggagtgggtctcGactactttattacggtggcaccacatattacgcagactccgcgaagggccgattcaccatctccagagacacctccaggaacacacttTtttcttcagatgaacagcctgagaagcgacgacacggctctatattattgtgttgggagtcggagtgggatcttcagtctccttccaatactggggccagggcacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22054 JY8QFUQ01CGEBO No results +22055 JY8QFUQ01BQT5H No results +22056 JY8QFUQ01CE87O productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 955 93.15 204/219 nt 92.24 202/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [2.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); gcctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaGggggctggagtGgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagga +22057 JY8QFUQ01B71RD unproductive Homsap IGHV3-7*01 F 841 87.56 190/217 nt 86.64 188/217 nt Homsap IGHJ1*01 F 134 73.08 38/52 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDRPGGWALDY## out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'TG' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); ctctggattcagttttagtgacttttggatgcactgggtccgccaggcnccagggaaTGggggctggagtgggtggGcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactgggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22058 JY8QFUQ01DWWKT No results +22059 JY8QFUQ01DW0DI productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +22060 JY8QFUQ01A5LEP No results +22061 JY8QFUQ01AX7FM No results +22062 JY8QFUQ01DI2O4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [2.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgCaggggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccaggggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22063 JY8QFUQ01DQPV4 No results +22064 JY8QFUQ01AMIZK productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'CCCAAT' (6 nucleotides at position 84 to 89 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcaacCCCAATcctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +22065 JY8QFUQ01AHWBC No results +22066 JY8QFUQ01AGP4K productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt 84.33 183/217 nt Homsap IGHJ1*01 F 143 75.0 39/52 nt Homsap IGHD6-13*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARPDGGNGWSFKNTSQMW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'GGG' (3 nucleotides at position 60 to 62 in the user submitted sequence), (do not cause frameshift); ctctggattctcctttaatagttatgGgcatgagttggttccgccaggctccgggggaaGGGgggctggagtgggtctcatctattaccggcatgggtaatgacgcatactacgcagactccgtgcagggccggttcaccgtctccagagacaatcccgggaacaccctgtttctgcgaatggacagcctgagaatcgaggacacggccgtatattactgtgcgagacctgacggaggcaacggctggtcctttaaaaatacttcccagatgtggggccagggcacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +22067 JY8QFUQ01B0UCM unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 401 77.21 105/136 nt 76.47 104/136 nt 8 6 X 8.6.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (77,21% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) cctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22068 JY8QFUQ01AMTHS productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccctgaaccggtgacggtgtcgtggaactca +22069 JY8QFUQ01CLXP0 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 957 92.38 206/223 nt 90.58 202/223 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 2 10 7 13 10.7.13 [2.17.38.11] CARRGSYGSGSYYPW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'T' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); tgtctctggtggcgccatcagcagtaatAgtttactactgggactggatccgccagcccccagggaagGgggctggagtggattgggagtatGtttttatactgggggTcaccttctacaacccgtccctcaagagtcgagttaacatttccgtggacacgtccaagagccagttctccctgaggctgagctctgtgaccgccgcagacacggctgtgtatcactgtgcgagacgtggttcctatggttcggggagttattatccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgttgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22070 JY8QFUQ01C633P productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 913 91.67 198/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 21 8.8.21 [1.17.38.11] CVRVGAPYYDFWSGYQTNWFDPW in-frame - tctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgcaagtactacttccatacattatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggcgccatattacgatttctggagtggctatcagactaactggttcgacccctggggccagggaactctggtcaccgttacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22071 JY8QFUQ01BUVZ9 No results +22072 JY8QFUQ01B0I72 productive (see comment) Homsap IGHV4-61*02 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 10 7 25 10.7.25 [1.16.38.11] CAREYPSDRDSSDSSGYLPTSGPLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) ctctggtggctccatcagcagaggtaattactactggacgtggatccggcagccgccgggacgggactggagtggattggcgtatctatcccagtgggagaaccaactacagcccctccctcaagagtcgcgtcaccatatcagcagacacgtccaagaaccagttctccctgaagttgacctctgtgaccgccgcagacacggccttgtattactgtgcgagagagtacccctcggacagagattcctctgatagtagtggttatcttcccacctccgggccccttgactactggggcctgggaatccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22073 JY8QFUQ01AEWGV unknown (see comment) Homsap IGHV3-74*03 F 104 52.94 72/136 nt 8 7 X 8.7.X [2.17.11.X] null + No rearrangement found stop codons gcctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22074 JY8QFUQ01BL6G3 No results +22075 JY8QFUQ01AV7PZ unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 833 87.16 190/218 nt 86.7 189/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 124 72.0 36/50 nt Homsap IGHD1-1*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDHIWAFDF## out-of-frame + in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcagactctgtgaagggccgaatcaccatctccagagacaatgccaagaactcacttTtttctgcaaatgaacaccctgagagacgacgacacggctgtgtattactgtgcgagagaccacatttgggcttttgatttctgggggccaagggacaaaggttaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22076 JY8QFUQ01ADKWZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccggaaccaggtgacgggtgtcgtggaactc +22077 JY8QFUQ01BXQYJ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 937 92.24 202/219 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAREVIPTATYGMDLW in-frame - Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) gcgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac +22078 JY8QFUQ01BWXXP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 783 84.79 184/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [1.17.38.11] CTKTRVVLGITFPFYIYGLDVW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacgttcgacaactatgccatgagctgggtccgccaggcaccaggaaaggggctggagtgggtctccagtattagtggtaatggagaaattgtacaccacgcagacgccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtttttgcaaatgaatggagtgagagacgacgacacggccatttactactgtacgaaaacacgcgttgtgttgggaattacatttccgttctatatctatggtctggacgtctggggccaagggaccacggtcaacgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc +22079 JY8QFUQ01BY7OJ productive Homsap IGHV4-39*02 F (see comment) 772 83.33 185/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 10 7 22 10.7.22 [2.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame - Low V-REGION identity (83,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22080 JY8QFUQ01C12ZU unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 942 92.27 203/220 nt 91.82 202/220 nt Homsap IGHJ4*03 F (see comment) 123 72.92 35/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [2.17.38.11] CARDQSLGDARGF*HL# out-of-frame - stop codons Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagGggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctgggggatgcccgaggcttttgacatctgggggccaagggacaatggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22081 JY8QFUQ01B7K8E productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 928 91.78 201/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'TCA' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); gcctccggattcacctTttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctTCAcgggactaaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacacgcacccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22082 JY8QFUQ01B753F productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcacctttagtggctattggatgagttgggtccgccaggctccggggaagggtctggagtgggtggccaacatagagaaagatggaagtgacataaagtatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaaacgtggtcgtcgcatgcctggtccagggcttcttcccccc +22083 JY8QFUQ01BJ4C7 No results +22084 JY8QFUQ01AW1OG No results +22085 JY8QFUQ01CXATF productive Homsap IGHV3-48*03 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARESWWSGFYGWYDPW in-frame + cctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactca +22086 JY8QFUQ01B0C8G unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD1-20*01 F 3 8 8 X 8.8.X [1.17.38.11] CANASPRITGTYFYYYGMDV# out-of-frame + Other possibilities: Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctgggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaaactca +22087 JY8QFUQ01DM1XR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 915 90.91 200/220 nt 90.0 198/220 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-16*02 F 1 8 8 16 8.8.16 [2.17.38.11] CAKDPQQLLEDINWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 86 of V-REGION: 'AT' (2 nucleotides at position 166 to 167 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 93 of V-REGION: 'G' (1 nucleotides at position 188 to 188 in the user submitted sequence), (cause frameshift); agcctctggattcacctttcgcagctatgccatgagctgggtccgccaggctccaggaagggggctagagtgggtctcatctatcagtggtagtggtgataaaacaaagtacgcagactccgtgaagggccggttcaccatctccagagacaacgccaggaacacATtttttatctgcaaatggacaGgcctcagagccgaggacacggccgtctattactgtgcgaaagatcctcagcagttattggaagacataaactggttcgacccctggggccagggcacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22088 JY8QFUQ01BPG47 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22089 JY8QFUQ01CJ2DS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [2.17.38.11] CARDRLTISALDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggGggcttgagtgggtctcagctatagctgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22090 JY8QFUQ01B8VG4 productive Homsap IGHV3-72*01 F 993 94.17 210/223 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*01 F 3 8 10 15 8.10.15 [1.17.38.11] CSRVGGWVGRADGFDLW in-frame + ctctggactcaccttcagtgcccagtacttagactgggtccgccaggctccagggaagggactggagtgggttggccgtattagaagcaaaactaacagttacaccacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattctacgaactcactgtatctgcaaatgaacagcctgaaaaccgaagacacggccgtgtactactgttctagagtcggcgggtgggtggggcgtgctgatggttttgatctgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +22091 JY8QFUQ01CDXA6 unproductive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt 96.89 218/225 nt Homsap IGHJ6*01 F 90 60.32 38/63 nt Homsap IGHD1-26*01 F 3 10 9 X 10.9.X [1.17.38.11] CTRGSSRGGEI**ELL*##DFW out-of-frame - stop codons in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'AC' (2 nucleotides at position 151 to 152 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgGagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaaACcccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcgggggggagatatgatgagaactactatgagctggacttctgggggccagggaagcccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +22092 JY8QFUQ01C2553 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGRATGLVDWFDPW in-frame - ctctggattcaccttcaccaactacgccatgacctgggtccgccaggctccagggaaggggctggagtggatctcgactgttgtgggtggcggtggtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattcccagaacacgctgtatttgcaaatgtacaatttgggagccgaggacacggccctatattactgtgcgagaggtagagcgactggtctggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22093 JY8QFUQ01C8FJA No results +22094 JY8QFUQ01AFSLP unproductive Homsap IGHV3-11*01 F 1018 96.35 211/219 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [2.17.38.11] CAVDCTSISCNGD## out-of-frame - gcctctgggttcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggctttcatatattagtagtgctggtagtaccatatactacgcagactctgtgaggggccgattcaccatctccagggacaacaccaagaactcactgtatctgcaaatgaacagcctgagggccgaggacacggccgtgtattactgtgcggtagattgtactagtatcagctgcaacggagactggggccaggggaaccctggtcaccgtctcctcggcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22095 JY8QFUQ01CGR44 productive (see comment) Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt 81.57 177/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); ctctggattcaccGttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22096 JY8QFUQ01BR48U productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 847 87.67 192/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [2.17.38.11] CIMDLVGRADYW in-frame + ccctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatcccccgaccgagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22097 JY8QFUQ01CWZ6M productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 832 87.5 189/216 nt 86.57 187/216 nt Homsap IGHJ1*01 F (see comment) 188 84.62 44/52 nt Homsap IGHD3-10*01 F 2 8 7 15 8.7.15 [2.17.38.11] CARDGDFGSYQEFFQYW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CWZ6M ; 8 AA in Homsap_IGHV3-21*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); gcctcgggatttagGattcagtgactacagcctgagctgggtccgccaggctccagggaaggggccggagtgggtcgcaAttcattagtcgtaacagtcacataagctacgcggactcagtgaggggccgattcaccatcgccatggacaactccaagaactcactgcttctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagatggtgattttgggagctaccaggagttcttccaatactggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22098 JY8QFUQ01C2DKL productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [1.17.38.11] CSNGYGDFPRRW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22099 JY8QFUQ01BZL66 unproductive Homsap IGHV3-15*04 F 917 90.18 202/224 nt 88.84 199/224 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD6-25*01 F 3 8 10 X 8.10.X [1.17.38.11] CITGRTPSAWGY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 183 to 183 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'GA' (2 nucleotides at position 197 to 198 in the user submitted sequence), (cause frameshift); cctctggattcactttcagtaacgcctggatgtactgggtccgccaggctccagggaaggggctggagtgcgttgggcgtattggacgcagagttgatgacgggacaatagactacgctgcacccgtgaaaggcagattcatcatgtcaagagatgattcaAaaaaatatgttgtatctgcaAaatgaacagcctgGAaaaatcgaagacacggccatgtattattgtatcacaggtcgtacaccgtcggcttggggatacggggggccagggaaccatggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +22100 JY8QFUQ01C0J5I productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +22101 JY8QFUQ01BPG6V unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CAREKGSGPPHRHGRL# out-of-frame - Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcggggcccccccacaggcatggacgtctgggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22102 JY8QFUQ01CE6W2 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 7 8 10 7.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) ctctggattcagcttaagttctatggcatgaactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22103 JY8QFUQ01BERNX productive Homsap IGHV1-2*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [0.17.38.11] CARGGTVTAGGPRIVFGYW in-frame - tggctacaccttcaccgactactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcaaccctgacggtggtagcacaaagtatgcacagaaatttcagggcagggtcgccgtgaccagggacacgtcaattagcacagcctacattgaggtgaccagactgacatctgacgacacggccgtgtattattgtgccagaggagggactgtgacagcaggtggtcctcgtattgtctttgggtactggggccagggaacgttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22104 JY8QFUQ01BAB5T productive (see comment) Homsap IGHV3-72*01 F 1043 96.43 216/224 nt 95.98 215/224 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-11*01 ORF 2 8 10 13 8.10.13 [1.17.38.11] CVRGLHSNYYGMDVR in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgaccactacatggactGgggtccgccaggctccagggaaggggctggagtgggttggccgtagtagagacaaagttaacagttacagcacagaatacgccgcgtctgcgaagggcagattcaccatctcaagagatgaatcaaagaactcactgtatctgcaaatgaacagcctgaaaagcgaggacacggccgtgtattactgtgttagaggcctacacagtaattactacggtatggacgtcaggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22105 JY8QFUQ01B1PG0 No results +22106 JY8QFUQ01CFH88 unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CARAPESGSYPAEYFQH## out-of-frame - Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) gactggattcaccttcagtaactataccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatctggtttgatggaagaaatcaatactatgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagaggcgaagacacggctgtatattactgtgcgagagcccccgagagtgggagctacccggctgaatacttccaacactgggggccagggcaccccagtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctcccaagagcacctctggggggcacagcggccctggggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +22107 JY8QFUQ01BNGCY productive (see comment) Homsap IGHV4-61*02 F 829 86.76 190/219 nt 86.3 189/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 10 7 15 10.7.15 [1.16.38.11] CARDTGQTYGRGPLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 2 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) tctctggtgcctccataaataggggtaattattactggaactggatccggcagcccgccgggaaggctggaatggattggccgaatctatacaagtgggagcaccatctacaacccctccctcgggggtcgagtcaccatgactgtagacccgtccgagaatcagttcttcctgagactgagttctgtgaccgccgcagacacggccgtttatttttgtgcgagagacactggacaaacctacggtcggggccctttggactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +22108 JY8QFUQ01AYSDL No results +22109 JY8QFUQ01CAQJA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggGggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22110 JY8QFUQ01BJT4G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22111 JY8QFUQ01CB7ZQ productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 281 81.4 70/86 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame - Low V-REGION identity (81,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +22112 JY8QFUQ01DLR69 productive Homsap IGHV3-7*01 F 919 91.32 200/219 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARVRGYYGGQYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctgggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22113 JY8QFUQ01B32HS No results +22114 JY8QFUQ01BDDP0 No results +22115 JY8QFUQ01AFX4M No results +22116 JY8QFUQ01CIFVA productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 692 80.47 173/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame - Low V-REGION identity (80,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22117 JY8QFUQ01B6XEV No results +22118 JY8QFUQ01BUDX2 No results +22119 JY8QFUQ01AB4WK productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1093 98.67 222/225 nt 97.78 220/225 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-1*01 F 3 8 10 13 8.10.13 [2.17.38.11] CTRDRNICNPPFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'A' (1 nucleotides at position 199 to 199 in the user submitted sequence), (cause frameshift); gcttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacacaatacgccgcgtctgtgaaaggcagattcaacatcttaagagatgattccAaaaagcatcgcctatctgcaaatgaacagcctgaaAaaccgaggacacagccgtgtattactgtactagagataggaacatctgtaaccctccctttgactactggggccagggaaccctggtcatcgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +22120 JY8QFUQ01BSCX8 No results +22121 JY8QFUQ01B6LRP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22122 JY8QFUQ01CBRZI unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 937 92.24 202/219 nt 91.78 201/219 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [2.17.38.11] CARGMATAES## out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggGggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22123 JY8QFUQ01BPRUL unproductive Homsap IGHV3-33*03 F 932 92.2 201/218 nt Homsap IGHJ6*02 F 94 61.29 38/62 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDGGAVAGW#VVDVW out-of-frame + cgtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggttggacgttgtggacgtctggggccaagggaccacggtcgaccgtcgcctcagcctccagccaaggccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22124 JY8QFUQ01B5D2F productive (see comment) Homsap IGHV3-7*01 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGDYYYFGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); ctctggattcaccttGcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgagtcaccatctccagagacaacgcccggaactcactgtatctgcagatgagcagcctgagagccgaggacacggctctgtattactgtgcgagacaaactggggactattattacttcggcctggacgtctggggccaaggaaccacggtcaccgtctcttcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22125 JY8QFUQ01CFWZO unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 168 92.31 36/39 nt 8 X X 8.X.X [2.3.X.X] null + No rearrangement found gcctctggattcacctttaacagccatgccatgagttgg +22126 JY8QFUQ01C1C5K productive (see comment) Homsap IGHV3-7*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 7 8 14 7.8.14 [2.17.38.11] CATSPFTVTTGKDAYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift) gcctctagattcacctttaatggtactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22127 JY8QFUQ01CR8C5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.15 204/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKIDSRNYDFWSGYYAHW in-frame + gcctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtttattactgcgcgaaaatagatagtcggaattacgatttttggagtggttattatgcacactggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgggaactcag +22128 JY8QFUQ01BNYOH productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaAaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22129 JY8QFUQ01CLL77 productive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1028 96.38 213/221 nt 95.93 212/221 nt Homsap IGHJ6*02 F (see comment) 238 87.1 54/62 nt Homsap IGHD2-8*01 F 2 10 7 14 10.7.14 [1.17.38.11] CASTSGSDYHYGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); tttctggtggctccatcagcagtggtggttactactggagctggatccgccagtaccCccgggaagggcctggagtggatggggtacatctattacagtgggagcacctattacaacccgtccctcgagagtcgagttaccatatcagtagacacgtctaagaaccagttctccctgaagctgagctctgtgattgccgcggacacggccgtctattactgtgcgagtactagtgggtcagactaccactacggaatggacgtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +22130 JY8QFUQ01BCTYE unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGFSAWGQDAFDI## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttgggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccattccggtccttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtggacggtgtcgtggaactc +22131 JY8QFUQ01AXZ3Q productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22132 JY8QFUQ01C4HGG No results +22133 JY8QFUQ01CRZTN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt 87.61 191/218 nt 8 8 X 8.8.X [2.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 45 in the user submitted sequence), (cause frameshift) gcctctggattcacctttaccacctccgccatggcctgggtccgcaggttccagggaaggggctgaagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22134 JY8QFUQ01AHEE4 productive (see comment) Homsap IGHV3-7*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [2.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) gcctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22135 JY8QFUQ01DFTAV unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 833 87.16 190/218 nt 86.7 189/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-6*01 F 2 8 7 X 8.7.X [2.17.38.11] CVRSYSRTSE#FDYW out-of-frame + stop codons in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) gcgtctggattcagtttcagtacctttggcatgagttggatccgccagacgccaggcaaggggctggagtgggtgacagttatatggtcggatggaactaaaaaaattatgcagactccgtgaagggccgattcaccatctccagagacaatgtcaagaacacggtttatctgcagatgagcagcctaagagtcgaggacacgggcgtatattattgtgtgaggtcgtatagtaggacatctgagttttgactactggggcccgggaacccaagtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22136 JY8QFUQ01BAQLF productive Homsap IGHV3-7*03 F 847 87.67 192/219 nt Homsap IGHJ6*03 F (see comment) 156 78.43 40/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [2.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) gcctccggattcacttttagtgactattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatcgggaacgtggtcatcgctgcctggtccagggctcttccccca +22137 JY8QFUQ01AKUO2 No results +22138 JY8QFUQ01DAH7T productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 955 93.15 204/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 2 9 7 12 9.7.12 [2.17.38.11] CVRHRRLELLPDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'AATA' (4 nucleotides at position 25 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'CA' (2 nucleotides at position 61 to 62 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 34 of V-REGION: 3 nucleotides (from position 22 in the user submitted sequence), (do not cause frameshift) gtctctggtgactccatcagcagtAATAgttttctactggggctggatccgccagcccccCAgggaagggggctggagtggattgggaatatctattatagtgggagcacctactacaaccCcgtccctcgagagccgagtcaccatatccgtagatacatccaggaaccagttctccctgaagctgaggtttgtgaccgccgcagacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22139 JY8QFUQ01CS2TL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDCDSGECNFDYW in-frame + gcctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22140 JY8QFUQ01DJEW5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagccacagcggccctgggctgcctggtcaaggacctacttccccgaaccggtgacggtgtcgtggaact +22141 JY8QFUQ01DB11U productive (see comment) Homsap IGHV3-48*02 F 960 93.18 205/220 nt 91.36 201/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARDMIIFGGALDNW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 108 to 108 in the user submitted sequence), (cause frameshift); tgcctctggattcgccttcagtagttccagcatgaactgggtccgccaggGgtccagggaaggggctggagtggAttttcacacattagGgggtagtagtagtaccaCcccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggagcccttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtccgtcgcatcgcctggtccagggcttcttcccccgag +22142 JY8QFUQ01B4LNG No results +22143 JY8QFUQ01CUNKZ No results +22144 JY8QFUQ01BG7JJ No results +22145 JY8QFUQ01AV68L unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.13 193/219 nt 87.67 192/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcCaaaaagtatggcatgaactggctccgccaggctccagggaaggggctggantgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagcgggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +22146 JY8QFUQ01COR8B productive Homsap IGHV3-7*01 F 806 85.78 187/218 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARVKASGVRPMNAYDMW in-frame + cctctggattcgtgtttagtgactactggatgagttgggtccgccagcctccagggaaggggctggagtgggtggccagcattaaggaagatggacgtgagacgtactctgtggactctgtgaagggccgtttcaccatctccagagacaacgccgtacgttctctccttctacaaatgaacagactgagagtcgaggacacggctgtttatttctgtgcgagagtcaaggcttccggggtnaggcccatgaatgcctatgatatgtggggccaagggacattggtcaccgtctcttcagcctccaccaaggcccatcggtcttcccccctggcaccctcctccaagagcaccctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +22147 JY8QFUQ01B7R66 No results +22148 JY8QFUQ01B0JYF No results +22149 JY8QFUQ01B4SDT productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 823 87.04 188/216 nt 86.11 186/216 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD1-26*01 F 3 8 7 11 8.7.11 [2.17.38.11] CATLRGGYFRLLG in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); gtctctggtgcctccatcaggagttattattggagttggatccggcagccCcccaggaaagggactggagtggattggttatattaattatgttgggggAcaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagaggggggtactttcgactactgggggccgggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +22150 JY8QFUQ01CJ3LH unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 941 92.66 202/218 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDLRVSTMASD#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggtctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaaggactacttccccgaaccggtgacggtgtcgtggaactc +22151 JY8QFUQ01BHHPO unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 937 92.24 202/219 nt 91.78 201/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [2.17.38.11] CAKGV*QWL##DFDCW out-of-frame + stop codons in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtagttTttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggccaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +22152 JY8QFUQ01ADN1T unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 92.99 199/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaAaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +22153 JY8QFUQ01CJVC7 productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame - cctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22154 JY8QFUQ01CBLRN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); cctctggattcacctTttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc +22155 JY8QFUQ01BYZGI unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGGG# out-of-frame + in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cctctggattcacTttttagcagccatatgatgagttgggtccgccaggctccagggaaggGggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggggaccagggagccctggtctccgtctcctcagcatcccccgaccagcccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +22156 JY8QFUQ01B9LAE productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 856 88.13 193/219 nt 87.67 192/219 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.16.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) gcctccgggattcacctttagtagtttctggatgcactgggtccgcaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgcctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22157 JY8QFUQ01BOOGP productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +22158 JY8QFUQ01DL109 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); ctccggattcaccGtttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccaaccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22159 JY8QFUQ01BQ7IE productive (see comment) Homsap IGHV3-7*03 F 851 88.07 192/218 nt 87.16 190/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); cctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggGAagggggctggagtGgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +22160 JY8QFUQ01AY0CF productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22161 JY8QFUQ01B4PHJ productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 849 87.0 194/223 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD4-23*01 ORF 3 8 10 14 8.10.14 [1.17.38.11] CSRRSTLVTGYVFDKW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggaatcaactttcgtgatcatgccatgagctggttccgccaggttccagggaaggggctggagtgggtaggtttcattagaagttctcaatacggtggagatacagaatacgccgcgtctgtggaaggcagattcaccatctcaagagacgattccaaaagcatcgcctatttggatatgaatagcctgaaaatcgacgacacagccctatattactgttcccggaggtcgacgttggtgactggatacgtctttgacaagtggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22162 JY8QFUQ01A4FKP No results +22163 JY8QFUQ01CH8AQ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 163 92.11 35/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found cctctggattcaccttcagtgtccatagcatgaactgg +22164 JY8QFUQ01DSHGG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 888 89.55 197/220 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacatttcgccttttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggaatggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22165 JY8QFUQ01BV2N1 No results +22166 JY8QFUQ01DB2AC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F (see comment) 87 64.58 31/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaacccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +22167 JY8QFUQ01B8G5P unknown (see comment) Homsap IGHV4-30-2*01 F, or Homsap IGHV4-30-2*02 F or Homsap IGHV4-30-2*03 F or Homsap IGHV4-30-2*05 F or Homsap IGHV4-30-2*06 F or Homsap IGHV4-30-4*01 F or Homsap IGHV4-30-4*02 F or Homsap IGHV4-30-4*03 F or Homsap IGHV4-30-4*04 F or Homsap IGHV4-30-4*07 F or Homsap IGHV4-31*01 F or Homsap IGHV4-31*02 F or Homsap IGHV4-31*03 F 76 94.12 16/17 nt 4 X X 4.X.X [1.X.X.X] null + No rearrangement found tctctggtggcgccatc +22168 JY8QFUQ01BY1J1 productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.18 194/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactGactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22169 JY8QFUQ01CTORM unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt 8 8 X 8.8.X [1.17.38.11] CTTTLVWFGGV (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION in FR2-IMGT at codon 48 of V-REGION: 'GG' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift); cctctggattcacgtttagagactattggatgagttgggtccgccaggctcctggggaGGggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcgggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22170 JY8QFUQ01CLG7Y unproductive Homsap IGHV3-7*01 F 937 92.24 202/219 nt 91.78 201/219 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [2.17.38.11] CARWRGQQSEME#YW out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggGggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaagtactggggccagggaaccctggtcaccgtctctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22171 JY8QFUQ01DSPF1 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 683 79.63 172/216 nt 76.85 166/216 nt Homsap IGHJ3*01 F 106 68.0 34/50 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [2.17.37.11] CARDDGGHM#LDVW out-of-frame - stop codons Low V-REGION identity (79,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 42 of V-REGION: 'GT' (2 nucleotides at position 41 to 42 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'CAGG' (4 nucleotides at position 86 to 89 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 82 of V-REGION: 'C' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 170 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 177 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 94 of V-REGION: 1 nucleotides (from position 187 in the user submitted sequence), (cause frameshift) atgtctggattcacatttagaagctattcctgaaattgggGTccgcccaggctccagggaaggggctggaatgggtctcagctgtCAGGtggtggtggggggcgccgacgaaactacgcggagtccgtgaagggccggttcaccatctccagaggcnCaattcagggggacggtgttctacaatgaacagcctagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgacttagatgtctggggccaagggacaatggtgcagcgtctctccggcctccaccaaggggcccatcgggtnttccccctgcaccctcctcccaagagccacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaactcaggc +22172 JY8QFUQ01BY1PJ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactGgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22173 JY8QFUQ01CIYD1 unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt 8 8 X 8.8.X [1.17.38.11] CTTTLVWFGGV (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcgggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22174 JY8QFUQ01BMR9L productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22175 JY8QFUQ01AGYSC No results +22176 JY8QFUQ01B21BT productive Homsap IGHV3-13*01 F 967 94.44 204/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame + ccctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +22177 JY8QFUQ01AONPX unproductive (see comment) Homsap IGHV3-7*01 F 992 94.57 209/221 nt 94.12 208/221 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); cgacctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22178 JY8QFUQ01DKQJ9 productive Homsap IGHV3-48*01 F 860 88.53 193/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + tctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22179 JY8QFUQ01B5F9V No results +22180 JY8QFUQ01C7SUZ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 976 94.91 205/216 nt 93.98 203/216 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.16.38.11] CARDPVGISGSVNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagcaaccataacatgaactgggtccgccagctccagggaacgggctggagtgggtctcGatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaacggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22181 JY8QFUQ01BMDA4 unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*02 F or Homsap IGHV3-33*03 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F or Homsap IGHV3-64*01 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 123 54.35 75/138 nt 8 8 X 8.8.X [2.17.10.X] null - No rearrangement found stop codons agcgtctggattcaccttcagtagctacggcatgcactgggtccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +22182 JY8QFUQ01B1Y93 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22183 JY8QFUQ01CQ5SG productive Homsap IGHV1-8*01 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 12 8.8.12 [0.17.38.11] CARGRGYGSYADHW in-frame + tggatacagcttcagcaattatgatatcaactgggtgcggcaggccactggacaagggcttcagtggatggggtggatgaacccccacagtgccaatatcgtctacgcgcagaaatttcagggcagagtcaccatgaccagtgacgcctccataaccacagcctacatggaactgagcaacctgaaatctgacgacacggccgtgtattattgtgcgaggggccgagggtacggaagttacgctgaccactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22184 JY8QFUQ01AV599 productive (see comment) Homsap IGHV1-8*01 F 840 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARVGGTHYHYGVDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); cggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaAagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagatctgacgacacggccgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22185 JY8QFUQ01CH46O productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.16.38.11] CARFGPLTRPDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) gctctggattcaccttcagcaagtatgCccatgagctgggtccgccaggctccaGgggagggggctgcagtgggtctcagaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatctccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +22186 JY8QFUQ01CAKUG productive (see comment) Homsap IGHV3-23*05 F 820 86.3 189/219 nt 85.84 188/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [2.17.38.11] CVKSTGHSGWYPFDNW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcacattcagcaattatgccatgggctgggtccgccaggctccagggaaggGggctggagtgggtcgctgctattgatggcagtggtgaaagaactcactatgcagactccgaacagggccgcgtcaacatctctagagacaattccaagaacatgatatatgtgcaattgagcagcctgagagccgaggacacggccatgtattactgtgtgaagtccaccgggcacagtggctggtatccctttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +22187 JY8QFUQ01BAT68 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); ctctggatcaccctttggttattGatggcatgagctgggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22188 JY8QFUQ01CQJDE unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 788 92.82 168/181 nt 8 8 X 8.8.X [2.17.25.X] null + No rearrangement found gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattga +22189 JY8QFUQ01BVL75 unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDPFIAATGRPWYFEYW in-frame + stop codons cctctggattcaccttcagcagctatggcatgcactggttccgccaggctccaggcaaggggctggagtgggtggcagctatctcatatgatggaattgacaaatattatgcagactccgtgaagggccgattcaccatctccagagacaatgccaaaaacacgctgtatctgcaattgaacagcctgagaagtgaagacactgctgattactactgtgcgaaagacccatttatagccgcaactggccgcccctggtactttgaatactggggccagggaaccctggtcaccgtctcctagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22190 JY8QFUQ01ATEC0 unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 925 92.96 198/213 nt 92.49 197/213 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD1-26*01 F 1 8 7 X 8.7.X [1.16.38.11] CARVVTATIYTGSYYFDS## out-of-frame - in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) ctatggtgcgtccttcagtgattactcctgggcctggatccgccagtcccagggaaggggctggagtggattggagagatcaatcatagtggaagcaccaactacaacccgtccctcaagagtcgaggcatcatatcaatagacatgtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacacggctgtatattactgtgcgagagtcgtcacggctacaatttatactgggtcctactactttgactcctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +22191 JY8QFUQ01C67PP productive Homsap IGHV3-7*03 F 851 88.07 192/218 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctccggattcatttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +22192 JY8QFUQ01B1RYY unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 155 56.83 79/139 nt 56.12 78/139 nt 10 7 X 10.7.X [1.17.10.X] null + No rearrangement found stop codons in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactggGggctggatccgccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +22193 JY8QFUQ01A6JX4 productive Homsap IGHV3-48*02 F 891 90.32 196/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [1.17.38.11] CARGQKWLQVLRWFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +22194 JY8QFUQ01BN5HY unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 165 57.45 81/141 nt 10 7 X 10.7.X [1.17.11.X] null + No rearrangement found tctctggtggctccatcagcagtagtagttactactggggctggatccgccagccccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +22195 JY8QFUQ01CBUKV unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSDFYSTGH## out-of-frame + in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); ctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgTtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22196 JY8QFUQ01A896V productive (see comment) Homsap IGHV3-7*01 F 865 88.58 194/219 nt 87.67 192/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDPYKPGSGNPGFDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); gcctctggattcaccttTtagtgactatttgatgacttgggtccgccaggctccaggaaagggactggagtgggtggccaacataaAaagaagatggacttgctacattctatgtggactctgtgagggaccgattcaccatctccagagacaacgccaagaactcactttatttgcaaatgaattacctgagagtcgaggacacggctgtttattattgtgcgagggatccctataaacctggttcgggcaatccgggctttgactactggggccagggagcgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +22197 JY8QFUQ01CGLJ5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 995 95.41 208/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame + cctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc +22198 JY8QFUQ01AMLL4 No results +22199 JY8QFUQ01AEIPV productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 81 to 86 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +22200 JY8QFUQ01COBUV unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1001 95.02 210/221 nt 93.67 207/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-7*01 F 3 10 7 X 10.7.X [1.17.38.11] CVRHRRLELLPDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagcagtaatagtTttctactgGgggctggatccgccagcCccccagggaaggggctggagtggattgggaatatctattatagtgggagcacctactacaacccgtccctcgagagccgagtcaccatatccgtagatacatccaggaaccagttctccctgaagctgaggtttgtgaccgccgcagacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +22201 JY8QFUQ01AQ576 productive Homsap IGHV3-7*01 F 977 94.5 206/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDGYYYYHSGMDVW in-frame + cctctggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattattgtgcgaaagacggctattattattatcacagcggtatggacgtctggggccaagggaccacggtcatcgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +22202 JY8QFUQ01AX5J6 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.1 219/221 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANYW# out-of-frame + in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactgGgggctggatccgccagcCccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22203 JY8QFUQ01CEKZ5 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKVYTGAWGDPNFDS# out-of-frame + ctctggattcagctttagcaactttgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtacttttagcacccattatgccgactccgtgaagggccgcttcaccatctccagagacaatttcaggagcaccttatatctgcagatgaacaacctgagagccgacgacacggccatatattactgtgcgaaagtgtacaccggtgcctggggggatcctaattttgactcctgggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +22204 JY8QFUQ01CBUHY unproductive Homsap IGHV3-53*04 F 791 85.58 184/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CARQTAPLWG#FDLW out-of-frame + ctcgggggttcaccgtccaaaacagcttcatgagttgggtccgccaggctccagggaagggcctagagtgggtctcagttgtttatagtggtggatccacatactacgcagactccgtgaagggccgtttcaccatcgccagacacagtcgcaacaacattctgtatcttcaaatgaacagcctgagacctgaggacacggctgtttacttctgtgcgagacagactgcccccctttggggaactttgacttatggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga +22205 JY8QFUQ01BNV04 unknown (see comment) Homsap IGHV3-74*03 F 120 54.55 72/132 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +22206 JY8QFUQ01ASJB1 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 959 89.45 212/237 nt 87.76 208/237 nt Homsap IGHJ3*02 F (see comment) 133 74.0 37/50 nt Homsap IGHD2-2*01 F 3 8 7 X 8.7.X [9.17.38.11] CASSVFSPGGFNY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'GT' (2 nucleotides at position 102 to 103 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 148 to 148 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 82 of V-REGION: 'G' (1 nucleotides at position 173 to 173 in the user submitted sequence), (cause frameshift); tctctgaagatctcctgtgcagtttcggggttcaccgtcagtagcaagtacatnacctgggtccgccaggctccggggaaggggActggagtctgtctctgGTttttttatagcggtgatcaaacatactacgcagactccgtgaggGggccgattcaccatctccatagacGaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttaactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag +22207 JY8QFUQ01B288U No results +22208 JY8QFUQ01BP7KB unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1086 99.55 219/220 nt 99.09 218/220 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [2.17.38.11] CARGHCISTSCYWGD##YYYGMDVW out-of-frame + in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggGAagggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattggggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatnggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaact +22209 JY8QFUQ01B0MI7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +22210 JY8QFUQ01CGZFF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.37.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +22211 JY8QFUQ01AOJGK productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgGacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22212 JY8QFUQ01BD04C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKGLYYYDSSGYRVFDYW in-frame + ctctggattcacctttagcaactttgccatgagctgggtccgccaggctccagggaagggactggagtgggtctcgactattagtcctagtggtggtaccacatattacgcagactccgtgaagggccggttcaccatctccagagacagttccaagaacacgctgtatctgcaaatgaacatcctgagagccgaggacacggccacatattactgtgcgaaaggactatattattatgacagtagtggttatcgggtctttgactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +22213 JY8QFUQ01CMDQ5 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 942 92.27 203/220 nt 91.36 201/220 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-11*01 ORF 1 8 8 X 8.8.X [2.17.38.11] CAKSGG*CPLETALTT## out-of-frame - stop codons in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); agcctctggattcaccGtttagcaactatgccatgagttgggtccgccaggctcaagggaaTggggctggactgggtctcagatattagtaatagtggtggtgacacattctacgcaggctccgtgaagggccgcttcaccatctccagagacaattccaggaacactctatatctgcaaatggacagcctgagagccgaggacacggccgtgtattactgtgcgaaaagtggggggtgatgtccgctcgagaccgcattgactacttgggggccggggaaccctggtctccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +22214 JY8QFUQ01B3DFL productive Homsap IGHV3-30*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [1.17.38.11] CVKNDLSWGTIEHYFDYW in-frame + ctctggattcacgttcaacatttatggtctacactgggtccgccaggctccagggcaagggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22215 JY8QFUQ01CK61T productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDQYGSPSDFDNW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'GGA' (3 nucleotides at position 84 to 86 in the user submitted sequence), (do not cause frameshift); cctctggtttcacatttagtacgtactggatgagttgggtccgccaggctcccggaaaggggctggagtgggtctcggctattGGAggtgttgatgatgttggcacatactacgcagcctccgtgaagggtcggttcaccatatccagagacgattccagggagattctctatctacaaatgagtaacctgagagtcgacgatacggccgtctattactgtgcgaaagatcaatatgggagcccatccgactttgacaactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22216 JY8QFUQ01C39T0 productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame + ctctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22217 JY8QFUQ01B7PA7 unknown (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F (see comment) 289 66.44 97/146 nt 8 8 X 8.8.X [2.17.13.X] null + No rearrangement found Low V-REGION identity (66,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +22218 JY8QFUQ01AKF8Q productive Homsap IGHV3-7*01 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaatcctggtcaccgtctcctcagcctccacccaaggggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22219 JY8QFUQ01AIAM0 productive Homsap IGHV4-4*07 F 823 87.04 188/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [2.17.38.11] CARQRGGGDRQWAFENW in-frame - gtctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22220 JY8QFUQ01BZKTI unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); ctccggattcGacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaAactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag +22221 JY8QFUQ01CN5XU productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 851 88.07 192/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-2*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDRTLHTPAQMSYYGMDVW in-frame + catctggattcaccttcagttcttatagtgtaaactgggtccgccaggctccagggaagggcctagagtttgtctcatacattgatagtagtggttctaccatatactacgcagactctgtgaagggccgattcaccatctctagagacaatgcccagaactcactgtttctgcaaatgaacaacctgcgagtcgacgacacggccgtatattactgtgcaaaagaccggacacttcacacacccgctcagatgtcttactatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatctccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccgag +22222 JY8QFUQ01CLR99 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [1.17.38.11] CAKEGNLGYFDDW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22223 JY8QFUQ01CS2FC unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 172 57.53 84/146 nt 8 8 X 8.8.X [1.17.14.X] null + No rearrangement found ctctggattcatctttgatgattttggcatgagatgggtccgccaagttccggggaaggggctacagtgggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +22224 JY8QFUQ01ATKM1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcncatgcctggtccagggcttcttccccca +22225 JY8QFUQ01BRMO4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ1*01 F 89 63.46 33/52 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame + in FR3-IMGT at codon 83 of V-REGION: 'T' (1 nucleotides at position 153 to 153 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatTttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagtacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgncgtgtcgtggcaactcagg +22226 JY8QFUQ01CBGMQ productive (see comment) Homsap IGHV3-48*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDMIIFGGALDNW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggattcgccttcagtagttccagcatgaactgggtccgccagggtccagggaaggggctggagtggatttcacacattaGggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggagcccttgacaactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgccctgcctggtccagggcttcttc +22227 JY8QFUQ01CNFBY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22228 JY8QFUQ01B7H6T unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 823 95.53 171/179 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatg +22229 JY8QFUQ01BEB1K productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 847 87.67 192/219 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-2*01 F 3 8 8 19 8.8.19 [2.17.38.11] CAKDRTLHTPAQMFYYGMDVW in-frame - gcatctggattcaccttcagttcttatagtgtaaactgggtccgccaggctccagggaagggcctagagtttgtctcatacattgatagtagtggttctaccatatactacgcagactctgtgaagggccgattcaccatctctagagacaatgcccagaactcactgtttctgcaaatgaacaacctgcgagtcgacgacacggccatatattactgtgcaaaagaccggacacttcacacacccgctcagatgttttactatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatctccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22230 JY8QFUQ01AMDCR unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F (see comment) 216 56.57 112/198 nt 10 9 X 10.9.X [2.17.28.X] null - No rearrangement found stop codons Low V-REGION identity (56,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccgggggacagtgtctctagcaacagtcctgcttgagactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22231 JY8QFUQ01CN9HF productive (see comment) Homsap IGHV4-61*08 F 874 89.04 195/219 nt 87.67 192/219 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-16*01 F 2 10 7 10 10.7.10 [1.16.38.11] CTRGGYTYDSPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'C' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 206 to 206 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift) ctctggtgcctccatcagcagtagtggtcactactggagttgatccggcagcccccagggaagggCactggaattcattggaaaaatctattccaatgggaacgccaactacaacccctccttcaagagtcgagtcaccatttcagtggacacgtccgagaaccagttctccctgagcctgaggtctgtgaccgctgcggacacgGgccctttattactgtacgagggggggatacacttatgacagcccgtggggccaggggattcaggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22232 JY8QFUQ01AH0PS productive (see comment) Homsap IGHV1-3*01 F 848 89.15 189/212 nt 88.21 187/212 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [0.16.37.11] CARDGEPLGGDYLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 51 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 83 of V-REGION: 1 nucleotides (from position 150 in the user submitted sequence), (cause frameshift) tggatataccttcacttattacgctataaattgggtgcgccaggcccccgagaaaggcctgagtggatgggatggatcaaccctggcaacggtaatacaaaatattcacagaagttccaggacagactcacctttaccagggacacatcgcgaacacagtttccatggaactgagtagcctgcgatctggagacacggctgtgtattactgtgcgagagatggggagccactgggaggcgactacttggactactggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22233 JY8QFUQ01C5H9S productive Homsap IGHV4-39*02 F 938 91.86 203/221 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-9*01 F 1 10 7 18 10.7.18 [1.17.38.11] CARLLRVYDWYSQRGYFDTW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctccgatggctccatcagcactagtaattactactggggctgggtccgccagcccccagggaaggggctggagtggattggaagtatatattatagtgggagcaccgactacagctcgtccctcaggagtcgcgtcaccatatccagagacacgtccaagaaccacttctccctgaaggtgacctctgtgaccgccgcagacacggctatatattactgtgcgagactcttacgggtttatgactggtacagtcaaaggggttacttcgacacctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgggtgtcgtggaactc +22234 JY8QFUQ01BVAZ6 productive Homsap IGHV4-61*02 F (see comment) 794 84.62 187/221 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARAKDHDDYLVDPW in-frame + Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgcctccatcactagtggtacttactactggagttggttccggcagcccgccgggaagacactggaatgggttgggcgtatctatacaactgggagcacctattacaacccctctctcaaaagccgagtcaccgtttcagtcgacgagtcccagaatcagctcttcctggacctgacttctgtgaccgccgcggacacggccgtctacttctgtgcgcgagctaaggaccacgatgactacctggtcgacccctggggccaggggatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +22235 JY8QFUQ01A64UI unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 967 94.44 204/216 nt 93.52 202/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 2 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) cctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggAaaaagggctggagtggatctcagcttttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22236 JY8QFUQ01CY31M productive (see comment) Homsap IGHV3-9*01 F 802 85.39 187/219 nt 84.47 185/219 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-9*01 F 2 8 8 16 8.8.16 [2.17.38.11] CVKDLSGRPKDMHGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); gcctctgggttcaggtttagcaattatgccatgcactgggtccgtcaagctccagggaaAgggcctgcaatgggtctcacgtaCttaattggaacagtggaaacatagcctatgcggcctctgtgaggggccgattcaccgtctccagagacgacgccgagcactccctgtatttacaaatgaatggtctgacaactgaagacacggccttatactattgtgtgaaagatttgtctggccgaccaaaggacatgcacggcatggacgtctggggccaagggaccacggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22237 JY8QFUQ01A8GGU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cgtctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22238 JY8QFUQ01BAK4Q No results +22239 JY8QFUQ01BH5VO No results +22240 JY8QFUQ01CJPO4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 961 94.84 202/213 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [X.17.38.11] CARGPRSRGYGMDVW in-frame + ggattcacctttagcagctatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag +22241 JY8QFUQ01AKNWR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 784 84.47 185/219 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [2.17.38.11] CARDSGSSDYTRYDAQDVW in-frame - Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctgctggattagttttagttcttatgggcatgaactgggtccgccaggctccagggggggggctggagtgggtctcattcattaacagtgttagtagttacaaatactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaagaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagatagcggctcgtccgactacactaggtacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22242 JY8QFUQ01A7IRE No results +22243 JY8QFUQ01AU6BC unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 706 81.02 175/216 nt 80.09 173/216 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD3-3*01 F 3 8 7 X 8.7.X [2.17.38.11] CARAYTFFTF*EWPH#WYSDLW out-of-frame + stop codons Low V-REGION identity (81,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); gtctctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaGggggctggagtggattgGgggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatacttttttcactttttaggagtggcctcacactggtactccgatctctggggccgtggcaccctggtcacagtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtgcagggcttcttccccca +22244 JY8QFUQ01C4W37 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.52 202/216 nt 92.59 200/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); tctggattcaTcgttcagtagcGtatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtantggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22245 JY8QFUQ01BQMPO No results +22246 JY8QFUQ01A4UI3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 938 91.86 203/221 nt 90.95 201/221 nt Homsap IGHJ6*02 F (see comment) 256 90.32 56/62 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [2.17.38.11] CAHGPSAAPHYYYYYGLEAW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift); aggcctctggattTcacctttaccaactatgGgcatgaggtgggtccgccaggctccagggaaggggctggagtgggtctcagatattagcgctggtggcgataacacatactacgcagactccgtgaagggccggttcaccatctccagagacaatttcaggaacacgctgtatctgcaaatgagcagcctgagagccgaggacacggccctttattactgtgcgcatgggcccagtgcagcaccccattactactactattacggtttggaagcttggggccaagggaccaaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22247 JY8QFUQ01BGDEX productive (see comment) Homsap IGHV3-7*01 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); cctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacacgcgggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaact +22248 JY8QFUQ01A1FF8 No results +22249 JY8QFUQ01BK0SF unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 968 92.07 209/227 nt 90.31 205/227 nt 8 7 X 8.7.X [5.17.38.X] null + No rearrangement found in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); cagcctctgcagcctctggattcattgtcaatagcaactacatgagttGgggtccgccagGgctccagggaaGggggctggactgcgtctcagttatttatcccggtgGgtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaggggaacccctggtcaccgtgctcttcagcctccaccaag +22250 JY8QFUQ01CMTEA unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt 87.21 191/219 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [2.17.38.11] CAGSGRDPYGINV## out-of-frame + in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggGggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca +22251 JY8QFUQ01BCF8N unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 476 70.24 144/205 nt 8 8 X 8.8.X [1.17.34.X] null + No rearrangement found Low V-REGION identity (70,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +22252 JY8QFUQ01A8PYD unproductive Homsap IGHV3-9*01 F 887 89.91 196/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDVTSESHFFALDV## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctcgggattcaagtttgatgaatatgccatgcactgggtccggcgagttccagggaggggcctggagtgggtctcagttataagttgggatggtgatgacatcgcctatgcggactctgtgaagggccgattcagcatctccagagacaacgccaagaactccctgtacctggaaatgagcagtctgagagttgaggacacggccttctattactgtgcaaaggatgtcacatctgaaagtcacttcttcgctttggacgtctgggggccaagggaccgcggtcaacgtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22253 JY8QFUQ01CFYV1 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1057 99.07 214/216 nt 98.61 213/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [2.17.38.11] CARLGPGSGTDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttcctactggagctggatccggcagcCccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22254 JY8QFUQ01BZRQM productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt 91.4 202/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcCccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22255 JY8QFUQ01AQ0AZ unproductive Homsap IGHV3-7*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [1.17.38.11] CARGSYWHYDTFGDY## out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggGggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattgggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtgggcaactca +22256 JY8QFUQ01APPTA unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F 69 60.42 29/48 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CAREKGSGPPHRA#DVW out-of-frame - in FR3-IMGT at codon 93 of V-REGION: 'G' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift); ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggacGagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggccccccccacagggcatggacgtctggggcccagggaccatggtcacccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctccctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22257 JY8QFUQ01DMHUQ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'GC' (2 nucleotides at position 62 to 63 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'AG' (2 nucleotides at position 76 to 77 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggGCtgggagtgggtcAGtctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22258 JY8QFUQ01A5NTK unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found agttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +22259 JY8QFUQ01CUTV1 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 858 89.25 191/214 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame + ctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22260 JY8QFUQ01BHIXV unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.1 219/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtGagtagttactactGggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22261 JY8QFUQ01BAP2B productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.16.38.11] CVKGWNYHSATFGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) cctctggattcacctttagtgactatgccataagctgggtccgccaggctccagaaaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccattttcagagacaactccaaagacacgctgtatctgcaaatgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaacctttgggtttgactactggggccagggaaccctggtcaccgtctcctcacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22262 JY8QFUQ01B31RJ productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 881 90.23 194/215 nt 89.3 192/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'T' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); tttcggggttcaccgtcagtagcaagtacatTgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcgGgtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22263 JY8QFUQ01AGCNW unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 523 70.78 155/219 nt 8 8 X 8.8.X [2.17.38.X] null + No rearrangement found Low V-REGION identity (70,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22264 JY8QFUQ01C4VM3 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt 99.55 219/220 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANYW# out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccaggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22265 JY8QFUQ01BG27O productive (see comment) Homsap IGHV3-48*03 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagttcttatgccatgaactgggtcgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22266 JY8QFUQ01ALIXE unproductive Homsap IGHV3-11*06 F (see comment) 760 83.8 181/216 nt 82.87 179/216 nt Homsap IGHJ1*01 F 125 71.15 37/52 nt Homsap IGHD5-12*01 F 1 8 7 X 8.7.X [2.17.38.11] CSRDGRRGYDLDS## out-of-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01ALIXE ; 8 AA in Homsap_IGHV3-11*06), and low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'AC' (2 nucleotides at position 24 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); gcctctggattcacctttcgggaACctatgccatgacgtgggtccgcctgactcctgggaAaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctgggggccagggagccctggtcaccgtctcctcatcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +22267 JY8QFUQ01A4VB0 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 866 88.24 195/221 nt 87.78 194/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARQLSGDYASFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaccagtggtactttttactgggcctggatccgccagcccccagggaAaggggctggagtgggttggcaatatctattctagtggtgtcgcctattacaacccgtccctcaagagtcgagtcaccatgtccgtcgacacgtccaagaatgagttttccctgacactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22268 JY8QFUQ01CR4ZL productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22269 JY8QFUQ01BYM2X No results +22270 JY8QFUQ01CHX5X unproductive Homsap IGHV4-39*02 F 933 91.82 202/220 nt 90.91 200/220 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-9*01 F 2 10 7 X 10.7.X [1.17.38.11] CARLLRVYDWYSQRGLL#DTW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctccgatggctccatcagcactagtaattactactgGgggctgggtccgccagGcccccagggaaggggctggagtggattggaagtatatattatagtgggagcaccgactacagctcgtccctcaggagtcgcgtcaccatatccagagacacgtccaagaaccacttctccctgaaggtgacctctgtgaccgccgcagacacggctatatattactgtgcgagactcttacgggtttatgactggtacagtcaaagggggttacttcgacacctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22271 JY8QFUQ01C5DZY unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 371 88.3 83/94 nt 87.23 82/94 nt 8 3 X 8.3.X [2.17.X.X] null + No rearrangement found in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); aagcctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaaggggActggagtgggtggccagtataaagcagga +22272 JY8QFUQ01ALVU9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 796 85.65 185/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccagccaaggccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +22273 JY8QFUQ01B70VI unproductive Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 610 96.21 127/132 nt 95.45 126/132 nt Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-8*01 F 1 8 X X 8.X.X [2.3.31.11] CVRDVSLYSNDGYDAF#YW out-of-frame + Other possibilities: Homsap_IGHJ3*01 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 40 in the user submitted sequence), (do not cause frameshift) gcctctggattcatttttagtaacttttggatgagttggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagagacgtctccctttatagtaatgatggatatgatgcttttgatattggggccaggggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +22274 JY8QFUQ01A378B No results +22275 JY8QFUQ01CGATX unproductive (see comment) Homsap IGHV3-48*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGGTLRY##DYW out-of-frame + stop codons cctctggattcaccttcactagaagtcccatgaattgggtccgccaggctccggggaaggggctggaatgggttgcatacattagtagtgatggtagtaccctatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaaagacttactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagacggggggactctacggtactcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc +22276 JY8QFUQ01DJPRS No results +22277 JY8QFUQ01BMPOE No results +22278 JY8QFUQ01BVA9L productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 88.99 194/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 128 to 128 in the user submitted sequence), (cause frameshift); cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaGggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaaggGgccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctcccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22279 JY8QFUQ01CORXQ unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 915 90.5 200/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 10 7 X 10.7.X [1.17.38.11] CARQSFISRGSGR*I#YFEYW out-of-frame - stop codons in CDR1-IMGT at codon 34 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); ctcctggtggctccgtcagcagGtagcacttactactggggctggctccgccagtccccagggaaggctctggantggattgggactatccatcaCtagtgggagcacctaccagaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaggaaccagttctccctgaggctgagctctgtgaccgccgcagacacggctctttattactgtgcgagacaaagctttatttcgcgtggcagtggcaggtagattattactttgaatactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22280 JY8QFUQ01AOWYJ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 748 82.19 180/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 10 8.8.10 [2.17.38.11] CAKDDSAGLDHW in-frame - Low V-REGION identity (82,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctccggattcatcttcagtgccgcttggatggagtgggtccgccaagttccagggcaggggctcgtgtgggtcgcgcgtatcgagagtagtggcagcggcacactttacgcggactacgtgaagggccgattcaccgtctccagagacaacgccatgaacatagtgtatcttcaaatgaattctctgactgccgaggacacgggtgtgtattactgcgcaaaggatgattcggccggccttgaccattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22281 JY8QFUQ01BXMZP unknown (see comment) Homsap IGHV4-61*02 F 879 88.69 196/221 nt 10 7 X 10.7.X [1.17.38.X] null - No rearrangement found tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttntgtgcgagagatttttggaggttcctacaattttagtggcctactgggggccaggggaaccctgggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22282 JY8QFUQ01CVWQE No results +22283 JY8QFUQ01AGKMG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1017 96.77 210/217 nt 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD1-1*01 F 3 8 8 8 8.8.8 [2.17.37.11] CAVNWNLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 75 of V-REGION: 1 nucleotides (from position 132 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 156 in the user submitted sequence), (cause frameshift) gcctctggattcacctttagcggctatgccatgagctgggtccgccaggctccagggaaggggctggactgggtctcatctattagttataatggtggtagcacatactacgcagactccgtgaagggccgttcaccatctccagagacaattccagaacacgctgtatctccaaatgaacagcctgagagccgaggacacggccgtatattactgtgctgtgaactggaaccttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22284 JY8QFUQ01BZPUF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 922 92.13 199/216 nt 90.74 196/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'T' (1 nucleotides at position 153 to 153 in the user submitted sequence), (cause frameshift); tctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaagGgggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgCaggggccggttcaccatctccagagacaacTcccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgcccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22285 JY8QFUQ01AKWRH unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 136 52.36 100/191 nt 8 8 X 8.8.X [1.17.30.X] null + No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22286 JY8QFUQ01DC7HF unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1043 98.6 212/215 nt 96.28 207/215 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CARLGARFGD*LL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'TAG' (3 nucleotides at position 56 to 58 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'GC' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctactgGgagctGggatccggcagccccccTAGgggaagggGCactggagtggattgGggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgggggcccggttcggggactgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaccggtgacggtgtcgtggaactc +22287 JY8QFUQ01DD5Q8 unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1007 94.64 212/224 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 X 8.10.X [1.17.38.11] CTTGGWN*L##W out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacaggggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22288 JY8QFUQ01CK636 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-10*02 F 2 8 7 X 8.7.X [1.17.38.11] CAKESLFGESS#YYFDDW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) cctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggtttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctgttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22289 JY8QFUQ01AV9WM productive (see comment) Homsap IGHV3-66*02 F 957 94.39 202/214 nt 92.99 199/214 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 7 11 8.7.11 [1.17.38.11] CARGGRGLRMTTG in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 97 of V-REGION: 'C' (1 nucleotides at position 193 to 193 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagGggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagaggtCgacgacacggctgtgtattactgtgcgagagggggacgggggttaaggatgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22290 JY8QFUQ01A8VKJ No results +22291 JY8QFUQ01CDQVB productive (see comment) Homsap IGHV2-5*02 F, or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F 909 86.07 210/244 nt 84.84 207/244 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-11*01 ORF 1 10 7 11 10.7.11 [9.16.38.11] CAHFGPQEHFDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'A' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'GG' (2 nucleotides at position 216 to 217 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) agactctcaccctgacctgcgacttctctggattctcactcagcacaAaatggtatggctgtgggctggatccgccagcccccgggagaggcccggagtggctcgcacacatttattgggatgatgatcggcgataccggccatccctagagaggaggctcaccatcaccaaggacatctccacaagcaaggtggtccttacaatgaccgacatgGGgcccctgcagacacagccacatacttctgtgcacactttggaccacaagaacacttcgacttttggggccagggaatcctggtcactgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag +22292 JY8QFUQ01DOLOU productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F 840 88.32 189/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARISAFDQW in-frame + acacggcgggtccttcaaaggttactattggagctggatccgccagcccccaggaaaggggctggagtggattggagaaatcgaccatagtggaaacaccaactacaacccgtccctcaagagtcgagtcaccgtgacagttgacacatccaagaaccaaatttccctgaatttgacctctgtgaccgccgcggacacggctatttattactgtgcgcgtatttcagcctttgaccagtggggccagggaaccccggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg +22293 JY8QFUQ01A5LZ5 No results +22294 JY8QFUQ01CAJR1 productive Homsap IGHV3-48*01 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-21*02 F 3 8 8 9 8.8.9 [2.17.38.11] CARDQVTEDYW in-frame + gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22295 JY8QFUQ01BWLHZ productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 964 93.61 205/219 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [2.17.38.11] CAREVSDAFEMW in-frame - gcctctggattcatctttgatgattttggcatgaattgggtccgccaagctccagggaaggggctggagtgggtcgctggtatcagttggaatggtggcaaagcaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcaatgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22296 JY8QFUQ01BAIZZ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 662 77.98 170/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (77,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactca +22297 JY8QFUQ01B5K5P productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 793 84.55 186/220 nt 84.09 185/220 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); aatctctggattcactctcagcagttttacactgaattgggtccgccaggctccggggaaggggctggantgggtActcatctataagtagtaccagtacttacaagcattatgctgacacggtggagggccgattcaccatctccagagataacgccaagaactcagtgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +22298 JY8QFUQ01B1P1F unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 719 85.28 168/197 nt 84.77 167/197 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) tctgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg +22299 JY8QFUQ01B2K3A unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGWFGAR#DYW out-of-frame - ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaagggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgtgtcgtggaactcag +22300 JY8QFUQ01APBXM unproductive Homsap IGHV3-9*01 F 848 89.15 189/212 nt 88.68 188/212 nt Homsap IGHJ1*01 F (see comment) 80 61.54 32/52 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.36.11] CSKDRYHFDSSQHAMDVW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 82 of V-REGION: 6 nucleotides (from position 150 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttggtgactttgccatgcactgggtccgacaacctccagggaagggcctggagtgggtcgcgactattagttggaggaatattagtagaggctatgcggactctgtgaagggccgattcaccatctccagagacaagaactccctgtacttgcaaatgaacactctgagatcagaggacacggccttctattattgttcaaaagacaggtatcattttgatagtagtcagcacgctatggacgtctgggggccaagggacccccggtcaccgttttctcagcctccaccaagggcccatcgggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +22301 JY8QFUQ01ARBGD unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); cctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataGggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctgggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22302 JY8QFUQ01B41JB unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 157 to 157 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 178 to 178 in the user submitted sequence), (cause frameshift); cctccggattcaccGtttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccAaagaacaggctgtatctgcaAaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgatagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +22303 JY8QFUQ01BOLZD unproductive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGSHQSE#YGLDVW out-of-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcgggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22304 JY8QFUQ01BSXTY unknown (see comment) Homsap IGHV4-61*02 F (see comment) 535 76.06 143/188 nt 75.0 141/188 nt 10 7 X 10.7.X [2.17.26.X] null + No rearrangement found Low V-REGION identity (76,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'T' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); gtctctggtgactccattaccagtggTtttttactactggaattggatcagacagcccgccgggaGggggactggagtggatcggacgtgtctatattactgggagtgtcaactacagtccatccctcgaacacagagtcagtatatctctagacacgtccaagaaggtctatcttctgaggttggtctc +22305 JY8QFUQ01CBB8N No results +22306 JY8QFUQ01CA1YJ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact +22307 JY8QFUQ01BB7NQ productive (see comment) Homsap IGHV3-7*01 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.16.38.11] CARGSYYHYDMFGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) cctctggatttacttttagcaactattggatgacctgggttcgccaggctccagggaaggggctggagtgggtggccacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgcatctgcaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgagagggtcgtattatcattatgatatgttcggcgactactggggccagggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22308 JY8QFUQ01BM24H productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [2.17.38.11] CAKEGNLGYFDDW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) gcctctggattcaccctgtgcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22309 JY8QFUQ01AEQKP unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-64*01 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 81 51.11 69/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattccccatcagtggctttagaatgaactgggtccgccaggctccaaggtcttcccgttgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22310 JY8QFUQ01BXV9N productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 889 89.19 198/222 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 10 15 8.10.15 [1.17.38.11] CVTGVKASGGAHAMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tctggattcagtttcagagacgcctggatgaattgggtccgccagtctccagggaaggggctggagtgggttggccgtgttaaaaggaaaactgatggtgggacgtcggaatatgctgcattcgtgaaaggcagattcaccatctcaagagatgattcagaaaacacactgtatctgcaaatgaacagcctggaaatcgacgacacagctgtgtatcgttgtgtcacaggagttaaggcttcggggggggctcacgctatggacgtctggggccaagggaccgcggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc +22311 JY8QFUQ01A74UT productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F or Homsap IGHV4-59*04 F (see comment) 728 82.33 177/215 nt 81.86 176/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-3*01 F 2 8 7 12 8.7.12 [1.17.38.11] CTRRWSGNYPFDYW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (8 AA in JY8QFUQ01A74UT ; 10 AA in Homsap_IGHV4-39*01), and low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); cctctggattcagcttcagtgactactacatgagttgggtccgccagtccccagggaagggactggagtggcttggaaacatctattttaatgGggaacacgtactacaacccgtccctcatgagtcgagtcaccatctccgcagacaagtccagaaaacagttctcactgagactgacctctgtgaccgccgcagactcggctgtgtattattgtacgagacggtggagtggaaattatccatttgactactggggccagggaacgctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22312 JY8QFUQ01DB61A unproductive Homsap IGHV4-39*03 F 907 90.05 199/221 nt 87.78 194/221 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD3-22*01 F 2 10 7 X 10.7.X [2.17.38.11] CARSITLTVVVMNDAFDVW# out-of-frame + in FR2-IMGT at codon 39 of V-REGION: 'TG' (2 nucleotides at position 38 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'CA' (2 nucleotides at position 62 to 63 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'TTG' (3 nucleotides at position 76 to 78 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); gtctccggtggctccatcaacagtagaaaattattatTGggggctggatccgccagcccccCAggggaaggggttTTGggagtggattggAaaatatctattatagtgGggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctgggggccaaggggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggccacagcggccctggggctgcctggtcaaggactacttcctgcgaaccggtgacggtgtcgt +22313 JY8QFUQ01CNKMG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + cctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22314 JY8QFUQ01DI0MX unproductive (see comment) Homsap IGHV3-9*01 F 796 85.65 185/216 nt 85.19 184/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD6-19*01 F 2 7 8 X 7.8.X [1.17.38.11] CGA*RSLVWA#LDLW out-of-frame - stop codons in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) cgttggattcactttaatgaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggcgcatagcgaagcctggtctgggcgccttagatctctggggccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22315 JY8QFUQ01DNADY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 811 85.84 188/219 nt 85.39 187/219 nt Homsap IGHJ3*01 F 142 76.0 38/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'GG' (2 nucleotides at position 160 to 161 in the user submitted sequence), (cause frameshift); atgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGGggcacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtgctctccggcctccaccaagggcccatcggtcttccccccgtggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcc +22316 JY8QFUQ01AOR6O productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 683 80.0 172/215 nt 79.53 171/215 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 99 in the user submitted sequence), (do not cause frameshift) cctctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccacccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22317 JY8QFUQ01A7BVQ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 837 87.16 190/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 1 8 7 11 8.7.11 [2.17.38.11] CARDGEWEMLDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 214 to 214 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 92 in the user submitted sequence), (cause frameshift) gcctccggattcaccttcagtaggtattggatgtattgggtccgccaagctccaggcaaAGggggctggtntgggtctcacgcattaaaagtgtgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacataCtttttgtgcaagagacggggagtgggagatgcttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +22318 JY8QFUQ01DHT4K productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 6 15 8.6.15 [2.17.38.11] CARDMGSGRYFEPYDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 89 in the user submitted sequence), (cause frameshift) agcctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcgtggtaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcacccttctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacgtgtcgtggaactcagg +22319 JY8QFUQ01B95D8 No results +22320 JY8QFUQ01AUADL productive (see comment) Homsap IGHV3-30*07 F 847 87.67 192/219 nt 86.76 190/219 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [2.17.38.11] CASLGSYESSGPRW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); gcctctggattcctcttcagtagttatgctatacactgggtccgccaggctccaggcaaGggggcttgagtgggtggcggttgtttcatatgatggaaataataaattttacgcagactctgtgaaggGgtcgattcagcctctccagagacaactccaagagcacggttgatctgcaaatggacaacttgagatccgaagacacggctgtatattattgtgcgagcctcggttcctatgagagcagtggtccccgatggggcccgggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22321 JY8QFUQ01C3IEC unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 111 65.0 39/60 nt 8 X X 8.X.X [2.10.X.X] null - No rearrangement found gcctccggattcacctttagtagtttctggatgcactgggtccagggcttcttcccccca +22322 JY8QFUQ01B7J6S productive (see comment) Homsap IGHV1-24*01 F 988 96.24 205/213 nt 95.77 204/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); ggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaAaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +22323 JY8QFUQ01BV9XN unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CVGQERWPPSEPPV#W out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcagttttagtaattatgtcatgacttgggtccgccaggctccagggaaggggctggagaggatttgtcttataagtggtagtggtgctaggacatcctacgcagactccgtgaagggccggttcaccatctcccgagacaactccgagaacaaggtgtctctgcagatgaacaacctgagagccgaagacacggccatatattactgtgtggggcaagaacgatggccaccgtcggagccccccgtcctggggccagggaactgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22324 JY8QFUQ01CGUN6 productive Homsap IGHV1-3*01 F 863 89.3 192/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tgggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggctttttccccca +22325 JY8QFUQ01BGYG5 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 55 100.0 11/11 nt 1 X X 1.X.X [2.X.X.X] null + No rearrangement found gcctctggatt +22326 JY8QFUQ01CIQN4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt 86.7 189/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CVKESSPWGGDDYFDFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift); cctctggatttaacttCgggcagctatgccatgagctggGgtccgccaggctccagggGAagggggctggagtgggtctcacttattactggtcgtggagatcgcacaaattacgcagagtctctggagggtcggttcaccatctccagagacaattccgacaacactctttatcttcaaatgaacagcctgagagccgaagacacggccatatattactgtgtgaaagagtcttctccctgggggggtgacgactactttgacttttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +22327 JY8QFUQ01AZGQ9 unproductive Homsap IGHV4-39*03 F 996 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD6-13*01 F 2 10 7 X 10.7.X [1.17.38.11] CARDRYVVDSSWYGNIFRTP## out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtactagCttactactggggctggatccgccagcccccagggaaggggctggagtggattggtaacattcattctagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcagacacggccgtgtattattgtgcgagagatcgatatgtcgtggacagtagctggtacggcaacatttttcgaacccctgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +22328 JY8QFUQ01CP28N unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt +22329 JY8QFUQ01CLYL9 productive Homsap IGHV3-30*04 F, or Homsap IGHV3-30-3*03 F 873 89.4 194/217 nt Homsap IGHJ1*01 F (see comment) 179 82.69 43/52 nt Homsap IGHD2-21*02 F 2 8 8 8 8.8.8 [1.17.38.11] CSSGGDYPNW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcgacttcgatggccgtgctatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatctcatatgatggaaatgataaaaactacgcagactccgtgaggggccgattcaccatctccagagacaattctaaggacacgctgtttttgcaaatgaacagcctgagacatgaagacacgggtgaatatttctgttcttcaggaggtgactacccgaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +22330 JY8QFUQ01BX6MG productive Homsap IGHV3-11*01 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 2 8 8 18 8.8.18 [1.17.38.11] CAGSFCGGGCLWPTYHFENW in-frame + ctctggattcccctttaaggactactccatgaactggatccgccaggctccagggaagggactggagtggatttcatacatgagcagcactggtgagaccatatattacgcggactttgtgaagggccgattcaccatctccagggacaccgccaagaatctgttgtttctgcaaatgaattacctgcgagacgaggacacggccatgtattactgtgcgggatcattttgtggtggtggctgcttgtggcccacatatcactttgaaaactggggccagggagccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22331 JY8QFUQ01CE5GY unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1090 100.0 219/219 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [2.17.38.11] CARGHCISTSCYWEIHYYYGMDV## out-of-frame - gcctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactca +22332 JY8QFUQ01B12BF productive (see comment) Homsap IGHV4-61*02 F 816 85.91 189/220 nt 85.0 187/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 10 7 18 10.7.18 [1.17.37.11] CAREDYYGSGSYGRAWFDSW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) tctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtCgggggtgtcgactacaaccctccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagaggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22333 JY8QFUQ01BCS41 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 928 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 79 to 81 in the user submitted sequence), (do not cause frameshift); gcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22334 JY8QFUQ01AR779 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 12 8.8.12 [1.17.38.11] CAKDRGYSYGFDYW in-frame + cctctggattcacctttaccacctatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtctcgactatgagtggtagtggtggtagcacattctacgcggactccgtgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctacaaatgaacagcctgagagccgaggacacggccgtttattattgtgcgaaagatcgaggatacagctatggctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +22335 JY8QFUQ01BSPH1 No results +22336 JY8QFUQ01DH3S3 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 897 90.0 198/220 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found agcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22337 JY8QFUQ01A56SJ unproductive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*05 F 867 89.72 192/214 nt 88.79 190/214 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD3-10*02 F 1 8 8 20 8.8.20 [0.17.38.11] CARVGGR***RLLCRGDAMDVW in-frame + stop codons Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 71 of V-REGION: 'T' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); tggatacaccttCccccgaccactatgtacactgggtgcgacaggcccctggacaagggcttgagtggatgggacggatcagccctaacactggcggcgcacactatggacagaggtTttcagggcagggtcaccatgaccagggacacgtccatcaccacagtctacatggaattgagcaggctgagtccggatgacacggccgtgtattattgtgcgagagttggggggagatgatgatgacggttactatgtcggggagacgctatggacgtctggggccaggggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggngccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +22338 JY8QFUQ01AA6GL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [2.17.38.11] CAKDLFQVSTTYFDYW in-frame + gcctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +22339 JY8QFUQ01AOMJ0 unproductive Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD5-12*01 F 2 7 8 X 7.8.X [1.17.38.11] CARDQVTEDY## out-of-frame - in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactgggggccagggaaccctggtcagtgtctcctcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcagg +22340 JY8QFUQ01CDKRX No results +22341 JY8QFUQ01B28Z6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggGggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22342 JY8QFUQ01CBDVF productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [2.17.38.11] CARGDGVKDDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'A' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); gtctctggattcaccgtcaatagaaAactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +22343 JY8QFUQ01DL5J0 No results +22344 JY8QFUQ01CD2W2 productive (see comment) Homsap IGHV3-7*01 F 1027 96.8 212/219 nt 96.35 211/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtacctattggatgggctgggtccgccaggctccagGggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +22345 JY8QFUQ01C7A9V unproductive Homsap IGHV3-7*01 F 920 90.95 201/221 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [2.17.38.11] CARDSPHQP#DPW out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cagcctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcttctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccccatcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcaccgtccgagagcacagcggccctgggctgcctggtccaaggactcacttccccgaaccggtgacggtcgtcgtgaactcagg +22346 JY8QFUQ01C385E productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.18 194/220 nt 85.91 189/220 nt Homsap IGHJ1*01 F 98 65.38 34/52 nt Homsap IGHD4-23*01 ORF 2 8 8 17 8.8.17 [2.17.38.11] CAKNNPPYDRSGPLYRLLG in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 130 to 130 in the user submitted sequence), (cause frameshift); agcctcctgggttcattttggccacnataccatgagGcttggtccgccaggctccagGggaaggggctggagtgggtctcGaactattggGtaatagtggtgatattacatactacgcagactccgcgaGggggccggttcaccatctccagagacaattcccagaacacactgtatctgcaagtgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaaataaccccccctatgacaggagtggtccattataccgactactgggggccaggggaatcctggtcaccgtctcttcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag +22347 JY8QFUQ01CCG46 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); ctccggattcacctTttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacacgcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22348 JY8QFUQ01B3796 No results +22349 JY8QFUQ01CP3KB unproductive Homsap IGHV3-7*01 F 1027 96.8 212/219 nt 96.35 211/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CAISSGFLLDG#YW out-of-frame + in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggttttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca +22350 JY8QFUQ01C66E4 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 121 54.48 73/134 nt 8 8 X 8.8.X [2.17.9.X] null + No rearrangement found stop codons gcctctaaattcacctttagcaactatgccatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc +22351 JY8QFUQ01AZ7EU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 94 61.29 38/62 nt Homsap IGHD2-15*01 F 2 8 8 21 8.8.21 [1.17.38.11] CAKTGGQCSGGNCYLHYYGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctaaattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcacaggtattagtggtggtggtgaaaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagagcatgttgtatctgcaaatgaacagcctgagagccgaagacacggccgtattttactgtgcgaaaactggcggtcaatgcagtggtggtaactgctatttgcactactacggtatggacgtctggggccaaagggaccacggtcaccgtctcctcatcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaacgtggtcatcgcctgcctggtccagggcttcttccc +22352 JY8QFUQ01A7FKM productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 950 93.12 203/218 nt 91.74 200/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggAaaaggcctggagtggatGggggatcatctatcctggtacctctgagaccagatacagccCcgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22353 JY8QFUQ01BYYQ5 productive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22354 JY8QFUQ01BYVH4 unknown (see comment) Homsap IGHV3-7*02 F 109 59.04 49/83 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22355 JY8QFUQ01CC47V unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CANEVGYCSGRG# out-of-frame - in FR3-IMGT at codon 88 of V-REGION: 'A' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgAtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtcgggggggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag +22356 JY8QFUQ01B2LDP productive (see comment) Homsap IGHV3-7*01 F 885 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD4-23*01 ORF 3 8 8 12 8.8.12 [0.17.38.11] CARGTSVDPGIDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tggattcaccttTtagtaattattggatgcactgggtccgccaggtttcagggaGgggggctggagtgcgtggccaccataaacgaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactctctgtttttgcagatgaacagcctgagagccgaggacacggctgtctactactgtgcgagagggacctcagtggacccggggattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +22357 JY8QFUQ01DABIC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame + gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22358 JY8QFUQ01CR05A productive Homsap IGHV3-30*01 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [1.17.38.11] CPKTGPGHSSPFDYW in-frame + cctctggattcaccttccgaagttatgatctgcactgggtccgccaggctccaggcaaggggctagagtgggtggcatttatatcaaacgatggaagtgacacagactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaagacgctatatctgcaaatgaacagcctgagagttgaggacacggctgtgtattactgtccgaaaaccggccccggtcatagcagcccctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +22359 JY8QFUQ01C8W1E No results +22360 JY8QFUQ01AQ6MS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 996 95.0 209/220 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [2.17.38.11] CARPYCGGDCHNRGAFDIW in-frame - ggcctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22361 JY8QFUQ01AF1QO unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1051 97.3 216/222 nt 96.85 215/222 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [2.17.38.11] CARLDYTR*FDYW in-frame + stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggGggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtagtttgactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +22362 JY8QFUQ01BZOJU productive Homsap IGHV3-9*01 F 892 89.95 197/219 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVKGAGTTVNWFDIW in-frame + cctctgggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +22363 JY8QFUQ01ASIT3 productive (see comment) Homsap IGHV3-7*01 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [1.17.38.11] CARVIPGRGNYAFDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 89 of V-REGION: 'T' (1 nucleotides at position 170 to 170 in the user submitted sequence), (cause frameshift); ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatTttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +22364 JY8QFUQ01B3LY5 unknown (see comment) Homsap IGHV1-45*01 F, or Homsap IGHV1-45*02 F or Homsap IGHV1-46*01 F or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F or Homsap IGHV1-69*01 F or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F 102 58.97 46/78 nt 57.69 45/78 nt 1 X X 1.X.X [24.X.X.X] null + No rearrangement found in FR1-IMGT, from codon 7 of V-REGION: 2 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) cctgagttccacgacaccgtcaccggttcgggggaagtagtccttgaccaggcagcccagggccgctgtgccccccagaggtgctcttggaggagggtgccaggggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga +22365 JY8QFUQ01CE0WI productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 962 94.42 203/215 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD4-17*01 F 3 8 7 16 8.7.16 [1.17.38.11] CARGSVTTWRRENWFDPW in-frame - tctctggtggctccatcagtacttattactggaactggatccggcagcccccagggaagggactggagtggattgggtatatccataacagtgggagtagcaactacaacccctccctcaagagtcgagtcaacatatctgtagacgcgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtttattactgtgcgagaggttcggtgactacgtggagacgggagaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22366 JY8QFUQ01BFMOW unproductive Homsap IGHV3-11*01 F 883 89.5 196/219 nt 88.58 194/219 nt Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CARDDSCSGGSCYEY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); acctctggattcagtttcagtgactactacatgagttggatccgccaggctccagggagGggggctggagtgggtttcatatattgatagcggtggtaccgccatgtactactcagactccgtgaaggGgccgattcaccatctccagggacaacgccaagaagtcactgtttctgcaaatgagtagcctgagagccgaagacacggccgtgtactattgtgcgagagatgactcttgtagtggtggtagctgttacgaatactgggggccagggaaccccggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggggctt +22367 JY8QFUQ01CAGQP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt 94.98 208/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); gcctctggattcaccttTtagaagctatgccatgagctgggtccgccaggttccagggaaggGggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +22368 JY8QFUQ01B8CLS unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*07 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.37.11] CVRDDDTSGHYSLFKY## out-of-frame - in FR3-IMGT, from codon 96 of V-REGION: 1 nucleotides (from position 195 in the user submitted sequence), (cause frameshift) ggctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagcgaggacacggctgtatattactgtgtgagagatgatgataccagtggtcactactctctgtttaaatattgggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttccccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22369 JY8QFUQ01A3PQF unproductive (see comment) Homsap IGHV4-61*02 F 903 89.69 200/223 nt 88.79 198/223 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 10 7 X 10.7.X [2.17.38.11] CARQGG**WTLE*LL# out-of-frame + stop codons in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 121 to 121 in the user submitted sequence), (cause frameshift); tgtctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctGcccagaggggacagcaactacaaccCcctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaagggggatagtagtggaccctggaatgactactgggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcaccagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22370 JY8QFUQ01B6UM2 productive (see comment) Homsap IGHV3-33*04 F (see comment) 706 81.02 175/216 nt 80.09 173/216 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.16.38.11] CARDILDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 45 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) catttggattccctttcagcgactatggcatgcactgggtccgcagactccagacaagggactagaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22371 JY8QFUQ01CR7D8 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1040 97.71 213/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaaccgaaactactggggccagggaagccctggctgnaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +22372 JY8QFUQ01CKDV6 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 859 88.89 192/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 124 72.0 36/50 nt Homsap IGHD2-15*01 F 3 8 7 X 8.7.X [2.17.38.11] CARDPRDYCSGGYCFVGAFDI## out-of-frame - gtctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgataggaactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctgggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22373 JY8QFUQ01B2WGC productive (see comment) Homsap IGHV4-59*08 F 881 90.23 194/215 nt 88.84 191/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARNPSYSNSHQHCDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'CA' (2 nucleotides at position 53 to 54 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccCAgggaaggggcctggagtggattggttatgtctattatactggGgggcaccgactccaaccCcctccctcaagagtcgagtcgccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctatttttgtgcgagaaatccctcttatagcaattcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccag +22374 JY8QFUQ01CGJDB productive (see comment) Homsap IGHV4-4*07 F (see comment) 715 81.48 176/216 nt 80.56 174/216 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-9*01 F 1 8 7 16 8.7.16 [2.17.38.11] CARECLDSLGRPSHLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'CTGACT' (6 nucleotides at position 26 to 31 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); gtctctggtggcccgatcaagaataCTGACTactattggacatggatccggcagcccgccgggaggggactggagtgggtcgggcgtgtctatttgaatggcaatgccgactacaaccCcctccttcagcagccgtctcaccatgtccattgacacgtccaggaaccaattctccctgagcttgacctctgtgaccgccgctgacacggccctctattactgtgcgagagaatgtcttgattcacttggcagaccgagtcaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22375 JY8QFUQ01B4LPL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 154 89.47 34/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found tctctggattcacctttgacagctacgccatgagctgg +22376 JY8QFUQ01CBLC4 unproductive (see comment) Homsap IGHV3-7*01 F 945 93.09 202/217 nt 92.17 200/217 nt Homsap IGHJ1*01 F (see comment) 80 61.54 32/52 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.37.11] CAISSDFYSTGH# out-of-frame + stop codons Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 87 of V-REGION: 1 nucleotides (from position 165 in the user submitted sequence), (cause frameshift) gctctggattcaacttcagaacctattagatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataAaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcatgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactgggccagggaaccctggtcaccgtctctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc +22377 JY8QFUQ01BZIXK productive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*05 F 876 90.19 193/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [0.17.38.11] CAREKRGQHDGSRFATNDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacacattcaccggctactatgtgcactgggtgcggcaggCcccctggacaaggtcttgagtggatgggacggatgaaccctaacagtggtgccacagactctgcacagaagtttcagggcagggtcaccatgaccagggacacgtccgtcaacacatattacatggagttgagcggactgaaatctgacgacacggccatctactactgtgcgagagagaagcggggacagcatgatggaagtcgttttgccacaaatgacttttggggctcgggaaccctggtcaccgtctccccgaccatccccgaccagccccaaggtcttcccgctgagcctctgagcaccccagccagatgggaacgtggtcatccgcctgctggtccaggggcttcttcccccca +22378 JY8QFUQ01CDBGI productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 971 92.86 208/224 nt 90.62 203/224 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD5-24*01 ORF 3 8 10 11 8.10.11 [1.17.38.11] CTPLARRDVLRMG in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'AT' (2 nucleotides at position 170 to 171 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'T' (1 nucleotides at position 204 to 204 in the user submitted sequence), (cause frameshift); cctctggattcacCttttagtaaccattggatgaactgggtccgccaggctccagggaaGggggctggagtgggttgGgccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaaATcacgttttatctgcaaatgaatagcctaaaaaTccgaagacacagccgtctattactgtaccccacttgcgagaagagatgtcttacgaatgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgccatggtccagggcttcttccccca +22379 JY8QFUQ01CRKNP unproductive Homsap IGHV3-48*03 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CARESWWSGFYGWYD#PW out-of-frame + cctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +22380 JY8QFUQ01A7Z64 unproductive (see comment) Homsap IGHV3-30*15 F 950 93.12 203/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F (see comment) 96 66.67 32/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARDELPWGYNR#YYFDYW out-of-frame + stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'T' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); cctctggattcaccttTtagtagatattccatgcactgggtccgccaggctccaggcaaggGggctagagtgggtggcacttatatcatacgatggaagtagaagaatctacgcagactccgtgaagggccgattcaccatctccagagacacttccaagaacacggtgtatctgcaaAatgagtagcctgagacctgaggacacggctgtgtaTttactgtgcgagagatgagctgccttggggatacaatagaatactactttgactattggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcatcgcctgcctggtccagggcttcttccc +22381 JY8QFUQ01BJ0EY unproductive Homsap IGHV4-61*02 F 925 90.99 202/222 nt 89.19 198/222 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD2-2*01 F 3 10 7 X 10.7.X [2.17.38.11] CARVVRCTTTGCSRGRMVRPP## out-of-frame - Other possibilities: Homsap_IGHJ1*01 and Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 31 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); tctctgggtggctccatcaGgcagtgatgattactactggGagctggatccggcaGgcccgccgggaagggactggagtggattgggcgtatctcttccagtgGggaacaccaactacaacccctccctcaggagtcgagtcaacatttcactagacacgtccaagacccagttctccctggagctgacctctgtgagcgccgcagacacggccgtgtattactgtgcgagggtcgttcgttgtactacgaccggctgctcaaggggtaggatggttcgaccccctgggggccaggggaaccctggtaaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccccagg +22382 JY8QFUQ01BEDF2 unproductive (see comment) Homsap IGHV3-7*01 F 982 94.52 207/219 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [2.17.38.11] CARGTSVDPGD#DHW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactctctgtttttgcagatgaacagcctgagagccgaggacacggctgtctactactgtgcgagagggacctcagtggacccgggggattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttcccccca +22383 JY8QFUQ01DLVYV No results +22384 JY8QFUQ01AQFZJ unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 107 56.7 55/97 nt 55.67 54/97 nt 8 X X 8.X.X [17.6.X.X] null - No rearrangement found in FR1-IMGT, from codon 18 of V-REGION: 22 nucleotides (from position 111 in the user submitted sequence), (cause frameshift) ggggggaagaagccctggaccaggcaggcgatgaccacgttcccatctggctgggtgctgcagaggctcagcgggaagaccttgggggctggtcgggggatgctggggggccgccggatccaactccagtagtaaccagtcatggagccaccagagaca +22385 JY8QFUQ01AFGXD productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); ggttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgGggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22386 JY8QFUQ01AG6QZ No results +22387 JY8QFUQ01AXVCI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagtacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22388 JY8QFUQ01BRKSA productive (see comment) Homsap IGHV3-30*01 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggGggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22389 JY8QFUQ01BCNU6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt 91.24 198/217 nt Homsap IGHJ2*01 F 121 69.81 37/53 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVVWSLWYFDL## out-of-frame - in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tctaacattcgcctttagcaactGatgccatgagctgggtccgccaggctccGagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctgggggccgtggcaccctggtcactgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag +22390 JY8QFUQ01AEQJJ No results +22391 JY8QFUQ01BLLNO unproductive Homsap IGHV3-48*01 F 946 92.69 203/219 nt 90.87 199/219 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [2.17.38.11] CARERGNSYGEIDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 181 to 181 in the user submitted sequence), (cause frameshift); cctctggttttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaagGgggctggagtgggtTttcatacattagcagtagtactactaccaAaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaAatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggcccaagggaaccctggtcaccgtctcctcagcttccacaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22392 JY8QFUQ01DH48J No results +22393 JY8QFUQ01BM3SO productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F (see comment) 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDMGSGRYLEALDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); gtctgacctcatatttactaaatatggcGttccactgggtccgccaggctccaggcaaggggctggagtgggtggcacttatttggtttgatggaagtaataaatattatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatggacagcctgagagccgaggacacggctgtgtatttctgtgcgaaggatatgggttcgggaagatacttagaagctcttgaccactggggcccgggaatccaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca +22394 JY8QFUQ01CMXMD unproductive (see comment) Homsap IGHV3-72*01 F 899 89.29 200/224 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD2-15*01 F 3 8 10 10 8.10.10 [1.17.38.11] CAVAAPPL*RLG in-frame + stop codons cctctggattcaccttaagtgacttctacatggactggctccgccaggctccagggaaggggctggagtgggttggtcgcagtagaaacaaagctaatggttacagtacacaattcgccgcatctgtgatgggcagattcaccatctcaagagatgactcaaagaatttactatatctacaaatgagcagcctgaaaaccgaggacacggccatttattactgtgctgtcgcagccccccccttatgacggctgggggccagggaacccctggtcatcgtctcctcagcatccccggaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttctt +22395 JY8QFUQ01B2WG4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 774 84.33 183/217 nt 82.95 180/217 nt Homsap IGHJ1*01 F 170 80.77 42/52 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARPDGGNGWAAKYFQMW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'GG' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctgggttctcgtttaatagttatggcatgacatggttccgccaggctccgggggaggGGggctggagtgggtctcatctataactggaactggGgggtaacgttttctacgcagacttcgtgCaggggccggttcaccatctccagagacaattccgacaatatgttgtttctgcaaatgaacagcctgagagttgaggacacggccgtgtattactgtgcgagacctgacggaggcaatggctgggccgcaaagtactttcagatgtggggccagggcacccttctcaccgtctccccagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgagaacgtggtcatcgcctgcctggtccagggcttcttccccccagg +22396 JY8QFUQ01AXTRO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgCaggggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgcccctgctccaggagcacctccgagagcacagcggccctggggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcagg +22397 JY8QFUQ01CPLK2 unproductive Homsap IGHV3-11*01 F 811 85.84 188/219 nt 85.39 187/219 nt Homsap IGHJ4*03 F (see comment) 114 70.83 34/48 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [2.17.38.11] CADIKLGDWCFDL## out-of-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift); cctctgaaaatcaccttcagcgaccactacatgagctggatccgccaggctccagggaaAGggggctggaatggatttcatatattagcaccagtggtaatatgatctattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaggtcgatgtatttgcagatgaacagtctgagagccgaggacacggccgtctatttctgtgccgatataaaactgggtgactggtgcttcgatctctgggggccgtggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccaa +22398 JY8QFUQ01B7Y6H No results +22399 JY8QFUQ01CY6T7 productive Homsap IGHV1-18*01 F 885 90.65 194/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-10*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARVIRTNWLDPW in-frame + tggttacacctttactacctatggcgtcacctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggtaatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacagccgtatattattgtgcgcgagtgattcggaccaactggctcgacccctggggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc +22400 JY8QFUQ01DDCM1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [2.17.38.11] CAKEGPTLLTRPPS##W out-of-frame + gcctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaacttttggtggtagtggtggttctacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctatatcttcaaatgagcagcctgagagccgaggacacggccatatacttctgtgcgaaagaaggacctacgcttctaactcgccccccctctcaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc +22401 JY8QFUQ01CKM9V No results +22402 JY8QFUQ01BN21I No results +22403 JY8QFUQ01CGCIW productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 911 90.5 200/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagTcccccagggaaggGggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22404 JY8QFUQ01CLDIN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt 91.67 198/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 7 13 8.7.13 [2.17.38.11] CARGPRSRGYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'GTG' (3 nucleotides at position 91 to 93 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'T' (1 nucleotides at position 157 to 157 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) gcctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggGAagggggctggaatgggtctcaactattactaGTGgtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaattTtcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag +22405 JY8QFUQ01AUOFB No results +22406 JY8QFUQ01C3T62 productive Homsap IGHV3-7*01 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + gctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc +22407 JY8QFUQ01AL9R5 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 789 86.26 182/211 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-6*01 F 2 8 7 X 8.7.X [0.17.38.11] CARDSSNWSDA#FDIW out-of-frame - stop codons tggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgctttttgatatctggagccaagggacaatggtcaccgtctcttcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22408 JY8QFUQ01BMYC6 unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 121 54.48 73/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc +22409 JY8QFUQ01BZ3AC productive Homsap IGHV3-7*01 F 944 93.49 201/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVRPPGRRLDIW in-frame - ctggattcacctttagtaattattggatgacgtgggtccgccaggctccagggaaggggctggagtgggtggccaacataaatggagatggaagtgggcaacaatatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacttactgtatctgcaaatgaacagcctgagagccgaggacactgctgtatattactgtgtgagacccccaggtcgtcgtcttgatatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22410 JY8QFUQ01BKPPK unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1013 96.33 210/218 nt 95.87 209/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD2-2*02 F 2 8 8 X 8.8.X [1.17.38.11] CAKDRVYGGGEPLDH## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggGggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggcccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22411 JY8QFUQ01C81UR No results +22412 JY8QFUQ01BNXXZ No results +22413 JY8QFUQ01BOUIW productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 876 90.19 193/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 6 15 8.6.15 [1.17.38.11] CARDQSPGVAVAGPDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 81 in the user submitted sequence), (cause frameshift) ttcgggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgtttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcaaagtccgggtgtagcagtggctggtcctgattactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaangtggtcgtcgcatgcctggtccagggcttcttccccc +22414 JY8QFUQ01DGOL4 unknown (see comment) Homsap IGHV3-7*01 F 1041 96.82 213/220 nt 96.36 212/220 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); agcctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag +22415 JY8QFUQ01CEU9H unproductive (see comment) Homsap IGHV3-48*02 F 967 94.44 204/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARPAGEGDPFFHYYSGLDVW in-frame - stop codons tctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtagatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22416 JY8QFUQ01CWUM4 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 144 53.33 96/180 nt 52.78 95/180 nt 6 8 X 6.8.X [X.17.28.X] null - No rearrangement found stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); tcatcttcagtagctactggatgcactgggtccgccaagctccagggaagGgggctggtgtgggtctcaccgtctccccagcatcccccgaccagccccaaggtcttcccgctgagcctctgagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22417 JY8QFUQ01COSIV unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 123 50.95 107/210 nt 8 8 X 8.8.X [1.17.35.X] null + No rearrangement found ttctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22418 JY8QFUQ01A2S3C productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 870 88.64 195/220 nt 87.27 192/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [2.17.38.11] CAKDFYYGCDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'CT' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 132 to 132 in the user submitted sequence), (cause frameshift); agtctctggattcaacttcagtggctatggcatgcactgggtccgccaggGctccaggcaaggggcCTgggagtgggtggcagtcattgcatacaatggaggaaatatatactacgcagactccgtgaaggGgccgattcaccatctccagagacaattccaaggataccctgtacttgcacatgaccagtctgagacctgatgacacggccatgtattactgtgcgaaagacttttattatggttgcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtctcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctcggtccagggcttccttcccccgaggagccacct +22419 JY8QFUQ01BFKU7 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 541 71.69 157/219 nt Homsap IGHJ1*01 F (see comment) 22 75.0 6/8 nt 8 8 X 8.8.X [2.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (71,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. gcctctgggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc +22420 JY8QFUQ01AARY1 unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F or Homsap IGHV7-81*01 ORF 139 58.88 63/107 nt 8 8 X 8.8.X [0.17.2.X] null - No rearrangement found cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22421 JY8QFUQ01BHRCO unproductive Homsap IGHV4-61*02 F (see comment) 731 81.45 180/221 nt Homsap IGHJ4*02 F (see comment) 114 70.83 34/48 nt Homsap IGHD3-3*01 F 1 10 7 X 10.7.X [1.17.38.11] CARERAPSIDGVRELDF## out-of-frame + Low V-REGION identity (81,45% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) tctctggtgactccattaccagtggtttttactactggaattggatcagacagcccgccgggaggggactggagtggatcggacgtgtctatattactgggagtgtcaactacagtccatccctcgaacacagagtcagtatatctctagacacgtccaagaggcaattcttcttgaggttggtctctgtgaccgccgcagacacggccgtgtattactgtgcgagagagcgggctccttcgattgacggagtgagagaacttgacttctggggccagggggaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22422 JY8QFUQ01CEIUR unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1105 100.0 222/222 nt 99.1 220/222 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [2.17.38.11] CARSRTFYGSANY## out-of-frame + in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagcagtagtagttactactgGgggctggatccgccagcccccagggaaggGggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc +22423 JY8QFUQ01CBRT1 unproductive (see comment) Homsap IGHV3-30*01 F 868 88.94 193/217 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD1-14*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CACGPYA#DGYDVW out-of-frame - stop codons ctctggattcaccttcagtgcctttactatgcactgggtccnccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggcccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22424 JY8QFUQ01BK9ED unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact +22425 JY8QFUQ01AV4SA No results +22426 JY8QFUQ01BC2PX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaGggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca +22427 JY8QFUQ01CA2ZU No results +22428 JY8QFUQ01BLYJ4 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt 86.05 185/215 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-6*01 F 2 8 7 X 8.7.X [1.17.38.11] CARDSSNWSDA#FDIW out-of-frame - stop codons in FR3-IMGT at codon 84 of V-REGION: 'C' (1 nucleotides at position 153 to 153 in the user submitted sequence), (cause frameshift); tctctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccCaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcattttgatatctggagccaagggacaatggtcaccgtctcttcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca +22429 JY8QFUQ01C1IBJ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift); cctctggattcaccTtttaccaactatggcatgagctgggtccgccaggctccagggGAagggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctccgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca +22430 JY8QFUQ01B48C0 productive Homsap IGHV3-33*05 F (see comment) 699 80.0 176/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.17.38.11] CVKGRGYNDYGLDYW in-frame - Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcgtctgggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca +22431 JY8QFUQ01BLN4B productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22432 JY8QFUQ01ARNFI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag +22433 JY8QFUQ01CDTOM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgcccctggggcgcctggtcaaggactaccttccccgaaccggtgagtgtcgtggaact